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JOURNAL ARTICLE
Jie Bai, Mengyang He, Eryuan Gao, Guang Yang, Chengxiu Zhang, Hongxi Yang, Jie Dong, Xiaoyue Ma, Yufei Gao, Huiting Zhang, Xu Yan, Yong Zhang, Jingliang Cheng, Guohua Zhao
OBJECTIVES: To evaluate the performance of multiparametric neurite orientation dispersion and density imaging (NODDI) radiomics in distinguishing between glioblastoma (Gb) and solitary brain metastasis (SBM). MATERIALS AND METHODS: In this retrospective study, NODDI images were curated from 109 patients with Gb (n = 57) or SBM (n = 52). Automatically segmented multiple volumes of interest (VOIs) encompassed the main tumor regions, including necrosis, solid tumor, and peritumoral edema...
March 15, 2024: European Radiology
#22
JOURNAL ARTICLE
Mónica Teixeira, Eugénia Castro, Nuno Medeiros, Paulo Pina, Sandra Alves, Pedro Oliveira
PURPOSE: Successful microlaryngeal surgery relies on an adequate laryngeal exposure. Recognizing the likelihood of challenging exposure prior to microlaryngeal surgery may assist in selecting the appropriate surgical approach and even prompt consideration of alternative treatment options. We aim to apply the mini-Laryngoscore, a preoperative assessment tool, to our study population and incorporate novel variables to optimize the prediction model. METHODS: This single-center prospective cohort study included 80 consecutive patients undergoing elective microlaryngeal surgery, from January 1, to June 30, 2023...
March 12, 2024: European Archives of Oto-rhino-laryngology
#23
JOURNAL ARTICLE
Marian Mikhael, Bhargav Kansara, Ameer Basta, Emma Hume, Oliver T Nguyen, Maija Reblin, Young-Rock Hong, Amir Alishahi Tabriz, Krupal Patel, Jeffery Scott Magnuson, Kea Turner
BACKGROUND: There has been limited study of oncology professionals' perspectives on optimizing delivery of presurgical education for individuals with head and neck cancer (HNC). Therefore, we assessed oncology professionals' perspectives about presurgical education for laryngectomy and free flap surgeries, which have a significant impact on patients' quality of life. METHODS: Interviews were conducted with 27 oncology professionals from an NCI-designated Comprehensive Cancer Center and a community oncology setting...
March 9, 2024: Head & Neck
#24
JOURNAL ARTICLE
Young Woo Song, Seung Ha Yoo, Ui-Won Jung
PURPOSE: The present experiment aimed to evaluate the placement accuracy of fully guided implant surgery using a mucosa-supported surgical guide when the protocol of osteotomy and installation was modified (MP) compared to when the protocol was sequentially and conventionally carried out (CP). MATERIALS AND METHODS: For 24 mandibular dentiform models, 12 dentists (6 experts and 6 beginners) performed fully guided implant placements two times at the right first and second molar sites using a mucosa-supported surgical guide, once by the CP (CP group) and at the other time by the MP (MP group)...
February 2024: Journal of Advanced Prosthodontics
#25
Kota Kagawa, Koji Iida, Akira Hashizume, Go Seyama, Akitake Okamura, Rofat Askoro, Nobutaka Horie
Stereotactic electroencephalography (SEEG) is an increasingly popular surgical modality for localizing the epileptogenic zone. Robot-guided stereotactic electrode placement has been covered in Japan by National Health Insurance since 2020. However, several surgical devices, such as the anchor bolt (a thin, hollow, metal shaft that serves as a guide screw or fixing for each electrode), have not been approved. A 14-year-old female who underwent SEEG for intractable epilepsy and required additional surgery to remove a retained depth electrode from the skull after the SEEG monitoring was finished...
2024: NMC Case Report Journal
#26
REVIEW
Carrie R Muh, Jessica R Dorilio, Cameron P Beaudreault, Patricia E McGoldrick, Jared M Pisapia, Steven M Wolf
PURPOSE: Stereoelectroencephalography (SEEG) is a diagnostic surgery that implants electrodes to identify areas of epileptic onset in patients with drug-resistant epilepsy (DRE). SEEG is effective in identifying the epileptic zone; however, placement of electrodes in very young children has been considered contraindicated due to skull thinness. The goal of this study was to evaluate if SEEG is safe and accurate in young children with thin skulls. METHODS: Four children under the age of two years old with DRE underwent SEEG to locate the region of seizure onset...
March 7, 2024: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
#27
JOURNAL ARTICLE
Vivek Sunil Nair, Nishita Bhosale, Vikrant Sane, Rajesh Kshirsagar, Samir Joshi, Rucha Davalbhakta
In todays era dental implant has become the dependable therapeutic treatment for the replacement of missing teeth. The success of dental implants depends not only on osteointegration of the implant but also on the surrounding hard and soft tissue. Presurgical evaluation of alveolar ridge width and height is of paramount important for implant placement. There are several methods to evaluate the alveolar ridge width and height such as ridge mapping and CBCT. This study included 30 sites from 8 patients in the age ranging from 30 to 65 years...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
#28
JOURNAL ARTICLE
Marta Araujo-Castro, Betina Biagetti, Edelmiro Menéndez Torre, Iría Novoa-Testa, Fernando Cordido, Eider Pascual Corrales, Víctor Rodríguez Berrocal, Fernando Guerrero-Pérez, Almudena Vicente, Juan Carlos Percovich, Rogelio García Centeno, Laura González, María Dolores Ollero García, Ana Irigaray Echarri, María Dolores Moure Rodríguez, Cristina Novo-Rodríguez, María Calatayud, Rocío Villar, Ignacio Bernabéu, Cristina Alvarez-Escola, Pamela Benítez Valderrama, Carmen Tenorio-Jimenéz, Pablo Abellán Galiana, Eva Venegas Moreno, Inmaculada González Molero, Pedro Iglesias, Concepción Blanco, Fernando Vidal-Ostos De Lara, Paz de Miguel, Elena López Mezquita, Felicia Hanzu, Iban Aldecoa, Cristina Lamas, Silvia Aznar, Anna Aulinas, Anna Calabrese, Paola Gracia, José María Recio-Córdova, Mariola Aviles, Diego Asensio-Wandosel, Miguel Sampedro, Ignacio Ruz-Caracuel, Rosa Camara, Miguel Paja, Carmen Fajardo-Montañana, Mónica Marazuela, Manel Puig-Domingo
PURPOSE: To evaluate differences in clinical presentation and in surgical outcomes between growth hormone-secreting pituitary adenomas (GH-PAs) and GH and prolactin co-secreting pituitary adenomas (GH&PRL-PAs). METHODS: Multicenter retrospective study of 604 patients with acromegaly submitted to pituitary surgery. Patients were classified into two groups according to serum PRL levels at diagnosis and immunohistochemistry (IHC) for PRL: a) GH&PRL-PAs when PRL levels were above the upper limit of normal and IHC for GH and PRL was positive or PRL levels were >100ng/and PRL IHC was not available (n=130) and b) GH-PAs who did not meet the previously mentioned criteria (n=474)...
March 4, 2024: Journal of Clinical Endocrinology and Metabolism
#29
JOURNAL ARTICLE
Johannes T Reiter, Freya Schulte, Tobias Bauer, Bastian David, Christoph Endler, Alexander Isaak, Fabiane Schuch, Felix Bitzer, Juri-Alexander Witt, Elke Hattingen, Ralf Deichmann, Ulrike Attenberger, Albert J Becker, Christoph Helmstaedter, Alexander Radbruch, Rainer Surges, Alon Friedman, Theodor Rüber
OBJECTIVE: Interictal blood-brain barrier dysfunction in chronic epilepsy has been demonstrated in animal models and pathological specimens. Ictal blood-brain barrier dysfunction has been shown in humans in vivo using an experimental quantitative magnetic resonance imaging (MRI) protocol. Here, we hypothesized that interictal blood-brain barrier dysfunction is also present in people with drug-resistant epilepsy. METHODS: Thirty-nine people (21 females, mean age at MRI ± SD = 30 ± 8 years) with drug-resistant epilepsy were prospectively recruited and underwent interictal T1-relaxometry before and after administration of a paramagnetic contrast agent...
March 4, 2024: Epilepsia
#30
REVIEW
Delia E Theurel Martín, Jorge L Alvarado Socarras, Edgar F Manrique Hernández, Mónica A Sandoval, Alvaro J Coronado Munoz
Oxygen therapy is essential for the survival of preterm babies and critically ill newborns; however, it has the potential to cause harm through hypoxemia or hyperoxemia. Newborns with complex congenital heart diseases (CHD) suffer from oxygen fluctuations due to the disease and its treatments, altering pre and postnatal development. The objective of this study is to evaluate the evidence for using a hypoxic mixture to decrease pulmonary over-circulation and improve systemic perfusion before surgical interventions in newborns with complex CHD that course with pulmonary over-circulation and systemic hypoperfusion...
February 2024: Curēus
#31
JOURNAL ARTICLE
Tyler Thornton, Shuda Xia, John R Zuniga, Avneesh Chhabra
Peripheral trigeminal neuropathies are assessed by MR neurography for presurgical mapping. In this clinical report, we aimed to understand the utility of MR neurography following nerve-repair procedures. We hypothesized that postoperative MR neurography assists in determining nerve integrity, and worsening MR neurography findings will corroborate poor patient outcomes. Ten patients with peripheral trigeminal neuropathy were retrospectively identified after nerve-repair procedures, with postsurgical MR neurography performed from July 2015 to September 2023...
February 29, 2024: AJNR. American Journal of Neuroradiology
#32
REVIEW
John Caraway, Matthew Ryan, Alex Yang, Nora Watson, Rhonda Allard, Michael Orestes
OBJECTIVE: Currently, the relationship between parathyroidectomy and objective neuropsychiatric outcomes are not clearly defined. The purpose of this study is to perform the first ever Meta-analysis of preoperative and postoperative PHQ-9 and GAD-7 scores in patients with primary hyperparathyroidism undergoing parathyroidectomy with the goal of identifying a specific psychometric score that could be used as an indication for surgical intervention. DATA SOURCES: A comprehensive search of the literature was performed using PubMed, Embase, PsycINFO, Web of Science, and Ovid All EBM Reviews...
February 28, 2024: Otolaryngology—Head and Neck Surgery
#33
JOURNAL ARTICLE
Kayela Arrotta, Lisa Ferguson, Nicolas Thompson, Victoria Smuk, Imad M Najm, Costin Leu, Dennis Lal, Robyn M Busch
OBJECTIVE: Demographic and disease factors are associated with cognitive deficits and postoperative cognitive declines in adults with pharmacoresistant temporal lobe epilepsy (TLE), but the role of genetic factors in cognition in TLE is not well understood. Polygenic scores (PGS) for neurological and neuropsychiatric disorders and IQ have been associated with cognition in patient and healthy populations. In this exploratory study, we examined the relationship between PGS for Alzheimer's disease (AD), depression, and IQ and cognitive outcomes in adults with TLE...
April 2024: Epilepsy & Behavior: E&B
#34
JOURNAL ARTICLE
Tatjana Traub-Weidinger, Javier Arbizu, Henryk Barthel, Ronald Boellaard, Lise Borgwardt, Matthias Brendel, Diego Cecchin, Francine Chassoux, Francesco Fraioli, Valentina Garibotto, Eric Guedj, Alexander Hammers, Ian Law, Silvia Morbelli, Nelleke Tolboom, Donatienne Van Weehaeghe, Antoine Verger, Wim Van Paesschen, Tim J von Oertzen, Pietro Zucchetta, Franck Semah
Epilepsy is one of the most frequent neurological conditions with an estimated prevalence of more than 50 million people worldwide and an annual incidence of two million. Although pharmacotherapy with anti-seizure medication (ASM) is the treatment of choice, ~30% of patients with epilepsy do not respond to ASM and become drug resistant. Focal epilepsy is the most frequent form of epilepsy. In patients with drug-resistant focal epilepsy, epilepsy surgery is a treatment option depending on the localisation of the seizure focus for seizure relief or seizure freedom with consecutive improvement in quality of life...
February 23, 2024: European Journal of Nuclear Medicine and Molecular Imaging
#35
JOURNAL ARTICLE
Gadi Miron, Paul Manuel Müller, Louisa Hohmann, Frank Oltmanns, Martin Holtkamp, Christian Meisel, Claudia Chien
OBJECTIVE: In temporal lobe epilepsy (TLE), a taxonomy classifying patients into 3 cognitive phenotypes has been adopted: minimally, focally, or multidomain cognitively impaired (CI). We examined gray matter (GM) thickness patterns of cognitive phenotypes in drug-resistant TLE and assessed potential use for predicting postsurgical cognitive outcomes. METHODS: TLE patients undergoing presurgical evaluation were categorized into cognitive phenotypes. Network edge weights and distances were calculated using type III analysis of variance F-statistics from comparisons of GM regions within each TLE cognitive phenotype and age- and sex-matched healthy participants...
February 23, 2024: Annals of Neurology
#36
JOURNAL ARTICLE
Katsuya Kobayashi, Kenneth N Taylor, Hossein Shahabi, Balu Krishnan, Anand Joshi, Michael J Mackow, Lauren Feldman, Omar Zamzam, Takfarinas Medani, Juan Bulacio, Andreas V Alexopoulos, Imad Najm, William Bingaman, Richard M Leahy, Dileep R Nair
Responsive neurostimulation is a closed-loop neuromodulation therapy for drug resistant focal epilepsy. Responsive neurostimulation electrodes are placed near ictal onset zones so as to enable detection of epileptiform activity and deliver electrical stimulation. There is no standard approach for determining the optimal placement of responsive neurostimulation electrodes. Clinicians make this determination based on presurgical tests, such as MRI, EEG, magnetoencephalography, ictal single-photon emission computed tomography and intracranial EEG...
2024: Brain communications
#37
JOURNAL ARTICLE
Á Esteban Hurtado, J Orozco Cortés, P Cárcamo Ibarra, U López González, Á Badenes Romero, M Á Navas de la Cruz, C Siscar Gelo, L Casas Calabuig, P Abreu Sánchez, T Mut Dólera, D Balaguer Muñoz, M D Reyes Ojeda, C Plancha Mansanet, E Caballero Calabuig
INTRODUCTION: Freehand SPECT can be a useful imaging technique for preoperative planning of sentinel lymph node biopsy (SLNB) as it allows localization of the sentinel node by 3D and real-time tomographic imaging and determines its depth after a few minutes of scanning. The aim of the study was to evaluate the correlation between the number of detected SNs between freehand SPECT images and lymphoscintigraphy (LS). MATERIALS AND METHODS: 100 patients with a diagnosis of invasive breast cancer and no clinical evidence of lymph node involvement prospectively underwent SLNB...
February 20, 2024: Revista española de medicina nuclear e imagen molecular
#38
JOURNAL ARTICLE
Tse-Hao Lee, Yen-Cheng Shih, Yi-Jiun Lu, Chien-Chen Chou, Cheng-Chia Lee, Hsiang-Yu Yu, Syu-Jyun Peng
PURPOSE: Reduced glucose metabolism in the hippocampus is commonly observed in cases of medial temporal lobe epilepsy (MTLE) with hippocampal sclerosis (HS). Glucose metabolism among the various hippocampal subfields has not been thoroughly investigated. PATIENTS AND METHODS: This study examined 29 patients (18 females; 15-58 years) diagnosed with HS who underwent surgery for drug-resistant epilepsy. FreeSurfer 7.1.1 was used in the processing of MRI data and 18F-FDG PET scans to derive volumetric data and the FDG SUVr in the whole hippocampus and hippocampal subfields, including the CA1, CA2-4, granule cell and molecular layer of the dentate gyrus (GC-ML-DG), and subiculum...
February 23, 2024: Clinical Nuclear Medicine
#39
JOURNAL ARTICLE
Ruxue Gong, Stephan Bickel, Gelana Tostaeva, Fred A Lado, Ashesh D Metha, Ruben I Kuzniecky, Leonardo F Bonilha, Ezequiel L Gleichgerrcht
Current preoperative evaluation of epilepsy can be challenging because of the lack of a comprehensive view of the network's dysfunctions. To demonstrate the utility of our multimodal neurophysiology and neuroimaging integration approach in the presurgical evaluation, we present a proof-of-concept for using this approach in a patient with nonlesional frontal lobe epilepsy who underwent two resective surgeries to achieve seizure control. We conducted a post-hoc investigation using four neuroimaging and neurophysiology modalities: diffusion tensor imaging, resting-state functional MRI, and stereoelectroencephalography at rest and during seizures...
February 20, 2024: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
#40
JOURNAL ARTICLE
Samuel Medina Villalon, Julia Makhalova, Victor J López-Madrona, Elodie Garnier, Jean-Michel Badier, Fabrice Bartolomei, Christian G Bénar
Stereoelectroencephalography is a powerful intracerebral EEG recording method for the presurgical evaluation of epilepsy. It consists in implanting depth electrodes in the patient's brain to record electrical activity and map the epileptogenic zone, which should be resected to render the patient seizure-free. Stereoelectroencephalography has high spatial accuracy and signal-to-noise ratio but remains limited in the coverage of the explored brain regions. Thus, the implantation might provide a suboptimal sampling of epileptogenic regions...
February 19, 2024: Scientific Reports
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