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https://www.readbyqxmd.com/read/29667361/plant-training-for-induced-defense-against-insect-pests-a-promising-tool-for-integrated-pest-management-in-cotton
#1
REVIEW
Ana L Llandres, Raki Almohamad, Thierry Brévault, Alain Renou, Idrissa Téréta, Janine Jean, François-Regis Goebel
Enhancing cotton pest management using plant natural defenses has been described as a promising way to improve the management of crop pests. We here reviewed different studies on cotton growing systems to illustrate how an ancient technique called plant training, which includes plant topping and pruning, may contribute to this goal. Based on examples from cotton crops, we show how trained plants could be promoted to a state of enhanced defense that causes faster and more robust activation of their defense responses...
April 17, 2018: Pest Management Science
https://www.readbyqxmd.com/read/29664680/steering-control-in-a-low-cost-driving-simulator-a-case-for-the-role-of-virtual-vehicle-cab
#2
Sami Mecheri, Régis Lobjois
OBJECTIVE: The aim of this study was to investigate steering control in a low-cost driving simulator with and without a virtual vehicle cab. BACKGROUND: In low-cost simulators, the lack of a vehicle cab denies driver access to vehicle width, which could affect steering control, insofar as locomotor adjustments are known to be based on action-scaled visual judgments of the environment. METHOD: Two experiments were conducted in which steering control with and without a virtual vehicle cab was investigated in a within-subject design, using cornering and straight-lane-keeping tasks...
April 1, 2018: Human Factors
https://www.readbyqxmd.com/read/29663358/a-case-control-study-of-hiv-infection-and-cancer-in-the-era-of-antiretroviral-therapy-in-rwanda
#3
Tharcisse Mpunga, Ariana Znaor, F Regis Uwizeye, Aline Uwase, Cyprien Munyanshongore, Silvia Franceschi, Gary M Clifford
The aim of our study was to assess the association between HIV infection and cancer risk in Rwanda approximately a decade after the introduction of antiretroviral therapy (cART). All persons seeking cancer care at Butaro Cancer Center of Excellence (BCCOE) in Rwanda from 2012 to 2016 were routinely screened for HIV, prior to being confirmed with or without cancer (cases and controls, respectively). Cases were coded according to ICD-O-3 and converted to ICD10. Associations between individual cancer types and HIV were estimated using adjusted unconditional logistic regression...
April 16, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29662784/clinical-translation-and-application-in-orthopaedics
#4
EDITORIAL
Chih-Hwa Chen, Regis O'Keefe
No abstract text is available yet for this article.
January 2018: Journal of Orthopaedic Translation
https://www.readbyqxmd.com/read/29662783/the-impact-of-translational-orthopaedic-research-journal-of-orthopaedic-translation-indexed-in-science-citation-index-expanded
#5
EDITORIAL
Ling Qin, Chih-Hwa Chen, Harry K Genant, Xiang-Dong Guo, Gang Li, Regis O'Keefe, R Geoff Richards, Ting-Ting Tang, Kai-Ming Chan
No abstract text is available yet for this article.
January 2018: Journal of Orthopaedic Translation
https://www.readbyqxmd.com/read/29662780/distinct-metabolic-programs-induced-by-tgf-%C3%AE-1-and-bmp2-in-human-articular-chondrocytes-with-osteoarthritis
#6
Cuicui Wang, Richard M Silverman, Jie Shen, Regis J O'Keefe
Objectives: Cellular energy metabolism is important for the function of all tissues, including cartilage. Recent studies indicate that superficial and deep subpopulations of articular chondrocytes (ACs) have distinct metabolic profiles. At the cellular and molecular level, osteoarthritis (OA) is characterised by alteration from a healthy homoeostatic state towards a catabolic state. Several molecular pathways, including transforming growth factor beta (TGF-β) and bone morphogenetic protein (BMP) signalling, have been identified as critical players in the pathogenesis and progression of OA...
January 2018: Journal of Orthopaedic Translation
https://www.readbyqxmd.com/read/29662216/cortical-drive-and-thalamic-feed-forward-inhibition-control-thalamic-output-synchrony-during-absence-seizures
#7
Cian McCafferty, François David, Marcello Venzi, Magor L Lőrincz, Francis Delicata, Zoe Atherton, Gregorio Recchia, Gergely Orban, Régis C Lambert, Giuseppe Di Giovanni, Nathalie Leresche, Vincenzo Crunelli
Behaviorally and pathologically relevant cortico-thalamo-cortical oscillations are driven by diverse interacting cell-intrinsic and synaptic processes. However, the mechanism that gives rise to the paroxysmal oscillations of absence seizures (ASs) remains unknown. Here we report that, during ASs in behaving animals, cortico-thalamic excitation drives thalamic firing by preferentially eliciting tonic rather than T-type Ca 2+ channel (T-channel)-dependent burst firing in thalamocortical (TC) neurons and by temporally framing thalamic output via feedforward reticular thalamic (NRT)-to-TC neuron inhibition...
April 16, 2018: Nature Neuroscience
https://www.readbyqxmd.com/read/29661804/combined-use-of-two-supervised-learning-algorithms-to-model-sea-turtle-behaviours-from-tri-axial-acceleration-data
#8
L Jeantet, F Dell'Amico, M A Forin-Wiart, M Coutant, M Bonola, D Etienne, J Gresser, S Regis, N Lecerf, F Lefebvre, B de Thoisy, Y Le Maho, M Brucker, N Châtelain, R Laesser, F Crenner, Y Handrich, R Wilson, D Chevallier
Accelerometers are becoming ever more important sensors in animal-attached technology, providing data that allow determination of body posture and movement and thereby helping elucidate behaviour in animals that are difficult to observe.We sought to validate the identification of sea turtle behaviours from accelerometer signals by deploying tags on the carapace of a juvenile loggerhead ( Caretta caretta ), an adult hawksbill ( Eretmochelys imbricata) and an adult green turtle ( Chelonia mydas ) at Aquarium La Rochelle...
April 16, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29660159/cannabis-and-anti-cancer-drugs-societal-usage-and-expected-pharmacological-interactions-a-review
#9
REVIEW
Régis Bouquié, Guillaume Deslandes, Hélène Mazaré, Marion Cogné, Julien Mahé, Matthieu Grégoire, Pascale Jolliet
Cannabis is a plant that has been used for centuries to relieve a wide range of symptoms. Since the 1960s, interest in medical research into this plant has grown steadily. Already very popular for recreational use, a growing number of consumers not accustomed to using cannabis for psychoactive purposes, have begun to use it as an alternative or complement to mainstream pharmaceutical medicines. The principal unsubstantiated or "social" uses of cannabis are based mainly on data that is at best controversial, but usually not scientifically proven...
April 16, 2018: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/29659712/visually-sensitive-networks-in-essential-tremor-evidence-from-structural-and-functional-imaging
#10
Constantin Tuleasca, Jean Régis, Elena Najdenovska, Tatiana Witjas, Nadine Girard, Jean-Philippe Thiran, Meritxell Bach Cuadra, Marc Levivier, Dimitri Van De Ville
No abstract text is available yet for this article.
April 12, 2018: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29656608/combined-therapy-for-critical-limb-ischemia-biomimetic-plga-microcarriers-potentiates-the-pro-angiogenic-effect-of-adipose-tissue-stromal-vascular-fraction-cells
#11
Laurence Hoareau, Florian Fouchet, Cynthia Planesse, Sophie Mirbeau, Laurence Sindji, Emmanuel Delay, Régis Roche, Claudia N Montero-Menei, Franck Festy
We propose a regenerative solution in the treatment of critical limb ischemia. Poly-lactic/glycolic acid (PLGA) microcarriers were prepared and coated with laminin to be sterilized through γ-irradiation of 25 kGy at low temperature. Stromal vascular fraction (SVF) cells were extracted through enzymatic digestion of adipose tissue. Streptozotocin-induced diabetic mice underwent arteriotomy and received an administration of SVF cells combined or not with biomimetic microcarriers. Functional evaluation of the ischemic limb was then reported and tissue reperfusion was evaluated through fluorescence molecular tomography (FMT)...
April 14, 2018: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/29655567/acute-coronary-syndrome-relationship-between-genetic-variants-and-timi-risk
#12
Viviane do Carmo Vasconcelos de Carvalho, Lílian Caroliny Amorim Silva, Romário Martins Araújo, Fábia Carla da Silva Soares, Maria José Ribeiro Bezerra, Sávio Augusto Vieira de Oliveira, Alex José de Melo Silva, Sérgio Tavares Montenegro, Roberto Pereira Werkhauser, Carlos Gustavo Régis da Silva, Adriana Vieira Gomes, Clarice Neuenschwander Lins de Morais, Silvia Maria Lucena Montenegro
Acute Coronary Syndrome (ACS) is a multifactorial disease, including the genetic factor, caused by coronary artery obstruction by atheroma. Some genetic variants have been described as risk factors for this disease. Its early diagnosis and stratification of risk of death by Thrombolysis in Myocardial Infarction (TIMI) are important. Therefore, we evaluated variants in the IL6R (c950-1722C>T), TNFa (c.-488G>A), LEPR (c.2673+1118C>T) and IL1b (c.-598T>C) genes in relation to TIMI risk, cytokine serum levels, and risk factors for ACS...
April 11, 2018: Cytokine
https://www.readbyqxmd.com/read/29651288/-cebpe-mutant-specific-granule-deficiency-correlates-with-aberrant-granule-organization-and-substantial-proteome-alterations-in-neutrophils
#13
Nina K Serwas, Jakob Huemer, Régis Dieckmann, Ester Mejstrikova, Wojciech Garncarz, Jiri Litzman, Birgit Hoeger, Ondrej Zapletal, Ales Janda, Keiryn L Bennett, Renate Kain, Dontscho Kerjaschky, Kaan Boztug
Specific granule deficiency (SGD) is a rare disorder characterized by abnormal neutrophils evidenced by reduced granules, absence of granule proteins, and atypical bilobed nuclei. Mutations in CCAAT/enhancer-binding protein-ε ( CEBPE ) are one molecular etiology of the disease. Although C/EBPε has been studied extensively, the impact of CEBPE mutations on neutrophil biology remains elusive. Here, we identified two SGD patients bearing a previously described heterozygous mutation (p.Val218Ala) in CEBPE . We took this rare opportunity to characterize SGD neutrophils in terms of granule distribution and protein content...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29650555/noninfectious-lung-complications-after-allogeneic-haematopoietic-stem-cell-transplantation
#14
Anne Bergeron, Sylvie Chevret, Régis Peffault de Latour, Karine Chagnon, Constance de Margerie-Mellon, Frédéric Rivière, Marie Robin, Jean Mani, Gwenael Lorillon, Gérard Socié, Abdellatif Tazi
Epidemiological data on late noninfectious pulmonary complications (LONIPCs) following allogeneic haematopoietic stem cell transplantation (HSCT) are derived exclusively from retrospective studies and conflicting. We aimed to evaluate prospectively their incidence, risk factors and outcomes.All consecutive patients scheduled to receive allogeneic HSCT between 2006 and 2008, at the university-teaching Saint Louis Hospital (Paris, France) were screened for inclusion. Eligible patients were those surviving at day 100...
April 12, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29644774/preparation-of-cyclobutene-acetals-and-tricyclic-oxetanes-via-photochemical-tandem-and-cascade-reactions
#15
Julien Buendia, Zong Chang, Hendrik Eijsberg, Régis Guillot, Angelo Frongia, Francesco Secci, Juan Xie, Sylvie Robin, Thomas Boddaert, David J Aitken
We describe a photochemical reaction paradigm using two starting materials, a cyclopent-2-enone and an alkene, which are transformed in a controlled manner via the initial [2+2]-photocycloaddition adducts into cyclobutene aldehydes (conveniently trapped as stable acetals) or unprecedented angular tricyclic 4:4:4 oxetane-containing skeletons. These compounds are formed via tandem or triple cascade photochemical reaction processes, respectively. Small libraries of each compound class have been prepared, suggesting that this photochemistry paradigm opens new opportunities for fine synthesis design and for widening molecular diversity...
April 12, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29642956/the-reduced-genome-of-candidatus-kinetoplastibacterium-sorsogonicusi-the-endosymbiont-of-kentomonas-sorsogonicus-trypanosomatidae-loss-of-the-haem-synthesis-pathway
#16
Flávia M Silva, Alexei Y Kostygov, Viktoria V Spodareva, Anzhelika Butenko, Regis Tossou, Julius Lukeš, Vyacheslav Yurchenko, João M P Alves
Trypanosomatids of the genera Angomonas and Strigomonas (subfamily Strigomonadinae) have long been known to contain intracellular beta-proteobacteria, which provide them with many important nutrients such as haem, essential amino acids and vitamins. Recently, Kentomonas sorsogonicus, a divergent member of Strigomonadinae, has been described. Herein, we characterize the genome of its endosymbiont, Candidatus Kinetoplastibacterium sorsogonicusi. This genome is completely syntenic with those of other known Ca...
April 12, 2018: Parasitology
https://www.readbyqxmd.com/read/29628252/processing-and-antibacterial-properties-of-chitosan-coated-alginate-fibers
#17
Mélanie Dumont, Régis Villet, Manon Guirand, Alexandra Montembault, Thierry Delair, Stéphane Lack, Michel Barikosky, Agnès Crepet, Pierre Alcouffe, Frédéric Laurent, Laurent David
The preparation of chitosan-coated alginate fibers by a wet spin process is presented and the characterization of the antibacterial activities of these fibers is discussed. Preformed calcium alginate fibers were passed in chitosan acetate solutions. The coagulation method of the coating consisted in the immersion of fibers in a bath of calcium dihydroxide solution (0.1 M). The antibacterial evaluation was achieved by a CFU (Colony-Forming Units) counting method after 6 h of incubation at 37 °C. The incorporation of chitosan on calcium alginate fibers brings antibacterial activities against Staphylococcus epidermidis, Escherichia coli and various Staphylococcus aureus strains namely MSSA (Methicillin Sensitive Staphylococcus aureus), CA-MRSA (Community Associated Methicillin Resistant Staphylococcus aureus) and HA-MRSA (Healthcare Associated Methicillin Resistant Staphylococcus aureus) which make these chitosan-coated fibers potential candidates for wound dressing materials...
June 15, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29626320/uric-acid-levels-are-associated-with-endothelial-dysfunction-and-severity-of-coronary-atherosclerosis-during-a-first-episode-of-acute-coronary-syndrome
#18
Mélanie Gaubert, Marion Marlinge, Marine Alessandrini, Marc Laine, Laurent Bonello, Julien Fromonot, Jennifer Cautela, Franck Thuny, Jeremie Barraud, Giovanna Mottola, Pascal Rossi, Emmanuel Fenouillet, Jean Ruf, Régis Guieu, Franck Paganelli
The role of serum uric acid in coronary artery disease has been extensively investigated. It was suggested that serum uric acid level (SUA) is an independent predictor of endothelial dysfunction and related to coronary artery lesions. However, the relationship between SUA and severity of coronary atherosclerosis evaluated via endothelial dysfunction using peripheral arterial tone (PAT) and the reactive hyperhemia index (RHI) has not been investigated during a first episode of acute coronary syndrome (ACS). The aim of our study was to address this point...
April 6, 2018: Purinergic Signalling
https://www.readbyqxmd.com/read/29625706/pharmaceutical-cognitive-doping-in-students-a-chimeric-way-to-get-a-head
#19
Louise Carton, Nicolas Cabé, Olivier Ménard, Sylvie Deheul, Anne-Sylvie Caous, David Devos, Olivier Cottencin, Régis Bordet
For students, the pressing demands for memorization, top-level performance, and peer competition create an environment favorable for pharmaceutical cognitive doping behavior. We aimed to describe recent practices and the benefit/risk ratio of such behavior and to discuss the issues at stake. The prevalence of pharmaceutical cognitive doping among students has been reported from 1.3% to 33% across studies, with variations depending on country and definition of pharmaceutical cognitive doping. The therapeutic classes most frequently cited as being diverted for doping purposes are psychostimulants and nootropics (methylphenidate, modafinil, piracetam), corticosteroids, sedative drugs and beta-blockers...
March 6, 2018: Thérapie
https://www.readbyqxmd.com/read/29624897/palladium-catalyzed-functionnalization-of-kraft-lignin-ether-linkages-through-the-telomerisation-reaction
#20
Clément Dumont, Régis Gauvin, Frédéric Belva, Mathieu Sauthier
Kraft lignin was efficiently functionalized with octadienyl ether linkages thanks to the palladium-catalyzed telomerisation of 1,3-butadiene. The comparison with molecular model substrates allowed to assess the grafting of phenols and alcohols and an optimization study lead to up to 69 % conversion of the total number of hydroxyl groups present in lignin. This catalytic study evidenced the partial oxidation of triphenylphosphine into triphenylphosphine oxide and triphenylphosphine sulfide by contaminants present in the industrial grade Kraft lignin...
April 6, 2018: ChemSusChem
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