Mark G Young, Timothy J Straub, Colin J Worby, Hayden C Metsky, Andreas Gnirke, Ryan A Bronson, Lucas R van Dijk, Christopher A Desjardins, Christian Matranga, James Qu, Karen Dodson, Henry L Schreiber, Abigail L Manson, Scott J Hultgren, Ashlee M Earl
Low-abundance members of microbial communities are difficult to study in their native habitat. This includes Escherichia coli , a minor, but common inhabitant of the gastrointestinal tract and opportunistic pathogen, including of the urinary tract, where it causes most infections. While our understanding of the interactions between uropathogenic Escherichia coli (UPEC) and the bladder is increasing, comparatively little is known about UPEC in its pre-infection reservoir, partly due to its low abundance there (<1% relative abundance)...
February 29, 2024: bioRxiv