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https://www.readbyqxmd.com/read/28915209/the-expanded-use-of-auto-augmentation-techniques-in-oncoplastic-breast-surgery
#1
Albert Losken, Alexandra M Hart, James Walter Dutton, Justine S Broecker, Toncred M Styblo, Grant W Carlson
BACKGROUND: Auto-augmentation techniques have been applied to oncoplastic reductions to assist with filling larger, more remote defects and women with smaller breasts. The purpose of this report is to describe the use of auto-augmentation techniques in OR and compare the results with traditional OR. METHODS: We queried a prospectively maintained database of all women who underwent partial mastectomy and OR between 1994 and October 2015. The auto-augmentation techniques were defined as 1) extended primary nipple auto-augmentation pedicle, and 2) primary nipple pedicle and secondary auto-augmentation pedicle...
September 13, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28912071/sentinel-node-biopsy-after-primary-chemotherapy-in-ct2-n0-1-breast-cancer-patients-long-term-results-of-a-retrospective-study
#2
G Martelli, R Miceli, S Folli, E Guzzetti, C Chifu, I Maugeri, C Ferranti, G Bianchi, G Capri, M L Carcangiu, B Paolini, R Agresti, C Ferraris, D Piromalli, M Greco
BACKGROUND: It is controversial whether sentinel node biopsy (SNB) is adequate in breast cancer patients who become cN0 after primary chemotherapy. To address this we retrospectively compared outcomes in T2 cases given primary chemotherapy, comparing those given axillary dissection (AD) with those given SNB but no AD if sentinel nodes were clinically negative post-chemotherapy. METHODS: We examined overall survival (OS), disease-free survival (DFS), and axillary failure in 317 consecutive cT2 cN0/1 patients given primary chemotherapy followed by quadrantectomy/mastectomy, between January 2002 and December 2007...
August 10, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28911335/mammary-phyllodes-tumor-with-six-episodes-of-a-relapse-a-case-report
#3
Nozomi Iimori, Shinichiro Kashiwagi, Tetsuro Ishikawa, Hidemi Kawajiri, Tsutomu Takashima, Masahiko Ohsawa, Kosei Hirakawa, Masaichi Ohira
BACKGROUND: Phyllodes tumor is a rare breast mass. Most phyllodes tumors are benign, but occasionally some show malignancy. Even if the tumors are benign, they can easily show recurrence. CASE PRESENTATION: We report a case of a 48-year-old Asian woman, who had previously undergone a tumorectomy of her left breast 12 years before, with a pathological diagnosis of fibroadenoma. Five years after the initial tumorectomy, the patient presented with an abnormally enlarged left breast...
September 15, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28894694/evaluation-of-partial-breast-reirradiation-with-intraoperative-radiotherapy-after-prior-thoracic-radiation-a-single-institution-report-of-outcomes-and-toxicity
#4
Christine Chin, Priya Jadeja, Bret Taback, David P Horowitz, Sheldon M Feldman, Richard Ha, Eileen P Connolly
INTRODUCTION: Mastectomy is the current standard of care for ipsilateral breast tumor recurrences after prior whole breast irradiation (WBI). We report our single-institution experience with breast-conserving surgery (BCS) followed by intraoperative radiotherapy (IORT) as an alternative to salvage mastectomy for new or recurrent breast cancers that develop in the setting of prior thoracic radiation. METHODS: We performed an IRB-approved retrospective review of patients treated with breast IORT between September 2013 and November 2016...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28893060/clinical-significance-of-the-lymph-node-ratio-in-n1-breast-cancer
#5
Jaeho Kim, Jin Hee Kim, Ok Bae Kim, Young Kee Oh, Seung Gyu Park
Purpose: The purpose of this study was to evaluate the prognostic value of the lymph node ratio (LNR), which was defined as the proportion of involved nodes of all dissected nodes, in pN1 breast cancer. Materials and Methods: We retrospectively analyzed the clinical data of patients with pN1 breast cancer (N = 144) treated at Keimyung University Dongsan Medical Center, Daegu, Korea between 2001 and 2010. The median age was 46 years (range, 27 to 66 years). The LNR was 0...
September 15, 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/28871582/pyoderma-gangrenosum-after-breast-mastectomy-and-primary-rectus-abdominis-flap-reconstruction
#6
Yasuhiro Suzuki, Kozue Yokoyama, Mayako Terao, Toru Morioka, Banri Tsuda, Naoki Niikura, Takuho Okamura, Eri Yamada, Kotaro Imagawa, Tadashi Akamatsu, Yutaka Tokuda, Nobue Kumaki
Pyoderma gangrenosum is an intractable disease of unknown cause involving recurrent ulcerative lesions on the skin, and may accompany ulcerative colitis, rheumatoid arthritis, leukemia, systemic lupus erythematosus, and other conditions. Here, we report a rare case of pyoderma gangrenosum in the thoracic abdomen following post-mastectomy reconstructive surgery. A 39-year-old presented at the hospital with a complaint of left papilla erosion. Skin biopsy at the site revealed invasive skin cancer, with Paget-like progression in the cancerous nipple and suspected malignancy of skin appendages...
September 20, 2017: Tokai Journal of Experimental and Clinical Medicine
https://www.readbyqxmd.com/read/28868019/cystoid-macular-edema-during-treatment-with-paclitaxel-and-bevacizumab-in-a-patient-with-metastatic-breast-cancer-a-case-report-and-literature-review
#7
Takamichi Yokoe, Ippei Fukada, Kokoro Kobayashi, Tomoko Shibayama, Yumi Miyagi, Atsushi Yoshida, Takuji Iwase, Shinji Ohno, Yoshinori Ito
We present a case of a metastatic breast cancer patient with cystoid macular edema (CME) occurring during treatment with paclitaxel and bevacizumab. She had a history of neoadjuvant chemotherapy and partial mastectomy plus axillary lymph node dissection for stage IIB left-breast cancer. Twenty-four months later, she was diagnosed with multiple bone metastases and underwent chemotherapy with paclitaxel and bevacizumab. Thirty-three months after the initiation of the chemotherapy, she noticed bilateral blurred vision...
May 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28861373/staged-approach-to-partial-breast-reconstruction-to-avoid-mastectomy-in-women-with-breast-cancer
#8
Pankaj G Roy, Alexandra A Tenovici
BACKGROUND: The lateral chest wall perforator flaps (CWPF) offer an excellent option for partial breast reconstruction (PBR) in women undergoing breast conservation surgery (BCS) for laterally placed tumours in small to moderate non-ptotic breasts. METHODS: A total of 20 patients underwent PBR with lateral CWPF over the last 4 years, as two-stage approach. This approach was undertaken for patients with high tumour to breast ratio (>30% predicted resection) in an attempt to avoid mastectomy...
August 2017: Gland Surgery
https://www.readbyqxmd.com/read/28846943/breast-metastasis-nine-years-after-nephrectomy-for-renal-cell-carcinoma-a-case-report
#9
Takayuki Ishigaki, Satoki Kinoshita, Naoko Shimada, Ryo Miyake, Masaaki Suzuki, Hiroshi Takeyama
INTRODUCTION: The breast is a rare site for metastatic disease. We report a rare case of breast metastasis 9 years after nephrectomy for renal cell carcinoma (RCC) and include a review of the relevant literature. PRESENTATION OF CASE: An 82-year-old woman who developed an RCC underwent left nephrectomy in 2005. In October 2014, computed tomography (CT) revealed a mass of approximately 1cm in the lateral portion of the right breast. Breast ultrasonography (US) revealed a well-circumscribed, hypoechoic mass at the same site...
August 18, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28843370/a-phase-ii-study-of-preoperative-capecitabine-and-concomitant-radiation-in-women-with-advanced-breast-cancer
#10
Wendy A Woodward, Penny Fang, Lisa Arriaga, Hui Gao, Evan N Cohen, James M Reuben, Vicente Valero, Huong Le-Petross, Lavinia P Middleton, Gildy V Babiera, Eric A Strom, Welela Tereffe, Karen Hoffman, Benjamin D Smith, Thomas A Buchholz, George H Perkins
PURPOSE: To examine the response rate of gross chemo-refractory breast cancer treated with concurrent capecitabine (CAP) and radiation therapy in a prospective Phase II study. METHODS AND MATERIALS: Breast cancer patients with inoperable disease after chemotherapy, residual nodal disease after definitive surgical resection, unresectable chest wall or nodal recurrence after a prior mastectomy, or oligometastatic disease were eligible. Response by RECIST criteria was assessed after 45 Gy...
May 3, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28832176/-reactive-lymphoid-hyperplasia-of-the-liver
#11
B Dobiašová, M Zvaríková, K Petráková
Here, we present the case of a 50-year-old woman diagnosed with stage I hormone-dependent breast cancer. The patient underwent partial mastectomy followed by adjuvant radiotherapy and hormone treatment with tamoxifen. Three years later, she presented with a solitary liver lesion on MRI, which was highly suspicious of malignancy. However, several fine needle biopsies were performed, and histopathological examination revealed no signs of neoplasia. As a result of these alarming discrepancies, the multidisciplinary board recommended a diag-nostic laparotomy, which yielded a finding consistent with reactive lymphoid hyperplasia, a pseudolymphoma of the liver, on a background of incipient steatohepatitis...
2017: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/28766199/a-patient-specific-3d-printed-form-accurately-transfers-supine-mri-derived-tumor-localization-information-to-guide-breast-conserving-surgery
#12
Richard J Barth, Venkataramanan Krishnaswamy, Keith D Paulsen, Timothy B Rooney, Wendy A Wells, Elizabeth Rizzo, Christina V Angeles, Jonathan D Marotti, Rebecca A Zuurbier, Candice C Black
BACKGROUND: Wire-localized excision of nonpalpable breast cancer is imprecise, resulting in positive margins 25-30% of the time. METHODS: Patients underwent preoperative supine magnetic resonance imaging (MRI). A radiologist outlined the tumor edges on consecutive images, creating a three-dimensional (3D) view of its location. Using 3D printing, a bra-like plastic form (the Breast Cancer Locator [BCL]) was fabricated, with features that allowed a surgeon to (1) mark the edges of the tumor on the breast surface; (2) inject blue dye into the breast 1 cm from the tumor edges; and (3) place a wire in the tumor at the time of surgery...
August 1, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28740793/donor-site-complications-and-remnant-of-rectus-abdominis-muscle-status-after-transverse-rectus-abdominis-myocutaneous-flap-reconstruction
#13
Prakasit Chirappapha, Noppadol Trikunagonvong, Duangkamon Prapruttam, Sasiprapa Rongthong, Panuwat Lertsithichai, Thongchai Sukarayothin, Monchai Leesombatpaiboon, Rujira Panawattanakul, Panya Thaweepworadej
BACKGROUND: Transverse rectus abdominis myocutaneous (TRAM) flap reconstruction after mastectomy in breast cancer patients has become one of the milestones in breast reconstruction. There are several techniques that have been used in an attempt to minimize untoward complications. We present the whole muscle with partial sheath-sparing technique that focuses on the anatomy of arcuate line and the closure of the anterior abdominal wall techniques with mesh and determine factors associated with its complications and outcomes...
June 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28739621/lipoma-of-superior-vena-cava-a-rare-occurrence
#14
Ahsan Wahab, Siddique Chaudhary, Ahmad Munir, Susan Jane Smith
Most benign primary cardiac tumours are myxomas; non-myxomatous tumours are less common but comprise a wide variety. Cardiac lipoma is a rare non-myxomatous variety. A 70-year-old Caucasian woman with right breast cancer status postpartial mastectomy underwent surveillance MRI of the breast and was found to have a possible right atrial (RA) mass. She also reported frequent headaches and palpitations. She underwent a transoesophageal echocardiogram which showed a 2.6×1.6×1.6 cm echogenic mass at the superior vena cava (SVC) and RA junction...
July 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28738939/can-tumor-biology-predict-occult-multifocal-disease-in-breast-cancer-patients
#15
RANDOMIZED CONTROLLED TRIAL
Anees B Chagpar, Ali F Cicek, Malini Harigopal
The SHAVE trial is a prospective trial in which 235 women with stage 0 to 3 disease undergoing partial mastectomy were randomized intraoperatively to either have cavity shave`s (CSMs) taken at the time of initial surgery or not. In this study, 9 of the 76 patients (11.8%) with initially negative margins randomized to the "shave" group had occult cancers found in the CSM. Seven of these patients had sufficient primary tumor tissue available for further analysis. These patients were age and stage matched in a 1:2 ratio to other patients in the trial who had no further disease found in their CSM...
July 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28732040/perceptions-of-arab-men-regarding-female-breast-cancer-screening-examinations-findings-from-a-middle-east-study
#16
Tam Truong Donnelly, Al-Hareth Al-Khater, Salha Bujassoum Al-Bader, Mohamed Ghaith Al-Kuwari, Mariam Ali Abdul Malik, Nabila Al-Meer, Rajvir Singh
OBJECTIVES: In the Middle East, Qatar in particular, the incidence of breast cancer has substantially increased in recent years, and is expected to double by 2030. This diagnosis also occurs at a later stage in the disease. Early detection along with proper treatment reduces radical mastectomy and mortality rates, yet only one-third of Arab women in Qatar participate in breast cancer screening (BCS) activities of any sort. Many women in the conservative Qatari society rely on male family members for support and protection...
2017: PloS One
https://www.readbyqxmd.com/read/28710505/application-of-human-acellular-breast-dermal-matrix-abdm-in-implant-based-breast-reconstruction-an-experimental-study
#17
Nahid Nafisi, Mohammad Esmaeil Akbari, Fatemeh Mahjoub, Mohammad Javad Mohseni, Shabnam Sabetkish, Reza Khorramirouz, Mona Tehrani, Abdol-Mohammad Kajbafzadeh
BACKGROUND: The use of acellular dermal matrices (ABDM) has become more common for breast reconstruction to improve postoperative outcomes. We evaluated the efficacy of breast reconstruction by the application of human ABDM in a sheep model. METHODS: The sheep in group I (GI) (N = 4) underwent the following procedures on the right side: (1) breast reconstruction using human ABDM after total mastectomy, (2) human ABDM under the skin, near the breast area and on the left side, (3) fat injection and human ABDM after partial mastectomy, and (4) replacement of ABDM in the abdominal wall far from the breast...
July 14, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28698832/acute-inflammatory-response-during-neoadjuvant-chemotherapy-for-locally-advanced-breast-cancer-a-case-report
#18
Xiaolan Feng, Tanya Berrang, John Paul McGhie, Peter Watson, R Petter Tonseth, Pauline T Truong
We report on a 56-year-old Caucasian female, diagnosed with locally advanced, hormone-receptor-positive, and human epidermal growth factor receptor 2 (HER2)-positive cancer of the left breast. The patient received neoadjuvant chemotherapy with adriamycin/cyclophosphamide (AC) followed by docetaxel/trastuzumab. A partial clinical and radiographical response was documented after four cycles of AC. Approximately one week after the first cycle of docetaxel and trastuzumab, the patient presented with diffuse edema, erythema, and induration involving the entire left breast...
June 10, 2017: Curēus
https://www.readbyqxmd.com/read/28697858/accelerated-partial-breast-irradiation-for-elderly-women-with-early-breast-cancer-a-compromise-between-whole-breast-irradiation-and-omission-of-radiotherapy
#19
Shakeel Sumodhee, Johan Levy, Emmanuel Chamorey, Daniel Lam Cham Kee, Marie-Eve Chand, Mathieu Gautier, Isabelle Peyrottes, Emmanuel Barranger, Jean-Michel Hannoun-Levi
PURPOSE: Regarding adjuvant radiation therapy making decision for elderly women, Albert (2013) published a nomogram predicting the mastectomy-free survival (MFS) rate with or without adjuvant irradiation. Based on this approach, we proposed to investigate the use of accelerated partial breast irradiation (APBI) vs. whole breast irradiation (WBI) or endocrine therapy alone in elderly low-risk breast cancer patients. METHODS AND MATERIALS: For each elderly woman treated by conserving surgery and APBI (multicatheter interstitial high-dose-rate brachytherapy), 5- and 10-year MFS rates were calculated...
July 8, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28690051/nipple-sparing-mastectomy-for-breast-cancer-is-associated-with-high-patient-satisfaction-and-safe-oncological-outcomes
#20
V Mesdag, C Régis, E Tresch, M-P Chauvet, L Boulanger, P Collinet, S Giard
BACKGROUND: The preservation of the nipple areolar complex (NAC) for cancer treatment is still a matter of debate because of suspected increase of local recurrence and surgery-specific complications. The aim of the study was to investigate both the relapse risk associated with nipple sparing mastectomy (NSM) for breast cancer and women's satisfaction with preservation of the NAC. METHODS: We included retrospectively all patients who had skin-sparing mastectomy (SSM) or NSM from 2007 to 2012 for breast cancer or ductal carcinoma in situ (DCIS)...
July 8, 2017: Journal of gynecology obstetrics and human reproduction
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