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fMRI acupuncture

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https://www.readbyqxmd.com/read/27812501/repeated-acupuncture-treatments-modulate-amygdala-resting-state-functional-connectivity-of-depressive-patients
#1
Xiaoyun Wang, Zengjian Wang, Jian Liu, Jun Chen, Xian Liu, Guangning Nie, Joon-Seok Byun, Yilin Liang, Joel Park, Ruiwang Huang, Ming Liu, Bo Liu, Jian Kong
As a widely-applied alternative therapy, acupuncture is gaining popularity in Western society. One challenge that remains, however, is incorporating it into mainstream medicine. One solution is to combine acupuncture with other conventional, mainstream treatments. In this study, we investigated the combination effect of acupuncture and the antidepressant fluoxetine, as well as its underlying mechanism using resting state functional connectivity (rsFC) in patients with major depressive disorders. Forty-six female depressed patients were randomized into a verum acupuncture plus fluoxetine or a sham acupuncture plus fluoxetine group for eight weeks...
2016: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27693978/acupuncture-treatment-modulates-the-corticostriatal-reward-circuitry-in-major-depressive-disorder
#2
Zengjian Wang, Xiaoyun Wang, Jian Liu, Jun Chen, Xian Liu, Guangning Nie, Kristen Jorgenson, Ki Cheul Sohn, Ruiwang Huang, Ming Liu, Bo Liu, Jian Kong
Major depressive disorder (MDD) is a common disorder with a high prevalence and significant social and economic impacts. Nevertheless, the treatment of MDD is far from satisfactory. Acupuncture treatment has emerged as a promising method for treating MDD. However, the neural mechanism by which acupuncture reduces depressive symptoms is not fully understood. Studies have shown that the corticostriatal reward circuitry is associated with the pathophysiology of MDD; thus, we investigated the corticostriatal resting-state functional connectivity (rsFC) before and after real and sham acupuncture treatments combined with the antidepressant fluoxetine...
January 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/27688791/acupuncture-decreases-blood-pressure-related-to-hypothalamus-functional-connectivity-with-frontal-lobe-cerebellum-and-insula-a-study-of-instantaneous-and-short-term-acupuncture-treatment-in-essential-hypertension
#3
Yu Zheng, Jiping Zhang, Yanjie Wang, Yuying Wang, Yujun Lan, Shanshan Qu, Chunzhi Tang, Yong Huang
The therapeutic effects of acupuncture in decreasing blood pressure are ambiguous and underlying acupuncture in hypertension treatment has not been investigated. Our objective was to observe the change of quality of life and compare the differences in brain functional connectivity by investigating instantaneous and short-term acupuncture treatment in essential hypertension patients. A total of 30 patients were randomly divided into the LR3 group and sham acupoint group. Subjects received resting-state fMRI among preacupuncture, postinstantaneous, and short-term acupuncture treatment in two groups...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27567596/the-brain-effects-of-laser-acupuncture-at-thirteen-ghost-acupoints-in-healthy-individuals-a-resting-state-functional-mri-investigation
#4
Jian Lv, Changzheng Shi, Yanjia Deng, Wutao Lou, Jing Hu, Lin Shi, Liangping Luo, Defeng Wang
Acupuncture at thirteen ghost acupoints (TGA) was an effective treatment of neuropsychological disorders. However, the underlying neurological mechanisms of acupuncture at the TGA have not been revealed by modern scientific technologies. As laser acupuncture emerges with the painless and noninvasive advantages and the functional magnetic resonance imaging (fMRI) allows us to investigate the activation of the brain in vivo, we performed the preliminary study to investigate the relation to brain effects of acupuncture at TGA based on resting-state fMRI (rs-fMRI)...
December 2016: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/27562659/difficulties-choosing-control-points-in-acupuncture-research-response-commentary-differential-cerebral-response-measured-with-both-an-eeg-and-fmri-to-somatosensory-stimulation-of-a-single-acupuncture-point-vs-two-non-acupuncture-points
#5
COMMENT
Till Nierhaus, Daniel Pach, Wenjing Huang, Xiangyu Long, Vitaly Napadow, Stephanie Roll, Fanrong Liang, Burkhard Pleger, Arno Villringer, Claudia M Witt
No abstract text is available yet for this article.
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27555221/does-acupuncture-alter-pain-related-functional-connectivity-of-the-central-nervous-system-a-systematic-review
#6
REVIEW
María Villarreal Santiago, Steve Tumilty, Aleksandra Mącznik, Ramakrishnan Mani
Acupuncture has been studied for several decades to establish evidence-based clinical practice. This systematic review aims to evaluate evidence for the effectiveness of acupuncture in influencing the functional connectivity of the central nervous system in patients with musculoskeletal pain. A systematic search of the literature was conducted to identify studies in which the central response of acupuncture in patients with musculoskeletal pain was evaluated by neuroimaging techniques. Databases searched were AMED, CINAHL, Cochrane Library, EMBASE, MEDLINE, PEDro, Pubmed, SCOPUS, SPORTDiscuss, and Web of Science...
August 2016: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/27438091/changes-in-regional-brain-homogeneity-induced-by-electro-acupuncture-stimulation-at-the-baihui-acupoint-in-healthy-subjects-a-functional-magnetic-resonance-imaging-study
#7
Demao Deng, Gaoxiong Duan, Hai Liao, Yanfei Liu, Geliang Wang, Huimei Liu, Lijun Tang, Yong Pang, Jien Tao, Xin He, Wenzhao Yuan, Peng Liu
INTRODUCTION: According to the Traditional Chinese Medicine theory of acupuncture, Baihui (GV20) is applied to treat neurological and psychiatric disorders. However, the relationships between neural responses and GV20 remain unknown. Thus, the main aim of this study was to examine the brain responses induced by electro-acupuncture stimulation (EAS) at GV20. MATERIALS AND METHODS: Functional magnetic resonance imaging (fMRI) was performed in 33 healthy subjects. Based on the non-repeated event-related (NRER) paradigm, group differences were examined between GV20 and a sham acupoint using the regional homogeneity (ReHo) method...
October 2016: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/27386646/-amplitude-changes-of-low-frequency-fluctuation-in-brain-spontaneous-nervous-activities-induced-by-needling-at-hand-taiyin-lung-channel
#8
You-long Zhou, Cheng-guo Su, Shou-fang Liu, Xiang-yu Jin, Yan-li Duan, Xiao-yan Chen, Shu-hua Zhao, Quan-liang Wang, Chang-lin Dang
OBJECTIVE: To observe amplitude changes of low frequency fluctuation in brain spontaneous nervous activities induced by needling at Hand Taiyin Lung Channel, and to preliminarily explore the possible brain function network of Hand Taiyin Lung Channel. METHODS: By using functional magnetic resonance imaging (fMRI), 16 healthy volunteers underwent resting-state scanning (R1) and scanning with retained acupuncture at Hand Taiyin Lung Channel (acupuncture, AP). Data of fMRI collected were statistically calculated using amplitude of low frequency fluctuations (ALFF)...
May 2016: Chinese Journal of Integrated Traditional and Western Medicine
https://www.readbyqxmd.com/read/27242492/modulation-of-the-default-mode-network-in-first-episode-drug-na%C3%A3-ve-major-depressive-disorder-via-acupuncture-at-baihui-gv20-acupoint
#9
Demao Deng, Hai Liao, Gaoxiong Duan, Yanfei Liu, Qianchao He, Huimei Liu, Lijun Tang, Yong Pang, Jien Tao
BACKGROUND: Previous neuroimaging studies have revealed that acupuncture modulates the default mode network (DMN) in healthy subjects and patients with certain disorder. However, few studies have been performed to investigate whether or not acupuncture might modulate the DMN in patients with major depressive disorder (MDD). Thereby, the aim of the present study was to assess alterations of the DMN induced by acupuncture stimulation in patients with first-episode, drug-naïve MDD. MATERIALS AND METHODS: Twenty nine patients with first-episode, drug-naïve MDD and 29 healthy subjects were enrolled in this study...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27193838/gender-differences-in-the-neural-response-to-acupuncture-clinical-implications
#10
Sujung Yeo, Bruce Rosen, Peggy Bosch, Maurits van den Noort, Sabina Lim
OBJECTIVE: To examine gender differences and similarities in the psychophysical and brain responses to acupuncture at GB34, a point that is frequently used to treat motor function issues in Traditional Chinese Medicine. METHODS: Functional MRI (fMRI) was used to measure brain activation in response to acupuncture at GB34 (on the right) in 19 healthy participants (9 male, 10 female). De qi sensations were rated to measure their psychophysical responses. RESULTS: Overall de qi scores did not differ by gender, although females reported greater intensity of aching (p=0...
May 18, 2016: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/27062952/a-study-of-the-brain-functional-network-of-deqi-via-acupuncturing-stimulation-at-bl40-by-rs-fmri
#11
Yu Shi, Shanshan Zhang, Qiang Li, Ziping Liu, Shigui Guo, Jiangming Yang, Wen Wu
OBJECTIVE: Acupuncture is a therapeutic treatment defined as the insertion of needles into the body at specific points (i.e., acupoints). The acupuncture sensation of Deqi is an important component of acupuncture, but the functional brain responses of Deqi have not been entirely supported by the results of functional magnetic resonance imaging (fMRI) studies. The aims of this study were to test the conditions that would generate a Deqi sensation and to investigate the effect of Deqi and the response of acupuncture at different depths and intensities on brain fMRI blood oxygen level-dependent (BOLD) signals...
April 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27039086/effect-of-acupuncture-and-its-influence-on-cerebral-activity-in-functional-dyspepsia-patients-study-protocol-for-a-randomized-controlled-trial
#12
Seok-Jae Ko, Kyungmo Park, Jieun Kim, Minji Kim, Joo-Hee Kim, Jeungchan Lee, Abdalla Z Mohamed, Inkwon Yeo, Jinsung Kim, Sun-Mi Choi, Honggeol Kim, Jae-Woo Park, Jun-Hwan Lee
BACKGROUND: Functional dyspepsia (FD) is a prevalent gastric disorder that is difficult to manage due to lack of satisfactory treatments. Acupuncture has been studied with regard to the rising need for treating FD, but the mechanism verifying its efficacy has not yet been fully revealed. The aim of this study is to explore the efficacy and mechanism of acupuncture for FD compared with a sham group. METHODS/DESIGN: We describe a proposal for a randomized, assessor-blind, sham-controlled trial with 70 eligible participants who will be randomly allocated either into an acupuncture or a sham group...
2016: Trials
https://www.readbyqxmd.com/read/27002910/cerebral-activation-effects-of-acupuncture-using-zusanli-st36-and-yanglingquan-gb34-points-based-on-regional-homogeneity-indices-a-resting-state-fmri-study
#13
Liansheng Liu, Yuefeng Wu, Jiayi Zheng, Xinsheng Lai, Daohui Zeng, Hengguo Li, Changzheng Shi, Minjie Yang, Changhong Liang
OBJECTIVE: This study aimed to observe the cerebral activation effects of acupuncturing the Zusanli (ST36) plusYanglingquan (GB34) points in young healthy volunteers based on Regional Homogeneity (ReHo) indices. METHODS: Ten healthy volunteers were enrolled, including 4 males and 6 females between the ages 20 and 34 years with a median age of 23 years. Magnetic resonance imaging (GE Signa HDxt 3.0T) was performed in four groups: Before acupuncture (Control Group), after acupuncture at Zusanli (ST36 Group), after acupuncture at Yanglingquan (GB34 Group) and after acupuncture at both Zusanli and Yanglingquan (Compatibility Group)...
2016: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/26964172/-midnight-noon-ebb-flow-acupuncture-at-stomach-meridian-of-foot-yangming-a-fmri-study
#14
Ri Chen
The status change of brain functional region of functional magnetic resonance imaging (fMRI) of midnight-noon ebb-flow acupuncture method at stomach meridian was explored. Ten healthy volunteers were recruited. With identical sequence of magnetic resonance scans, fMRI data was collected respectively in the timely acupoint group, untimely acupoint group and timely non-acupoint group. Volunteers in the timely acupoint group were treated at Zusanli (ST 36) and Chongyang (ST 42) between 7:02:53 A.M. to 9:02:52 A...
December 2015: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/26924978/commentary-differential-cerebral-response-to-somatosensory-stimulation-of-an-acupuncture-point-vs-two-non-acupuncture-points-measured-with-eeg-and-fmri
#15
https://www.readbyqxmd.com/read/26902192/-changes-of-brain-pain-center-and-default-mode-network-an-electro-acupuncture-in-weizhong-and-dachangshu-acupoints-a-task-fmri-study
#16
S Zhou, H X Cao, L C Yu, Y J Jin, R H Jia, Y R Wen, X F Chen
OBJECTIVE: To investigate the functional brain pain center and default mode network response to electro acupuncture stimulate in weizhong acupoints(BL40) and dachangshu acupoints(BL25). METHODS: During January to February 2015, volunteers were enrolled in this study from the staff and student interns of Gansu Province Traditional Chinese Medicine Hospital. A total of 20 healthy, right-handed subjects, male 9, female 11, age (23±3) years, participated in this study...
February 23, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/26889189/acupuncture-for-ischemic-stroke-cerebellar-activation-may-be-a-central-mechanism-following-deqi
#17
Miao-Keng Li, Yu-Jie Li, Gui-Feng Zhang, Jun-Qi Chen, Ji-Ping Zhang, Ji Qi, Yong Huang, Xin-Sheng Lai, Chun-Zhi Tang
The needling sensation of Deqi during acupuncture is a key factor of influencing acupuncture outcome. Recent studies have mainly focused on the brain function effects of Deqi in a physiological state. Functional magnetic resonance imaging (fMRI) on the effects of acupuncture at Waiguan (SJ5) in pathological and physiological states is controversial. In this study, 12 patients with ischemic stroke received acupuncture at Waiguan (SJ5) and simultaneously underwent fMRI scanning of the brain, with imaging data of the activated areas obtained...
December 2015: Neural Regeneration Research
https://www.readbyqxmd.com/read/26839078/altered-periaqueductal-gray-resting-state-functional-connectivity-in-migraine-and-the-modulation-effect-of-treatment
#18
Zhengjie Li, Mailan Liu, Lei Lan, Fang Zeng, Nikos Makris, Yilin Liang, Taipin Guo, Feng Wu, Yujie Gao, Mingkai Dong, Jie Yang, Ying Li, Qiyong Gong, Fanrong Liang, Jian Kong
The aims of this study were to 1) compare resting state functional connectivity (rs-fc) of the periaqueductal gray (PAG), a key region in the descending pain modulatory system (DPMS) between migraine without aura (MwoA) patients and healthy controls (HC), and 2) investigate how an effective treatment can influence the PAG rs-fc in MwoA patients. One hundred MwoA patients and forty-six matched HC were recruited. Patients were randomized to verum acupuncture, sham acupuncture, and waiting list groups. Resting state fMRI data were collected and seed based functional connectivity analysis was applied...
February 3, 2016: Scientific Reports
https://www.readbyqxmd.com/read/26799679/modulation-of-hand-motor-related-area-during-motor-imagery-and-motor-execution-before-and-after-middle-2-5-of-the-ms6-line-scalp-acupuncture-stimulation-an-fmri-study
#19
Zanardi Romeo, Maieron Marta, Tomasino Barbara
Scalp acupuncture (SA) combines the concept of cerebral cortex organization with the principles of acupuncture. The SA stimulates sections of the cerebral cortex. We studied the functional modulation of the left hand sensorimotor area induced by SA in order to investigate the specificity of the SA-related functional effects of the middle 2/5 of the MS6 line of the left side, which corresponds to the upper limb motor segment of the primary motor area. To this purpose, we compared the pre- and post-SA functional activation patterns during an implicit motor imagery task (handedness decision in which participants simulated rotational hand movements) and an explicit manual motor execution task...
March 2016: Brain and Cognition
https://www.readbyqxmd.com/read/26790206/-mri-pain-matrix-regional-homogeneity-in-cervical-spondylosis-of-neck-type-treated-with-acupuncture-at-multiple-acupoints
#20
RANDOMIZED CONTROLLED TRIAL
Weicui Chen, Xiaoyan Hou, Jun Chen, Delong Zhang, Guoxi Ye, Chenlin Lin, Xian Liu, Jianhua Liu, Bo Liu
OBJECTIVE: To observe the impacts on pain matrix (PM) brain area in the patients of cervical spondylosis of neck type treated with acupuncture at single point and the multiple points. METHODS: Forty-nine patients of cervical spondylosis of neck type were randomized into a single-point group (25 cases) and a multiple-point group (24 cases), and treated with acupuncture at Bailao (EX-HN 15) singly or Bailao (EX-HN 15) and Hegu (LI 4) in combination correspondingly...
October 2015: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
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