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https://www.readbyqxmd.com/read/28665330/effects-of-epigallocatechin-3-gallate-on-autophagic-lipolysis-in-adipocytes
#1
Sang-Nam Kim, Hyun-Jung Kwon, Seun Akindehin, Hyun Woo Jeong, Yun-Hee Lee
Previous studies demonstrated effects of green tea on weight loss; however, green tea-induced modulation of adipocyte function is not fully understood. Here, we investigated effects of the major green tea phytochemical, epigallocatechin-3-gallate (EGCG) on triglyceride contents, lipolysis, mitochondrial function, and autophagy, in adipocytes differentiated from C₃H10T1/2 cells and immortalized pre-adipocytes in vitro. EGCG reduced the triglycerol content significantly in adipocytes by 25%, comparable to the nutrient starvation state...
June 30, 2017: Nutrients
https://www.readbyqxmd.com/read/28595182/the-effect-of-dietary-supplements-containing-green-tea-capsaicin-and-ginger-extracts-on-weight-loss-and-metabolic-profiles-in-overweight-women-a-randomized-double-blind-placebo-controlled-clinical-trial
#2
Mohsen Taghizadeh, Narjes Farzin, Sara Taheri, Mahnaz Mahlouji, Hossein Akbari, Fatemeh Karamali, Zatollah Asemi
BACKGROUND: This study was conducted to determine the effects of dietary supplements containing green tea, capsaicin and ginger extracts on weight loss and metabolic profiles among overweight women. METHODS: This randomized double-blind placebo-controlled clinical trial was implemented among 50 overweight women. Participants were randomly divided into 2 groups. Group A received dietary supplements containing 125 mg green tea, 25 mg capsaicin and 50 mg ginger extracts (n = 25) group B received placebos (n = 25) twice with lunch and twice with dinner daily for 8 weeks...
2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28584836/effect-of-green-tea-on-metabolic-and-hormonal-aspect-of-polycystic-ovarian-syndrome-in-overweight-and-obese-women-suffering-from-polycystic-ovarian-syndrome-a-clinical-trial
#3
Hatav Gasemi Tehrani, Maryam Allahdadian, Farzane Zarre, Hanie Ranjbar, Fateme Allahdadian
BACKGROUND AND OBJECTIVE: Polycystic ovarian syndrome (PCOS) is the common cause of Oligo-ovulation. This syndrome causes long-term metabolic issues as well as increase the risk of diabetes type 2, hypertension, dyslipidemia, and cardiovascular disease. The current research aimed to study the effect of green tea on weight and hormonal changes of women suffering from PCOS. METHODS: This two group, double-blind, randomized clinical trial was conducted in Isfahan city...
2017: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/28510251/short-term-effects-of-green-tea-chronotherapy-on-the-metabolic-homeostasis-of-mice-on-different-diets
#4
R P Amorim, I P Daher, F P D Arcangelo, M F Bellini, W A Orcini, G R Sarria, R L Peruquetti
Biological rhythms can be defined as changes in physiological or behavioral variables that repeat at certain time intervals. Rhythms that last approximately 24 h are referred to as circadian rhythms. Modern lifestyles have drastically affected human habits, as well as the population's eating habits. These changes have generated an epidemic of metabolic syndromes, such as obesity and diabetes. In an attempt to combat obesity, populations have attempted to use many different herbal remedies and plant-based drugs, the most common of which is Camellia sinensis, or green tea...
May 10, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28372210/a-rapid-atr-ftir-spectroscopic-method-for-detection-of-sibutramine-adulteration-in-tea-and-coffee-based-on-hierarchical-cluster-and-principal-component-analyses
#5
Nur Cebi, Mustafa Tahsin Yilmaz, Osman Sagdic
Sibutramine may be illicitly included in herbal slimming foods and supplements marketed as "100% natural" to enhance weight loss. Considering public health and legal regulations, there is an urgent need for effective, rapid and reliable techniques to detect sibutramine in dietetic herbal foods, teas and dietary supplements. This research comprehensively explored, for the first time, detection of sibutramine in green tea, green coffee and mixed herbal tea using ATR-FTIR spectroscopic technique combined with chemometrics...
August 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28038897/herbal-supplements-association-with-reversible-cerebral-vasoconstriction-syndrome-a-case-report
#6
REVIEW
Isabel Costa, Marcelo D Mendonça, Vera Cruz E Silva, Sofia Calado, Miguel Viana-Baptista
BACKGROUND: Reversible cerebral vasoconstriction syndrome (RCVS) is a clinico-radiologic syndrome characterized by thunderclap headache and reversible multifocal arterial constrictions that resolves within 3 months. RCVS can be either spontaneous or related to a trigger; vasoactive drugs including over-the-counter medicine are common culprits. Nevertheless, there are sparse data on the association of herbal supplements in the genesis of unexplained RCVS. METHODS: We describe a case of RCVS with a temporal association with the consumption of a diet pill composed of green tea, L-carnitine, and conjugated linoleic acid...
March 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27465483/usage-of-plant-food-supplements-pfs-for-weight-control-in-six-european-countries-results-from-the-plantlibra-pfs-consumer-survey-2011-2012
#7
Alicia Garcia-Alvarez, Raimon Mila-Villarroel, Lourdes Ribas-Barba, Bernadette Egan, Mihaela Badea, Franco M Maggi, Maija Salmenhaara, Patrizia Restani, Lluis Serra-Majem
BACKGROUND: Obesity is increasing worldwide and weight-control strategies, including the consumption of plant food supplements (PFS), are proliferating. This article identifies the herbal ingredients in PFS consumed for weight control and by overweight/obese dieters in six European countries, and explores the relationship between their consumption and their self-reported BMI. METHODS: Data used were a subset from the PlantLIBRA PFS Consumer Survey 2011-2012, a retrospective survey of 2359 PFS consumers...
July 28, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27450231/effects-of-greenselect-phytosome%C3%A2-on-weight-maintenance-after-weight-loss-in-obese-women-a-randomized-placebo-controlled-study
#8
RANDOMIZED CONTROLLED TRIAL
Luisa Gilardini, Lucia Pasqualinotto, Francesco Di Pierro, Paolo Risso, Cecilia Invitti
BACKGROUND: Most subjects regain weight after weight loss due to compensatory adaptations finalized to maintain stable body energy stores. Green tea (GT) preparations, which help maintain energy expenditure while dieting could be a useful strategy to facilitate weight maintenance. The usefulness of GT preparations in weight maintenance has been poorly studied so far with conflicting results. This study evaluated if a supplement of GSP and piperine helps obese women to maintain the weight loss obtained with a 3-month lifestyle intervention...
July 22, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27400086/the-antioxidant-effect-of-green-tea-mega-egcg-against-electromagnetic-radiation-induced-oxidative-stress-in-the-hippocampus-and-striatum-of-rats
#9
Nawal A Ahmed, Nasr M Radwan, Heba S Aboul Ezz, Noha A Salama
Electromagnetic radiation (EMR) of cellular phones may affect biological systems by increasing free radicals and changing the antioxidant defense systems of tissues, eventually leading to oxidative stress. Green tea has recently attracted significant attention due to its health benefits in a variety of disorders, ranging from cancer to weight loss. Thus, the aim of the present study was to investigate the effect of EMR (frequency 900 MHz modulated at 217 Hz, power density 0.02 mW/cm(2), SAR 1.245 W/kg) on different oxidative stress parameters in the hippocampus and striatum of adult rats...
2017: Electromagnetic Biology and Medicine
https://www.readbyqxmd.com/read/27189593/risk-of-liver-injury-associated-with-green-tea-extract-in-slimquick-%C3%A2-weight-loss-products-results-from-the-dilin-prospective-study
#10
Elizabeth X Zheng, Simona Rossi, Robert J Fontana, Raj Vuppalanchi, Jay H Hoofnagle, Ikhlas Khan, Victor J Navarro
INTRODUCTION: Herbal and dietary supplements (HDS) have been increasingly recognized as a cause for acute liver injury (Navarro et al. Hepatology 60(4):1399-1408, 2014; Bailey et al. J Nutr 141:261-266, 2011). HDS products frequently contain numerous ingredients, and are marketed under various product names. A perusal of marketed weight loss products indicates that green tea extract (GTE) is a common ingredient in many. We aimed to describe the course and outcome of six patients who developed liver injury attributed to SLIMQUICK(®) weight loss products...
August 2016: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/27009797/microneedle-mediated-intradermal-delivery-of-epigallocatechin-3-gallate
#11
A Puri, H X Nguyen, A K Banga
OBJECTIVE: Epigallocatechin-3-gallate (EGCG) is the physiologically most active and abundant flavanol, accounting for 50-80% of green tea catechins. It is an anti-inflammatory, antioxidant, chemopreventive and skin photoprotective agent. However, light sensitivity and low permeability of EGCG across the stratum corneum due to its high molecular weight as well as strong binding to the lipid bilayers in the skin make it difficult to be used as a key ingredient in cosmetic products. This study aimed to formulate a photostable hydrogel of EGCG with good rheological properties for dermal application and investigate the effect of skin microporation using maltose microneedles on its permeation through dermatomed porcine skin...
October 2016: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/26957301/l-theanine-a-component-of-green-tea-prevents-3-nitropropionic-acid-3-np-induced-striatal-toxicity-by-modulating-nitric-oxide-pathway
#12
Sumit Jamwal, Puneet Kumar
L-theanine is unique amino acid which readily crosses blood brain barrier and possesses neuroprotective potential against neurodegenerative disorders including Huntington disease (HD). HD is characterized by selective loss of GABAergic medium spiny neurons. 3-nitropropionic acid (3-NP) induces a spectrum of HD-like neuropathology in rat striatum and widely used as experimental tool to study HD. Therefore, the present study was intended to investigate the effect of L-theanine against 3-NP-induced striatal toxicity and to explore its possible mechanism...
March 9, 2016: Molecular Neurobiology
https://www.readbyqxmd.com/read/26836279/nutraceuticals-for-body-weight-management-the-role-of-green-tea-catechins
#13
REVIEW
Pilou L H R Janssens, Rick Hursel, Margriet S Westerterp-Plantenga
Green tea catechins mixed with caffeine have been proposed as adjuvants for maintaining or enhancing energy expenditure and for increasing fat oxidation, in the context of prevention and treatment of obesity. These catechins-caffeine mixtures seem to counteract the decrease in metabolic rate that occurs during weight loss. Their effects are of particular importance during weight maintenance after weight loss. Other metabolic targets may be fat absorption and the gut microbiota composition, but these effects still need further investigation in combination with weight loss...
August 1, 2016: Physiology & Behavior
https://www.readbyqxmd.com/read/26426126/melatonin-attenuates-epigallocatehin-3-gallate-triggered-hepatotoxicity-without-compromising-its-downregulation-of-hepatic-gluconeogenic-and-lipogenic-genes-in-mice
#14
Dongxu Wang, Yaqing Wei, Taotao Wang, Xiaochun Wan, Chung S Yang, Russel J Reiter, Jinsong Zhang
(-)-Epigallocatehin-3-gallate (EGCG), a major constituent of green tea, can ameliorate metabolic syndrome at least in part through reducing gluconeogenesis and lipogenesis. Green tea extracts, of which EGCG is a key constituent, have been used for weight loss in humans. A potential adverse effect of high-dose EGCG or green tea extracts is hepatotoxicity. Melatonin, an endogenous antioxidant with a high safety profile, is effective in preventing various types of tissue damage. The current study investigated the influence of melatonin on EGCG-triggered hepatotoxicity and EGCG-downregulated hepatic genes responsible for gluconeogenesis and lipogenesis in mice...
November 2015: Journal of Pineal Research
https://www.readbyqxmd.com/read/26269377/obesity-phytotherapy-review-of-native-herbs-used-in-traditional-medicine-for-obesity
#15
REVIEW
Mahmoud Bahmani, Zohreh Eftekhari, Kourosh Saki, Ezatollah Fazeli-Moghadam, Mahyar Jelodari, Mahmoud Rafieian-Kopaei
Obesity is an important disorders due to which 25 million deaths occur annually worldwide. Synthetic drugs for weight loss have low efficacy and high side effects. Apart from synthetic drugs in modern medicine, various other methods including the use of herbal medications are used to induce weight loss. Cambodia hoodia, green tea, Citrus aurantium, white beans, fenugreek, caffeine, ephedrine, capsaicin, yohimbine, chitosan, fitostreols, and guar gum have been studied in clinical trials and their effects have been confirmed...
July 2016: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/26205229/consuming-a-multi-ingredient-thermogenic-supplement-for-28-days-is-apparently-safe-in-healthy-adults
#16
Roxanne M Vogel, Jordan M Joy, Paul H Falcone, Matt M Mosman, Michael P Kim, Jordan R Moon
BACKGROUND: Thermogenic (TRM) supplements are often used by people seeking to decrease body weight. Many TRM supplements are formulated with multiple ingredients purported to increase energy expenditure and maximize fat loss. However, in the past some TRM ingredients have been deemed unsafe and removed from the market. Therefore, it is important to verify the safety of multi-ingredient TRM supplements with chronic consumption. OBJECTIVE: To assess the safety of daily consumption of a multi-ingredient TRM supplement over a 28-day period in healthy adults...
2015: Food & Nutrition Research
https://www.readbyqxmd.com/read/26199579/purple-tea-and-its-extract-suppress-diet-induced-fat-accumulation-in-mice-and-human-subjects-by-inhibiting-fat-absorption-and-enhancing-hepatic-carnitine-palmitoyltransferase-expression
#17
Hiroshi Shimoda, Shoketsu Hitoe, Seikou Nakamura, Hisashi Matsuda
A number of clinical trials have been completed using green tea and black tea to investigate their effect in controlling weight in overweight adults. The results of these investigations, however, have often been contradictory, with some trials reporting positive effects of tea supplementation and some trials reporting no effect. As a result, the use of these teas for weight loss is controversial. Purple tea is a variety of green tea developed in Kenya (called TRFK306), which in addition to certain tea constituents found in green tea, also contains anthocyanins...
June 2015: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/26093535/therapeutic-effect-of-high-dose-green-tea-extract-on-weight-reduction-a-randomized-double-blind-placebo-controlled-clinical-trial
#18
I-Ju Chen, Chia-Yu Liu, Jung-Peng Chiu, Chung-Hua Hsu
BACKGROUND AND AIMS: To examine the effect and safety of high-dose green tea extract (Epigallocatechin gallate, EGCG) at a daily dosage of 856.8 mg on weight reduction and changes of lipid profile and obesity-related hormone peptides in women with central obesity. METHODS: We conducted a randomized, double-blind trial registered under ClinicalTrials.gov Identifier no. NCT02147041. A total of 115 women with central obesity were screened at our clinic. 102 of them with a body mass index (BMI) ≥ 27 kg/m(2) and a waist circumference (WC) ≥ 80 cm were eligible for the study...
June 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/26091183/a-minireview-of-effects-of-green-tea-on-energy-expenditure
#19
REVIEW
Duygu Türközü, Nilüfer Acar Tek
In recent years, individuals have begun to tend more frequently to some natural and herbal products to be used alone or as a combination with diet and exercise for ensuring the weight loss. Green tea is the leading one of these products. In some studies, it is reported that the green tea causes an increase in thermogenesis and substrate with fat oxidation by affecting on the sympathetic nervous system. It is reported that green tea has two main components that are associated with energy expenditure. One of them is caffeine and the other is catechin content...
January 22, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/25975988/hepatotoxicity-of-green-tea-an-update
#20
REVIEW
Gabriela Mazzanti, Antonella Di Sotto, Annabella Vitalone
Green tea (GT), obtained from the leaves of Camellia sinensis (L.) Kuntze (Fam. Theaceae), is largely used for its potential health benefits such as reduction in risk of cardiovascular diseases and weight loss. Nevertheless, it is suspected to induce liver damage. Present work reviews the hepatic adverse reactions associated with GT-based herbal supplements, published by the end of 2008 to March 2015. A systematic research was carried out on PubMed, MedlinePlus, Scopus and Google Scholar databases, without any language restriction...
August 2015: Archives of Toxicology
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