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https://www.readbyqxmd.com/read/28937925/effect-of-self-reported-distress-thermometer-score-on-the-maximal-handgrip-and-pinch-strength-measurements-in-hemodialysis-patients
#1
Stephanie Camilleri, Stephanie Chong, Kamonwan Tangvoraphonkchai, Suree Yoowannakul, Andrew Davenport
BACKGROUND: Muscle weakness is a risk factor for mortality in hemodialysis (HD) patients. Muscle strength measurements are routinely used as a screening tool but depend on patient cooperation and motivation. We wished to determine whether measuring maximal voluntary muscle strength was affected by patient self-reported distress. METHODS: We measured pinch strength (PS) and handgrip strength (HGS) in 382 adult HD patients with a corresponding self-reported distress thermometer (DT) scores...
October 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28932899/voluntary-running-enhanced-synaptic-plasticity-learning-and-memory-are-mediated-by-notch1-signal-pathway-in-c57bl-mice
#2
Xiaochen Zhang, Chunxiao Yang, Jing Gao, Hongqiang Yin, Hui Zhang, Tao Zhang, Zhuo Yang
It is well known that voluntary running can enhance synaptic plasticity and improve learning and memory abilities. The Notch1 receptor is also reported to be associated with these processes, but its role in running-induced alterations is unclear. In this study, we aimed to investigate whether the Notch1 signalling pathway was involved in voluntary running-induced enhancement of synaptic plasticity, learning and memory. Notch1 heterozygous deficient (Notch1(+/-)) mice and wildtype (WT) C57BL littermates were randomly divided into runner group and non-runner group...
September 20, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28932611/chronic-pelvic-pain-and-infertility-resulting-from-unrecognized-retained-laminaria
#3
Wesley Nilsson, Sasha Mikhael, Jennifer Kaplan
BACKGROUND: In 2013, the abortion rate in the United States was found to be 200 abortions per 1,000 live births. Of these, the CDC estimates that nearly 49% were performed using unsafe measures. Even when these procedures are safely performed, patients are at risk for immediate or delayed complications. In second-trimester terminations, mechanical dilation with an osmotic dilator is common to allow for delivery of the fetus. The Japanese seaweed Laminaria japonica is used to achieve this purpose...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28930822/five-years-experience-on-3-4-diaminopyridine-phosphate-in-lambert-eaton-syndrome-case-reports
#4
Simona Portaro, Teresa Brizzi, Stefano Sinicropi, Alberto Cacciola, Maria Cristina De Cola, Alessia Bramanti, Demetrio Milardi, Antonino Lupica, Placido Bramanti, Antonio Toscano, Carmelo Rodolico
RATIONALE: To report our experience on 7 patients (4 males and 3 females), affected by nonparaneoplastic Lambert-Eaton myasthenic syndrome, treated with 3,4-diaminopyridine phosphate (3,4-DAPP) either alone or in combination with other immunosuppressants or steroids. PATIENT CONCERNS: Patients have been evaluated at specific timepoints (ie, baseline and last 5 year follow-up), with neurological examination, autoantibodies against presynaptic voltage-gated Cav2.1 (P/Q type) calcium ion channel (VGCC) dosage, neurophysiological evaluation focusing on the increased amplitude of the compound muscle action potential (cMAP) after maximum voluntary effort, quantitative myasthenia gravis (QMG) and activities of daily living scales, and autonomic nervous system involvement evaluation...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28929907/management-of-obesity-after-spinal-cord-injury-a-systematic-review
#5
M H Shojaei, S M Alaviniaa, B C Craven
CONTEXT: Individuals with chronic spinal cord injury (SCI) are susceptible to central and visceral obesity and it's metabolic consequences; consensus based guidelines for obesity management after SCI have not yet been stablished. OBJECTIVES: To identify and compare effective means of obesity management among SCI individuals. METHODS: This systematic review included English and non-English articles, published prior to April 2017 found in the PubMed/Medline, Embase, CINAHL Psychinfo and Cochrane databases...
September 20, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28929523/follow-up-protocol-was-useful-for-children-whose-parents-attended-emergency-departments-after-partner-violence-substance-abuse-or-a-suicide-attempt
#6
Eva M M Hoytema van Konijnenburg, Maj Gigengack, Arianne H Teeuw, Tessa Sieswerda-Hoogendoorn, Sonja N Brilleslijper-Kater, Boudien C Flapper, Ramón J L Lindauer, Johannes B van Goudoever, Johanna H van der Lee
AIM: This was a one-year follow up of families referred to support services after the parents visited the emergency department due to intimate partner violence, substance abuse or a suicide attempt. Its aim was to evaluate the wellbeing of any children. METHODS: Data on families identified a year earlier by the Amsterdam Protocol were gathered from child protective services and parent and child self-reports in two Dutch regions from 2012-2015. RESULTS: We included 399 children (52%) boys with a median age of eight years (range 1-18) in the study using child protective services data...
September 19, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28928181/development-of-core-outcome-sets-for-effectiveness-trials-of-interventions-to-prevent-and-or-treat-delirium-del-cors-study-protocol
#7
Louise Rose, Meera Agar, Lisa D Burry, Noll Campbell, Mike Clarke, Jacques Lee, Najma Siddiqi, Valerie J Page
INTRODUCTION: Delirium is a common, serious and potentially preventable condition with devastating impact on the quality of life prompting a proliferation of interventional trials. Core outcome sets aim to standardise outcome reporting by identifying outcomes perceived fundamental for measurement in trials of a specific interest area. Our aim is to develop international consensus on two core outcome sets for trials of interventions to prevent and/or treat delirium, irrespective of study population...
September 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28926614/effect-of-chronic-stress-on-running-wheel-activity-in-mice
#8
Evan DeVallance, Dale Riggs, Barbara Jackson, Travis Parkulo, Stanley Zaslau, Paul D Chantler, I Mark Olfert, Randy W Bryner
Acute and chronic stress have been reported to have differing effects on physical activity in rodents, but no study has examined a chronic stress protocol that incorporates stressors often experienced by rodents throughout a day. To examine this, the effects of the Unpredictable Chronic Mild Stress (UCMS) protocol on voluntary running wheel activity at multiple time points, and/or in response to acute removal of chronic stress was determined. Twenty male Balb/c mice were given access and accustomed to running wheels for 4 weeks, after which they were randomized into 2 groups; exercise (EX, n = 10) and exercise with chronic stress using a modified UCMS protocol for 7 hours/day (8:00 a...
2017: PloS One
https://www.readbyqxmd.com/read/28924063/adolescent-and-young-adult-tattooing-piercing-and-scarification
#9
Cora C Breuner, David A Levine
Tattoos, piercing, and scarification are now commonplace among adolescents and young adults. This first clinical report from the American Academy of Pediatrics on voluntary body modification will review the methods used to perform the modifications. Complications resulting from body modification methods, although not common, are discussed to provide the pediatrician with management information. Body modification will be contrasted with nonsuicidal self-injury. When available, information also is presented on societal perceptions of body modification...
September 18, 2017: Pediatrics
https://www.readbyqxmd.com/read/28923336/-sexual-behaviour-and-human-immunodeficiency-virus-testing-in-university-students-from-cuzco-peru
#10
M Paz Bermúdez, M Teresa Ramiro, Inmaculada Teva, Tamara Ramiro-Sánchez, Gualberto Buela-Casal
OBJECTIVE: To analyse sexual behaviour, HIV testing, HIV testing intentions and reasons for not testing for HIV in university students from Cuzco (Peru). METHODS: The sample comprised 1,377 university students from several institutions from Cuzco (Peru). The size of the sample was set according to a maximum 3% error estimation and a 97% confidence interval. Ages ranged from 16 to 30 years old. The data were collected through a self-administered, anonymous and voluntary questionnaire regarding sexual behaviour and HIV testing...
September 15, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28921678/ipsilateral-corticotectal-projections-from-the-primary-premotor-and-supplementary-motor-cortical-areas-in-adult-macaque-monkeys-a-quantitative-anterograde-tracing-study
#11
Michela Fregosi, Eric M Rouiller
The corticotectal projection from cortical motor areas is one of several descending pathways involved in the indirect control of spinal motoneurons. In non-human primates, previous studies reported that cortical projections to the superior colliculus originated from the premotor cortex and the primary motor cortex, whereas no projection originated from the supplementary motor area. The aim of the present study was to investigate and compare the properties of corticotectal projections originating from these three cortical motor areas in intact adult macaques (n=9)...
September 18, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28919821/prevalence-of-fertility-desire-and-its-associated-factors-among-15-to-49-year-old-people-living-with-hiv-aids-in-addis-ababa-ethiopia-a-cross-sectional-study-design
#12
Takele Menna Adilo, Hirut Megerssa Wordofa
BACKGROUND: The magnitude of unprotected sex to satisfy the desire for fertility among people living with HIV/AIDS (PLHIV) may rise more due to the availability of antiretroviral therapy (ART) in most HIV-affected countries. This could, however, have the risk of passing on HIV to sexual partners and children. The aim of this study, therefore, was to determine the magnitude and factors associated with the fertility desire of reproductive-age PLHIV in Addis Ababa, Ethiopia, for research-based and timely actions...
2017: HIV/AIDS: Research and Palliative Care
https://www.readbyqxmd.com/read/28919147/pediatric-resident-training-in-prepubertal-vulvar-conditions
#13
Monica Rosen, Veronica I Alaniz, Emily K Kobernik, Stephanie Booms, Yolanda R Smith, Elisabeth H Quint
STUDY OBJECTIVE: To assess pediatric resident training in diagnosing and managing prepubertal gynecologic conditions. DESIGN: Voluntary 32-question survey emailed to participants. SETTING: Email contact through the American Academy of Pediatrics listserve. PARTICIPANTS: 7075 U.S. pediatrics and combined internal medicine-pediatric residents. INTERVENTIONS: Descriptive analysis including Chi-square tests was performed on survey results...
September 14, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28918414/a-protocol-of-a-cross-sectional-study-evaluating-an-online-tool-for-early-career-peer-reviewers-assessing-reports-of-randomised-controlled-trials
#14
Anthony Chauvin, David Moher, Doug Altman, David L Schriger, Sabina Alam, Sally Hopewell, Daniel R Shanahan, Alessandro Recchioni, Philippe Ravaud, Isabelle Boutron
INTRODUCTION: Systematic reviews evaluating the impact of interventions to improve the quality of peer review for biomedical publications highlighted that interventions were limited and have little impact. This study aims to compare the accuracy of early career peer reviewers who use an innovative online tool to the usual peer reviewer process in evaluating the completeness of reporting and switched primary outcomes in completed reports. METHODS AND ANALYSIS: This is a cross-sectional study of individual two-arm parallel-group randomised controlled trials (RCTs) published in the BioMed Central series medical journals, BMJ, BMJ Open and Annals of Emergency Medicine and indexed with the publication type 'Randomised Controlled Trial'...
September 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28917241/dietary-sodium-reduction-in-new-zealand-influence-of-the-tick-label
#15
Sherry X Ning, Louise A Mainvil, Rachel K Thomson, Rachel M McLean
BACKGROUND AND OBJECTIVES: The Tick programme of the National Heart Foundation (NHF) is the longest standing voluntary front of pack signpost nutrition logo in New Zealand. It provides a platform for collaboration with the food industry to encourage development of healthier products. This study evaluated the impact of the Tick programme on sodium in processed food. METHODS AND STUDY DESIGN: Fifty-two Tick programme products from food categories known to contribute substantially to sodium intake were identified...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28905498/effect-of-bimagrumab-on-thigh-muscle-volume-and-composition-in-men-with-casting-induced-atrophy
#16
Daniel S Rooks, Didier Laurent, Jens Praestgaard, Scott Rasmussen, Michael Bartlett, László B Tankó
BACKGROUND: Patients experiencing disuse atrophy report acute loss of skeletal muscle mass which subsequently leads to loss of strength and physical capacity. In such patients, especially the elderly, complete recovery remains a challenge even with improved nutrition and resistance exercise. This study aimed to explore the clinical potential of bimagrumab, a human monoclonal antibody targeting the activin type II receptor, for the recovery of skeletal muscle volume from disuse atrophy using an experimental model of lower extremity immobilization...
September 14, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28902863/identification-of-vaccine-derived-rotavirus-strains-in-children-with-acute-gastroenteritis-in-japan-2012-2015
#17
Mei Kaneko, Sayaka Takanashi, Aksara Thongprachum, Nozomu Hanaoka, Tsuguto Fujimoto, Koo Nagasawa, Hirokazu Kimura, Shoko Okitsu, Masashi Mizuguchi, Hiroshi Ushijima
Two live attenuated oral rotavirus vaccines, Rotarix and RotaTeq, have been introduced as voluntary vaccination in Japan since 2011 and 2012, respectively. Effectiveness of the vaccines has been confirmed, whereas concerns such as shedding of the vaccine strains and gastroenteritis cases caused by vaccine strains are not well assessed. We aimed to identify the vaccine strains in children with acute gastroenteritis (AGE) to investigate the prevalence of AGE caused by vaccination or horizontal transmission of vaccine strains...
2017: PloS One
https://www.readbyqxmd.com/read/28900757/low-incidence-of-postoperative-urinary-retention-with-the-use-of-a-nurse-led-bladder-scan-protocol-after-hip-and-knee-arthroplasty-a-retrospective-cohort-study
#18
N P Kort, Y Bemelmans, R Vos, M G M Schotanus
PURPOSE: Postoperative urinary retention (POUR), defined as the inability to empty the bladder voluntary after surgery, is a commonly reported complication. This study reports the incidence and possible risk factors for POUR after elective fast-track hip or knee arthroplasty when using a nurse-led bladder scan protocol. METHODS: This retrospective cohort study included data from 803 patients who underwent unilateral hip or knee arthroplasty. Patients' digital clinical records were reviewed for eligibility...
September 12, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28900560/building-a-better-gluteal-bridge-electromyographic-analysis-of-hip-muscle-activity-during-modified-single-leg-bridges
#19
B J Lehecka, Michael Edwards, Ryan Haverkamp, Lani Martin, Kambry Porter, Kailey Thach, Richard J Sack, Nils A Hakansson
BACKGROUND: Gluteal strength plays a role in injury prevention, normal gait patterns, eliminating pain, and enhancing athletic performance. Research shows high gluteal muscle activity during a single-leg bridge compared to other gluteal strengthening exercises; however, prior studies have primarily measured muscle activity with the active lower extremity starting in 90 ° of knee flexion with an extended contralateral knee. This standard position has caused reports of hamstring cramping, which may impede optimal gluteal strengthening...
August 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28898876/filing-sources-after-oral-p2y12-platelet-inhibitors-to-the-food-and-drug-administration-adverse-event-reporting-system-faers
#20
Victor L Serebruany, Vasily Cherepanov, Moo Hyun Kim, Oleg Litvinov, Hector A Cabrera-Fuentes, Thomas A Marciniak
BACKGROUND: The US Food and Drug Administration Adverse Event Reporting System (FAERS) is a global passive surveillance database that relies on voluntary reporting by health care professionals and consumers as well as required mandatory reporting by pharmaceutical manufacturers. However, the initial filers and comparative patterns for oral P2Y12 platelet inhibitor reporting are unknown. We assessed who generated original FAERS reports for clopidogrel, prasugrel, and ticagrelor in 2015...
September 13, 2017: Cardiology
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