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Mandibular reconstruction

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https://www.readbyqxmd.com/read/28426184/alterations-in-mandibular-morphology-associated-with-glypican-1-and-glypican-3-gene-mutations
#1
M Mian, S Ranjitkar, G C Townsend, P J Anderson
OBJECTIVES: Glypican 1 (GPC1) and glypican 3 (GPC3) are bone co-regulators that act downstream in many of the signalling pathways associated with craniosynostosis. Morphometric data from GPC-knockout mice were analysed to determine whether elimination of GPC1 and GPC3 genes would alter mandibular morphology. SETTING AND SAMPLE POPULATION: The murine model included five male and five female mandibles in each of GPC1-knockout, GPC1/GPC3-knockout and wild-type (control) groups...
April 20, 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28419844/triple-cut-computer-aided-design-computer-aided-modeling-more-oncologic-safety-added-to-precise-mandible-modeling
#2
Vittorio Ramella, Alberto Franchi, Stefano Bottosso, Giancarlo Tirelli, Federico Cesare Novati, Zoran Marij Arnež
PURPOSE: Computer-aided design-computer-aided modeling (CAD-CAM) has become standard in mandibular reconstruction because it offers better outcomes. Occasionally, the reconstructive plans need to be changed intraoperatively and the custom-made prefabricated devices may become inadequate. We present an efficient adjunct to the standard CAD-CAM technique that resolves this problem. MATERIALS AND METHODS: Customized surgical devices with our "triple-cut" concept were used in 5 patients for mandibular reconstruction with free fibula flap (4 after mandibular resection for squamous cell carcinoma and 1 after mandibular osteoradionecrosis)...
March 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28418700/three-dimensional-analysis-of-upper-airway-morphology-in-skeletal-class-iii-patients-with-and-without-mandibular-asymmetry
#3
Xi Wen, Xiyu Wang, Shuqi Qin, Lorenzo Franchi, Yan Gu
OBJECTIVE: To compare the three-dimensional (3D) morphology of the upper airway in skeletal Class III patients with and without mandibular asymmetry and to investigate the possible underlying correlations between the morphology of the upper airway and mandibular deviation. MATERIALS AND METHODS: Cone-beam computed tomography images of 54 subjects with skeletal Class III malocclusion (ANB angle ≤ 0.4°, Wits ≤ -5.5°) were taken and 3D upper airway models were reconstructed using Dolphin 3D software...
April 18, 2017: Angle Orthodontist
https://www.readbyqxmd.com/read/28415545/engineering-bone-regeneration-with-novel-cell-laden-hydrogel-microfiber-injectable-calcium-phosphate-scaffold
#4
Yang Song, Chi Zhang, Ping Wang, Lin Wang, Chunyun Bao, Michael D Weir, Mark A Reynolds, Ke Ren, Liang Zhao, Hockin H K Xu
Cell-based tissue engineering is promising to create living functional tissues for bone regeneration. The implanted cells should be evenly distributed in the scaffold, be fast-released to the defect and maintain high viability in order to actively participate in the regenerative process. Herein, we report an injectable calcium phosphate cement (CPC) scaffold containing cell-encapsulating hydrogel microfibers with desirable degradability that could deliver cells in a timely manner and maintain cell viability...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28414873/influence-of-pharyngeal-airway-respiration-pressure-on-class-ii-mandibular-retrusion-in-children-a-computational-fluid-dynamics-study-of-inspiration-and-expiration
#5
T Iwasaki, H Sato, H Suga, Y Takemoto, E Inada, I Saitoh, K Kakuno, R Kanomi, Y Yamasaki
OBJECTIVES: To examine the influence of negative pressure of the pharyngeal airway on mandibular retraction during inspiration in children with nasal obstruction using the computational fluid dynamics (CFD) method. SETTING AND SAMPLE POPULATION: Sixty-two children were divided into Classes I, II (mandibular retrusion) and III (mandibular protrusion) malocclusion groups. MATERIAL AND METHODS: Cone-beam computed tomography data were used to reconstruct three-dimensional shapes of the nasal and pharyngeal airways...
May 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28412180/computational-fluid-dynamics-study-of-the-pharyngeal-airway-space-before-and-after-mandibular-setback-surgery-in-patients-with-mandibular-prognathism
#6
Y Yajima, M Oshima, T Iwai, H Kitajima, S Omura, I Tohnai
The purpose of this study was to investigate the relationship between the pressure drop in the pharyngeal airway space (ΔPPAS) and the minimum cross-sectional area (minCSA) of the pharyngeal airway before and after mandibular setback surgery using computational fluid dynamics, in order to prevent iatrogenic obstructive sleep apnoea. Eleven patients with mandibular prognathism underwent bilateral sagittal split osteotomy for mandibular setback. Three-dimensional models of the upper airway were reconstructed from preoperative and postoperative computed tomography images, and simulations were performed using computational fluid dynamics...
April 12, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28403102/mandibular-regeneration-after-immediate-load-dental-implant-in-a-periodontitis-patient-a-clinical-and-ultrastructural-case-report
#7
Maurizio Catinari, Manuel Scimeca, Massimo Amorosino, Mario Marini, Elena Bonanno, Virginia Tancredi
RATIONALE: In this case study, we characterized from radiographic, morphological and elemental point of view the mandibular reconstruction that occur in patients affects by periodontitis after application of endosseous titanium implants. In particular, we verified that the bone load applied by titanium implant was able to induce the mandibular osteogenic reconstruction. PATIENT CONCERN: A 57-year-old female active smoker with no contraindications for dental implants and 3 unstable dental prostheses, underwent open surgery for the application of endosseous titanium implants (BANP IMPLANT S...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28396232/treatment-of-osteomyelitis-a-case-for-disruption-of-the-affected-adjacent-periosteum
#8
J W Hudson, Austin P Daly, Michael Foster
PURPOSE: To evaluate the response of mandibular osteomyelitis treated by surgical decortication with disruption of the affected adjacent periosteum in concert with long-term targeted antibiotic therapy. The hypothesis is that, by removing the buccal cortical plate and disrupting the hypertrophically inflamed adjacent periosteum, the medullary bone will be brought in contact with bleeding tissue and circulating immunologic factors and antibiotics, which will promote definitive resolution...
March 18, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28390760/restricted-mandibular-movement-attributed-to-ossification-of-mandibular-depressors-and-medial-pterygoid-muscles-in-patients-with-fibrodysplasia-ossificans-progressiva-a-report-of-3-cases
#9
Tetsuko Okuno, Hitoshi Suzuki, Akio Inoue, Jingo Kusukawa
Fibrodysplasia ossificans progressiva (FOP) is an extremely rare genetic condition characterized by congenital malformation and progressive heterotopic ossification (HO) caused by a recurrent single nucleotide substitution at position 617 in the ACVR1 gene. As the condition progresses, HO leads to joint ankylosis, breathing difficulties, and mouth-opening restriction, and it can shorten the patient's lifespan. This report describes 3 cases of FOP confirmed by genetic testing in patients with restricted mouth opening...
March 16, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28389648/root-anatomy-and-canal-morphology-of-mandibular-first-premolars-in-a-chinese-population
#10
Lei Dou, Duojiao Li, Tingting Xu, Yin Tang, Deqin Yang
This study was to investigate root anatomy and root canal morphology of mandibular first premolars in a Chinese population. 178 human permanent mandibular first premolars extracted from a native Chinese population were collected, scanned using micro-computed tomography and reconstructed three-dimensionally. The number of roots and canals, canal configuration and radicular grooves were investigated. The root canal morphology was categorized according to Vertucci's criteria. The radicular grooves were scored according to the Arizona State University dental anthropology scoring system (ASUDAS), and the correlation between scores for radicular grooves and root canal morphology was analyzed...
April 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28386463/scaffold-degradation-during-bone-tissue-reconstruction-in-macaca-nemestrina-mandible
#11
REVIEW
Endang W Bachtiar, Lisa Rinanda Amir, Pradono Suhardi, Basril Abas
OBJECTIVE: To examine the degradation of three scaffolds composed of hydroxyapatite/tricalcium phosphate (HA/TCP) with 70∶30 ratio, HA/TCP with 50∶50 ratio, and HA/TCP/chitosan scaffold as analyzed by the RNA expression of matrix metalloprotease 2 (MMP2), interleukin 13 (IL13), and tartrate-resistant acid phosphatase (TRAP) genes. METHODS: The three tested scaffolds and dental pulp stromal cells (DPSCs) were transplanted into the mandibular bone defect of six young male Macaca nemestrina...
June 1, 2016: Interventional Medicine & Applied Science
https://www.readbyqxmd.com/read/28384463/desmoplastic-fibroma-of-the-mandible-in-a-pediatric-patient-a-case-report-of-resection-and-reconstruction-with-a-six-year-follow-up
#12
Hernán Ramírez Skinner, Alex Vargas, Antonieta Solar, Camila Foncea, Paula Astorga
Desmoplastic fibroma (DF) of bone is considered a benign but locally aggressive tumor of fibroblastic origin. DF is rare, representing less than 1% of all bone tumors. Approximately 84% of patients are younger than 30 years. DF has a slow but aggressive growth potential and can recur locally when it has not been completely excised. Complete resection is the treatment of choice to decrease recurrence and morbidity. Mandibular reconstruction is mandatory in pediatric patients to ensure correct craniofacial development...
March 14, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28365396/use-of-the-3d-surgical-modelling-technique-with-open-source-software-for-mandibular-fibula-free-flap-reconstruction-and-its-surgical-guides
#13
L Ganry, B Hersant, J Quilichini, P Leyder, J P Meningaud
INTRODUCTION: Tridimensional (3D) surgical modelling is a necessary step to create 3D-printed surgical tools, and expensive professional software is generally needed. Open-source software are functional, reliable, updated, may be downloaded for free and used to produce 3D models. Few surgical teams have used free solutions for mastering 3D surgical modelling for reconstructive surgery with osseous free flaps. We described an Open-source software 3D surgical modelling protocol to perform a fast and nearly free mandibular reconstruction with microvascular fibula free flap and its surgical guides, with no need for engineering support...
March 29, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28359016/reconstruction-of-mandible-a-fully-digital-workflow-from-visualized-iliac-bone-grafting-to-implant-restoration
#14
Taoran Tian, Tao Zhang, Quanquan Ma, Qi Zhang, Xiaoxiao Cai
PURPOSE: Although digital aids can help surgeons compensate for the shortcomings of traditional mandibular reconstruction techniques to perform surgery more precisely and effectively, the use of these digital techniques has often been fragmented, divided, and incomplete. This article describes the workflow of a fully digital mandibular reconstruction to explore the proper indications and discusses innovations based on the accuracy and effectiveness of digital techniques. MATERIALS AND METHODS: A restoration-oriented mandibular reconstruction was performed by applying different digital techniques...
March 7, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28358629/reconstruction-of-a-mandibular-segmental-defect-with-a-customized-3-dimensional-printed-titanium-prosthesis-in-a-cat-with-a-mandibular-osteosarcoma
#15
Julius M Liptak, Graham P Thatcher, Jonathan P Bray
CASE DESCRIPTION A 12-year-old neutered male domestic shorthair cat had been treated for a mass arising from the lingual aspect of the caudal right mandibular body. Cytoreductive surgery of the mass had been performed twice over a 2-year period, but the mass recurred following both surgeries. The mass was diagnosed as an osteosarcoma, and the cat was referred for further evaluation and treatment. CLINICAL FINDINGS Clinical findings were unremarkable, except for a 2-cm-diameter mass arising from the lingual aspect of the right mandible and mild anemia and lymphopenia...
April 15, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28351395/follicular-thyroid-carcinoma-metastasis-to-the-facial-skeleton-a-systematic-review
#16
Varun V Varadarajan, Elizabeth K Pace, Vatsal Patel, Raja Sawhney, Robert J Amdur, Peter T Dziegielewski
BACKGROUND: Follicular thyroid carcinoma (FTC) metastasis to the facial skeleton is exceedingly rare. A case of FTC metastasizing to the mandible is presented and a systematic review of the literature describing thyroid metastasis to the facial skeleton is performed. CASE PRESENTATION: A 73-year-old female presented with metastatic FTC to the mandible and underwent total thyroidectomy, segmental mandibulectomy, bone impacted fibular free flap reconstruction, and adjuvant radioactive iodine treatment...
March 28, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28350556/resorbable-plates-prevent-regression-in-pediatric-mandibular-distraction-osteogenesis
#17
Brandon Kikuo Richland, Christopher Ellstrom, Asim Ahmad, Daniel Jaffurs
BACKGROUND: Mandibular distraction osteogenesis is an important technique to correct the pediatric hypoplastic mandible. Regression of the mandible after distraction continues to be a challenge, with some studies reporting up to 22% to 56% decrease toward predistraction length in the first year. We hypothesize that a resorbable plate placed after removal of the distractor will provide additional stability to newly formed bone, allowing further time for consolidation and minimizing regression...
May 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28350523/comparison-of-micro-ct-and-cone-beam-ct-on-the-feasibility-of-assessing-mandibular-trabecular-structures-in-mandibular-condyle
#18
Xin Liang, Zuyan Zhang, Jianping Gu, Zhihui Wang, Bart Vandenberghe, Reinhilde Jacobs, Jie Yang, Guowu Ma, Haibin Ling, Xuchen Ma
OBJECTIVES: To evaluate the accuracy of Cone-beam CT (CBCT) in assessing trabecular structures Methods: Two human mandibles were scanned by micro-CT (Skyscan 1173 high energy spiral scan micro-CT, Skyscan NV, Kontich, Belgium) and CBCT(3D Accuitomo 170, Morita Japan). The CBCT images were reconstructed in 0.5mm and 1 mm thickness. The condylar images were selected for registration. A parallel algorithm for histogram computation was introduced to perform the registration. Mutual information (MI) value was used to evaluate the match between the images obtained from micro-CT and CBCT...
March 28, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28349601/guided-bone-regeneration-of-non-contained-mandibular-buccal-bone-defects-using-deproteinized-bovine-bone-mineral-and-a-collagen-membrane-an-experimental-in%C3%A2-vivo-investigation
#19
Mariano Sanz, Luca Ferrantino, Fabio Vignoletti, Massimo de Sanctis, Tord Berglundh
AIM: The aim of this pre-clinical in vivo study was to analyse different stages of wound healing after guided bone regeneration in non-contained mandibular buccal bone defects. MATERIALS AND METHODS: Eighteen female beagle dogs, between 1.5 and 2 years old, were used. Buccal bone defects were created in the mandible following extraction of the mesial roots of M1, P4, the distal root of P3 and booth roots of P2. Augmentation procedures of the healed defects were performed 3 months later using a bone replacement graft (T1), an absorbable collagen membrane (T2) or a combination of both procedures (T3)...
March 27, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28347627/simulation-guided-navigation-for-vector-control-in-pediatric-mandibular-distraction-osteogenesis
#20
Giovanni Badiali, Fabrizio Cutolo, Andrea Roncari, Claudio Marchetti, Alberto Bianchi
AIM: Navigation technology has given surgeons the capacity to know precisely where their instruments are during surgery, and simulation-guided navigation is a surgical method which is based on the use of navigation technology linked to 3D virtual surgery simulation. The aim of the present study was to evaluate the absolute accuracy of simulation-guided navigation as an aid to reproduce the planned position of the distraction device vector in pediatric mandibular distraction osteogenesis...
February 14, 2017: Journal of Cranio-maxillo-facial Surgery
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