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https://www.readbyqxmd.com/read/27914816/clinical-approach-used-in-medical-consultations-for-allergic-like-events-following-immunization-case-series-report-in-relation-to-practice-guidelines
#1
Joseline G Zafack, Gaston De Serres, Isabelle Rouleau, Marie-Claude Gariépy, Rémi Gagnon, Jean-Philippe Drolet, Danuta M Skowronski
BACKGROUND: The Joint Task Force on Practice Parameters (JTFPP) guidelines for the investigation and reimmunization of patients who experienced allergic-like events (ALEs) after immunization are predicated on the likelihood of anaphylaxis, assessed through the time to symptom onset (≤ or >4 hours) and number of systems involved. OBJECTIVE: The objectives of this study were to compare the management of a series of patients with ALE in actual practice relative to JTFPP guidelines and to discuss key concepts and considerations in their use...
November 30, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27914423/measurement-of-the-low-wavenumber-component-within-a-turbulent-wall-pressure-by-an-inverse-problem-of-vibration
#2
Damien Lecoq, Charles Pézerat, Fabien Chevillotte, Rémi Bessis
An experimental validation is implemented for the measurement of a weak acoustic component within a turbulent wall pressure by an inverse problem of vibration. The turbulent flow is generated by a forward-facing step in a wind tunnel. In addition to the flow, an acoustic source with a low level excites the plate and plays the role of an additional acoustic component to be identified. The inverse methods called the force analysis technique and the corrected force analysis technique are used to compute the wall pressure fluctuations from the measurement of the plate vibration using an array of 13 accelerometers...
September 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27914393/influence-of-vocal-tract-geometry-simplifications-on-the-numerical-simulation-of-vowel-sounds
#3
Marc Arnela, Saeed Dabbaghchian, Rémi Blandin, Oriol Guasch, Olov Engwall, Annemie Van Hirtum, Xavier Pelorson
For many years, the vocal tract shape has been approximated by one-dimensional (1D) area functions to study the production of voice. More recently, 3D approaches allow one to deal with the complex 3D vocal tract, although area-based 3D geometries of circular cross-section are still in use. However, little is known about the influence of performing such a simplification, and some alternatives may exist between these two extreme options. To this aim, several vocal tract geometry simplifications for vowels [ɑ], [i], and [u] are investigated in this work...
September 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27913511/treatment-of-the-elderly-patient-with-mantle-cell-lymphoma
#4
Pierre Soubeyran, Rémy Gressin
Treatment options for mantle cell lymphomas have expanded considerably over recent years, offering hematologists solutions for older patients with an appropriate risk-to-benefit ratio. Indeed, unfit older patients are exposed to a higher risk of toxicity with a standard treatment. Although new treatments have generally good safety profiles, they may lead to unexpected consequences in unfit older patients. Involving geriatricians and a comprehensive geriatric assessment in patient care could help hematologists address these vulnerabilities...
December 2, 2016: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/27913333/super-cell-piezoelectric-composite-with-1-3-connectivity
#5
Remi Rouffaud, Franck Levassort, Mai Pham Thi, Claire Bantignies, Marc Lethiecq, Anne-Christine Hladky-Hennion
The standard fabrication method for 1-3 piezocomposites for ultrasound transducers is the "dice and fill" method (DFM) in which lateral periodicity is introduced. This contributes to the appearance of spurious modes that can drastically affect the performance of the device if they appear near its thickness mode frequency, thus limiting the effective frequency range. A new 1-3 piezocomposite fabricated with a super-cell structure [1-3 super cell (13SC)] was designed in order to overcome these limitations. It consists of the merging of several periodic cells with 47% PZT volume fraction and epoxy resin as the matrix...
December 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/27911943/enhanced-in-planta-fitness-through-adaptive-mutations-in-efpr-a-dual-regulator-of-virulence-and-metabolic-functions-in-the-plant-pathogen-ralstonia-solanacearum
#6
Anthony Perrier, Rémi Peyraud, David Rengel, Xavier Barlet, Emmanuel Lucasson, Jérôme Gouzy, Nemo Peeters, Stéphane Genin, Alice Guidot
Experimental evolution of the plant pathogen Ralstonia solanacearum, where bacteria were maintained on plant lineages for more than 300 generations, revealed that several independent single mutations in the efpR gene from populations propagated on beans were associated with fitness gain on bean. In the present work, novel allelic efpR variants were isolated from populations propagated on other plant species, thus suggesting that mutations in efpR were not solely associated to a fitness gain on bean, but also on additional hosts...
December 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/27910946/ki-67-in-endometrial-cancer-scoring-optimization-and-prognostic-relevance-for-window-studies
#7
Sarah Kitson, Vanitha N Sivalingam, James Bolton, Rhona McVey, Mashid Nickkho-Amiry, Melanie E Powell, Alexandra Leary, Hans W Nijman, Remi A Nout, Tjalling Bosse, Andrew G Renehan, Henry C Kitchener, Richard J Edmondson, Emma J Crosbie
Ki-67, a marker of cellular proliferation, is increasingly being used in pre-surgical window studies in endometrial cancer as a primary outcome measure. Unlike in breast cancer, however, there are no guidelines standardizing its measurement and its clinical relevance as a response biomarker is undetermined. It is, therefore, imperative that Ki-67 scoring protocols are optimized and its association with patient survival rigorously evaluated, in order to be able to clinically interpret the results of these studies...
December 2, 2016: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/27909656/outcomes-of-demineralized-bone-matrix-enriched-with-concentrated-bone-marrow-aspirate-in-lumbar-fusion
#8
Remi M Ajiboye, Mark A Eckardt, Jason T Hamamoto, Benjamin Plotkin, Michael D Daubs, Jeffrey C Wang
BACKGROUND: Multiple studies have demonstrated that a significant amount of variability exists in various demineralized bone matrix (DBM) formulations, which casts doubts on its reliability in consistently promoting fusion. Bone marrow aspirate (BMA) is a cellular based graft that contains mesenchymal stem cells (MSCs) and growth factors can confer osteogenic and osteoinductive potential to DBM. The goal of this study was to describe the outcome of DBM enriched with concentrated BMA in patients undergoing combined lumbar interbody and posterolateral fusion...
2016: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/27909491/idiopathic-vpc-distribution-of-foci-and-tips-of-ablation
#9
REVIEW
Jose C Pachon M Md PhD, Tasso J Lobo Md, Enrique I Pachon M Md, Tomas G Santillana P Md, Carlos Tc Pachon Md, Juan C Pachon M Md, Remy N Albornoz V Md, Juan C Zerpa A Md, Felipe A Ortencio Md
Idiopathic Ventricular Premature Contraction (VPC) is currently more routinely referred for electrophysiology evaluation. Usually it carries a good prognosis but, when symptomatic or suspected to produce ventricular dysfunction, will require treatment. Nowadays, RF ablation has great advantages over antiarrhythmic drugs. Classically the outflow tract (right or left), with the typical inferior axis with left (eventually right) bundle brunch block like ECG morphology, is considered the most frequent site of origin for idiopathic VPC, but with the widespread of EP procedures and advancement of technology making possible to map and ablate difficult locations, it is possible to see a growing and changing population referred for idiopathic VPC ablation, displaying that, almost any region of the heart may be source of this kind of arrhythmia that can be successfully treated...
April 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27909050/notch-pathway-is-activated-via-genetic-and-epigenetic-alterations-and-is-a-therapeutic-target-in-clear-cell-renal-cancer
#10
Tushar D Bhagat, Yiyu Zou, Shizeng Huang, Jihwan Park, Matthew B Palmer, Caroline Hu, Wejuan Li, Niraj Shenoy, Orsolya Giricz, Gaurav Choudhary, Yiting Yu, Yi-An Ko, Maria C Izquierdo, Ae Seo Deok Park, Nishanth Vallumsetla, Remi Laurence, Robert Lopez, Masako Suzuki, James Pullman, Justin Kaner, Benjamin Gartrell, A Ari Hakimi, John M Greally, Bharvin Patel, Karim Benhadji, Kith Pradhan, Amit Verma, Katalin Susztak
Clear cell renal cell carcinoma (CCRCC) is an incurable malignancy in advanced stages and needs newer therapeutic targets. Transcriptomic analysis of CCRCCs and matched microdissected renal tubular controls revealed overexpression of NOTCH ligands and receptors in tumor tissues. Examination of the TCGA RNA-seq dataset also revealed widespread activation of NOTCH pathway in a large cohort of CCRCC samples. Samples with NOTCH pathway activation were also clinically distinct and were associated with better overall survival...
December 1, 2016: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/27906364/time-dependent-laser-linewidth-beat-note-digital-acquisition-and-numerical-analysis
#11
Nicolas Von Bandel, Mikhaël Myara, Mohamed Sellahi, Tahar Souici, Rémi Dardaillon, Philippe Signoret
We revisit and improve the optical heterodyne technique for the measurement of the laser coherence, by digital acquisition of the beat-note and numerical analysis of the resulting signal. Our main result is that with the same experimental setup we reach the very "short-time linewidth" with the highest accuracy as well as the frequency noise spectrum.
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27902225/desulfobulbus-oligotrophicus-sp-nov-a-novel-sulfate-reducing-and-propionate-oxidizing-bacterium-isolated-from-a-municipal-anaerobic-sewage-sludge-digester
#12
Abdelaziz El Houari, Magali Ranchou-Peyruse, Anthony Ranchou-Peyruse, Adrien Dakdaki, Marion Guignard, Lahcen Idouhammou, Rhizlane Bennisse, Radia Bouterfass, Rémy Guyoneaud, Abdel-Illah Qatibi
A novel, mesophilic, strictly anaerobic, sulfate-reducing and propionate-oxidizing bacterium, strain Prop6T, was enriched and isolated from a municipal anaerobic sewage sludge digester. Cells were Gram-negative, catalase-positive, oval rods, motile by means of amphitrichous flagella, non-spore-forming and contained menaquinone MK-5(H2) as the major respiratory quinone. The genomic DNA G+C content was 51.7 mol%. The optimal NaCl concentration, temperature and pH were 2-5 g l-1, 35°C and 7.6, respectively. Strain Prop6T could only oxidize propionate, lactate and pyruvate (weakly) with sulfate, sulfite or thiosulfate, mainly to acetate...
October 27, 2016: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/27901393/comparison-of-desired-radiographic-advancement-distance-and-true-advancement-distance-required-for-patellar-tendon-tibial-plateau-angle-reduction-to-the-ideal-90%C3%A2-in-dogs-by-use-of-the-modified-maquet-technique
#13
Paul Pillard, Veronique Livet, Quentin Cabon, Camille Bismuth, Juliette Sonet, Denise Remy, Didier Fau, Claude Carozzo, Eric Viguier, Thibaut Cachon
OBJECTIVE To evaluate the validity of 2 radiographic methods for measurement of the tibial tuberosity advancement distance required to achieve a reduction in patellar tendon-tibial plateau angle (PTA) to the ideal 90° in dogs by use of the modified Maquet technique (MMT). SAMPLE 24 stifle joints harvested from 12 canine cadavers. PROCEDURES Radiographs of stifle joints placed at 135° in the true lateral position were used to measure the required tibial tuberosity advancement distance with the conventional (A(M)) and correction (A(E)) methods...
December 2016: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/27894420/structural-basis-for-the-recognition-of-spliceosomal-smn-b-b-proteins-by-the-rbm5-ocre-domain-in-splicing-regulation
#14
André Mourão, Sophie Bonnal, Komal Soni, Lisa Warner, Rémy Bordonné, Juan Valcárcel, Michael Sattler
The multi-domain splicing factor RBM5 regulates the balance between antagonistic isoforms of the apoptosis-control genes FAS/CD95, Caspase-2 and AID. An OCRE (OCtamer REpeat of aromatic residues) domain found in RBM5 is important for alternative splicing regulation and mediates interactions with components of the U4/U6.U5 tri-snRNP. We show that the RBM5 OCRE domain adopts a unique β-sheet fold. NMR and biochemical experiments demonstrate that the OCRE domain directly binds to the proline-rich C-terminal tail of the essential snRNP core proteins SmN/B/B'...
November 29, 2016: ELife
https://www.readbyqxmd.com/read/27893726/glutamatergic-synaptic-integration-of-locomotion-speed-via-septoentorhinal-projections
#15
Daniel Justus, Dennis Dalügge, Stefanie Bothe, Falko Fuhrmann, Christian Hannes, Hiroshi Kaneko, Detlef Friedrichs, Liudmila Sosulina, Inna Schwarz, David Anthony Elliott, Susanne Schoch, Frank Bradke, Martin Karl Schwarz, Stefan Remy
The medial septum and diagonal band of Broca (MSDB) send glutamatergic axons to medial entorhinal cortex (MEC). We found that this pathway provides speed-correlated input to several MEC cell-types in layer 2/3. The speed signal is integrated most effectively by pyramidal cells but also excites stellate cells and interneurons. Thus, the MSDB conveys speed information that can be used by MEC neurons for spatial representation of self-location.
November 28, 2016: Nature Neuroscience
https://www.readbyqxmd.com/read/27892900/integrating-telepresence-robots-into-nursing-simulation
#16
Alexandra Rudolph, Jacqueline Vaughn, Nancy Crego, Remi Hueckel, Michele Kuszajewski, Margory Molloy, Raymond Brisson, Ryan J Shaw
This article provides an overview of the use of telepresence robots in clinical practice and describes an evaluation of an educational project in which distance-based nurse practitioner students used telepresence robots in clinical simulations with on-campus Accelerated Bachelor of Science in Nursing students. The results of this project suggest that the incorporation of telepresence in simulation is an effective method to promote engagement, satisfaction, and self-confidence in learning.
October 11, 2016: Nurse Educator
https://www.readbyqxmd.com/read/27891311/comparison-of-antibacterial-efficacy-of-coconut-oil-and-chlorhexidine-on-streptococcus-mutans-an-in-vivo-study
#17
Faizal C Peedikayil, Vimal Remy, Seena John, T P Chandru, Prathima Sreenivasan, Gufran Ahmed Bijapur
AIMS: Streptococcus mutans is the most common organism causing dental caries. Various chemotherapeutic agents are available that help in treating the bacteria, with each having their own merits and demerits. Recent research has shown that coconut oil has anti-inflammatory and antimicrobial action. Therefore, the present was conducted to determine the antibacterial efficacy of coconut oil and to compare it with chlorhexidine. MATERIALS AND METHODS: A total of fifty female children aged 8-12 years were included in the study...
September 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/27890664/do-alcohol-based-hand-rubs-reduce-the-incidence-of-acute-diarrhea-during-military-deployments-a-prospective-randomized-trial
#18
Tiphanie Succo, Franck De Laval, Sébastien Sicard, Didier Belleoud, Catherine Marimoutou, Aurélie Mayet, Luis Sagaon-Teyssier, Rémy Michel
BACKGROUND: Acute diarrhea remains a public health concern in armed forces deployed in tropical areas where access to water and soap is limited. This study aims to assess the effectiveness of alcohol-based hand rubs (ABHR) on incidence of diarrhea in poor hygiene conditions. METHOD: A prospective randomized trial was conducted between November 2014 and January 2015 among French military troops deployed in Africa to compare a group of soldiers receiving usual hand hygiene recommendations (control group), to a group of soldiers who received ABHR in addition to usual hand hygiene recommendations (intervention group)...
November 23, 2016: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/27888359/low-25-oh-vitamin%C3%A2-d-levels-reflect-hepatic-dysfunction-and-are-associated-with-mortality-in-patients-with-liver-cirrhosis
#19
Rafael Paternostro, Doris Wagner, Thomas Reiberger, Mattias Mandorfer, Remy Schwarzer, Monika Ferlitsch, Michael Trauner, Markus Peck-Radosavljevic, Arnulf Ferlitsch
BACKGROUND AND AIMS: Vitamin D deficiency is frequent in patients with cirrhosis. The aims of this study were to evaluate the relation of vitamin D status to portal hypertension, degree of liver dysfunction and survival. METHODS: Patients with cirrhosis who have been tested for 25-OH-vitamin D levels were retrospectively included. Vitamin D deficiency was defined as 25-OH-vitamin D levels <10 ng/ml. Child-Pugh score, model for end-stage liver disease (MELD) and available hepatic venous pressure gradient (HVPG) were recorded...
November 25, 2016: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/27888005/a-simplified-semi-quantitative-structural-lung-disease-computed-tomography-outcome-during-quiet-breathing-in-infants-with-cystic-fibrosis
#20
Magali Saguintaah, Yann Cabon, Rémi Gauthier, Cécile Duboibaudry, Laure Couderc, Muriel Le Bourgeois, Philippe Reix, Raphael Chiron, Ikram Taleb Arrada, Nicolas Molinari, Stefan Matecki
Chest tomography (CT) using the controlled ventilation technique (CTCV) is a sensitive method to detect features of lung cystic fibrosis (CF) disease in infants with CF. However, this technique needs sedation and is not easily applied for the clinician who may need, in the follow-up, to evaluate more precisely lung disease in infants with CF. Thus, our study aims to evaluate if CT assessment of lung disease, without the need of sedation, during quiet breathing, using a semi-quantitative scoring system, is reproducible and may discriminate infants with CF from control infants at an early stage of the lung disease...
November 22, 2016: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
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