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https://www.readbyqxmd.com/read/28526668/north-american-public-opinion-survey-on-the-acceptability-of-crowdsourcing-basic-life-support-for-out-of-hospital-cardiac-arrest-with-the-pulsepoint-mobile-phone-app
#1
Katie N Dainty, Haris Vaid, Steven C Brooks
BACKGROUND: The PulsePoint Respond app is a novel system that can be implemented in emergency dispatch centers to crowdsource basic life support (BLS) for patients with cardiac arrest and facilitate bystander cardiopulmonary resuscitation (CPR) and automated external defibrillator use while first responders are en route. OBJECTIVE: The aim of this study was to conduct a North American survey to evaluate the public perception of the above-mentioned strategy, including acceptability and willingness to respond to alerts...
May 17, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28523793/an-exercise-path-to-preventing-alzheimer-s-disease-an-editorial-highlight-on-exercise-and-bdnf-reduce-ab-production-by-enhancing-%C3%AE-secretase-processing-of-app
#2
EDITORIAL
Elizabeth J Coulson, Perry F Bartlett
Read the highlighted article 'Exercise and BDNF reduce Aβ production by enhancing α-secretase processing of APP' on page doi: 10.1111/jnc.14034.
May 18, 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28514357/-the-results-of-universal-audiological-screening-of-newborn-infants-in-the-astrakhan-region
#3
N A Daykhes, E A Grigor'eva, Yu V Nazarochkin, V M Davydov, A O Kuznetsov
We have evaluated the results of universal audiological screening of 93 352 newborn infants performed in the Astrakhan region of the Russian Federation during the period from 2009 till 2015. The screening coverage amounted to 95%. The prevalence of hearing disorders was estimated at 1:1111 and that of their severe forms at 1:3000. The clinical significance of the examination during its first stage consists of the exclusion of evoked otoacoustic emission. After the completion of the second stage, it is necessary to carry out the regular medical follow up observation of the children suffering from hearing impairment and to undertake the early rehabilitative treatment based on the application of hearing aids and prosthetic devices...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28501121/validation-of-a-field-spinal-motion-restriction-protocol-in-a-level-i-trauma-center
#4
James M Tatum, Nicolas Melo, Ara Ko, Navpreet K Dhillon, Eric J T Smith, Dorothy A Yim, Galinos Barmparas, Eric J Ley
BACKGROUND: Spinal motion restriction (SMR) after traumatic injury has been a mainstay of prehospital trauma care for more than 3 decades. Recent guidelines recommend a selective approach with cervical spine clearance in the field when criteria are met. MATERIALS AND METHODS: In January 2014, the Department of Health Services of the City of Los Angeles, California, implemented revised guidelines for cervical SMR after blunt mechanism trauma. Adult patients (aged ≥18 y) with an initial Glasgow Coma Scale (GCS) score of ≥13 presented to a single level I trauma center after blunt mechanism trauma over the following 1-y period were retrospectively reviewed...
May 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28500635/principles-of-pharmacological-research-of-nutraceuticals
#5
EDITORIAL
Ruth Andrew, Angelo A Izzo
This article is part of a themed section on Principles of Pharmacological Research of Nutraceuticals. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v174.11/issuetoc.
June 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28498994/threadomex-a-unified-platform-for-predicting-continuous-and-discontinuous-protein-domains-by-multiple-threading-and-segment-assembly
#6
Yan Wang, Jian Wang, Ruiming Li, Qiang Shi, Zhidong Xue, Yang Zhang
We develop a hierarchical pipeline, ThreaDomEx, for both continuous domain (CD) and discontinuous domain (DCD) structure predictions. Starting from a query sequence, ThreaDomEx first threads it through the PDB to identify multiple structure templates, where a profile of domain conservation score (DC-score) is derived for domain-segment assignment. To further detect DCDs that consist of separated segments along the sequence, a boundary-clustering algorithm is used to refine the DCD-linker locations. In case that the templates do not contain DCDs, a domain-segment assembly process, guided by symmetry comparison, is applied for further DCD detections...
May 11, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28486676/associations-between-self-rated-health-mental-health-problems-and-physical-inactivity-among-urban-adolescents
#7
Marketa Lachytova, Zuzana Katreniakova, Pavol Mikula, Marian Jendrichovsky, Iveta Nagyova
Self-rated health is a valid and reliable subjective indicator of general health. We aimed to assess the associations between self-rated health, mental health problems, physical activity, sedentary behaviour and BMI among Slovak urban adolescents. Data were collected within the EU-FP7: EURO-URHIS 2 (The European Health Indicator System Part 2) project in two largest Slovak cities: Bratislava and Kosice. Sample included 1111 adolescents (response rate 73.7%, mean age 14.32 ± 0.48 years, 52.8% boys). Self-rated health was measured with the first item from the Short Form Health Survey 36 questionnaire, mental health problems were assessed by the Strengths and Difficulties Questionnaire and for physical activity and sedentary behaviour questions from the WHO HBSC questionnaire were used...
May 9, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28478933/the-predictive-role-of-support-in-the-birth-experience-a-longitudinal-cohort-study
#8
Valgerdur Lisa Sigurdardottir, Jennifer Gamble, Berglind Gudmundsdottir, Hildur Kristjansdottir, Herdis Sveinsdottir, Helga Gottfredsdottir
BACKGROUND: Several risk factors for negative birth experience have been identified, but little is known regarding the influence of social and midwifery support on the birth experience over time. OBJECTIVE: The aim of this study was to describe women's birth experience up to two years after birth and to detect the predictive role of satisfaction with social and midwifery support in the birth experience. METHOD: A longitudinal cohort study was conducted with a convenience sample of pregnant women from 26 community health care centres...
May 3, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/28474800/retraction
#9
(no author information available yet)
'A meta-analysis and theoretical critique of oxytocin and psychosis: Prospects for attachment and compassion in promoting recovery' by Andrew Gumley, Christine Braehler, and Angus Macbeth (2014). The above article, published online on 21 February 2014 in Wiley Online Library (wileyonlinelibrary.com), and in Volume 53, pp. 42-61, has been retracted by agreement between the authors, the journal Editor-in-Chief, Julie Henry, and John Wiley & Sons Limited. The retraction has been agreed due to errors in the coding of effects and in the random effects components of the meta-analysis...
June 2017: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28470440/-fifteen%C3%A2-years-of-the-histopathological-synovitis-score-review-and-further-developments-of%C3%A2-a%C3%A2-diagnostic-score
#10
REVIEW
V Krenn, G Perino, W Rüther, V T Krenn, M Huber, T Hügle, A Najm, S Müller, F Boettner, F Pessler, W Waldstein, J Kriegsmann, T Häupl, S Wienert, M G Krukemeyer, S Sesselmann, R Tikhilov, L Morawietz
The histopathological synovitis score evaluates in a graded approach, as is largely usual for diagnostic histopathological scores, the immunological and inflammatory changes caused by synovitis. A synovitis score of between 1 and ≤ 4 is classified as low-grade (osteoarthritis-related synovitis, post-traumatic synovitis, meniscopathy-related synovitis and synovitis in hemochromatosis). Synovitis scores of between ≥ 5 and 9 are classified as high-grade synovitis (rheumatoid arthritis, psoriatic arthritis, Lyme's arthritis, post-infection/reactive arthritis and peripheral arthritis in Bechterew disease); sensitivity is 61...
May 3, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28466193/efficacy-of-nd-yag-laser-therapy-for-the-treatment-of-verrucae-a-literature-review
#11
Vincent M Hsu, Adam S Aldahan, John P Tsatalis, Marina Perper, Keyvan Nouri
Verrucae are benign epithelial proliferations, characteristically 1-20 mm in diameter, caused by human papilloma virus (HPV) infection occurring on the skin and mucosa (Photomed Laser Surg 33(6):338-42, 2015; Lasers Med Sci 29(3):1111-6, 2014). Prevalence of verrucae is 5-20% in children and young adults with peak incidence reported during teenage years (Lasers Med Sci 29(3):1111-6, 2014; J Am Acad Dermatol 22(4):547-66, 1990; J Korean Med Sci 24(5):889-93, 2009). Patients often express significant displeasure with quality of life due to this cosmetic insecurity, as well as functional problems and physical discomfort when they occur on palms of hands and soles of feet...
May 2, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28460423/letter-to-covered-versus-uncovered-metal-stents-for-malignant-gastric-outlet-obstruction-systematic-review-and-metaanalysis-dig-endosc-doi-10-1111-den-12786
#12
Enrico Fiori, Antonietta Lamazza, Antonio V Sterpetti
We prospectively analyzed the clinical outcomes of 72 patients (2,3) and we came to similar conclusions. Conceptually, covered stents present the advantage to prevent tumor ingrowth within the stent, and, being more compliant, they could facilitate pyloric motility. However, they dislodge more easily, and distal migration of the stent can lead to serious consequences (4). This article is protected by copyright. All rights reserved.
April 29, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28451870/association-between-serum-and-synovial-fluid-dickkopf-1-levels-with-radiographic-severity-in-primary-knee-osteoarthritis-patients
#13
Theologis Thomas, Efstathopoulos Nikolaos, Nikolaou Vasileios, Charikopoulos Ioannis, Papapavlos Ioannis, Kokkoris Panayiotis, Papatheodorou Athanasios, Nasiri-Ansari Narjes, Kassi Eva
Primary knee osteoarthritis (OA) contributes to disability among middle-aged and elderly people. Dickkopf-1 (Dkk-1) and sclerostin are inhibitors of Wnt/β-catenin signaling pathway implicated in regulation of cartilage homeostasis and bone formation, respectively. We aim to investigate the association between the serum(s) and synovial fluid (SF) Dkk-1 and sclerostin levels and disease severity in patients with primary knee OA. Forty patients aged 56-87 years with primary knee OA and 20 healthy individuals were recruited...
April 27, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28447360/recent-progress-in-the-understanding-of-relaxin-family-peptides-and-their-receptors
#14
EDITORIAL
R J Summers
This article is part of a themed section on Recent Progress in the Understanding of Relaxin Family Peptides and their Receptors. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v174.10/issuetoc.
May 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28421674/retraction-statement-dynamic-complex-formation-between-hd-gyp-ggdef-and-pilz-domain-proteins-regulates-motility-in-xanthomonas-campestris
#15
(no author information available yet)
The following article from Molecular Microbiology (2012) 86(3), 557-567, 'Dynamic complex formation between HD-GYP, GGDEF and PilZ domain proteins regulates motility in Xanthomonas campestris' by Robert P. Ryan, Yvonne McCarthy, Patrick A. Kiely, Rosemary O'Connor, Chuck S. Farah, Judith P. Armitage and J. Maxwell Dow published online in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor-in-Chief, John D Helmann, and John Wiley & Sons Ltd. Since publication of the above article, it has been brought to our attention that there are several image duplications across Figures 3, 5 and 6 including duplication with another article in PNAS: 'Cell-cell signal-dependent dynamic interactions between HD-GYP and GGDEF domain proteins mediate virulence in Xanthomonas campestris', by Robert P...
May 2017: Molecular Microbiology
https://www.readbyqxmd.com/read/28418230/corrigendum-for-blonder-et%C3%A2-al-2017-doi-10-1111-ele-12736
#16
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Ecology Letters
https://www.readbyqxmd.com/read/28417467/retraction-statement-cxcl12-cxcr4-chemokine-signaling-in-spinal-glia-induces-pain-hypersensitivity-through-mapks-mediated-neuroinflammation-in-bone-cancer-rats
#17
(no author information available yet)
'CXCL12/CXCR4 chemokine signaling in spinal glia induces pain hypersensitivity through MAPKs-mediated neuroinflammation in bone cancer rats' by Hu X.-M., Liu Y.-N., Zhang H.-L., Cao S.-B., Zhang T., Chen L.-P. and Shen W. The above article from Journal of Neurochemistry, published online on 26 January 2015 and in volume 132, issue 4, pages 452-463 (available through www.onlinelibrary.wiley.com), and its subsequent Corrigendum, published online on 5 February 2015 and in volume 132, issue 4, p. 487, have been retracted by agreement between the Journal's Editor-in-Chief, Jörg Schulz, corresponding author Wen Shen on behalf of the authors, and John Wiley & Sons Ltd...
May 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28411254/safety-and-efficacy-of-romiplostim-in-splenectomized-and-nonsplenectomized-patients-with-primary-immune-thrombocytopenia
#18
Douglas B Cines, Jeffrey Wasser, Francesco Rodeghiero, Beng H Chong, Michael Steurer, Drew Provan, Roger Lyons, Jaime Garcia-Chavez, Nancy Carpenter, Xuena Wang, Melissa Eisen
Primary immune thrombocytopenia is an autoimmune disorder characterized by increased platelet destruction and insufficient platelet production without another identified underlying disorder. Splenectomy may alter responsiveness to treatment and/or increase the risk of thrombosis, infection, and pulmonary hypertension. This analysis evaluated the safety and efficacy of the thrombopoietin receptor agonist romiplostim in splenectomized and nonsplenectomized adults with primary immune thrombocytopenia. Data were pooled across 13 completed clinical studies in adults with immune thrombocytopenia from 2002-2014...
April 14, 2017: Haematologica
https://www.readbyqxmd.com/read/28403851/making-connections-across-silos-intimate-partner-violence-mental-health-and-substance-use
#19
Robin Mason, Marni Wolf, Susan O'Rinn, Gabrielle Ene
BACKGROUND: Untold numbers of women worldwide are survivors of intimate partner violence (IPV) with a substantial number of these experiencing co-occurring mental health and substance use problems. Despite the complex interconnections among these problems, funding mechanisms and organizational structures and mandates have been designed to address just a single, focal problem. One of the challenges for frontline providers is the lack of effective, evidence-informed inter-professional education or training to help them identify and appropriately respond to co-occurring problems...
April 12, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28397257/retracted-mice-lacking-the-raf-1-kinase-inhibitor-protein-exhibit-exaggerated-hypoxia-induced-pulmonary-hypertension-by-i-morecroft-b-doyle-m-nilsen-w-kolch-k-mair-and-mr-maclean-british-journal-of-pharmacology-volume-163-5-948-963-published-in-june-2011-doi
#20
(no author information available yet)
The above article, published by the British Journal of Pharmacology in June 2011 (http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01305.x/full), has been retracted by agreement between the authors, the Journal Editor in Chief and John Wiley & Sons Ltd. Formal internal investigations by the British Journal of Pharmacology have concluded that inappropriate manipulation of western blots depicted in Figures 1, 8 and 9 has occurred. The non-corresponding authors (M MacLean, B Doyle, K Mair, M Nilsen, W Kolch) wish to state that they had no knowledge that the figures in question had been manipulated...
May 2017: British Journal of Pharmacology
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