keyword
https://read.qxmd.com/read/38651540/interfacial-energy-as-an-approach-to-designing-amphipathic-surfaces-during-photopolymerization-curing
#1
JOURNAL ARTICLE
Sabrina J Curley, Caroline R Szczepanski
Photopolymerization induced phase separation (PIPS) is a platform capable of creating heterogeneous materials from initially miscible resin solutions, where both the reaction's governing thermodynamics and kinetics significantly influence the resulting phase composition and morphology. Here, PIPS is used to develop materials in a single photopolymerization step that are hydrophobic on one face and hydrophilic on the other. These two faces possess a water contact angle difference of 50°, bridged by a bulk-scale chemical gradient...
April 23, 2024: Soft Matter
https://read.qxmd.com/read/38651164/asymmetrical-disassortative-pollination-mediated-by-long-short-tongued-pollinators-in-a-distylous-limonium-myrianthum-plumbaginaceae-with-a-short-corolla-tubular-small-flower
#2
JOURNAL ARTICLE
Fangfang Jiao, Xiaowei Wang, Aiqin Zhang
In heterostylous plants, short-tongued pollinators are often ineffective/inefficient owing to the limitations imposed by a long corolla tube. However, it is unclear how disassortative pollen transfer is achieved in small flowers. We investigated the pollination pattern and floral morph variation by analyzing heterostylous syndrome, pollinator groups, and pollen deposition after a single visitation in two Limonium myrianthum populations with short-corolla-tubular small flowers. The predominant pollinators in the Hutubi population were pollen-seeking short-tongued syrphids, which can only transfer pollen between high-level sexual organs...
April 2024: Ecology and Evolution
https://read.qxmd.com/read/38651029/addiction-drug-use-and-usage-of-condoms-among-homosexual-males-a-cross-sectional-study
#3
JOURNAL ARTICLE
Yashowardhan V Totala, Abhiram M Kasbe
BACKGROUND: Despite the legal acceptance of homosexuality in India, it remains a social taboo, resulting in various challenges being faced by homosexual males. These challenges mainly include issues such as addiction/drug use and inconsistent and/ or incorrect condom usage which increase the risk of acquiring sexually transmitted infections (STIs) and HIV among them. This study was thus conducted with the objective of studying the patterns of addiction/drug use and condom usage among homosexual males...
February 2024: Addiction & Health
https://read.qxmd.com/read/38650964/striped-expression-of-leucine-rich-repeat-proteins-coordinates-cell-intercalation-and-compartment-boundary-formation-in-the-early-drosophila-embryo
#4
JOURNAL ARTICLE
Chloe A Kuebler, Adam C Paré
Planar polarity is a commonly observed phenomenon in which proteins display a consistent asymmetry in their subcellular localization or activity across the plane of a tissue. During animal development, planar polarity is a fundamental mechanism for coordinating the behaviors of groups of cells to achieve anisotropic tissue remodeling, growth, and organization. Therefore, a primary focus of developmental biology research has been to understand the molecular mechanisms underlying planar polarity in a variety of systems to identify conserved principles of tissue organization...
August 2023: Symmetry
https://read.qxmd.com/read/38649033/computer-vision-analysis-of-mother-infant-interaction-identified-efficient-pup-retrieval-in-v1b-receptor-knockout-mice
#5
JOURNAL ARTICLE
Chortip Sajjaviriya, Fujianti, Morio Azuma, Hiroyoshi Tsuchiya, Taka-Aki Koshimizu
Close contact between lactating rodent mothers and their infants is essential for effective nursing. Whether the mother's effort to retrieve the infants to their nest requires the vasopressin-signaling via V1b receptor has not been fully defined. To address this question, V1b receptor knockout (V1bKO) and control mice were analyzed in pup retrieval test. Because an exploring mother in a new test cage randomly accessed to multiple infants in changing backgrounds over time, a computer vision-based deep learning analysis was applied to continuously calculate the distances between the mother and the infants as a parameter of their relationship...
April 20, 2024: Peptides
https://read.qxmd.com/read/38647222/switchable-origami-adhesives
#6
JOURNAL ARTICLE
Wathsala M A Jayawardana, Theresa Elder, Timothy Twohig, Andrew B Croll
Creating a reusable adhesive that can hold objects on a wall and can yet be easily removed al for researchers in the adhesives community for many years. Geckos and other climbing organisms demonstrate just this ability: to hold large loads (on-state) due to specialized digits and microstructures, yet they are also able to quickly peel their feet from a surface while climbing (off-state). Inspired by the simplicity of the gecko's geometric switching mechanism, we have investigated the use of origami design methods to create geometries that can transition from a stiff configuration to a more flexible and easily peeled configuration...
April 22, 2024: Soft Matter
https://read.qxmd.com/read/38647066/extensive-long-range-polycomb-interactions-and-weak-compartmentalization-are-hallmarks-of-human-neuronal-3d-genome
#7
JOURNAL ARTICLE
Ilya A Pletenev, Maria Bazarevich, Diana R Zagirova, Anna D Kononkova, Alexander V Cherkasov, Olga I Efimova, Eugenia A Tiukacheva, Kirill V Morozov, Kirill A Ulianov, Dmitriy Komkov, Anna V Tvorogova, Vera E Golimbet, Nikolay V Kondratyev, Sergey V Razin, Philipp Khaitovich, Sergey V Ulianov, Ekaterina E Khrameeva
Chromatin architecture regulates gene expression and shapes cellular identity, particularly in neuronal cells. Specifically, polycomb group (PcG) proteins enable establishment and maintenance of neuronal cell type by reorganizing chromatin into repressive domains that limit the expression of fate-determining genes and sustain distinct gene expression patterns in neurons. Here, we map the 3D genome architecture in neuronal and non-neuronal cells isolated from the Wernicke's area of four human brains and comprehensively analyze neuron-specific aspects of chromatin organization...
April 22, 2024: Nucleic Acids Research
https://read.qxmd.com/read/38645721/hybrid-triboelectric-piezoelectric-nanogenerator-for-long-term-load-monitoring-in-total-knee-replacements
#8
JOURNAL ARTICLE
Mahmood Chahari, Emre Salman, Milutin Stanacevic, Ryan Willing, Shahrzad Towfighian
A self-powered and durable pressure sensor for large-scale pressure detection on the knee implant would be highly advantageous for designing long-lasting and reliable knee implants as well as obtaining information about knee function after the operation. The purpose of this study is to develop a robust energy harvester that can convert wide ranges of pressure to electricity to power a load sensor inside the knee implant. To efficiently convert loads to electricity, we design a cuboid-array-structured tribo-pizoelectric nanogenerator (TPENG) in vertical contact mode inside a knee implant package...
May 1, 2024: Smart Materials & Structures
https://read.qxmd.com/read/38645256/protocol-for-combined-n-of-1-trials-to-assess-cerebellar-neurostimulation-for-movement-disorders-in-children-and-young-adults-with-dyskinetic-cerebral-palsy
#9
Marta San Luciano, Carina R Oehrn, Sarah S Wang, John S Tolmie, Allisun Wiltshire, Rebecca E Graff, Jennifer Zhu, Philip A Starr
Background: Movement and tone disorders in children and young adults with cerebral palsy are a great source of disability. Deep brain stimulation (DBS) of basal ganglia targets has a major role in the treatment of isolated dystonias, but its efficacy in dyskinetic cerebral palsy (DCP) is lower, due to structural basal ganglia and thalamic damage and lack of improvement of comorbid choreoathetosis and spasticity. The cerebellum is an attractive target for DBS in DCP since it is frequently spared from hypoxic ischemic damage, it has a significant role in dystonia network models, and small studies have shown promise of dentate stimulation in improving CP-related movement and tone disorders...
April 1, 2024: Research Square
https://read.qxmd.com/read/38645010/adjacent-neuronal-fascicle-guides-motoneuron-24-dendritic-branching-and-axonal-routing-decisions-through-dscam1-signaling
#10
Kathy Clara Bui, Daichi Kamiyama
UNLABELLED: The formation and precise positioning of axons and dendrites are crucial for the development of neural circuits. Although juxtracrine signaling via cell-cell contact is known to influence these processes, the specific structures and mechanisms regulating neuronal process positioning within the central nervous system (CNS) remain to be fully identified. Our study investigates motoneuron 24 (MN24) in the Drosophila embryonic CNS, which is characterized by a complex yet stereotyped axon projection pattern, known as 'axonal routing...
April 12, 2024: bioRxiv
https://read.qxmd.com/read/38644460/electrospinning-of-poly-ethylene-oxide-glass-hybrid-nanofibres-for-anticounterfeiting-encoding
#11
JOURNAL ARTICLE
Mohamed H El-Newehy, Ali Aldalbahi, Badr M Thamer, Meera Moydeen Abdulhameed
The use of photochromism to increase the credibility of consumer goods has shown great promise. To provide mechanically dependable anticounterfeiting nanofibres, it has also been critical to improve the engineering processes of authentication patterns. Mechanically robust and photoluminescent electrospun poly(ethylene oxide)/glass (PGLS) nanofibres (150-350 nm) immobilized with nanoparticles of lanthanide-doped aluminate (NLA; 8-15 nm) were developed using electrospinning technology for anticounterfeiting purposes...
April 2024: Luminescence: the Journal of Biological and Chemical Luminescence
https://read.qxmd.com/read/38644332/rapid-in-plane-pattern-growth-for-large-area-inverse-replication-through-electrohydrodynamic-instability-of-polymer-films
#12
JOURNAL ARTICLE
Hyunje Park, Jaeseok Hwang, Heejoon Chae, Dae Joon Kang
Nanopatterning driven by electrohydrodynamic (EHD) instability can aid in the resolution of the drawbacks inherent in conventional imprinting or other molding methods. This is because EHD force negates the requirement of physical contact and is easily tuned. However, its potential has not examined owing to the limited size of the pattern replica (several to tens of micrometers). Thus, this study proposes a new route for large-area patterning through high-speed evolution of EHD-driven pattern growth along the in-plane axis...
April 21, 2024: Small
https://read.qxmd.com/read/38642570/global-incidence-prevalence-years-lived-with-disability-ylds-disability-adjusted-life-years-dalys-and-healthy-life-expectancy-hale-for-371-diseases-and-injuries-in-204-countries-and-territories-and-811-subnational-locations-1990-2021-a-systematic-analysis-for
#13
JOURNAL ARTICLE
(no author information available yet)
BACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases...
April 15, 2024: Lancet
https://read.qxmd.com/read/38640816/dynamics-of-microbiota-and-antimicrobial-resistance-in-on-farm-dairy-processing-plants-using-metagenomic-and-culture-dependent-approaches
#14
JOURNAL ARTICLE
Saehah Yi, Hyokeun Song, Woo-Hyun Kim, Soomin Lee, Jae-Ho Guk, JungHa Woo, Seongbeom Cho
On-farm dairy processing plants, which are situated close to farms and larger dairy processing facilities, face unique challenges in maintaining environmental hygiene. This can impact various stages of dairy processing. These plants operate on smaller scales and use Low-Temperature-Long-Time (LTLT) pasteurization, making them more susceptible to microbial contamination through direct and indirect contact. Antimicrobial-resistant bacteria found on dairy farms pose risks to human health by potentially transferring resistance via dairy products...
April 14, 2024: International Journal of Food Microbiology
https://read.qxmd.com/read/38640476/ai-led-mental-health-support-wysa-for-health-care-workers-during-covid-19-service-evaluation
#15
JOURNAL ARTICLE
Christel Lynne Chang, Chaitali Sinha, Madhavi Roy, John Chee Meng Wong
BACKGROUND: The impact that the COVID-19 pandemic has had on health care workers' mental health, in particular, cannot be ignored. Not only did the pandemic exacerbate mental health challenges through elevated stress, anxiety, risk of infection, and social isolation, but regulations to minimize infection additionally hindered the conduct of traditional in-person mental health care. OBJECTIVE: This study explores the feasibility of using Wysa, an artificial intelligence-led mental health app, among health care workers...
April 19, 2024: JMIR Formative Research
https://read.qxmd.com/read/38636334/gait-variability-fractal-dynamics-and-statistical-regularity-of-treadmill-and-overground-walking-recorded-with-a-smartphone
#16
JOURNAL ARTICLE
Vincenzo E Di Bacco, William H Gage
BACKGROUND: The nonlinear variability present during steady-state gait may provide a signature of health and showcase one's walking adaptability. Although treadmills can capture vast amounts of walking data required for estimating variability within a small space, gait patterns may be misrepresented compared to an overground setting. Smartphones may provide a low-cost and user-friendly estimate of gait patterns among a variety of walking settings. However, no study has investigated differences in gait patterns derived from a smartphone between treadmill walking (TW) and overground walking (OW)...
April 17, 2024: Gait & Posture
https://read.qxmd.com/read/38634630/lateral-ankle-joint-injuries-in-indoor-and-court-sports-a-systematic-video-analysis-of-445-nonconsecutive-case-series
#17
JOURNAL ARTICLE
Timo Bagehorn, Mark de Zee, Daniel T P Fong, Kristian Thorborg, Uwe G Kersting, Filip Gertz Lysdal
BACKGROUND: Lateral ankle sprains are one of the most common injuries in indoor and court sports. Self-reports and case studies have indicated that these injuries occur via both contact and noncontact injury mechanisms typically because of excessive inversion in combination with plantarflexion and adduction of the foot. Video-based documentation of the injury mechanism exists, but the number of cases reported in the literature is limited. PURPOSE: To retrieve and systematically analyze a large number of video-recorded lateral ankle injuries from indoor and court sports, as well as describe the injury mechanism, injury motion, and injury pattern across different sports...
April 18, 2024: American Journal of Sports Medicine
https://read.qxmd.com/read/38630324/is-3t-mr-nerve-bone-fusion-imaging-a-viable-alternative-to-mri-cbct-to-identify-the-relationship-between-the-inferior-alveolar-nerve-and-mandibular-third-molar
#18
JOURNAL ARTICLE
Hao Huang, Yalan Yan, Dongmei Jiang, Xiance Zhao, Dairong Cao, Dejun She
OBJECTIVES: To investigate the feasibility of MRI nerve-bone fusion imaging in assessing the relationship between inferior alveolar nerve (IAN) / mandibular canal (MC) and mandibular third molar (MTM) compared with MRI-CBCT fusion. MATERIALS AND METHODS: The MRI nerve-bone fusion and MRI-CBCT fusion imaging were performed in 20 subjects with 37 MTMs. The Hausdorff distance (HD) value and dice similarity coefficient (DSC) was calculated. The relationship between IAN/MC and MTM roots, inflammatory, and fusion patterns were compared between these two fused images...
April 17, 2024: Clinical Oral Investigations
https://read.qxmd.com/read/38627385/programmable-photoacoustic-patterning-of-microparticles-in-air
#19
JOURNAL ARTICLE
Ruoqin Zhang, Xichuan Zhao, Jinzhi Li, Di Zhou, Honglian Guo, Zhi-Yuan Li, Feng Li
Optical and acoustic tweezers, despite operating on different physical principles, offer non-contact manipulation of microscopic and mesoscopic objects, making them essential in fields like cell biology, medicine, and nanotechnology. The advantages and limitations of optical and acoustic manipulation complement each other, particularly in terms of trapping size, force intensity, and flexibility. We use photoacoustic effects to generate localized Lamb wave fields capable of mapping arbitrary laser pattern shapes...
April 16, 2024: Nature Communications
https://read.qxmd.com/read/38627256/two-photon-lithography-for-customized-microstructured-surfaces-and-their-influence-on-wettability-and-bacterial-load
#20
JOURNAL ARTICLE
Sophie Nilsson Zagiczek, Matthias Weiss-Tessbach, Manuel Kussmann, Doris Moser, Martin Stoiber, Francesco Moscato, Heinrich Schima, Christian Grasl
BACKGROUND: Device-related bacterial infections account for a large proportion of hospital-acquired infections. The ability of bacteria to form a biofilm as a protective shield usually makes treatment impossible without removal of the implant. Topographic surfaces have attracted considerable attention in studies seeking antibacterial properties without the need for additional antimicrobial substances. As there are still no valid rules for the design of antibacterial microstructured surfaces, a fast, reproducible production technique with good resolution is required to produce test surfaces and to examine their effectiveness with regard to their antibacterial properties...
April 17, 2024: 3D Printing in Medicine
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