keyword
MENU ▼
Read by QxMD icon Read
search

green tea obesity obese

keyword
https://www.readbyqxmd.com/read/28510251/short-term-effects-of-green-tea-chronotherapy-on-the-metabolic-homeostasis-of-mice-on-different-diets
#1
R P Amorim, I P Daher, F P D Arcangelo, M F Bellini, W A Orcini, G R Sarria, R L Peruquetti
Biological rhythms can be defined as changes in physiological or behavioral variables that repeat at certain time intervals. Rhythms that last approximately 24 h are referred to as circadian rhythms. Modern lifestyles have drastically affected human habits, as well as the population's eating habits. These changes have generated an epidemic of metabolic syndromes, such as obesity and diabetes. In an attempt to combat obesity, populations have attempted to use many different herbal remedies and plant-based drugs, the most common of which is Camellia sinensis, or green tea...
May 10, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28507012/dietary-factors-promoting-brown-and-beige-fat-development-and-thermogenesis
#2
REVIEW
Meshail Okla, Jiyoung Kim, Karsten Koehler, Soonkyu Chung
Brown adipose tissue (BAT) is a specialized fat tissue that has a high capacity to dissociate cellular respiration from ATP utilization, resulting in the release of stored energy as heat. Adult humans possess a substantial amount of BAT in the form of constitutively active brown fat or inducible beige fat. BAT activity in humans is inversely correlated with adiposity, blood glucose concentrations, and insulin sensitivity; this suggests that strategies aimed at BAT-mediated bioenergetics are an attractive therapeutic target in combating the continuing epidemic of obesity and diabetes...
May 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/28445390/prevention-of-colorectal-cancer-by-targeting-obesity-related-disorders-and-inflammation
#3
REVIEW
Yohei Shirakami, Masaya Ohnishi, Hiroyasu Sakai, Takuji Tanaka, Masahito Shimizu
Colorectal cancer is a major healthcare concern worldwide. Many experimental and clinical studies have been conducted to date to discover agents that help in the prevention of this disease. Chronic inflammation in colonic mucosa and obesity, and its related metabolic abnormalities, are considered to increase the risk of colorectal cancer. Therefore, treatments targeting these factors might be a promising strategy to prevent the development of colorectal cancer. Among a number of functional foods, various phytochemicals, including tea catechins, which have anti-inflammatory and anti-obesity properties, and medicinal agents that ameliorate metabolic disorders, might also be beneficial in the prevention of colorectal cancer...
April 26, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28381812/a-simple-enzymatic-biotransformation-method-using-fresh-green-tea-leaves-efficiently-generates-theaflavin-containing-fermentation-water-that-has-potent-physiological-functions-in-mice-and-humans
#4
Masumi Takemoto, Hiroaki Takemoto, Haruka Kouno, Tomomi Soeda, Takamichi Moriya
The polyphenolic compound theaflavin, the main red pigment in black tea, possesses many beneficial properties, such as fat-reducing and glucose-lowering capabilities. To produce theaflavin-containing fermentation water on a large scale, we have developed a simple, inexpensive, and selective enzymatic biotransformation method to obtain sufficient levels from fresh green tea leaves. Subsequent administration of theaflavin-containing fermentation water to obese mice on a high-fat diet inhibited body weight gain, decreased casual blood glucose and fasting blood glucose levels, and lowered mesenteric and total fat composition...
April 1, 2017: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28352352/combination-therapy-with-catechins-and-caffeine-inhibits-fat-accumulation-in-3t3-l1-cells
#5
Xiaojuan Zhu, Licong Yang, Feng Xu, Lezhen Lin, Guodong Zheng
Catechins and caffeine, which are green tea components, have a slimming effect; however, the combinational effect of fat metabolism in 3T3-L1 cells remains unclear. In the present study, 3T3-L1 cells were treated with catechins and caffeine in combination, and it was found that combination therapy with catechins and caffeine markedly reduced intracellular fat accumulation, mRNA expression levels of peroxisome proliferator-activated receptor-γ and CCAAT/enhancer-binding protein α in the early stage of cell differentiation were significantly reduced, and mRNA expression of fatty acid synthetase(FAS) andglycerol-3-phosphate dehydrogenase protein expression levels of FAS were downregulated...
February 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28154178/green-tea-polyphenol-epigallocatechin-3-gallate-suppresses-toll-like-receptor-4-expression-via-up-regulation-of-e3-ubiquitin-protein-ligase-rnf216
#6
Motofumi Kumazoe, Yuki Nakamura, Mai Yamashita, Takashi Suzuki, Kanako Takamatsu, Yuhui Huang, Jaehoon Bae, Shuya Yamashita, Motoki Murata, Shuhei Yamada, Yuki Shinoda, Wataru Yamaguchi, Yui Toyoda, Hirofumi Tachibana
Toll-like receptor 4 (TLR4) plays an essential role in innate immunity through inflammatory cytokine induction. Recent studies demonstrated that the abnormal activation of TLR4 has a pivotal role in obesity-induced inflammation, which is associated with several diseases, including hyperinsulinemia, hypertriglyceridemia, and cardiovascular disease. Here we demonstrate that (-)-epigallocatechin-3-O-gallate, a natural agonist of the 67-kDa laminin receptor (67LR), suppressed TLR4 expression through E3 ubiquitin-protein ring finger protein 216 (RNF216) up-regulation...
March 10, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28137482/epigallocatechin-3-gallate-egcg-activates-ampk-through-the-inhibition-of-glutamate-dehydrogenase-in-muscle-and-pancreatic-%C3%A3-cells-a-potential-beneficial-effect-in-the-pre-diabetic-state
#7
Shirin Pournourmohammadi, Mariagrazia Grimaldi, Malin H Stridh, Vanessa Lavallard, Helle S Waagepetersen, Claes B Wollheim, Pierre Maechler
Glucose homeostasis is determined by insulin secretion from the ß-cells in pancreatic islets and by glucose uptake in skeletal muscle and other insulin target tissues. While glutamate dehydrogenase (GDH) senses mitochondrial energy supply and regulates insulin secretion, its role in the muscle has not been elucidated. Here we investigated the possible interplay between GDH and the cytosolic energy sensing enzyme 5'-AMP kinase (AMPK), in both isolated islets and myotubes from mice and humans. The green tea polyphenol epigallocatechin-3-gallate (EGCG) was used to inhibit GDH...
January 27, 2017: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/28132656/fermented-green-tea-extract-exhibits-hypolipidaemic-effects-through-the-inhibition-of-pancreatic-lipase-and-promotion-of-energy-expenditure
#8
Dae-Bang Seo, Hyun Woo Jeong, Yeon-Ji Kim, Sukyung Kim, Jeongkee Kim, Ji Hae Lee, Kyungmi Joo, Jin Kyu Choi, Song Seok Shin, Sung-Joon Lee
Hyperlipidaemia is a major cause of atherosclerosis and related CVD and can be prevented with natural substances. Previously, we reported that a novel Bacillus-fermented green tea (FGT) exerts anti-obesity and hypolipidaemic effects. This study further investigated the hypotriglyceridaemic and anti-obesogenic effects of FGT and its underlying mechanisms. FGT effectively inhibited pancreatic lipase activity in vitro (IC50, 0·48 mg/ml) and ameliorated postprandial lipaemia in rats (26 % reduction with 500 mg/kg FGT)...
January 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28070314/calories-and-sugars-in-boba-milk-tea-implications-for-obesity-risk-in-asian-pacific-islanders
#9
Jae Eun Min, David B Green, Loan Kim
In the last several decades, obesity rates have reached epidemic proportions, and increases the risk for a host of comorbidities, including diabetes, cardiovascular disease, and certain kinds of cancers. Boba milk tea, first became popular in the 1990s throughout Asia, and has gained more popularity in the United States and in Europe since 2000. Currently, available nutrition data from online sites suggest this beverage contains high amounts of sugar and fat. One published nutrition study suggests that boba tea drinks are part of the larger group of sugar-sweetened beverages (SSB) because these beverages are usually sweetened with high-fructose corn syrup (HFCS)...
January 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28040599/green-tea-epigallocatechin-3-gallate-alleviates-hyperglycemia-and-reduces-advanced-glycation-end-products-via-nrf2-pathway-in-mice-with-high-fat-diet-induced-obesity
#10
Chethan Sampath, Muhammed Raihan Rashid, Shengmin Sang, Mohamed Ahmedna
Epigallocatechin 3-gallate (EGCG) from green tea may reduce plasma glucose and alleviate complications of diabetes by attenuating advanced glycation end products (AGEs) formation. We hypothesized that EGCG would mitigate AGEs formation via activating the nuclear factor erythroid-2-related-factor-2 (Nrf2) pathway in a mouse model of high fat diet-induced obesity. Dietary EGCG was tested in C57BL/6 mice that were placed on a high-fat diet with or without ECGC for 17 weeks and compared to a control group placed on low-fat diet for the same period...
March 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27976976/antiadipogenic-effects-and-mechanisms-of-combinations-of-genistein-epigallocatechin-3-gallate-and-or-resveratrol-in-preadipocytes
#11
Bulbul Ahmed, Siqin Liu, Hongwei Si
Natural bioactive compounds are considered an excellent alternative strategy for developing effective, safe, and cost-effective antiobesity agents. The aim of this study was to investigate if combinations of soy bean genistein (G), green tea epigallocatechin-3-gallate (E), and/or grape resveratrol (R) at low dosages synergistically inhibit preadipocyte differentiation both in 3T3-L1 cells and human primary preadipocytes (HPAs). Our results show that combinations of G, E, and/or R additively inhibited preadipocyte differentiation (39-56% of control) both in 3T3-L1 cells at 30 μM and HPAs at 15 μM, while the individual compounds have no antiadipogenic effect at the selected concentrations...
February 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/27941615/mechanisms-of-body-weight-reduction-by-black-tea-polyphenols
#12
REVIEW
Haibo Pan, Ying Gao, Youying Tu
Obesity is one of the most common nutritional diseases worldwide. This disease causes health problems, such as dyslipidemia, hyperglycemia, hypertension and inflammation. There are drugs used to inhibit obesity. However, they have serious side effects outweighing their beneficial effects. Black tea, commonly referred to as "fermented tea", has shown a positive effect on reducing body weight in animal models. Black tea polyphenols are the major components in black tea which reduce body weight. Black tea polyphenols are more effective than green tea polyphenols...
December 7, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27940057/epigallocatechin-3-gallate-inhibits-adipogenesis-through-down-regulation-of-ppar%C3%AE-and-fas-expression-mediated-by-pi3k-akt-signaling-in-3t3-l1-cells
#13
Mengqing Wu, Dan Liu, Rong Zeng, Tao Xian, Yi Lu, Guohua Zeng, Zhangzetian Sun, Bowei Huang, Qiren Huang
Epigallocatechin-3-gallate (EGCG), a major component in green tea, functions as extensive bioactivities including anti-inflammation, anti-oxidation, and anti-cancer. However, little is known about its anti-adipogenesis and underlying mechanisms. The purport of this study sought to investigate effects of EGCG on 3T3-L1 preadipocyte differentiation and to explore its possible mechanisms. The 3T3-L1 cells were induced to differentiate under the condition of pro-adipogenic cocktail with or without indicated EGCG concentrations (10, 50, 100, 200µM) for 2, 4, 6 and 8 days, respectively...
January 15, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/27921383/consumption-of-the-total-western-diet-differentially-affects-the-response-to-green-tea-in-rodent-models-of-chronic-disease-compared-to-the-ain93g-diet
#14
Robert E Ward, Abby D Benninghoff, Brett J Healy, Minghao Li, Bharath Vagu, Korry J Hintze
SCOPE: In pre-clinical studies investigating bioactive components, the efficacy of the bioactive is likely influenced by the basal diet provided to rodents. In this study, we hypothesized that a model bioactive, green tea extract (GTE), would have different effects on colon carcinogenesis, body composition, and lipid metabolism in mice fed a basal diet formulated to promote animal health and growth (AIN93G) as compared to a Western diet that emulates typical American intakes of micro- and macronutrients, the total Western diet (TWD)...
December 6, 2016: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/27845787/the-effect-of-green-tea-polyphenols-on-gut-microbial-diversity-and-fat-deposition-in-c57bl-6j-hfa-mice
#15
Li Wang, Benhua Zeng, Xiaojing Zhang, Zhenlin Liao, Lihui Gu, Zhiwei Liu, Qingping Zhong, Hong Wei, Xiang Fang
Quantitative and qualitative changes in gut microbial composition have been linked to obesity and obesity-related complications, and eating pattern has been shown to significantly impact the gut microbiome. Meanwhile, tea polyphenols are known to have health benefits such as improving glucose tolerance and decreasing liver fat deposition that may be helpful in combating obesity and obesity-related disorders. We therefore studied the effect of green tea polyphenols on gut microbial diversity and fat deposition in C57BL/6J Human Flora-Associated (HFA) mice, which were divided into five groups: low fat (LF), high fat (HF), high fat + 0...
December 7, 2016: Food & Function
https://www.readbyqxmd.com/read/27812583/the-modulatory-effect-of-infusions-of-green-tea-oolong-tea-and-black-tea-on-gut-microbiota-in-high-fat-induced-obese-mice
#16
Zhibin Liu, Zhichao Chen, Hongwen Guo, Dongping He, Huiru Zhao, Zhiyao Wang, Wen Zhang, Lan Liao, Chen Zhang, Li Ni
Tea consumption has been identified to have an anti-obesity effect. Whether it is associated with gut microbiota modulation is investigated in this study. Phenolic profiles of infusions of green tea, oolong tea and black tea were comprehensively compared first, by utilizing ultra-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry (UPLC-ESI-Q-TOFMS). Subsequently, high-fat-diet induced obese C57BL/6J mice were orally administered these three types of tea infusions for 13 weeks to evaluate their anti-obesity and gut microbiota modulatory effects...
December 7, 2016: Food & Function
https://www.readbyqxmd.com/read/27806972/effects-of-green-tea-catechin-extract-on-serum-lipids-in-postmenopausal-women-a-randomized-placebo-controlled-clinical-trial
#17
Hamed Samavat, April R Newman, Renwei Wang, Jian-Min Yuan, Anna H Wu, Mindy S Kurzer
BACKGROUND: Green tea has been suggested to improve cardiovascular disease risk factors, including circulating lipid variables. However, current evidence is predominantly based on small, short-term randomized controlled trials conducted in diverse populations. OBJECTIVE: The aim of this study was to examine the efficacy and impact of green tea extract (GTE) supplementation high in epigallocatechin gallate (EGCG) on blood lipids in healthy postmenopausal women. DESIGN: This was an ancillary study of a double-blind, randomized, placebo-controlled, parallel-arm trial investigating the effects of a GTE supplement containing 1315 mg catechins (843 mg EGCG) on biomarkers of breast cancer risk...
December 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27797683/short-term-effects-of-green-tea-on-blood-pressure-endothelial-function-and-metabolic-profile-in-obese-prehypertensive-women-a-crossover-randomized-clinical-trial
#18
Lívia de P Nogueira, José Firmino Nogueira Neto, Márcia R S T Klein, Antonio F Sanjuliani
BACKGROUND: Green tea consumption has been inversely associated with cardiovascular disease (CVD) in epidemiological studies. Although some interventional trials suggest that green tea has beneficial effects on CVD risk factors, such as hypertension and obesity, others have failed to show such benefits. AIMS: To evaluate the short-term effects of green tea on blood pressure, endothelial function, metabolic profile, and inflammatory activity in obese prehypertensive women...
February 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/27754422/effect-of-green-tea-extract-on-systemic-metabolic-homeostasis-in-diet-induced-obese-mice-determined-via-rna-seq-transcriptome-profiles
#19
Ji-Young Choi, Ye Jin Kim, Ri Ryu, Su-Jung Cho, Eun-Young Kwon, Myung-Sook Choi
Green tea (GT) has various health effects, including anti-obesity properties. However, the multiple molecular mechanisms of the effects have not been fully determined. The aim of this study was to elucidate the anti-obesity effects of GT via the analysis of its metabolic and transcriptional responses based on RNA-seq profiles. C57BL/6J mice were fed a normal, high-fat (60% energy as fat), or high-fat + 0.25% (w/w) GT diet for 12 weeks. The GT extract ameliorated obesity, hepatic steatosis, dyslipidemia, and insulin resistance in diet-induced obesity (DIO) mice...
October 14, 2016: Nutrients
https://www.readbyqxmd.com/read/27725410/the-combination-of-green-tea-extract-and-eriodictyol-inhibited-high-fat-high-sucrose-diet-induced-cholesterol-upregulation-is-accompanied-by-suppression-of-cholesterol-synthesis-enzymes
#20
Mai Yamashita, Motofumi Kumazoe, Yuki Nakamura, Yeong Seon Won, Jaehoon Bae, Shuya Yamashita, Hirofumi Tachibana
Western diets induce obesity associated with an increased risk of hypercholesterolaemia. Indeed, obesity-induced hypercholesterolaemia is correlated with increased coronary cardiovascular disease (CVD) risk. Male C57BL/6J mice were fed a normal diet, high-fat and high-sucrose diet (HF/HS), HF/HS with green tea extract powder diet (HF/HS+GT), HF/HS with eriodictyol diet (HF/HS+Eri), or HF/HS with green tea extract powder and eriodictyol diet (HF/HS+GT+Eri) for 8 wk. Body weight was lower in the HF/HS+GT+Eri group than in the HF/HS group (-8...
2016: Journal of Nutritional Science and Vitaminology
keyword
keyword
63151
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"