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https://www.readbyqxmd.com/read/27921383/consumption-of-the-total-western-diet-differentially-affects-the-response-to-green-tea-in-rodent-models-of-chronic-disease-compared-to-the-ain93g-diet
#1
Robert E Ward, Abby D Benninghoff, Brett J Healy, Minghao Li, Bharath Vagu, Korry J Hintze
SCOPE: In pre-clinical studies investigating bioactive components, the efficacy of the bioactive is likely influenced by the basal diet provided to rodents. In this study, we hypothesized that a model bioactive, green tea extract (GTE), would have different effects on colon carcinogenesis, body composition, and lipid metabolism in mice fed a basal diet formulated to promote animal health and growth (AIN93G) as compared to a Western diet that emulates typical American intakes of micro- and macronutrients, the total Western diet (TWD)...
December 6, 2016: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/27845787/the-effect-of-green-tea-polyphenols-on-gut-microbial-diversity-and-fat-deposition-in-c57bl-6j-hfa-mice
#2
Li Wang, Benhua Zeng, Xiaojing Zhang, Zhenlin Liao, Lihui Gu, Zhiwei Liu, Qingping Zhong, Hong Wei, Xiang Fang
Quantitative and qualitative changes in gut microbial composition have been linked to obesity and obesity-related complications, and eating pattern has been shown to significantly impact the gut microbiome. Meanwhile, tea polyphenols are known to have health benefits such as improving glucose tolerance and decreasing liver fat deposition that may be helpful in combating obesity and obesity-related disorders. We therefore studied the effect of green tea polyphenols on gut microbial diversity and fat deposition in C57BL/6J Human Flora-Associated (HFA) mice, which were divided into five groups: low fat (LF), high fat (HF), high fat + 0...
November 15, 2016: Food & Function
https://www.readbyqxmd.com/read/27812583/the-modulatory-effect-of-infusions-of-green-tea-oolong-tea-and-black-tea-on-gut-microbiota-in-high-fat-induced-obese-mice
#3
Zhibin Liu, Zhichao Chen, Hongwen Guo, Dongping He, Huiru Zhao, Zhiyao Wang, Wen Zhang, Lan Liao, Chen Zhang, Li Ni
Tea consumption has been identified to have an anti-obesity effect. Whether it is associated with gut microbiota modulation is investigated in this study. Phenolic profiles of infusions of green tea, oolong tea and black tea were comprehensively compared first, by utilizing ultra-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry (UPLC-ESI-Q-TOFMS). Subsequently, high-fat-diet induced obese C57BL/6J mice were orally administered these three types of tea infusions for 13 weeks to evaluate their anti-obesity and gut microbiota modulatory effects...
November 4, 2016: Food & Function
https://www.readbyqxmd.com/read/27806972/effects-of-green-tea-catechin-extract-on-serum-lipids-in-postmenopausal-women-a-randomized-placebo-controlled-clinical-trial
#4
Hamed Samavat, April R Newman, Renwei Wang, Jian-Min Yuan, Anna H Wu, Mindy S Kurzer
BACKGROUND: Green tea has been suggested to improve cardiovascular disease risk factors, including circulating lipid variables. However, current evidence is predominantly based on small, short-term randomized controlled trials conducted in diverse populations. OBJECTIVE: The aim of this study was to examine the efficacy and impact of green tea extract (GTE) supplementation high in epigallocatechin gallate (EGCG) on blood lipids in healthy postmenopausal women. DESIGN: This was an ancillary study of a double-blind, randomized, placebo-controlled, parallel-arm trial investigating the effects of a GTE supplement containing 1315 mg catechins (843 mg EGCG) on biomarkers of breast cancer risk...
November 2, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27797683/short-term-effects-of-green-tea-on-blood-pressure-endothelial-function-and-metabolic-profile-in-obese-prehypertensive-women-a-crossover-randomized-clinical-trial
#5
Lívia de P Nogueira, José Firmino Nogueira Neto, Márcia R S T Klein, Antonio F Sanjuliani
BACKGROUND: Green tea consumption has been inversely associated with cardiovascular disease (CVD) in epidemiological studies. Although some interventional trials suggest that green tea has beneficial effects on CVD risk factors, such as hypertension and obesity, others have failed to show such benefits. AIMS: To evaluate the short-term effects of green tea on blood pressure, endothelial function, metabolic profile, and inflammatory activity in obese prehypertensive women...
October 31, 2016: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/27754422/effect-of-green-tea-extract-on-systemic-metabolic-homeostasis-in-diet-induced-obese-mice-determined-via-rna-seq-transcriptome-profiles
#6
Ji-Young Choi, Ye Jin Kim, Ri Ryu, Su-Jung Cho, Eun-Young Kwon, Myung-Sook Choi
Green tea (GT) has various health effects, including anti-obesity properties. However, the multiple molecular mechanisms of the effects have not been fully determined. The aim of this study was to elucidate the anti-obesity effects of GT via the analysis of its metabolic and transcriptional responses based on RNA-seq profiles. C57BL/6J mice were fed a normal, high-fat (60% energy as fat), or high-fat + 0.25% (w/w) GT diet for 12 weeks. The GT extract ameliorated obesity, hepatic steatosis, dyslipidemia, and insulin resistance in diet-induced obesity (DIO) mice...
October 14, 2016: Nutrients
https://www.readbyqxmd.com/read/27725410/the-combination-of-green-tea-extract-and-eriodictyol-inhibited-high-fat-high-sucrose-diet-induced-cholesterol-upregulation-is-accompanied-by-suppression-of-cholesterol-synthesis-enzymes
#7
Mai Yamashita, Motofumi Kumazoe, Yuki Nakamura, Yeong Seon Won, Jaehoon Bae, Shuya Yamashita, Hirofumi Tachibana
Western diets induce obesity associated with an increased risk of hypercholesterolaemia. Indeed, obesity-induced hypercholesterolaemia is correlated with increased coronary cardiovascular disease (CVD) risk. Male C57BL/6J mice were fed a normal diet, high-fat and high-sucrose diet (HF/HS), HF/HS with green tea extract powder diet (HF/HS+GT), HF/HS with eriodictyol diet (HF/HS+Eri), or HF/HS with green tea extract powder and eriodictyol diet (HF/HS+GT+Eri) for 8 wk. Body weight was lower in the HF/HS+GT+Eri group than in the HF/HS group (-8...
2016: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/27722362/molecular-mechanisms-of-the-anti-obesity-effect-of-bioactive-compounds-in-tea-and-coffee
#8
Min-Hsiung Pan, Yen-Chen Tung, Guliang Yang, Shiming Li, Chi-Tang Ho
Obesity is a serious health problem in adults and children worldwide. However, the basic strategies for the management of obesity (diet, exercise, drugs and surgery) have limitations and side effects. Therefore, many researchers have sought to identify bioactive components in food. Tea and coffee are the most frequently consumed beverages in the whole world. Their health benefits have been studied for decades, especially those of green tea. The anti-obesity effect of tea and coffee has been studied for at least ten years...
October 10, 2016: Food & Function
https://www.readbyqxmd.com/read/27698343/green-tea-reduces-body-fat-via-upregulation-of-neprilysin
#9
M Muenzner, N Tappenbeck, F Gembardt, R Rülke, J Furkert, M F Melzig, W-E Siems, G A Brockmann, T Walther
BACKGROUND/OBJECTIVE: Consumption of green tea has become increasingly popular, particularly because of claimed reduction in body weight. We recently reported that animals with pharmacological inhibition (by candoxatril) or genetic absence of the endopeptidase neprilysin (NEP) develop an obese phenotype. We now investigated the effect of green tea extract (in drinking water) on body weight and body composition and the mediating role of NEP. SUBJECTS/METHODS: To elucidate the role of NEP in mediating the beneficial effects of green tea extract, 'Berlin fat mice' or NEP-deficient mice and their age- and gender-matched wild-type controls received the extract in two different doses (300 or 600 mg kg(-1) body weight per day) in the drinking water...
November 8, 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27689985/beneficial-effects-of-tea-and-the-green-tea-catechin-epigallocatechin-3-gallate-on-obesity
#10
Takuji Suzuki, Monira Pervin, Shingo Goto, Mamoru Isemura, Yoriyuki Nakamura
Green tea has been shown to have beneficial effects against cancer, obesity, atherosclerosis, diabetes, bacterial and viral infections, and dental caries. The catechin (-)-epigallocatechin-3-gallate (EGCG) has shown the highest biological activity among green tea catechins (GTCs) in most of the studies. While several epidemiological studies have shown the beneficial effects of tea and GTCs on obesity, some studies have failed to do this. In addition, a large number of interventional clinical studies have shown these favorable effects, and cellular and animal experiments have supported those findings, and revealed the underlying anti-obesity mechanisms...
September 29, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27634207/anti-inflammatory-action-of-green-tea
#11
Tomokazu Ohishi, Shingo Goto, Pervin Monira, Mamoru Isemura, Yoriyuki Nakamura
BACKGROUND: Green tea has been shown to have beneficial effects against a variety of diseases such as cancer, obesity, diabetes, cardiovascular disease, and neurodegenerative diseases. Through cellular, animal, and human experiments, green tea and its major component, epigallocatechin-3-gallate (EGCG) have been demonstrated to have anti-inflammatory effects. Our previous findings have indicated that green tea and EGCG suppress the gene and/or protein expression of inflammatory cytokines and inflammation-related enzymes...
September 15, 2016: Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/27600055/green-tea-extract-and-catechol-o-methyltransferase-genotype-modify-the-post-prandial-serum-insulin-response-in-a-randomised-trial-of-overweight-and-obese-post-menopausal-women
#12
A M Dostal, A Arikawa, L Espejo, S Bedell, M S Kurzer, N R Stendell-Hollis
BACKGROUND: Green tea extract (GTE) may be involved in a favourable post-prandial response to high-carbohydrate meals. The catechol-O-methyltransferase (COMT) genotype may modify these effects. We examined the acute effects of GTE supplementation on the post-prandial response to a high-carbohydrate meal by assessing appetite-associated hormones and glucose homeostasis marker concentrations in women who consumed 843 mg of (-)-epigallocatechin-3-gallate (EGCG) or placebo capsules for 11-12 months...
September 7, 2016: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/27528497/immobilized-tannase-treatment-alters-polyphenolic-composition-in-teas-and-their-potential-anti-obesity-and-hypoglycemic-activities-in-vitro
#13
Bruna Sampaio Roberto, Gabriela Alves Macedo, Juliana Alves Macedo, Isabela Mateus Martins, Vânia Mayumi Nakajima, J William Allwood, Derek Stewart, Gordon J McDougall
The aim of this work was to assess the effect of immobilized-tannase treatment on black, green, white and mate tea components and on their bioactivities relevant to obesity. Tannase treatment caused predictable changes in polyphenol composition with substantial reduction in galloylated catechins in green, white and black tea. Mate tea, which is rich in chlorogenic acids, was much less affected by tannase treatment although some degradation of caffeoyl quinic acid derivatives was noted. The original tea samples were effective in inhibiting digestive enzymes in vitro...
September 14, 2016: Food & Function
https://www.readbyqxmd.com/read/27489005/consumption-of-walnuts-in-combination-with-other-whole-foods-produces-physiologic-metabolic-and-gene-expression-changes-in-obese-c57bl-6j-high-fat-fed-male-mice
#14
Ting Luo, Omar Miranda-Garcia, Allysa Adamson, Jill Hamilton-Reeves, Debra K Sullivan, Jason M Kinchen, Neil F Shay
BACKGROUND: Although a reductionist approach has sought to understand the roles of individual nutrients and biochemicals in foods, it has become apparent that there can be differences when studying food components in isolation or within the natural matrix of a whole food. OBJECTIVE: The objective of this study was to determine the ability of whole-food intake to modulate the development of obesity and other metabolic dysfunction in mice fed a high-fat (HF), Western-style obesogenic diet...
September 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/27468160/green-tea-epigallocatechin-3-gallate-counteracts-daytime-overeating-induced-by-high-fat-diet-in-mice
#15
Hongyu Li, Huiling Calvina Kek, Joy Lim, Richard Wayne Gelling, Weiping Han
SCOPE: High-fat diet (HFD) induces overeating and obesity. Green tea (-)-epigallocatechin-3-gallate (EGCG) reduces HFD-induced body weight and body fat gain mainly through increased lipid metabolism and fat oxidation. However, little is known about its effect on HFD-induced alterations in feeding behavior. METHODS AND RESULTS: Three diet groups of wildtype C57B/6j male mice at 5 months old were fed on normal chow diet (NCD), one week of HFD (60% of energy) and three months of HFD (diet-induced obesity, DIO) prior to EGCG supplement in respective diet...
July 28, 2016: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/27465483/usage-of-plant-food-supplements-pfs-for-weight-control-in-six-european-countries-results-from-the-plantlibra-pfs-consumer-survey-2011-2012
#16
Alicia Garcia-Alvarez, Raimon Mila-Villarroel, Lourdes Ribas-Barba, Bernadette Egan, Mihaela Badea, Franco M Maggi, Maija Salmenhaara, Patrizia Restani, Lluis Serra-Majem
BACKGROUND: Obesity is increasing worldwide and weight-control strategies, including the consumption of plant food supplements (PFS), are proliferating. This article identifies the herbal ingredients in PFS consumed for weight control and by overweight/obese dieters in six European countries, and explores the relationship between their consumption and their self-reported BMI. METHODS: Data used were a subset from the PlantLIBRA PFS Consumer Survey 2011-2012, a retrospective survey of 2359 PFS consumers...
2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27450231/effects-of-greenselect-phytosome%C3%A2-on-weight-maintenance-after-weight-loss-in-obese-women-a-randomized-placebo-controlled-study
#17
Luisa Gilardini, Lucia Pasqualinotto, Francesco Di Pierro, Paolo Risso, Cecilia Invitti
BACKGROUND: Most subjects regain weight after weight loss due to compensatory adaptations finalized to maintain stable body energy stores. Green tea (GT) preparations, which help maintain energy expenditure while dieting could be a useful strategy to facilitate weight maintenance. The usefulness of GT preparations in weight maintenance has been poorly studied so far with conflicting results. This study evaluated if a supplement of GSP and piperine helps obese women to maintain the weight loss obtained with a 3-month lifestyle intervention...
July 22, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27443447/therapeutic-potential-of-green-tea-on-risk-factors-for-type-2-diabetes-in-obese-adults-a-review
#18
REVIEW
M A Ferreira, D M Silva, A C de Morais, J F Mota, P B Botelho
Green tea has been associated with positive effects in the treatment of obesity and other associated comorbidities such as type 2 diabetes. These benefits are thought to be related to the anti-inflammatory and antioxidant effects of green tea and to the reduction in body fat percentage exhibited by its bioactive compounds. The predominant active compounds in green tea are flavonoid monomers known as catechins, in particular epigallocatechin-3-gallate, which is the most abundant and most effective catechin in metabolic care, particularly among obese patients...
December 2016: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27397998/epigallocatechin-gallate-inhibits-mouse-mesenchymal-stem-cell-differentiation-to-adipogenic-lineage
#19
Baldeep Chani, Veena Puri, Ranbir Chander Sobti, Sanjeev Puri
Epigallocatechin gallate (EGCG) is a major component of green tea polyphenols having a potent anti-oxidant potential. Besides inhibiting the growth of many cancer cell types and inducing proliferation and differentiation in keratinocytes, it has been shown to promote reduction of body fat. The fact that mesenchymal stem cells (MSCs) have ability to self-renew and differentiate into the cells of mesodermal lineages, such as fat and bone, it is, thus, possible that EGCG may directly be involved in affecting fat metabolism through its effect on mesenchymal stem cells...
2016: Journal of Stem Cells & Regenerative Medicine
https://www.readbyqxmd.com/read/27324590/systematic-review-of-green-tea-epigallocatechin-gallate-in-reducing-low-density-lipoprotein-cholesterol-levels-of-humans
#20
Yuko Momose, Mari Maeda-Yamamoto, Hiroshi Nabetani
We conducted a systematic review of the literature for the ability of green tea epigallocatechin gallate (EGCG) to lower low-density lipoprotein cholesterol (LDL-C). Study subjects were limited to healthy individuals and randomized, controlled trials on human serum lipid levels, especially LDL-C, conducted. A total of 17 trials (n = 1356) met all of the inclusion criteria. According to weighted mean differences for changes from baseline with 95% confidence intervals (CI), 107-856 mg/d of EGCG for 4 to 14 weeks reduced LDL-C by -9...
September 2016: International Journal of Food Sciences and Nutrition
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