Zihan Yin, Ziqi Wang, Yaqin Li, Jun Zhou, Zhenghong Chen, Manze Xia, Xinyue Zhang, Jiajing Wu, Ling Zhao, Fanrong Liang
BACKGROUND: Acupuncture effectively improves cognitive function in Alzheimer's disease (AD). Many neuroimaging studies have found significant brain alterations after acupuncture treatment of AD, but the underlying central modulation mechanism is unclear. OBJECTIVE: This review aims to provide neuroimaging evidence to understand the central mechanisms of acupuncture in patients with AD. METHODS: Relevant neuroimaging studies about acupuncture for AD were retrieved from eight English and Chinese medicine databases (PubMed, Embase, Cochrane Library, Web of Science, SinoMed, CNKI, WF, VIP) and other resources from inception of databases until June 1, 2022, and their methodological quality was assessed using RoB 2...
February 23, 2023: BMC complementary medicine and therapies