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https://www.readbyqxmd.com/read/28526828/gender-differences-in-the-association-between-moderate-alcohol-consumption-and-hearing-threshold-shifts
#1
Yuan-Yung Lin, Hsin-Chien Chen, Wen-Sen Lai, Li-Wei Wu, Chih-Hung Wang, Jih-Chin Lee, Tung-Wei Kao, Wei-Liang Chen
Hearing loss is a global public health problem with a high prevalence, significantly impairing communication and leading to a decrease in the quality of life. The association between moderate alcohol consumption (MAC) and hearing impairment has been addressed in several studies with inconsistent results. The intent of our study is to clarify the correlation between MAC and the hearing threshold and further investigate the interplay between MAC and the hearing threshold categorized by gender. The study included 4,075 participants aged 20-69 years from the 1999-2004 data of National Health and Nutrition Examination Survey (NHANES)...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28523606/frederick-yi-tung-cho-1939-2011-his-phd-days-in-biophysics-the-photosynthesis-lab-and-his-patents-in-engineering-physics
#2
Govindjee, John C Munday, George C Papageorgiou
We present here a Tribute to Frederick Yi-Tung Cho (1939-2011), an innovative and ingenious biophysicist and an entrepreneur. He was one of the 4 earliest PhD students [see: Cederstrand (1965)-Carl Nelson Cederstrand; coadvisor: Eugene Rabinowitch; Papageorgiou (1968)-George C. Papageorgiou (coauthor of this paper); and Munday (1968)-John C. Munday Jr. (also a coauthor of this paper)] of one of us (Govindjee) in Biophysics at the University of Illinois at Urbana-Champaign (UIUC) during the late 1960s (1963-1968)...
May 18, 2017: Photosynthesis Research
https://www.readbyqxmd.com/read/28522966/barratt-impulsivity-in-healthy-adults-is-associated-with-higher-gray-matter-concentration-in-the-parietal-occipital-cortex-that-represents-peripheral-visual-field
#3
Jaime S Ide, Hsiang C Tung, Cheng-Ta Yang, Yuan-Chi Tseng, Chiang-Shan R Li
Impulsivity is a personality trait of clinical importance. Extant research focuses on fronto-striatal mechanisms of impulsivity and how executive functions are compromised in impulsive individuals. Imaging studies employing voxel based morphometry highlighted impulsivity-related changes in gray matter concentrations in a wide array of cerebral structures. In particular, whereas prefrontal cortical areas appear to show structural alterations in individuals with a neuropsychiatric condition, the findings are less than consistent in the healthy population...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28520763/genome-wide-gene-expression-array-identifies-novel-genes-related-to-disease-severity-and-excessive-daytime-sleepiness-in-patients-with-obstructive-sleep-apnea
#4
Yung-Che Chen, Kuang-Den Chen, Mao-Chang Su, Chien-Hung Chin, Chung-Jen Chen, Chia-Wei Liou, Ting-Wen Chen, Ya-Chun Chang, Kuo-Tung Huang, Chin-Chou Wang, Ting-Ya Wang, Jen-Chieh Chang, Yong-Yong Lin, Yi-Xin Zheng, Meng-Chih Lin, Chang-Chun Hsiao
We aimed to identify novel molecular associations between chronic intermittent hypoxia with re-oxygenation and adverse consequences in obstructive sleep apnea (OSA). We analyzed gene expression profiles of peripheral blood mononuclear cells from 48 patients with sleep-disordered breathing stratified into four groups: primary snoring (PS), moderate to severe OSA (MSO), very severe OSA (VSO), and very severe OSA patients on long-term continuous positive airway pressure treatment (VSOC). Comparisons of the microarray gene expression data identified eight genes up-regulated with OSA and down-regulated with CPAP treatment, and five genes down-regulated with OSA and up-regulated with CPAP treatment...
2017: PloS One
https://www.readbyqxmd.com/read/28520696/an-ovine-model-of-hyperdynamic-endotoxemia-and-vital-organ-metabolism
#5
Liam Byrne, Nchafatso G Obonyo, Sara Diab, Kimble Dunster, Margaret Passmore, Ai Ching Boon, Louise See Hoe, Karen Hay, Frank Van Haren, John-Paul Tung, Louise Cullen, Kiran Shekar, Kathryn Maitland, John F Fraser
BACKGROUND: Animal models of endotoxemia are frequently used to understand the pathophysiology of sepsis and test new therapies. However, important differences exist between commonly used experimental models of endotoxemia and clinical sepsis. Animal models of endotoxemia frequently produce hypodynamic shock in contrast to clinical hyperdynamic shock. This difference may exaggerate the importance of hypoperfusion as a causative factor in organ dysfunction. This study sought to develop an ovine model of hyperdynamic endotoxemia and assess if there is evidence of impaired oxidative metabolism in the vital organs...
May 17, 2017: Shock
https://www.readbyqxmd.com/read/28514051/the-ppar%C3%AE-setd8-axis-constitutes-an-epigenetic-p53-independent-checkpoint-on-p21-mediated-cellular-senescence
#6
Chieh-Tien Shih, Yi-Feng Chang, Yi-Tung Chen, Chung-Pei Ma, Hui-Wen Chen, Chang-Ching Yang, Juu-Chin Lu, Yau-Sheng Tsai, Hua-Chien Chen, Bertrand Chin-Ming Tan
Cellular senescence is a permanent proliferative arrest triggered by genome instability or aberrant growth stresses, acting as a protective or even tumor-suppressive mechanism. While several key aspects of gene regulation have been known to program this cessation of cell growth, the involvement of the epigenetic regulation has just emerged but remains largely unresolved. Using a systems approach that is based on targeted gene profiling, we uncovered known and novel chromatin modifiers with putative link to the senescent state of the cells...
May 17, 2017: Aging Cell
https://www.readbyqxmd.com/read/28513721/programmable-micrometer-sized-motor-array-based-on-live-cells
#7
Shuangxi Xie, Xiaodong Wang, Niandong Jiao, Steve Tung, Lianqing Liu
Trapping and transporting microorganisms with intrinsic motility are important tasks for biological, physical, and biomedical applications. However, fast swimming speed makes the manipulation of these organisms an inherently challenging task. In this study, we demonstrated that an optoelectrical technique, namely, optically induced dielectrophoresis (ODEP), could effectively trap and manipulate Chlamydomonas reinhardtii (C. reinhardtii) cells swimming at velocities faster than 100 μm s(-1). Furthermore, live C...
May 17, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28513666/high-performance-solution-processable-tetrathienoacene-ttar-based-small-molecules-for-organic-field-effect-transistors-ofets
#8
Sureshraju Vegiraju, Deng-Yi Huang, Pragya Priyanka, Yo-Shan Li, Xian-Lun Luo, Shao-Huan Hong, Jen-Shyang Ni, Shih-Huang Tung, Chien-Lung Wang, Wei-Chieh Lien, Shueh Lin Yau, Cheng-Liang Liu, Ming-Chou Chen
Three new organic semiconductors with alkyl chain-substituted tetrathienoacene (TTAR) as the central core and both ends capped with thiophene (DT-TTAR), thienothiophene (DTT-TTAR) and dithienothiophene (DDTT-TTAR) have been synthesized and characterized for organic field effect transistor (OFET) applications. A hole mobility of 0.81 cm(2) V(-1) s(-1) was achieved for the DDTT-TTAR film, which represents the highest mobility yet found for a solution-processable p-type TTAR-based small molecular semiconductors...
May 17, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28513005/effects-of-argument-quality-source-credibility-and-self-reported-diabetes-knowledge-on-message-attitudes-an-experiment-using-diabetes-related-messages
#9
Tung-Cheng Lin, Lih-Lian Hwang, Yung-Jye Lai
BACKGROUND: Previous studies have reported that credibility and content (argument quality) are the most critical factors affecting the quality of health information and its acceptance and use; however, this causal relationship merits further investigation in the context of health education. Moreover, message recipients' prior knowledge may moderate these relationships. OBJECTIVES: This study used the elaboration likelihood model to determine the main effects of argument quality, source credibility and the moderating effect of self-reported diabetes knowledge on message attitudes...
May 17, 2017: Health Information and Libraries Journal
https://www.readbyqxmd.com/read/28507179/elevated-expression-of-the-nlrp3-inflammasome-and-its-correlation-with-disease-activity-in-adult-onset-still-disease
#10
Chia-Wei Hsieh, Yi-Ming Chen, Chi-Chen Lin, Kuo-Tung Tang, Hsin-Hua Chen, Wei-Ting Hung, Kuo-Lung Lai, Der-Yuan Chen
OBJECTIVE: The dysregulation of the NLRP3 (NLR containing a pyrin domain) inflammasome is involved in autoinflammatory diseases. Adult-onset Still disease (AOSD) is regarded as an autoinflammatory disease. However, the pathogenic involvement of NLRP3 inflammasome in AOSD remains unclear and NLRP3 activators in AOSD are currently unknown. METHODS: The mRNA expression of NLRP3 inflammasome signaling in peripheral blood mononuclear cells (PBMC) from 34 patients with AOSD and 14 healthy subjects was determined using quantitative-PCR (qPCR)...
May 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28506710/outcomes-after-repeat-ablation-of-ventricular-tachycardia-in-structural-heart-disease-an-analysis-from-the-international-vt-ablation-center-collaborative-group
#11
Wendy S Tzou, Roderick Tung, David S Frankel, Luigi Di Biase, Pasquale Santangeli, Marmar Vaseghi, T Jared Bunch, J Peter Weiss, Venkatakrishna N Tholakanahalli, Dhanunjaya Lakkireddy, Rama Vunnam, Timm Dickfeld, Nilesh Mathuria, Usha Tedrow, Pasquale Vergara, Kairav Vakil, Shiro Nakahara, J David Burkhardt, William G Stevenson, David J Callans, Paolo Della Bella, Andrea Natale, Kalyanam Shivkumar, Francis E Marchlinski, William H Sauer
BACKGROUND: Data evaluating repeat radiofrequency ablation (>1RFA) of ventricular tachycardia (VT) are limited. OBJECTIVE: The purpose of this study was to determine the safety and outcomes of VT >1RFA in patients with structural heart disease. METHODS: Patients with structural heart disease undergoing VT RFA at 12 centers with data on prior RFA history were included. Characteristics and outcomes were compared between first-time (1RFA) and >1RFA patients...
April 15, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28505456/self-polymerization-of-dopamine-in-acidic-environments-without-oxygen
#12
Tung-Po Chen, Tianchi Liu, Tsan-Liang Su, Jun-Feng Liang
An alkaline environment and the presence of oxygen are essential requirements for dopamine polymerization. In this study, we are the first to demonstrate the self-polymerization of dopamine through plasma-activated water (PAW) under acidic environments (pH<5.5). Resulting poly(dopamine) (PDA) were characterized using Nanosizer, SEM, FTIR, UV-vis, and fluorescence spectrophotometers and proved to have similar physical and chemical properties to those polymerized under a basic condition except that the PDA particles formed in PAW were more stable and hardly aggregated at varied pHs...
May 15, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28500947/electrochemical-latent-redox-ratiometric-probes-for-real-time-tracking-and-quantification-of-endogenous-hydrogen-sulfide-production-in-living-cells
#13
Kesavan Manibalan, Veerappan Mani, Pu-Chieh Chang, Chih-Hung Huang, Sheng-Tung Huang, Kasper Marchlewicz, Suresh Neethirajan
Hydrogen sulfide (H2S) was discovered as a third gasotransmitter in biological systems and recent years have seen a growing interest to understand its physiological and pathological functions. However, one major limiting factor is the lack of robust sensors to quantitatively track its production in real-time. We described a facile electrochemical assay based on latent redox probe approach for highly specific and sensitive quantification in living cells. Two chemical probes, Azido Benzyl ferrocene carbamate (ABFC) and N-alkyl Azido Benzyl ferrocene carbamate (NABFC) composed of azide trigger group were designed...
May 4, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28500443/genome-characterization-of-a-novel-megrivirus-related-avian-picornavirus-from-a-carnivorous-wild-bird-western-marsh-harrier-circus-aeruginosus
#14
Ákos Boros, Péter Pankovics, Róbert Mátics, Ádám Adonyi, Nóra Bolba, Tung Gia Phan, Eric Delwart, Gábor Reuter
In this study, the complete genome of a novel picornavirus called harrier picornavirus 1 (HaPV-1) strain harrier/MR-01/HUN/2014 (KY488458) was sequenced and analysed from a cloacal sample of a threatened, carnivorous wild bird, western marsh harrier (Circus aeruginosus). HaPV-1 was detectable from 2 of the 3 samples from harriers. HaPV-1 is phylogenetically related to megriviruses (genus Megrivirus) from domestic chicken, turkey and duck, showing a similar genome organization pattern; it also has an avian picornavirus-like "Unit A" motif in the 3' UTR...
May 12, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28500291/the-complete-chloroplast-genome-sequence-of-tung-tree-vernicia-fordii-organization-and-phylogenetic-relationships-with-other-angiosperms
#15
Ze Li, Hongxu Long, Lin Zhang, Zhiming Liu, Heping Cao, Mingwang Shi, Xiaofeng Tan
Tung tree (Vernicia fordii) is an economically important tree widely cultivated for industrial oil production in China. To better understand the molecular basis of tung tree chloroplasts, we sequenced and characterized its genome using PacBio RS II sequencing platforms. The chloroplast genome was sequenced with 161,528 bp in length, composed with one pair of inverted repeats (IRs) of 26,819 bp, which were separated by one small single copy (SSC; 18,758 bp) and one large single copy (LSC; 89,132 bp)...
May 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28499829/characteristics-of-traditional-chinese-medicine-usage-in-children-with-precocious-puberty-a-nationwide-population-based-study
#16
Yi-Chun Lin, Tung-Ti Chang, Husan-Ju Chen, Chung-Hsing Wang, Mao-Feng Sun, Hung-Rong Yen
ETHNOPHARMACOLOGICAL RELEVANCE: Precocious puberty (PP) occurs in children with the early onset of pubertal development leading to physical and psychological problems. Current medical treatment is expensive and has its side effects. However, little is known about the utilization of traditional Chinese medicine (TCM) among patients with PP. To characterize the application of TCM among these patients, we conducted a nationwide population-based study. MATERIALS AND METHODS: We used the Taiwanese National Health Insurance Research Database (NHIRD), to perform a nationwide population-based study...
May 9, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28499816/tumor-ablation-using-low-intensity-ultrasound-and-sound-excitable-drug
#17
Ching-Hsuan Tung, Myung Shin Han, Young Kim, Jianjun Qi, Brian E O'Neill
The cell membrane is a semi-fluid container that defines the boundary of cells, and provides an enclosed environment for vital biological processes. A sound excitable drug (SED) that is non-cytotoxic to cells is developed to disrupt the plasma membrane under gentle ultrasound insonation, 1MHz, 1W/cm(2). The frequency and power density of insonation are within the physical therapy and medical imaging windows; thus the applied ultrasound is safe and not harmful to tissues. The insertion of SEDs into the plasma membrane is not toxic to cells; however, the intruding SEDs weaken the membrane's integrity...
May 10, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28499327/impact-of-polyethyleneglycol-addition-on-diffusion-coefficients-in-binary-ionic-liquid-electrolytes-composed-of-dicationic-ionic-liquid-and-polyethyleneglycol
#18
Tzi-Yi Wu, Shyh-Gang Su, Chuen-Lin Chiu, Chung-Wen Kuo, Yi-Hsuan Tung
We conduct a comparative study of conductivity and diffusion coefficient of two dicationic ionic liquids (3,3'-(octane-1,8-diyl)bis(1-ethyl-3-imidazolium) bis(trifluoromethylsulfonyl)amide ([IMCI][TFSI], S1) and 3,3'-(2,2'-(ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(1-ethyl-3-imidazolium) bis(trifluoromethylsulfonyl)amide ([IMOI][TFSI], S2)) at various temperatures. The diffusion coefficients of cation and anion in ionic liquids (ILs) are determined using pulse gradient spin-echo nuclear magnetic resonance (PGSE-NMR) method...
May 12, 2017: Magnetic Resonance in Chemistry: MRC
https://www.readbyqxmd.com/read/28497903/semiconducting-nanowire-based-optoelectronic-fibers
#19
Wei Yan, Yunpeng Qu, Tapajyoti Das Gupta, Arouna Darga, Dang Tùng Nguyên, Alexis Gérald Page, Mariana Rossi, Michele Ceriotti, Fabien Sorin
The recent ability to integrate semiconductor-based optoelectronic functionalities within thin fibers is opening intriguing opportunities for flexible electronics and advanced textiles. The scalable integration of high-quality semiconducting devices within functional fibers however remains a challenge. It is difficult with current strategies to combine high light absorption, good microstructure and efficient electrical contact. The growth of semiconducting nanowires is a great tool to control crystal orientation and ensure a combination of light absorption and charge extraction for efficient photodetection...
May 12, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28497896/self-assembled-au-cdse-nanocrystal-clusters-for-plasmon-mediated-photocatalytic-hydrogen-evolution
#20
Run Shi, Yinhu Cao, Yanjun Bao, Yufei Zhao, Geoffrey I N Waterhouse, Zheyu Fang, Li-Zhu Wu, Chen-Ho Tung, Yadong Yin, Tierui Zhang
Plasmon-mediated photocatalytic systems generally suffer from poor efficiency due to weak absorption overlap and thus limited energy transfer between the plasmonic metal and the semiconductor. Herein, a near-ideal plasmon-mediated photocatalyst system is developed. Au/CdSe nanocrystal clusters (NCs) are successfully fabricated through a facile emulsion-based self-assembly approach, containing Au nanoparticles (NPs) of size 2.8, 4.6, 7.2, or 9.0 nm and CdSe quantum dots (QDs) of size ≈3.3 nm. Under visible-light irradiation, the Au/CdSe NCs with 7...
May 12, 2017: Advanced Materials
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