Pedro Ávila-Ribeiro, Ana Rita Lopes, Joana Martins-Martinho, Estela Nogueira, Joana Antunes, José Carlos Romeu, Ana Rita Cruz-Machado, Elsa Vieira-Sousa
CASE REPORT: A 68-year-old male treated with secukinumab for psoriatic arthritis suspended treatment for three months due to COVID pandemic. Upon secukinumab reintroduction, anorexia and weight loss ensued and four months later he had an abrupt onset of low-grade fever, fatigue, flu-like symptoms, dyspnoea and widespread inflammatory arthralgias. Laboratory investigations showed de novo anaemia, leukopenia, lymphopenia, cytocholestasis, elevated acute phase reactants, C3 complement consumption, proteinuria (1630mg/24h), active urine sediment, positive antinuclear (1:1280) and anti-double-stranded DNA (212...
2023: ARP Rheumatol