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https://www.readbyqxmd.com/read/28088106/uv-a-induced-delayed-development-in-the-larvae-of-coral-seriatopora-caliendrum
#1
Jie Zhou, Tung-Yung Fan, John Beardall, Kunshan Gao
Coral reefs are vulnerable to ultraviolet radiation (UVR, 280-400nm). Not only do the fluxes of UVR fluctuate daily, they are also increasing due to global ocean and atmospheric changes. The deleterious effects of UVR on scleractinian corals have been intensively studied, but much less is known about the response of corals in the early pre-settlement phase. In this study, we tested how UVR exposure affects survival and development of Seriatopora caliendrum larvae and examined the photophysiological changes induced in the symbiotic dinoflagellate Symbiodinium...
January 4, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28087179/value-of-serum-n-terminal-b-type-natriuretic-peptide-in-asymptomatic-structural-heart-disease-in-taiwanese-population-comparisons-with-current-esc-guidelines
#2
Ta-Chuan Hung, Kuang-Te Wang, Chun-Ho Yun, Jen-Yuan Kuo, Charles Jia-Yin Hou, Chia-Yuan Liu, Tung-Hsin Wu, Hiram G Bezerra, Hsiao-Yang Cheng, Chung-Lieh Hung, Hung-I Yeh
BACKGROUND: The relationship between N-terminal pro-brain natriuretic peptide (NT-proBNP) and cardiac structural or functional anomalies in pre-clinical, asymptomatic Asian populations has not been well identified. METHODS: From October 2005 to March 2008, we enrolled consecutive asymptomatic adults with preserved global left ventricular (LV) function (ejection fraction>50%) who underwent annual cardiovascular health survey. Circulating NT-proBNP was used to identify echo-defined cardiac structural/functional anomalies and compared to current recommended cut-off from the European Society of Heart Failure...
December 29, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28077134/endoscopy-assisted-surgery-for-the-management-of-benign-breast-tumors-technique-learning-curve-and-patient-reported-outcome-from-preliminary-323-procedures
#3
Hung-Wen Lai, Hui-Yu Lin, Shu-Ling Chen, Shou-Tung Chen, Dar-Ren Chen, Shou-Jen Kuo
BACKGROUND: Endoscopy-assisted breast surgery (EABS), a technique that optimizes cosmetic outcome because it is performed through small wounds hidden in inconspicuous areas, could be an alternative surgical technique for benign breast tumors. In this study, we report the preliminary results of 323 EABS procedures performed at our institution for the management of benign breast tumors. METHODS: The medical records of patients who underwent EABS for benign breast lesions during the periods August 2010 to December 2015 were collected from the Changhua Christian Hospital EABS database...
January 11, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28074949/new-compounds-from-a-hydrothermal-vent-crab-associated-fungus-aspergillus-versicolor-xz-4
#4
Chengqian Pan, Yutong Shi, Xuegang Chen, Chen-Tung Arthur Chen, Xinyi Tao, Bin Wu
Three new quinazoline derivatives (1-3), one new oxepin-containing natural product (4) and four new cyclopenin derivatives (5-7 and 9) have been isolated from an EtOAc extract of the Taiwan Kueishantao hydrothermal vent crab-associated fungus Aspergillus versicolor XZ-4. Their planar structures were established by HRMS, 1D and 2D NMR spectroscopic data analyses. The absolute configurations for compounds 1 and 4 were determined by chiral phase HPLC analysis of their hydrolysis products. The absolute configurations of 2, 3 and 7 were defined mainly by comparison of the quantum chemical TDDFT calculated and the experimental ECD spectra, and the absolute configuration of 5 was deduced from comparison of the optical rotation values reported in the literature...
January 11, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28073557/diatom-nitzschia-navis-varingica-bacillariophyceae-and-its-domoic-acid-production-from-the-mangrove-environments-of-malaysia
#5
Suh Nih Tan, Sing Tung Teng, Hong Chang Lim, Yuichi Kotaki, Stephen S Bates, Chui Pin Leaw, Po Teen Lim
The distribution of the toxic pennate diatom Nitzschia was investigated at four mangrove areas along the coastal brackish waters of Peninsular Malaysia. Eighty-two strains of N. navis-varingica were isolated and established, and their identity confirmed morphologically and molecularly. Frustule morphological characteristics of the strains examined are identical to previously identified N. navis-varingica, but with a sightly higher density of the number of areolae per 1μm (4-7 areolae). Both LSU and ITS rDNAs phylogenetic trees clustered all strains in the N...
December 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073527/new-scenario-for-speciation-in-the-benthic-dinoflagellate-genus-coolia-dinophyceae
#6
Chui Pin Leaw, Toh Hii Tan, Hong Chang Lim, Sing Tung Teng, Hwa Lin Yong, Kirsty F Smith, Lesley Rhodes, Matthias Wolf, William C Holland, Mark W Vandersea, R Wayne Litaker, Patricia A Tester, Haifeng Gu, Gires Usup, Po Teen Lim
In this study, inter- and intraspecific genetic diversity within the marine harmful dinoflagellate genus Coolia Meunier was evaluated using isolates obtained from the tropics to subtropics in both Pacific and Atlantic Ocean basins. The aim was to assess the phylogeographic history of the genus and to clarify the validity of established species including Coolia malayensis. Phylogenetic analysis of the D1-D2 LSU rDNA sequences identified six major lineages (L1-L6) corresponding to the morphospecies Coolia malayensis (L1), C...
May 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073379/tau-passive-immunization-inhibits-not-only-tau-but-also-a%C3%AE-pathology
#7
Chun-Ling Dai, Yunn Chyn Tung, Fei Liu, Cheng-Xin Gong, Khalid Iqbal
BACKGROUND: Accumulation of hyperphosphorylated tau protein is a histopathological hallmark of Alzheimer's disease (AD) and related tauopathies. Currently, there is no effective treatment available for these progressive neurodegenerative diseases. In recent years, tau immunotherapy has shown great potential in animal models. We report the effect of immunization with tau antibodies 43D against tau 6-18 and 77E9 against tau 184-195 on tau and amyloid-β (Aβ) pathologies and cognition in triple-transgenic (3×Tg)-AD mice at mild to moderate stages of the disease...
January 10, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/28072531/discovery-of-2-1r-4r-4-4-chlorophenyl-phenyl-carbamoyl-oxy-methyl-cyclohexyl-methoxy-acetate-ralinepag-an-orally-active-prostacyclin-receptor-agonist-for-the-treatment-of-pulmonary-arterial-hypertension
#8
Thuy-Anh Tran, Bryan Kramer, Young-Jun Shin, Pureza Vallar, P Douglas Boatman, Ning Zou, Carleton R Sage, Tawfik Gharbaoui, Ashwin Krishnan, Biman Pal, Sagar R Shakya, Antonio Garrido Montalban, John Wesley Adams, Juan Ramirez, Dominic Peter Behan, Anna Shifrina, Anthony Blackburn, Tina Leakakos, Yunqing Shi, Michael Morgan, Abu Sadeque, Weichao Chen, David John Unett, Ibragim Gaidarov, Xiaohua Chen, Steve Chang, Hsin-Hui Shu, Shiu-Feng Tung, Graeme Semple
The design and synthesis of a new series of potent non-prostanoid IP receptor agonists that showed oral efficacy in the rat monocrotaline model of pulmonary arterial hypertension (PAH) is described. Detailed profiling of a number of analogues resulted in the identification of 3c (APD811, Ralinepag) that has good selectivity in both binding and functional assays with respect to most members of the prostanoid receptor family, and a more modest 40- 50-fold selectivity over the EP3 receptor. In our hands, its potency and efficacy are superior in vitro to MRE269 (the active metabolite of the clinical compound NS-304) in multiple in vitro measures of IP receptor mediated cAMP signaling...
January 10, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28068837/immediate-effects-of-acupuncture-treatment-on-intra-and-inter-limb-contributions-to-body-support-during-gait-in-patients-with-bilateral-medial-knee-osteoarthritis
#9
Yen-Hung Liu, I-Pin Wei, Ting-Ming Wang, Tung-Wu Lu, Jaung-Geng Lin
Knee osteoarthritis (OA) often leads to altered balance control, joint motion and loading patterns during gait. Acupuncture has been proven to be effective in pain relief but its effects on inter-joint load-sharing for body balance have not been reported. The current study bridged the gap by quantifying the immediate effects of acupuncture on the inter-joint and inter-limb load-sharing in patients with knee OA during level walking in terms of the total support moment (Ms) and the contribution of individual joints to the total support moment...
January 9, 2017: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/28068431/cil-102-induced-cell-cycle-arrest-and-apoptosis-in-colorectal-cancer-cells-via-upregulation-of-p21-and-gadd45
#10
Wen-Shih Huang, Yi-Hung Kuo, Hsing-Chun Kuo, Meng-Chiao Hsieh, Cheng-Yi Huang, Ko-Chao Lee, Kam-Fai Lee, Chien-Heng Shen, Shui-Yi Tung, Chih-Chuan Teng
CIL-102 (1-[4-(furo[2,3-b]quinolin-4-ylamino)phenyl]ethanone) is a well-known, major active agent of the alkaloid derivative of Camptotheca acuminata with valuable biological properties, including anti-tumorigenic activity. In this study, we investigated the molecular mechanisms by which CIL-102 mediated the induction of cell death, and we performed cell cycle G2/M arrest to clarify molecular changes in colorectal cancer cells (CRC). Treatment of DLD-1 cells with CIL-102 resulted in triggering the extrinsic apoptosis pathway through the activation of Fas-L, caspase-8 and the induction of Bid cleavage and cytochrome c release in a time-dependent manner...
2017: PloS One
https://www.readbyqxmd.com/read/28066961/lifestyle-changes-in-heart-transplant-recipients
#11
Yi-Chen Wu, Heng-Hsin Tung, Fu-Chih Lai, Jeng Wei, Shu-Yuan Liang, Shu-Fang Wu
The purpose of this study was to understand the lifestyle; examine the relationships among lifestyle, medical factors, and stress status; and determine the predictors of better lifestyle in heart transplant recipients in Taiwan. A prospective design with convenience sampling was used. Data were collected through the Health-Promoting Lifestyle Profile-II and demographic questionnaires, which included personal information, stress status, and medical information. Pearson correlations, 1-way analysis of variance, independent t tests, paired t tests, and hierarchical regression were used to analyze the factors related to better lifestyle...
January 8, 2017: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/28065841/the-neurotoxic-mechanisms-of-amphetamine-step-by-step-for-striatal-dopamine-depletion
#12
Che-Se Tung, Shang-Tang Chang, Chuen-Lin Huang, Nai-Kuei Huang
Amphetamine (AMPH) is a commonly abused psychostimulant that induces neuronal cell death/degeneration in humans and experimental animals. Although multiple neurotoxic mechanisms of AMPH have been intensively investigated, the interplay between these mechanisms has remained elusive. In this study, we used a rat model of AMPH-induced long-lasting striatal dopamine (DA) depletion and identified mechanisms of neurotoxicity, energy failure, excitotoxicity, and oxidative stress. Pretreatment with nicotinamide (NAM, a co-factor for the electron transport chain) blocked AMPH-induced free radical formation, energy failure, and striatal DA decrease...
January 5, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28065516/ignition-interlock-laws-effects-on-fatal-motor-vehicle-crashes-1982-2013
#13
Emma E McGinty, Gregory Tung, Juliana Shulman-Laniel, Rose Hardy, Lainie Rutkow, Shannon Frattaroli, Jon S Vernick
INTRODUCTION: Alcohol-involved motor vehicle crashes are a major cause of preventable mortality in the U.S., leading to more than 10,000 fatalities in 2013. Ignition interlocks, or alcohol-sensing devices connected to a vehicle's ignition to prevent it from starting if a driver has a predetermined blood alcohol content (BAC) level, are a promising avenue for preventing alcohol-involved driving. This study sought to assess the effects of laws requiring ignition interlocks for some or all drunk driving offenders on alcohol-involved fatal crashes...
December 27, 2016: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28064433/magnetic-vt-study-a-prospective-multicenter-post-market-randomized-controlled-trial-comparing-vt-ablation-outcomes-using-remote-magnetic-navigation-guided-substrate-mapping-and-ablation-versus-manual-approach-in-a-low-lvef-population
#14
Luigi Di Biase, Roderick Tung, Tamás Szili-Torok, J David Burkhardt, Peter Weiss, Rene Tavernier, Adam E Berman, Erik Wissner, William Spear, Xu Chen, Petr Neužil, Jan Skoda, Dhanunjaya Lakkireddy, Bruno Schwagten, Ken Lock, Andrea Natale
PURPOSE: Patients with ischemic cardiomyopathy (ICM) are prone to scar-related ventricular tachycardia (VT). The success of VT ablation depends on accurate arrhythmogenic substrate localization, followed by optimal delivery of energy provided by constant electrode-tissue contact. Current manual and remote magnetic navigation (RMN)-guided ablation strategies aim to identify a reentry circuit and to target a critical isthmus through activation and entrainment mapping during ongoing tachycardia...
January 7, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/28059408/nano-sized-graphene-flakes-insights-from-experimental-synthesis-and-first-principles-calculations
#15
Pin-Chun Lin, Yi-Rui Chen, Kuei-Ting Hsu, Tzu-Neng Lin, Kuo-Lun Tung, Ji-Lin Shen, Wei-Ren Liu
In this study, we proposed a cost-effective method for preparing graphene nano-flakes (GNFs) derived from carbon nanotubes (CNTs) via three steps (pressing, homogenization and sonication exfoliation processes). Scanning electron microscopy (SEM), transmission electron microscopy (TEM), atomic force microscopy (AFM), laser scattering, as well as ultraviolet-visible and photoluminescence (PL) measurements were carried out. The results indicated that the size of as-synthesized GNFs was approximately 40-50 nm. Furthermore, we also used first principles calculations to understand the transformation from CNTs to GNFs from the viewpoints of the edge formation energies of GNFs in different shapes and sizes...
January 6, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28058017/dysphagia-after-vertical-sleeve-gastrectomy-evaluation-of-risk-factors-and-assessment-of-endoscopic-intervention
#16
Anand Nath, Sayali Yewale, Tung Tran, John S Brebbia, Timothy R Shope, Timothy R Koch
AIM: To evaluate the risks of medical conditions, evaluate gastric sleeve narrowing, and assess hydrostatic balloon dilatation to treat dysphagia after vertical sleeve gastrectomy (VSG). METHODS: VSG is being performed more frequently worldwide as a treatment for medically-complicated obesity, and dysphagia is common post-operatively. We hypothesize that post-operative dysphagia is related to underlying medical conditions or narrowing of the gastric sleeve. This is a retrospective, single institution study of consecutive patients who underwent sleeve gastrectomy from 2013 to 2015...
December 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28056702/management-of-venous-ulcers-according-to-their-anatomical-relationship-with-varicose-veins
#17
Yun-Nan Lin, Tung-Ying Hsieh, Shu-Hung Huang, Chia-Ming Liu, Kao-Ping Chang, Sin-Daw Lin
Background Adequately excising varicose and incompetent perforating veins is necessary for reducing their recurrence rate of venous ulcer. Method In total, 66 venous ulcers (C6) in 1083 legs with primary varicose veins were managed through endoscopic-assisted surgery. In an endoscopic operative view, the nonvaricose, varicose, and incompetent perforating veins were clearly visualized and precisely dissected. The varicose and incompetent perforating veins were divided and completely excised. Result The varicose veins were traced to the base or periphery of the 55 ulcers...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28052521/a-bioluminogenic-probe-for-monitoring-tyrosinase-activity
#18
Jianguang Wang, Taesup Lee, Zhe Zhang, Ching Tung
A novel bioluminogenic probe, based on luciferin, was designed and synthesized to monitor tyrosinase activity. Its applications were demonstrated in assessing tyrosinase activity in a buffered aqueous solution, and in measuring endogenous tyrosinase activity in melanoma cells.
January 3, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28049279/a-rapid-assessment-and-response-approach-for-socially-marketed-nutrition-commodities-in-viet-nam
#19
Tahir Turk, Nguyen Dinh Quang, Tran Thuy Nga, Huynh Phuong, Le Van Anh Tung, Vu Hoang Trang
BACKGROUND: The leading cause of death in children in developing countries is protein-energy malnutrition. In Viet Nam, 25.9% of children under 5 experience stunted growth and 6.6% are moderately wasted. Iron deficiency anaemia and vitamin A deficiency contribute to these and other malnutrition conditions. OBJECTIVES: Given these factors, more evidence based approaches are required to improve understanding of current attitudes, opinions and behaviours of mothers with young children, in order to operationalise social marketing of nutrition commodities in Viet Nam...
January 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28047899/su-f-t-453-improved-head-and-neck-sbrt-treatment-planning-using-planiq
#20
H Wang, C Wang, J Phan, S Tung, P Chi
PURPOSE: Treatment planning for Head and Neck(HN) re-irradiation is a challenge because of ablative doses to target volume and strict critical structure constraints. PlanIQ(Sun Nuclear Corporation) can assess the feasibility of clinical goals and quantitatively measure plan quality. Here, we assess whether incorporation of PlanIQ in our SBRT treatment planning process can improve plan quality and planning efficiency. METHODS: From 2013-2015, 35 patients (29 retrospective, 6 prospective) with recurrent HN tumors were treated with SBRT using VMAT treatment plans...
June 2016: Medical Physics
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