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Sugar independent risk factor

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https://www.readbyqxmd.com/read/29151317/prevalence-and-risk-factors-for-helicobacter-pylori-infection-in-southwest-china-a-study-of-health-examination-participants-based-on-13c-urea-breath-test
#1
Jie Liu, Yonghong Wang, Qinghua Zhao, Rong Luo, Mingzhao Xiao, Mingjun Zhang, Weibo Xie
Background/aim: Helicobacter pylori (H. pylori) has a high prevalence in developing countries. We aimed to investigate the current prevalence of H. pylori, as well as its potential serum risk factors, in a population from southwest China.Materials and methods: This cross-sectional study included 10,912 subjects who received medical examinations at the First Affiliated Hospital of Chongqing Medical University in 2014. Data regarding physical examinations and biochemical measurements were collected, and H. pylori infection was diagnosed with a 13C-urea breath test...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29147957/mobilization-of-endothelial-progenitor-cell-in-patients-with-acute-ischemic-stroke
#2
Yushuang Deng, Jian Wang, Guiqiong He, Fei Qu, Min Zheng
Endothelial progenitor cells (EPCs) have important effect in tissue repair in ischemic organs. The present study was conducted to demonstrate the mobilization of EPCs and its possible mechanism after acute ischemic stroke (AIS). A total of 148 individuals were examined, including 106 patients with ischemic stroke and 42 healthy controls. Seventy-one patients with imaging-confirmed AIS were examined at days 1, 7, 14, and 21 after stroke onset. Circulating EPCs were quantified by flow cytometry using CD133 and KDR surface markers...
November 16, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29098321/sugar-sweetened-beverage-intake-associations-with-fasting-glucose-and-insulin-concentrations-are-not-modified-by-selected-genetic-variants-in-a-chrebp-fgf21-pathway-a-meta-analysis
#3
Nicola M McKeown, Hassan S Dashti, Jiantao Ma, Danielle E Haslam, Jessica C Kiefte-de Jong, Caren E Smith, Toshiko Tanaka, Mariaelisa Graff, Rozenn N Lemaitre, Denis Rybin, Emily Sonestedt, Alexis C Frazier-Wood, Dennis O Mook-Kanamori, Yanping Li, Carol A Wang, Elisabeth T M Leermakers, Vera Mikkilä, Kristin L Young, Kenneth J Mukamal, L Adrienne Cupples, Christina-Alexandra Schulz, Tzu-An Chen, Ruifang Li-Gao, Tao Huang, Wendy H Oddy, Olli Raitakari, Kenneth Rice, James B Meigs, Ulrika Ericson, Lyn M Steffen, Frits R Rosendaal, Albert Hofman, Mika Kähönen, Bruce M Psaty, Louise Brunkwall, Andre G Uitterlinden, Jorma Viikari, David S Siscovick, Ilkka Seppälä, Kari E North, Dariush Mozaffarian, Josée Dupuis, Marju Orho-Melander, Stephen S Rich, Renée de Mutsert, Lu Qi, Craig E Pennell, Oscar H Franco, Terho Lehtimäki, Mark A Herman
AIMS/HYPOTHESIS: Sugar-sweetened beverages (SSBs) are a major dietary contributor to fructose intake. A molecular pathway involving the carbohydrate responsive element-binding protein (ChREBP) and the metabolic hormone fibroblast growth factor 21 (FGF21) may influence sugar metabolism and, thereby, contribute to fructose-induced metabolic disease. We hypothesise that common variants in 11 genes involved in fructose metabolism and the ChREBP-FGF21 pathway may interact with SSB intake to exacerbate positive associations between higher SSB intake and glycaemic traits...
November 2, 2017: Diabetologia
https://www.readbyqxmd.com/read/29081768/diet-environments-and-gut-microbiota-a-preliminary-investigation-in-children-living-in-rural-and-urban-burkina-faso-and-italy
#4
Carlotta De Filippo, Monica Di Paola, Matteo Ramazzotti, Davide Albanese, Giuseppe Pieraccini, Elena Banci, Franco Miglietta, Duccio Cavalieri, Paolo Lionetti
Diet is one of the main factors that affects the composition of gut microbiota. When people move from a rural environment to urban areas, and experience improved socio-economic conditions, they are often exposed to a "globalized" Western type diet. Here, we present preliminary observations on the metagenomic scale of microbial changes in small groups of African children belonging to the same ethnicity and living in different environments, compared to children living on the urban area of Florence (Italy). We analyzed dietary habits and, by pyrosequencing of the 16S rRNA gene, gut microbiota profiles from fecal samples of children living in a rural village of Burkina Faso (n = 11), of two groups of children living in different urban settings (Nanoro town, n = 8; Ouagadougou, the capital city, n = 5) and of a group of Italian children (n = 13)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29074008/risk-factors-for-progression-of-diabetic-retinopathy-in-alberta-first-nations-communities
#5
Christopher J Rudnisky, Beatrice K Wong, Hakique Virani, Matthew T S Tennant
OBJECTIVE: The Screening for Limb, I-Eye, Cardiovascular, and Kidney Complications (SLICK) Program was implemented in 1999 to improve diabetic care for Alberta First Nations individuals living on reserve. The purpose of this review is to determine the rate and predictors of progression of diabetic retinopathy (DR) over a 10-year period. DESIGN: Cohort study. PARTICIPANTS: Nine hundred and eighty First Nations patients with diabetes that underwent at least 2 teleophthalmology examinations during the study period...
November 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/29070436/western-diet-increases-cardiac-ceramide-content-in-healthy-and-hypertrophied-hearts
#6
T J Butler, D Ashford, A-M Seymour
BACKGROUND AND AIMS: Obesity and cardiac left ventricular hypertrophy (LVH) are recognised independent risk factors in the development of heart failure (HF). However, the combination of these factors may exacerbate the onset of cardiovascular disease by mechanisms as yet unclear. LVH leads to significant cellular remodelling, including alterations in metabolism which may result in an inappropriate accumulation of lipids and eventual lipotoxicity and apoptosis. The aim of the study was to determine the impact of dietary manipulation on cardiac metabolism in the obese and hypertrophied heart...
September 7, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29062342/prevalence-severity-and-factors-associated-with-peripheral-neuropathy-among-newly-diagnosed-diabetic-patients-attending-mulago-hospital-a-cross-sectional-study
#7
Twaha Kisozi, Edris Mutebi, Musubire Kisekka, Samden Lhatoo, Martha Sajatovic, Mark Kaddumukasa, Fredrick Nelson Nakwagala, Elly Katabira
AIMS: To determine the prevalence and associated risk factors of diabetic peripheral neuropathy (DPN) among newly diagnosed diabetes mellitus patients in Mulago Hospital. METHODS: A cross-sectional study was conducted among 248 newly diagnosed adult diabetic patients. Using the standard Neuropathy Symptom Score (NSS) and Neuropathy Disability Score (NDS) criteria, we screened them for neuropathy. Data on the socio-demographics, age, duration of symptoms and history of diabetic ulcer were analyzed using a multiple logistic regression...
June 2017: African Health Sciences
https://www.readbyqxmd.com/read/29044032/-the-relationship-between-serum-vitamin-d-levels-and-cardiovascular-risk-factors-among-icelandic-children
#8
Thorunn Hannesdottir, Hannes Hrafnkelsson, Erlingur Johannsson, Emil L Sigurdsson
OBJECTIVE: To determine the relationship between serum vitamin D levels and known cardiometabolic risk factors among healthy Icelandic children as well as study these connections independent of body mass index (BMI). METHODS: We assessed the relationship between serum 25-hydroxyvitamin D, adiposity measured as BMI and 7 cardiometabolic risk factors (high blood pressure, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, blood glucose and serum insulin)...
September 2017: Læknablađiđ
https://www.readbyqxmd.com/read/29020428/improvement-of-recalcitrant-diabetic-macular-edema-after-peritoneal-dialysis
#9
Sally S Ong, Akshay S Thomas, Sharon Fekrat
Nephropathy may be an independent and contributory risk factor for diabetic macular edema (DME). A 69-year-old man who had previously been treated with panretinal laser photocoagulation for proliferative diabetic retinopathy as well as with steroid and anti-vascular endothelial growth factor injections for DME declined additional treatment for the DME, which was worse in the right eye. The DME was observed without further treatment for the next 36 months. Despite well-controlled blood sugar, blood pressure, and lipid levels, the DME remained unchanged...
October 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28980716/metabolic-parameters-in-psoriatic-patients-treated-with-interleukin-12-23-blockade-ustekinumab
#10
Chau Yee Ng, I-Shiang Tzeng, Su-Hsun Liu, Ya-Ching Chang, Yu-Huei Huang
The associations between psoriasis, metabolic syndrome and cardiovascular events are increasingly recognized. Studies have shown decreased cardiovascular events with the treatment of methotrexate and anti-tumor necrosis factor, however, effects of interleukin (IL)-12/23 blockade remain debatable. Our study investigated the effect of IL-12/23 blockade on the metabolic parameters in patients with psoriasis. We performed a retrospective cohort study to assess 93 consecutive patients with moderate to severe plaque type psoriasis who received IL-12/23 blockade (ustekinumab) for 24 weeks between January 2012 and May 2016...
October 5, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28956423/influence-of-glucose-metabolism-on-cognitive-function-of-patients-with-acute-small-artery-occlusion
#11
L P Zhai, X L Zhang, Q B Guan, B Yu, Y P Wang, H P Shen, X X Yu, D D Wang, Y Zhu
The aim of this study was to evaluate the influence of abnormal glucose metabolism on cognitive function of patients with acute small-arterial occlusion (SAO). The present study included 1,211 patients, with small-artery occlusion according to the Trial of Org 10172 in acute stroke treatment (TOAST) classification, admitted between March 2014 and December 2016 to The Second Hospital of Jiaxing. According to cognitive function, the patients were divided into a group of normal cognitive function, a mild cognitive impairment group (MCI group) and a dementia group...
July 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28904456/association-of-serum-25-hydroxyvitamin-d-in-carotid-intima-media-thickness-a-study-from-south-india
#12
Jaydip Ray Chauduri, K Rukmini Mridula, Matapathi Umamashesh, Banda Balaraju, V C S Srinivasarao Bandaru
BACKGROUND: Abnormal carotid intima-media thickness (IMT) is a marker of carotid atherosclerosis which is a risk factor for cerebrovascular and cardiovascular diseases. Recent studies have found an association of 25-hydroxyvitamin D deficiency with abnormal carotid IMT. PURPOSE: The purpose of the study was to investigate the association of serum 25-hydroxyvitamin D levels with carotid IMT in Indian participants. MATERIALS AND METHODS: We prospectively recruited 300 participants at Yashoda Hospital, Hyderabad, during the study period between January 2012 and December 2014...
July 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/28892990/prevalence-of-acanthosis-nigricans-and-related-factors-in-iranian-obese-children
#13
Fatemeh Sayarifard, Azadeh Sayarifard, Bahar Allahverdi, Sara Ipakchi, Mastaneh Moghtaderi, Bahareh Yaghmaei
INTRODUCTION: Recognition of Acanthosis nigricans (AN) provides important opportunities for screening of obesity syndrome, dyslipidemia, hypertension and insulin resistance with diabetes mellitus 2. Considering the high prevalence of obesity among Iranian children, we designed this study to estimate the prevalence of AN and related laboratory factors in Iranian obese children. MATERIALS AND METHODS: Seventy-one obese children were enrolled in this study. Diagnosis of AN was done by clinical examination...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28860032/dietary-patterns-and-long-term-survival-a-retrospective-study-of-healthy-primary-care-patients
#14
Nilay S Shah, David Leonard, Carrie E Finley, Fatima Rodriguez, Ashish Sarraju, Carolyn E Barlow, Laura F DeFina, Benjamin L Willis, William L Haskell, David J Maron
BACKGROUND: Dietary patterns are related to mortality in selected populations with comorbidities. We studied whether dietary patterns are associated with long-term survival in a middle-aged, healthy population. METHODS: In this observational cohort study at the Cooper Clinic preventive medicine center (Dallas, Texas), a volunteer sample of 11,376 men and women with no history of myocardial infarction or stroke completed a baseline dietary assessment between 1987-1999 and were observed for an average of 18 years...
August 28, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28857035/two-common-variants-of-human-papillomavirus-type-16-e6-differentially-deregulate-sugar-metabolism-and-hypoxia-signalling-in-permissive-human-keratinocytes
#15
Sean Cuninghame, Robert Jackson, Simon J Lees, Ingeborg Zehbe
Human papillomavirus type 16 (HPV16) is responsible for most cancers attributable to HPV infection and naturally occurring variants of the HPV16 E6 oncoprotein predispose individuals to varying risk for developing cancer. Population studies by us and others have demonstrated that the common Asian-American E6 (AAE6) variant is a higher risk factor for cervical cancer than the E6 of another common variant, the European prototype (EPE6). However, a complete understanding of the molecular processes fundamental to these epidemiological findings is still lacking...
September 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28855463/the-development-of-a-pre-dehydration-check-sheet-for-independent-community-dwelling-elderly-a-continuation-of-research-about-pre-dehydration-among-elderly-individuals-who-had-been-admitted-to-or-regularly-visited-an-elderly-care-institution
#16
Hideki Taniguchi, Keiko Ushigome
AIM: In the present study, we defined the state of pre-dehydration (PD) as the suspected loss of body fluids, not accompanied by subjective symptoms (serum osmotic pressure: 292-300 mOsm/kg・H2O). The goal of this study was to develop a non-invasive PD check sheet for independent home care for the elderly. METHODS: We evaluated the serum osmotic pressure of 222 independent community dwelling elderly individuals who were >65 years of age. We then determined the association between the serum osmotic pressure and various dehydration-related diagnostic factors that we identified in a previous study...
2017: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/28759394/impact-of-prolonged-breastfeeding-on-dental-caries-a-population-based-birth-cohort-study
#17
Karen Glazer Peres, Gustavo G Nascimento, Marco Aurelio Peres, Murthy N Mittinty, Flavio Fernando Demarco, Ina Silva Santos, Alicia Matijasevich, Aluisio J D Barros
BACKGROUND: Few studies have assessed the effect of breastfeeding, bottle feeding, and sugar consumption on children's dental caries. We investigated whether the duration of breastfeeding is a risk factor for dental caries in the primary dentition, independently of sugar consumption. METHODS: An oral health study (n = 1303) nested in a birth cohort study was carried out in southern Brazil. The average number of decayed, missing, and filled primary tooth surfaces (dmfs) and severe early childhood caries (S-ECC: dmfs ≥6) were investigated at age 5 years...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28661446/olive-polyphenols-and-the-metabolic-syndrome
#18
REVIEW
Bandhita Saibandith, Jeremy P E Spencer, Ian R Rowland, Daniel M Commane
Here, the effects of consuming polyphenol-rich olive products, including olive leaves, their crude extract, and extra virgin olive oil, on aspects of the metabolic syndrome are reviewed. We have sought to summarize the available scientific evidence from dietary intervention trials demonstrating a role for these phytochemicals in ameliorating aberrant glucose metabolism, high blood pressure and elevated blood lipids, and we discuss the potential mechanisms underpinning these observations. Searches for relevant literature published in English were conducted via PubMed and Science Direct...
June 29, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28510998/new-onset-type-2-diabetes-mellitus-among-patients-receiving-hiv-care-at-newlands-clinic-harare-zimbabwe-retrospective-cohort-analysis
#19
Cleophas Chimbetete, Catrina Mugglin, Tinei Shamu, Bindu Kalesan, Barbara Bertisch, Matthias Egger, Olivia Keiser
OBJECTIVE: To assess the incidence and associated factors of Type 2 Diabetes Mellitus (T2DM) among people living with HIV (PLHIV) in Zimbabwe. METHODS: We analysed data of all HIV-infected patients older than 16 years who attended Newlands Clinic between March 1, 2004 and April 29, 2015. The clinic considers patients whose random blood sugar is higher than 11.1 mmol/l and which is confirmed by a fasting blood sugar higher than 7.0 mmol/l to have T2DM. T2DM is also diagnosed in symptomatic patients who have a RBS >11...
July 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28483048/the-association-between-diabetes-mellitus-sugar-sweetened-beverages-and-tooth-loss-in-adults-evidence-from-18-states
#20
R Constance Wiener, Chan Shen, Patricia A Findley, Usha Sambamoorthi, Xi Tan
BACKGROUND: Sugar-sweetened beverages (SSBs) are dietary sources of sugar that are factors in caries development and tooth loss. Dietary sugar also is linked to diabetes mellitus (DM). There is limited research related to SSBs and tooth loss in people with DM. The authors investigated the association between SSBs and tooth loss as it related to the presence or absence of DM. METHODS: The authors used a cross-sectional design with data reported by adults (18 years and older) who responded to the 2012 Behavior Risk Factor Surveillance System questionnaire, which was used in 18 states (N = 95,897; 14,043 who had DM and 81,854 who did not have DM)...
July 2017: Journal of the American Dental Association
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