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https://www.readbyqxmd.com/read/29310728/bdnf-and-nrg1-polymorphisms-and-temperament-in-selective-serotonin-reuptake-inhibitor-treated-patients-with-major-depression
#1
Kadri Andre, Olli Kampman, Merja Viikki, Eija Setälä-Soikkeli, Ari Illi, Nina Mononen, Terho Lehtimäki, Esa Leinonen
OBJECTIVE: We investigated the separate effects of and possible interactions between the functional polymorphisms of brain-derived neurotrophic factor (BDNF) rs11030101, BDNF rs61888800, and neuregulin-1 (NRG1) rs3924999 and NRG1 rs6994992 on change of temperament scores in a clinical sample of subjects with major depression (MDD), who received selective serotonin reuptake inhibitor treatment for a period of 6 weeks. METHODS: The study population consisted of 98 Finnish individuals with MDD...
January 9, 2018: Acta Neuropsychiatrica
https://www.readbyqxmd.com/read/29304427/longitudinal-associations-of-temperament-and-character-with-paranoid-ideation-a-population-based-study
#2
Aino Saarinen, Tom Rosenström, Mirka Hintsanen, Christian Hakulinen, Laura Pulkki-Råback, Terho Lehtimäki, Olli T Raitakari, Claude Robert Cloninger, Liisa Keltikangas-Järvinen
The aim of this study was to examine (a) the associations of temperament and character dimensions with paranoid ideation over a 15-year follow-up in the general population (b) the associations of explosive temperament and organized character profiles with paranoid ideation. 2137 subjects of the Young Finns Study completed the Temperament and Character Inventory and the Paranoid Ideation Scale of the Symptom Checklist-90 Revised in 1997, 2001, and 2012. Temperament dimensions of high novelty seeking, high harm avoidance, low reward dependence and explosive temperament profile were associated with the development of higher paranoid ideation...
December 21, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29286553/the-relationship-between-anxious-temperament-and-harm-avoidance-in-medical-students-and-staffs
#3
Masanao Shirahama, Takeshi Terao, Nobuyoshi Ishii, Koji Hatano, Hirofumi Hirakawa, Kentaro Kohno
AIMS: In order to resolve the equivocal relationship between anxious temperament rated by the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Auto-questionnaire (TEMPS-A) and harm avoidance rated by the Temperament and Character Inventory (TCI), the present study aims to investigate whether the anxious temperament scale and the harm avoidance scale are significantly associated with adjustment of relevant factors. Our hypothesis is that anxious temperament may be associated with harm avoidance...
December 29, 2017: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/29280393/internet-gaming-disorder-and-online-gambling-disorder-clinical-and-personality-correlates
#4
Nuria Mallorquí-Bagué, Fernando Fernández-Aranda, María Lozano-Madrid, Roser Granero, Gemma Mestre-Bach, Marta Baño, Amparo Del Pino-Gutiérrez, Mónica Gómez-Peña, Neus Aymamí, José M Menchón, Susana Jiménez-Murcia
Background and aims The recent growth of Internet use has led to an increase of potentially problematic behaviors that can be engaged online, such as online gambling or Internet gaming. The aim of this study is to better conceptualize Internet gaming disorder (IGD) by comparing it with gambling disorder (GD) patients who only gamble online (online GD). Methods A total of 288 adult patients (261 online GD and 27 IGD) completed self-reported questionnaires for exploring psychopathological symptoms, food addiction (FA), and personality traits...
December 1, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/29250141/gynostemma-pentaphyllum-is-neuroprotective-in-a-rat-model-of-cardiopulmonary-resuscitation
#5
Gerburg Keilhoff, Torben Esser, Maximilian Titze, Uwe Ebmeyer, Lorenz Schild
Asphyxial cardiac arrest (ACA)-induced ischemia results in acute and delayed neuronal cell death. The early reperfusion phase is critical for the outcome. Intervention strategies directed to this period are promising to reduce ACA/resuscitation-dependent impairments. This study focused on the evaluation of the protective potential of an extract from Gynostemma pentaphyllum (GP), a plant used in traditional medicine with antioxidative, glucose lowering and neuroprotective activities, in an ACA rat model. We tested the following parameters: i) Basic systemic parameters such as pCO2 and blood glucose value within the first 30 min post-ACA; ii) mitochondrial response by determining activities of citrate synthase, respiratory chain complexes I + III and II + III, and the composition of cardiolipin 6 and 24 h post-ACA; iii) neuronal vitality of the CA1 hippocampal region by immunohistochemistry 24 h and 7 days post-ACA; and iv) cognitive function by a novel object recognition test 7 days post-ACA...
December 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29234453/an-association-study-of-taq1a-ankk1-and-c957t-and-%C3%A2-141c-drd2-polymorphisms-in-adults-with-internet-gaming-disorder-a-pilot-study
#6
Soo-Hyun Paik, Mi Ran Choi, Su Min Kwak, Sol Hee Bang, Ji-Won Chun, Jin-Young Kim, Jihye Choi, Hyun Cho, Jo-Eun Jeong, Dai-Jin Kim
Background: Though Internet gaming disorder (IGD) is considered to share similar genetic vulnerability with substance addictions, little has been explored about the role of the genetic variants on IGD. This pilot study was designed to investigate the association of the Taq1A polymorphism of the ankyrin repeat and kinase domain containing 1 (ANKK1) gene and C957T and - 141C of the dopamine D2 receptor (DRD2) with IGD and their role on the personality and temperament traits in IGD among adult population...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29217724/correlation-of-impulsivity-with-self-harm-and-suicidal-attempt-a-community-study-of-adolescents-in-taiwan
#7
Yu-Hsin Huang, Hui-Ching Liu, Fang-Ju Tsai, Fang-Ju Sun, Kuo-Yang Huang, Yu-Ching Chiu, Yen-Hsun Huang, Yo-Ping Huang, Shen-Ing Liu
OBJECTIVES: The aim of this study was to investigate differences and similarities in risk factors for deliberate self-harm (DSH) and suicidal attempt (SA), and the role of impulsivity among a group of community adolescents. SETTING: This is a cross-sectional study conducted at high schools in Northern Taiwan. DATA AND PARTICIPANTS: We recruited grade 1 students from 14 high schools. A total of 5879 participants (mean age 16.02 years, female adolescents: 57...
December 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/29169660/reward-and-loss-anticipation-in-panic-disorder-an-fmri-study
#8
Dada Held-Poschardt, Philipp Sterzer, Florian Schlagenhauf, Corinna Pehrs, Andre Wittmann, Meline Stoy, Claudia Hägele, Brian Knutson, Andreas Heinz, Andreas Ströhle
Anticipatory anxiety and harm avoidance are essential features of panic disorder (PD) and may involve deficits in the reward system of the brain, in particular in the ventral striatum. While neuroimaging studies on PD have focused on fearful and negative affective stimulus processing, no investigations have directly addressed deficits in reward and loss anticipation. To determine whether the ventral striatum shows abnormal neural activity in PD patients during anticipation of loss or gain, an event-related functional magnetic resonance imaging experiment using a monetary incentive delay task was employed in 10 patients with PD and 10 healthy controls...
November 14, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29167323/prefrontal-cortical-specific-differences-in-behavior-and-synaptic-plasticity-between-adolescent-and-adult-mice
#9
Xanthippi Konstantoudaki, Kleanthi Chalkiadaki, Elisavet Vasileiou, Katerina Kalemaki, Domna Karagogeos, Kyriaki Sidiropoulou
Adolescence is a highly vulnerable period for the emergence of major neuropsychological disorders and is characterized by decreased cognitive control and increased risk-taking behavior and novelty seeking. The prefrontal cortex (PFC) is involved in the cognitive control of impulsive and risky behavior. Although the PFC is known to reach maturation later than other cortical areas, little information is available regarding the functional changes from adolescence to adulthood in PFC , particularly compared to other primary cortical areas...
November 22, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29161023/in-vivo-neurochemical-profile-of-selectively-bred-high-responder-and-low-responder-rats-reveals-baseline-cocaine-and-novelty-evoked-differences-in-monoaminergic-systems
#10
Omar S Mabrouk, John L Han, Jenny-Marie T Wong, Huda Akil, Robert T Kennedy, Shelly B Flagel
Relative to bred low-responder (bLR) rats, bred high-responder (bHR) rats have an exaggerated locomotor response to a novel environment, are more risk-taking, more impulsive, and more likely to exhibit compulsive drug-seeking behaviors. These phenotypic differences in addiction-related behaviors and temperament have previously been associated with differences in neurotransmitter signaling, including the mesolimbic dopamine system. In the current study, we applied advanced in vivo microdialysis sampling in the nucleus accumbens of bHRs/bLRs to assess differences in basal and stimulated neurochemical efflux more broadly...
November 21, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/29150978/mice-lacking-a-functional-nmda-receptor-exhibit-social-subordination-in-a-group-housed-environment
#11
Waka Ujita, Ayako Kohyama-Koganeya, Nozomi Endo, Toki Saito, Hiroshi Oyama
Social dominance, in which an individual asserts control over others or benefits most after social conflict, has an influence on social behaviour. However, the mechanisms mediating social dominance remain unclear. Social dominance within social groups determines the distribution of rewards such as food and access to mating partners, which can act as reinforcers. In this study, we used the water competition test to determine whether mice were dominant or subordinate. We have previously reported that mice heterozygous for a missense mutation in Grin1 (Grin1(Rgsc174) ) showed altered social behaviour, with increased locomotor activity, novelty-seeking and anxiety...
November 18, 2017: FEBS Journal
https://www.readbyqxmd.com/read/29141103/risk-profiles-of-personality-traits-for-suicidality-among-mood-disorder-patients-and-community-controls
#12
M-H Su, H-C Chen, M-L Lu, J Feng, I-M Chen, C-S Wu, S-W Chang, P-H Kuo
OBJECTIVE: To examine the associations between personality traits and suicidal ideation (SI) and attempt (SA) in mood disorder patients and community controls. METHOD: We recruited 365 bipolar, 296 major depressive disorder patients, and 315 community controls to assess their lifetime suicidality. Participants filled out self-reported personality questionnaires to collect data of personality traits, including novelty seeking (NS), harm avoidance (HA), extraversion (E), and neuroticism (N)...
November 15, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29100975/personality-measures-after-gamma-ventral-capsulotomy-in-intractable-ocd
#13
Raquel R Paiva, Marcelo C Batistuzzo, Nicole C McLaughlin, Miguel M Canteras, Maria E de Mathis, Guaraci Requena, Roseli G Shavitt, Benjamin D Greenberg, Georg Norén, Steven A Rasmussen, Hermano Tavares, Eurípedes C Miguel, Antonio C Lopes, Marcelo Q Hoexter
BACKGROUND: Neurosurgeries such as gamma ventral capsulotomy (GVC) are an option for otherwise intractable obsessive-compulsive disorder (OCD) patients. In general, clinical and neuropsychological status both improve after GVC. However, its consequences on personality traits are not well-studied. The objective of this study was to investigate personality changes after one year of GVC in intractable OCD patients. METHODS: The personality assessment was conducted using the Revised NEO Personality Inventory (NEO PI-R) and Cloninger's Temperament and Character Inventory (TCI) in 14 intractable OCD patients before and one year after GVC...
November 1, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29080410/temperament-and-character-in-patients-with-systemic-lupus-erythematosus
#14
Arash Mani, Anahita Rostami, Elham Aflaki, Parsa Ravanfar
BACKGROUND: In addition to identified neuropsychiatric characteristic of systemic lupus erythematosus (SLE), changes in personality seem to occur in patients with SLE. Even in absence of an axis I psychiatric diagnosis, personality variations play important role in general wellbeing of these patients. This study investigated personality features in patients with SLE using Temperament and Character Inventory (TCI). METHOD: In this case-control study personality features of 59 patients with confirmed diagnosis of SLE were evaluated using Persian version of TCI-125 questionnaire...
September 19, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29076354/how-do-online-sports-gambling-disorder-patients-compare-with-land-based-patients
#15
Ana Estévez, Raquel Rodríguez, Noelia Díaz, Roser Granero, Gemma Mestre-Bach, Trevor Steward, Fernando Fernández-Aranda, Neus Aymamí, Mónica Gómez-Peña, Amparo Del Pino-Gutiérrez, Marta Baño, Laura Moragas, Núria Mallorquí-Bagué, Hibai López-González, Paula Jauregui, Jaione Onaindia, Virginia Martín-Romera, José M Menchón, Susana Jiménez-Murcia
Background and aims Recent technological developments have brought about notable changes in the way people gamble. The widespread use of mobile Internet devices and gambling websites has led to a significant leap in the number of people who recreationally gamble. However, for some, gambling can turn into a psychiatric disorder resembling substance addiction. At present, there is a shortage of studies examining differences between adults with gambling disorder (GD) who exclusively make sports bets online, GD patients that are non-sports Internet gamblers, and offline gamblers...
October 27, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/29062365/comparing-the-profile-of-temperament-and-character-dimensions-in-patients-with-major-depressive-disorder-and-bipolar-mood-disorder-with-a-control-group
#16
Shahram Hajirezaei, Abolfazl Mohammadi, Mehdi Soleimani, Fatemeh Rahiminezhad, Mohammad Reza Mohammadi, C Robert Cloninger
Objective: This study was conducted to compare the profile of temperament and character dimensions in patients with major depressive disorder and bipolar mood disorder with a control group. Method: In this causal-comparative study, the population consisted of 2 clinical groups (major depressive disorder and bipolar mood disorder) and a non-clinical group. The sample was 193 individuals (77 patients with major depressive disorder, 86 patients with bipolar mood disorder, and 30 controls), with an age range of 18 to 65 years and the mean age of 40...
July 2017: Iranian Journal of Psychiatry
https://www.readbyqxmd.com/read/29059106/personality-disorder-and-treatment-outcome-in-alcohol-use-disorder
#17
Giles Newton-Howes, James Foulds
PURPOSE OF REVIEW: As personality disorder impacts the outcome of most major mental disorders, it would be consistent for it to impact negatively on the outcome of alcohol use disorders (AUDs). This update is to provide an up-to-date overview of the recent literature examining the impact of personality disorder and personality traits on the treatment outcome of AUDs. RECENT FINDINGS: Comorbidity between personality disorder and AUD is significant and approaches 50%...
October 20, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/29053126/-effect-of-cytokine-genes-and-season-of-birth-on-personality
#18
M V Alfimova, V E Golimbet, G I Korovaitseva, T V Lezheiko, N V Kondrat'ev, M V Gabaeva
AIM: To evaluate the interaction effects of season of birth and immune system genes on the personality traits 'Novelty seeking' (NS) and 'Self-directedness' (SD). Based on results on an influence of the immune system on the brain processes, the authors hypothesized that the interaction of immune system genes and season of birth, which is relevant for immune phenotype, can contribute to the development of personality traits. MATERIAL AND METHODS: NS and SD were measured in 336 healthy volunteers, aged from 16 to 67 years, using the Temperament and Character Inventory (TCI-125)...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28983136/childhood-inhibitory-control-and-adolescent-impulsivity-and-novelty-seeking-as-differential-predictors-of-relational-and-overt-aggression
#19
Katherine Sarkisian, Carol Van Hulle, Kathryn Lemery-Chalfant, H H Goldsmith
Impulsivity is commonly conflated with novelty seeking, but these traits are conceptually independent and hold different predictive implications. Using a multi-informant, longitudinal design, we examined childhood inhibitory control, as well as adolescent impulsivity and novelty seeking, as predictors of aggression in a sample of 976 twins. Lower childhood inhibitory control and higher adolescent impulsivity predicted both overt and relational aggression in regression analyses that accounted for sex, puberty status, age, and socioeconomic status...
April 2017: Journal of Research in Personality
https://www.readbyqxmd.com/read/28971543/weight-loss-trajectories-in-bariatric-surgery-patients-and-psychopathological-correlates
#20
Amador García-Ruiz-de-Gordejuela, Zaida Agüera, Roser Granero, Trevor Steward, Asunción Llerda-Barberá, Elena López-Segura, Nuria Vilarrasa, Isabel Sanchez, Susana Jiménez-Murcia, Nuria Virgili, Rafael López-Urdiales, Mónica Montserrat-Gil de Bernabe, Pilar Garrido, Rosa Monseny, Carmen Monasterio, Neus Salord, Jordi Pujol-Gebelli, Jose M Menchón, Fernando Fernández-Aranda
This study aimed to explore the empirical trajectories of body mass index (BMI) 1 year following bariatric surgery (BS) and to identify the risk factors for each trajectory. The study included 115 patients with severe obesity who underwent BS. Assessment included metabolic variables, psychopathological and personality measures. Growth mixture modelling identified four separated trajectories for the percentage of total weight loss course shape (namely, T1 'good-fast', T2 'good', T3 'low' and T4 'low-slow')...
November 2017: European Eating Disorders Review: the Journal of the Eating Disorders Association
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