keyword
MENU ▼
Read by QxMD icon Read
search

Skin and soft tissue infection treatment

keyword
https://www.readbyqxmd.com/read/27917329/minimally-invasive-treatment-of-tibial-pilon-fractures-through-arthroscopy-and-external-fixator-assisted-reduction
#1
Huasong Luo, Liaobin Chen, Kebin Liu, Songming Peng, Jien Zhang, Yang Yi
OBJECTIVE: The aim of this study was to evaluate the clinical outcome of tibial pilon fractures treated with arthroscopy and assisted reduction with an external fixator. METHODS: Thirteen patients with tibial pilon fractures underwent assisted reduction for limited lower internal fixation with an external fixator under arthroscopic guidance. The weight-bearing time was decided on the basis of repeat radiography of the tibia 3 months after surgery. Postoperative ankle function was evaluated according to the Mazur scoring system...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27908758/thermally-triggered-release-of-the-bacteriophage-endolysin-chapk-and-the-bacteriocin-lysostaphin-for-the-control-of-methicillin-resistant-staphylococcus-aureus-mrsa
#2
Hollie Hathaway, Jude Ajuebor, Liam Stephens, Aidan Coffey, Ursula Potter, J Mark Sutton, A Toby A Jenkins
Staphylococcus aureus infections of the skin and soft tissue pose a major concern to public health, largely owing to the steadily increasing prevalence of drug resistant isolates. As an alternative mode of treatment both bacteriophage endolysins and bacteriocins have been shown to possess antimicrobial efficacy against multiple species of bacteria including otherwise drug resistant strains. Despite this, the administration and exposure of such antimicrobials should be restricted until required in order to discourage the continued evolution of bacterial resistance, whilst maintaining the activity and stability of such proteinaceous structures...
November 28, 2016: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/27907197/clinical-experience-of-patients-receiving-doripenem-containing-regimens-for-the-treatment-of-healthcare-associated-infections
#3
Chien-Ming Chao, Chi-Chung Chen, Hui-Ling Huang, Yin-Ching Chuang, Chih-Cheng Lai, Hung-Jen Tang
In this study, we retrospectively reviewed the clinical experience of patients receiving doripenem-containing regimens for the treatment of healthcare-associated infections (HCAIs) in a tertiary care center and assessed the clinical usefulness of doripenem therapy in this clinical setting. In this retrospective study, the medical records of all adult patients who had ever received doripenem-containing therapy for the treatment of HCAIs were reviewed between September 1, 2012 and August 31, 2014, and the following data were extracted: age, gender, type of infection, disease severity, underlying comorbidities or conditions, and laboratory results...
2016: PloS One
https://www.readbyqxmd.com/read/27899072/appropriateness-of-antibiotic-management-of-uncomplicated-skin-and-soft-tissue-infections-in-hospitalized-adult-patients
#4
Thomas L Walsh, Lynn Chan, Chelsea I Konopka, Michael J Burkitt, Matthew A Moffa, Derek N Bremmer, Monika A Murillo, Courtney Watson, Noreen H Chan-Tompkins
BACKGROUND: Skin and soft tissue infections (SSTIs) are a leading cause for hospitalizations in the United States. Few studies have addressed the appropriateness of antibiotic therapy in the management of SSTIs without complicating factors. We aimed to determine the appropriateness of antibiotic treatment duration for hospitalized adult patients with uncomplicated SSTIs. METHODS: This was a retrospective analysis performed at two academic medical centers in Pittsburgh, Pennsylvania on patients aged 18 years and older with primary ICD-9 code for SSTIs admitted August 1st, 2014-March 31st, 2015...
November 29, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27897966/behavioral-characteristics-and-injection-practices-associated-with-skin-and-soft-tissue-infections-among-people-who-inject-drugs-a-community-based-observational-study
#5
Disa Dahlman, Anders Håkansson, Alex H Kral, Lynn Wenger, Elizabeth K Ball, Scott P Novak
BACKGROUND: People who inject drugs (PWID) are at increased risk for bacterial skin and soft tissue infections (SSTIs). While SSTIs pose significant health risks, little is known about their prevalence and characteristics in the population of PWID in the United States. This study investigates whether behavioral factors related to skin and equipment hygiene and tissue-damaging injection practices are associated with recent SSTIs among PWID. METHODS: Active PWID were recruited using targeted sampling in San Francisco in 2011-2013...
November 29, 2016: Substance Abuse
https://www.readbyqxmd.com/read/27895134/vancomycin-and-the-risk-of-aki-a-systematic-review-and-meta-analysis
#6
Abhisekh Sinha Ray, Ammar Haikal, Kassem A Hammoud, Alan S L Yu
BACKGROUND AND OBJECTIVES: Vancomycin has been in use for more than half a century, but whether it is truly nephrotoxic and to what extent are still highly controversial. The objective of this study was to determine the risk of AKI attributable to intravenous vancomycin. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a systematic review of randomized, controlled trials and cohort studies that compared patients treated with intravenous vancomycin with a control group of patients given a comparator nonglycopeptide antibiotic and in which kidney function or kidney injury outcomes were reported...
November 28, 2016: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/27895083/locking-plate-external-fixation-and-negative-pressure-wound-therapy-for-treatment-of-a-primary-infection-in-a-closed-clavicle-fracture
#7
Robert M Kenyon, David I Morrissey, Diarmuid C Molony, John Francis Quinlan
Infection in a clavicle fracture is uncommon, but remains a challenging problem. A paucity of soft tissue coverage often combined with significant displacement and interfragmentary movement add complexity to an already difficult situation for effective infection treatment. External fixation in principle offers a means of achieving fracture stability, while the infection is being eradicated. We present the case of a closed clavicle fracture, initially treated conservatively, that presented 5 weeks later with infection...
November 28, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27894236/virulence-factor-targeting-of-the-bacterial-pathogen-staphylococcus-aureus-for-vaccine-and-therapeutics
#8
Trevor Kane, Katelyn Carothers, Shaun Lee
Staphylococcus aureus is a major bacterial pathogen capable of causing a range of infections in humans from gastrointestinal disease, skin and soft tissue infections, to severe outcomes such as sepsis. Staphylococcal infections in humans can be frequent and recurring, with treatments becoming less effective due to the growing persistence of antibiotic resistant S. aureus strains. Significant research into virulence factors produced by S. aureus have yielded many important findings regarding specific mechanisms that contribute to its overall pathogenesis...
November 28, 2016: Current Drug Targets
https://www.readbyqxmd.com/read/27887585/reduction-in-antibiotic-prescribing-for-respiratory-tract-infections-in-swedish-primary-care-a-retrospective-study-of-electronic-patient-records
#9
Mia Tyrstrup, Anders Beckman, Sigvard Mölstad, Sven Engström, Christina Lannering, Eva Melander, Katarina Hedin
BACKGROUND: Swedish studies on antibiotic use in primary care have been based on one-week registrations of infections. In order to study adherence to guidelines, analyses based on large databases that provide information on diagnosis linked prescriptions, are needed. This study describes trends in management of infections in Swedish primary care particularly with regards to antibiotic prescribing and adherence to national guidelines. METHODS: A descriptive study of Sweden's largest database regarding diagnosis linked antibiotic prescription data, the Primary care Record of Infections in Sweden (PRIS), for the years 2008, 2010 and 2013...
November 25, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27876477/current-prescribing-practices-for-skin-and-soft-tissue-infections-in-nursing-homes
#10
Diana Feldstein, Philip D Sloane, David Weber, Kimberly Ward, David Reed, Sheryl Zimmerman
OBJECTIVES: Antibiotic stewardship has been called for across all sites of health care, including nursing homes (NHs). Skin and soft tissue infections (SSTIs) are the third most common indication for antibiotics in the NH, and so should be a focus of stewardship. This study audited medical records to identify signs and symptoms of SSTIs treated with antibiotics in relation to the McGeer criteria for surveillance, the Loeb minimum criteria for antibiotic initiation, and prescribing recommendations of the Infectious Disease Society of America...
November 18, 2016: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/27876059/a-prospective-observational-cohort-study-in-primary-care-practices-to-identify-factors-associated-with-treatment-failure-in-staphylococcus-aureus-skin-and-soft-tissue-infections
#11
Grace C Lee, Ronald G Hall, Natalie K Boyd, Steven D Dallas, Liem C Du, Lucina B Treviño, Sylvia B Treviño, Chad Retzloff, Kenneth A Lawson, James Wilson, Randall J Olsen, Yufeng Wang, Christopher R Frei
BACKGROUND: The incidence of outpatient visits for skin and soft tissue infections (SSTIs) has substantially increased over the last decade. The emergence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has made the management of S. aureus SSTIs complex and challenging. The objective of this study was to identify risk factors contributing to treatment failures associated with community-associated S. aureus skin and soft tissue infections SSTIs. METHODS: This was a prospective, observational study among 14 primary care clinics within the South Texas Ambulatory Research Network...
November 22, 2016: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/27871233/a-retrospective-analysis-of-melioidosis-in-cambodian-children-2009-2013
#12
Paul Turner, Sabine Kloprogge, Thyl Miliya, Sona Soeng, Pisey Tan, Poda Sar, Pagnarith Yos, Catrin E Moore, Vanaporn Wuthiekanun, Direk Limmathurotsakul, Claudia Turner, Nicholas P J Day, David A B Dance
BACKGROUND: Melioidiosis, infection by Burkholderia pseudomallei, is an important but frequently under-recognised cause of morbidity and mortality in Southeast Asia and elsewhere in the tropics. Data on the epidemiology of paediatric melioidosis in Cambodia are extremely limited. METHODS: Culture-positive melioidosis cases presenting to Angkor Hospital for Children, a non-governmental paediatric hospital located in Siem Reap, Northern Cambodia, between 1(st) January 2009 and 31(st) December 2013 were identified by searches of hospital and laboratory databases and logbooks...
November 21, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27849331/-fournier-s-gangrene-after-anorectal-surgery-in-infant-two-case-reports
#13
Murat Sütçü, Güntulu Duran Şık, Feryal Gün, Ayper Somer, Nuran Salman
Necrotizing fasciitis is a life-threatening soft tissue infection characterized by progressive necrosis of the skin, subcutaneous tissues and fascia. Fournier's gangrene (FG) is a serious and aggressive form of infective necrotizing fasciitis involving perineal region and genitalia. Presently described are 2 pediatric cases of FG with widespread necrosis of surrounding tissue following anorectal surgery, causing severe septic shock. Case 1: Six-month-old female patient with anal stenosis and duplication presented at emergency clinic with fever, somnolence, irritability, and feeding difficulty...
September 2016: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/27848910/-the-pitfalls-of-necrotising-soft-tissue-infection-a-wake-up-call-for-surgeons
#14
V M de Jong, J C Goslings
Necrotising soft tissue infections require early consultation of an experienced surgeon, regardless of what time of day they occur. Delays in diagnosis and treatment should not occur. Necrotectomy should be skin-sparing when possible. A low threshold for consultation with a tertiary referral center is recommended.
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27844118/the-cost-of-infection-in-severe-open-tibial-fractures-treated-with-a-free-flap
#15
Ulrik Kähler Olesen, Nicolas Jones Pedersen, Henrik Eckardt, Line Lykke-Meyer, Christian Thorsten Bonde, Upender Martin Singh, Martin McNally
PURPOSE: Open tibial fractures needing soft tissue cover are challenging injuries. Infection risk is high, making treatment difficult and expensive. Delayed skin closure has been shown to increase the infection rate in several studies. We aimed at calculating the direct and indirect cost of treatment, and to determine the effect of delayed skin closure on this cost. METHODS: We reviewed all records of patients treated with a free flap in our institution for an open tibial fracture from 2002 to 2013...
November 14, 2016: International Orthopaedics
https://www.readbyqxmd.com/read/27836315/elderly-patients-are-at-increased-risk-for-treatment-failure-in-outpatient-management-of-purulent-skin-infections
#16
John P Haran, Eric Wilsterman, Tyler Zeoli, Francesca L Beaudoin, Jennifer Tjia, Patricia L Hibberd
OBJECTIVE: Current Infectious Disease Society of America (IDSA) guidelines for the management of purulent skin or soft tissue infections do not account for patient age in treatment recommendations. The study objective was to determine if age was associated with outpatient treatment failure for purulent skin infection after adjusting for IDSA treatment guidelines. METHODS: We conducted a multicenter retrospective study of adult patients treated for a purulent skin infection and discharged home from four emergency departments between April and September 2014...
October 29, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27832748/invasive-mucormycosis-in-children-an-epidemiologic-study-in-european-and-non-european-countries-based-on-two-registries
#17
Zoi Dorothea Pana, Danila Seidel, Anna Skiada, Andreas H Groll, Georgios Petrikkos, Oliver A Cornely, Emmanuel Roilides
BACKGROUND: Mucormycosis has emerged as a rare but frequently fatal invasive fungal disease. Current knowledge on paediatric mucormycosis is based on case reports and small series reported over several decades. Contemporary data on a large cohort of patients is lacking. METHODS: Two large international registries (Zygomyco.net and FungiScope™) were searched for mucormycosis cases in ≤19 year-old patients. Cases enrolled between 2005 and 2014 were extracted, and dual entries in the two databases merged...
November 10, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27814724/severe-open-lisfranc-injuries-one-stage-operation-through-internal-fixation-associated-with-vacuum-sealing-drainage
#18
Wenqing Qu, Shuqin Ni, Zhenhai Wang, Yong Zhao, Shimin Zhang, Yiheng Cheng, Tong Liu, Min Yu, Dan Wang
BACKGROUND: This study aimed to investigate the clinical feasibility of treating severe open Lisfranc injuries by means of one-stage internal fixation with k-wires associated with vacuum sealing drainage (VSD). METHODS: The clinical outcomes of 20 cases of severe open Lisfranc joint fracture-dislocation treated by using one-stage internal fixation with k-wires associated with VSD, after debridement and suturing during emergency treatment, were reviewed. RESULTS: At 6 and 12 months after surgery, the American Orthopaedic Foot and Ankle Society midfoot scores were 69...
November 4, 2016: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/27813433/factors-affecting-the-rise-of-treatment-of-resistant-bacteria-in-skin-and-soft-tissue-infections-in-the-united-states-1993-2012
#19
Margaret E Wetzel, Alan B Fleischer
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections (SSTIs) prevalence has been steadily increasing for the past 40 years. The increase in such infections has contributed to a change in the treatment patterns of the patient. This study aimed to detail the factors determining prescription practices associated with MRSA-related skin and soft tissue infections. METHODS: The National Ambulatory Medical Care Survey (NAMCS) was searched for data from 1993 to 2012 regarding the factors associated with resistant vs...
November 22, 2016: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/27811344/evaluating-the-effectivenes-of-antiseptic-solution-decasan-in-treatment-of-necrotic-soft-tisue-diseases
#20
Julia Fuss, Victor Palii, Anna Voloboyeva
: Sepsis is a severe generalised infection caused usually by pathogenic bacteria. It is often the cause of hospitalization and death in patients treated in intensive care and other hospital wards. Latest research brought to better understanding of patomechanisms, took place significant development of therapy heading to improvement of general patients condition treated as a basis and additionally supported by local therapy. The aim of the study was to evaluate the possibility of using the solution Decasan in the comprehensive treatment of patients necrosis of soft tissues...
October 1, 2016: Polski Przeglad Chirurgiczny
keyword
keyword
63260
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"