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https://www.readbyqxmd.com/read/28092318/opening-injection-pressure-is-higher-in-intraneural-compared-with-perineural-injections-during-simulated-nerve-blocks-of-the-lower-limb-in-fresh-human-cadavers
#1
Kris Vermeylen, Marlies Hermans, Filiep Soetens, Evie Vereecke, Thorsten Steinfeldt, Gerbrand Groen, Admir Hadzic, Marc Van de Velde
BACKGROUND AND OBJECTIVES: Needle-induced nerve trauma and intraneural injection can lead to neurologic injury during peripheral nerve blocks. In this study, we assessed the utility of opening injection pressure (OIP), time to OIP, and rate of rise to OIP in detecting needle-nerve contact and intraneural injection. METHODS: Five common ultrasound-guided blocks of the femoral, saphenous, subgluteal sciatic, tibial, and common peroneal nerves were simulated in 10 fresh cadavers...
January 13, 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/28078723/real-world-use-effectiveness-and-safety-of-anti-viral-treatment-in-chronic-hepatitis-c-genotype-3-infection
#2
M Cornberg, J Petersen, A Schober, S Mauss, K H W Böker, R Link, R Günther, Y Serfert, H Pfeiffer-Vornkahl, M P Manns, C Sarrazin, D Hüppe, T Berg, C Niederau
BACKGROUND: Treatment of chronic hepatitis C genotype 3 (GT3) is more challenging compared with other genotypes. Since 2014, several new treatment regimens have been approved but sometimes based on limited data. AIM: To validate the use, effectiveness and safety of anti-viral treatment in chronic hepatitis C genotype 3 infection under real-word conditions. METHODS: The German Hepatitis C-Registry is a large national non-interventional real-world study for patients with chronic hepatitis C...
January 12, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28074610/an-in%C3%A2-vitro-model-yields-importin-new-insights-into-chronic-traumatic-encephalopathy-damaged-astrocytes-stop-thrombospondin-to-the-injury-an-editorial-highlight-for-defective-synthesis-and-release-of-astrocytic-thrombospondin-1-mediates-the-neuronal-tdp-43
#3
EDITORIAL
Sausan M Jaber, Brian M Polster
Read the highlighted article 'Defective synthesis and release of astrocytic thrombospondin-1 mediates the neuronal TDP-43 proteinopathy, resulting in defects in neuronal integrity associated with chronic traumatic encephalopathy: in vitro studies' on doi: 10.1111/jnc.13867.
January 10, 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28068298/validity-of-the-agency-for-healthcare-research-and-quality-patient-safety-indicators-and-the-centers-for-medicare-and-medicaid-hospital-acquired-conditions-a-systematic-review-and-meta-analysis-by-bradford-d-winters-phd-md-aamir-bharmal-bs-mph-renee-f-wilson
#4
https://www.readbyqxmd.com/read/28062929/epidemiology-treatment-pattern-and-health-care-utilization-of-myopic-choroidal-neovascularization-a-population-based-study
#5
Ming-Chin Yang, Yen-Po Chen, Elise Chia-Hui Tan, Claudia Leteneux, Erin Chang, Carol Hy Chu, Chi-Chun Lai
PURPOSE: To investigate the prevalence and incidence of myopic choroidal neovascularization (CNV) in Taiwan, including the health care utilization and treatment-associated costs. METHODS: A retrospective cohort study using existing data from the Taiwanese National Health Insurance claims database to identify patients who had a diagnosis of myopic CNV recorded from 1 January 2009 to 31 December 2011. The prevalence of myopic CNV was monitored during this period, and the frequency and cost of both treatment visits and monitoring visits were analyzed for 2 years following diagnosis...
January 6, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28058727/exppning-how-acetylcholine-improves-gait-in-parkinson-s-disease-an-editorial-highlight-for-deletion-of-the-vesicular-acetylcholine-transporter-from-pedunculopontine-laterodorsal-tegmental-neurons-modifies-gait
#6
EDITORIAL
Björn Falkenburger
Gait impairment is one of the most intractable symptoms of Parkinson's disease, responding poorly to dopaminergic medication. Promising therapeutic strategies include deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) and enhancing cholinergic neurotransmission by acetylcholine esterase inhibitors. This Editorial discusses an elegant study by Janickova and coworkers in the current issue of the Journal of Neurochemistry, in which the authors engineered mice lacking cholinergic transmission selectively in the PPN and demonstrate that cholinergic neurons of the PPN are critical for gait...
January 6, 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28052613/retraction-reduction-of-postoperative-nausea-and-vomiting-and-analgesic-requirement-with-dexamethasone-in-women-undergoing-general-anesthesia-for-mastectomy-by-dr-yoshitaka-fujii
#7
(no author information available yet)
The Breast Journal issues a formal retraction in relation to the above article by Dr Yoshitaka Fujii. This decision was agreed upon following an investigation carried out by the University of Tsukuba in December 2012 into a substantial number of papers by Dr Fujii. This and subsequent investigations carried out by Dr Fujii's institutions under the auspices of the Japanese Society of Anesthesiologists yielded overwhelming statistical evidence of fabrication, as a result of which the above paper is being retracted...
January 2017: Breast Journal
https://www.readbyqxmd.com/read/28031170/the-influence-of-sex-on-hyperfiltration-in-patients-with-uncomplicated-type-1-diabetes
#8
Marko Škrtić, Yuliya Lytvyn, Petter Bjornstad, Heather N Reich, James W Scholey, Paul M Yip, Etienne B Sochett, Bruce A Perkins, David Z I Cherney
The aim of this analysis was to examine sex-based differences in renal segmental resistances in healthy controls (HC) and patients with type 1 diabetes (T1D). We hypothesized that hyperfiltration - an early hemodynamic abnormality associated with diabetic nephropathy (DN) - would disproportionately affect women with T1D, thereby attenuating protection against the development of renal complications. Glomerular hemodynamic parameters were evaluated in HC (n=30) and in normotensive, normoalbuminuric patients with T1D and either baseline normofiltration (n=36, T1D-N, glomerular filtration rate [GFR] 90-134 ml/min/1...
December 28, 2016: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28026862/evaluation-of-the-accuracy-of-common-weight-estimation-formulae-in-a-zambian-paediatric-surgical-population
#9
L Bowen, M Zyambo, D Snell, J Kinnear, M D Bould
Limited resources and access to healthcare in sub-Saharan Africa are associated with high rates of malnourished children, although many countries globally are demonstrating increasing childhood obesity. This study evaluated how well current age- or height-based formulae estimate the weight of children undergoing surgery in Zambia. All children under 14 years of age presenting for elective surgery at the University Teaching Hospital, Lusaka, had both height and weight measured. Their actual weight was compared against estimated weight from various formulae...
December 27, 2016: Anaesthesia
https://www.readbyqxmd.com/read/28004768/pressure-effect-on-iron-based-superconductor-lafeaso1-xhx-peculiar-response-of-1111-type-structure
#10
Kensuke Kobayashi, Jun-Ichi Yamaura, Soshi Iimura, Sachiko Maki, Hajime Sagayama, Reiji Kumai, Youichi Murakami, Hiroki Takahashi, Satoru Matsuishi, Hideo Hosono
A systematic study of the crystal structure of a layered iron oxypnictide LaFeAsO1-xHx as a function of pressure was performed using synchrotron X-ray diffraction. This compound exhibits a unique phase diagram of two superconducting phases and two parent phases. We established that the As-Fe-As angle of the FeAs4 tetrahedron widens on the application of pressure due to the interspace between the layers being nearly infilled by the large La and As atoms. Such rarely observed behaviour in iron pnictides implies that the FeAs4 coordination deviates from the regular tetrahedron in the present systems...
December 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/28000436/corrigendum-for-lu-et%C3%A2-al-2015-doi-10-1111-ele-12391
#11
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Ecology Letters
https://www.readbyqxmd.com/read/28000434/erratum-for-valdovinos-et%C3%A2-al-2016-doi-10-1111-ele-12664
#12
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Ecology Letters
https://www.readbyqxmd.com/read/27977440/bmp-use-and-the-risk-of-revision-surgery-after-long-posterolateral-fusions-in-the-elderly
#13
Varun Puvanesarajah, Amit Jain, Jourdan M Cancienne, Benjamin E Stein, Wendy M Novicoff, Adam L Shimer, Francis Shen, Hamid Hassanzadeh
STUDY DESIGN: Retrospective database review. OBJECTIVE OF THE STUDY: The objective of the study was to assess whether bone morphogenetic protein (BMP) decreases the risk of revision surgery in elderly patients treated with 3-7 level or 8 or greater level fusions. SUMMARY OF BACKGROUND DATA: Revision spine surgery in the elderly is a complex undertaking, highlighting the importance of discovering methods to decrease the risk of repeat procedures...
December 13, 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27976382/early-glycolipid-poa-in-pro-oligodendroblasts-revealed-to-be-sulfatide-an-editorial-highlight-for-sulfatide-species-with-various-fatty-acid-chains-in-oligodendrocytes-at-different-developmental-stages-determined-by-imaging-mass-spectrometry
#14
EDITORIAL
Joan M Boggs
This Editorial highlights a study by Hirahara et al. J. Neurochem. (2016) in the current issue of the Journal of Neurochemistry, in which the authors used mass spectrometry to detect sulfatide with short chain fatty acids, C16, C18, and C18:0H in pro-oligodendroblasts at embryonic stages. These findings show that sulfatide is the pro-oligodendroblast antigen(POA) glycolipid that reacts with O4 monoclonal antibody. The different sulfatide species may perform different roles during cell development and in myelin...
December 15, 2016: Journal of Neurochemistry
https://www.readbyqxmd.com/read/27976378/the-human-brain-endothelial-barrier-transcytosis-of-aav9-transduction-by-aav2-an-editorial-highlight-for-trafficking-of-adeno-associated-virus-vectors-across-a-model-of-the-blood-brain-barrier-a-comparative-study-of-transcytosis-and-transduction-using-primary
#15
EDITORIAL
Danielle Weber-Adrian, Stefan Heinen, Joseph Silburt, Zeinab Noroozian, Isabelle Aubert
Endothelial cells at the blood-brain barrier prevent the passage of adeno-associated virus 2 (AAV2) but not AAV9. This editorial highlights a study by Merkel et al. (2016) in which a barrier, composed of human brain microvascular endothelial cells in culture, was used to characterize the trafficking mechanisms leading primarily to transduction of endothelial cells for AAV2, and transcytosis for AAV9. Read the highlighted article 'Trafficking of adeno-associated virus vectors across a model of the blood-brain barrier; a comparative study of transcytosis and transduction using primary human brain endothelial cells' on doi: 10...
December 15, 2016: Journal of Neurochemistry
https://www.readbyqxmd.com/read/27938698/treatment-of-select-intrabony-defects-by-periodontal-regeneration-could-be-cost-effective-long-term-in-compliant-patients
#16
Satheesh Elangovan
Periodontal regeneration compared with access flap surgery in human intrabony defects: 20-year follow-up of a randomized clinical trial: tooth regeneration, periodontitis recurrence and costs. Cortellini P, Buti J, Prato GP, Tonetti MS.J Clin Periodontolhttp://dx.doi.org/10.1111/jcpe.12638 [Pre pub/accepted manuscript] SOURCE OF FUNDING: Nonprofit, foundations: European Research Group on Periodontology, Genova, Italy; other: Accademia Toscana di Ricerca Odontostomatologica, Florence, Italy TYPE OF STUDY/DESIGN: Randomized controlled trial...
December 2016: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/27934435/structural-and-thermodynamic-stability-of-the-1111-structure-type-a-case-study-of-the-eufznpn-series
#17
Igor V Plokhikh, Dmitri O Charkin, Valeriy Yu Verchenko, Alexey N Kuznetsov, Sergey M Kazakov, Alexander A Tsirlin, Andrei V Shevelkov
Two new compounds with the LaOAgS structure, EuFZnAs (1) and EuFZnSb (2), were obtained via solid state reaction. Both compounds are tetragonal (P4/nmm) with the cell parameters a = 4.1000(1) Å and c = 9.0811(1) Å for 1 and a = 4.2852(1)Å and c = 9.4238(1)Å for 2. The absence of their phosphide analog can be explained based on crystal chemical considerations as well as on quantum-chemical estimates of their thermodynamic stability with respect to EuF2 and EuZn2Pn2. The magnetic response of 1 and 2 is ascribed to the presence of Eu(2+) ions...
December 5, 2016: Inorganic Chemistry
https://www.readbyqxmd.com/read/27934157/photopolymerization-of-diacetylene-on-aligned-multiwall-carbon-nanotube-microfibers-for-high-performance-energy-devices
#18
Mani Ulaganathan, Reinack Varghese Hansen, Nateisha Drayton, Hardik Hingorani, R Govindan Kutty, Hrishikesh Joshi, Sivaramapanicker Sreejith, Zheng Liu, Jinglei Yang, Yanli Zhao
Linear two-dimensional materials have recently attracted an intense interest for supercapacitors because of their potential uses as electrodes in next-generation wearable electronics. However, enhancing the electrochemical properties of these materials without complicated structural modifications remains a challenge. Herein, we present the preparation of a hybrid electrode system via polydiacetylene (PDA) cloaking on the surface of aligned multiwall carbon nanotubes (MWCNTs) through self-assembly based in situ photopolymerization...
December 7, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27907062/sepsis-prevalence-and-outcome-on-the-general-wards-and-emergency-departments-in-wales-results-of-a-multi-centre-observational-point-prevalence-study
#19
Tamas Szakmany, Robert M Lundin, Ben Sharif, Gemma Ellis, Paul Morgan, Maja Kopczynska, Amrit Dhadda, Charlotte Mann, Danielle Donoghue, Sarah Rollason, Emma Brownlow, Francesca Hill, Grace Carr, Hannah Turley, James Hassall, James Lloyd, Llywela Davies, Michael Atkinson, Molly Jones, Nerys Jones, Rhodri Martin, Yousef Ibrahim, Judith E Hall
Data on sepsis prevalence on the general wards is lacking on the UK and in the developed world. We conducted a multicentre, prospective, observational study of the prevalence of patients with sepsis or severe sepsis on the general wards and Emergency Departments (ED) in Wales. During the 24-hour study period all patients with NEWS≥3 were screened for presence of 2 or more SIRS criteria. To be eligible for inclusion, patients had to have a high clinical suspicion of an infection, together with a systemic inflammatory response (sepsis) and evidence of acute organ dysfunction and/or shock (severe sepsis)...
2016: PloS One
https://www.readbyqxmd.com/read/27886365/the-use-of-ultrasound-for-peripheral-iv-placement-by-vascular-access-team-nurses-at-a-tertiary-children-s-hospital
#20
Marsha Elkhunovich, Joanna Barreras, Valerie Bock Pinero, Nurit Ziv, Aisha Vaiyani, Thomas Mailhot
PURPOSE: Children receiving treatment in the hospital frequently require intravenous (IV) access. Placement of short peripheral catheters can be painful and challenging especially in those children who have difficult access. Many children's hospitals have teams of specialized vascular access nurses experienced in peripheral catheter insertion, and at times use vein visualization devices, including ultrasound (US), to assist in peripheral IV placement. Our objectives were to describe the prevalence and success rate of US-guided peripheral IV placement by vascular access team nurses at a single tertiary children's hospital...
November 15, 2016: Journal of Vascular Access
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