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https://www.readbyqxmd.com/read/28540752/herpes-zoster-typical-and-atypical-presentations
#1
Roy Rafael Dayan, Roni Peleg
Varicella- zoster virus infection is an intriguing medical entity that involves many medical specialties including infectious diseases, immunology, dermatology, and neurology. It can affect patients from early childhood to old age. Its treatment requires expertise in pain management and psychological support. While varicella is caused by acute viremia, herpes zoster occurs after the dormant viral infection, involving the cranial nerve or sensory root ganglia, is re-activated and spreads orthodromically from the ganglion, via the sensory nerve root, to the innervated target tissue (skin, cornea, auditory canal, etc...
May 25, 2017: Postgraduate Medicine
https://www.readbyqxmd.com/read/28534835/emulsion-based-intradermal-delivery-of-melittin-in-rats
#2
Sang Mi Han, Se Gun Kim, Sok Cheon Pak
Bee venom (BV) has long been used as a traditional medicine. The aim of the present study was to formulate a BV emulsion with good rheological properties for dermal application and investigate the effect of formulation on the permeation of melittin through dermatomed rat skin. A formulated emulsion containing 1% (w/v) BV was prepared. The emulsion was compared with distilled water (DW) and 25% (w/v) N-methyl-2-pyrrolidone (NMP) in DW. Permeation of melittin from aqueous solution through the dermatomed murine skin was evaluated using the Franz diffusion cells...
May 19, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28518084/subcutaneous-trigeminal-nerve-field-stimulation-for-refractory-facial-pain
#3
Martin Jakobs, Sigrid Schuh-Hofer, Andreas Unterberg, Rezvan Ahmadi
Chronic or neuropathic trigeminal facial pain can be challenging to treat. Neurosurgical procedures should be applied when conservative treatment fails. Neuromodulation techniques for chronic facial pain include deep brain stimulation and motor cortex stimulation, which are complex to perform. Subcutaneous nerve field stimulation is certified for chronic back pain and is the least invasive form of neuromodulation. We applied this technique to treat chronic and neuropathic trigeminal pain as an individual therapy concept...
May 10, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28505953/understanding-the-complete-pathophysiology-of-chronic-mild-to-moderate-neck-pain-implications-for-the-inclusion-of-a-comprehensive-sensorimotor-evaluation
#4
Kelly M Cheever, J William Myrer, A Wayne Johnson, Gilbert W Fellingham
BACKGROUND: Inconsistencies in the literature concerning the effect of neck pain have led to a lack of understanding concerning the complete pathophysiology of neck pain. While the effect of neck pain on motor function as measured by active range of motion and isometric neck strength is well documented the effect of neck pain on sensory measures such as tactical acuity and neck reposition error (NRE) remain poorly understood. OBJECTIVE: The purpose of this study was to evaluate a combined sensorimotor evaluation to explore the potential benefits of incorporating both sensory and motor task into a physical evaluation of neck pain suffers to gain an added knowledge of the complete pathophysiology of their health status...
May 5, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28500125/acute-urinary-retention-and-constipation-precipitated-by-herpes-zoster-infection
#5
Eoin MacCraith, Niall F Davis, Kilian Walsh
A 76-year-old man presented to the emergency department complaining of acute urinary retention (AUR) and severe constipation. His recent medical history included 4 days of treatment in the community for gluteal herpes zoster with famciclovir. A transurethral catheter was passed and the patient completed a full course of famciclovir with resolution of constipation. The patient's catheter was successfully removed 3 weeks after his presentation. We report on the clinical presentation and management of an unusual case of AUR and constipation caused by a zoster viral infection of the S2-S4 dermatome...
May 12, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28489642/pupillary-reflex-for-evaluation-of-thoracic-paravertebral-block-a-prospective-observational-feasibility-study
#6
Baptiste Duceau, Mélanie Baubillier, Gaëlle Bouroche, Aline Albi-Feldzer, Christian Jayr
BACKGROUND: Although thoracic paravertebral block (TPVB) is recommended in major breast surgery, there is no gold standard to assess the success of TPVB. Pupillary dilation reflex (PDR) is the variation of the pupillary diameter after a noxious stimulus. The objective was to evaluate the feasibility of recording the PDR to assess analgesia in an anesthetized thoracic dermatome after TPVB. METHODS: This prospective, observational, single-center study included 32 patients requiring breast surgery under general anesthesia and TPVB...
May 4, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28480280/herpes-zoster-and-recurrent-herpes-zoster
#7
Kimiyasu Shiraki, Nozomu Toyama, Tohru Daikoku, Misako Yajima
BACKGROUND: The incidence of recurrent herpes zoster (HZ) and the relationship between initial and recurrent HZ are not clear. METHODS: The Miyazaki Dermatologist Society has surveyed ~5000 patients with HZ annually since 1997. A questionnaire regarding HZ and its recurrence was completed by the dermatologists. RESULTS: A total of 34 877 patients with HZ were registered at 43 clinics between June 2009 and November 2015. Among 16 784 patients seen at 10 of the 43 clinics, 1076 patients (6...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28470404/ex-vivo-human-skin-permeation-of-methylchloroisothiazolinone-mci-and-methylisothiazolinone-mi
#8
Aurélie Berthet, Philipp Spring, David Vernez, Gregory Plateel, Nancy B Hopf
Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are biocides used in many types of products such as cosmetics, paints, and cleaning agents. Skin contact is often encountered when using these products. Although MCI and MI are strong allergens and cause skin irritation, no scientific skin permeation study has been reported except for some unpublished data. Therefore, this study assessed the permeation of MCI and MI both separately and as a mixture through freshly dermatomed human skin (800 µm) in a flow-through diffusion cell system...
May 3, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28460716/does-electrode-placement-influence-tens-induced-antihyperalgesia-in-experimental-inflammatory-pain-model
#9
Maurício L Poderoso Neto, Leonardo Y S Maciel, Kamilla M L Cruz, Valter J Santana Filho, Leonardo R Bonjardim, Josimari M DeSantana
BACKGROUND: Transcutaneous electrical nerve stimulation (TENS) is a treatment commonly used for managing pain; however, the ideal placement of the electrodes is not fully understood. OBJECTIVE: To investigate the best way to apply TENS electrodes in an experimental inflammatory pain model. METHOD: Knee joint inflammation was induced in rats, followed by administration of low-frequency TENS (4Hz) under anesthesia for five days. Animals were randomly allocated to five groups according to electrode placement (n=6, each): dermatome, contralateral, paraspinal, acupoint, and control...
March 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28442806/study-of-clinical-profile-of-herpes-zoster-in-human-immunodeficiency-virus-positive-and-negative-patients-at-a-rural-based-tertiary-care-center-gujarat
#10
Rita V Vora, Gopikrishnan Anjaneyan, Rahul Krishna S Kota, Abhishek P Pilani, Nilofar G Diwan, Nidhi N Patel
BACKGROUND: Herpes zoster usually presents with typically grouped vesicles on erythematous base involving single dermatome with self-limiting nature in immunocompetent individuals while it may present in extensive form involving multiple dermatomes involvement or disseminated form in immunocompromised, especially in human immunodeficiency virus (HIV). AIMS AND OBJECTIVES: The aim of this study was to study the prevalence of HIV in patients of herpes zoster, to compare the clinical presentation of herpes zoster in HIV-infected and noninfected patient...
January 2017: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28436279/treatment-of-painful-radiculopathies-with-capsaicin-8-cutaneous-patch
#11
R Baron, R D Treede, F Birklein, T Cegla, R Freynhagen, M L Heskamp, K U Kern, C Maier, R Rolke, S Seddigh, C Sommer, S Ständer, C Maihöfner
BACKGROUND AND OBJECTIVE: The treatment of neuropathic pain due to low-back (lumbosacral) radiculopathies, a common source of neuropathic pain, is challenging and often requires a multimodal therapeutic approach. The capsaicin 8% patch is the first topical analgesic licensed for peripheral neuropathic pain. To evaluate this treatment, a subset of patients with painful radiculopathy (lumbar and cervical, including ventral and dorsal rami) enrolled into the multicenter, non-interventional QUEPP study (Qutenza (2) - safety and effectiveness in peripheral neuropathic pain) was analyzed...
May 4, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28435923/bone-bridge-formation-across-the-neuroforamen-14-years-after-instrumented-fusion-for-isthmic-spondylolisthesis-a-case-report
#12
Joel Louis Lim, Kimberly-Anne Tan, Hwee Weng Dennis Hey
This case report describes the first case of a bone bridge formation across the left L5/S1 neuroforamen after instrumented posterolateral fusion for L5/S1 isthmic spondylolisthesis. Our patient was a 70-year-old lady who had grade 2, L5/S1 isthmic spondylolisthesis and bilateral S1 nerve root compression. She suffered from mechanical low back pain and neurogenic claudication, with radicular pain over both S1 dermatomes. She underwent in-situ, instrumented, posterolateral fusion and was asymptomatic for more than 13 years before developing progressive onset of left radicular pain over the L5 dermatome...
March 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28431427/total-spinal-anesthesia-failure-have-you-assessed-the-sensory-anesthesia-in-sacral-dermatomes
#13
Ronaldo Rodrigo de Sá Oliveira, Marília Pinheiro Módolo, Glênio Bitencourt Mizubuti, Anthony M H Ho, Guilherme Antonio Moreira de Barros, Leopoldo Muniz da Silva, Leandro Gobbo Braz, Norma Sueli Pinheiro Módolo, Andrew G Day, Rachel Phelan, Lais Helena Navarro E Lima, Eliana Marisa Ganem
Intrathecal local anesthetic maldistribution is a well-known cause of spinal anesthesia failure (SAF). This could potentially result in sensory blockade restricted to the sacral dermatomes. We sought to determine the overall incidence of SAF and the role of sacral dermatomes in differentiating between total and partial failures. Of the 3111 spinals prospectively examined, 194 (6.2%) were classified as failures. Of the 72 presumed total failures based on the initial assessment, evaluation of the sacral dermatomes revealed sensory blockade in 32 (44%; 95% confidence interval, 32...
May 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28427688/pruritus-may-be-a-common-symptom-related-to-neuromyelitis-optica-spectrum-disorders
#14
Zhiyong He, Ming Ren, Xiaofeng Wang, Qifeng Guo, Xiaokun Qi
BACKGROUND: To evaluate pruritus in patients with neuromyelitis optica spectrum disorders (NMOSD) and to characterize the relationship between pruritus and lesions of NMOSD. METHODS: 61 patients with NMOSD were included in the study and their medical records were reviewed for pruritus, neurological symptoms and magnetic resonance imaging (MRI) images. We focused on the patients' history of pruritus, especially the severity, duration, region, and the relationship of pruritus with other symptoms of NMOSD...
April 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28416562/henry-head-herpes-zoster-and-the-graphic-development-of-his-scheme-of-the-dermatomes-in-man
#15
G D Schott
No abstract text is available yet for this article.
April 17, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28413738/high-energy-trauma-precipitating-intramedullary-cavernous-malformation-hemorrhage-a-possible-underreported-mechanism
#16
Pedro Aguilar-Salinas, Douglas Gonsales, Leonardo B Brasiliense, Eric Sauvageau, Ricardo A Hanel
Cavernous malformations are uncommon vascular lesions with an estimated prevalence of 0.5% in the general population. Intramedullary cavernous malformations (ICM) represent a rare subset of lesions, which account for approximately 5% of all cavernous malformations. The annual risk of hemorrhage in ICMs has been reported to range from 1.4 to 6.8%. Most patients are diagnosed with neurological dysfunction secondary to ICM hemorrhage and little is known about the inciting events that lead to hemorrhage. A few studies have suggested that minor and major trauma or even intense exertion may increase the risk of hemorrhage...
March 13, 2017: Curēus
https://www.readbyqxmd.com/read/28413557/c2-primary-leiomyoma-in-an-immunocompetent-woman-a-case-report-and-review-of-literature
#17
Mohana Rao Patibandla, Madhukar T Nayak, A K Purohit, Megha Uppin, Sundaram Challa, Gokul Chowdary Addagada, Manisha Nukavarapu
Clinical case report and review of the literature. This is the first case of primary leiomyoma in an immunocompetent woman without previous history of uterine leiomyoma being reported in the literature to the best of our knowledge. Leiomyoma, a type of smooth muscle cell tumor, involving the vertebra is extremely rare. There were very few primary leiomyoma in patients with AIDS or in the immune-suppressed patients. This 48-year-old female came with H/o neck pain, weakness and bladder retention. On examination, tone increased in all four limbs, power on the right side of the limbs 4/5, power on the left upper limb 0/5, lower limb 3/5, left plantar was up going, decreased sensation over the left second cervical vertebra (C2) dermatome and all modalities decreased below C2...
January 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28410481/leg-symptoms-associated-with-sacroiliac-joint-disorder-and-related-pain
#18
Eiichi Murakami, Toshimi Aizawa, Daisuke Kurosawa, Kyoko Noguchi
OBJECTIVE: The symptoms of sacroiliac joint (SIJ) disorders are usually detected in the buttock and groin, and occasionally referred to the thigh and leg. However, lumbar disorders also cause symptoms in these same body regions. The presence of a characteristic, symptomatic pattern in the legs would be useful for diagnosing SIJ disorders. This study aimed to identify specific leg symptoms in patients with SIJ pain originating from the posterior sacroiliac ligament and determine the rate of occurrence of these symptoms...
June 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28386739/analgesia-and-side-effects-of-the-addition-of-10-or-20%C3%A2-%C3%A2%C2%B5g-fentanyl-to-articaine-in-spinal-anesthesia-for-knee-arthroscopy-a-randomized-and-observer-blinded-study
#19
Paula Stenman, Merja Salonen, Pekka Tarkkila, Per Rosenberg
OBJECTIVES: Articaine, a popular and rapidly acting local anesthetic in dentistry, has been also found to be beneficial in ambulatory spinal anesthesia. Analgesia in the intraoperative and immediate postoperative period may be further improved by adding fentanyl to the local anesthetic solution for spinal anesthesia. The aim was to evaluate dose-dependency of analgesia and side effects associated with intrathecal fentanyl additive to articaine for spinal anesthesia in knee arthroscopy patients...
April 6, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28365432/long-term-outcome-of-brachial-plexus-re-implantation-after-complete-brachial-plexus-avulsion-injury
#20
C Kachramanoglou, T Carlstedt, M Koltzenburg, D Choi
BACKGROUND: Complete brachial plexus avulsion injury is a severe disabling injury due to traction to the brachial plexus. Brachial plexus re-implantation is an emerging surgical technique for the management of complete brachial plexus avulsion injury. OBJECTIVE: We assessed the functional recovery in 15 patients who have undergone brachial plexus re-implantation surgery after complete brachial plexus avulsion injury with clinical examination and electrophysiological testing METHODS: We included all patients that underwent brachial plexus re-implantation in our institution between 1997 and 2010...
March 29, 2017: World Neurosurgery
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