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https://www.readbyqxmd.com/read/27884716/therapeutic-effects-of-traditionalchinesemedicineniubeixiaohe-in-mouse-tuberculosis-models
#1
Yan Liang, Xiaomei Wang, Jinying Song, Lan Wang, Dan Chen, Yourong Yang, Xuejuan Bai, Jie Wang, Yingchang Shi, Shibing Chen, Jun Liu, Cunwei Yang, Huafeng Luo, Guangling Liu, Xueqiong Wu
ETHNOPHARMACOLOGICAL RELEVANCE: The traditional Chinese medicine Niubeixiaohe (NBXH) is an effective anti-tuberculosis prescription, which is made up of Bulbus Fritillariae Cirrhosae, Rhizoma Bletillae, Radix Platycodonis, Fructus Arctii, Herba Houttuyniae and Glutinous rice. In this study, NBXH powder (I) and three kinds of NBXH extracts (II, III, and IV) were prepared. The water decoction of NBXH had been used to treat TB in clinic sixteen years suggested that it was effective to treat TB...
November 21, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27861739/afzelin-ameliorates-d-galactosamine-and-lipopolysaccharide-induced-fulminant-hepatic-failure-by-modulating-mitochondrial-quality-control-and-dynamics-150-150
#2
Sang-Bin Lee, Jung-Woo Kang, So-Jin Kim, Jongmin Ahn, Jinwoong Kim, Sun-Mee Lee
BACKGROUND AND PURPOSE: Fulminant hepatic failure (FHF) is a fatal clinical syndrome that results in excessive inflammation and hepatocyte death. Mitochondrial dysfunction is considered to be a possible mechanism of FHF. Afzelin, a flavonol glycoside found in Houttuynia cordata Thunberg, has anti-inflammatory and antioxidant properties. The present study elucidated the cytoprotective mechanisms of afzelin against D-galactosamine (GalN)/lipopolysaccharide (LPS)-induced FHF, particularly focusing on mitochondrial quality control and dynamics...
November 15, 2016: British Journal of Pharmacology
https://www.readbyqxmd.com/read/27835846/soil-amendments-effects-on-radiocesium-translocation-in-forest-soils
#3
Yuki Sugiura, Hajime Ozawa, Mitsutoshi Umemura, Chisato Takenaka
We conducted an experiment to investigate the potential of phytoremediation by soil amendments in a forest area. To desorb radiocesium ((137)Cs) from variable charges in the soil, ammonium sulfate (NH4(+)) and elemental sulfur (S) (which decrease soil pH) were applied to forest soil collected from contaminated area at a rate of 40 and 80 g/m(2), respectively. A control condition with no soil treatment was also considered. We defined four groups of aboveground conditions: planted with Quercus serrata, planted with Houttuynia cordata, covered with rice straw as litter, and unplanted/uncovered (control)...
December 2016: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/27731817/gc-ms-analyses-of-the-volatiles-of-houttuynia-cordata-thunb
#4
Zhan-Nan Yang, Shi-Qiong Luo, Jing Ma, Dan Wu, Liang Hong, Zheng-Wen Yu
GC-MS is the basis of analysis of plant volatiles. Several protocols employed for the assay have resulted in inconsistent results in the literature. We developed a GC-MS method, which were applied to analyze 25 volatiles (α-pinene, camphene, β-pinene, 2-methyl-2-pentenal, myrcene, (+)-limonene, eucalyptol, trans-2-hexenal, γ-terpinene, cis-3-hexeneyl-acetate, 1-hexanol, α-pinene oxide, cis-3-hexen-1-ol, trans-2-hexen-1-ol, decanal, linalool, acetyl-borneol, β-caryophyllene, 2-undecanone, 4-terpineol, borneol, decanol, eugenol, isophytol and phytol) of Houttuynia cordata Thunb...
September 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27698266/houttuynia-cordata-thunb-promotes-activation-of-hif-1a-foxo3-and-mef2a-pathways-to-induce-apoptosis-in-human-hepg2-hepatocellular-carcinoma-cells
#5
Jung Min Kim, In-Hu Hwang, Ik-Soon Jang, Min Kim, In Seok Bang, Soo Jung Park, Yun-Jo Chung, Jong-Cheon Joo, Min-Goo Lee
Houttuynia cordata Thunb (H cordata), a medicinal plant, has anticancer activity, as it inhibits cell growth and induces cell apoptosis in cancer. However, the potential anti-cancer activity and mechanism of H cordata for human liver cancer cells is not well understood. Recently, we identified hypoxia-inducible factor (HIF)-1A, Forkhead box (FOX)O3, and MEF2A as proapoptotic factors induced by H cordata, suggesting that HIF-1A, FOXO3, and MEF2A contribute to the apoptosis of HepG2 hepatocellular carcinoma cells...
October 3, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/27666192/effects-of-medicinal-herbs-plantago-asiatica-houttuynia-cordata-and-mentha-haplocalyx-on-non-specific-immune-responses-of-cobia-rachycentron-canadum
#6
Yu-Sheng Wu, Yin-Yu Chen, Pien-Sheng Ueng, Fan-Hua Nan
This study investigated the effects of orally administered Plantago asiatica, Houttuynia cordata, and Mentha haplocalyx on the growth and nonspecific immune responses of cobia (Rachycentron canadum). The nonspecific immune parameters assessed were weight gain, feed conversion ratio, superoxide anion (O2(-)) production, superoxide dismutase (SOD) activity, phagocytic rate, phagocytic index, lysozyme activity, serum albumin and globulin, and albumin:globulin (A/G) ratio. The growth experiment indicated that 6-week dietary treatments did not significantly affect on the growth of cobia...
September 22, 2016: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/27616026/screening-study-on-the-anti-angiogenic-effects-of-traditional-chinese-medicine-part-i-heat-clearing-and-detoxicating-tcm
#7
Xiang Tu, YuanPing Deng, Jing Chen, Quan Hu, ChengShi He, James B Jordan, Sen Zhong
ETHNOPHARMACOLOGICAL RELEVANCE: Few studies have explored the anti-angiogenic effects of TCM - even more so, as it applies to cancer treatment research. Heat-clearing and detoxicating TCM is the most frequently used category in the treatment of cancerous tumors, but lacks sufficient validation studies. AIM OF THE STUDY: The present research (in our series of studies) aims to explore the anti-angiogenic effects of TCM; so we begin with heat-clearing and detoxicating TCM...
September 8, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27605841/in-vitro-anthelmintic-assessment-of-selected-phytochemicals-against-hymenolepis-diminuta-a-zoonotic-tapeworm
#8
Vijaya, Arun K Yadav
A large number of medicinal plants are used as herbal remedy for the treatment of helminthic diseases in the developing countries, however, far too little attention has been paid to assess the anthelmintic potentials of chemical compounds that are present in these plants. This study was carried out to assess the in vitro anthelmintic effects of biochanin A, ursolic acid, betulinic acid and beta-sitosterol which are the major phytochemicals of Trifolium repens, Houttuynia cordata and Lasia spinosa, the traditionally used anthelmintic plants of Northeast India...
September 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27525953/correlation-analysis-of-genetic-diversity-and-population-structure-of-houttuynia-cordata-thunb-with-regard-to-environment
#9
J Zhong, F-C Wu, P Qiu, L-J Dai
To study the levels of genetic diversity, and population structure, of Houttuynia cordata Thunb, the genetic background and relationships of populations were analyzed in terms of environmental factors. The genetic diversity and population structure of H. cordata were investigated using sequence-related amplified polymorphisms and correlation with environmental factors was analyzed using the SPSS software. Two thousand one hundred sixty-three sites were amplified from 41 pairs of primers, 1825 of which were polymorphic, and the percentage of polymorphic loci was 84...
2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27458754/itraq-based-proteomics-revealed-the-bactericidal-mechanism-of-sodium-new-houttuyfonate-against-streptococcus-pneumoniae
#10
Xiao-Yan Yang, Tianyuan Shi, Gaofei Du, Wanting Liu, Xing-Feng Yin, Xuesong Sun, Yunlong Pan, Qing-Yu He
Sodium new houttuyfonate (SNH), an addition product of active ingredient houttuynin from the plant Houttuynia cordata Thunb., inhibits a variety of bacteria, yet the mechanism by which it induces cell death has not been fully understood. In the present study, we utilized iTRAQ-based quantitative proteomics to analyze the protein alterations in Streptococcus pneumoniae in response to SNH treatment. Numerous proteins related to the production of reactive oxygen species (ROS) were found to be up-regulated by SNH, suggesting that ROS pathways may be involved as analyzed via bioinformatics...
August 17, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27413739/preventive-effects-of-houttuynia-cordata-extract-for-oral-infectious-diseases
#11
Yasuko Sekita, Keiji Murakami, Hiromichi Yumoto, Takashi Amoh, Natsumi Fujiwara, Shohei Ogata, Takashi Matsuo, Yoichiro Miyake, Yoshiki Kashiwada
Houttuynia cordata (HC) (Saururaceae) has been used internally and externally as a traditional medicine and as an herbal tea for healthcare in Japan. Our recent survey showed that HC poultice (HCP) prepared from smothering fresh leaves of HC had been frequently used for the treatment of purulent skin diseases with high effectiveness. Our experimental study also demonstrated that ethanol extract of HCP (eHCP) has antibacterial, antibiofilm, and anti-inflammatory effects against S. aureus which caused purulent skin diseases...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27343368/adeninealkylresorcinol-the-first-alkylresorcinol-tethered-with-nucleobase-from-lasiodiplodia-sp
#12
Yu-Meng Gao, Tian-Yu Sun, Min Ma, Guo-Dong Chen, Zheng-Qun Zhou, Chuan-Xi Wang, Dan Hu, Li-Guo Chen, Xin-Sheng Yao, Hao Gao
Adeninealkylresorcinol (1), an unusual alkylresorcinol with adenine-alkylresorcinol conjoined skeleton, was isolated from an endophytic fungus Lasiodiplodia sp. obtained from a traditional Chinese medicine Houttuynia cordata Thunb., together with three new biogenetically related compounds (2-4). Their structures were elucidated by comprehensive spectroscopic analysis, and the absolute configuration of 4 was determined by the modified Mosher's method and quantum chemical calculation. Among them, adeninealkylresorcinol (1) is the first alkylresorcinol tethered with nucleobase...
July 2016: Fitoterapia
https://www.readbyqxmd.com/read/27186286/houttuynia-cordata-thunb-reverses-oxaliplatin-induced-neuropathic-pain-in-rat-by-regulating-th17-treg-balance
#13
Cheng-Fu Wan, Li-Li Zheng, Yan Liu, Xue Yu
Oxaliplatin is a widely used anti-advanced colorectal cancer drug, while it could induce neuropathy. Houttuynia cordata Thunb (HCT) has a wide range of biological activities, such as anti-inflammation, anti-cancer, and immune regulation. In the present study, we investigated the effect of HCT on oxaliplatin-induced neuropathy in rat models. HCT (1000 mg/kg/day) significantly decreased the number of withdrawal responses and the withdrawal latency in oxaliplatin-treated rats. HCT could down-regulated the serum levels of Interleukin-6 (IL-6) and macrophage inflammatory protein1-α (MIP-1α) in oxaliplatin-treated rats...
2016: American Journal of Translational Research
https://www.readbyqxmd.com/read/27169181/a-review-of-traditional-medicinal-plants-from-kachin-state-northern-myanmar
#14
REVIEW
Hain Thanda Aung, Myint Myint Sein, Mya Mu Aye, Zaw Min Thu
Medicinal plants are a vital source of medication in developing countries. In Kachin State, Northern Myanmar, the people have a long history of the use of traditional plants for medicinal purposes. This article deals with the 25 most used medicinal plants in Kachin State. They are: Drynariafortunei, Tetrastigma serrulatum, Bauhinia championii, Goniothalamus cheliensis, Juglans regia, Houttuynia cordata, Osmanthus fragrans, Pothos chinensis, Tabemaemontana coronaria, Eryngiumfoetidum, Chloranthus spicatus, Peperomia pellucida, Zanthoxylum armatum, Polygonumfagopyrum, Cymbidiumfloribundum, Amomum kravanh, Coscinium fenestratum, Solanum nigrum, Gnetum parvifolium, Desmodium triquetum, Begonia augustinec, Mappianthus iodoides, Erycibe obtusifolia, Schefflera venulosa, Holarrhena antidysenterica...
March 2016: Natural Product Communications
https://www.readbyqxmd.com/read/27116401/evaluation-of-radiocesium-concentrations-in-new-leaves-of-wild-plants-two-years-after-the-fukushima-dai-ichi-nuclear-power-plant-accident
#15
Yuki Sugiura, Michihiro Shibata, Yoshimune Ogata, Hajime Ozawa, Tsutomu Kanasashi, Chisato Takenaka
Radiocesium ((137)Cs) transfer to plants immediately after the Fukushima Dai-ichi Nuclear Power Plant accident was investigated by collecting newly emerged leaf and soil samples between May 2011 and November 2012 from 20 sites in the Fukushima prefecture. Radiocesium concentrations in leaf and soil samples were measured to calculate concentration ratios (CR). Woody plants exhibited high CR values because (137)Cs deposited on stems and/or leaves were transferred to newly emerging tissues. The CR values in 2012 declined as compared to that in 2011...
August 2016: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/27023331/anti-bacterial-and-anti-inflammatory-effects-of-ethanol-extract-from-houttuynia-cordata-poultice
#16
Yasuko Sekita, Keiji Murakami, Hiromichi Yumoto, Hiroyuki Mizuguchi, Takashi Amoh, Satoshi Ogino, Takashi Matsuo, Yoichiro Miyake, Hiroyuki Fukui, Yoshiki Kashiwada
Houttuynia cordata (HC) has been commonly used as many traditional remedies in local areas of Japan. Although many pharmacological activities of HC have been reported, the mechanism underlying the effect of HC remains unknown. We conducted the interview survey in Japan to verify how HC was actually used. The interview survey revealed that HC poultice (HCP) prepared from smothering fresh leaves of HC was most frequently used for the treatment of purulent skin diseases including furuncle and carbuncle with high effectiveness...
June 2016: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/26991297/endophytic-fungus-strain-28-isolated-from-houttuynia-cordata-possesses-wide-spectrum-antifungal-activity
#17
Feng Pan, Zheng-Qiong Liu, Que Chen, Ying-Wen Xu, Kai Hou, Wei Wu
The aim of this paper is to identify and investigate an endophytic fungus (strain 28) that was isolated from Houttuynia cordata Thunb, a famous and widely-used Traditional Chinese Medicine. Based on morphological methods and a phylogenetic analysis of ITS sequences, this strain was identified as Chaetomium globosum. An antifungal activity bioassay demonstrated that the crude ethyl acetate (EtOAc) extracts of strain 28 had a wide antifungal spectrum and strong antimicrobial activity, particularly against Exserohilum turcicum (Pass...
April 2016: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/26930990/-study-on-hplc-dad-fingerprint-of-xiaoying-jiedu-decoction
#18
Ying Cai, Yu Lu, Rong-li Qiu, Chong-fa Wang, Lin Gong, Yong-zhang Ji
OBJECTIVE: Based on backtracking method, identification and quality evaluation of Xiaoying Jiedu Decoction (XYJDD) by HPLC fingerprint analysis were carried out. METHODS: HPLC-DAD fingerprint of XYJDD was conducted with Dikma Platisil ODS C18 column (250 mm x 4.6 mm, 5 µm) and gradient elution with the mobile phase consisting of acetonitrile-(0.1% phosphoric acid-0.1% triethylamine solution) at column temperature of 30 °C. On the basis of the established chromatographic pattern of XYJDD tracking backward to the corresponding crude herbal drugs in the formula and the attribution of most peaks in the XYJDD fingerprint can be figured out...
September 2015: Zhong Yao Cai, Zhongyaocai, Journal of Chinese Medicinal Materials
https://www.readbyqxmd.com/read/26925100/in-vitro-study-on-glucose-utilization-capacity-of-bioactive-fractions-of-houttuynia-cordata-in-isolated-rat-hemidiaphragm-and-its-major-phytoconstituent
#19
Manish Kumar, Satyendra K Prasad, Siva Hemalatha
Objective. The whole plant of Houttuynia cordata has been reported to have potent antihyperglycemic activity. Therefore, the present study was undertaken to investigate the glucose utilization capacity of bioactive fractions of ethanol extract of Houttuynia cordata (HC) in isolated rat hemidiaphragm. Methods. All the fractions, that is, aqueous (AQ), hexane (HEX), chloroform (CHL), and ethyl acetate (EA), obtained from ethanol extract of H. cordata were subjected to phytochemical standardization use in quercetin as a marker with the help of HPTLC...
2016: Advances in Pharmacological Sciences
https://www.readbyqxmd.com/read/26851778/evaluation-of-antiviral-activities-of-houttuynia-cordata-thunb-extract-quercetin-quercetrin-and-cinanserin-on-murine-coronavirus-and-dengue-virus-infection
#20
REVIEW
K H Chiow, M C Phoon, Thomas Putti, Benny K H Tan, Vincent T Chow
OBJECTIVE: To evaluate the in vitro activities of the ethyl acetate (EA) fraction of Houttuynia cordata (H. cordata) Thunb. (Saururaceae) and three of its constituent flavonoids (quercetin, quercitrin and rutin) against murine coronavirus and dengue virus (DENV). METHODS: The antiviral activities of various concentrations of the EA fraction of H. cordata and flavonoids were assessed using virus neutralization tests against mouse hepatitis virus (MHV) and DENV type 2 (DENV-2)...
January 2016: Asian Pacific Journal of Tropical Medicine
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