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https://www.readbyqxmd.com/read/28107400/when-contact-is-not-enough-affecting-first-year-medical-students-image-towards-older-persons
#1
Sasmita Kusumastuti, Esther van Fenema, Eugenie C F Polman-van Stratum, Wilco Achterberg, Jolanda Lindenberg, Rudi G J Westendorp
CONTEXT: Many medical schools have initiated care internships to familiarize their students with older persons and to instil a professional attitude. OBJECTIVE: To examine the impact of care internships on the image that first-year medical students have of older persons and to explore the underlying concepts that may play a role in shaping this image. DESIGN: Survey before and after a two-week compulsory care internship using the Aging Semantic Differential (ASD; 32 adjectives) and the Attitudes toward Old People (AOP; 34 positions) questionnaires...
2017: PloS One
https://www.readbyqxmd.com/read/28105494/suicide-with-two-makes-of-captive-bolt-guns-livestock-stunners-fired-simultaneously-to-the-forehead
#2
Rebecca Pircher, Dorothee Geisenberger, Markus Große Perdekamp, Merja Neukamm, Stefan Pollak, Ulrike Schmidt, Annette Thierauf-Emberger
In humans, most fatalities from slaughterer's guns are suicides committed by persons familiar with stunning devices. The great majority of cases accounts for shots to the head, especially the frontal region. Only a small number of two subsequent cranial shots from captive-bolt humane killers have been reported up to now. In the case presented by the authors, a suicide by simultaneous shots to the head fired from two different makes of captive-bolt guns (one of them having two separate outlets for the combustion gases in the muzzle plane, the other type having no additional openings) is described for the first time...
January 20, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28102576/printable-functional-chips-based-on-nanoparticle-assembly
#3
REVIEW
Yu Huang, Wenbo Li, Meng Qin, Haihua Zhou, Xingye Zhang, Fengyu Li, Yanlin Song
With facile manufacturability and modifiability, impressive nanoparticles (NPs) assembly applications were performed for functional patterned devices, which have attracted booming research attention due to their increasing applications in high-performance optical/electrical devices for sensing, electronics, displays, and catalysis. By virtue of easy and direct fabrication to desired patterns, high throughput, and low cost, NPs assembly printing is one of the most promising candidates for the manufacturing of functional micro-chips...
January 2017: Small
https://www.readbyqxmd.com/read/28102074/growth-of-a-large-area-free-standing-highly-conductive-and-fully-foldable-silver-film-with-inverted-pyramids-for-wearable-electronics-applications
#4
Xiao Yu, Zihua Li, Yong Liu, Wen-Xia Zhao, Ruimei Xu, Donghai Wang, Hui Shen
A promising new concept is the application of flexible and foldable conductive film or paper for wearable electronics, in which silver nanowires, carbon nanotubes and graphene are primarily used as conductive materials. However, their insufficient nanostructure contacts lead to poor electrical conductivity and mechanical fracture. Here, we demonstrate a simple and innovative strategy for fabricating a free-standing silver film with inverted pyramids by replicating pyramids on a textured silicon wafer under a hydrothermal reaction...
January 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28101944/biomechanical-implications-of-walking-with-indigenous-footwear
#5
Catherine Willems, Gaetane Stassijns, Wim Cornelis, Kristiaan D'Août
OBJECTIVES: This study investigates biomechanical implications of walking with indigenous "Kolhapuri" footwear compared to barefoot walking among a population of South Indians. MATERIALS AND METHODS: Ten healthy adults from South India walked barefoot and indigenously shod at voluntary speed on an artificial substrate. The experiment was repeated outside, on a natural substrate. Data were collected from (1) a heel-mounted 3D-accelerometer recording peak impact at heel contact, (2) an ankle-mounted 3D-goniometer (plantar/dorsiflexion and inversion/eversion), and (3) sEMG electrodes at the m...
January 19, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28100938/public-perceptions-of-plastic-surgery-practice-in-brazil
#6
Rafael Denadai, Karin Milleni Araujo, Hugo Samartine, Rodrigo Denadai, Cassio Eduardo Raposo-Amaral
The perception of medical specialists by the public has a significant effect on health-care decisions, research funding allocation, and implantation of educational measures. The purpose of this survey was to assess the public's perception of the field of plastic surgery practice. General public members (n = 1290) completed a survey where they matched nine specialties with 28 plastic surgery-related scenarios. Response patterns were distributed as "plastic surgeon alone," "plastic surgeon combined with other specialists," or "no plastic surgeon...
December 2016: Indian Journal of Surgery
https://www.readbyqxmd.com/read/28100443/surveillance-of-antimicrobial-use-in-dutch-long-term-care-facilities
#7
Monique Roukens, Linda Verhoef, Ellen Stobberingh, Stephanie Natsch
OBJECTIVES: Residents living in a long-term care facility (LTCF) are more susceptible to infections. Treatment with antimicrobials is sometimes necessary; however, antibiotic use is considered one of the most important drivers of the development of antibiotic resistance. Surveillance data on antibiotic use in these LTCFs are necessary to get more insight into these patterns. The objective of this study was to describe antibiotic use in LTCFs in the Netherlands. METHODS: One hundred and seventy-seven LTCFs in the Netherlands were contacted and asked to participate in a study concerning antibiotic resistance and antibiotic use...
January 18, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28100168/effects-of-pleistocene-sea-level-fluctuations-on-mangrove-population-dynamics-a-lesson-from-sonneratia-alba
#8
Yuchen Yang, Jianfang Li, Shuhuan Yang, Xinnian Li, Lu Fang, Cairong Zhong, Norman C Duke, Renchao Zhou, Suhua Shi
BACKGROUND: A large-scale systematical investigation of the influence of Pleistocene climate oscillation on mangrove population dynamics could enrich our knowledge about the evolutionary history during times of historical climate change, which in turn may provide important information for their conservation. RESULTS: In this study, phylogeography of a mangrove tree Sonneratia alba was studied by sequencing three chloroplast fragments and seven nuclear genes. A low level of genetic diversity at the population level was detected across its range, especially at the range margins, which was mainly attributed to the steep sea-level drop and associated climate fluctuations during the Pleistocene glacial periods...
January 18, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28099503/3d-functional-corneal-stromal-tissue-equivalent-based-on-corneal-stromal-stem-cells-and-multi-layered-silk-film-architecture
#9
Chiara E Ghezzi, Benedetto Marelli, Fiorenzo G Omenetto, James L Funderburgh, David L Kaplan
The worldwide need for human cornea equivalents continues to grow. Few clinical options are limited to allogenic and synthetic material replacements. We hypothesized that tissue engineered human cornea systems based on mechanically robust, patterned, porous, thin, optically clear silk protein films, in combination with human corneal stromal stem cells (hCSSCs), would generate 3D functional corneal stroma tissue equivalents, in comparison to previously developed 2D approaches. Silk film contact guidance was used to control the alignment and distribution of hCSSCs on RGD-treated single porous silk films, which were then stacked in an orthogonally, multi-layered architecture and cultured for 9 weeks...
2017: PloS One
https://www.readbyqxmd.com/read/28099479/social-contact-structures-and-time-use-patterns-in-the-manicaland-province-of-zimbabwe
#10
Alessia Melegaro, Emanuele Del Fava, Piero Poletti, Stefano Merler, Constance Nyamukapa, John Williams, Simon Gregson, Piero Manfredi
BACKGROUND: Patterns of person-to-person contacts relevant for infectious diseases transmission are still poorly quantified in Sub-Saharan Africa (SSA), where socio-demographic structures and behavioral attitudes are expected to be different from those of more developed countries. METHODS AND FINDINGS: We conducted a diary-based survey on daily contacts and time-use of individuals of different ages in one rural and one peri-urban site of Manicaland, Zimbabwe. A total of 2,490 diaries were collected and used to derive age-structured contact matrices, to analyze time spent by individuals in different settings, and to identify the key determinants of individuals' mixing patterns...
2017: PloS One
https://www.readbyqxmd.com/read/28096420/drivers-of-rift-valley-fever-epidemics-in-madagascar
#11
Renaud Lancelot, Marina Béral, Vincent Michel Rakotoharinome, Soa-Fy Andriamandimby, Jean-Michel Héraud, Caroline Coste, Andrea Apolloni, Cécile Squarzoni-Diaw, Stéphane de La Rocque, Pierre B H Formenty, Jérémy Bouyer, G R William Wint, Eric Cardinale
Rift Valley fever (RVF) is a vector-borne viral disease widespread in Africa. The primary cycle involves mosquitoes and wild and domestic ruminant hosts. Humans are usually contaminated after contact with infected ruminants. As many environmental, agricultural, epidemiological, and anthropogenic factors are implicated in RVF spread, the multidisciplinary One Health approach was needed to identify the drivers of RVF epidemics in Madagascar. We examined the environmental patterns associated with these epidemics, comparing human and ruminant serological data with environmental and cattle-trade data...
January 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28096084/timesvector-a-vectorized-clustering-approach-to-the-analysis-of-time-series-transcriptome-data-from-multiple-phenotypes
#12
Inuk Jung, Kyuri Jo, Hyejin Kang, Hongryul Ahn, Youngjae Yu, Sun Kim
MOTIVATION: Identifying biologically meaningful gene expression patterns from time series gene expression data is important to understand the underlying biological mechanisms. To identify significantly perturbed gene sets between different phenotypes, analysis of time series transcriptome data requires consideration of time and sample dimensions. Thus, the analysis of such time series data seeks to search gene sets that exhibit similar or different expression patterns between two or more sample conditions, constituting the three-dimensional data, i...
January 17, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28095646/a-frog-s-view-of-ephrinb-signaling
#13
REVIEW
Yoo-Seok Hwang, Ira O Daar
Cell-cell and cell-substrate adhesion are essential to the proper formation and maintenance of tissue patterns during development, and deregulation of these processes can lead to invasion and metastasis of cancer cells. Cell surface adhesion and signaling molecules are key players in both normal development and cancer progression. One set of cell surface proteins, the Eph receptor tyrosine kinases and their membrane-bound ligands, ephrins, are significant regulators of these processes. During embryonic development, the Eph/ephrin signaling system is involved in cell-cell contact events that result in cell sorting and boundary formation between receptor and ligand bearing cells...
January 17, 2017: Genesis: the Journal of Genetics and Development
https://www.readbyqxmd.com/read/28094970/octagon-to-square-wetting-area-transition-of-water-ethanol-droplets-on-micro-pyramid-substrate-by-increasing-ethanol-concentration
#14
Huicheng Feng, Karen Siew-Ling Chong, Kian Soo Ong, Fei Duan
The wettability and evaporation of water-ethanol binary droplets on the substrate with micro-pyramid cavities are studied by controlling initial ethanol concentrations. The droplets form octagonal initial wetting areas on the substrate. As the ethanol concentration increases, the side ratio of the initial wetting octagon increases from 1.5 at 0% of ethanol concentration to 3.5 at 30% of ethanol concentration. The increasing side ratio indicates that the wetting area transforms from an octagon to a square if we consider the octagon as a square with its four corners cut...
January 17, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28093905/inkjet-printing-of-soft-stretchable-optical-waveguides-through-the-photopolymerization-of-high-profile-linear-patterns
#15
Aleksandra Samusjew, Markus Kratzer, Andreas Moser, Christian Teichert, Krzysztof Konrad Krawczyk, Thomas Griesser
Optical waveguides have been fabricated via photopolymerization of stable, inkjet-printed patterns. In order to obtain high-profile lines, the properties of both the ink and the substrate were adjusted. We prove that suitable patterns, with contact angles close to 90˚, can be printed by using not fully cured, 'sticky' PDMS as a substrate. In addition, we propose a simple sliding-drop experiment to show the crucial difference in how the ink dewets the 'sticky' and the fully cured substrate, which is otherwise difficult to demonstrate...
January 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28093404/development-and-application-of-an-algorithm-to-compute-weighted-multiple-glycan-alignments
#16
Masae Hosoda, Yukie Akune, Kiyoko F Aoki-Kinoshita
MOTIVATION: A glycan consists of monosaccharides linked by glycosidic bonds, has branches and forms complex molecular structures. Databases have been developed to store large amounts of glycan-binding experiments, including glycan arrays with glycan binding proteins (GBPs). However, there are few bioinformatics techniques to analyze large amounts of data for glycans because there are few tools that can handle the complexity of glycan structures. Thus, we have developed the MCAW (Multiple Carbohydrate Alignment with Weights) tool that can align multiple glycan structures, to aid in the understanding of their function as binding recognition molecules...
January 16, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28089709/objective-assessment-of-dietary-patterns-by-use-of-metabolic-phenotyping-a-randomised-controlled-crossover-trial
#17
Isabel Garcia-Perez, Joram M Posma, Rachel Gibson, Edward S Chambers, Tue H Hansen, Henrik Vestergaard, Torben Hansen, Manfred Beckmann, Oluf Pedersen, Paul Elliott, Jeremiah Stamler, Jeremy K Nicholson, John Draper, John C Mathers, Elaine Holmes, Gary Frost
BACKGROUND: Accurate monitoring of changes in dietary patterns in response to food policy implementation is challenging. Metabolic profiling allows simultaneous measurement of hundreds of metabolites in urine, the concentrations of which can be affected by food intake. We hypothesised that metabolic profiles of urine samples developed under controlled feeding conditions reflect dietary intake and can be used to model and classify dietary patterns of free-living populations. METHODS: In this randomised, controlled, crossover trial, we recruited healthy volunteers (aged 21-65 years, BMI 20-35 kg/m(2)) from a database of a clinical research unit in the UK...
January 12, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/28088762/the-super-n-motifs-model-a-novel-alignment-free-approach-for-representing-and-comparing-rna-secondary-structures
#18
Jean-Pierre Séhi Glouzon, Jean-Pierre Perreault, Shengrui Wang
MOTIVATION: Comparing ribonucleic acid (RNA) secondary structures of arbitrary size uncovers structural patterns that can provide a better understanding of RNA functions. However, performing fast and accurate secondary structure comparisons is challenging when we take into account the RNA configuration (i.e. linear or circular), the presence of pseudoknot and G-quadruplex (G4) motifs and the increasing number of secondary structures generated by high-throughput probing techniques. To address this challenge, we propose the super-n-motifs model based on a latent analysis of enhanced motifs comprising not only basic motifs but also adjacency relations...
January 14, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28088279/archaeometric-analysis-of-roman-bronze-coins-from-the-magna-mater-temple-using-solid-state-voltammetry-and-electrochemical-impedance-spectroscopy
#19
Francesca Di Turo, Noemí Montoya, Joan Piquero-Cilla, Caterina De Vito, Fulvio Coletti, Gabriele Favero, Antonio Doménech-Carbó
Voltammetry of microparticles (VMP) and electrochemical impedance spectroscopy (EIS) techniques, complemented by SEM-EDX and Raman spectroscopy, were applied to a set of 15 Roman bronze coins and one Tessera from the temple of Magna Mater (Rome, Italy). The archaeological site, dated back between the second half and the end of the 4th century A.D., presented a complicated stratigraphic context. Characteristic voltammetric patterns for cuprite and tenorite for sub-microsamples of the corrosion layers of the coins deposited onto graphite electrodes in contact with 0...
February 22, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28087774/the-origin-of-mitochondrial-cristae-from-alphaproteobacteria
#20
Sergio A Muñoz-Gómez, Jeremy G Wideman, Andrew J Roger, Claudio H Slamovits
Mitochondria are the respiratory organelles of eukaryotes and their evolutionary history is deeply intertwined with that of eukaryotes. The compartmentalization of respiration in mitochondria occurs within cristae, whose evolutionary origin has remained unclear. Recent discoveries, however, have revived the old notion that mitochondrial cristae could have had a pre-endosymbiotic origin. Mitochondrial cristae are likely homologous to the intracytoplasmic membranes (ICMs) used by diverse alphaproteobacteria for harnessing energy...
January 12, 2017: Molecular Biology and Evolution
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