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https://www.readbyqxmd.com/read/28639369/a-network-analysis-to-compare-biomarker-profiles-in-patients-with-and-without-diabetes-mellitus-in-acute-heart-failure
#1
Abhinav Sharma, Biniyam G Demissei, Jasper Tromp, Hans L Hillege, John G Cleland, Christopher M O'Connor, Marco Metra, Piotr Ponikowski, John R Teerlink, Beth A Davison, Michael M Givertz, Daniel M Bloomfield, Howard Dittrich, Dirk J van Veldhuisen, Gad Cotter, Justin A Ezekowitz, Mohsin A F Khan, Adriaan A Voors
AIMS: It is unclear whether distinct pathophysiological processes are present among patients with acute heart failure (AHF), with and without diabetes. Network analysis of biomarkers may identify correlative associations that reflect different pathophysiological pathways. METHODS AND RESULTS: We analysed a panel of 48 circulating biomarkers measured within 24 h of admission for AHF in a subset of patients enrolled in the PROTECT trial. In patients with and without diabetes, we performed a network analysis to identify correlations between measured biomarkers...
June 21, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28631087/molar-incisor-hypomineralization-proportion-and-severity-in-primary-public-school-children-in-graz-austria
#2
Barbara Buchgraber, Lumnije Kqiku, Kurt A Ebeleseder
OBJECTIVE: The aim of this study was to determine the proportion and severity of molar incisor hypomineralization (MIH) in primary school children in Graz (southeast of Austria). MATERIALS AND METHODS: In 1111 children aged 6 to 12 years (mean age 9.0 ± 1.2), a wet examination of all teeth was performed by three trained examiners using a dental chair, optimal illumination, a dental mirror, and a dental explorer. All teeth with MIH lesions were registered so that different definitions of MIH were applicable...
June 19, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28621461/the-use-of-eptifibatide-alone-or-in-combination-with-heparin-or-argatroban-for-suspected-thrombosis-in-patients-with-left-ventricular-assist-devices
#3
Abbas Bitar, Rajakrishnan Vijayakrishnan, Andrew Lenneman, Emma Birks, Todd Massey, Mark Slaughter, Dmitry Abramov
Pump thrombosis and hemolysis in patients with left ventricular assist devices (LVADs) are associated with significant morbidity and mortality. Intensification of anticoagulation has been suggested as potential therapy, with mixed results. The aim of this study is to assess the safety and efficacy of adding eptifibatide with or without an anticoagulation agent in managing patients with LVAD presenting with hemolysis and suspected pump thrombosis. This retrospective single center study included all patients who presented with their first episode of suspected pump thrombosis and were treated with eptifibatide with or without an anticoagulant between March 1, 2011 and July 30, 2015...
June 16, 2017: Artificial Organs
https://www.readbyqxmd.com/read/28618394/clinicopathological-characteristics-and-survival-outcomes-of-male-breast-cancer-according-to-race-a-seer-population-based-study
#4
He-Fen Sun, Yang Zhao, Shui-Ping Gao, Liang-Dong Li, Wen-Yan Fu, Hong-Lin Jiang, Meng-Ting Chen, Li-Peng Yang, Wei Jin
To investigate the clinicopathological characteristics and survival outcomes of breast cancer in the male population, 8,607 cases of patients were identified in the Surveillance, Epidemiology, and End Results (SEER) database, including white males (n = 7122), black males (n = 1111), and other males (American Indian/AK Native, Asian/Pacific Islander) (n = 374). Black male breast cancer patients were more likely to be in stages II-IV and have more advanced tumors. The rate of lymph node (LN) involvement at diagnosis was higher in black men than in whites and others...
May 26, 2017: Oncotarget
https://www.readbyqxmd.com/read/28594272/the-future-is-now-the-impact-of-present-fluency-in-judgments-about-the-future
#5
Tomás A Palma, Ana Sofia Santos, Leonel Garcia-Marques
Recent research has emphasised the role of episodic memory in both remembering past events and in envisaging future events. On the other hand, it has been repeatedly shown that judgments about past events are affected by the fluency with which retrieval cues are processed. In this paper we investigate whether perceptual fluency also plays a role in judgments about future events. For this purpose we conducted four experiments. The first experiment replicated recent findings showing that stimuli that are processed fluently tend to be wrongly recognised as having been encountered in the past outside the laboratory walls [Brown, A...
June 8, 2017: Memory
https://www.readbyqxmd.com/read/28581655/retracted-multilevel-predictors-of-math-classroom-climate-a-comparison-study-of-student-and-teacher-perceptions
#6
Ming-Te Wang, Jacquelynne S Eccles
The above article, published online on June 23, 2014 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor-in-Chief, Nancy Guerra, and Wiley Periodicals, Inc. The retraction has been agreed upon following the discovery that this article contained inaccurate data. It came to the author's attention that the names of some of the items reported in the Measures section of the paper could not be correct because such items did not exist in the surveys...
September 2016: Journal of Research on Adolescence: the Official Journal of the Society for Research on Adolescence
https://www.readbyqxmd.com/read/28575745/the-contrasting-microrna-content-of-a-drought-tolerant-and-a-drought-susceptible-wheat-cultivar
#7
Behnam Bakhshi, Ehsan Mohseni Fard, Javad Gharechahi, Mahdieh Safarzadeh, Nava Nikpay, Reza Fotovat, Mohammad Reza Azimi, Ghasem Hosseini Salekdeh
Drought stress represents one of the most common stresses affecting the productivity of crop plants. A rather recently discovered component of the plant response to drought is the cellular population of microRNAs. Here, the microRNA content was revealed of two bread wheat cultivars contrasting strongly with respect to the ability to withstand drought stress. A total of 1813 miRNAs was identified, grouped into 106 families. Some 104 of these miRNAs were predicted to match 212 novel miRNA precursors. In the drought tolerant cultivar (SM), 105 (33 known and 72 novel) miRNAs were altered in abundance by the imposition of drought stress, while the equivalent number in the more sensitive cultivar (SW) was 51 (20 and 31)...
May 21, 2017: Journal of Plant Physiology
https://www.readbyqxmd.com/read/28566297/effect-of-coronary-revascularization-on-the-prognostic-value-of-stress-myocardial-contrast-wall-motion-and-perfusion-imaging
#8
Nicola Gaibazzi, Thomas Porter, Valentina Lorenzoni, Gianluca Pontone, Delia De Santis, Andrea De Rosa, Andrea Igoren Guaricci
BACKGROUND: The assessment of myocardial perfusion (MP) and wall motion (WM) using contrast dipyridamole echocardiography (cSE-WMP) improves the sensitivity to detect coronary artery disease and the stratification of cardiac events, but its long-term value for fatal and nonfatal ischemic cardiac events, also with respect to patients undergoing revascularization or not, remains to be determined. METHODS AND RESULTS: One-thousand three-hundred and twenty-nine patients with suspect or known CAD who underwent cSE-WMP were followed for a median 5...
May 31, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28555779/pharmacology-of-oxidative-stress-translational-opportunities
#9
EDITORIAL
Andreas Daiber, Fabio Di Lisa, Péter Ferdinandy
This article is part of a themed section on Redox Biology and Oxidative Stress in Health and Disease. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v174.12/issuetoc.
June 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28542925/a-new-insight-into-the-ability-to-resist-ischemic-brain-injury-does-hibernation-matter-an-editorial-comment-for-arctic-ground-squirrel-hippocampus-tolerates-oxygen-glucose-deprivation-independent-of-hibernation-season-even-when-not-hibernating-and-after-atp
#10
EDITORIAL
Thomas I Nathaniel, Bianca Stewart, Jessica Williams, Michael Hood, Adebobola Imeh-Nathaniel
Read the commented article 'Arctic ground squirrel hippocampus tolerates oxygen glucose deprivation independent of hibernation season even when not hibernating and after ATP depletion, acidosis and glutamate efflux' on doi: 10.1111/jnc.13996.
July 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28526668/north-american-public-opinion-survey-on-the-acceptability-of-crowdsourcing-basic-life-support-for-out-of-hospital-cardiac-arrest-with-the-pulsepoint-mobile-phone-app
#11
Katie N Dainty, Haris Vaid, Steven C Brooks
BACKGROUND: The PulsePoint Respond app is a novel system that can be implemented in emergency dispatch centers to crowdsource basic life support (BLS) for patients with cardiac arrest and facilitate bystander cardiopulmonary resuscitation (CPR) and automated external defibrillator use while first responders are en route. OBJECTIVE: The aim of this study was to conduct a North American survey to evaluate the public perception of the above-mentioned strategy, including acceptability and willingness to respond to alerts...
May 17, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28523793/an-exercise-path-to-preventing-alzheimer-s-disease-an-editorial-highlight-on-exercise-and-bdnf-reduce-ab-production-by-enhancing-%C3%AE-secretase-processing-of-app
#12
EDITORIAL
Elizabeth J Coulson, Perry F Bartlett
Read the highlighted article 'Exercise and BDNF reduce Aβ production by enhancing α-secretase processing of APP' on page doi: 10.1111/jnc.14034.
May 18, 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28514357/-the-results-of-universal-audiological-screening-of-newborn-infants-in-the-astrakhan-region
#13
N A Daykhes, E A Grigor'eva, Yu V Nazarochkin, V M Davydov, A O Kuznetsov
We have evaluated the results of universal audiological screening of 93 352 newborn infants performed in the Astrakhan region of the Russian Federation during the period from 2009 till 2015. The screening coverage amounted to 95%. The prevalence of hearing disorders was estimated at 1:1111 and that of their severe forms at 1:3000. The clinical significance of the examination during its first stage consists of the exclusion of evoked otoacoustic emission. After the completion of the second stage, it is necessary to carry out the regular medical follow up observation of the children suffering from hearing impairment and to undertake the early rehabilitative treatment based on the application of hearing aids and prosthetic devices...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28501121/validation-of-a-field-spinal-motion-restriction-protocol-in-a-level-i-trauma-center
#14
James M Tatum, Nicolas Melo, Ara Ko, Navpreet K Dhillon, Eric J T Smith, Dorothy A Yim, Galinos Barmparas, Eric J Ley
BACKGROUND: Spinal motion restriction (SMR) after traumatic injury has been a mainstay of prehospital trauma care for more than 3 decades. Recent guidelines recommend a selective approach with cervical spine clearance in the field when criteria are met. MATERIALS AND METHODS: In January 2014, the Department of Health Services of the City of Los Angeles, California, implemented revised guidelines for cervical SMR after blunt mechanism trauma. Adult patients (aged ≥18 y) with an initial Glasgow Coma Scale (GCS) score of ≥13 presented to a single level I trauma center after blunt mechanism trauma over the following 1-y period were retrospectively reviewed...
May 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28500635/principles-of-pharmacological-research-of-nutraceuticals
#15
EDITORIAL
Ruth Andrew, Angelo A Izzo
This article is part of a themed section on Principles of Pharmacological Research of Nutraceuticals. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v174.11/issuetoc.
June 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28498994/threadomex-a-unified-platform-for-predicting-continuous-and-discontinuous-protein-domains-by-multiple-threading-and-segment-assembly
#16
Yan Wang, Jian Wang, Ruiming Li, Qiang Shi, Zhidong Xue, Yang Zhang
We develop a hierarchical pipeline, ThreaDomEx, for both continuous domain (CD) and discontinuous domain (DCD) structure predictions. Starting from a query sequence, ThreaDomEx first threads it through the PDB to identify multiple structure templates, where a profile of domain conservation score (DC-score) is derived for domain-segment assignment. To further detect DCDs that consist of separated segments along the sequence, a boundary-clustering algorithm is used to refine the DCD-linker locations. In case that the templates do not contain DCDs, a domain-segment assembly process, guided by symmetry comparison, is applied for further DCD detections...
May 11, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28486676/associations-between-self-rated-health-mental-health-problems-and-physical-inactivity-among-urban-adolescents
#17
Marketa Lachytova, Zuzana Katreniakova, Pavol Mikula, Marian Jendrichovsky, Iveta Nagyova
Self-rated health is a valid and reliable subjective indicator of general health. We aimed to assess the associations between self-rated health, mental health problems, physical activity, sedentary behaviour and BMI among Slovak urban adolescents. Data were collected within the EU-FP7: EURO-URHIS 2 (The European Health Indicator System Part 2) project in two largest Slovak cities: Bratislava and Kosice. Sample included 1111 adolescents (response rate 73.7%, mean age 14.32 ± 0.48 years, 52.8% boys). Self-rated health was measured with the first item from the Short Form Health Survey 36 questionnaire, mental health problems were assessed by the Strengths and Difficulties Questionnaire and for physical activity and sedentary behaviour questions from the WHO HBSC questionnaire were used...
May 9, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28478933/the-predictive-role-of-support-in-the-birth-experience-a-longitudinal-cohort-study
#18
Valgerdur Lisa Sigurdardottir, Jennifer Gamble, Berglind Gudmundsdottir, Hildur Kristjansdottir, Herdis Sveinsdottir, Helga Gottfredsdottir
BACKGROUND: Several risk factors for negative birth experience have been identified, but little is known regarding the influence of social and midwifery support on the birth experience over time. OBJECTIVE: The aim of this study was to describe women's birth experience up to two years after birth and to detect the predictive role of satisfaction with social and midwifery support in the birth experience. METHOD: A longitudinal cohort study was conducted with a convenience sample of pregnant women from 26 community health care centres...
May 3, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/28474800/retraction
#19
(no author information available yet)
'A meta-analysis and theoretical critique of oxytocin and psychosis: Prospects for attachment and compassion in promoting recovery' by Andrew Gumley, Christine Braehler, and Angus Macbeth (2014). The above article, published online on 21 February 2014 in Wiley Online Library (wileyonlinelibrary.com), and in Volume 53, pp. 42-61, has been retracted by agreement between the authors, the journal Editor-in-Chief, Julie Henry, and John Wiley & Sons Limited. The retraction has been agreed due to errors in the coding of effects and in the random effects components of the meta-analysis...
June 2017: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28470440/-fifteen%C3%A2-years-of-the-histopathological-synovitis-score-review-and-further-developments-of%C3%A2-a%C3%A2-diagnostic-score
#20
REVIEW
V Krenn, G Perino, W Rüther, V T Krenn, M Huber, T Hügle, A Najm, S Müller, F Boettner, F Pessler, W Waldstein, J Kriegsmann, T Häupl, S Wienert, M G Krukemeyer, S Sesselmann, R Tikhilov, L Morawietz
The histopathological synovitis score evaluates in a graded approach, as is largely usual for diagnostic histopathological scores, the immunological and inflammatory changes caused by synovitis. A synovitis score of between 1 and ≤ 4 is classified as low-grade (osteoarthritis-related synovitis, post-traumatic synovitis, meniscopathy-related synovitis and synovitis in hemochromatosis). Synovitis scores of between ≥ 5 and 9 are classified as high-grade synovitis (rheumatoid arthritis, psoriatic arthritis, Lyme's arthritis, post-infection/reactive arthritis and peripheral arthritis in Bechterew disease); sensitivity is 61...
May 3, 2017: Zeitschrift Für Rheumatologie
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