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Procyanidin

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https://www.readbyqxmd.com/read/29786838/edible-gum-phenolic-lipid-incorporated-gluten-films-for-food-packaging
#1
Rui Liu, Xu Cong, Yingshi Song, Tao Wu, Min Zhang
The aim of this investigation was to improve the barrier and mechanical properties of gluten films and further explore their application in the packaging of seasonings. The effects of flaxseed gum (FG), oligomeric procyanidins (OPCs), and lauric acid (LA) on the water vapor permeability (WVP), mechanical properties, and peroxide value (POV) were determined. FG and OPCs improved the WVP properties of the gluten films, whereas LA significantly improved the oxygen-barrier properties. The FG/OPCs/LA/GP composite film was then optimized, and the morphological, microstructural, and thermal properties of the composite gluten film were investigated by scanning electron microscopy, atomic force microscopy, surface hydrophobicity analysis; Fourier transform infrared spectroscopy; thermal gravimetric analysis, respectively...
May 22, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29784316/structural-profile-of-soluble-and-bound-phenolic-compounds-in-teff-eragrostis-tef-reveals-abundance-of-distinctly-different-flavones-in-white-and-brown-varieties
#2
Shreeya Ravisankar, Kebede Abegaz, Joseph M Awika
Reliable data on polyphenol in teff, an increasingly important food crop, is currently lacking. This study investigated the structural and quantitative profile of soluble and bound polyphenols in white and brown teff grown in Ethiopia and USA using LC-tandem quadrupole mass spectrometry. Thirty-four phenolic compounds (32 newly identified in teff), mostly flavones and phenolic acid derivatives, were characterized. Unusually high levels of flavones were present in both white (1398-2049 μg/g), and brown (1720-1847 μg/g) teff soluble fractions...
October 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29774883/-properties-of-decellularized-rabbit-carotid-artery-with-two-different-cross-linked-technologies-a-comparative-study
#3
Lei Huang, Feng Kuang, Demiao Kong, Xinmin Zhou
To compare the properties between decellularized rabbit carotid artery with different cross-linked technologies.
 Methods: The decellularized rabbit carotid arteries were randomly divided into a photo-oxidation group and a procyanidins group. One group was cross-linked with photo-oxidation and the other group was cross-linked with procyanidins. The in vitro or in vivo properties of the two groups were evaluated by testing heat-shrinking temperature, max tensile strength and the max elongation or by testing tissue structure, inflammatory reaction and calcification degree...
April 28, 2018: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/29770693/vine-shoot-tannins-effect-of-post-pruning-storage-and-toasting-treatment
#4
Cristina Cebrían-Tarancon, Rosario Sanchez-Gomez, Sergio Gómez-Alonso, Isidro Hermosin-Gutierrez, Adela Mena-Morales, Esteban García-Romero, M Rosario Salinas, Amaya Zalacain
For first time vine-shoot tannin composition was carried out by means of HPLC-DAD-ESI-MS/MS. Two vine-shoot cultivars (Airén and Cencibel) with different post-pruning storage time and submitted to a toasting process, were assayed. There was no trace of gallotannins nor ellagitannins, but a high proanthocyanidins content and a mean degree of polymerization (mDP) close to 3 was characterized. The higher concentration of proanthocyanidins corresponded to Airén after 6 months post-pruning storage and at 3 months for Cencibel...
May 17, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29751901/subcritical-water-extraction-of-polyphenolic-compounds-from-sorghum-sorghum-bicolor-l-bran-and-their-biological-activities
#5
Xiaoping Luo, Jiemei Cui, Haihui Zhang, Yuqing Duan
Subcritical water extraction (SWE), an environment-friendly technique, was applied to extract polyphenolics from sorghum bran. Extraction temperatures (°C), time (min), and solid-liquid ratio (mL/g) were investigated and optimized by Box-Behnken design. The optimized conditions for SWE was 144.5 °C of temperature, 21 min of time, and 35 mL/g of solid-liquid ratio, with a polyphenolics yield of 47.253 ± 0.375 mg GAE/g dw, which was in good agree with the predicted value. Comparing with hot water extraction (HWE), SWE resulted in a higher yield of polyphenolics, higher radical scavenging activities, and more efficient antiproliferative activity...
October 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29751684/polyphenolic-composition-and-antioxidant-activity-of-aqueous-and-ethanolic-extracts-from-uncaria-tomentosa-bark-and-leaves
#6
Mirtha Navarro-Hoyos, Diego Alvarado-Corella, Ileana Moreira-Gonzalez, Elizabeth Arnaez-Serrano, Maria Monagas-Juan
Uncaria tomentosa constitutes an important source of secondary metabolites with diverse biological activities mainly attributed until recently to alkaloids and triterpenes. We have previously reported for the first-time the polyphenolic profile of extracts from U. tomentosa , using a multi-step process involving organic solvents, as well as their antioxidant capacity, antimicrobial activity on aerial bacteria, and cytotoxicity on cancer cell lines. These promising results prompted the present study using food grade solvents suitable for the elaboration of commercial extracts...
May 11, 2018: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/29751077/procyanidin-b2-protects-against-d-galactose-induced-mimetic-aging-in-mice-metabolites-and-microbiome-analysis
#7
Ying Xiao, Jialin Dong, Zhiting Yin, Qiguo Wu, Yiming Zhou, Xiaoli Zhou
To elucidate the possible mechanisms for the preventive effect of procyanidin B2 on aging, a combined analysis of metabolic profile and gut microbiome was carried out in the present study. The mimetic aged mice induced by d-galactose injection (500 mg/kg, sc daily), and the preventive group was fed with the diet plus 0.2% procyanidin B2. After 7 weeks of treatment, the spatial memory was assayed using the Morris water maze test. Procyanidin B2 significantly ameliorated the impaired memory and antioxidant abilities induced by d-galactose...
May 8, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29747456/intestinal-absorption-and-antioxidant-activity-of-grape-pomace-polyphenols
#8
Veronica Sanda Chedea, Laurentiu Mihai Palade, Daniela Eliza Marin, Rodica Stefania Pelmus, Mihaela Habeanu, Mircea Catalin Rotar, Mihail Alexandru Gras, Gina Cecilia Pistol, Ionelia Taranu
The absorption and antioxidant activity of polyphenols from grape pomace (GP) are important aspects of its valorization as a feed additive in the diet of weaned piglets. This study aimed to evaluate the presence of polyphenols from GP both in vitro in IPEC cells and in vivo in the duodenum and colon of piglets fed with diets containing or not 5% GP and also to compare and correlate the aspects of their in vitro and in vivo absorption. Total polyphenolic content (TPC) and antioxidant status (TAS, CAT, SOD and GPx enzyme activity, and lipid peroxidation-TBARS level) were assessed in duodenum and colon of piglets fed or not a diet with 5% GP...
May 9, 2018: Nutrients
https://www.readbyqxmd.com/read/29740325/extract-enriched-in-flavan-3-ols-and-mainly-procyanidin-dimers-improves-metabolic-alterations-in-a-mouse-model-of-obesity-related-disorders-partially-via-estrogen-receptor-alpha
#9
Daniela Leonetti, Raffaella Soleti, Nicolas Clere, Luisa Vergori, Caroline Jacques, Lucie Duluc, Catherine Dourguia, Maria C Martínez, Ramaroson Andriantsitohaina
Red wine polyphenol extracts improve cardiovascular and metabolic disorders linked to obesity. Their vascular protection is mediated by the activation of the alpha isoform of the estrogen receptor (ERα). In the present study, we explored the effects of a grape seed extract (GSE) enriched in the flavan-3-ols procyanidin dimers on obesity-related cardiovascular and metabolic disorders; with a particular interest in the role/contribution of ERα. Ovariectomized wild type or ERα knockout (KO) mice were fed with standard or western diet, supplemented or not with GSE, for 12 weeks...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29739985/apple-procyanidins-promote-mitochondrial-biogenesis-and-proteoglycan-biosynthesis-in-chondrocytes
#10
Isao Masuda, Masato Koike, Shohei Nakashima, Yu Mizutani, Yusuke Ozawa, Kenji Watanabe, Yoko Sawada, Hiroshi Sugiyama, Atsushi Sugimoto, Hidetoshi Nojiri, Koichi Sashihara, Koutaro Yokote, Takahiko Shimizu
Apples are well known to have various benefits for the human body. Procyanidins are a class of polyphenols found in apples that have demonstrated effects on the circulatory system and skeletal organs. Osteoarthritis (OA) is a locomotive syndrome that is histologically characterized by cartilage degeneration associated with the impairment of proteoglycan homeostasis in chondrocytes. However, no useful therapy for cartilage degeneration has been developed to date. In the present study, we detected beneficial effects of apple polyphenols or their procyanidins on cartilage homeostasis...
May 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29739589/phenolic-and-triterpenoid-composition-and-inhibition-of-%C3%AE-amylase-of-pistachio-kernels-pistacia-vera-l-as-affected-by-rootstock-and-irrigation-treatment
#11
Luis Noguera-Artiaga, David Pérez-López, Armando Burgos-Hernández, Aneta Wojdyło, Ángel A Carbonell-Barrachina
The current water scarcity forces farmers to adopt new irrigation strategies to save water without jeopardizing the fruit yield and quality. In this study, the influence of 3 regulated deficit irrigation (RDI) treatments and 3 rootstocks on the functional quality of pistachios were studied. The functional parameters studied included, polyphenols, triterpenoids, and inhibition of α-amylase. The results showed that P. terebinthus and P. atlantica rootstocks led to pistachio kernels with higher contents of polyphenols and triterpenoids (mainly betulinic acid with 111 and 102 µg g-1 , respectively) than pistachios obtained using P...
September 30, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29737742/-procyanidins-enhance-the-chemotherapeutic-sensitivity-of-laryngeal-carcinoma-cells-to-cisplatin-through-autophagy-pathway
#12
Feng Yu, Wei Liu, Xiao Rong Gong, Yi Bo Zhou, Ying Lin
OBJECTIVES: To investigate the effect of Procyanidins (OPCs) on the autophagy of laryngeal cancer cell line TU686 and to explore the effect of OPCs on the chemosensitivity of laryngeal cancer cells to DDP in terms of autophagy and apoptosis. METHODS: CCK-8 was used to detected the effect of different concentrations of OPC and DDP on TU686 cell viability. Experimental grouping: Both kinds of cells were divided into CON group, DDP group, OPC group and MIX group. Annexin-V-FITC/PI double staining of flow cytometry was used to detect the effect of each experimental group on the apoptosis...
March 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29716863/analysis-of-the-main-constituents-of-changshu-tablet-and-its-spasmolysis-effect-against-contraction-induced-by-acetylcholine-in-the-rat-isolated-intestinal-smooth-muscle
#13
Ying An, Guangming Song, Dailin Liu, Tianyi Mao, Yanmin Zhao, Wenli Xie
The Changshu tablet (CST), one kind of Chinese patent medicine with astringent to the intestine and relieving diarrhea, was made by the root of Rose odorata Sweet var. gigantean (Coll.et Hemsl.) Rehd.et Wils. Although CST has a long history of clinical application, but the research of its chemical composition is less. So the objective of this study was to investigate the main constituents and preliminarily research its effect of the contraction of isolated intestine in vitro. The contents of total polyphenols (126...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29714395/cocoa-procyanidins-modulate-transcriptional-pathways-linked-to-inflammation-and-metabolism-in-human-dendritic-cells
#14
Helene L E Midttun, Aina Ramsay, Irene Mueller-Harvey, Andrew R Williams
Foods rich in polyphenols such as procyanidins (PC) have been proposed to have anti-inflammatory properties, and we have previously reported inhibition of lipopolysaccharide (LPS)-induced inflammatory cytokine secretion in human dendritic cells (DCs) by PC derived from cocoa. To explore the mechanistic basis of this inhibition, here we conducted transcriptomic analysis on DCs cultured with either LPS or LPS combined with oligomeric cocoa PC. Procyanidins suppressed a number of genes encoding cytokines and chemokines such as CXCL1, but also genes involved in the cGMP pathway such as GUCY1A3 (encoding guanylate cyclase soluble subunit alpha-3)...
May 1, 2018: Food & Function
https://www.readbyqxmd.com/read/29701782/grape-seed-procyanidin-extract-inhibits-adipogenesis-and-stimulates-lipolysis-of-porcine-adipocytes-in-vitro
#15
S Wei, Y Zheng, M Zhang, H Zheng, P Yan
The objective of this paper was to evaluate in vitro effect of grape seed procyanidin extract (GSPE) on differentiation, proliferation, and lipolysis of porcine adipocytes, providing a molecular basis for the use of GSPE in pig fat regulation. Primary preadipocytes isolated from subcutaneous adipose tissue of pigs were used as the in vitro cell model. Treatment of GSPE repressed preadipocyte differentiation, as evidenced by reduced lipid accumulation, decreased mRNA expressions of peroxisome proliferator-activated receptor gamma (PPARγ) and fatty acid binding protein 4 (FABP4) , as well as enhanced expressions of preadipocyte factor-1 (Pref-1)...
April 26, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29699679/impact-of-oligomeric-procyanidins-on-wheat-gluten-microstructure-and-physicochemical-properties
#16
Rui Liu, Chunyue Shi, Yingshi Song, Tao Wu, Min Zhang
We found that oligomeric procyanidins improve the physicochemical properties of wheat flour, and that a more compact and denser gluten microstructure is formed when an increasing amount of oligomeric procyanidins is incorporated. Further, we found that oligomeric procyanidins alter the rheological properties, molecular weight distribution, secondary structure, and thermal stability of gluten, and that oligomeric procyanidins alleviate the loss of extensibility and viscosity after the dough is exposed to high temperatures...
September 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29699669/antityrosinase-and-antioxidant-properties-of-mung-bean-seed-proanthocyanidins-novel-insights-into-the-inhibitory-mechanism
#17
Wei-Ming Chai, Chong Ou-Yang, Qian Huang, Mei-Zhen Lin, Ying-Xia Wang, Kai-Li Xu, Wen-Yang Huang, Dan-Dan Pang
This study investigated the structure, antioxidant activity, antityrosinase activity and mechanism of proanthocyanidins from mung bean seed [Vigna radiata (L.) Wilczek]. The structural composition were characterized by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), electrospray ionization-full-mass spectrometry (ESI-Full-MS), and high-pressure liquid chromatography-electrospray ionization-mass spectrometry (HPLC-ESI-MS) techniques. The mung bean seed proanthocyanidins were composed of procyanidins, prodelphinidins, and their rhamnosides...
September 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29680045/characterization-of-new-flavan-3-ol-derivatives-in-fermented-cocoa-beans
#18
Noémie Fayeulle, Anna Vallverdu-Queralt, Emmanuelle Meudec, Clotilde Hue, Renaud Boulanger, Véronique Cheynier, Nicolas Sommerer
Two series of compounds showing mass signals at m/z 605 and 893 (negative ionization mode) have been detected in fermented cocoa beans. This study objective is to identify these mass signals and characterize their structure in fermented cocoa samples. Our hypothesis is that these signals may correspond to ethyl-bridged flavan-3-ols resulting from flavan-3-ol condensation with acetaldehyde which is a microbial metabolite. Mass spectrometry was used to compare the retention times and mass fragmentation patterns between a model solution using epicatechin and procyanidin dimer B2, the major flavan-3-ols of cocoa, as precursors and extracts of fermented cocoa...
September 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29663390/static-kinetic-and-isotherm-adsorption-performances-of-macroporous-adsorbent-resins-for-recovery-and-enrichment-of-bioactive-procyanidins-from-cranberry-pomace
#19
Chi Gao, Shaomin Zhao, Yavuz Yagiz, Liwei Gu
This study examined the ability of five Amberlite resins coupled with ultrasound-assisted water extraction for the recovery and enrichment of bioactive procyanidins and total phenolics from cranberry pomace. Static adsorption showed that XAD-7HP had the highest adsorption capacity for procyanidins (52.2 mg/g resin) and total phenolics (99.1 mg/g resin) whereas XAD-761 had the lowest. Adsorption of procyanidins fitted better to pseudo-second-order kinetics than pseudo-first-order kinetics. Isotherm adsorption on XAD-7HP suggested that Langmuir isotherm was a better model to describe the adsorption of procyanidins while Kemkin-Pyzhev equation was better for total phenolics based on higher coefficient of determinations (R2 )...
April 16, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29659037/optimization-of-drying-process-and-pressurized-liquid-extraction-for-recovery-of-bioactive-compounds-from-avocado-peel-by-product
#20
Jorge G Figueroa, Isabel Borrás-Linare, Jesús Lozano-Sánchez, Rosa Quirantes-Piné, Antonio Segura-Carretero
The aim of the present study was to optimize the extraction of phenolic compounds in avocado peel using pressurized liquid extraction (PLE) with GRAS solvents. Response surface methodology (RSM) based on Central Composite Design 22 model was used in order to optimize PLE conditions. Moreover, the effect of air drying temperature on the total polyphenol content (TPC) and individual phenolic compounds concentration were evaluated. The quantification of individual compounds was performed by HPLC-DAD-ESI-TOF-MS...
April 16, 2018: Electrophoresis
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