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https://www.readbyqxmd.com/read/28742604/disparities-in-athletic-trainer-staffing-in-secondary-school-sport-implications-for-concussion-identification
#1
Emily Kroshus, Frederick P Rivara, Kathryn B Whitlock, Stanley A Herring, Sara P D Chrisman
OBJECTIVE: First, to assess whether teams at schools with an athletic trainer (AT) on staff had a higher number of diagnosed concussions than teams without medical personnel present. Second, to assess whether the variability in employment of a certified AT by Washington state high schools is patterned by socioeconomic and demographic characteristics. DESIGN: Cross-sectional survey. SETTING: Washington state public high schools. PARTICIPANTS: Stratified random sample of football and soccer coaches (n = 270 teams, 144 schools)...
July 21, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28742277/the-immediate-and-short-term-effects-of-real-time-knee-adduction-moment-feedback-on-the-peak-and-cumulative-knee-load-during-walking
#2
Brennan Jackson, Keith E Gordon, Alison H Chang
The peak external knee adduction moment (pKAM), KAM impulse, and peak knee flexion moment (pKFM) during gait are important loading variables in medial tibiofemoral osteoarthritis. We evaluated the effects of gait modification, using real-time pKAM visual feedback, on pKAM, KAM impulse, and pKFM; and whether participants could maintain the KAM-reducing gait after feedback removal. Eleven healthy individuals performed a series of walking trials on a split-belt instrumented treadmill under 4 conditions of Baseline, Feedback, No Feedback Early, and No Feedback Late...
July 25, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28742097/mrtadfinder-a-network-modularity-based-approach-to-identify-topologically-associating-domains-in-multiple-resolutions
#3
Koon-Kiu Yan, Shaoke Lou, Mark Gerstein
Genome-wide proximity ligation based assays such as Hi-C have revealed that eukaryotic genomes are organized into structural units called topologically associating domains (TADs). From a visual examination of the chromosomal contact map, however, it is clear that the organization of the domains is not simple or obvious. Instead, TADs exhibit various length scales and, in many cases, a nested arrangement. Here, by exploiting the resemblance between TADs in a chromosomal contact map and densely connected modules in a network, we formulate TAD identification as a network optimization problem and propose an algorithm, MrTADFinder, to identify TADs from intra-chromosomal contact maps...
July 24, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28741843/niche-differences-may-explain-the-geographic-distribution-of-cytotypes-in-erysimum-mediohispanicum
#4
A Jesus Muñoz-Pajares, Francisco Perfectti, João Loureiro, Mohamed Abdelaziz, Paolo Biella, Mariana Castro, Sílvia Castro, Jose M Gómez
Polyploidization has played an important role in plant diversification, and variation in ploidy level may be found not only between species of the same genus, but also within a single species. Although establishing the adaptive significance of polyploidy to explain the geographic distribution of cytotypes is challenging, the occurrence of different cytotypes in different ecological niches may suggest an adaptive role of genome duplication. We have studied the adaptive significance of the geographic distribution of cytotypes across the entire distribution range of the endemic Erysimum mediohispanicum (Brassicaceae)...
July 25, 2017: Plant Biology
https://www.readbyqxmd.com/read/28741257/the-comorbidity-burden-of-patients-with-cluster-headache-a-population-based-study
#5
Shivang Joshi, Paul Rizzoli, Elizabeth Loder
BACKGROUND: Evidence is limited regarding the comorbidity burden of patients with cluster headache (CH). We aimed to characterize comorbid conditions in a cohort of CH patients diagnosed by headache experts, using electronic health record information from the Partners Research Patient Data Registry (RPDR). METHODS: We identified and reviewed the charts of unique patients diagnosed by headache specialists over an 11-year period, and a set of matched controls. Patients were categorized as having Definite, Unconfirmed or no CH...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28740772/relationship-between-keloid-formation-and-yap-taz-signaling
#6
Noriko Aramaki-Hattori, Keisuke Okabe, Mariko Hamada, Tamae Takato, Kazuo Kishi
YAP (yes-associated protein) and TAZ (transcriptional coactivator with PDZ-binding motif) are part of a classical pathway that controls contact inhibition in the Hippo pathway. YAP and TAZ were recently reported to act as nuclear relays of mechanical signals that communicate extracellular matrix rigidity and cell shape. However, the role of YAP/TAZ signaling in keloid formation is unclear. Here, we used immunohistochemistry to investigate YAP/TAZ expression in keloid and nonaffected lesions. YAP/TAZ expression in keloid fibroblasts had a greater tendency to localize to the nucleus relative to that seen in fibroblasts from unaffected tissues...
June 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28740514/normal-versus-pathological-cardiac-fibroblast-derived-extracellular-matrix-differentially-modulates-cardiosphere-derived-cell-paracrine-properties-and-commitment
#7
Francesca Pagano, Francesco Angelini, Clotilde Castaldo, Vittorio Picchio, Elisa Messina, Sebastiano Sciarretta, Ciro Maiello, Giuseppe Biondi-Zoccai, Giacomo Frati, Franca di Meglio, Daria Nurzynska, Isotta Chimenti
Human resident cardiac progenitor cells (CPCs) isolated as cardiosphere-derived cells (CDCs) are under clinical evaluation as a therapeutic product for cardiac regenerative medicine. Unfortunately, limited engraftment and differentiation potential of transplanted cells significantly hamper therapeutic success. Moreover, maladaptive remodelling of the extracellular matrix (ECM) during heart failure progression provides impaired biological and mechanical signals to cardiac cells, including CPCs. In this study, we aimed at investigating the differential effect on the phenotype of human CDCs of cardiac fibroblast-derived ECM substrates from healthy or diseased hearts, named, respectively, normal or pathological cardiogel (CG-N/P)...
2017: Stem Cells International
https://www.readbyqxmd.com/read/28739023/suture-bridge-transosseous-equivalent-repair-is-stronger-than-transosseous-tied-braided-tape
#8
Jérémie Ménard, Benjamin Léger-St-Jean, Frédéric Balg, Yvan Petit, Marc Beauchamp, Dominique M Rouleau
BACKGROUND: This study biomechanically compares two methods of supraspinatus repair: single row transosseous braided-tape (BT) and suture bridge transosseous equivalent (SBTE) with 2 medial anchors and 2 lateral anchors. The purpose is to test the hypothesis that BT provides superior or equal biomechanical strength compared to SBTE. METHODS: Nine pairs of frozen cadaveric shoulders were selected and both repair techniques were tested on each pair, using a biomechanical testing unit to measure cyclic loading and ultimate load to failure...
July 21, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28737930/self-collapse-lithography
#9
Chuanzhen Zhao, Xiaobin Xu, Qing Yang, Tianxing Man, Steven Jonas, Jeffrey J Schwartz, Anne M Andrews, Paul S Weiss
We report a facile, high-throughput soft lithography process that utilizes nanoscale channels formed naturally at the edges of microscale relief features on soft, elastomeric stamps. Upon contact with self-assembled monolayer (SAM) functionalized substrates, the roof of the stamp collapses, resulting in the selective removal of SAM molecules via a chemical lift-off process. With this technique, which we call self-collapse lithography (SCL), sub-30-nm patterns were achieved readily using masters with microscale features prepared by conventional photolithography...
July 24, 2017: Nano Letters
https://www.readbyqxmd.com/read/28737833/the-natural-history-of-oviposition-on-a-ginkgophyte-fruit-from-the-middle-jurassic-of-northeastern-china
#10
Qing-Min Meng, Conrad C Labandeira, Qiao-Ling Ding, Dong Ren
A distinctive pattern of oviposition lesions occurs on a ginkgoalean seed, Yimaia capituliformis, which likely was inflicted by a kalligrammatid lacewing with a long, sword-like, plant piercing ovipositor. This newly recorded oviposition type, DT272, occurs in the 165 million-year-old Jiulongshan Formation, of Middle Jurassic age, in Northeastern China. DT272 consists from three to seven, approximately equally spaced lesions with surrounding callus tissue whose fabricator targeted fleshy outer and inner tissues of a ginkgophyte fruit...
July 24, 2017: Insect Science
https://www.readbyqxmd.com/read/28735104/effect-of-limb-dominance-and-sex-on-neuromuscular-activation-patterns-in-athletes-under-12-performing-unanticipated-side-cuts
#11
Michael J Del Bel, Alana K Fairfax, Michelle L Jones, Kendal Steele, Scott C Landry
Non-contact ACL injuries are one of the most common injuries to the knee joint among adolescent/collegiate athletes, with sex and limb dominance being identified as risk factors. In children under 12years of age (U12), these injuries occur less often and there is no sex-bias present. This study set out to explore if sex and/or limb dominance differences exist in neuromuscular activations in U12 athletes. Thirty-four U12 males and females had six bilateral muscles analyzed during unanticipated side-cuts. Principal component analysis was performed, capturing differences in overall magnitudes and timing of peak magnitudes...
July 14, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28732995/ultrasonic-assisted-fabrication-and-characterization-of-pvc-sio2-nanocomposites-having-bovine-serum-albumin-as-a-bio-coupling-agent
#12
Shadpour Mallakpour, Hossein Yazdan Nazari
In this work, SiO2 nanoparticles (NPs) were modified with bovine serum albumin (BSA) under ultrasound irradiations as a green and fast route to achieve their good dispersion. Subsequently, different weight percentages of the modified NPs (3, 6, and 9wt%) were incorporated in poly(vinyl chloride) (PVC) as the matrix. Thermogravimetric analysis of the SiO2-BSA NPs indicated that 12wt% of the modifier was loaded on the surface of SiO2 NPs. Encapsulation of the SiO2-BSA resulted in a meaningful improvement in the optical, mechanical and thermal characteristics of the prepared PVC nanocomposites (NCs)...
November 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28732986/continuous-flow-ultrasound-assisted-oxidative-desulfurization-uaod-process-an-efficient-diesel-treatment-by-injection-of-the-aqueous-phase
#13
Masoud Rahimi, Shahrokh Shahhosseini, Salman Movahedirad
A new continuous-flow ultrasound assisted oxidative desulfurization (UAOD) process was developed in order to decrease energy and aqueous phase consumption. In this process the aqueous phase is injected below the horn tip leading to enhanced mixing of the phases. Diesel fuel as the oil phase with sulfur content of 1550ppmw and an appropriate mixture of hydrogen peroxide and formic acid as the aqueous phase were used. At the first step, the optimized condition for the sulfur removal has been obtained in the batch mode operation...
November 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28731978/differences-in-spatiotemporal-parameters-between-trained-runners-and-untrained-participants
#14
Josué Gómez-Molina, Ana Ogueta-Alday, Christopher Stickley, Jesús Cámara, Jon Cabrejas-Ugartondo, Juan García-López
Gómez-Molina, J, Ogueta-Alday, A, Stickley, C, Tobalina, JC, Cabrejas-Ugartondo, J, and García-López, J. Differences in spatiotemporal parameters between trained runners and untrained participants. J Strength Cond Res 31(8): 2169-2175, 2017-The aim of this study was to compare the spatiotemporal parameters of trained runners and untrained participants with the same foot strike pattern (rearfoot) during running at controlled speeds. Twenty-one participants were classified in 2 groups according to their training experience: Trained (n = 10, amateur runners with long distance training experience) and Untrained (n = 11, healthy untrained participants)...
August 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28731758/noncontact-cohesive-swimming-of-bacteria-in-two-dimensional-liquid-films
#15
Ye Li, He Zhai, Sandra Sanchez, Daniel B Kearns, Yilin Wu
Bacterial swimming in confined two-dimensional environments is ubiquitous in nature and in clinical settings. Characterizing individual interactions between swimming bacteria in 2D confinement will help to understand diverse microbial processes, such as bacterial swarming and biofilm formation. Here we report a novel motion pattern displayed by flagellated bacteria in 2D confinement: When two nearby cells align their moving directions, they tend to engage in cohesive swimming without direct cell body contact, as a result of hydrodynamic interaction but not flagellar intertwining...
July 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28730624/prevalence-of-nickel-allergy-in-europe-following-the-eu-nickel-directive%C3%A2-%C3%A2-a-review
#16
REVIEW
Malin G Ahlström, Jacob P Thyssen, Torkil Menné, Jeanne D Johansen
Nickel contact allergy remains a problem in EU countries, despite the EU Nickel Directive. To study the prevalence of nickel allergy in EU countries following the implementation of the EU Nickel Directive, we performed a systematic search in PubMed for studies that examined the prevalence of nickel allergy in EU countries published during 2005-2016. We identified 46 studies: 10 in the general population and 36 in patch tested dermatitis patients. A significantly lower prevalence of nickel allergy after than before the implementation of the EU Nickel Directive was found in women aged 18-35 years (11...
July 21, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28729931/validity-and-reliability-of-the-catwalk-system-as-a-static-and-dynamic-gait-analysis-tool-for-the-assessment-of-functional-nerve-recovery-in-small-animal-models
#17
Elisabeth A Kappos, Patricia K Sieber, Patricia E Engels, Alessio V Mariolo, Salvatore D'Arpa, Dirk J Schaefer, Daniel F Kalbermatten
INTRODUCTION: A range of behavioral testing paradigms have been developed for the research of central and peripheral nerve injuries with the help of small animal models. Following any nerve repair strategy, improved functional outcome may be the most important evidence of axon regeneration. A novel automated gait analysis system, the CatWalk(™), can measure dynamic as well as static gait patterns of small animals. Of most interest in detecting functional recovery are in particular dynamic gait parameters, coordination measures, and the intensity of the animals paw prints...
July 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28729738/human-hippocampal-pre-activation-predicts-behavior
#18
Anna Jafarpour, Vitoria Piai, Jack J Lin, Robert T Knight
The response to an upcoming salient event is accelerated when the event is expected given the preceding events - i.e. a temporal context effect. For example, naming a picture following a strongly constraining temporal context is faster than naming a picture after a weakly constraining temporal context. We used sentences as naturalistic stimuli to manipulate expectations on upcoming pictures without prior training. Here, using intracranial recordings from the human hippocampus we found more power in the high-frequency band prior to high-expected pictures than weakly expected ones...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28729128/rosettes-engrailed-edges-and-star-shaped-patterns-between-rediscovery-and-forgetfulness-in-the-early-accounts-of-vibrating-liquid-drops-floating-over-hot-surfaces
#19
Seán M Stewart
Small drops of liquid brought into contact with very hot surfaces float above it as beautiful, slightly flattened spheroids without coming to the boil. An example of film boiling, drops that are sessile can often suddenly and quite unexpectedly start to oscillate forming highly symmetric patterns of surprising pulchritude. The rim of these oscillating drops take on "star-shaped" patterns with many different modes of vibration possible. Still an object of study today, their discovery, early accounts, rediscovery and ensuing controversies over claims of priority, before quietly slipping away from the collective memory of the scientific community to become all but forgotten makes for a compelling story in the early history of film boiling...
July 17, 2017: Endeavour
https://www.readbyqxmd.com/read/28728969/a-nanoporous-titanium-surface-promotes-the-maturation-of-focal-adhesions-and-the-formation-of-filopodia-with-distinctive-nanoscale-protrusions-by-osteogenic-cells
#20
Dainelys Guadarrama Bello, Aurélien Fouillen, Antonella Badia, Antonio Nanci
While topography is a key determinant of the cellular response to biomaterials the mechanisms implicated in the cell-surface interactions are complex and still not fully elucidated. In this context, we have examined the effect of nanoscale topography on the formation of filopodia, focal adhesions, and on gene expression of proteins associated with cell adhesion and sensing. Commercially pure titanium discs were treated for oxidative nanopatterning with a solution of H2SO4/H2O2 50:50 (v/v). Scanning electron microscopy and atomic force microscopy characterizations showed that this facile chemical treatment efficiently creates a unique nanoporous surface with a root-mean-square roughness of 11...
July 17, 2017: Acta Biomaterialia
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