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https://www.readbyqxmd.com/read/28724206/vital-signs-health-care-associated-legionnaires-disease-surveillance-data-from-20-states-and-a-large-metropolitan-area-united-states-2015
#1
EDITORIAL
E A Soda, A E Barskey, P P Shah, S Schrag, C G Whitney, M J Arduino, S C Reddy, J M Kunz, C M Hunter, B H Raphael, L A Cooley
BACKGROUND: Legionnaires' disease, a severe pneumonia, is typically acquired through inhalation of aerosolized water containing Legionella bacteria. Legionella can grow in the complex water systems of buildings, including health care facilities. Effective water management programs could prevent the growth of Legionella in building water systems. METHODS: Using national surveillance data, Legionnaires' disease cases were characterized from the 21 jurisdictions (20 U...
August 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28722620/case-report-infectious-diseases-in-pilgrims-visiting-the-holy-land
#2
Orna Nitzan, Arnon Blum, Esther Marva, Adina Katz, Bat-Sheva Tzadok, Yaarit Nachum-Biala, Gad Baneth, Avi Peretz
Every year Christian pilgrims from around the world visit the holy sites located around the Sea of Galilee. Some become ill during their stay with infectious diseases that were acquired in their country of origin, and are hospitalized at Poriya Medical Center. They pose a diagnostic challenge due to language barriers, the rarity of these infections in Israel, and the fact that diagnostic tests are not readily available. All patient records from 2015 of Holy Land tourists hospitalized at Poriya Medical Center were screened for the diagnosis of imported zoonotic diseases that are not commonly diagnosed in Israel...
May 30, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28719665/risk-factors-for-hospital-acquired-infections-in-teaching-hospitals-of-amhara-regional-state-ethiopia-a-matched-case-control-study
#3
Walelegn Worku Yallew, Abera Kumie, Feleke Moges Yehuala
BACKGROUND: Hospital-acquired infection affects hundreds of millions of people worldwide. It is a major global issue for patient safety. Understanding the potential risk factors is important to appreciate the local context. A matched case control study design, which is the first of its kind in the study region, was undertaken to identify risk factors in teaching hospitals of Amhara regional state, Ethiopia. METHOD: A matched case control study design matched with age and hospital type was used...
2017: PloS One
https://www.readbyqxmd.com/read/28719316/high-mortality-and-coinfection-in-a-prospective-cohort-of-human-immunodeficiency-virus-acquired-immune-deficiency-syndrome-patients-with-histoplasmosis-in-guatemala
#4
Blanca Samayoa, Monika Roy, Angela Ahlquist Cleveland, Narda Medina, Dalia Lau-Bonilla, Christina M Scheel, Beatriz L Gomez, Tom Chiller, Eduardo Arathoon
Histoplasmosis is one of the most common and deadly opportunistic infections among persons living with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome in Latin America, but due to limited diagnostic capacity in this region, few data on the burden and clinical characteristics of this disease exist. Between 2005 and 2009, we enrolled patients ≥ 18 years of age with suspected histoplasmosis at a hospital-based HIV clinic in Guatemala City. A case of suspected histoplasmosis was defined as a person presenting with at least three of five clinical or radiologic criteria...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28719311/infective-endocarditis-in-french-west-indies-a-13-year-observational-study
#5
Elisabeth Fernandes, Claude Olive, Jocelyn Inamo, François Roques, André Cabié, Patrick Hochedez
We conducted an observational study to describe the characteristics of infective endocarditis (IE) in French West Indies (FWI) and to identify variables associated with in-hospital case fatality. The records of the patients admitted for IE to the University Hospital of Martinique between 2000 and 2012 were collected using an electronic case report form. Only Duke-Li definite cases were considered for this analysis. Variables associated with in-hospital mortality were tested using univariate logistic regression analysis...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28714913/novel-fri1-like-viruses-infecting-acinetobacter-baumannii-vb_abap_as11-and-vb_abap_as12-characterization-comparative-genomic-analysis-and-host-recognition-strategy
#6
Anastasia V Popova, Daria G Lavysh, Evgeniy I Klimuk, Mikhail V Edelstein, Alexander G Bogun, Mikhail M Shneider, Artemiy E Goncharov, Sergey V Leonov, Konstantin V Severinov
Acinetobacter baumannii is a gram-negative, non-fermenting aerobic bacterium which is often associated with hospital-acquired infections and known for its ability to develop resistance to antibiotics, form biofilms, and survive for long periods in hospital environments. In this study, we present two novel viruses, vB_AbaP_AS11 and vB_AbaP_AS12, specifically infecting and lysing distinct multidrug-resistant clinical A. baumannii strains with K19 and K27 capsular polysaccharide structures, respectively. Both phages demonstrate rapid adsorption, short latent periods, and high burst sizes in one-step growth experiments...
July 17, 2017: Viruses
https://www.readbyqxmd.com/read/28714493/handwashing-practices-in-neonatal-intensive-care-unit-paediatric-intensive-care-unit-and-neonatal-nurseries-in-patan-hospital
#7
S Joshi, P Amatya, B Poudel, S A Yadav
BACKGROUND: Hand hygiene has been identified as the single most important factor in minimising hospital acquired infections. However, compliance of handwashing guidelines has remained low. The aim of this study was to study the handwashing practices in the Paediatric and Neonatal intensive care units and Neonatal nurseries in Patan Hospital, and secondly to re-evaluate the improvement on compliance of handwashing guidelines after intervention. METHODS: Pre-intervention study was conducted by covertly observing the handwashing practices by the healthcare workers...
January 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28713357/extensively-drug-resistant-klebsiella-pneumoniae-causing-nosocomial-bloodstream-infections-in-china-molecular-investigation-of-antibiotic-resistance-determinants-informing-therapy-and-clinical-outcomes
#8
Wenzi Bi, Haiyang Liu, Rhys A Dunstan, Bin Li, Von Vergel L Torres, Jianming Cao, Lijiang Chen, Jonathan J Wilksch, Richard A Strugnell, Trevor Lithgow, Tieli Zhou
The rise in diversity of antimicrobial resistance phenotypes seen in Klebsiella pneumoniae is becoming a serious antibiotic management problem. We sought to investigate the molecular characteristics and clinical implications of extensively drug-resistant (XDR) K. pneumoniae isolated from different nosocomial bloodstream infections (BSIs) patients from July 2013 to November 2015. Even in combination treatment, meropenem did not protect against mortality of BSIs patients (P = 0.015). In contrast, tigecycline in combination with other antimicrobial agents significantly protected against mortality (P = 0...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28712191/assessing-the-role-of-education-in-adult-women-s-knowledge-and-awareness-of-human-papillomavirus-and-human-papillomavirus-vaccine
#9
Humera Ismail, Sarah Rafiq, Shafia Shakoor, Muhammad Tariq Karim, Rabia Raheel
BACKGROUND: Awareness and knowledge of Human Papillomavirus (HPV) and HPV vaccine among women are not satisfactory in developing countries. The aim of this study was to assess the role of education in adult women about knowledge and awareness of human papillomavirus (HPV) and HPV vaccine. METHODS: This cross-sectional study was carried out in women aged 19- 50 years attending the out-patient waiting area of a tertiary care hospital in Karachi from August 2014 to August 2015...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28709485/biofilm-colonization-of-mycobacterium-abscessus-new-threat-in-hospital-acquired-surgical-site-infection
#10
Roumi Ghosh, Soumen Das, Harish Kela, Asmita De, Jayeeta Haldar, Prasanta Kumar Maiti
INTRODUCTION: Rapidly growing non-tuberculous mycobacteria (NTM) are hazardous cause of post-operative soft tissue infection leading to nosocomial outbreaks following various surgical procedures, especially laparoscopic surgeries using heat sensitive, non-autoclavable surgical instruments. METHODOLOGY: Surgery department of our hospital noticed increase in rate of post-laparoscopic abdominal port site infection (PSI) and informed the Microbiology Department. A prospective investigational study of defined cases with the aim of source tracing and formulation of infection control measures was initiated...
July 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28704006/-urinary-catheter-comply-with-guidelines-to-avoid-infections
#11
Elodie Miranda, Céline Boillat, Omar Kherad
Catheter-associated urinary tract infection (CAUTI) is the most frequent hospital acquired infection, associated with significant morbidity, mortality and health care costs. Up to 50 % of urinary catheter use in hospital are for incontinence or convenience without proper indication. In addition, urinary catheters are not removed when no longer necessary, due to a lack of vigilance of the health care team. The duration of catheterization is the most important risk factor for the development of CAUTI. Simple measures to prevent CAUTI include appropriate use, maintaining awareness of catheters in place and use of different alternatives...
January 25, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28702160/bk-virus-associated-hemorrhagic-cystitis-in-patients-with-allogeneic-hematopoietic-cell-transplantation-report-of-three-cases
#12
Duygu Mert, Hikmetullah Batgi, Alparslan Merdin, Sabahat Çeken, Mehmet Sinan Dal, Emre Tekgündüz, Fevzi Altuntaş, Mustafa Ertek
BK viras is a human polyoma viras. It is acquired in early childhood and remains life-long latent in the genitourinary system. BK virus replication is more common in receiving immunosuppressive therapy receiving patients and transplant patients. BK virus could cause hemorrhagic cystitis in patients with allogeneic stem cell transplantation. Hemorrhagic cystitis is a serious complication of hematopoietic stem cell transplantation. Hemorrhagic cystitis could cause morbidity and long stay in the hospital. Diagnosis is more frequently determined by the presence of BK virus DNA detected with quantitative or real-time PCR testing in serum or plasma and less often in urine...
June 1, 2017: Hematology Reports
https://www.readbyqxmd.com/read/28701266/community-acquired-bloodstream-infections-caused-by-acinetobacter-baumannii-a%C3%A2-matched-case-control-study
#13
Chung-Ting Chen, Yung-Chih Wang, Shu-Chen Kuo, Fang-Huy Shih, Te-Li Chen, Chorng-Kuang How, Ya-Sung Yang, Yi-Tzu Lee
BACKGROUND: Acinetobacter baumannii is an important nosocomial pathogen worldwide. Its role in community-acquired infection remains controversial and has rarely been reported. METHODS: Patients with monobacterial bloodstream infections caused by genomic species identified A. baumannii, admitted to Taipei Veterans General Hospital between 1999 and 2010, were selected as cases. Controls were defined as patients acquiring infection in a healthcare setting and were matched for age and sex...
June 29, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28701217/association-of-baseline-steroid-use-with-long-term-rates-of-infection-and-sepsis-in-the-regards-cohort
#14
Ninad S Chaudhary, John P Donnelly, Justin X Moore, John W Baddley, Monika M Safford, Henry E Wang
BACKGROUND: Prior studies associate steroid use with infection risk but were limited to select populations and short follow-up periods. The association of steroid use with long-term risk of community-acquired infections is unknown. We sought to determine the association of steroid risk with long-term risks of community- acquired infections and sepsis. METHODS: We used data on 30,239 adults aged ≥ 45 years old from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort...
July 13, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28701159/bacterial-bloodstream-infections-in-a-tertiary-infectious-diseases-hospital-in-northern-vietnam-aetiology-drug-resistance-and-treatment-outcome
#15
Vu Quoc Dat, Hieu Ngoc Vu, Hung Nguyen The, Hoa Thi Nguyen, Long Bao Hoang, Dung Vu Tien Viet, Chi Linh Bui, Kinh Van Nguyen, Trung Vu Nguyen, Dao Tuyet Trinh, Alessandro Torre, H Rogier van Doorn, Behzad Nadjm, Heiman F L Wertheim
BACKGROUND: Bloodstream infections (BSIs) are associated with high morbidity and mortality worldwide. However their aetiology, antimicrobial susceptibilities and associated outcomes differ between developed and developing countries. Systematic data from Vietnam are scarce. Here we present aetiologic data on BSI in adults admitted to a large tertiary referral hospital for infectious diseases in Hanoi, Vietnam. METHODS: A retrospective study was conducted at the National Hospital for Tropical Diseases between January 2011 and December 2013...
July 12, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28699964/antifungal-susceptibility-profile-of-diferent-yeasts-isolates-from-wild-animals-cow-s-milk-with-subclinical-mastitis-and-hospital-environment
#16
J F Mendes, C L Gonçalves, G F Ferreira, I A Esteves, C H Freitas, J P V Villarreal, J R B Mello, M C A Meireles, P S Nascente
Yeast infections have acquired great importance due to increasing frequency in immunocompromised patients or patients undergoing invasive diagnostic and therapeutic techniques, and also because of its high morbidity and mortality. At the same time, it has been seen an increase in the emergence of new pathogenic species difficult to diagnose and treat. The aim of this study was to determine the in vitro susceptibility of 89 yeasts from different sources against the antifungals amphotericin B, voriconazole, fluconazole and flucytosine, using the VITEK® 2 Compact system...
July 10, 2017: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/28699240/the-prevalence-of-peripheral-intravenous-cannulae-and-pattern-of-use-a-point-prevalence-in-a-private-hospital-setting
#17
Kelvin Wong, Alannah Cooper, Janie Brown, Leanne Boyd, Michele Levinson
AIMS AND OBJECTIVES: to determine the prevalence and pattern of use of peripheral intravenous cannula (PIVC) in hospital wards. BACKGROUND: PIVC are commonly used in acute health care to directly access the bloodstream for the administration of medications, intravenous fluids (IVF) and blood products. PIVC are associated with multiple adverse events including hospital acquired bloodstream infection, thrombophlebitis, and pain/discomfort. Administration of IVF is associated with impaired mobility and nocturia which may increase falls risk in the elderly...
July 12, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28697286/annual-burden-of-occupationally-acquired-influenza-infections-in-hospitals-and-emergency-departments-in-the-united-states
#18
Rachael M Jones, Yulin Xia
Infections among health-care personnel (HCP) occur as a result of providing care to patients with infectious diseases, but surveillance is limited to a few diseases. The objective of this study is to determine the annual number of influenza infections acquired by HCP as a result of occupational exposures to influenza patients in hospitals and emergency departments (EDs) in the United States. A risk analysis approach was taken. A compartmental model was used to estimate the influenza dose received in a single exposure, and a dose-response function applied to calculate the probability of infection...
July 11, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28697267/back-to-the-basics-community-acquired-pneumonia-in-children
#19
Kathleen Boyd
Community-acquired pneumonia (CAP) is a common childhood infection and often a reason for inpatient admission, especially when a child is hypoxic or in respiratory distress. Despite advances in technology and diagnostics, it remains difficult to accurately differentiate bacterial CAP from a viral process. Most of the laboratory tests routinely done in inpatient medicine, such as complete blood counts and acute phase reactants, do little to differentiate a viral pneumonia from a bacterial pneumonia. Clinicians must rely heavily on the clinical presentation and decide whether to treat empirically with antibiotics...
July 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/28695347/telavancin-in-the-treatment-of-concurrent-staphylococcus-aureus-bacteremia-a-retrospective-analysis-of-atlas-and-attain-studies
#20
Samuel E Wilson, Donald R Graham, Whedy Wang, Jon B Bruss, Bibiana Castaneda-Ruiz
INTRODUCTION: Concurrent Staphylococcus aureus bacteremia (SAB) worsens outcomes and increases mortality in patients with complicated skin and skin structure infections (cSSSI), hospital-acquired bacterial pneumonia, and ventilator-associated bacterial pneumonia (HABP/VABP). These challenges highlight the need for alternative treatments. Telavancin (TLV), a bactericidal lipoglycopeptide with high in vitro potency, effectively treats patients with cSSSI and HABP/VABP caused by Gram-positive pathogens, particularly S...
July 10, 2017: Infectious Diseases and Therapy
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