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3D Anatomy

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https://www.readbyqxmd.com/read/28808803/a-prototype-educational-model-for-hepatobiliary-interventions-unveiling-the-role-of-graphic-designers-in-medical-3d-printing
#1
Ramin Javan, Merissa N Zeman
In the context of medical three-dimensional (3D) printing, in addition to 3D reconstruction from cross-sectional imaging, graphic design plays a role in developing and/or enhancing 3D-printed models. A custom prototype modular 3D model of the liver was graphically designed depicting segmental anatomy of the parenchyma containing color-coded hepatic vasculature and biliary tree. Subsequently, 3D printing was performed using transparent resin for the surface of the liver and polyamide material to develop hollow internal structures that allow for passage of catheters and wires...
August 14, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28807205/facilitating-surgeon-understanding-of-complex-anatomy-using-a-three-dimensional-printed-model
#2
Barrett P Cromeens, William C Ray, Brad Hoehne, Fikir Abayneh, Brent Adler, Gail E Besner
BACKGROUND: 3-dimensional prints (3DP) anecdotally facilitate surgeon understanding of anatomy and decision-making. However, the actual benefit to surgeons or patients has not been quantified. This study investigates how surgeon understanding of complex anatomy is altered by a 3DP compared to computed tomography (CT) scan or CT + digital reconstruction (CT + DR). MATERIALS AND METHODS: Key anatomic features were segmented from a CT-abdomen/pelvis of pygopagus twins to build a DR and printed in color on a 3D printer...
August 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28802742/the-challenges-of-measuring-in-vivo-knee-collateral-ligament-strains-using-ultrasound
#3
Laura C Slane, Josh A Slane, Jan D'hooge, Lennart Scheys
Ultrasound-based methods have shown promise in their ability to characterize non-uniform deformations in large energy-storing tendons such as the Achilles and patellar tendons, yet applications to other areas of the body have been largely unexplored. The noninvasive quantification of collateral ligament strain could provide an important clinical metric of knee frontal plane stability, which is relevant in ligament injury and for measuring outcomes following total knee arthroplasty. In this pilot cadaveric experiment, we investigated the possibility of measuring collateral ligament strain with our previously validated speckle-tracking approach, but encountered a number of challenges during both data acquisition and processing...
July 31, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28800987/dynamic-three-dimensional-geometry-of-the-aortic-valve-apparatus-a-feasibility-study
#4
Arash Khamooshian, Yannis Amador, Ting Hai, Jelliffe Jeganathan, Maria Saraf, Eitezaz Mahmood, Robina Matyal, Kamal R Khabbaz, Massimo Mariani, Feroze Mahmood
OBJECTIVE: To provide (1) an overview of the aortic valve (AV) apparatus anatomy and nomenclature, and (2) data regarding the normal AV apparatus geometry and dynamism during the cardiac cycle obtained from three-dimensional transesophageal echocardiography (3D TEE). DESIGN: Retrospective feasibility study. SETTING: A single-center university teaching hospital. PARTICIPANTS: The study was performed on data of 10 patients with a nonregurgitant, nonstenotic aortic valve undergoing cardiac surgery...
August 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28798376/3d-biomimetic-artificial-bone-scaffolds-with-dual-cytokines-spatiotemporal-delivery-for-large-weight-bearing-bone-defect-repair
#5
Xiaogang Bao, Lingjun Zhu, Xiaodong Huang, Dezhi Tang, Dannong He, Jiangang Shi, Guohua Xu
It is a great challenge to prepare "functional artificial bone" for the repair of large segmental defect, especially in weight-bearing bones. In this study, bioactive HA/PCL composite scaffolds that possess anatomical structure as autogenous bone were fabricated by CT-guided fused deposition modeling technique. The scaffolds can provide mechanical support and possess osteoconduction property. Then the VEGF-165/BMP-2 loaded hydrogel was filled into biomimetic artificial bone spatially to introduce osteoinduction and angioinduction ability via sustained release of these cytokines...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28797120/medication-eluting-devices-for-the-field-of-obgyn-medobgyn-3d-printed-biodegradable-hormone-eluting-constructs-a-proof-of-concept-study
#6
Karthik Tappa, Udayabhanu Jammalamadaka, David H Ballard, Todd Bruno, Marissa R Israel, Harika Vemula, J Mark Meacham, David K Mills, Pamela K Woodard, Jeffery A Weisman
3D printing has the potential to deliver personalized implants and devices for obstetric and gynecologic applications. The aim of this study is to engineer customizable and biodegradable 3D printed implant materials that can elute estrogen and/or progesterone. All 3D constructs were printed using polycaprolactone (PCL) biodegradable polymer laden with estrogen or progesterone and were subjected to hormone-release profile studies using ELISA kits. Material thermal properties were tested using thermogravimetric analysis and differential scanning calorimetry...
2017: PloS One
https://www.readbyqxmd.com/read/28777285/3d-modeling-of-lower-extremities-with-biplanar-radiographs-reliability-of-measures-on-subsequent-examinations
#7
David E Westberry, Ashley M Carpenter
BACKGROUND: Biplanar radiography with 3-dimensional (3D) modeling (EOS) provides a comprehensive assessment of lower limb alignment in an upright weight-bearing position with less radiation than conventional radiography. A study was performed to assess the consistency and reliability of 2 lower extremity 3D biplanar radiograph models created at least 1 year apart in a pediatric population. METHODS: All patients who had 2 lower extremity radiographic evaluations with EOS performed at visits a minimum of 1 year apart were reviewed...
August 2, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28774763/anatomic-dissection-of-arachnoid-membranes-encircling-the-pituitary-stalk-on-fresh-non-formalin-fixed-specimens-anatomo-radiologic-correlations-and-clinical-applications-in-craniopharyngioma-surgery
#8
P Ciappetta, L Pescatori
BACKGROUND: The anatomy of the arachnoid membranes and cisternal spaces around the pituitary stalk has not been yet exhaustively described and understood. In this study we performed a detailed anatomic study on fresh non formalin fixed cadavers of the arachnoid membranes encircling the pituitary stalk and correlate our anatomic findings with MRI. METHODS: Ten fresh, non formalin-fixed non silicon-injected adult cadaveric heads were analyzed in this study. The membrane and cisterns that have been studied for our study are: - The diaphragma sellae and its dural components; - The basal arachnoid membrane; - The Lilequist's membrane with its diencephalic and mesencephalic portion; - The medial carotid membrane; - The chiasmatic cistern; - The pituitary stalk...
July 31, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28771144/effect-of-intra-fraction-motion-on-the-accumulated-dose-for-free-breathing-mr-guided-stereotactic-body-radiation-therapy-of-renal-cell-carcinoma
#9
Bjorn Stemkens, Markus Glitzner, Charis Kontaxis, Baudouin Denis de Senneville, Fieke M Prins, Sjoerd P M Crijns, Linda G W Kerkmeijer, Jan J W Lagendijk, Cornelis A T Van den Berg, Rob H N Tijssen
Stereotactic body radiation therapy (SBRT) has shown great promise in increasing local control rates for renal-cell carcinoma (RCC). Characterized by steep dose gradients and high fraction doses, these hypo-fractionated treatments are, however, prone to dosimetric errors as a result of variations in intra-fraction respiratory-induced motion, such as drifts and amplitude alterations. This may lead to significant variations in the deposited dose. This study aims to develop a method for calculating the accumulated dose for MRI-guided SBRT of RCC in the presence of intra-fraction respiratory variations and determine the effect of such variations on the deposited dose...
August 3, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28768118/an-imaged-based-three-dimensional-study-of-first-metatarsal-protrusion-distance-in-women-with-and-without-hallux-valgus
#10
Ward M Glasoe, Michael W Rodriguez, Kara E Pioske
BACKGROUND: First metatarsal protrusion distance (MPD) has been commonly studied as a characteristic of hallux valgus deformity. To date, the majority of investigations have used radiographic methods, with most reporting first metatarsal (ray) protrusion to be associated with deformity. As an alternative, this study used a three dimensional (3D) image acquisition and data analysis method to quantify MPD. METHODS: Magnetic resonance images were acquired in weightbearing on 29 women (19 with hallux valgus; 10 controls)...
August 2, 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28760089/feasibility-of-proton-pencil-beam-scanning-treatment-of-free-breathing-lung-cancer-patients
#11
Annika Jakobi, Rosalind Perrin, Antje Knopf, Christian Richter
BACKGROUND: The interplay effect might degrade the dose of pencil beam scanning proton therapy to a degree that free-breathing treatment might be impossible without further motion mitigation techniques, which complicate and prolong the treatment. We assessed whether treatment of free-breathing patients without motion mitigation is feasible. MATERIAL AND METHODS: For 40 lung cancer patients, 4DCT datasets and individual breathing patterns were used to simulate 4D dynamic dose distributions of 3D treatment plans over 33 fractions delivered with an IBA universal nozzle...
August 1, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28759705/validation-of-clay-modeling-as-a-learning-tool-for-the-periventricular-structures-of-the-human-brain
#12
Veronica Akle, Ricardo A Peña-Silva, Diego M Valencia, Carlos W Rincón-Perez
Visualizing anatomical structures and functional processes in three dimensions (3D) are important skills for medical students. However, contemplating 3D structures mentally and interpreting biomedical images can be challenging. This study examines the impact of a new pedagogical approach to teaching neuroanatomy, specifically how building a 3D-model from oil-based modeling clay affects learners' understanding of periventricular structures of the brain among undergraduate medical students in Colombia. Students were provided with an instructional video before building the models of the structures, and thereafter took a computer-based quiz...
July 31, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28756962/evaluation-of-different-techniques-for-filling-simulated-c-shaped-canals-of-3-dimensional-printed-resin-teeth
#13
Tuba Gok, Ismail Davut Capar, Ilgin Akcay, Ali Keles
INTRODUCTION: The purpose of this study was to compare the ability of different root canal filling methods on the C1 root canal anatomy using 3-dimensional (3D) printer technology. METHODS: Mandibular molars were scanned with cone-beam computed tomographic (CBCT) imaging. A mandibular molar tooth with a C1 root canal configuration was selected according to images obtained from CBCT technology. The root canals were shaped with ProTaper Universal rotary instruments (Dentsply Maillefer, Ballaigues, Switzerland) and hand files...
July 27, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28756622/fully-automatic-multi-organ-segmentation-in-normal-whole-body-magnetic-resonance-imaging-mri-using-classification-forests-cfs-convolutional-neural-networks-cnns-and-a-multi-atlas-ma-approach
#14
Ioannis Lavdas, Ben Glocker, Konstantinos Kamnitsas, Daniel Rueckert, Henrietta Mair, Amandeep Sandhu, Stuart A Taylor, Eric O Aboagye, Andrea G Rockall
PURPOSE: As part of a programme to implement automatic lesion detection methods for whole body magnetic resonance imaging (MRI) in oncology, we have developed, evaluated and compared three algorithms for fully automatic, multi-organ segmentation in healthy volunteers. METHODS: The first algorithm is based on classification forests (CFs), the second is based on 3D convolutional neural networks (CNNs) and the third algorithm is based on a multi-atlas (MA) approach...
July 30, 2017: Medical Physics
https://www.readbyqxmd.com/read/28755161/usefulness-of-three-dimensional-image-navigation-system-for-evaluation-of-hepatic-artery-before-living-donor-liver-transplantation-a-case-report
#15
Michinori Matsumoto, Shigeki Wakiyama, Hiroaki Shiba, Yuichi Ishida, Yoshiaki Kita, Katsuhiko Yanaga
BACKGROUND: The evaluation of the hepatic vascular anatomy in living liver donors is increasingly being performed by three-dimensional (3D) computed tomography (CT) angiography. However, details of hepatic artery anatomy obtained by 3D CT angiography are not always superior to those obtained by angiography. Here, we report a case in which the 3D image navigation system helped to detect segment II, III, and IV arteries (A2, A3, and A4, respectively) that individually originated from the proper hepatic artery (PHA); this could not be detected by 3D CT angiography...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28755036/a-pilot-study-for-segmentation-of-pharyngeal-and-sino-nasal-airway-subregions-by-automatic-contour-initialization
#16
Bala Chakravarthy Neelapu, Om Prakash Kharbanda, Viren Sardana, Abhishek Gupta, Srikanth Vasamsetti, Rajiv Balachandran, Shailendra Singh Rana, Harish Kumar Sardana
PURPOSE: The objective of the present study is to put forward a novel automatic segmentation algorithm to segment pharyngeal and sino-nasal airway subregions on 3D CBCT imaging datasets. METHODS: A fully automatic segmentation of sino-nasal and pharyngeal airway subregions was implemented in MATLAB programing environment. The novelty of the algorithm is automatic initialization of contours in upper airway subregions. The algorithm is based on boundary definitions of the human anatomy along with shape constraints with an automatic initialization of contours to develop a complete algorithm which has a potential to enhance utility at clinical level...
July 28, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28753247/take-away-body-parts-an-investigation-into-the-use-of-3d-printed-anatomical-models-in-undergraduate-anatomy-education
#17
Claire F Smith, Nicholas Tollemache, Derek Covill, Malcolm Johnston
Understanding the three-dimensional (3D) nature of the human form is imperative for effective medical practice and the emergence of 3D printing creates numerous opportunities to enhance aspects of medical and healthcare training. A recently deceased, un-embalmed donor was scanned through high-resolution computed tomography. The scan data underwent segmentation and post-processing and a range of 3D-printed anatomical models were produced. A four-stage mixed-methods study was conducted to evaluate the educational value of the models in a medical program...
July 28, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28749375/towards-fast-online-intrafraction-replanning-for-free-breathing-stereotactic-body-radiation-therapy-with-the-mr-linac
#18
Charis Kontaxis, Gijsbert H Bol, Bjorn Stemkens, Markus Glitzner, Fieke M Prins, Linda G W Kerkmeijer, Jan J W Lagendijk, Bas W Raaymakers
The hybrid MRI-radiotherapy machines, like the MR-linac (Elekta AB, Stockholm, Sweden) installed at the UMC Utrecht (Utrecht, The Netherlands), will be able to provide real-time patient imaging during treatment. In order to take advantage of the system's capabilities and enable online adaptive treatments, a new generation of software should be developed, ranging from motion estimation to treatment plan adaptation. In this work we present a proof of principle adaptive pipeline designed for high precision Stereotactic Body Radiation Therapy (SBRT) suitable for sites affected by respiratory motion, like Renal Cell Carcinoma (RCC)...
July 27, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28732595/probabilistic-modeling-of-anatomical-variability-using-a-low-dimensional-parameterization-of-diffeomorphisms
#19
Miaomiao Zhang, William M Wells, Polina Golland
We present an efficient probabilistic model of anatomical variability in a linear space of initial velocities of diffeomorphic transformations and demonstrate its benefits in clinical studies of brain anatomy. To overcome the computational challenges of the high dimensional deformation-based descriptors, we develop a latent variable model for principal geodesic analysis (PGA) based on a low dimensional shape descriptor that effectively captures the intrinsic variability in a population. We define a novel shape prior that explicitly represents principal modes as a multivariate complex Gaussian distribution on the initial velocities in a bandlimited space...
July 8, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28730682/structure-and-development-of-the-subesophageal-zone-of-the-drosophila-brain-i-segmental-architecture-compartmentalization-and-lineage-anatomy
#20
Volker Hartenstein, Jaison J Omoto, Kathy T Ngo, Darren Wong, Philipp A Kuert, Heinrich Reichert, Jennifer K Lovick, Amelia Younossi-Hartenstein
The subesophageal zone (SEZ) of the Drosophila brain houses the circuitry underlying feeding behavior and is involved in many other aspects of sensory processing and locomotor control. Formed by the merging of four neuromeres, the internal architecture of the SEZ can be best understood by identifying segmentally reiterated landmarks emerging in the embryo and larva, and following the gradual changes by which these landmarks become integrated into the mature SEZ during metamorphosis. In previous works, the system of longitudinal fibers (connectives) and transverse axons (commissures) has been utilized as a scaffold that provides internal landmarks for the neuromeres of the larval ventral nerve cord...
July 21, 2017: Journal of Comparative Neurology
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