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https://www.readbyqxmd.com/read/29280418/comparative-effect-of-camellia-sinensis-teas-on-object-recognition-test-deficit-and-metabolic-changes-induced-by-cafeteria-diet
#1
Melina Bucco Soares, Juliana Bernera Ramalho, Aryele Pinto Izaguirry, Natasha Frasson Pavin, Cristiano Chiapinotto Spiazzi, Helen Lidiane Schimidt, Pâmela Billig Mello-Carpes, Francielli Weber Santos
OBJECTIVES: Consumption of high-fat and high-sugar diets in Western countries has increased significantly causing major global health problems including metabolic syndrome and obesity. In addition, studies have suggested that obesity can lead to learning and memory deficits. In this context, the use of natural compounds with low costs, minor side effects and increased antioxidant activity, such as teas, could reduce the damages induced by obesity. We investigated the effect of white, green, red, and black teas (Camellia sinensis) and their possible neuroprotective mechanisms in an experimental obesity model induced by a cafeteria diet (CD)...
December 27, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/29232928/beverage-consumption-patterns-among-overweight-and-obese-african-american-women
#2
Terryl J Hartman, Regine Haardörfer, Brenda M Greene, Shruti Parulekar, Michelle C Kegler
The goal of this research was to assess patterns of beverage consumption and the contribution of total beverages and classes of beverages to overall energy intake and weight status. We conducted an analysis in a community-based study of 280 low-income overweight and obese African American women residing in the rural South. Participants provided baseline data including demographic characteristics, weight and two 24-h food and beverage dietary recalls. Mean energy intake from beverages was approximately 273 ± 192 kcal/day or 18...
December 11, 2017: Nutrients
https://www.readbyqxmd.com/read/29228755/long-term-supplementation-of-decaffeinated-green-tea-extract-does-not-modify-body-weight-or-abdominal-obesity-in-a-randomized-trial-of-men-at-high-risk-for-prostate-cancer
#3
Nagi B Kumar, Roshni Patel, Julio Pow-Sang, Philippe E Spiess, Raoul Salup, Christopher R Williams, Michael J Schell
Background: Evidence continues to demonstrate the role of obesity in prostate carcinogenesis and prognosis, underscoring the need to identify and continue to evaluate the effective interventions to reduce obesity in populations at high risk. The aim of the study was to determine the effect of daily consumption of decaffeinated green tea catechins (GTC) formulation (Polyphenon E® (PolyE)) for 1 year on biomarkers of obesity in men who are at high risk for prostate cancer. Materials and Methods: A randomized, double-blinded trial was conducted targeting 97 men diagnosed with HGPIN or ASAP...
November 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29190550/green-tea-extract-protects-against-hepatic-nf%C3%AE%C2%BAb-activation-along-the-gut-liver-axis-in-diet-induced-obese-mice-with-nonalcoholic-steatohepatitis-by-reducing-endotoxin-and-tlr4-myd88-signaling
#4
Jinhui Li, Geoffrey Y Sasaki, Priyankar Dey, Chureeporn Chitchumroonchokchai, Allison N Labyk, Joshua D McDonald, Joshua B Kim, Richard S Bruno
Green tea extract (GTE) reduces NFκB-mediated inflammation during nonalcoholic steatohepatitis (NASH). We hypothesized that its anti-inflammatory activities would be mediated in a Toll-like receptor 4 (TLR4)-dependent manner. Wild-type (WT) and loss-of-function TLR4-mutant (TLR4m) mice were fed a high-fat diet containing GTE at 0 or 2% for 8 weeks before assessing NASH, NFκB-mediated inflammation, TLR4 and its adaptor proteins MyD88 and TRIF, circulating endotoxin, and intestinal tight junction protein mRNA expression...
November 3, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29175576/potential-role-of-the-mitochondria-as-a-target-for-the-hepatotoxic-effects-of-epigallocatechin-3-gallate-in-mice
#5
Karma D James, Mary J Kennett, Joshua D Lambert
Green tea and (-)-epigallocatechin-3-gallate (EGCG) have been studied for their obesity-related health effects. Many green tea extract (GTE)-based dietary supplements are commercially-available. Although green tea beverage has a long history of safe use, a growing number of case-reports have linked GTE-based supplements to incidents of hepatotoxicity. Animal studies support the hepatotoxic potential of GTE and EGCG, but the mechanisms remain unclear. Here, we examined the hepatotoxic effects of EGCG in C57BL/6J mice and evaluated changes in hepatic antioxidant response and mitochondria structure and function...
November 22, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29163391/colletotrichum-gloeosporioides-contaminated-tea-infusion-blocks-lipids-reduction-and-induces-kidney-damage-in-mice
#6
Jin Li, Kang Sun, Qingping Ma, Jin Chen, Le Wang, Dingjun Yang, Xuan Chen, Xinghui Li
When the homogenate of fresh tea tree leaves was fermented to produce black tea beverage, the Colletotrichum gloeosporioides (main pathogen or endophyte of Camellia sinensis) may be mixed into the fermentation liquor. However, it was unclear whether C. gloeosporioides-contaminated tea beverage would damage human health. Therefore, we investigated the changes of functional components and the influences on mice. C. gloeosporioides was added to the green tea infusion. After cultivation of 48 h, tea polyphenols, caffeine, and L-theanine decreased by 31...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29156939/phenolic-compounds-as-natural-and-multifunctional-anti-obesity-agents-a-review
#7
Celia Rodríguez-Pérez, Antonio Segura-Carretero, María Del Mar Contreras
Prevalence of obesity worldwide has reached pandemic proportions. Despite the increasing evidence in the implication of phenolic compounds in obesity management, the real effect is not completely understood. The available in vitro and in vivo studies have demonstrated the implication of phenolic compounds in: lowering food intake, decreasing lipogenesis, increasing lipolysis, stimulating fatty acids β-oxidation, inhibiting adipocyte differentiation and growth, attenuating inflammatory responses and suppress oxidative stress...
November 20, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29131612/functional-characterization-of-epitheaflagallin-3-o-gallate-generated-in-laccase-treated-green-tea-extracts-in-the-presence-of-gallic-acid
#8
Nobuya Itoh, Junji Kurokawa, Yasuhiro Isogai, Masaru Ogasawara, Takayuki Matsunaga, Tutomu Okubo, Yuji Katsube
Epitheaflagallin (ETFG) and epitheaflagallin 3-O-gallate (ETFGg) are minor polyphenols in black tea extract that are enzymatically synthesized from epigallocatechin (EGC) and epigallocatechin gallate (EGCg), respectively, in green tea extract via laccase oxidation in the presence of gallic acid. The constituents of laccase-treated green tea extract in the presence of gallic acid are thus quite different from those of non-laccase-treated green tea extract: EGC and EGCg are present in lower concentrations, and ETFG and ETFGg are present in higher concentrations...
November 13, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29129232/effect-of-green-tea-on-plasma-leptin-and-ghrelin-levels-a%C3%A2-systematic-review-and-meta-analysis-of-randomized-controlled-clinical-trials
#9
Fahimeh Haghighatdoost, B Fatemeh Nobakht M Gh, Mitra Hariri
OBJECTIVE: The purpose of this study was to conduct a meta-analysis of randomized controlled trials (RCTs) to assess the effect of green tea on serum leptin and ghrelin concentrations. METHODS: We searched PubMed, ISI Web of Science, Scopus, and Google scholar databases up to December 2016. The searches included RCTs conducted in human adults, and studies on the effect of green tea and green tea extract on serum leptin and ghrelin concentrations as outcome variables...
January 2018: Nutrition
https://www.readbyqxmd.com/read/29080460/chlorogenic-acid-cga-a-pharmacological-review-and-call-for-further-research
#10
REVIEW
Muhammad Naveed, Veghar Hejazi, Muhammad Abbas, Asghar Ali Kamboh, Ghulam Jilany Khan, Muhammad Shumzaid, Fawwad Ahmad, Daryoush Babazadeh, Xia FangFang, Faezeh Modarresi-Ghazani, Li WenHua, Zhou XiaoHui
Phenolic acids have recently gained substantial attention due to their various practical, biological and pharmacological effects. Chlorogenic Acid (CGA, 3-CQA) is a most abundant isomer among caffeoylquinic acid isomers (3-, 4-, and 5-CQA), that currently known as 5-CQA as per guidelines of IUPAC. It is one of the most available acids among phenolic acid compounds which can be naturally found in green coffee extracts and tea. CGA is an important and biologically active dietary polyphenol, playing several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension, free radicals scavenger and a central nervous system (CNS) stimulator...
January 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29078075/effect-of-green-tea-on-hepatic-lipid-metabolism-in-mice-fed-a-high-fat-diet
#11
Miso Nam, Myung-Sook Choi, Ji-Young Choi, Nami Kim, Min-Sun Kim, Sunhee Jung, Juyeon Kim, Do Hyun Ryu, Geum-Sook Hwang
Green tea (GT) is a widely consumed beverage with health benefits, including antiobesity effects; however, the efficacy of GT on lipid levels associated with obesity is not clearly understood. Here, we examined the impact of GT consumption on lipid metabolism in the livers of high-fat diet (HFD)-induced obese mice. We performed lipid profiling using ultraperformance liquid chromatography quadrupole time-of-flight mass spectrometry in C57BL/6J mice fed a normal diet (ND), HFD and HFD with GT for 12 weeks. The partial least squares discriminant analysis score plot showed a difference among the groups and revealed that the levels of several lipid metabolites were altered in mice fed HFD with GT...
September 19, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29065471/association-between-diet-quality-and-adiposity-in-the-atlantic-path-cohort
#12
Vanessa DeClercq, Yunsong Cui, Cynthia Forbes, Scott A Grandy, Melanie Keats, Louise Parker, Ellen Sweeney, Zhijie Michael Yu, Trevor J B Dummer
The aim of this study was to examine diet quality among participants in the Atlantic Partnership for Tomorrow's Health (PATH) cohort and to assess the association with adiposity. Data were collected from participants (n = 23,768) aged 35-69 years that were residents of the Atlantic Canadian provinces. Both measured and self-reported data were used to examine adiposity (including body mass index (BMI), abdominal obesity, waist-to-hip ratio and fat mass) and food frequency questionnaires were used to assess diet quality...
October 21, 2017: Nutrients
https://www.readbyqxmd.com/read/29018779/differential-tissue-specific-and-pathway-specific-anti-obesity-effects-of-green-tea-and-taeumjowitang-a-traditional-korean-medicine-in-mice
#13
Junil Kim, Sujin Park, Haein An, Ji-Young Choi, Myung-Sook Choi, Sang-Woon Choi, Seong-Jin Kim
BACKGROUND: Traditional medicines have been leveraged for the treatment and prevention of obesity, one of the fastest growing diseases in the world. However, the exact mechanisms underlying the effects of traditional medicine on obesity are not yet fully understood. METHODS: We produced the transcriptomes of epididymal white adipose tissue (eWAT), liver, muscle, and hypothalamus harvested from mice fed a normal diet, high-fat-diet alone, high-fat-diet together with green tea, or a high-fat-diet together with Taeumjowitang, a traditional Korean medicine...
September 2017: Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28965248/decaffeinated-green-and-black-tea-polyphenols-decrease-weight-gain-and-alter-microbiome-populations-and-function-in-diet-induced-obese-mice
#14
Susanne M Henning, Jieping Yang, Mark Hsu, Ru-Po Lee, Emma M Grojean, Austin Ly, Chi-Hong Tseng, David Heber, Zhaoping Li
PURPOSE: Decaffeinated green tea (GT) and black tea (BT) polyphenols inhibit weight gain in mice fed an obesogenic diet. Since the intestinal microflora is an important contributor to obesity, it was the objective of this study to determine whether the intestinal microflora plays a role in the anti-obesogenic effect of GT and BT. METHODS: C57BL/6J mice were fed a high-fat/high-sucrose diet (HF/HS, 32% energy from fat; 25% energy from sucrose) or the same diet supplemented with 0...
September 30, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28895793/food-stabilizing-antioxidants-increase-nutrient-bioavailability-in-the-in-vitro-model
#15
Magdalena Mika, Agnieszka Wikiera, Anna Antończyk, Maja Grabacka
OBJECTIVE: We investigated whether antioxidants may enhance bioavailability of lipids and carbohydrates and therefore increase the risk of obesity development. METHODS: We tested how supplementation with antioxidants (0.01% butylated hydroxytoluene [BHT], α-tocopherol, and green tea catechins) of a diet containing butter and wheat bread affects bioavailability of fats and carbohydrates. The absorption of the in vitro digested diet was estimated in the intestinal epithelia model of the Caco-2 cells cultured in Transwell chambers...
September 12, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28891395/effects-of-catechins-and-caffeine-on-the-development-of-atherosclerosis-in-mice
#16
Litong Liu, Izumi Nagai, Ying Gao, Yoshibumi Matsushima, Yoshichika Kawai, Kazutoshi Sayama
Atherosclerosis is one of the diseases related to metabolic syndrome which is caused by obesity. Previous reports have shown that green tea and its components have anti-obesity effect. We examined whether catechins and caffeine can prevent the development of atherosclerosis by oral administration, singly or in combination to the atherosclerosis model mice. Results demonstrated that the number of atherosclerotic regions in the aorta was significantly reduced by the combined treatment, and the atherosclerotic area was also improved...
October 2017: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/28863365/a-polyphenolic-extract-from-green-tea-leaves-activates-fat-browning-in-high-fat-diet-induced-obese-mice
#17
Audrey M Neyrinck, Laure B Bindels, Lucie Geurts, Matthias Van Hul, Patrice D Cani, Nathalie M Delzenne
Fat browning has emerged as an attractive target for the treatment of obesity and related metabolic disorders. Its activation leads to increased energy expenditure and reduced adiposity, thus contributing to a better energy homeostasis. Green tea extracts (GTEs) were shown to attenuate obesity and low-grade inflammation and to induce the lipolytic pathway in the white adipose tissue (WAT) of mice fed a high-fat diet. The aim of the present study was to determine whether the antiobesity effect of an extract from green tea leaves was associated with the activation of browning in the WAT and/or the inhibition of whitening in the brown adipose tissue (BAT) in HF-diet induced obese mice...
November 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28804438/green-tea-extract-induces-genes-related-to-browning-of-white-adipose-tissue-and-limits-weight-gain-in-high-energy-diet-fed-rat
#18
Li-Han Chen, Yi-Wen Chien, Chung-Tiang Liang, Ching-Hung Chan, Meng-Han Fan, Hui-Yu Huang
Background: A wealth of research has reported on the anti-obesity effects of green tea extract (GTE). Although browning of white adipose tissue (WAT) has been reported to attenuate obesity, no study has disclosed the effects of GTE on browning in Sprague Dawley rats. Objectives: The aims of the study were to investigate the effects of GTE on anti-obesity and browning, and their underlying mechanisms. Methods: Four groups of rats (n=10/group) were used including a normal diet with vehicle treatment, and a high-energy diet (HED) with vehicle or GTE by oral gavage at 77...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/28760074/redox-status-on-different-regions-of-the-central-nervous-system-of-obese-and-lean-rats-treated-with-green-tea-extract
#19
Rita Cassia Macedo, Eduardo Fernandes Bondan, Rosemari Otton
OBJECTIVES: The purpose of this study was to evaluate some indicators of redox status, and inflammation on different regions of the central nervous system (CNS) of obese rats treated with green tea (GT). We hypothesized that obesity could affect the redox balance in different brain regions due to the diverse nature of the cells as well as the selective neuronal vulnerability to oxidative stress, and GT could triggers benefits effects restoring the redox status. METHODS: Male Wistar rats were treated with GT by gavage (12 weeks/5 days/week; 500 mg/kg of body weight) and obesity was induced by cafeteria diet (8 weeks)...
July 31, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28739640/egcg-ameliorates-high-fat-and-high-fructose-induced-cognitive-defects-by-regulating-the-irs-akt-and-erk-creb-bdnf-signaling-pathways-in-the-cns
#20
Yashi Mi, Guoyuan Qi, Rong Fan, Qinglian Qiao, Yali Sun, Yuqi Gao, Xuebo Liu
Obesity, which is caused by an energy imbalance between calorie intake and consumption, has become a major international health burden. Obesity increases the risk of insulin resistance and age-related cognitive decline, accompanied by peripheral inflammation. (-)-Epigallocatechin-3-gallate (EGCG), the major polyphenol in green tea, possesses antioxidant, anti-inflammatory, and cardioprotective activities; however, few reports have focused on its potential effect on cognitive disorders. In this study, our goal was to investigate the protective effects of EGCG treatment on insulin resistance and memory impairment induced by a high-fat and high-fructose diet (HFFD)...
November 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
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