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Sle effusion exudate

James A Stefater, Dean Eliott, Leo A Kim
Purpose: To describe a case of a patient with acute systemic lupus erythematous (SLE) causing choroidal effusions and to report a novel technique for evaluation of the choroidal fluid which sheds light on effusion pathogenesis. Observations: A 37 year-old woman was referred for decreased vision, eye pain and shortness of breath. The patient had bilateral angle closure glaucoma from choroidal effusions and bilateral pleural effusions. Work-up revealed new onset acute SLE...
April 2017: American Journal of Ophthalmology Case Reports
Sonia Hammami, Fethia Bdioui, Afef Ouaz, Hichem Loghmari, Sylvia Mahjoub, Hamouda Saffar
Systemic lupus erythematous (SLE) is an auto-immune disease with multiple organ involvements that occurs mainly in young women. Literature data suggest that serositis is more frequent in late-onset SLE. However, peritoneal serositis with massive ascites is an extremely rare manifestation. We report a case of old-onset lupus peritonitis treated successfully by Hydroxychloroquine. A 77-year-old Tunisian woman was hospitalized because of massive painful ascites. Her family history did not include any autoimmune disease...
2014: Pan African Medical Journal
Amith George Jacob, Amrutha Mary George, Teny John
Pleural Disease Global Case ReportsSESSION TYPE: Global Case ReportPRESENTED ON: Tuesday, October 28, 2014 at 01:30 PM - 02:30 PMINTRODUCTION: Black pleural effusion is an extremely rare entity and is seldom encountered. Previous case reports have identified atypical infections, malignancy and hemorrhage as possible etiologies. We report a novel case of black pleural effusion secondary to rheumatoid pleurisy which preceeded the onset of arthritic symptomsCASE PRESENTATION: A 38-year-old man presented with dyspnea, tachypnea and right chest pain for 3 weeks...
October 1, 2014: Chest
Ihteshamul Haq, Michael D Sosin, Simon Wharton, Anindya Gupta
We describe the case of a 50-year-old lady admitted with a 3-week history of dyspnoea and left-sided pleuritic pain associated with pleural effusion. This common clinical picture nevertheless gave rise to a significant diagnostic challenge. The medical history included a diagnosis of thyrotoxicosis made 6 months previously that was being treated with carbimazole by her general practitioner. Key-investigation results were as follows: (1) pleural fluid was sterile and exudative, with no malignant cells, (2) erythrocyte sedimentation rate, C reactive protein and D-dimer were raised, (3) antinuclear antibody, anti-dsDNA and antihistone antibodies were newly positive, (4) imaging revealed a large left ventricular mass consistent with thrombus in the absence of evidence of a myocardial infarction...
2013: BMJ Case Reports
S Msaad, W Ketata, N Abid, N Gaddour, H Abid, M Abdennadher, L Mnif, Z Bahloul, A Ayoub
BACKGROUND: Thymic tumors are rare representing 19 % of mediastinal masses. They are associated with several parathymic conditions. The association of thymic tumors with systemic lupus erythematosus has rarely been described. OBSERVATION: We report the case of a 20-year-old woman who presented with a sero-fibrinous bilateral exudative pleural effusion operating in a context of alteration in general status. Diagnosis of systemic lupus erythematosus was made on the basis of the presence of cutaneous symptoms, pleural effusion, hematological abnormalities and strongly positive lupus serology...
December 2012: Revue de Pneumologie Clinique
Josko Mitrović, Branimir Anić, Jadranka Morović Vergles
Eosinophilic pleural effusion (EPE) is defined as exudative effusion that contains at least 10% eosinophils. The most common conditions associated with EPE are malignancy, infections, post-traumatic and post-surgical conditions, hypersensitivity, systemic autoimmune diseases, congestive heart failure, cirrhosis, pulmonary embolus, asbestosis and drug induced EPE. Pleural effusion accompanying autoimmune diseases is most common in patients with systemic lupus erythematosus, rheumatoid arthritis, howewer it rarely occurs in patients with progressive systemic sclerosis and polymiositis...
July 2012: Lijec̆nic̆ki Vjesnik
Wei-Ting Chang, Tung-Han Hsieh, Ming-Fei Liu
Systemic lupus erythematosus (SLE) poses great difficulty in making an early diagnosis in elderly males, often presenting with atypical manifestations. Acute onset of empyematous pleural effusion has rarely been seen. Herein, we report a 66-year-old man with SLE presenting with rapid progression of bilateral pleural effusion. Diagnostic thoracocentesis disclosed neutrophil-predominant exudates and chest computed tomography revealed multiple loculated pleural effusions. Nevertheless, optimal antibiotic therapy plus surgical decortication of the pleura did not improve his condition...
April 2013: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
Eduardo Monguilhott Dalmarco, Patrícia Budni, Eduardo Benedetti Parisotto, Danilo Wilhelm Filho, Tânia Silvia Fröde
Generation of oxidative stress induced by reactive oxygen species (ROS) and nitrogen (RNS) is believed to be a primary factor in the etiology of various inflammatory diseases. Although, the process of generation of oxygen species is a physiological event, in the inflammatory process this event is increased and produces large amounts of reactive species that leads to lipid peroxidation and to cell death. Mycophenolate mofetil (MMF) is a drug effective in protecting against chronic allograft failure and recently was introduced as an alternative for the treatment of various inflammatory diseases such as glomerulopathies, systemic lupus erythematosus and systemic vasculitis...
December 2009: Transplant Immunology
Naohiko Inase, Shinichirou Tominaga, Makito Yasui, Yoshikazu Tsukada, Minoru Oukouchi, Hirotarou Miura
PURPOSE: We examined the usefulness of adenosine deaminase 2 (ADA2) in the diagnosis of tuberculous pleuritis. SUBJECTS: A hundred cases, 78 male and 22 female, with pleural effusion were examined. With regard to pleural effusion, 18 cases were transudate and 82 cases (9 tuberculous pleuritis, 27 lung cancer, 8 mesothelioma, 5 malignant diseases except lung cancer and mesothelioma, 5 benign asbestos pleurisy, 10 empyema, 10 parapneumonic effusion, one SLE, one parasitic infection, and 6 undetermined etiology) were exudates...
December 2005: Kekkaku: [Tuberculosis]
H Ideguchi, M Misumi, Y Inoue, T Ohkubo, T Tsuji, S Ohno, A Ueda, A Aoki, E Hagiwara, A Shirai, S Mizushima, M Ohno, S Nagaoka, Y Ishigatsubo
We report two cases of systemic lupus erythematosus (SLE) diagnosed when acute peritonitis was appeared. Case 1 was a 20 year-old woman suffering from stomachache and right lower abdominal pain. Case 2 was a 40 year-old woman with diarrhea, epigastralgia, pollakisuria. In both cases, their peritoneal fluids were exudative with positive autoantibodies. After high dose steroid therapy, abdominal symptoms and ascites improved promptly. However, due to the complication of lupus nephritis, additional therapy was necessary...
December 2000: Ryūmachi. [Rheumatism]
M E Carstens, L J Burgess, F J Maritz, J J Taljaard
SETTING: Tygerberg Hospital, an academic teaching hospital, Republic of South Africa. OBJECTIVE: To identify the adenosine deaminase (ADA) isoenzymes as a diagnostic tool for tuberculosis in pleural effusions with increased ADA activity. DESIGN: Patients (n = 157) with exudative effusions and ADA activities >20 U/l, due to causes which satisfied predetermined diagnostic criteria, participated in the study. They consisted of 87 tuberculous effusions, 27 infective effusions (12 empyematous and 15 non-empyematous), 37 malignant effusions and six other exudative effusions (systemic lupus erythematosus, pancreatitis and lung embolus)...
October 1998: International Journal of Tuberculosis and Lung Disease
B J Wisotsky, C B Magat-Gordon, J E Puklin
PURPOSE: To study a patient with bilateral uveal effusions and secondary glaucoma as an initial manifestation of systemic lupus erythematosus. DESIGN: A case report. METHODS: The patient presented with bilateral uveal effusions and angle-closure glaucoma. A detailed ocular examination with ultrasonography and a comprehensive medical evaluation with laboratory testing were performed. RESULTS: The ocular examination revealed bilateral uveal effusions with angle-closure and elevated intraocular pressures...
July 1998: Ophthalmology
A E Yucel, M Calguneri, S Ruacan
A 23-year-old female with systemic lupus erythematosus is reported. The clinical features included fever, shortness of breath, lymphadenopathies, hepatosplenomegaly, pleural and pericardial fluids, ANA and Anti-DNA positivity. Pleural biopsy was false positive for malignancy on two occasions. High CA125 levels were detected in both serum and pleural fluid. Following prednisolone treatment, clinical and laboratory findings returned to normal.
March 1996: Clinical Rheumatology
T Kojima, M Umeno, K Takaki, M Tanaka, T Takeda, K Nagasawa
A 19 year old female was admitted to our hospital with complaints of fever, dyspnea and chest pain. Chest x-ray film showed a massive right pleural effusion. She was diagnosed to have systemic lupus erythematosus (SLE) because of malar rash, serositis (pleuritis), positive antinuclear antibody and positive anti-DNA antibody. Then she was successfully treated with 50 mg/d prednisolone. This case was unusual and of interest in that she had eosinophilia in the peripheral blood and exudative pleural effusion and a marked elevation of serum IgE level despite no history of allergic diseases and no evidence of parasite infections...
April 1996: Fukuoka Igaku Zasshi, Hukuoka Acta Medica
H Fukuya, W Hirose, T Masuda, T Kawai, K Watanabe, M Kawagoe
A 54 year-old woman who had a 6 month history of polyarthralgias, oral ulcers, weight loss and fatigue was admitted to the Urawa Municipal Hospital. She developed high fever, dyspnea and thrombocytopenia. Chest radiograph revealed massive right pleural effusion. At this time, laboratory investigations gave the following results: hemoglobin 12.7 g/dl, WBC 7700/microliters and platelet count 9.2 x 10(4)/microliters. Antibody to DNA was negative. Antinuclear antibody was positive at a titer of 320x in a centromere pattern; Anti-RNP and anti-Sm antibodies were negative...
August 1994: Ryūmachi. [Rheumatism]
P H Schur
The complement system consists of at least 15 proteins whose sequential activation, split products, and interaction with other plasma proteins and cells are important in inflammation. Measurement of complement is useful in many rheumatic and immunologic diseases. Most attention has focused on low levels usually due to immune complex disorders. A logical starting point is measurement of the total hemolytic complement, CH50; if this is low, one can see which component is involved. If only one component concentration is decreased, an inherited defect may be present; multiple low levels usually reflect an acquired process...
April 1983: Human Pathology
B S Anikin, L P Myshentseva
No abstract text is available yet for this article.
September 1967: Terapevticheskiĭ Arkhiv
V O Mosin
No abstract text is available yet for this article.
1987: Terapevticheskiĭ Arkhiv
P H Schur
SLE is characterized by a host of immune abnormalities. It is not clear to date which of these are primary and which are secondary. The observation of a number of genetic defects suggests that they are primary. Multiple genetic defects may then lead to abnormal immune responses to common pathogens, antigens, or even autoantigens. As a result of this abnormal immune response, immune complexes form with resultant complement fixation and activation. These immune complexes interacting with cells and complement initiate an inflammatory response...
1988: Néphrologie
S Bakuła, A Wojtowicz
A case of systemic lupus erythematosus is reported in a woman aged 41 years with exudative pericarditis as the predominating manifestation of the disease. Attention is called to the diagnostic usefulness of demonstration of LE cells in pericardial effusion.
November 15, 1989: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
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