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https://www.readbyqxmd.com/read/28934268/the-physics-of-unwound-and-wound-strings-on-the-electric-guitar-applied-to-the-pitch-intervals-produced-by-tremolo-vibrato-arm-systems
#1
Jonathan A Kemp
The physics of wound and unwound strings on the electric guitar are presented here, and the pitch intervals produced by the movements of a Fender Stratocaster tremolo unit are explained. Predicted changes in pitch sensitivity of different strings are given, and experimentally verified, for changes in saddle height, the distance of string free to move behind the nut and ratio of diameters/masses of the core and windings of wound strings. Also, it is shown that changes to the gauge of strings (assuming the string tension is sufficient for linear behaviour and in absence of changes to other construction details) don't alter the pitch intervals produced by a given angle of tremolo arm use assuming the instrument is set up with the same sounding pitches and starting bridge angle...
2017: PloS One
https://www.readbyqxmd.com/read/28932082/effects-and-mechanism-of-adenovirus-mediated-phosphatase-and-tension-homologue-deleted-on-chromosome-ten-gene-on-collagen-deposition-in-rat-liver-fibrosis
#2
Shu-Rui Xie, Jun-Yan An, Li-Bo Zheng, Xiao-Xia Huo, Jian Guo, David Shih, Xiao-Lan Zhang
AIM: To evaluate the effects of phosphatase and tension homologue deleted on chromosome ten (PTEN) gene on collagen metabolism in hepatic fibrosis and the underlying mechanisms. METHODS: Rat primary hepatic stellate cells (HSCs) and human LX-2 cells were transfected with adenovirus containing cDNA constructs encoding wild-type PTEN (Ad-PTEN), PTEN mutant G129E gene (Ad-G129E), and RNA interference constructs targeting the PTEN sequence PTEN short hairpin RNA to up-regulate and down-regulate the expression of PTEN...
August 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28931856/complications-following-vaginal-mesh-procedures-for-stress-urinary-incontinence-an-8-year-study-of-92-246-women
#3
Kim Keltie, Sohier Elneil, Ashwani Monga, Hannah Patrick, John Powell, Bruce Campbell, Andrew J Sims
Complications of surgical mesh procedures have led to legal cases against manufacturers worldwide and to national inquiries about their safety. The aim of this study was to investigate the rate of adverse events of these procedures for stress urinary incontinence in England over 8 years. This was a retrospective cohort study of first-time tension-free vaginal tape (TVT), trans-obturator tape (TOT) or suprapubic sling (SS) surgical mesh procedures between April 2007 and March 2015. Cases were identified from the Hospital Episode Statistics database...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28931491/global-regional-and-national-burden-of-neurological-disorders-during-1990-2015-a-systematic-analysis-for-the-global-burden-of-disease-study-2015
#4
(no author information available yet)
BACKGROUND: Comparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study provides such information but does not routinely aggregate results that are of interest to clinicians specialising in neurological conditions. In this systematic analysis, we quantified the global disease burden due to neurological disorders in 2015 and its relationship with country development level...
September 15, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28930234/nonspecific-feelings-expected-and-experienced-during-or-immediately-after-electroacupuncture-a-pilot-study-in-a-teaching-situation
#5
David F Mayor, Lara S McClure, J Helgi Clayton McClure
BACKGROUND: Some feelings elicited by acupuncture-type interventions are "nonspecific", interpretable as resulting from the placebo effect, our own self-healing capacities-or, indeed, the flow of qi. Expectation is thought to contribute to these nonspecific effects. Here we describe the use of two innovative 20-item questionnaires (EXPre20 and EXPost20) in a teaching situation. METHODS: Respondents were acupuncture students or practitioners on electroacupuncture (EA) training courses (N = 68)...
April 8, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28924079/dynamic-surface-tension-of-heterogemini-surfactants-with-quaternary-ammonium-salt-and-gluconamide-or-sulfobetaine-headgroups
#6
Tomokazu Yoshimura, Kanae Nyuta
Dynamic surface tensions of two types of heterogemini surfactants with nonidentical hydrophilic headgroups consisting of a quaternary ammonium salt (cationic) and a gluconamide (nonionic) or sulfobetaine (zwitterionic) group were measured using the maximum bubble pressure method. For these compounds, effects of alkyl chain length, structure of the hydrophilic groups, and surfactant concentration were investigated using diffusion coefficients and parameter x. The parameter x is related to the difference between the energies of adsorption and desorption of the surfactant...
September 15, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28922690/wound-tension-and-closability-with-keystone-flaps-v-y-flaps-and-primary-closure-a-study-in-fresh-frozen-cadavers
#7
Lewis C Donovan, Charles D Douglas, Dirk Van Helden
BACKGROUND: Previous publications have implied that the keystone flap provides mechanical benefits compared to primary closure. This has not been objectively demonstrated. METHODS: Elliptical defects were created in 'fresh-frozen' cadaveric specimens. Two approaches were used to investigate the potential mechanical benefits of keystone flaps. Experiment 1 (wound closure): 18 defects were incrementally enlarged until they could not be closed primarily either with a single 'midpoint' suture or with a continuous suture...
September 18, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28922097/gender-differences-in-variables-associated-with-sleep-quality-in-chronic-tension-type-headache
#8
Margarita Cigarán-Méndez, Juan J Fernández-Muñoz, Esperanza Navarro-Pardo, Carmen Jiménez-Antona, Paula Parás-Bravo, Francisco Alburquerque-Sendín, César Fernández-De-Las-Peñas
We aimed to evaluate gender differences in the relationships between headache features, sleep quality, anxiety, depressive symptoms and burden of headache in 193 patients (73% women) with chronic tension type headache (CTTH). Sleep quality was assessed with the Pittsburgh Sleep Quality Index. Headache features were collected with a four-week diary. The Hospital Anxiety and Depression Scale was used to assess anxiety/depressive symptoms. Headache Disability Inventory was used to evaluate the burden of headache...
September 18, 2017: Women & Health
https://www.readbyqxmd.com/read/28922046/supraorbital-electrical-stimulation-in-management-of-chronic-type-tension-headache-a-randomized-controlled-study
#9
Nashwa S Hamed
BACKGROUND AND PURPOSE: Headache disorders are considered one of the ten most disabling conditions, for both males and females, according to the World Health Organization. Chronic type tension headache (CTTH) has a prevalence of 2-3% within the general population. The purpose of this research was to investigate the effect of stimulating noninvasively the trigeminal nerve in the supraorbital area (SOES) for treatment of CTTH. METHODS: In an 8-week period of intervention, 45 patients were divided equally into three groups...
September 18, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28916261/differential-involvement-of-l-and-t-type-ca-2-channels-store-operated-calcium-channel-trpc-and-rho-kinase-signaling-pathway-s-in-pgf2%C3%AE-induced-contractions-in-myometrium-of-non-pregnant-and-pregnant-buffaloes-bubalus-bubalis
#10
Abhishek Sharma, Udayraj P Nakade, Pooja Jaitley, Vipin Sharma, Soumen Choudhury, Satish Kumar Garg
This study unravels the differential involvement of calcium signaling pathway(s) in PGF2α-induced contractions in myometrium of non-pregnant and pregnant buffaloes. Compared to the myometrium of pregnant animals, myometrium of non-pregnant buffaloes was more sensitive to PGF2α-induced contractile effect as manifested by the changes in mean integral tension (MIT) and tonicity. However, phasic contraction was significantly more in myometrium of pregnant animals. The uterotonic effect of PGF2α was dependent on extracellular Ca(2+) and its influx through nifedipine-sensitive L-type Ca(2+) channels both in non-pregnant and pregnant animals, but T-type Ca(2+) channels play an additional role during pregnancy...
September 12, 2017: Prostaglandins & Other Lipid Mediators
https://www.readbyqxmd.com/read/28915917/translocation-of-molecular-chaperones-to-the-titin-springs-is-common-in-skeletal-myopathy-patients-and-affects-sarcomere-function
#11
Andreas Unger, Lisa Beckendorf, Pierre Böhme, Rudolf Kley, Marion von Frieling-Salewsky, Hanns Lochmüller, Rolf Schröder, Dieter O Fürst, Matthias Vorgerd, Wolfgang A Linke
Myopathies encompass a wide variety of acquired and hereditary disorders. The pathomechanisms include structural and functional changes affecting, e.g., myofiber metabolism and contractile properties. In this study, we observed increased passive tension (PT) of skinned myofibers from patients with myofibrillar myopathy (MFM) caused by FLNC mutations (MFM-filaminopathy) and limb-girdle muscular dystrophy type-2A due to CAPN3 mutations (LGMD2A), compared to healthy control myofibers. Because the giant protein titin determines myofiber PT, we measured its molecular size and the titin-to-myosin ratio, but found no differences between myopathies and controls...
September 15, 2017: Acta Neuropathologica Communications
https://www.readbyqxmd.com/read/28915484/spontaneous-vesicle-formation-and-vesicle-to-micelle-transition-of-sodium-2-ketooctanate-in-water
#12
Huifang Xu, Na Du, Yawen Song, Shue Song, Wanguo Hou
Single-tailed short-chain alkyl keto-acids/salts, a class of fatty acid/salt derivatives, such as sodium 2-ketooctanate (KOCOONa), are a kind of weakly acid/salt type amphiphiles and plausible prebiotic molecules, and the current understanding of their aggregation behavior in aqueous solutions is still limited. Herein, the aggregation behavior of KOCOONa in aqueous solution was studied by changing its concentration (C), using equilibrium surface tension, conductivity, and fluorescence measurements. The aggregates formed were characterized using freeze-fracture and cryogenic transmission electron microscopy, dynamic light scattering, atomic force microscopy, and confocal laser scanning microscopy...
September 7, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28910506/tainted-love-gothic-imaging-of-nurses-in-popular-culture
#13
Margaret Mcallister, Donna Lee Brien, Lorna Piatti-Farnell
AIMS: To discuss representations of nursing in popular culture using the Contemporary Gothic theory. BACKGROUND: Nursing is stereotypically known as a caring profession. Caring in both the natural and professional perspectives is inextricably attached to love and love, we are told, is universal. In popular culture, however, there are numerous examples of nurses being portrayed in ways where love - its expression and its practice - has been transgressed or tainted...
September 14, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28905376/hiv-and-headache-a-cross-sectional-study
#14
Pedro Augusto Sampaio Rocha-Filho, Rinailda Cascia Santos Torres, Ulisses Ramos Montarroyos
INTRODUCTION: The head and neck are the second most common locations for pain among HIV-positive individuals. Most studies were conducted among HIV patients at an advanced stage of the disease. METHODS: This was a cross-sectional study. Patients with HIV and CD4+ T lymphocyte counts >500 were included. Semi-structured interview, the Headache Impact Test (HIT-6), and the Hospital Anxiety and Depression Scale were used. RESULTS: Of the 119 cases included, 63% were men...
September 14, 2017: Headache
https://www.readbyqxmd.com/read/28905127/adhd-is-associated-with-migraine-a-systematic-review-and-meta-analysis
#15
REVIEW
Haitham Salem, David Vivas, Fei Cao, Iram F Kazimi, Antonio L Teixeira, Cristian P Zeni
An association between primary headaches and attention-deficit/hyperactivity disorder (ADHD) has long been suggested. Moreover, headache is regarded as a common side effect of stimulants, the most effective treatment for ADHD. So far, no systematic review has evaluated the potential association between ADHD and headache. We performed a systematic review of the literature and a meta-analysis of all reported studies on ADHD and primary headaches. Our analysis showed a positive association between ADHD and migraine (OR 1...
September 13, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28904210/membrane-mechanics-govern-spatiotemporal-heterogeneity-of-endocytic-clathrin-coat-dynamics
#16
N M Willy, J P Ferguson, S D Huber, S P Heidotting, E Aygün, S A Wurm, E Johnston-Halperin, M G Poirier, C Kural
Dynamics of endocytic clathrin-coated structures can be remarkably divergent across different cell types, cells within the same culture, or even distinct surfaces of the same cell. The origin of this astounding heterogeneity remains to be elucidated. Here, we show that cellular processes associated with changes in effective plasma membrane tension induce significant spatiotemporal alterations in endocytic clathrin coat dynamics. Spatiotemporal heterogeneity of clathrin coat dynamics is also observed during morphological changes taking place within developing multicellular organisms...
September 13, 2017: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/28902102/post-traumatic-spinal-hygroma-causing-cord-compression-in-type-iii-odontoid-fracture-with-vertical-atlantoaxial-instability
#17
Salvatore Russo, Antonio Belli, Andy Eynon, Ali Nader-Sepahi
STUDY DESIGN: Case report. OBJECTIVE: To report the first case in the literature of a traumatic cervical spine subdural cerebrospinal fluid (CSF) collection (hygroma) under tension causing cord compression. We suggest etiopathogenesis and modality of treatment. SUMMARY OF BACKGROUND DATA: Hygromas are subdural cranial CSF collection. A literature review showed no previous published case of post-traumatic spinal hygroma. This was a potential life-threatening sequelae of a high cervical injury that warranted early diagnosis and emergency treatment...
September 15, 2017: Spine
https://www.readbyqxmd.com/read/28900887/insomnia-in-tension-type-headache-a-population-based-study
#18
Jiyoung Kim, Soo-Jin Cho, Won-Joo Kim, Kwang Ik Yang, Chang-Ho Yun, Min Kyung Chu
BACKGROUND: Tension-type headache (TTH) represents the most common type of headache among the general population. Although such headaches are usually mild in severity, some individuals with TTH experience severe symptoms and psychiatric comorbidities. Such patients may also experience sleep disturbances, which have been associated with headache exacerbation. Nevertheless, information regarding the prevalence and impact of insomnia among individuals with TTH in a population-based setting is limited...
September 12, 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28900566/transversus-abdominis-elasticity-during-various-exercises-a-shear-wave-ultrasound-elastography-study
#19
Kuniaki Hirayama, Ryota Akagi, Yuki Moniwa, Junichi Okada, Hideyuki Takahashi
BACKGROUND: Although the transversus abdominis (TrA) is considered to play a significant role in maintaining trunk stability, there is little information regarding the type of exercise that best facilitates the development of tension in the TrA. Muscle elasticity shows a strong association with muscle tension. Shear wave ultrasound elastography provides a means by which the tension of TrA can be noninvasively estimated, by quantifying it's elasticity. PURPOSE: The purpose of this study was to examine the TrA elasticity during several exercises as measured by shear wave ultrasound elastography, and to determine which of the studied exercises demonstrated the greatest tension...
August 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28898058/mechanoregulation-of-sm22%C3%AE-transgelin
#20
Rong Liu, M Moazzem Hossain, Xuequn Chen, Jian-Ping Jin
SM22α, also named transgelin, is an actin filament-associated protein in smooth muscle and fibroblast. Three decades after discovery, the biological function of SM22α remains under investigation. Here we report a novel finding that the expression and degradation of SM22α/transgelin is regulated by mechanical tension. Following a mass spectrometry identification of SM22α degradation in isolated and tension-unloaded mouse aorta, we developed specific monoclonal antibodies to study the regulation of SM22α in human fetal lung myofibroblast line MRC-5 and primary cultures of neonatal mouse skin fibroblast...
September 12, 2017: Biochemistry
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