keyword
MENU ▼
Read by QxMD icon Read
search

Legg-Calvé-Perthes

keyword
https://www.readbyqxmd.com/read/29456754/management-of-osteonecrosis-of-the-femoral-head-in-children-with-sickle-cell-disease-results-of-conservative-and-operative-treatments-at-skeletal-maturity
#1
C Mallet, A Abitan, C Vidal, L Holvoet, K Mazda, A-L Simon, B Ilharreborde
Purpose: Sickle cell disease (SCD) is the most common cause of femoral head osteonecrosis (ONFH) during childhood with an overall prevalence of 10%. In children, spontaneous revascularization can occur, as in Legg-Calve-Perthes disease. Consequently, the aim of treatment is to restore proper hip containment to prevent joint arthritis. This is the first study reporting long-term results at skeletal maturity of non-operative and surgical treatments for ONFH in SCD children. Methods: All children with ONFH due to SCD were retrospectively reviewed...
February 1, 2018: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/29440159/multicentre-study-on-capsular-closure-versus-non-capsular-closure-during-hip-arthroscopy-in-danish-patients-with-femoroacetabular-impingement-fai-protocol-for-a-randomised-controlled-trial
#2
Christian Dippmann, Otto Kraemer, Bent Lund, Michael Krogsgaard, Per Hölmich, Martin Lind, Karen Briggs, Marc Philippon, Bjarne Mygind-Klavsen
INTRODUCTION: Hip arthroscopy has become a standard procedure in the treatment of hip joint pain not related to osteoarthritis or dysplasia in the young and active patient. There has been increasing focus on the contribution of the hip capsule to function and on stability following hip arthroscopy. It has been suggested that capsular closure after hip arthroscopy may prevent microinstability and macroinstability of the hip joint and reduce revision rate. However, it remains unknown whether capsular closure should be performed as a standard procedure when performing hip arthroscopies, especially in patients without additional risk factors for instability such as hypermobility or dysplasia of the hip...
February 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29437587/new-insights-into-the-biomechanics-of-legg-calv%C3%A3-perthes-disease-the-role-of-epiphyseal-skeletal-immaturity-in-vascular-obstruction
#3
M Pinheiro, C A Dobson, D Perry, M J Fagan
OBJECTIVES: Legg-Calvé-Perthes' disease (LCP) is an idiopathic osteonecrosis of the femoral head that is most common in children between four and eight years old. The factors that lead to the onset of LCP are still unclear; however, it is believed that interruption of the blood supply to the developing epiphysis is an important factor in the development of the condition. METHODS: Finite element analysis modelling of the blood supply to the juvenile epiphysis was investigated to understand under which circumstances the blood vessels supplying the femoral epiphysis could become obstructed...
February 2018: Bone & Joint Research
https://www.readbyqxmd.com/read/29419321/the-potential-role-of-variations-in-juvenile-hip-geometry-on-the-development-of-legg-calv%C3%A3-perthes-disease-a-biomechanical-investigation
#4
Manuel da Silva Pinheiro, Catherine Dobson, Nicholas M Clarke, Michael Fagan
Legg-Calvé-Perthes disease (LCP) is one of the most poorly understood diseases in paediatric orthopaedics. One common trait of LCP is the marked morphological difference between healthy and pathological hips, early deviations of which (i.e. prior to disease onset) have been suggested to lead to the overload and collapse of the epiphysis. Here, the impact of common variations in geometry is investigated with a finite element model of a juvenile femur under single leg standing and landing. Here, the impact of typical variations in geometry is investigated with a finite element model of a juvenile femur under single leg standing and landing...
February 8, 2018: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/29387248/downregulated-sox9-mediated-by-mir-206-promoted-cell-apoptosis-in-legg-calv%C3%A3-perthes-disease
#5
Junzhong Luo, Jiuhui Han, Yazhou Li, Yuchang Liu
Legg-Calvé-Perthes disease (LCPD) commonly onsets in adolescents, and threatens their health. However, the potential mechanism underlying LCPD remains unclear. MicroRNA (miR)-206 and SRY-box 9 (SOX9) serve an important role in chondrocytes; however, their role in LCPD remains ambiguous. In the present study, whether miR-206 and SOX9 mediated cell apoptosis in dexamethasone (DEX)-induced LCPD was investigated. The chondrocytes of the LCPD and normal control group were isolated from clinical tissues. Reverse transcription-quantitative polymerase chain reaction was used to evaluate the expression of miR-206 and SOX9 mRNA...
January 2018: Oncology Letters
https://www.readbyqxmd.com/read/29219855/determining-hinge-abduction-in-legg-calv%C3%A3-perthes-disease-can-we-reliably-make-the-diagnosis
#6
Benjamin J Shore, Patricia E Miller, Ira Zaltz, Perry L Schoenecker, Wudbhav N Sankar
BACKGROUND: Although hinge abduction is recognized as an important finding in children with Legg-Calvé-Perthes disease, variable diagnostic criteria exist. The purpose of this study was (1) to test the interobserver and intraobserver agreement of the current definition of hinge abduction and (2) to develop consensus regarding key diagnostic features that could be used to improve our diagnostic criteria. METHODS: Four orthopaedic surgeons with subspecialty pediatric hip interest independently assessed 30 randomly ordered cases of Legg-Calvé-Perthes disease...
December 6, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29201291/long-term-results-of-modified-salter-innominate-osteotomy-for-legg-calv%C3%A3-perthes-disease
#7
Kyung Soon Park, Kyu Jin Cho, Hong Yeol Yang, Kamolhuja Eshnazarovich Eshnazarov, Taek Rim Yoon
Background: In a previous study, we reported clinical and radiographic results of our modified Salter innominate osteotomy technique in 16 hips affected by Legg-Calvé-Perthes disease (LCPD) with an average follow-up of 31.8 months. In this study, we present the long-term results of the osteotomy in LCPD patients followed until physeal closure. Methods: Thirty hips of 29 patients were followed until skeletal maturation after modified Salter innominate osteotomy...
December 2017: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/29192726/outcomes-in-patients-with-late-sequelae-healed-stage-of-legg-calv%C3%A3-perthes-disease-undergoing-arthroscopic-treatment-retrospective-case-series
#8
Woo-Yong Lee, Deuk-Soo Hwang, Yong-Chan Ha, Pil-Sung Kim, Long Zheng
INTRODUCTION: The residual hip deformities after Legg-Calvé-Perthes disease (LCPD) cause mechanical symptoms and are associated with a pathomechanical environment that can feature femoroacetabular impingement (FAI).The aim of this study is to evaluate the clinical and radiological outcomes in residual or healed LCPD after arthroscopic treatment. PATIENTS AND METHODS: We retrospectively reviewed patients with LCPD amongst patients with FAI who underwent arthroscopic treatment between January 2009 and June 2013...
December 1, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29181581/evaluation-of-femoral-head-viability-via-bone-scintigraphy-in-the-postoperative-pediatric-patient
#9
Ashishkumar K Parikh, Eleby R Washington, Adam J Bobbey, Stephanie E Spottswood
BACKGROUND: Evaluating postoperative patients with hardware is challenging following surgical intervention for hip maladies such as femoral neck fractures and slipped capital femoral epiphysis (SCFE). These children are at increased risk of developing avascular necrosis, and imaging may be requested to confirm or exclude this diagnosis. Children with Legg-Calvé-Perthes disease can be monitored for restoration of blood flow to the capital femoral epiphysis to guide management and help with prognosis...
November 27, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/29157629/mri-appearance-in-the-early-stage-of-legg-calv%C3%A3-perthes-disease-to-predict-lateral-pillar-classification-a-retrospective-analysis-of-the-labral-horizontalization
#10
Yasuhiro Shirai, Kenjiro Wakabayashi, Ikuo Wada, Yoshiaki Tsuboi, Myongsu Ha, Takanobu Otsuka
BACKGROUND: The Herring lateral pillar classification is widely used for the classification of Legg-Calvé-Perthes disease, but is not applied at the early stage of Legg-Calvé-Perthes disease because it is typically applied at the late fragmentation stage. The purpose of this study was to investigate the correlation between the early appearance on magnetic resonance imaging of the acetabular labrum and lateral pillar involvement in Legg-Calvé-Perthes disease. METHODS: Non-contrast magnetic resonance images of 26 hips in 25 children with early-stage Legg-Calvé-Perthes disease were retrospectively reviewed...
November 17, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29155310/legg-calv%C3%A3-perthes-disease
#11
REVIEW
J Leroux, S Abu Amara, J Lechevallier
Current knowledge of the causes and risk factors of Legg-Calvé-Perthesdisease (LCPD) does not allow effective preventive strategies. The outcome in adulthood is usually good. Hip osteoarthritis rarely develops before 50 years of age. The risk of osteoarthrosis depends chiefly on the final degree of joint incongruence. Age at onset and the lateral pillar classification are the two main outcome predictors and serve to guide the surgical indications based on the studies by Herring's group. Non-operative treatment is not effective...
November 16, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29027515/-a-boy-with-a-white-striped-knee-on-a-radiograph
#12
M G Mentink, R J P Weber, F H Jansen
A 10-year-old boy presented at the radiology department with pain in the right knee. Radiographs of the knee revealed dens metaphyseal bands and subchondral epiphyseal sclerosis as a result of periodic bisphosphonate administration for the treatment of Legg-Calvé-Perthes disease three years ago.
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29027185/advanced-containment-methods-for-legg-calv%C3%A3-perthes-disease-triple-pelvic-osteotomy-versus-chiari-osteotomy
#13
Olivier Rosello, Federico Solla, Ioana Oborocianu, Edouard Chau, Tony ElHayek, Jean-Luc Clement, Virginie Rampal
INTRODUCTION: The goal of intervention in Legg-Calvé-Perthes disease (LCPD) is to prevent femoral head deformation by containing the head within the acetabulum. Currently, surgical containment methods are the mainstay of treatment, and pelvic osteotomies have been shown to be successful. They include triple pelvic osteotomy (TPO), Salter osteotomy, Chiari osteotomy and shelf procedure. The purpose of this study was to compare clinical and radiologic results for Chiari osteotomy and TPO in LCPD...
October 11, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29027115/correlation-between-mri-and-hip-arthroscopy-in-children-with-legg-calve-perthes-disease
#14
V Tiwari, S Gamanagatti, R Mittal, H Nag, S A Khan
BACKGROUND: Most of the information available about Legg-Calve-Perthes disease (LCPD) at present is gained through imaging modalities including plain radiographs and magnetic resonance imaging (MRI). But the accuracy of MRI in this disease and its predictive value to reveal various intra-articular pathologies is not known. We correlated the findings of MRI with those seen on hip arthroscopy in children with active stage of LCPD. METHODS: We conducted a prospective observational study in which MRI findings were correlated with corresponding findings on hip arthroscopy in a cohort of 25 patients of active LCPD below 12 years of age...
October 12, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28982606/clinical-outcomes-of-conservative-treatment-with-a-non-weight-bearing-abduction-brace-for-legg-calv%C3%A3-perthes-disease
#15
Miho Iwamoto, Yasuharu Nakashima, Tomoyuki Nakamura, Yusuke Kohno, Ryosuke Yamaguchi, Kazuyuki Takamura
BACKGROUND: Treatment with a brace is the first choice as conservative treatment via the containment method for Legg-Calvé-Perthes disease (LCPD). The purpose of this study is to evaluate clinical outcomes and influential factors of conservative treatment with the non-weight-bearing abduction brace for LCPD. METHODS: One hundred thirty hips in 130 patients were examined in this study. The mean age at onset was 7.0 years (3.3-12.4 years) and the mean follow-up period was 8...
October 2, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28956304/is-vegf-under-expressed-in-indian-children-with-perthes-disease
#16
V Tiwari, R R Poudel, S A Khan, S Mehra, S S Chauhan, A Raje
BACKGROUND: The role of vascular endothelial growth factor (VEGF) after ischaemic necrosis of the femoral head in Legg-Calve-Perthes disease (LCPD) has not been adequately studied in humans, especially in Indian population. Therefore, we aimed to evaluate the serum levels of VEGF-A in Indian children with various stages of LCPD and compare them with those of an age- and sex-matched control group of healthy children. METHODS: In this case-control study, we enrolled 42 children (below 14 years age) suffering from LCPD and 21 age- and sex-matched healthy controls...
September 27, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28937786/prevalence-of-femoral-and-acetabular-version-abnormalities-in-patients-with-symptomatic-hip-disease-a-controlled-study-of-538-hips
#17
Till D Lerch, Inga A S Todorski, Simon D Steppacher, Florian Schmaranzer, Stefan F Werlen, Klaus A Siebenrock, Moritz Tannast
BACKGROUND: Variations in femoral and acetabular version are becoming increasingly recognized as contributing factors to the development of hip pain in patients with femoroacetabular impingement (FAI) and hip dysplasia. It is still unknown what the true prevalence of these rotational abnormalities is in this patient population. PURPOSE: To determine (1) the prevalence of femoral version abnormalities in symptomatic hips with FAI and hip dysplasia, (2) the prevalence of combined abnormalities of femoral and acetabular version in these patients, and (3) which specific hip morphologies are associated with abnormalities of femoral version...
January 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28914956/ischemic-femoral-head-osteonecrosis-in-a-piglet-model-causes-three-dimensional-decrease-in-acetabular-coverage
#18
Vidyadhar V Upasani, Megan E Jeffords, Christine L Farnsworth, David Padilla, Nick Lopreiato, Olumide O Aruwajoye, Harry K W Kim
Legg-Calve-Perthes disease (LCPD) is a childhood form of ischemic osteonecrosis marked by development of severe femoral head deformity and premature osteoarthritis. The pathogenesis of femoral head deformity has been studied extensively using a piglet model of ischemic osteonecrosis, however accompanying acetabular changes have not been investigated. The purpose of this study was to determine if acetabular changes accompany femoral head deformity in a well-established piglet model of LCPD and to define the acetabular changes using 3 dimensional computed tomography (3-D CT) and modeling...
September 15, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28870190/monobloc-implants-in-cementless-total-hip-arthroplasty-in-patients-with-legg-calve-perthes-disease-a-long-term-follow-up
#19
Ze-Yu Luo, Hao-Yang Wang, Duan Wang, Hui Pan, Fu-Xing Pei, Zong-Ke Zhou
BACKGROUND: The purpose of this study was to evaluate 10-year outcomes in cementless monobloc total hip arthroplasty (THA) in a group of hips with Legg-Calve-Perthes disease (LCPD). METHODS: We reviewed 71 patients (88 hips) who underwent cementless THA with a diagnosis of LCPD from 2003 to 2009. From the total of 71 patients, 34 men and 37 women with an average age of 49.94 years were included. The mean follow-up period was 10 years. RESULTS: The mean Harris Hip Score improved significantly from 46...
September 5, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28767613/effect-of-greater-trochanteric-epiphysiodesis-after-femoral-varus-osteotomy-for-lateral-pillar-classification-b-and-b-c-border-legg-calv%C3%A3-perthes-disease-a-retrospective-observational-study
#20
Keun-Sang Kwon, Sung Il Wang, Ju-Hyung Lee, Young Jae Moon, Jung Ryul Kim
This is a retrospective observational study. Greater trochanteric epiphysiodesis (GTE) has been recommended to prevent Trendelenburg gait and limitation of the hip joint motion due to trochanteric overgrowth after femoral varus osteotomy (FVO) in Legg-Calvé-Perthes disease (LCPD). However, capital femoral physeal arrest frequently occurs in patients with severe disease (lateral pillar C), so GTE might not be as effective in these patients. The aim of this study was to compare trochanteric growth inhibition due to GTE after FVO between 2 age groups (<8 or >8 years) in patients with lateral pillar B and B/C border LCPD and evaluate the effectiveness of GTE compared with the normal, unaffected hip...
August 2017: Medicine (Baltimore)
keyword
keyword
63070
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"