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https://www.readbyqxmd.com/read/29338895/feasibility-of-total-intravenous-anesthesia-by-cardiologists-with-the-support-of-anesthesiologists-during-catheter-ablation-of-atrial-fibrillation
#1
Takanori Yamaguchi, Yusuke Shimakawa, Shinji Mitsumizo, Akira Fukui, Yuki Kawano, Toyokazu Otsubo, Yuya Takahashi, Kei Hirota, Takeshi Tsuchiya, Kenichi Eshima
BACKGROUND: The optimal methodology for sedation and anesthesia during atrial fibrillation (AF) ablation has not been well established. We assessed the feasibility of total intravenous anesthesia (TIVA) by cardiologists with support from anesthesiologists during AF ablation and quality of pulmonary vein isolation (PVI) and single procedure success rate at 12 months. METHODS: TIVA was performed by cardiologists using IV propofol and fentanyl under controlled ventilation via i-gel™ without neuromuscular blocking drugs in 160 consecutive patients (80 nonparoxysmal) with no anticipated difficult airway or other severe diseases...
January 12, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29306222/superiorly-based-nasolabial-island-flap-for-reconstruction-of-the-lateral-lower-eyelid
#2
Sedat Tatar, Yalçın Yontar, Selahattin Özmen
Background/aim: Various flap procedures have been described and used for the lower eyelids; however, the nasolabial flap is rarely employed. We herein aimed to present the clinical results of using the superiorly based nasolabial island flap for repair of surgical defects extending to the lateral lower eyelid. Materials and methods: Nine patients with a mean age of 62 +- 6 years underwent surgery for reconstruction of the lower eyelid.Results: The diagnosis of lesions was nodular basal-cell carcinoma (n = 5), superficial basal-cell carcinoma (n = 1), well-differentiated squamous-cell carcinoma (n = 1), and basosquamous-cell carcinoma (n = 2)...
December 19, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29304735/effect-of-single-dose-dexmedetomidine-on-postoperative-recovery-after-ambulatory-ureteroscopy-and-ureteric-stenting-a-double-blind-randomized-controlled-study
#3
I I Shariffuddin, W H Teoh, S Wahab, C Y Wang
BACKGROUND: Ambulatory surgery has recently gain popularity, as it is a good method of optimizinghospital resources utilization. To support ambulatory surgery, anaesthetic goals nowrevolve around patients' early recovery with minimal pain and nausea, expedientdischarge home and prompt resumption of activities of daily living. In this study, weevaluated the effect of a single pre-induction dose of dexmedetomidine on anaestheticrequirements, postoperative pain and clinical recovery after ambulatory ureteroscopy andureteric stenting under general anaesthesia...
January 5, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/29284877/intravenous-dexmedetomidine-infusion-compared-with-that-of-fentanyl-in-patients-undergoing-arthroscopic-shoulder-surgery-under-general-anesthesia
#4
Mona Hossam Eldin Abdel Hamid
Background: Anesthesia for arthroscopic shoulder surgery is challenging due to the need for oligaemic surgical field as well as a good postoperative recovery profile. Aim: The present study was prospective, randomized to evaluate the efficacy of dexmdetomidine infusion compared to that of fentanyl in patients undergoing arthroscopic shoulder surgery under general anesthesia. Patients and Methods: A total of 60 patients aged from thirty to fifty years, American Society of Anesthesiologists Class I/II of either sex for arthroscopic shoulder surgery, were included...
October 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29245269/volatile-sedation-in-the-intensive-care-unit-a-systematic-review-and-meta-analysis
#5
Ha Yeon Kim, Ja Eun Lee, Ha Yan Kim, Jeongmin Kim
BACKGROUND: Volatile sedation in the intensive care unit (ICU) may reduce the number of adverse events and improve patient outcomes compared with intravenous (IV) sedation. We performed a systematic review and meta-analysis comparing the effects of volatile and IV sedation in adult ICU patients. METHODS: We searched the PubMed, Embase, Cochrane Central Register, and Web of Science databases for all randomized trials comparing volatile sedation using an anesthetic-conserving device (ACD) with IV sedation in terms of awakening and extubation times, lengths of ICU and hospital stay, and pharmacologic end-organ effects...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29241081/does-misuse-lead-to-a-disorder-the-misuse-of-prescription-tranquilizer-and-sedative-medications-and-subsequent-substance-use-disorders-in-a-u-s-longitudinal-sample
#6
C J Boyd, B West, S E McCabe
OBJECTIVES: We used two waves of National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) data and examined whether the misuse of prescription tranquilizers or sedatives at Wave 1 was associated with either continued misuse, tranquilizer/sedative use disorder, or other substance use disorder (SUD) at Wave 2. METHODS: Prospective data were analyzed from structured diagnostic interviews using the Alcohol Use disorders and Associated Disabilities Interview Schedule: DSM-IV Version (AUDADIS-DSM-IV)...
November 28, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29240609/effects-of-propofol-on-cellular-bioenergetics-in-human-skeletal-muscle-cells
#7
Adéla Krajčová, Nils Gunnar Løvsletten, Petr Waldauf, Vladimír Frič, Moustafa Elkalaf, Tomáš Urban, Michal Anděl, Jan Trnka, G Hege Thoresen, František Duška
OBJECTIVES: Propofol may adversely affect the function of mitochondria and the clinical features of propofol infusion syndrome suggest that this may be linked to propofol-related bioenergetic failure. We aimed to assess the effect of therapeutic propofol concentrations on energy metabolism in human skeletal muscle cells. DESIGN: In vitro study on human skeletal muscle cells. SETTINGS: University research laboratories. SUBJECTS: Patients undergoing hip surgery and healthy volunteers...
December 13, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/29208583/challenging-anaesthetic-management-of-captive-reindeer-rangifer-tarandus-report-of-4-cases
#8
P Monticelli, A McSloy, U Morath, C Adami
Four captive reindeer underwent anaesthesia to allow dehorning or drainage of lymph nodes abscessation. Premedication was based on xylazine (dose range: 0.075- 0.5 mg/kg, IM or IV), with or without ketamine (dose range: 1-2 mg/kg, IM or IV), all of which failed to produce effective sedation without side effects. During anaesthesia, 2 reindeer experienced severe hypoxaemia and hypoventilation. Recovery was smooth in 3 out 4 animals, but delayed in one reindeer sedated with 0.5 mg/kg of xylazine IV; this patient required repeated atipamezole administrations (0...
December 2017: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/29197208/occurrence-of-post-injection-delirium-sedation-syndrome-after-application-of-olanzapine-long-acting-injection-during-one-year-period
#9
Suzana Uzun, Oliver Kozumplik, Ivan Ćelić, Nela Pivac, Ninoslav Mimica
INTRODUCTION: The aim was to report the occurrence of after application of olanzapine long-acting injection (OLAI) in patients with schizophrenia during one year period. SUBJECTS AND METHODS: During one year period, OLAI was applied to 30 patients with schizophrenia (18 men, 12 women) who were non-adherent to previous treatment with oral olanzapine. Patients were 20-58 years of age (39 years old on average), diagnosed with SCID based on DSM-IV-TR criteria. Patients received OLAI in dosage between 210-405 mg (287±62 (mean ± SD)) every 2-4 weeks...
December 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/29189311/role-of-preemptive-gabapentin-on-postoperative-analgesia-after-infraumbilical-surgeries-under-subarachnoid-block-a-randomized-placebo-controlled-double-blind-study
#10
Gaurav S Tomar, Farhat Singh, Grace Cherian
BACKGROUND: Preemptive use of gabapentin might accelerate recovery by reducing acute post-inguinal herniorrhaphy pain and opioid requirement being an analgesic. STUDY QUESTION: Assessing efficacy of three different doses of oral gabapentin premedication for postoperative pain management after inguinal herniorrhaphy under spinal anesthesia. STUDY DESIGN: This prospective, randomized, placebo controlled study was performed on 120 male patients (ASA I/II) undergoing inguinal herniorrhaphy under subarachnoid block...
November 14, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/29188907/prescribing-patterns-in-a-psychiatrically-referred-sample-of-youth-with-autism-spectrum-disorder
#11
Julia Shekunov, Janet Wozniak, Kristina Conroy, Elizabeth Pinsky, Maura Fitzgerald, Melissa F de Leon, Abigail Belser, Joseph Biederman, Gagan Joshi
OBJECTIVE: The aim of this study was to examine the pattern of psychopharmacologic interventions in a psychiatrically referred sample of youth with autism spectrum disorder (ASD). METHODS: This retrospective chart review aimed at collecting demographic and clinical information, including data on DSM-IV-TR criteria-based psychiatric disorders and related current medication treatment and response. Data were collected in December 2011. Clinicians identified the target disorder for each medication and any adverse events...
November 28, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29184758/atlantoaxial-rotatory-displacement-in-children
#12
David Spiegel, Shikshya Shrestha, Prakash Sitoula, Norma Rendon, John Dormans
AIM: To correlate the Pang and Lee class with the clinical course in a consecutive series of patients presenting with painful torticollis. METHODS: Forty-seven dynamic rotational computed tomography (CT) scans in 35 patients were classified into one of the five types defined by Pang and Li, including types I (atlantoaxial rotatopry fixation), II ("pathologic stickiness" without crossover of C1 on C2), III ("pathologic stickiness" with crossover of C1 on C2), IV (normal or muscular torticollis), and V (diagnostic grey zone)...
November 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/29183660/comparison-of-the-sedative-effects-of-nalbuphine-and-butorphanol-alone-or-in-combination-with-acepromazine-in-dogs
#13
Viviane H Gomes, Renato Ls Oliveira, Juliana Lr Marques, Cassia Mm Coelho, Marta Fa Silva
OBJECTIVE: To compare sedation and effects on heart rate (HR), mean arterial pressure (MAP) and respiratory rate (fR) of nalbuphine and butorphanol, alone or combined with acepromazine in dogs. STUDY DESIGN: Prospective, randomized experimental trial. ANIMALS: Eight healthy Beagle dogs, aged (mean ± standard deviation) 3.4 ± 0.5 years and weighing 11.0 ± 1.3 kg. METHODS: Each dog was treated four times: physiological saline (1 mL) combined with nalbuphine (0...
September 15, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/29182386/in-vivo-evaluation-of-effects-of-sedation-on-results-of-acoustoelastography-of-the-superficial-digital-flexor-tendons-in-clinically-normal-horses
#14
Diego De Gasperi, Samantha L Dzierzak, Peter Muir, Ray Vanderby, Sabrina H Brounts
OBJECTIVE To assess the effects of sedation on results of acoustoelastography of the superficial digital flexor tendons (SDFTs) in clinically normal horses. ANIMALS 27 clinically normal horses. PROCEDURES For each horse, the pathology index (PI) for the SDFT of each thoracic limb was determined by use of acoustoelastography at 4 locations (5, 10, 15, and 20 cm distal to the accessory carpal bone). Horses were evaluated before and after they were sedated with a combination of detomidine hydrochloride (0.01 mg/kg, IV) and butorphanol tartrate (0...
December 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/29181718/willingness-of-breast-cancer-patients-to-undergo-biopsy-and-breast-cancer-clinicians-practices-around-seeking-biopsy-at-the-time-of-breast-cancer-relapse
#15
Caroline Lohrisch, Mia Francl, Sophie Sun, Diego Villa, Karen A Gelmon
PURPOSE: The practice of seeking a biopsy to confirm a metastatic relapse of a prior breast cancer is individualized. Tumor samples have well-recognized importance in clinical and translational research, but also an increasing role in routine care. We sought to determine the attitudes of patients and breast cancer clinicians about biopsy at breast cancer relapses. METHODS: Consenting breast cancer patients and clinicians completed questionnaires with scenarios of decreasing personal benefit and increasing discomfort or inconvenience associated with biopsy at relapse of a prior breast cancer...
November 27, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29181332/intravenous-midazolam-as-more-effective-than-propofol-for-preventing-pruritus-after-intrathecal-sufentanil-in-surgical-patients-a-randomized-blinded-trial
#16
Jalil Makarem, Seyed Mohammad Mireskandari, Afshin Jafarzadeh, Laya Rahbar Nikoukar, Sara Aghaii
Background: Pruritus is a troublesome side effect of intrathecal opioids. Midazolam can reinforce GABA-mediated inhibition of the medullary dorsal horn neurons, and thus theoretically has potential to suppress opioid-induced pruritus. Objectives: This prospective double-blinded randomized trial aimed at comparing the effects of propofol, midazolam, and a combination of the two on the prevention of pruritus induced by intrathecal sufentanil. Methods: Eighty-four patients undergoing spinal anesthesia with 3 mL hyperbaric bupivacaine 0...
June 2017: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/29179227/-on-the-risk-of-dependence-on-gabapentinoids
#17
Udo Bonnet, Norbert Scherbaum
In the last ten years, the prescriptions of the gabapentinoids gabapentin and pregabalin increased largely also in Germany. Since several national and international pharmacovigilance-databases have warned for abuse liabilities and overdose fatalities in association with both gabapentinoids, which moreover, became to be sold on internet and black-markets, their addictive power has been subject to an ongoing clinical debate. As pre- and post-approval clinical trials did not reveal significant signs of dependence on gabapentin or pregabalin, we systematically searched in PubMed and Scopus for clinical studies and case reports being associated with abuse of and dependence on these drugs...
November 27, 2017: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/29175014/influence-of-sedation-on-onset-and-quality-of-euthanasia-in-sheep
#18
Michele Barletta, Erik H Hofmeister, John F Peroni, Merrilee Thoresen, Alexandra M Scharf, Jane E Quandt
The purpose of this study was to determine if dexmedetomidine administered IV prior to euthanasia in sheep affected the speed or quality of euthanasia. Twenty clinically healthy Dorset-cross adult ewes between 1 and 3years of age were enrolled in a randomized blinded experimental trial. The subjects were randomly assigned to receive dexmedetomidine 5μg/kg IV or an equivalent volume of saline. Five minutes later, euthanasia was accomplished with a pentobarbital/phenytoin overdose given IV. The time to apnea, asystole, cessation of audible heartbeat, and absence of corneal reflex were recorded by two blinded investigators...
November 21, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/29174961/effect-of-premedication-with-butorphanol-or-methadone-on-ease-of-endoscopic-duodenal-intubation-in-dogs
#19
William Jm McFadzean, Edward J Hall, Hugo van Oostrom
OBJECTIVE: The effect of premedication with butorphanol or methadone on ease of endoscopic duodenal intubation. STUDY DESIGN: Prospective, randomized, blinded clinical trial. ANIMALS: A group of 20 client-owned dogs. METHODS: Dogs were assigned randomly to be administered intravenous (IV) premedication with either butorphanol (0.4 mg kg-1) or methadone (0.3 mg kg-1). General anaesthesia was induced with propofol to effect and maintained with isoflurane in 100% oxygen...
June 7, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/29167040/delirium-in-the-intensive-care-setting-and-the-richmond-agitation-and-sedation-scale-rass-drowsiness-increases-the-risk-and-is-subthreshold-for-delirium
#20
Soenke Boettger, David Garcia Nuñez, Rafael Meyer, André Richter, Susana Franco Fernandez, Alain Rudiger, Maria Schubert, Josef Jenewein
INTRODUCTION: Sedation is a core concept in the intensive care setting, however, the impact of sedation on delirium has not yet been studied to date. METHODS: In this prospective cohort study, 225 patients with Richmond Agitation and Sedation (RASS) scores of -1 - drowsiness and 0 - alert- and calmness were assessed with the Delirium Rating Scale-Revised 1998 (DRS-R-98) and DSM-IV-TR-determined diagnosis of delirium assessing drowsiness versus alertness. RESULTS: By itself, drowsiness increased the odds for developing delirium eightfold (OR 7...
December 2017: Journal of Psychosomatic Research
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