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https://www.readbyqxmd.com/read/28070314/calories-and-sugars-in-boba-milk-tea-implications-for-obesity-risk-in-asian-pacific-islanders
#1
Jae Eun Min, David B Green, Loan Kim
In the last several decades, obesity rates have reached epidemic proportions, and increases the risk for a host of comorbidities, including diabetes, cardiovascular disease, and certain kinds of cancers. Boba milk tea, first became popular in the 1990s throughout Asia, and has gained more popularity in the United States and in Europe since 2000. Currently, available nutrition data from online sites suggest this beverage contains high amounts of sugar and fat. One published nutrition study suggests that boba tea drinks are part of the larger group of sugar-sweetened beverages (SSB) because these beverages are usually sweetened with high-fructose corn syrup (HFCS)...
January 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28040599/green-tea-epigallocatechin-3-gallate-alleviates-hyperglycemia-and-reduces-advanced-glycation-end-products-via-nrf2-pathway-in-mice-with-high-fat-diet-induced-obesity
#2
Chethan Sampath, Muhammed Raihan Rashid, Shengmin Sang, Mohamed Ahmedna
Epigallocatechin 3-gallate (EGCG) from green tea may reduce plasma glucose and alleviate complications of diabetes by attenuating advanced glycation end products (AGEs) formation. We hypothesized that EGCG would mitigate AGEs formation via activating the nuclear factor erythroid-2-related-factor-2 (Nrf2) pathway in a mouse model of high fat diet-induced obesity. Dietary EGCG was tested in C57BL/6 mice that were placed on a high-fat diet with or without ECGC for 17 weeks and compared to a control group placed on low-fat diet for the same period...
December 29, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27976976/antiadipogenic-effects-and-mechanisms-of-combinations-of-genistein-epigallocatechin-3-gallate-and-or-resveratrol-in-preadipocytes
#3
Bulbul Ahmed, Siqin Liu, Hongwei Si
Natural bioactive compounds are considered an excellent alternative strategy for developing effective, safe, and cost-effective antiobesity agents. The aim of this study was to investigate if combinations of soy bean genistein (G), green tea epigallocatechin-3-gallate (E), and/or grape resveratrol (R) at low dosages synergistically inhibit preadipocyte differentiation both in 3T3-L1 cells and human primary preadipocytes (HPAs). Our results show that combinations of G, E, and/or R additively inhibited preadipocyte differentiation (39-56% of control) both in 3T3-L1 cells at 30 μM and HPAs at 15 μM, while the individual compounds have no antiadipogenic effect at the selected concentrations...
December 15, 2016: Journal of Medicinal Food
https://www.readbyqxmd.com/read/27941615/mechanisms-of-body-weight-reduction-by-black-tea-polyphenols
#4
REVIEW
Haibo Pan, Ying Gao, Youying Tu
Obesity is one of the most common nutritional diseases worldwide. This disease causes health problems, such as dyslipidemia, hyperglycemia, hypertension and inflammation. There are drugs used to inhibit obesity. However, they have serious side effects outweighing their beneficial effects. Black tea, commonly referred to as "fermented tea", has shown a positive effect on reducing body weight in animal models. Black tea polyphenols are the major components in black tea which reduce body weight. Black tea polyphenols are more effective than green tea polyphenols...
December 7, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27940057/epigallocatechin-3-gallate-inhibits-adipogenesis-through-down-regulation-of-ppar%C3%AE-and-fas-expression-mediated-by-pi3k-akt-signaling-in-3t3-l1-cells
#5
Mengqing Wu, Dan Liu, Rong Zeng, Tao Xian, Yi Lu, Guohua Zeng, Zhangzetian Sun, Bowei Huang, Qiren Huang
Epigallocatechin-3-gallate (EGCG), a major component in green tea, functions as extensive bioactivities including anti-inflammation, anti-oxidation, and anti-cancer. However, little is known about its anti-adipogenesis and underlying mechanisms. The purport of this study sought to investigate effects of EGCG on 3T3-L1 preadipocyte differentiation and to explore its possible mechanisms. The 3T3-L1 cells were induced to differentiate under the condition of pro-adipogenic cocktail with or without indicated EGCG concentrations (10, 50, 100, 200µM) for 2, 4, 6 and 8 days, respectively...
December 7, 2016: European Journal of Pharmacology
https://www.readbyqxmd.com/read/27921383/consumption-of-the-total-western-diet-differentially-affects-the-response-to-green-tea-in-rodent-models-of-chronic-disease-compared-to-the-ain93g-diet
#6
Robert E Ward, Abby D Benninghoff, Brett J Healy, Minghao Li, Bharath Vagu, Korry J Hintze
SCOPE: In pre-clinical studies investigating bioactive components, the efficacy of the bioactive is likely influenced by the basal diet provided to rodents. In this study, we hypothesized that a model bioactive, green tea extract (GTE), would have different effects on colon carcinogenesis, body composition, and lipid metabolism in mice fed a basal diet formulated to promote animal health and growth (AIN93G) as compared to a Western diet that emulates typical American intakes of micro- and macronutrients, the total Western diet (TWD)...
December 6, 2016: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/27845787/the-effect-of-green-tea-polyphenols-on-gut-microbial-diversity-and-fat-deposition-in-c57bl-6j-hfa-mice
#7
Li Wang, Benhua Zeng, Xiaojing Zhang, Zhenlin Liao, Lihui Gu, Zhiwei Liu, Qingping Zhong, Hong Wei, Xiang Fang
Quantitative and qualitative changes in gut microbial composition have been linked to obesity and obesity-related complications, and eating pattern has been shown to significantly impact the gut microbiome. Meanwhile, tea polyphenols are known to have health benefits such as improving glucose tolerance and decreasing liver fat deposition that may be helpful in combating obesity and obesity-related disorders. We therefore studied the effect of green tea polyphenols on gut microbial diversity and fat deposition in C57BL/6J Human Flora-Associated (HFA) mice, which were divided into five groups: low fat (LF), high fat (HF), high fat + 0...
December 7, 2016: Food & Function
https://www.readbyqxmd.com/read/27812583/the-modulatory-effect-of-infusions-of-green-tea-oolong-tea-and-black-tea-on-gut-microbiota-in-high-fat-induced-obese-mice
#8
Zhibin Liu, Zhichao Chen, Hongwen Guo, Dongping He, Huiru Zhao, Zhiyao Wang, Wen Zhang, Lan Liao, Chen Zhang, Li Ni
Tea consumption has been identified to have an anti-obesity effect. Whether it is associated with gut microbiota modulation is investigated in this study. Phenolic profiles of infusions of green tea, oolong tea and black tea were comprehensively compared first, by utilizing ultra-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry (UPLC-ESI-Q-TOFMS). Subsequently, high-fat-diet induced obese C57BL/6J mice were orally administered these three types of tea infusions for 13 weeks to evaluate their anti-obesity and gut microbiota modulatory effects...
December 7, 2016: Food & Function
https://www.readbyqxmd.com/read/27806972/effects-of-green-tea-catechin-extract-on-serum-lipids-in-postmenopausal-women-a-randomized-placebo-controlled-clinical-trial
#9
Hamed Samavat, April R Newman, Renwei Wang, Jian-Min Yuan, Anna H Wu, Mindy S Kurzer
BACKGROUND: Green tea has been suggested to improve cardiovascular disease risk factors, including circulating lipid variables. However, current evidence is predominantly based on small, short-term randomized controlled trials conducted in diverse populations. OBJECTIVE: The aim of this study was to examine the efficacy and impact of green tea extract (GTE) supplementation high in epigallocatechin gallate (EGCG) on blood lipids in healthy postmenopausal women. DESIGN: This was an ancillary study of a double-blind, randomized, placebo-controlled, parallel-arm trial investigating the effects of a GTE supplement containing 1315 mg catechins (843 mg EGCG) on biomarkers of breast cancer risk...
December 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27797683/short-term-effects-of-green-tea-on-blood-pressure-endothelial-function-and-metabolic-profile-in-obese-prehypertensive-women-a-crossover-randomized-clinical-trial
#10
Lívia de P Nogueira, José Firmino Nogueira Neto, Márcia R S T Klein, Antonio F Sanjuliani
BACKGROUND: Green tea consumption has been inversely associated with cardiovascular disease (CVD) in epidemiological studies. Although some interventional trials suggest that green tea has beneficial effects on CVD risk factors, such as hypertension and obesity, others have failed to show such benefits. AIMS: To evaluate the short-term effects of green tea on blood pressure, endothelial function, metabolic profile, and inflammatory activity in obese prehypertensive women...
October 31, 2016: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/27754422/effect-of-green-tea-extract-on-systemic-metabolic-homeostasis-in-diet-induced-obese-mice-determined-via-rna-seq-transcriptome-profiles
#11
Ji-Young Choi, Ye Jin Kim, Ri Ryu, Su-Jung Cho, Eun-Young Kwon, Myung-Sook Choi
Green tea (GT) has various health effects, including anti-obesity properties. However, the multiple molecular mechanisms of the effects have not been fully determined. The aim of this study was to elucidate the anti-obesity effects of GT via the analysis of its metabolic and transcriptional responses based on RNA-seq profiles. C57BL/6J mice were fed a normal, high-fat (60% energy as fat), or high-fat + 0.25% (w/w) GT diet for 12 weeks. The GT extract ameliorated obesity, hepatic steatosis, dyslipidemia, and insulin resistance in diet-induced obesity (DIO) mice...
October 14, 2016: Nutrients
https://www.readbyqxmd.com/read/27725410/the-combination-of-green-tea-extract-and-eriodictyol-inhibited-high-fat-high-sucrose-diet-induced-cholesterol-upregulation-is-accompanied-by-suppression-of-cholesterol-synthesis-enzymes
#12
Mai Yamashita, Motofumi Kumazoe, Yuki Nakamura, Yeong Seon Won, Jaehoon Bae, Shuya Yamashita, Hirofumi Tachibana
Western diets induce obesity associated with an increased risk of hypercholesterolaemia. Indeed, obesity-induced hypercholesterolaemia is correlated with increased coronary cardiovascular disease (CVD) risk. Male C57BL/6J mice were fed a normal diet, high-fat and high-sucrose diet (HF/HS), HF/HS with green tea extract powder diet (HF/HS+GT), HF/HS with eriodictyol diet (HF/HS+Eri), or HF/HS with green tea extract powder and eriodictyol diet (HF/HS+GT+Eri) for 8 wk. Body weight was lower in the HF/HS+GT+Eri group than in the HF/HS group (-8...
2016: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/27722362/molecular-mechanisms-of-the-anti-obesity-effect-of-bioactive-compounds-in-tea-and-coffee
#13
REVIEW
Min-Hsiung Pan, Yen-Chen Tung, Guliang Yang, Shiming Li, Chi-Tang Ho
Obesity is a serious health problem in adults and children worldwide. However, the basic strategies for the management of obesity (diet, exercise, drugs and surgery) have limitations and side effects. Therefore, many researchers have sought to identify bioactive components in food. Tea and coffee are the most frequently consumed beverages in the whole world. Their health benefits have been studied for decades, especially those of green tea. The anti-obesity effect of tea and coffee has been studied for at least ten years...
November 9, 2016: Food & Function
https://www.readbyqxmd.com/read/27698343/green-tea-reduces-body-fat-via-upregulation-of-neprilysin
#14
M Muenzner, N Tappenbeck, F Gembardt, R Rülke, J Furkert, M F Melzig, W-E Siems, G A Brockmann, T Walther
BACKGROUND/OBJECTIVE: Consumption of green tea has become increasingly popular, particularly because of claimed reduction in body weight. We recently reported that animals with pharmacological inhibition (by candoxatril) or genetic absence of the endopeptidase neprilysin (NEP) develop an obese phenotype. We now investigated the effect of green tea extract (in drinking water) on body weight and body composition and the mediating role of NEP. SUBJECTS/METHODS: To elucidate the role of NEP in mediating the beneficial effects of green tea extract, 'Berlin fat mice' or NEP-deficient mice and their age- and gender-matched wild-type controls received the extract in two different doses (300 or 600 mg kg(-1) body weight per day) in the drinking water...
December 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27689985/beneficial-effects-of-tea-and-the-green-tea-catechin-epigallocatechin-3-gallate-on-obesity
#15
REVIEW
Takuji Suzuki, Monira Pervin, Shingo Goto, Mamoru Isemura, Yoriyuki Nakamura
Green tea has been shown to have beneficial effects against cancer, obesity, atherosclerosis, diabetes, bacterial and viral infections, and dental caries. The catechin (-)-epigallocatechin-3-gallate (EGCG) has shown the highest biological activity among green tea catechins (GTCs) in most of the studies. While several epidemiological studies have shown the beneficial effects of tea and GTCs on obesity, some studies have failed to do this. In addition, a large number of interventional clinical studies have shown these favorable effects, and cellular and animal experiments have supported those findings, and revealed the underlying anti-obesity mechanisms...
September 29, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27634207/anti-inflammatory-action-of-green-tea
#16
Tomokazu Ohishi, Shingo Goto, Pervin Monira, Mamoru Isemura, Yoriyuki Nakamura
BACKGROUND: Green tea has been shown to have beneficial effects against a variety of diseases such as cancer, obesity, diabetes, cardiovascular disease, and neurodegenerative diseases. Through cellular, animal, and human experiments, green tea and its major component, epigallocatechin-3-gallate (EGCG) have been demonstrated to have anti-inflammatory effects. Our previous findings have indicated that green tea and EGCG suppress the gene and/or protein expression of inflammatory cytokines and inflammation-related enzymes...
September 15, 2016: Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/27600055/green-tea-extract-and-catechol-o-methyltransferase-genotype-modify-the-post-prandial-serum-insulin-response-in-a-randomised-trial-of-overweight-and-obese-post-menopausal-women
#17
A M Dostal, A Arikawa, L Espejo, S Bedell, M S Kurzer, N R Stendell-Hollis
BACKGROUND: Green tea extract (GTE) may be involved in a favourable post-prandial response to high-carbohydrate meals. The catechol-O-methyltransferase (COMT) genotype may modify these effects. We examined the acute effects of GTE supplementation on the post-prandial response to a high-carbohydrate meal by assessing appetite-associated hormones and glucose homeostasis marker concentrations in women who consumed 843 mg of (-)-epigallocatechin-3-gallate (EGCG) or placebo capsules for 11-12 months...
September 7, 2016: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/27528497/immobilized-tannase-treatment-alters-polyphenolic-composition-in-teas-and-their-potential-anti-obesity-and-hypoglycemic-activities-in-vitro
#18
Bruna Sampaio Roberto, Gabriela Alves Macedo, Juliana Alves Macedo, Isabela Mateus Martins, Vânia Mayumi Nakajima, J William Allwood, Derek Stewart, Gordon J McDougall
The aim of this work was to assess the effect of immobilized-tannase treatment on black, green, white and mate tea components and on their bioactivities relevant to obesity. Tannase treatment caused predictable changes in polyphenol composition with substantial reduction in galloylated catechins in green, white and black tea. Mate tea, which is rich in chlorogenic acids, was much less affected by tannase treatment although some degradation of caffeoyl quinic acid derivatives was noted. The original tea samples were effective in inhibiting digestive enzymes in vitro...
September 14, 2016: Food & Function
https://www.readbyqxmd.com/read/27489005/consumption-of-walnuts-in-combination-with-other-whole-foods-produces-physiologic-metabolic-and-gene-expression-changes-in-obese-c57bl-6j-high-fat-fed-male-mice
#19
Ting Luo, Omar Miranda-Garcia, Allysa Adamson, Jill Hamilton-Reeves, Debra K Sullivan, Jason M Kinchen, Neil F Shay
BACKGROUND: Although a reductionist approach has sought to understand the roles of individual nutrients and biochemicals in foods, it has become apparent that there can be differences when studying food components in isolation or within the natural matrix of a whole food. OBJECTIVE: The objective of this study was to determine the ability of whole-food intake to modulate the development of obesity and other metabolic dysfunction in mice fed a high-fat (HF), Western-style obesogenic diet...
September 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/27468160/green-tea-epigallocatechin-3-gallate-counteracts-daytime-overeating-induced-by-high-fat-diet-in-mice
#20
Hongyu Li, Huiling Calvina Kek, Joy Lim, Richard Wayne Gelling, Weiping Han
SCOPE: High-fat diet (HFD) induces overeating and obesity. Green tea (-)-epigallocatechin-3-gallate (EGCG) reduces HFD-induced body weight and body fat gain mainly through increased lipid metabolism and fat oxidation. However, little is known about its effect on HFD-induced alterations in feeding behavior. METHODS AND RESULTS: Three diet groups of wildtype C57B/6j male mice at 5 months old were fed on normal chow diet, 1 week of HFD (60% of energy) and 3 months of HFD (diet-induced obesity (DIO)) prior to EGCG supplement in respective diet...
December 2016: Molecular Nutrition & Food Research
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