keyword
https://read.qxmd.com/read/38656150/stepwise-progression-of-dye-induced-in-situ-photoalignment-and-subsequent-stabilization-for-noncontact-alignment-of-liquid-crystals
#21
JOURNAL ARTICLE
Aboozar Nasrollahi, Avinash Kumar Rella, Vineet Kumar, Shin-Woong Kang
Noncontact alignment of liquid crystals (LCs) is crucial for large-area and ultrahigh definition (UHD) display manufacturing. This research presents an innovative approach to the photoalignment of LCs, aiming to overcome challenges associated with uniformity and assembly in large-sized and UHD displays. Using homogeneously dissolved, nonionic azobenzene chromophores sensitive to both visible and UV light, we demonstrate an in situ stepwise progression of dye-induced LC alignment and subsequent stabilization using reactive mesogen (RM)...
April 24, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38651798/covalent-functionalization-of-1d-and-2d-sp-2-carbon-nanoallotropes-twelve-years-of-progress-2011-2023
#22
REVIEW
Zunaira Amjad, Artur P Terzyk, Sławomir Boncel
Carbon nanoallotropes have attracted significant attention in the field of materials science due to their unique combination of physicochemical and biological properties, with numerous applications. One-dimensional (1D) and two-dimensional (2D) sp2 -carbon nanoallotropes, such as carbon nanohorns (CNHs), carbon nanotubes (CNTs), and graphene, have emerged as prominent candidates for a variety of technological advancements. To fully exploit their exceptional characteristics, the covalent functionalization of these nanostructures may alleviate the problems with the processing and final performance...
April 23, 2024: Nanoscale
https://read.qxmd.com/read/38650087/decreased-grip-strength-is-associated-with-paraspinal-muscular-oxidative-stress-in-female-lumbar-degenerative-disease-patients
#23
JOURNAL ARTICLE
Ryosuke Takahashi, Hidetoshi Nojiri, Yukoh Ohara, Toshiyuki Fujiwara, Muneaki Ishijima
We aimed to investigate the relationship between superoxide dismutase 2-related oxidative stress in the paraspinal muscles and spinal alignment, clinical skeletal muscle parameters, and mitochondrial function. Multifidus muscle samples from patients who underwent posterior lumbar surgery were analyzed. Patients with diseases affecting oxidative stress and spinal alignment were excluded. The superoxide dismutase 2 redox index was defined as the ratio of reactive oxygen species (superoxide) to antioxidant enzymes (superoxide dismutase 2) and was used as an index of oxidative stress...
April 22, 2024: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://read.qxmd.com/read/38644701/examination-of-quality-of-life-and-psychiatric-symptoms-in-childhood-graves-disease
#24
JOURNAL ARTICLE
Gözde Yazkan Akgül, Özge Köprülü
OBJECTIVES: The aim of our study is to examine the emotional, behavioral problems, and psychiatric symptoms of children diagnosed with Graves' disease (GD), to assess their quality of life, and to compare with control group. METHODS: The research was planned as a cross-sectional study and included 16 patients with GD (13 female and three male) and 29 healthy children for control group (19 female and 10 male). Sociodemographic form, Pediatric Quality of Life Inventory, Revised Child Anxiety and Depression Scale-Child Version (RCADS-CV), Strengths and Difficulties Questionnaire (SDQ), Turgay DSM-IV-Based Child and Adolescent Behavior Disorders Screening and Rating Scale (T-DSM-IV-S), and Affective Reactivity Index scale were applied to the children and their families...
April 22, 2024: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://read.qxmd.com/read/38644216/exploring-the-effectiveness-of-carboxymethylated-and-crosslinked-albizia-procera-gum-in-diltiazem-hydrochloride-matrix-tablets-a-comparative-analysis
#25
JOURNAL ARTICLE
Sudipta Mukherjee, Jasmina Khanam
This study investigates the efficacy of modified Albizia procera gum as a release-retardant polymer in Diltiazem hydrochloride (DIL) matrix tablets. Carboxymethylated Albizia procera gum (CAP) and ionically crosslinked carboxymethylated Albizia procera gum (Ca-CAP) were utilized, with Ca-CAP synthesized via crosslinking CAP with calcium ions (Ca2+ ) using calcium chloride (CaCl2 ). FTIR analysis affirmed polymer compatibility, while Differential scanning calorimetry (DSC) and X-ray diffraction (XRD) assessed thermal behavior and crystallinity, respectively...
April 19, 2024: Chemical & Pharmaceutical Bulletin
https://read.qxmd.com/read/38644163/association-of-endothelial-dysfunction-and-peripheral-arterial-disease-with-sarcopenia-in-chronic-kidney-disease
#26
JOURNAL ARTICLE
Bang-Gee Hsu, Chih-Hsien Wang, Yu-Hsien Lai, Chiu-Huang Kuo, Yu-Li Lin
BACKGROUND: Endothelial dysfunction and peripheral arterial disease (PAD), which disturb skeletal muscle microperfusion, are highly prevalent in patients with chronic kidney disease (CKD). We evaluated the association of endothelial dysfunction and PAD with sarcopenia in patients with non-dialysis CKD. METHODS: This cross-sectional study included 420 patients with stages 3-5 non-dialysis CKD aged 69.0 ± 11.8 years. Skeletal muscle index (skeletal muscle mass/height2 ), handgrip strength, 6-m gait speed and strength of hip flexion and knee extension were measured...
April 21, 2024: Journal of Cachexia, Sarcopenia and Muscle
https://read.qxmd.com/read/38642043/oxygen-impurity-tuned-structure-and-adhesion-properties-of-the-cu-sio-2-interface
#27
JOURNAL ARTICLE
Mengdie Lan, Gaosheng Yan, Wenshan Yu, Shengping Shen
The properties of the Cu/SiO2 interface usually deteriorate in the complex atmospheric environment, which may limit its performance and application in the engineering. Using the reactive molecular dynamics method, we investigate how the mechanical behaviors of the Cu/SiO2 interface change as it interacts with oxygen impurities. The interfacial oxidation degree could be enhanced as O2 penetrates into the interface area. This makes the interfacial structure disordered and is not conducive to the survival of Cu-O-Si bondings, which reduces the tensile and shear strengths of the interface...
April 20, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38637286/warm-reactive-autoantibodies-detected-by-solid-phase-technology-patient-characteristics-laboratory-features-and-clinical-significance
#28
JOURNAL ARTICLE
Douglas P Blackall, Jennifer T Little
OBJECTIVES: This study focused on the serology, clinical characteristics, and hemolytic potential of warm reactive autoantibodies detected by solid phase red cell adherence. METHODS: Ninety-seven patients with warm autoantibodies were evaluated. Serologic characteristics included the strength of solid phase reactivity, the results of tube-based ancillary testing, direct antiglobulin test and eluate results, and an assessment for contemporaneous alloantibodies. Clinical characteristics of the patients included age, sex, and primary diagnosis...
April 18, 2024: American Journal of Clinical Pathology
https://read.qxmd.com/read/38633745/swine-influenza-a-virus-challenges-and-novel-vaccine-strategies
#29
REVIEW
Erika Petro-Turnquist, Matthew J Pekarek, Eric A Weaver
Swine Influenza A Virus (IAV-S) imposes a significant impact on the pork industry and has been deemed a significant threat to global public health due to its zoonotic potential. The most effective method of preventing IAV-S is vaccination. While there are tremendous efforts to control and prevent IAV-S in vulnerable swine populations, there are considerable challenges in developing a broadly protective vaccine against IAV-S. These challenges include the consistent diversification of IAV-S, increasing the strength and breadth of adaptive immune responses elicited by vaccination, interfering maternal antibody responses, and the induction of vaccine-associated enhanced respiratory disease after vaccination...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38632641/effect-of-preoperative-immunonutrition-on-postoperative-short-term-clinical-outcomes-in-patients-with-gastric-cancer-cachexia-a-prospective-randomized-controlled-trial
#30
RANDOMIZED CONTROLLED TRIAL
Junjian Yu, Antai Yuan, Qi Liu, Wei Wang, Yuqi Sun, Zequn Li, Cheng Meng, Yanbing Zhou, Shougen Cao
BACKGROUND: Although current guidelines(ESPEN guideline: Clinical nutrition in surgery and other guidelines) recommend preoperative immunonutrition for cachectic gastric cancer patients, the strength of the recommendation is weak, and the level of evidence is low. The benefits of preoperative immunonutrition still remain controversial. PATIENTS AND METHODS: 112 patients with gastric cancer cachexia were enrolled in the study and randomly assigned in a 1:1 ratio to receive either preoperative enteral immunonutrition support (IN, n = 56) or standard enteral nutrition support (SEN, n = 56)...
April 17, 2024: World Journal of Surgical Oncology
https://read.qxmd.com/read/38629947/phase-state-regulates-photochemical-hono-production-from-nano-3-dicarboxylic-acid-mixtures
#31
JOURNAL ARTICLE
Qiong Li, Shuaishuai Ma, Yu Liu, Xinyuan Wu, Hongbo Fu, Xiang Tu, Shuwen Yan, Liwu Zhang, Christian George, Jianmin Chen
Field observations of daytime HONO source strengths have not been well explained by laboratory measurements and model predictions up until now. More efforts are urgently needed to fill the knowledge gaps concerning how environmental factors, especially relative humidity (RH), affect particulate nitrate photolysis. In this work, two critical attributes for atmospheric particles, i.e., phase state and bulk-phase acidity, both influenced by ambient RH, were focused to illuminate the key regulators for reactive nitrogen production from typical internally mixed systems, i...
April 17, 2024: Environmental Science & Technology
https://read.qxmd.com/read/38622097/age-dependent-changes-in-the-production-of-mitochondrial-reactive-oxygen-species-in-human-skeletal-muscle
#32
JOURNAL ARTICLE
Mikhail Yu Vyssokikh, Maksim A Vigovskiy, Vladislav V Philippov, Yakov R Boroday, Mariya V Marey, Olga A Grigorieva, Tatiana F Vepkhvadze, Nadezhda S Kurochkina, Ludmila A Manukhova, Anastasiya Yu Efimenko, Daniil V Popov, Vladimir P Skulachev
A decrease in muscle mass and its functionality (strength, endurance, and insulin sensitivity) is one of the integral signs of aging. One of the triggers of aging is an increase in the production of mitochondrial reactive oxygen species. Our study was the first to examine age-dependent changes in the production of mitochondrial reactive oxygen species related to a decrease in the proportion of mitochondria-associated hexokinase-2 in human skeletal muscle. For this purpose, a biopsy was taken from m. vastus lateralis in 10 young healthy volunteers and 70 patients (26-85 years old) with long-term primary arthrosis of the knee/hip joint...
February 2024: Biochemistry. Biokhimii︠a︡
https://read.qxmd.com/read/38617634/theoretical-investigation-of-the-green-synthesized-carbon-based-nanomaterial-potential-as-inhibitors-of-ace2-for-blocking-sars-cov-2-binding
#33
JOURNAL ARTICLE
Harsiwi Candra Sari, Haliza Hasnia Putri, Pinantun Wiguna Kusuma Paksi, Gabriel Hidayat, Silmi Rahma Amelia, Citra Deliana Dewi Sundari, Heni Rachmawati, Atthar Luqman Ivansyah, Fahdzi Muttaqien, Ferry Iskandar
Since the emergence of SARS-CoV-2 in 2020, the world has faced a global pandemic, emphasizing the urgent need for effective treatments to combat COVID-19. This study explores the use of green-synthesized carbon-based nanomaterials as potential inhibitors of ACE2, a critical receptor for SARS-CoV-2 entry into host cells. Specifically, the study examines four carbon-based nanomaterials, namely, CD1, CD2, CD3, and CD4 in amino, graphitic, pyridinic, and pyrrolic forms, respectively, synthesized from curcumin, to investigate their binding affinity with ACE2...
April 9, 2024: ACS Omega
https://read.qxmd.com/read/38615810/multimodal-phototherapy-agents-target-lipid-droplets-for-near-infrared-imaging-guided-type-i-photodynamic-photothermal-therapy
#34
JOURNAL ARTICLE
Xianjiao Tang, Liping Chen, Yuhan Wang, Pengwei Chen, Lin-Song Li, Xiaojing Yang, Mei-Xia Zhao
The construction and optimization of a single phototherapeutic agent with photoluminescence, type I photodynamic therapy (PDT), and photothermal therapy (PTT) functions remain challenging. In this study, we aimed to design and synthesize four donor-acceptor (D-A) type aggregation-induced emission molecules: PSI, TPSI, PSSI, and TPSSI. We employed phenothiazine as an electron donor and 1,3-bis(dicyanomethylidene)indan as a strong electron acceptor in the synthesis process. Among them, TPSSI exhibited efficient type I reactive oxygen species generation, high photothermal conversion efficiency (45...
April 12, 2024: Acta Biomaterialia
https://read.qxmd.com/read/38615625/metformin-improves-sarcopenia-related-quality-of-life-in-geriatric-adults-a-randomized-controlled-trial
#35
JOURNAL ARTICLE
Rizwan Qaisar, Asima Karim, Tahir Muhammad, M Shahid Iqbal, Firdos Ahmad
OBJECTIVES: Metformin protects against age-related muscle decline, termed sarcopenia. However, the effects on sarcopenia quality-of-life (SarQoL) are unknown. We investigated the effects of metformin on SarQoL and associated mechanisms in older adults. METHOD: This double-blind randomized, placebo-controlled trial included geriatric adult men, divided into non-sarcopenic controls (age = 72.2 ± 4.3 years, n = 52) and two groups of patients with sarcopenia randomized into placebo (age at baseline = 74...
April 13, 2024: Archives of Medical Research
https://read.qxmd.com/read/38615260/interface-reactive-sputtering-of-transparent-electrode-for-high-performance-monolithic-and-stacked-perovskite-tandem-solar-cells
#36
JOURNAL ARTICLE
Yiman Dong, Runnan Yu, Gangfeng Su, Zongwen Ma, Zhangwei He, Ruyue Wang, Yuling Zhang, Jing Yang, Yongshuai Gong, Minghua Li, Zhan'ao Tan
Sputtered indium tin oxide (ITO) fulfills the requirements of top transparent electrodes (TTEs) in semitransparent perovskite solar cells (PSCs) and stacked tandem solar cells (TSCs), as well as of the recombination layers in monolithic TSCs. However, the high-energy ITO particles will cause damage to the devices. Herein, the interface reactive sputtering strategy is proposed to construct cost-effective TTEs with high transmittance and excellent carrier transporting ability. Polyethylenimine (PEI) is chosen as the interface reactant that can react with sputtered ITO nanoparticles, so that, coordination compounds can be formed during the deposition process, facilitating the carrier transport at the interface of C60 /PEI/ITO...
April 14, 2024: Advanced Materials
https://read.qxmd.com/read/38611924/adsorption-of-o-2-on-the-preferred-o-au-sites-of-small-gold-oxide-clusters-charge-dependent-interaction-and-activation
#37
JOURNAL ARTICLE
Lulu Huang, Wen Liu, Xiaopeng Xing
Decades of research have illuminated the significant roles of gold/gold oxide clusters in small molecule catalytic oxidation. However, many fundamental questions, such as the actual sites to adsorb and activate O2 and the impact of charge, remain unanswered. Here, we have utilized an improved genetic algorithm program coupled with the DFT method to systematically search for the structures of Au1-5 O x -/+/0 ( x = 1-4) and calculated binding interactions between Au1-5 O x -/+/0 ( x = 1-2) and O2 , aiming to determine the active sites and to elucidate the impact of different charge states in gold oxide systems...
April 6, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38611235/improving-the-3d-printability-and-mechanical-performance-of-biorenewable-soybean-oil-based-photocurable-resins
#38
JOURNAL ARTICLE
Marius Bodor, Aurora Lasagabáster-Latorre, Goretti Arias-Ferreiro, María Sonia Dopico-García, María-José Abad
The general requirement of replacing petroleum-derived plastics with renewable resources is particularly challenging for new technologies such as the additive manufacturing of photocurable resins. In this work, the influence of mono- and bifunctional reactive diluents on the printability and performance of resins based on acrylated epoxidized soybean oil (AESO) was explored. Polyethylene glycol di(meth)acrylates of different molecular weights were selected as diluents based on the viscosity and mechanical properties of their binary mixtures with AESO...
April 3, 2024: Polymers
https://read.qxmd.com/read/38611130/synthesis-of-a-novel-p-n-triazine-containing-ring-flame-retardant-and-its-application-in-epoxy-resin
#39
JOURNAL ARTICLE
Yi Yu, Junlei Chen, Anxin Ding, Changzeng Wang, Yunfei Wang, Ling Yang
To meet the environmental protection and flame retardancy requirements for epoxy resins (EPs) in certain fields, in this study, a novel triazine-ring-containing DOPO-derived compound (VDPD), derived from vanillin, 2,4-Diamino-6-phenyl-1,3,5-triazine, and 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO), was synthesized using a one-pot method. Flame-retardant epoxy resin (FREP) was prepared by adding various ratios of VDPD to EP and curing with 4,4-diaminodiphenylmethane (DDM). The curing behavior, thermal stability, mechanical properties, and flame-retardant properties of the FREP were examined in various tests...
March 22, 2024: Polymers
https://read.qxmd.com/read/38609077/pearl-inspired-intelligent-marine-hetero-nanocomposite-coating-based-on-brick-mortar-strategy-anticorrosion-durability-and-switchable-antifouling
#40
JOURNAL ARTICLE
Jiahuan Liu, Zheming Tong, Feng Gao, Jun Wang, Jing Hu, Lina Song, Yang Hou, Jianguo Lu, Xiaoli Zhan, Qinghua Zhang
Corrosion activities and biofouling pose significant challenges for marine facilities, resulting in substantial economic losses. Inspired by the "brick&mortar" structure of pearls, a novel nanocomposite coating (Pun-HJTx ) with long-lasting anticorrosion and intelligent antifouling modes is fabricated by integrating a compatible MoS2 /MXene heterostructure as the "brick" into a polyurea-modified PDMS (Pun) acting as "mortar." Notably, the presence of multiple hydrogen bonds within the coating effectively reduces the pinholes resulted from solution volatilizing...
April 12, 2024: Advanced Materials
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