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Sugar independent risk factor

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https://www.readbyqxmd.com/read/28394363/interleukin-18-mediates-cardiac-dysfunction-induced-by-western-diet-independent-of-obesity-and-hyperglycemia-in-the-mouse
#1
S Carbone, P J H Lee, A G Mauro, E Mezzaroma, R Buzzetti, B Van Tassell, A Abbate, S Toldo
Obesity and diabetes are independent risk factors for heart failure and are associated with the consumption of diet rich in saturated fat and sugar, Western diet (WD), known to induce cardiac dysfunction in the mouse through incompletely characterized inflammatory mechanisms. We hypothesized that the detrimental cardiac effects of WD are mediated by interleukin-18 (IL-18), pro-inflammatory cytokine linked to cardiac dysfunction. C57BL/6J wild-type male mice and IL-18 knockout male mice were fed high-saturated fat and high-sugar diet for 8 weeks...
April 10, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28365271/dietary-and-lifestyle-risk-factors-associated-with-incident-kidney-stones-in-men-and-women
#2
Pietro Manuel Ferraro, Eric N Taylor, Giovanni Gambaro, Gary C Curhan
PURPOSE: Several dietary and lifestyle factors are associated with a higher risk of developing kidney stones. We estimated the population attributable fraction (PAF) and number needed to prevent (NNTP) for modifiable risk factors including body mass index (BMI), fluid intake, DASH-style diet, dietary calcium intake and intake of sugar-sweetened beverages. MATERIALS AND METHODS: We used data from the Health Professionals Follow-up Study (HPFS) and the Nurses' Health Studies (NHS) I and II cohorts...
March 29, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28364488/short-sleep-duration-is-associated-with-eating-more-carbohydrates-and-less-dietary-fat-in-mexican-american-children
#3
Suzanna M Martinez, Jeanne M Tschann, Nancy F Butte, Steve E Gregorich, Carlos Penilla, Elena Flores, Louise C Greenspan, Lauri A Pasch, Julianna Deardorff
Study Objective: Short sleep duration is a risk factor for childhood obesity. Mechanisms are unclear, but may involve selection of high carbohydrate foods. This study examined the association between estimated sleep duration and macronutrient intake as percentages of total energy among Mexican American (MA) 9-11 year olds. Methods: This cross-sectional study measured diet using two 24-hour recalls and estimated sleep duration using hip-worn accelerometry in MA children (n = 247) who were part of a cohort study...
February 1, 2017: Sleep
https://www.readbyqxmd.com/read/28280982/risk-factors-for-anastomotic-leakage-after-laparoscopic-surgery-with-the-double-stapling-technique-for-stage-0-i-rectal-carcinoma-a-subgroup-analysis-of-a-multicenter-single-arm-phase-ii-trial
#4
Keitaro Tanaka, Junji Okuda, Seiichiro Yamamoto, Masaaki Ito, Kazuhiro Sakamoto, Yukihito Kokuba, Kenichi Yoshimura, Masahiko Watanabe
PURPOSE: The aim of this study was to determine the risk factors for anastomotic leakage after laparoscopic rectal surgery. METHODS: We conducted a prospective trial involving 395 patients with stage 0/I rectal carcinoma who underwent laparoscopic low anterior resection using a double stapling technique. Data concerning variables related to patient background, tumors and surgical factors were evaluated. The outcomes with respect to anastomotic leakage were recorded, and univariate and multivariate analyses were performed to identify relevant risk factors...
March 9, 2017: Surgery Today
https://www.readbyqxmd.com/read/28280728/the-neutrophil-lymphocyte-ratio-is-associated-with-coronary-artery-calcification-in-asymptomatic-korean-males-a-cross-sectional-study
#5
Su-Hyun Nam, Sung-Goo Kang, Sang-Wook Song
Introduction. The neutrophil-lymphocyte ratio (NLR) is a significant systemic predictor of cardiovascular disease (CVD). The coronary artery calcium score (CACS) reflects coronary artery calcification and is an independent risk factor for coronary artery stenosis. In the present study, we explored the relationship between the NLR and CACS in terms of subclinical inflammation and coronary artery calcification. Materials and Methods. We evaluated males and females who did not have CVD, diabetes, high blood pressure, or high fasting blood sugar levels...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28262323/soft-drink-consumption-and-gestational-diabetes-risk-in-the-sun-project
#6
Mikel Donazar-Ezcurra, Cristina Lopez-Del Burgo, Miguel A Martinez-Gonzalez, Francisco J Basterra-Gortari, Jokin de Irala, Maira Bes-Rastrollo
BACKGROUND & AIMS: Gestational diabetes mellitus (GDM) prevalence is increasing worldwide. To the best of our knowledge the specific evaluation of soft drink consumption as a risk factor for developing GDM has only been conducted in the Nurses' Health Study II. OBJECTIVE: To investigate the incidence of GDM according to soft drink consumption in the SUN project. DESIGN: The "Seguimiento Universidad de Navarra" (SUN) project is a prospective and dynamic cohort which included data of 3396 women who notified at least one pregnancy between December 1999 and March 2012...
February 20, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28222484/overweight-obese-underweight-and-frequency-of-sugar-consumption-as-risk-indicators-for-early-childhood-caries-in-brazilian-preschool-children
#7
Cecilia Claudia Costa Ribeiro, Mariana Carvalho Batista da Silva, Ana Margarida Melo Nunes, Erika Bárbara de Abreu Fonseca Thomaz, Cadidja Dayane Sousa Carmo, Marizélia Rodrigues Costa Ribeiro, Antônio Augusto Moura da Silva
BACKGROUND: A possible association between being overweight or obese and early childhood caries (ECC) remains controversial. AIM: To investigated this association in a developing country testing the confounding effects of socioeconomic factors and frequency of sugar consumption. METHODS: Historical cohort study, 388 children (aged 24-71 months) living in São Luís, Brazil. A theoretical model adjusted according to income, birthweight, and nutritional status at twelve months and frequency of sugar consumption was generated with directed acyclic graphs to analyze this association...
February 21, 2017: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/28220959/evaluating-clinical-dietary-and-psychological-risk-factors-for-relapse-of-ulcerative-colitis-in-clinical-endoscopic-and-histological-remission
#8
Rajan Dhingra, Saurabh Kedia, Pratap Mouli Venigalla, Sushil Kumar, Namrata Singh, Sawan Bopanna, Vikas Singla, Bikash Narayan Choudhury, Prashant Verma, Veena Tiwari, Siddhartha Datta Gupta, Govind Makharia, Vineet Ahuja
BACKGROUND: The literature on possible factors that could trigger a relapse in patients with ulcerative colitis (UC) in clinical, endoscopic and histological remission on long term follow up is scarce. AIM: To determine the relapse rate in patients with UC in clinical, endoscopic and histological remission and identify factors that may influence the risk of relapse. METHODS: Patients with UC in clinical, endoscopic and histological remission were enrolled between January-July 2010 and followed up for 1 year to determine the effect of clinical, dietary and psychological factors on relapse...
February 21, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28214853/chronic-consumption-of-artificial-sweetener-in-packets-or-tablets-and-type-2-diabetes-risk-evidence-from-the-e3n-european-prospective-investigation-into-cancer-and-nutrition-study
#9
Guy Fagherazzi, Gaëlle Gusto, Aurélie Affret, Francesca Romana Mancini, Courtney Dow, Beverley Balkau, Françoise Clavel-Chapelon, Fabrice Bonnet, Marie-Christine Boutron-Ruault
BACKGROUND: The influence of artificial sweeteners on metabolic diseases is controversial. Artificially sweetened beverages have been associated with an increased risk of type 2 diabetes (T2D) but biases and reverse causation have been suspected to have influenced the observed association. In addition, it has been suggested that investigation into the relationship between the frequency and duration of the consumption of packet or tablet artificial sweeteners and T2D risk is necessary...
2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28161146/dietary-strategies-for-cardiovascular-health
#10
REVIEW
Brad P Dieter, Katherine R Tuttle
Cardiovascular disease is developed across a lifetime accumulation of risk. Numerous independent and synergistic cardiovascular risk factors can be induced by unhealthy dietary patterns. Epidemiological, mechanistic, clinical, and translational research point to refined sugars, processed and fatty meats, synthetic oils, and sodium as major dietary risk factors. The purpose of this review is to integrate these learnings into key principles for dietary frameworks aimed at improving overall cardiovascular health...
December 31, 2016: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28160762/dietary-therapy-in-patients-with-inflammatory-arthritis
#11
Rauli Mäkelä, Heli Mäkilä, Ritva Peltomaa
Context • The exact etiology of rheumatoid disease is currently unknown. Changes in the microbiota of the gastrointestinal (GI) tract, chronic bacterial infection of the upper urinary tract, increased permeability of the GI tract, and food sensitivities have been classified among the factors that may cause or aggravate the disease. Dietary deficiencies also may render patients more susceptible to inflammatory conditions and disorders of the immunological system. Objective • The study intended to determine the effects of a therapy consisting of dietary elimination, dietary supplements, and probiotics, collectively called DDP therapy, which is given either independently or in combination with conventional pharmacological agents...
January 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28074617/soft-drink-intake-and-the-risk-of-metabolic-syndrome-a%C3%A2-systematic-review-and-meta-analysis
#12
REVIEW
Aditya Narain, Chun Shing Kwok, Mamas A Mamas
BACKGROUND: It is unclear whether consumption of sugar- or artificially sweetened beverages is independently associated with the development of metabolic syndrome. A systematic review and meta-analysis was performed to evaluate whether soft drink consumption is associated with the development of metabolic syndrome. METHODS: Medline and EMBASE were searched in November 2015 for studies which considered soft drink (sugar-sweetened beverage [SSB] and artificially sweetened beverage [ASB]) intake and risk of metabolic syndrome...
February 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28039031/worsening-of-memory-deficit-induced-by-energy-dense-diet-in-a-rat-model-of-early-alzheimer-s-disease-is-associated-to-neurotoxic-a%C3%AE-species-and-independent-of-neuroinflammation
#13
Pamela V Martino Adami, Pablo Galeano, Marina L Wallinger, Celia Quijano, Alejandro Rabossi, Eleonora S Pagano, Natividad Olivar, Carlos Reyes Toso, Daniel Cardinali, Luis I Brusco, Sonia Do Carmo, Rafael Radi, Goar Gevorkian, Eduardo M Castaño, A Claudio Cuello, Laura Morelli
Diet is a modifiable risk factor for Alzheimer's disease (AD), but the mechanisms linking alterations in peripheral metabolism and cognition remain unclear. Since it is especially difficult to study long-term effects of high-energy diet in individuals at risk for AD, we addressed this question by using the McGill-R-Thy1-APP transgenic rat model (Tg(+/-)) that mimics presymptomatic AD. Wild-type and Tg(+/-) rats were exposed during 6months to a standard diet or a Western diet (WD), high in saturated fat and sugar...
March 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28003201/effects-of-free-sugars-on-blood-pressure-and-lipids-a-systematic-review-and-meta-analysis-of-nutritional-isoenergetic-intervention-trials
#14
Elena Fattore, Francesca Botta, Carlo Agostoni, Cristina Bosetti
BACKGROUND: Sugar has been suggested as a central risk factor in the development of noncommunicable diseases. OBJECTIVE: We assessed the evidence of the effects of free sugars compared with complex carbohydrates on selected cardiovascular disease risk factors. DESIGN: We conducted a systematic review and meta-analysis of intervention trials to compare diets that provide a given amount of energy from free sugars with a control diet that provides the same amount of energy from complex carbohydrates...
January 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27998425/-prevalence-of-nonalcoholic-fatty-liver-disease-and-its-correlated-risk-factors-in-health-population-in-guangzhou
#15
H Ge, J Chen, Y M Sun, W H Ling
Objective: To investigate the situation and its risk factors of nonalcoholic fatty liver (NAFLD) in health population, and to provide the scientific evidence for this disease control and prevention. Methods: The subjects who had health examination in our hospital from Jan 2014 to Jan 2015 were enrolled in this cross-sectional survey study. The medical history, body examination data (height, weight and blood pressure), biochemical data (blood lipid, blood sugar, liver function, etc.) and the ultrasound examination result were recorded...
December 13, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27886383/permanent-tooth-loss-and-sugar-sweetened-beverage-intake-in-u-s-young-adults
#16
Sunkyung Kim, Sohyun Park, Mei Lin
OBJECTIVE: In young adults, sugar-sweetened beverage (SSB) intake is associated with dental caries, which in turn is a major contributor to tooth loss. The independent role of SSB intake on tooth loss, however, has not been well-described. This cross-sectional study examined associations between tooth loss and SSB intake among U.S. young adults. METHODS: The outcome was number of permanent teeth lost because of dental caries or periodontal disease (0, 1-5, ≥6 teeth)...
November 25, 2016: Journal of Public Health Dentistry
https://www.readbyqxmd.com/read/27855750/short-sleep-duration-is-associated-with-eating-more-carbohydrates-and-less-dietary-fat-in-mexican-american-children
#17
Suzanna M Martinez, Jeanne M Tschann, Nancy F Butte, Steve E Gregorich, Carlos Penilla, Elena Flores, Louise C Greenspan, Lauri A Pasch, Julianna Deardorff
STUDY OBJECTIVE: Short sleep duration is a risk factor for childhood obesity. Mechanisms are unclear, but may involve selection of high carbohydrate foods. This study examined the association between estimated sleep duration and macronutrient intake as percentages of total energy among Mexican American (MA) 9-11 year olds. METHODS: This cross-sectional study measured diet using two 24-hour recalls and estimated sleep duration using hip-worn accelerometry in MA children (n=247) who were part of a cohort study...
November 14, 2016: Sleep
https://www.readbyqxmd.com/read/27790472/arterial-stiffness-and-trace-elements-in-apparently-healthy-population-a-cross-sectional-study
#18
Gangapatnam Subrahmanyam, Rama Mohan Pathapati, Krishnan Ramalingam, Selvam Armugam Indira, Katari Kantha, Bhemasen Soren
INTRODUCTION: Stiffening of arteries is a natural ageing process. Any diseases/disorders or risk factors that escalate oxidative stress, microvascular inflammation and endothelial damage may promote to premature vascular stiffening. Any imbalance in these trace element levels may independently contribute to the changes in the components in the arterial wall and thus, arterial stiffness via one or more mechanisms. AIM: To evaluate the severity of arterial stiffness in apparently healthy population and also to evaluate role of various risk factors and trace elements in the severity of arterial stiffness...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27761024/eating-disinhibition-and-vagal-tone-moderate-the-postprandial-response-to-glycemic-load-a-randomised-controlled-trial
#19
Hayley A Young, Heather Watkins
Reducing the glycemic load (GL) of the diet may benefit appetite control but its utility is complicated by psychological influences on eating. Disinhibited behaviour, a risk factor for overconsumption, is characterized by reduced prefrontal cortex activity, which in turn modulates vagal tone; a phenomenon associated with glucoregulation. This double blind randomised controlled trial explored for the first time the influence of disinhibited eating and vagal tone (heart rate variability (HRV)) on hunger and the postprandial response to GL...
October 20, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27754193/me-03-2-high-salt-intake-as-a-cause-of-obesity
#20
Graham MacGregor
High salt intake is the major cause of raised blood pressure and accordingly leads to cardiovascular diseases. Recently, it has been shown that high salt intake is associated with an increased risk of obesity through sugar-sweetened beverage consumption. Increasing evidence also suggests a direct link. Our study aimed to determine whether there was a direct association between salt intake and obesity independent of energy intake. We analyzed the data from the rolling cross-sectional study-the UK National Diet and Nutrition Survey 2008/2009 to 2011/2012...
September 2016: Journal of Hypertension
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