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https://www.readbyqxmd.com/read/27917700/posterior-reversible-encephalopathy-syndrome-following-elevated-mean-arterial-pressures-for-cervical-spinal-cord-injury
#1
Jeffrey H Zimering, Addisu Mesfin
BACKGROUND: Increasing the mean arterial pressure (MAP) is an accepted treatment modality to minimize the risk for irreversible neurologic damage secondary to spinal cord ischemia. Posterior reversible encephalopathy syndrome (PRES) is a rare complication occurring after transplantation surgery, in persons having an autoimmune disorder or after abrupt increases in blood pressure of various etiologies. STUDY DESIGN: Case report. METHODS: Retrospective evaluation of medical records...
December 5, 2016: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/27904277/herpes-zoster-duplex-unilateralis-two-cases-and-brief-literature-review
#2
Jee Hee Son, Bo Young Chung, Hye One Kim, Hee Jin Cho, Chun Wook Park
Cases involving dermatomal herpes zoster in two or more locations are rare, especially in immunocompetent patients. When two noncontiguous dermatomes are involved, if affected unilaterally, it is called herpes zoster duplex unilateralis; if bilaterally, bilateralis. Here, we report two cases of herpes zoster duplex unilateralis. A 66-year-old man presented with painful erythematous grouped vesicles on his left scalp, forehead, trunk, and back (left [Lt.] V1, Lt. T8). Histologic findings were consistent with herpetic infection...
December 2016: Annals of Dermatology
https://www.readbyqxmd.com/read/27904265/a-study-of-intravenous-administration-of-vitamin-c-in-the-treatment-of-acute-herpetic-pain-and-postherpetic-neuralgia
#3
Min Sung Kim, Dong Jin Kim, Chan Ho Na, Bong Seok Shin
BACKGROUND: Although there are several available management strategies for treatment of both acute pain of herpes zoster (HZ) and postherpetic neuralgia (PHN), it is difficult to treat them adequately. OBJECTIVE: The aim of this study was to evaluate the efficacy of intravenously administrated vitamin C on acute pain and its preventive effects on PHN in patients with HZ. METHODS: Between September 2011 and May 2013 eighty-seven patients who were admitted for HZ were assessed according to age, sex, underlying diseases, duration of pain and skin lesion, dermatomal distribution, and PHN...
December 2016: Annals of Dermatology
https://www.readbyqxmd.com/read/27903340/-the-clinical-application-of-lumbar-plexus-the-first-posterior-sacral-foramina-block-for-hip-arthroplasty-in-elderly-patients
#4
J Li, X J Ke, Y Liu, K Chen, M B Chen, W Mei
Objective: To evaluate the clinical efficacy of lumbar plexus-the first posterior sacral foramina block as an anesthesia technique for hip arthroplasty in elderly patients. Methods: Forty-four patients, aged 60-91 years, weighing 37-100 kg, American Society of Anesthesiologists (ASA) Ⅰ-Ⅲ, underwent elective hip arthroplasty in Tongji Hospital from February 2015 to January 2016.All patients received lumbar plexus and the first posterior sacral foramina block.The first posterior sacral foramina puncture point of 23 cases were located by traditional positioning method, the others were orientated via ultrasonic method...
November 22, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27900771/laparoscopic-guided-psoas-blockade-as-a-novel-analgesic-method-during-inguinal-herniorrhaphy-a-clinical-trial
#5
T F Tammam, A F Salama
BACKGROUND: Under laparoscopic guidance, block of ilioinguinal, iliohypogastric, and genitofemoral nerves can be possible with anesthetic injection in the plane between psoas major and the fasciae covering its anterior aspects [laparoscopic-assisted psoas (LAP) blockade]. This observer-blinded trial aimed to compare the opioid-sparing effect of LAP block with transversus abdominis plane (TAP) block after laparoscopic inguinal herniorrhaphy. METHODS: Forty-five male patients were randomly assigned to receive LAP block, group LAP (n = 23), or ultrasound-guided TAP block, group TAP (n = 22)...
November 30, 2016: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/27897183/sensory-thresholds-at-different-sites-of-the-foot-a-valuable-reference-for-neurologic-examinations
#6
J-W Zhang, Q Wang, X-F Wang, M-M Gao, X-P Yun, H-F Wu, Y Hong
STUDY DESIGN: Prospective healthy volunteer study for sensory thresholds. OBJECTIVES: The aim of this study was to test sensory thresholds at different sites of the foot to provide a reference for diagnosis and neurologic classification. SETTING: A university hospital for the research and clinical practice of rehabilitation. METHODS: Thirty healthy volunteers were recruited, and quantitative sensory testing was performed on three sites of the foot (medial malleolus (for the L4 dermatome), dorsum of the foot at the third metatarsal phalangeal joint (for the L5 dermatome) and lateral heel (for the S1 dermatome))...
November 29, 2016: Spinal Cord
https://www.readbyqxmd.com/read/27896665/ultrasound-guided-thoracic-paravertebral-block-by-the-paralaminar-in-plane-approach-using-a-microconvex-array-transducer-methodological-utility-based-on-anatomical-structures
#7
Yasuko Taketa, Taro Fujitani, Yumi Irisawa, Satoko Sudo, Kazushi Takaishi
OBJECTIVE: We evaluated the analgesic feasibility of paralaminar in-plane (PL) approach for ultrasound-guided thoracic paravertebral block (USG-TPVB). As the needle trajectory was expected to be closely affected by the distance from the skin to the lamina-transverse process junction (LTPJ), we examined the correlativity between them on computed tomography (CT) or ultrasonography. METHODS: Thirty-two patients undergoing thoracotomy were recruited. We measured the distances between the skin and LTPJ using preoperative CT (S-L) and procedural ultrasonography (US-L)...
November 28, 2016: Journal of Anesthesia
https://www.readbyqxmd.com/read/27891579/unexpected-motor-weakness-following-quadratus-lumborum-block-for-gynaecological-laparoscopy
#8
M Wikner
Quadratus lumborum block has recently been described as an effective and long-lasting analgesic strategy for various abdominal operations, including gynaecological laparoscopy. Despite evidence that the analgesic effect is mediated by indirect paravertebral block and that local anaesthetic spreads to the lumbar paravertebral space, there have been no reports to date of lower limb motor weakness. We present a patient with unilateral hip flexion and knee extension weakness leading to unplanned overnight admission following lateral quadratus lumborum block with 20 ml levobupivacaine 0...
November 28, 2016: Anaesthesia
https://www.readbyqxmd.com/read/27890168/incidence-and-prevention-of-herpes-zoster-reactivation-in-patients-with-autoimmune-diseases
#9
REVIEW
Eliza F Chakravarty
Herpes zoster is the reactivation of latent varicella zoster virus usually occurring decades after initial exposure, and manifesting as a painful vesicular rash occurring along one or more dermatomes. Zoster incidence increases with age as cell mediated immunity against latent virus wanes. Epidemiological evidence suggests that individuals with underlying rheumatic diseases are at increased risk for zoster. It remains unclear whether this is due to immunosuppressive medications or from immune dysregulation of the underlying disease...
February 2017: Rheumatic Diseases Clinics of North America
https://www.readbyqxmd.com/read/27885288/correlation-between-clinical-features-and-magnetic-resonance-imaging-findings-in-lumbar-disc-prolapse
#10
S S Thapa, R B Lakhey, P Sharma, R K Pokhrel
BACKGROUND: Magnetic resonance imaging is routinely done for diagnosis of lumbar disc prolapse. Many abnormalities of disc are observed even in asymptomatic patient.This study was conducted tocorrelate these abnormalities observed on Magnetic resonance imaging and clinical features of lumbar disc prolapse. METHODS: A This prospective analytical study includes 57 cases of lumbar disc prolapse presenting to Department of Orthopedics, Tribhuvan University Teaching Hospital from March 2011 to August 2012...
May 2016: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/27870737/the-influence-of-body-mass-index-on-sensorimotor-block-and-vasopressor-requirement-during-spinal-anesthesia-for-elective-cesarean-delivery
#11
T C Ngaka, J F Coetzee, R A Dyer
BACKGROUND: It has been suggested that the dose requirement for spinal anesthesia (SA) is lower in obese patients for cesarean delivery (CD). In this prospective, observational, noninferiority study, we tested the hypothesis that obesity would not have a clinically important effect on vasopressor requirements or block height. METHODS: Two groups of 25 parturients, group O (body mass index [BMI] >40 kg/m) and group N (BMI <32 kg/m) requiring elective CD were recruited...
December 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27862251/anatomic-variability-of-the-lateral-femoral-cutaneous-nerve-value-of-3t-mri-in-identifying-anomaly-for-surgical-intervention
#12
Jan Fritz, Denniz Zolnoun, A Lee Dellon
The anatomic variability of the lateral femoral cutaneous nerve (LFC) creates diagnostic as well as therapeutic problems. A case is reported in which a woman with complaints of pain in the anterior and lateral thigh was referred for evaluation. Symptoms arose after an abdominal hysterectomy. Her symptoms were the territory of the LFC and not of the L2/L3 dermatome. She had a Tinel sign that was positive for the LFC skin territory, but this was located over the anterior superior iliac spine (ASIS), instead of medial to it...
November 11, 2016: Microsurgery
https://www.readbyqxmd.com/read/27855658/cytomegalovirus-associated-encephalomyelitis-in-an-immunocompetent-adult-a-two-stage-attack-of-direct-viral-and-delayed-immune-mediated-invasions-case-report
#13
Kensuke Daida, Yuta Ishiguro, Hiroto Eguchi, Yutaka Machida, Nobutaka Hattori, Hideto Miwa
BACKGROUND: It is clinically rare to find cytomegalovirus (CMV)-associated encephalomyelitis in immunocompetent adults. Here, we present the case of an adult patient who developed acute transverse myelitis that was followed by immune-mediated disseminated encephalomyelitis. CASE PRESENTATION: A 38-year-old man developed acute paraplegia with paresthesia below the level of the T7-8 dermatome. Both brain and spinal cord MRIs performed at admission appeared normal...
November 17, 2016: BMC Neurology
https://www.readbyqxmd.com/read/27834055/biopharmaceutical-assessment-and-irritation-potential-of-microemulsions-and-conventional-systems-containing-oil-from-syagrus-cearensis-for-topical-delivery-of-amphotericin-b-using-alternative-methods
#14
Giovana D Sousa, Juliana Kishishita, Kátia A S Aquino, Octávio A F Presgrave, Leila B Leal, Davi P Santana
The aim of this study was to compare the biopharmaceutical characteristics and irritation potentials of microemulsions (MEs) and conventional systems (CSs) containing oil from Syagrus cearensis for topical delivery of Amphotericin B (AmB). Pseudo-ternary phase diagrams were constructed using a water titration method to develop the MEs, and the CSs were prepared according to the classical technique of phase inversion. In the skin permeation and retention study, dermatomed pig skin without stratum corneum was used as an alternative disturbed skin model...
November 10, 2016: AAPS PharmSciTech
https://www.readbyqxmd.com/read/27829533/dermatomal-sensory-manifestations-in-opalski-syndrome
#15
Tomoya Kon, Yukihisa Funamizu, Tatsuya Ueno, Rie Haga, Haruo Nishijima, Akira Arai, Chieko Suzuki, Jinichi Nunomura, Masayuki Baba, Masahiko Tomiyama
A 31-year-old Japanese woman presented with sudden-onset unstable gait followed by nuchal pain. A neurological examination revealed right-sided limb weakness and decreased pain and thermal sensation on the left side below the level of the L1 dermatome. A lower lateral medullary infarction with ipsilateral hemiplegia, known as Opalski syndrome, caused by spontaneous vertebral artery dissection was diagnosed by magnetic resonance imaging. The spinothalamic tract in the medulla oblongata has a topographic arrangement of sensory fibers, and the dermatomal sensory deficit in this case can be explained in relation to that...
November 7, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27818244/the-effect-of-pulse-duration-power-and-energy-of-fractional-er-yag-laser-for-transdermal-delivery-of-differently-sized-fitc-dextrans
#16
Barbara Zorec, Dejan Škrabelj, Marko Marinček, Damijan Miklavčič, Nataša Pavšelj
We studied fractional Er:YAG laser to enhance transdermal drug delivery of compounds possessing different molecular weights: FITC-dextrans (or FD) with average molecular weights of 4, 10 and 20kDa. Vertical glass Franz diffusion cells were used to study molecular transport through dermatomed porcine skin and histological analysis of laser-treated skin was performed after treatment with different laser pulse protocols. We were comparing different pulse durations at constant or varying pulse energies. We found that the energy of the delivered pulses mostly dictates the size/depth of laser-created microchannels, while the duration of the pulses dictates the extent of thermally altered tissue...
November 3, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27803655/sustained-effects-of-acupuncture-stimulation-investigated-with-centrality-mapping-analysis
#17
Xiangyu Long, Wenjing Huang, Vitaly Napadow, Fanrong Liang, Burkhard Pleger, Arno Villringer, Claudia M Witt, Till Nierhaus, Daniel Pach
: Acupuncture can have instant and sustained effects, however, its mechanisms of action are still unclear. Here, we investigated the sustained effect of acupuncture by evaluating centrality changes in resting-state functional magnetic resonance imaging after manually stimulating the acupuncture point ST36 at the lower leg or two control point locations (CP1 same dermatome, CP2 different dermatome). Data from a previously published experiment evaluating instant BOLD effects and S2-seed-based resting state connectivity was re-analyzed using eigenvector centrality mapping and degree centrality mapping...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27789772/blunted-increases-in-skin-sympathetic-nerve-activity-are-related-to-attenuated-reflex-vasodilation-in-aged-human-skin
#18
Anna E Stanhewicz, Jody L Greaney, Lacy M Alexander, W Larry Kenney
Reflex cutaneous vasodilation in response to passive heating is attenuated in human aging. This diminished response is mediated, in part, by age-associated reductions in endothelial function; however, the contribution of altered skin sympathetic nervous system activity (SSNA) is unknown. We hypothesized that 1) healthy older adults would demonstrate blunted SSNA responses to increased core temperature compared to young adults, and 2) the decreased SSNA response would be associated with attenuated cutaneous vasodilation...
October 27, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/27779562/implantation-of-bone-anchored-hearing-devices-through-a-minimal-skin-punch-incision-versus-the-epidermal-flap-technique
#19
Thibaud Dumon, Inge Wegner, Neil Sperling, Wilko Grolman
OBJECTIVE: To compare the minimal skin punch incision without additional skin incision or soft tissue reduction with the epidermal flap technique and soft tissue reduction, for the implantation of percutaneous bone-anchored hearing devices. STUDY DESIGN: Prospective cohort study. SETTING: Tertiary care referral center. SUBJECTS AND METHODS: Two hundred seventeen patients underwent 220 implantations. Sixty five cases underwent implantation by means of a skin punch resection without soft tissue reduction (punch group) and 155 cases underwent epidermal flap and soft tissue reduction (dermatome group)...
October 21, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27772619/%C3%AE-herpes-virus-infections-among-renal-transplant-recipients
#20
REVIEW
Cybele Lara Abad, Raymund R Razonable
The α herpes viruses HSV-1, HSV-2, and VZV often reactivate in the setting of immune suppression after solid organ transplantation. Oral or genital mucocutaneous disease is the most common clinical manifestation of HSV disease while VZV manifests as varicella (or chickenpox) or reactivation herpes zoster, characterized by a diffuse rash, or a painful unilateral vesicular eruption in a dermatomal distribution, respectively. The diagnosis of HSV and VZV is primarily based on history and clinical presentation, although diagnostic tests may be necessary for atypical presentations of disease...
September 2016: Seminars in Nephrology
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