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antibiotic bronchitis

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https://www.readbyqxmd.com/read/28107288/effects-of-infant-formula-with-human-milk-oligosaccharides-on-growth-and-morbidity-a-randomized-multicenter-trial
#1
Giuseppe Puccio, Philippe Alliet, Cinzia Cajozzo, Elke Janssens, Giovanni Corsello, Norbert Sprenger, Susan Wernimont, Delphine Egli, Laura Gosoniu, Philippe Steenhout
OBJECTIVES: We evaluated effects of infant formula supplemented with 2 human milk oligosaccharides (HMOs) on infant growth, tolerance and morbidity. METHODS: Healthy infants, 0-14 days old, were randomized to an intact-protein, cow's-milk-based infant formula (Control, n = 87) or the same formula with 1.0 g/L 2'fucosyllactose (2'FL) and 0.5 g/L lacto-N-neotetraose (LNnT) (Test, n = 88) from enrollment to 6 months; all infants received standard follow-up formula without HMOs from 6-12 months...
January 20, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28097718/a-prospective-study-of-the-use-of-antibiotics-in-the-emergency-department-of-a-chinese-university-hospital
#2
Linan Zeng, Die Hu, Imti Choonara, Dezhi Mu, Lingli Zhang, Xihong Li, Zuojie Zhang, Zhiqiang Hu, Shuyan Quan
BACKGROUND: Antibiotics are one of the most widely misused group of medicines. The aim of this study was to investigate the use of antibiotics in one of the paediatric emergency departments in China. METHODS: We performed a prospective, cross-sectional study of antibiotic use in the paediatric emergency room of West China Second University Hospital. A total of 500 consecutive patients from March 25 to April 3 2013 were included. Clinical details of the patients were also collected in order to analyse antibiotic use...
February 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28096997/bronchial-tree-shaped-mucous-plug-in-cystic-fibrosis-imaging-guided-management
#3
Ignazio Salamone, Baldassare Mondello, Maria Cristina Lucanto, Simona Cristadoro, Mariangela Lombardo, Mario Barone
We report the case of a 17-year-old boy with cystic fibrosis (CF) who presented with persistent cough; after starting intravenous antibiotics for Pseudomonas aeruginosa he underwent a computed tomography (CT) scan of the chest. CT revealed extensive consolidation in the right lower lobe with relative bronchus obstruction; the cause of bronchial obstruction was detected in the mediastinal window, corresponding to a bronchial tree-shaped, thick, tenacious mucous plug. This was extracted 48 h after unresponsive bronchial washing and endobronchial instillation of rhDNAse, using foreign-body forceps, with subsequent resolution of cough...
March 2017: Respirology Case Reports
https://www.readbyqxmd.com/read/28092467/early-investigational-antibiotics-for-the-treatment-of-acute-exacerbations-of-chronic-bronchitis
#4
Matthew E Falagas, Maria Georgiou
Acute exacerbations in patients with chronic bronchitis are a leading cause of hospitalizations and death. Bacteria contribute significantly to such exacerbations. The aim of this review was to explore the potential role of investigational antibiotics in the treatment of these episodes. Areas covered: The available literature in PubMed database, in websites related to investigational drugs and in websites of the producing companies has been searched. The in vitro activity against pathogens involved in acute exacerbations of chronic bronchitis and the pharmacokinetic profile of antibiotics currently under development were taken into consideration for inclusion in the review...
January 16, 2017: Expert Opinion on Investigational Drugs
https://www.readbyqxmd.com/read/28018766/differentiation-of-lung-cancer-empyema-and-abscess-through-the-investigation-of-a-dry-cough
#5
Brittany Urso, Scott Michaels
An acute dry cough results commonly from bronchitis or pneumonia. When a patient presents with signs of infection, respiratory crackles, and a positive chest radiograph, the diagnosis of pneumonia is more common. Antibiotic failure in a patient being treated for community-acquired pneumonia requires further investigation through chest computed tomography. If a lung mass is found on chest computed tomography, lung empyema, abscess, and cancer need to be included on the differential and managed aggressively. This report describes a 55-year-old Caucasian male, with a history of obesity, recovered alcoholism, hypercholesterolemia, and hypertension, presenting with an acute dry cough in the primary care setting...
November 24, 2016: Curēus
https://www.readbyqxmd.com/read/27996026/public-reporting-as-a-prescriptions-quality-improvement-measure-in-primary-care-settings-in-china-variations-in-effects-associated-with-diagnoses
#6
Yuqing Tang, Chaojie Liu, Xinping Zhang
The overprovision and irrational use of antibiotics and injections are a major public health concern. Public reporting has been adopted as a strategy to encourage good prescribing practices. This study evaluated the effects of public reporting on antibiotic and injection prescriptions in urban and rural primary care settings in Hubei province, China. A randomized control trial was conducted, with 10 primary care institutions being subject to public reporting and another 10 serving as controls. Prescription indicators were publicly reported monthly over a one-year period...
December 20, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27959904/clinical-features-and-outcomes-of-ipf-patients-hospitalized-for-pulmonary-infection-a-japanese-cohort-study
#7
Ryo Yamazaki, Osamu Nishiyama, Hiroyuki Sano, Takashi Iwanaga, Yuji Higashimoto, Hiroaki Kume, Yuji Tohda
Many patients with idiopathic pulmonary fibrosis (IPF) undergo hospitalizations due to pulmonary infections. We retrospectively investigated the characteristics of hospitalizations due to pulmonary infection in patients with IPF to elucidate causative pathogens and mortality. We reviewed patients with IPF who were admitted between January 2008 and December 2014 for pulmonary infections including pneumonia and bronchitis. The causative pathogen, the relationship between the site of pneumonia and existing IPF radiological patterns on high-resolution chest CT, and predictors of mortality were evaluated...
2016: PloS One
https://www.readbyqxmd.com/read/27941112/antisynthetase-syndrome-ass-presenting-as-acute-respiratory-distress-syndrome-ards-in-a-patient-without-myositis-features
#8
Venkat Kiran Kanchustambham, Swetha Saladi, Sarah Mahmoudassaf, Setu Patolia
A woman aged 61 years presented to the emergency room with a 1-week history of dyspnoea on exertion and dry cough. X-ray of the chest showed diffuse interstitial opacities and was started on antibiotics and furosemide, and despite these measures, patient's respiratory status worsened, prompting endotracheal intubation. CT of the chest showed diffuse bilateral ground glass opacities and underwent bronchoscope with trans-bronchial biopsy that showed chronic bronchitis. Pt was empirically started on intravenous steroids due to concerns for interstitial lung disease (ILD)...
December 9, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27929206/acute-bronchitis
#9
Scott Kinkade, Natalie A Long
Cough is the most common illness-related reason for ambulatory care visits in the United States. Acute bronchitis is a clinical diagnosis characterized by cough due to acute inflammation of the trachea and large airways without evidence of pneumonia. Pneumonia should be suspected in patients with tachypnea, tachycardia, dyspnea, or lung findings suggestive of pneumonia, and radiography is warranted. Pertussis should be suspected in patients with cough persisting for more than two weeks that is accompanied by symptoms such as paroxysmal cough, whooping cough, and post-tussive emesis, or recent pertussis exposure...
October 1, 2016: American Family Physician
https://www.readbyqxmd.com/read/27922232/changing-epidemiology-of-non-cystic-fibrosis-bronchiectasis
#10
Semiha Bahçeci, Sait Karaman, Hikmet Tekin Nacaroğlu, Selçuk Yazıcı, Saniye Girit, Şule Ünsal-Karkıner, Demet Can
Non-cystic fibrosis bronchiectasis again becomes a major health problem due to inappropriate antibiotic use and increasing frequency of protracted bacterial bronchitis. The aim was to determine the changes in etiology of bronchiectasis. Patients who admitted to Behçet Uz Children Hospital between 2005 and 2015 (n=110) were retrospectively examined. The etiology of bronchiectasis was detected as; primary ciliary dyskinesia 26.4%, protracted bacterial bronchitis 22.8%, primary immune deficiency 11.8%, bronchiolitis obliterans 8...
2016: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/27920515/effect-of-elom-080-on-exacerbations-and-symptoms-in-copd-patients-with-a-chronic-bronchitis-phenotype-a-post-hoc-analysis-of-a-randomized-double-blind-placebo-controlled-clinical-trial
#11
Kai-Michael Beeh, Jutta Beier, Henning Candler, Thomas Wittig
BACKGROUND: Treating symptoms and preventing exacerbations are key components of chronic obstructive pulmonary disease (COPD) long-term management. Recently, a more tailored treatment approach has been proposed, in particular for two well-established clinical phenotypes, frequent exacerbators and chronic bronchitis-dominant COPD. ELOM-080 has demonstrated clinical efficacy in treating symptoms and preventing exacerbations in subjects with chronic bronchitis. However, little is known about the potential effects of ELOM-080 in COPD patients...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27911082/necrotizing-and-haemorrhagic-hepatitis-and-enteritis-in-commercial-layer-pullets
#12
Yuko Sato, William L Wigle, Tsang Long Lin, Eric Gingerich, Patricia S Wakenell
This case report describes an episode of recurring severe necrotizing and haemorrhagic hepatitis and enteritis experienced in a flock of commercial layer pullets at 12 weeks of age and again at 18 weeks of age in Indiana. Pullets had been vaccinated at 10 weeks old using a trivalent Salmonella Enteritidis (SE)/Newcastle disease/infectious bronchitis oil-emulsion-inactivated vaccine. The pullets were found dead at 12 weeks with firm but friable, enlarged, haemorrhagic livers, enlarged spleens, and necrohaemorrhagic intestines...
February 2017: Avian Pathology: Journal of the W.V.P.A
https://www.readbyqxmd.com/read/27887585/reduction-in-antibiotic-prescribing-for-respiratory-tract-infections-in-swedish-primary-care-a-retrospective-study-of-electronic-patient-records
#13
Mia Tyrstrup, Anders Beckman, Sigvard Mölstad, Sven Engström, Christina Lannering, Eva Melander, Katarina Hedin
BACKGROUND: Swedish studies on antibiotic use in primary care have been based on one-week registrations of infections. In order to study adherence to guidelines, analyses based on large databases that provide information on diagnosis linked prescriptions, are needed. This study describes trends in management of infections in Swedish primary care particularly with regards to antibiotic prescribing and adherence to national guidelines. METHODS: A descriptive study of Sweden's largest database regarding diagnosis linked antibiotic prescription data, the Primary care Record of Infections in Sweden (PRIS), for the years 2008, 2010 and 2013...
November 25, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27883116/zabofloxacin-for-chronic-bronchitis
#14
B Kocsis, D Szabo
Treatment of lower respiratory tract infection poses as an ongoing challenge among respiratory tract diseases. Bacterial infections are causes of acute exacerbations in chronic bronchitis and indications for antibacterial therapy. Several antibiotics were applied to treat bacterial infections in chronic bronchitis, among them fluoroquinolones are considered potent, broad-spectrum agents with excellent tissue penetration. This monograph focuses on zabofloxacin, a novel fluoroquinolone agent recently approved and launched in South Korea, and summarizes the drug's antibacterial efficacy, pharmacokinetic properties and toxicity...
September 2016: Drugs of Today
https://www.readbyqxmd.com/read/27812804/paediatric-antibiotic-prescriptions-in-primary-care-in-the-alpes-maritimes-area-of-southeastern-france-between-2008-and-2013
#15
P Touboul-Lundgren, P Bruno, L Bailly, B Dunais, C Pradier
France has remained among the top five European countries for ambulatory antibiotic consumption since such monitoring began in 1998. Young children are major antibiotic consumers, in spite of the viral origin of most infections in this population. Recommendations were updated in 2011 to limit prescriptions. In order to assess their impact, diagnoses and prescriptions were compared in a population of children attending daycare centres in southeastern France in 2008 and 2012. Trends in the reimbursement of paediatric antibiotic prescriptions by the national health insurance (NHI) for the whole area were also studied...
November 3, 2016: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/27792075/reducing-inappropriate-antibiotic-prescribing-for-adults-with-acute-bronchitis-in-an-urgent-care-setting-a-quality-improvement-initiative
#16
Tamara L Link, Mary L Townsend, Eugene Leung, Sekhar Kommu, Rhonda Y Vega, Cristina C Hendrix
Acute bronchitis is a predominantly viral illness and, according to clinical practice guidelines, should not be treated with antibiotics. Despite clear guidelines, acute bronchitis continues to be the most common acute respiratory illness for which antibiotics are incorrectly prescribed. Although the national benchmark for antibiotic prescribing for adults with acute bronchitis is 0%, a preliminary record review before implementing the intervention at the project setting showed that 96% (N = 30) of adults with acute bronchitis in this setting were prescribed an antibiotic...
October 2016: Advanced Emergency Nursing Journal
https://www.readbyqxmd.com/read/27788254/microorganisms-causing-community-acquired-acute-bronchitis-the-role-of-bacterial-infection
#17
Ji Young Park, Sunghoon Park, Sun Hwa Lee, Myung Goo Lee, Yong Bum Park, Kil Chan Oh, Jae-Myung Lee, Do Il Kim, Ki-Hyun Seo, Kyeong-Cheol Shin, Kwang Ha Yoo, Yongchun Ko, Seung Hun Jang, Ki-Suck Jung, Yong Il Hwang
BACKGROUND: Although acute bronchitis is quite common, there is relatively limited information regarding the microorganisms that are involved in this illness. METHODS: We performed a prospective study of acute bronchitis at 31 hospitals and clinics in Korea from July 2011 to June 2012. Sputum specimens were collected for polymerase chain reaction (PCR) and culture of microorganisms. RESULTS: Of the 811 enrolled patients, 291 had acceptable sputum specimens that were included for analysis of the etiologic distribution...
2016: PloS One
https://www.readbyqxmd.com/read/27747036/extensive-plastic-bronchitis-etiology-of-a-rare-condition
#18
Norbert Garcia-Henriquez, Eric M Toloza, Farah Khalil, Maria F Echavarria, Joseph R Garrett, Carla C Moodie, Frank J Kaszuba, Jacques P Fontaine
We present the case of a 55-year-old man who developed extensive occlusive bronchial casts after trachea-esophageal (TE) fistula repair. The bronchial casts were treated by bronchoscopic extraction, high dose steroids, antibiotics, and antifungals. Despite this multi-modality treatment, the rapid formation of these occlusive bronchial casts was very aggressive and could not be controlled even with a series of five rigid bronchoscopic extractions within a 48-hour period. The patient quickly deteriorated and succumbed to the inflammatory state...
September 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27734780/-is-procalcitonin-measurement-useful-in-managing-respiratory-tract-infections
#19
J M Prins, T van der Poll
Better use of current antibiotics is warranted to curb increasing antimicrobial resistance rates. Procalcitonin guidance can safely reduce antibiotic usage when used to initiate or discontinue antibiotics in adult patients with a respiratory tract infection. However, the claimed reductions in antibiotic usage are mainly achieved in patients with acute bronchitis and exacerbations of COPD, conditions for which guidelines already discourage antibiotic treatment. Sequential procalcitonin measurements can also reduce the treatment duration of community-acquired pneumonia from 10-12 to 5-7 days, which is, however, already the recommended treatment duration for in- and outpatients under the current Dutch guidelines...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27708777/cough-impact-beliefs-and-expectations-from-a-national-survey
#20
Roberto W Dal Negro, Massimiliano Mazzolini, Paola Turco, Alessandro Zanasi
BACKGROUND: Cough is one of the most common discomforts affecting general population, which can disrupt subjects' quality of life due to its physical, social, and psychological effects. Aim of the study was to investigate the impact of cough and related beliefs of general population. METHODS: A cross-sectional telephone survey was carried out by means of a specific, validated questionnaire on a representative sample of Italian general population. All the interviews were carried out according to the Computer Assisted Telephone Interview (CATI) methodology by expert, professional interviewers...
2016: Multidisciplinary Respiratory Medicine
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