Afef Abdelwahed, Ines Skandrani, Soumaya Kilani, A Neffati, Mohamed Ben Sghaier, Ines Bouhlel, Jihed Boubaker, Rebaï Ben Ammar, Amor Mahmoud, Kamel Ghedira, Leila Chekir-Ghedira
Mutagenic and antimutagenic activities against direct acting mutagens, nifuroxazide (NF) and sodium azide (SA), and indirect acting mutagen aflatoxin B1 (AFB1) of extracts prepared from aerial parts of Pituranthos tortuosus were investigated in bacterial assay systems (i.e., the Ames test with Salmonella typhimurium TA100, TA98, TA1538, TA1535, and the SOS chromotest with Escherichia coli PQ 37). It was found that all extracts obtained from P. tortuosus decreased the mutagenicity induced by AFB1 (10 microg/assay), SA (1...
2008: Drug and Chemical Toxicology