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https://www.readbyqxmd.com/read/28812940/odontogenic-orbital-abscess-with-intracranial-and-pulmonary-involvement
#1
E Hughes, N Wynne, S Quinn, T Fulcher
A 58-year-old woman presented to the emergency department with left ptosis and complete ophthalmoplegia. Imaging demonstrated a left orbital abscess. Her past medical history included cavitatory lung disease and "aseptic" meningitis 2 months previously. An anaerobic organism and commensal of the oral flora, Peptostreptococcus sp., was cultured from the orbital abscess. The patient was found to have a carious upper molar with chronic buccal abscess, which was extracted. This case presents an uncommon pathogen arising from an odontogenic infection as the etiology for orbital abscess, cavitatory lung disease, and meningitis in one patient...
August 16, 2017: Orbit
https://www.readbyqxmd.com/read/28801480/gfi1-functions-in-transcriptional-control-and-cell-fate-determination-require-snag-domain-methylation-to-recruit-lsd1
#2
Matthew Velinder, Jason Singer, Diana Bareyan, Jessica Meznarich, Christopher M Tracy, James M Fulcher, David McClellan, Helena Lucente, Sarah Franklin, Sunil Sharma, Michael E Engel
No abstract text is available yet for this article.
August 11, 2017: Biochemical Journal
https://www.readbyqxmd.com/read/28789533/weak-temperature-dependence-of-ageing-of-structural-properties-in-atomistic-model-glassformers
#3
Thomas Jenkinson, Peter Crowther, Francesco Turci, C Patrick Royall
Ageing phenomena are investigated from a structural perspective in two binary Lennard-Jones glassformers, the Kob-Andersen and Wahnström mixtures. In both, the geometric motif assumed by the glassformer upon supercooling, the locally favoured structure (LFS), has been established. The Kob-Andersen mixture forms bicapped square antiprisms; the Wahnström model forms icosahedra. Upon ageing, we find that the structural relaxation time has a time-dependence consistent with a power law. However, the LFS population and potential energy increase and decrease, respectively, in a logarithmic fashion...
August 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28772486/study-of-the-molecular-dynamics-of-multiarm-star-polymers-with-a-poly-ethyleneimine-core-and-poly-lactide-multiarms
#4
Frida Román, Pere Colomer, Yolanda Calventus, John M Hutchinson
Multiarm star polymers, denoted PEIx-PLAy and containing a hyperbranched poly(ethyleneimine) (PEI) core of different molecular weights x and poly(lactide) (PLA) arms with y ratio of lactide repeat units to N links were used in this work. Samples were preconditioned to remove the moisture content and then characterized by thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and dielectric relaxation spectroscopy (DRS). The glass transition temperature, Tg, is between 48 and 50 °C for all the PEIx-PLAy samples...
February 4, 2017: Materials
https://www.readbyqxmd.com/read/28767047/effects-of-cu-doping-on-the-electronic-structure-and-magnetic-properties-of-mnco-sub-2-sub-o-sub-4-sub-nanostructures
#5
Prativa Pramanik, Subhash Thota, Sobhit Singh, Deep Chandra Joshi, Bruno Weise, Anja Waske, Mohindar Seehra
Reported here are results and their analysis from our detailed investigations of the effects of Cu doping (x ≤ 0.20) on the electronic structure and magnetic properties of the spinel MnCo<sub>2</sub>O<sub>4</sub>. Detailed comparison is given for the x = 0 and x = 0.2 cases for both the bulk-like samples and nanoparticles. The electronic structure determined from XPS and Rietveld analysis of XRD patterns shows the structure to be: (Co<sup>3+</sup>)<sub>A</sub>[Mn<sup>3+</sup>Co<sub>(1-x)</sub><sup>2+</sup>Cu<sub>x</sub><sup>2+</sup>]<sub>B</sub>O<sub>4</sub> Cu<sup>2+</sup> substitutes for Co<sup>2+</sup> on the octahedral B-sites...
August 2, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28737797/cation-distribution-dependent-magnetic-properties-in-cocr2-xfexo4-x-0-1-to-0-5-exafs-m%C3%A3-ssbauer-and-magnetic-measurements
#6
D Kumar, A Banerjee, A Mahmoud, Chandana Rath
In this report, we have examined the evolution of the structure and rich magnetic transitions such as a paramagnetic to ferrimagnetic phase transition at the Curie temperature (TC), spiral ordering temperature (TS) and lock-in temperature (TL) observed in the CoCr2O4 spinel multiferroic after substituting Fe. The crystal structure, microstructure and cation distribution among the tetrahedral (A) and octahedral (B) sites in the spinel lattice are characterised by X-ray diffraction, transmission electron microscopy, Extended X-ray Absorption Fine Structure (EXAFS) and Mössbauer spectroscopy...
July 24, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28709319/golf-course-and-funnel-energy-landscapes-protein-folding-concepts-in-martensites
#7
N Shankaraiah
We use protein folding energy landscape concepts such as golf course and funnel to study re-equilibration in athermal martensites under systematic temperature quench Monte Carlo simulations. On quenching below a transition temperature, the seeded high-symmetry parent-phase austenite that converts to the low-symmetry product-phase martensite, through autocatalytic twinning or elastic photocopying, has both rapid conversions and incubation delays in the temperature-time-transformation phase diagram. We find the rapid (incubation delays) conversions at low (high) temperatures arises from the presence of large (small) size of golf-course edge that has the funnel inside for negative energy states...
June 2017: Physical Review. E
https://www.readbyqxmd.com/read/28702622/mechanism-of-ion-transport-in-perfluoropolyether-electrolytes-with-a-lithium-salt
#8
Ksenia Timachova, Mahati Chintapalli, Kevin R Olson, Sue J Mecham, Joseph M DeSimone, Nitash P Balsara
Perfluoropolyethers (PFPEs) are polymer electrolytes with fluorinated carbon backbones that have high flash points and have been shown to exhibit moderate conductivities and high cation transference numbers when mixed with lithium salts. Ion transport in four PFPE electrolytes with different endgroups was characterized by differential scanning calorimetry (DSC), ac impedance, and pulsed-field gradient NMR (PFG-NMR) as a function of salt concentration and temperature. In spite of the chemical similarity of the electrolytes, salt diffusion coefficients measured by PFG-NMR and the glass transition temperature measured by DSC appear to be uncorrelated to ionic conductivity measured by ac impedance...
August 16, 2017: Soft Matter
https://www.readbyqxmd.com/read/28692540/unique-microrna-expression-in-the-colonic-mucosa-during-chronic-hiv-1-infection
#9
Jennifer A Fulcher, Georgios Koukos, Marina Koutsioumpa, Julie Elliott, Alexandra Drakaki, Dimitrios Iliopoulos, Peter A Anton
OBJECTIVE: Chronic HIV-1 infection leads to widespread inflammation and immune dysregulation. The gastrointestinal mucosa, a primary site for HIV-1 replication, is thought to play a significant role in this response. MicroRNAs (miRs) are small non-coding RNAs that regulate gene expression, including immune activation and inflammation. Here we investigate miR expression and function in the colonic mucosa during HIV-1 infection. DESIGN AND METHODS: Using miR profiling, we examined miR expression in the colonic mucosa of HIV-infected subjects...
July 7, 2017: AIDS
https://www.readbyqxmd.com/read/28675539/the-association-between-patient-activation-and-self-care-practices-a-cross-sectional-study-of-an-australian-population-with-comorbid-diabetes-and-chronic-kidney-disease
#10
Edward Zimbudzi, Clement Lo, Sanjeeva Ranasinha, Peter G Kerr, Kevan R Polkinghorne, Helena Teede, Timothy Usherwood, Rowan G Walker, Greg Johnson, Greg Fulcher, Sophia Zoungas
OBJECTIVE: This study aimed to examine the association between performance of self-care activities and patient or disease factors as well as patient activation levels in patients with diabetes and chronic kidney disease (CKD) in Australia. METHODS: A cross-sectional study was conducted among adults with diabetes and CKD (eGFR <60 mL/min/1.73m(2) ) who were recruited from renal and diabetes clinics of four tertiary hospitals in Australia. Demographic and clinical data were collected, as well as responses to the Patient Activation Measure (PAM) and the Summary of Diabetes Self-Care Activities (SDSCA) scale...
July 4, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28664963/dynamical-behavior-of-microgels-of-interpenetrated-polymer-networks
#11
Valentina Nigro, Roberta Angelini, Monica Bertoldo, Fabio Bruni, Maria Antonietta Ricci, Barbara Ruzicka
Microgel suspensions of an interpenetrated Polymer Network (IPN) of PNIPAM and PAAc in D2O have been investigated through dynamic light scattering as a function of temperature, pH and concentration across the Volume Phase Transition (VPT). The dynamics of the system is slowed down under H/D isotopic substitution due to different balance states between polymer/polymer and polymer/solvent interactions suggesting the crucial role played by H-bonding. The swelling behavior, reduced with respect to PNIPAM and water, has been described by the Flory-Rehner theory, tested for PNIPAM microgel and successfully expanded to higher order for IPN microgels...
August 2, 2017: Soft Matter
https://www.readbyqxmd.com/read/28656499/electrical-properties-of-polyetherimide-thin-films-non-parametric-dielectric-response-analysis-with-distribution-of-relaxation-times
#12
Enis Tuncer
High temperature polymeric materials for electrical insulation and energy storage are needed for transformational power applications such as pulsed-power and hybrid electrical vehicles. One of the candidate materials has been polyetherimide, an amorphous thermoplastic with a glass transition over 200 (°)C. Here, the dielectric studies on the material are reported by taking into account the polarization and conduction processes in the polyetherimide. The dielectric data were analyzed with the distribution of relaxation times approach with Debye expression as the kernel in the inversion algorithm, the results then created the relaxation map for polyetherimide...
June 2017: European Physical Journal. E, Soft Matter
https://www.readbyqxmd.com/read/28650511/effect-of-mixed-anions-on-the-physicochemical-properties-of-a-sodium-containing-alkoxyammonium-ionic-liquid-electrolyte
#13
Matthias Hilder, Matthieu Gras, Cameron R Pope, Mega Kar, Douglas R MacFarlane, Maria Forsyth, Luke A O'Dell
The physicochemical properties of the ionic liquid N-ethyl-2-(2-methoxyethoxy)-N,N-bis(2-(2-methoxyethoxy)ethyl)ethan-1-ammonium bis(trifluoromethylsulfonyl)imide (N2(2O2O1)3TFSI) as well as its solutions with sodium bis(trifluoromethylsulfonyl)imide (NaTFSI) and sodium bis(fluorosulfonyl)imide (NaFSI) are compared in order to study the effects of the anion. The NaFSI solutions show weaker interactions as suggested by lower glass transition temperatures, lower densities, lower viscosities and higher conductivities as compared to their more strongly coordinating NaTFSI analogues...
June 26, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28648610/glycan-activation-of-a-sheddase-electrostatic-recognition-between-heparin-and-prommp-7
#14
Yan G Fulcher, Stephen H Prior, Sayaka Masuko, Lingyun Li, Dennis Pu, Fuming Zhang, Robert J Linhardt, Steven R Van Doren
Heparan sulfate proteoglycans activate the matrix metalloproteinase-7 zymogen (proMMP-7) and recruit it in order to shed proteins from cell surfaces. This occurs in uterine and mammary epithelia, bacterial killing, lung healing, and tumor cell signaling. Basic tracks on proMMP-7 recognize polyanionic heparin, according to nuclear magnetic resonance and mutations disruptive of maturation. Contacts and proximity measurements guided docking of a heparin octasaccharide to proMMP-7. The reducing end fits into a basic pocket in the pro-domain while the chain continues toward the catalytic domain...
July 5, 2017: Structure
https://www.readbyqxmd.com/read/28636415/comprehensive-modeling-of-corneal-alkali-injury-in-the-rat-eye
#15
Hosoon Choi, Casie Phillips, Joo Youn Oh, Eileen M Stock, Dong-Ki Kim, Jae-Kyung Won, Samuel Fulcher
PURPOSE: To characterize the molecular, clinical, and histopathological profiles in the rat cornea after alkali injury over a 21-day period. METHODS: Alkali injury was induced in one eye of male Lewis rats. Corneal opacity and corneal neovascularization were assessed daily. Real-time qRT-PCR analysis and immunohistochemical staining were conducted to examine inflammation, neovascularization, and fibrosis. RESULTS: We found that within 2 hours of chemical exposure, corneal opacification rapidly developed with an acute increase in various cytokine expressions, while several cytokines demonstrated a secondary peak by day 7...
June 21, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28621772/high-temperature-spin-glass-like-transition-in-la0-67sr0-33mno3-nanofibers-near-the-curie-point
#16
Ruie Lu, Sen Yang, Yitong Li, Kaiyun Chen, Yun Jiang, Bi Fu, Yin Zhang, Chao Zhou, Minwei Xu, Xuan Zhou
The glassy transition of superparamagnetic (SPM) (r < r0) nanoparticle systems usually occurs at a very low temperature that greatly limits its application to high temperatures. In this work, we report a spin-glass-like (SGL) behavior near the Curie point (TC), i.e., T0 = 330 K, in La0.67Sr0.33MnO3 (LSMO) nanofibers (NFs) composed of nanoparticles beyond the SPM size (r ≫ r0), resulting in a significant increase of the glass transition temperature. This SGL transition near the TC of bulk LSMO can be explained to be the scenario of locally ordered clusters embedded in a disordered host, in which the assembly of nanoparticles has a magnetic core-shell model driven by surface spin glass...
June 28, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28605608/canagliflozin-and-cardiovascular-and-renal-events-in-type-2-diabetes
#17
Bruce Neal, Vlado Perkovic, Kenneth W Mahaffey, Dick de Zeeuw, Greg Fulcher, Ngozi Erondu, Wayne Shaw, Gordon Law, Mehul Desai, David R Matthews
Background Canagliflozin is a sodium-glucose cotransporter 2 inhibitor that reduces glycemia as well as blood pressure, body weight, and albuminuria in people with diabetes. We report the effects of treatment with canagliflozin on cardiovascular, renal, and safety outcomes. Methods The CANVAS Program integrated data from two trials involving a total of 10,142 participants with type 2 diabetes and high cardiovascular risk. Participants in each trial were randomly assigned to receive canagliflozin or placebo and were followed for a mean of 188...
June 12, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28601589/sharpsports-mental-health-awareness-research-project-prevalence-and-risk-factors-of-depressive-symptoms-and-life-stress-in-elite-athletes
#18
Sarah Beable, Mark Fulcher, Arier C Lee, Bruce Hamilton
OBJECTIVES: Our study aims to estimate the prevalence of symptoms of depression and daily life hassles in elite athletes. DESIGN: A cross-sectional prospective epidemiological study design. METHODS: An online anonymous survey was administered during a 2-month period from May to July 2015. Athletes 18 years of age (or older) who were members of the High Performance Sport New Zealand programme were invited to participate. Of 370 potential participants, 187 completed responses were received (51%)...
May 17, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28599995/effects-of-vertical-glottal-duct-length-on-intraglottal-pressures-and-phonation-threshold-pressure-in-the-uniform-glottis
#19
Sheng Li, Ronald C Scherer, Lewis P Fulcher, Xianbo Wang, Lijun Qiu, Mingxi Wan, Supin Wang
According to Titze's 1988 derivations for phonation threshold pressure (PTP), there are a number of important variables that PTP depends upon. A primary one is the vertical glottal duct length T: PTP decreases if T is increased. Changing the length of T, however, may have a significant effect on other variables that PTP depends upon. This study examined the effects of lengthening the vertical uniform glottal duct on the transglottal and intraglottal pressures, and the derived transglottal pressure coefficients, for five glottal diameters (0...
June 6, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28594301/orbital-abscess-following-posterior-subtenon-injection-of-triamcinolone-acetonide
#20
Maedbh Rhatigan, Lisa McAnena, Elizabeth McElnea, Paul Connell, Tim Fulcher
Orbital cellulitis is a serious sight threatening and potentially life threatening condition which can be complicated by orbital abscess formation. Posterior subtenon (PST) injection of corticosteroid is commonly used in the treatment of posterior segment inflammation including post-operative macular oedema. We report a case of orbital abscess formation as a late complication of PST triamcinolone acetonide and discuss the presentation, diagnosis and management.
June 2017: Orbit
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