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https://www.readbyqxmd.com/read/28741974/sarcopenia-and-physical-function-are-associated-with-inflammation-and-arteriosclerosis-in-community-dwelling-people-the-yakumo-study
#1
Tetsuro Hida, Shiro Imagama, Kei Ando, Kazuyoshi Kobayashi, Akio Muramoto, Kenyu Ito, Yoshimoto Ishikawa, Mikito Tsushima, Yoshihiro Nishida, Naoki Ishiguro, Yukiharu Hasegawa
OBJECTIVES: Sarcopenia reduces physical function, while chronic inflammation causes arteriosclerosis and decreases skeletal muscle. We conducted a cross-sectional study to elucidate the associations among sarcopenia, physical function, arteriosclerosis, and inflammation in community-dwelling people. METHODS: We recruited 335 participants in an annual health checkup. We diagnosed sarcopenia based on appendicular skeletal muscle mass index (aSMI) assessed by bioelectrical impedance analysis...
July 25, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/28741938/new-synthesis-of-nzvi-c-composites-as-an-efficient-adsorbent-for-the-uptake-of-u-vi-from-aqueous-solutions
#2
Haibo Liu, Mengxue Li, Tianhu Chen, Changlun Chen, Njud S Alharbi, Tasawar Hayat, Dong Chen, Qiang Zhang, Yubing Sun
New nanoscale zero-valent iron/carbon (nZVI/C) composites were successfully synthesized by heating natural hematite and pine sawdust at 800 ºC under nitrogen conditions. The characteristic results indicated that as-prepared nZVI/C composites presented the massive reactive sites by SEM, XRD, FT-IR and XPS techniques. No effect of ionic strength revealed that inner-sphere surface complexation dominated uptake of U(VI) on nZVI/C composites. The uptake mechanism of U(VI) on nZVI/C composites was demonstrated to be the simultaneous adsorption and reduction by XPS and XANES techniques...
July 25, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28740866/distinct-properties-of-the-triplet-pair-state-from-singlet-fission
#3
M Tuan Trinh, Andrew Pinkard, Andrew B Pun, Samuel N Sanders, Elango Kumarasamy, Matthew Y Sfeir, Luis M Campos, Xavier Roy, X-Y Zhu
Singlet fission, the conversion of a singlet exciton (S1) to two triplets (2 × T1), may increase the solar energy conversion efficiency beyond the Shockley-Queisser limit. This process is believed to involve the correlated triplet pair state (1)(TT). Despite extensive research, the nature of the (1)(TT) state and its spectroscopic signature remain actively debated. We use an end-connected pentacene dimer (BP0) as a model system and show evidence for a tightly bound (1)(TT) state. It is characterized in the near-infrared (IR) region (~1...
July 2017: Science Advances
https://www.readbyqxmd.com/read/28733209/intervention-strength-does-not-differentially-affect-memory-reconsolidation-of-strong-memories
#4
Kevin van Schie, Suzanne C van Veen, Yanniek R Hendriks, Marcel A van den Hout, Iris M Engelhard
Recently, it has become clear that retrieval (i.e., reactivation) of consolidated memories may return these memories into a labile state before they are restored into long-term memory ('reconsolidation'). Using behavioral manipulations, reactivated memories can be disrupted via the mechanism of novel learning. In the present study, we investigated whether changing a strong memory during reconsolidation depends on the strength of novel learning. To test this, participants (N = 144) in six groups acquired a relatively strong memory on Day 1 by viewing and recalling a series of pictures three times...
July 18, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28723816/importance-of-physical-qualities-for-speed-and-change-of-direction-ability-in-elite-female-soccer-players
#5
Stacey Emmonds, G Nicholson, C Beggs, B Jones, A Bissas
The purpose of this study was to determine the importance of physical qualities for speed and change of direction (CoD) ability in female soccer players. Data were collected on 10 female soccer players who were part of a professional English Women's Super League team. Player assessments included anthropometric (stature and body mass), body composition (dual-energy X-ray absorptiometry), speed (10m, 30m sprint), CoD ability (505 agility), aerobic (Yo-Yo Intermittent Recovery Test), lower-body strength (bilateral knee extensions) and power (countermovement jump [CMJ], squat jump [SJ], 30cm drop jump [DJ]) measures...
July 17, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28722410/the-general-effect-of-van-der-waals-interactions-on-the-stability-of-alkoxy-intermediates-on-metal-surfaces
#6
Yun-Fei Xu, Wei Chen, Efthimios Kaxiras, Cynthia M Friend, Robert J Madix
The critical role of non-covalent van der Waals (vdW) interactions in determining the relative stability of alkoxy intermediates has been demonstrated for the Cu(110) surface using a combination of experiment and theory. The results may be significant for the selectivity control of copper-based reactions of alcohols. Previous examination of this effect on Au(110) was also extended to include higher molecular weight alcohols; on Cu(110) and Au(110) the hierarchy for the strength of binding of the alkoxys was found to be the same within experimental accuracy, with alkoxy species of greater chain length being more stable...
July 19, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28721740/clinical-features-and-subjective-physiological-responses-to-emotional-stimuli-in-the-presence-of-emotion-dysregulation-in-attention-deficit-hyperactivity-disorder
#7
Candan Taskiran, Serkan Karaismailoglu, Halime Tuna Cak Esen, Zeynep Tuzun, Aysen Erdem, Zeynep Dicle Balkanci, Anil Barak Dolgun, Sadriye Ebru Cengel Kultur
INTRODUCTION: Emotion dysregulation (ED) has long been recognized in clinical descriptions of attention-deficit hyperactivity disorder (ADHD), but a renewed interest in ED has advanced research on the overlap between the two entities. Autonomic reactivity (AR) is a neurobiological correlate of emotion regulation; however, the association between ADHD and AR remains unclear. Our aim was to explore the clinical differences, AR, and subjective emotional responses to visual emotional stimuli in ADHD children with and without ED...
July 19, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28714308/supersensitive-oxidation-responsive-biodegradable-peg-hydrogels-for-glucose-triggered-insulin-delivery
#8
Mei Zhang, Cheng-Cheng Song, Fu-Sheng Du, Zi-Chen Li
Reactive oxygen species (ROS)-responsive polymers and hydrogels represent an emerging family of intelligent materials owing to the key functions of ROS in physiological processes or pathological diseases. Nonetheless, the weaknesses such as low sensitivity, slow response, instability, and low mechanical strength are associated with the limited ROS-responsive polymeric or supramolecular hydrogels. In this study, a novel type of oxidation-responsive degradable hydrogels was fabricated by the redox-initiated radical polymerization of a 4-arm-poly(ethylene glycol) (PEG) acrylic macromonomer that possesses a H2O2-cleavable phenylboronic acid linker in each of the arms...
July 25, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28714290/in-vitro-and-in-vivo-characterization-of-biodegradable-reactive-isocyanate-terminated-three-armed-and-hyperbranched-block-copolymeric-tissue-adhesives
#9
Agnieszka I Bochyńska, Gerjon Hannink, Jan J Rongen, Dirk W Grijpma, Pieter Buma
Tissue adhesives are an attractive class of biomaterials, which can serve as a treatment for meniscus tears. In this study, physicochemical and adhesive properties of novel biodegradable three-armed- and hyperbranched block copolymeric adhesives are evaluated. Additionally, their degradation in vitro and in vivo, and the tissue reaction after subcutaneous injection in rats are assessed. The developed adhesives have sufficient adhesive strength to meniscus tissue after curing (66-88 kPa). Networks based on the three-armed adhesive have tensile properties that are in the same range as human meniscus...
July 17, 2017: Macromolecular Bioscience
https://www.readbyqxmd.com/read/28713027/an-on-matrix-digestion-procedure-for-ap-ms-experiments-dissects-the-interplay-between-complex-conserved-and-serotype-specific-reactivities-in-dengue-virus-human-plasma-interactome
#10
Yassel Ramos, Vivian Huerta, Dayron Martín, Sucel Palomares, Alexis Yero, Dianne Pupo, Sebastien Gallien, Alejandro M Martín, Yasset Pérez-Riverol, Mónica Sarría, Osmany Guirola, Glay Chinea, Bruno Domon, Luis Javier González
The interactions between the four Dengue virus (DENV) serotypes and plasma proteins are crucial in the initial steps of viral infection to humans. Affinity purification combined with quantitative mass spectrometry analysis, has become one of the most powerful tools for the investigation on novel protein-protein interactions. Using this approach, we report here that a significant number of bait-interacting proteins do not dissociate under standard elution conditions, i.e. acid pH and chaotropic agents, and that this problem can be circumvented by using the "on-matrix" digestion procedure described here...
July 13, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28712288/the-role-of-orbital-interactions-and-activation-strain-distortion-energies-on-reactivities-in-the-normal-and-inverse-electron-demand-cycloadditions-of-strained-and-unstrained-cycloalkenes
#11
Brian J Levandowski, Trevor A Hamlin, F Matthias Bickelhaupt, Kendall N Houk
The Diels-Alder reactivities of a series of cycloalkenes, from the highly strained cyclopropene to the unstrained cyclohexene, have been studied with density functional theory using the M06-2X functional. The normal electron-demand Diels-Alder reactions with cyclopentadiene and the inverse electron-demand Diels-Alder reactions with 3,6-bis(trifluoromethyl)tetrazine were analyzed using the distortion/interaction-activation strain model. Previous studies showed that activation strain computed from the distorted reactants in the transition structures are larger for unstrained than strained cycloalkenes, and that most of the activation energy differences are accounted for by this difference...
July 16, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28712113/nutritional-status-is-the-major-factor-affecting-grip-strength-of-african-hiv-patients-before-and-during-antiretroviral-treatment
#12
Suzanne Filteau, G PrayGod, S L Woodd, Henrik Friis, D C Heimburger, J R Koethe, P Kelly, L Kasonka, Andrea M Rehman
OBJECTIVES: Low grip strength is a marker of frailty and a risk factor for mortality among HIV patients and other populations. We investigated factors associated with grip strength in malnourished HIV patients at referral to ART, and at 12 weeks and 2-3 years after starting ART. METHODS: The study involved HIV-infected Zambian and Tanzanian participants recruited to the NUSTART trial when malnourished (body mass index <18.5 kg/m(2) ) and requiring ART. The relationship of grip strength to nutritional, infectious and demographic factors was assessed by multivariable linear regression at referral for ART (n=1742) and after 12 weeks (n=778) and 2-3 years of ART (n=273)...
July 16, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28712066/effect-of-ph-and-ionic-strength-on-the-binding-strength-of-anti-pf4-polyanion-antibodies
#13
Thi-Huong Nguyen, Andreas Greinacher
Antibodies against the chemokine platelet factor 4 (PF4) in complex with heparin cause the prothrombotic adverse drug reaction heparin-induced thrombocytopenia (HIT). The current dilemma for laboratory diagnosis of HIT is that only about 50% of these antibodies are pathogenic, but the widely available enzyme immunosorbent assays (EIA), used for diagnosis in the clinical laboratory cannot differentiate between non-pathogenic- and pathogenic (platelet activating) antibodies. It would be highly desirable to improve diagnosis for HIT...
July 15, 2017: European Biophysics Journal: EBJ
https://www.readbyqxmd.com/read/28710471/effect-of-over-consolidation-and-shear-rate-on-the-residual-strength-of-soils-of-silty-sand-in-the-three-gorges-reservoir
#14
Deying Li, Kunlong Yin, Thomas Glade, Chin Leo
Estimation of the residual strength of the soil on the landslide sliding surface is essential for analyzing reactivated landslides. This study investigated the influence of over-consolidation ratio (OCR) and shear rate on the residual strength of SM-type (silty sand) landslide soils in the Three Gorge Reservoir using ring shear tests under drained conditions. A series of ring shear tests were conducted to measure the drained residual strength under over-consolidation ratios of 1-12 and shear rates of 0.06-30...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28694337/targeted-memory-reactivation-during-sleep-adaptively-promotes-the-strengthening-or-weakening-of-overlapping-memories
#15
J P Oyarzún, J Morís, D Luque, R de Diego-Balaguer, L Fuentemilla
System memory consolidation is conceptualized as an active process whereby newly encoded memory representations are strengthened through selective memory reactivation during sleep. However, our learning experience is highly overlapping in content (i.e., shares common elements), and memories of these events are organized in an intricate network of overlapping associated events. It remains to be explored whether and how selective memory reactivation during sleep has an impact on these overlapping memories acquired during awake time...
July 10, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28692103/supercharging-spycatcher-toward-an-intrinsically-disordered-protein-with-stimuli-responsive-chemical-reactivity
#16
Yang Cao, Dong Liu, Wen-Bin Zhang
We report a supercharged, intrinsically disordered protein, SpyCatcher(-), possessing stimuli-responsive reactivity toward SpyTag with tunable yields ranging from 4% to 98% depending on pH, temperature, ionic strength, etc. The CD and NMR studies reveal that the reaction occurs through a folded intermediate formed probably via a different mechanism from that of SpyCatcher.
July 10, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28686035/nanoscale-chemical-processes-affecting-storage-capacities-and-seals-during-geologic-co2-sequestration
#17
Young-Shin Jun, Lijie Zhang, Yujia Min, Qingyun Li
Geologic CO2 sequestration (GCS) is a promising strategy to mitigate anthropogenic CO2 emission to the atmosphere. Suitable geologic storage sites should have a porous reservoir rock zone where injected CO2 can displace brine and be stored in pores, and an impermeable zone on top of reservoir rocks to hinder upward movement of buoyant CO2. The injection wells (steel casings encased in concrete) pass through these geologic zones and lead CO2 to the desired zones. In subsurface environments, CO2 is reactive as both a supercritical (sc) phase and aqueous (aq) species...
July 7, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28673856/a-luciferase-immunoprecipitation-system-lips-assay-for-profiling-human-norovirus-antibodies
#18
Christine M Tin, Lijuan Yuan, Rachel J Dexter, Gabriel I Parra, Tammy Bui, Kim Y Green, Stanislav V Sosnovtsev
A luciferase immunoprecipitation systems (LIPS) assay was developed to define the antigenic specificity and titer of antibodies directed against human norovirus (HuNoV). Recombinant proteins, expressed by plasmid constructs encoding Renilla luciferase (Ruc) fused to the full-length HuNoV major capsid protein (VP1) (Ruc-antigen), were generated for ten HuNoV strains. In addition, subdomain constructs Ruc-Shell (S) and Ruc-Protruding (P) were engineered for a representative GII.4 norovirus (strain GII.4/2006b)...
July 1, 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/28673689/higher-adherence-to-the-vegetable-rich-dietary-pattern-is-related-to%C3%A2-longer-telomere-length-in-women
#19
Yunhui Gong, Guo Tian, Hongmei Xue, Xiao Zhang, Yong Zhao, Guo Cheng
BACKGROUND & AIMS: Increasing evidence suggests a role of nutrition in aging process measured by telomere length (TL). However, data from Chinese are scarce. Moreover, the potential mechanism underlying diet and aging is not clear. Although inflammation has been hypothesized as one of the main factors, direct evidence is lacking. We examined whether dietary patterns were associated with TL in Chinese adults, with particular attention paid to body fat (excessive accumulation of body fat is a state of high-systematic oxidative stress and inflammation) and C-reactive protein (CRP, a marker of inflammation)...
May 11, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28665340/the-buffer-effect-of-therapy-dog-exposure-on-stress-reactivity-in-undergraduate-students
#20
Alexandra J Fiocco, Anastasia M Hunse
Stress is an insidious health risk that is commonly reported among university students. While research suggests that dog exposure may facilitate recovery from a stress response, little is known about the buffer effect of dog exposure on the stress response to a future stressor. This study examined whether interaction with a therapy dog could reduce the strength of the physiological stress response when exposed to a subsequent stressor. Sixty-one university students were randomly assigned to either a therapy dog (TD, n = 31) or a no-dog control (C, n = 30) group...
June 30, 2017: International Journal of Environmental Research and Public Health
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