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https://www.readbyqxmd.com/read/28213790/optical-see-through-cancer-vision-goggles-enable-direct-patient-visualization-and-real-time-fluorescence-guided-oncologic-surgery
#1
Suman B Mondal, Shengkui Gao, Nan Zhu, LeMoyne Habimana-Griffin, Walter J Akers, Rongguang Liang, Viktor Gruev, Julie Margenthaler, Samuel Achilefu
BACKGROUND: The inability to visualize the patient and surgical site directly, limits the use of current near infrared fluorescence-guided surgery systems for real-time sentinel lymph node biopsy and tumor margin assessment. METHODS: We evaluated an optical see-through goggle augmented imaging and navigation system (GAINS) for near-infrared, fluorescence-guided surgery. Tumor-bearing mice injected with a near infrared cancer-targeting agent underwent fluorescence-guided, tumor resection...
February 17, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28203501/partial-breast-reconstruction-with-goldilocks-technique-after-excision-of-giant-fibroadenoma-a-case-report
#2
Ryan P Ter Louw, Sara B Bruce, Maurice Y Nahabedian
Giant juvenile fibroadenomas are relatively rare, accounting for less than 1% fibroadenomas. Large breast tumors create significant asymmetry and provide unique reconstructive challenges after removal. In this case, we describe a 21-year-old female with delayed presentation of a giant fibroadenoma of the right breast. This represents an unusual presentation of benign breast disease requiring reduction of the skin envelope, extensive glandular resection, lower pole reconstruction, and free nipple grafting to achieve symmetry with the opposite breast...
January 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28182268/racial-disparities-in-brca-testing-and-cancer-risk-management-across-a-population-based-sample-of-young-breast-cancer-survivors
#3
Deborah Cragun, Anne Weidner, Courtney Lewis, Devon Bonner, Jongphil Kim, Susan T Vadaparampil, Tuya Pal
BACKGROUND: Breast cancer (BC) disparities may widen with genomic advances. The authors compared non-Hispanic white (NHW), black, and Hispanic BC survivors for 1) cancer risk-management practices among BRCA carriers and 2) provider discussion and receipt of genetic testing. METHODS: A population-based sample of NHW, black, and Hispanic women who had been diagnosed with invasive BC at age 50 years or younger from 2009 to 2012 were recruited through the state cancer registry...
February 9, 2017: Cancer
https://www.readbyqxmd.com/read/28169489/psychological-and-endocrine-factors-and-pain-after-mastectomy
#4
D Nishimura, S Kosugi, Y Onishi, N Ihara, K Wakaizumi, H Nagata, T Yamada, T Suzuki, S Hashiguchi, H Morisaki
BACKGROUND: This prospective study was designed to examine the associations of demographic, clinical, psychological and neuroendocrine factors with acute and chronic post-operative pain following partial mastectomy. METHODS: Sixty-four female patients scheduled for partial mastectomy were enrolled. Pre-operative anxiety/depression was assessed, using the Hospital Anxiety and Depression Scale (HADS). Pre-operative 24-h urinary cortisol levels were measured 2 days before surgery...
February 7, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28162480/-248-acute-and-subacute-postoperative-pain-after-partial-and-total-mastectomy-association-with-prospectively-assessed-psychosocial-and-psychophysical-variables
#5
K Schreiber, N Zinboonyahgoon, M Cornelius, R Edwards
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28133343/-two-cases-of-stromal-sarcoma-of-the-breast
#6
Hiroyuki Takahashi, Satoshi Inaba, Hidehiko Yabuki
Stromal sarcoma of the breast is a very rare disease accounting for 0.03%of primary breast malignant tumors. From 1995 to 2014, 384 patients with primary breast malignant tumors underwent resection at our institution, of which 2 cases(0.5%) were stromal sarcoma of the breast. Case 1: A woman aged in her 50's presented with a painful lump spanning the right breast identified 7-8 months previously by palpation. The patient first visited the outpatient department at our hospital when the lump gradually increased in size and bleeding from the breast was observed...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133050/-a-case-of-squamous-cell-carcinoma-of-the-right-breast
#7
Ryouichi Tomita, Shigeru Fujisaki, Takeo Azuhata, Yuko Takamoto, Kenichi Sakurai, Kayomi Kitada
Squamous cell carcinoma(SCC)of the breast is rare and its clinicopathological features have not been fully elucidated. We report a patient with SCC of the right breast who underwent surgical resection. A 51-year-old woman was admitted to our hospital because of a right breast tumor. A round tumor with an irregular surface measuring about 3.0×2.5 cm was palpable in the ACarea of the right breast. No abnormal data were observed on laboratory examination, including tumor markers such as carcinoembryonic antigen(CEA), cancer antigen 15-3(CA15-3), breast cancer antigen 225(BCA225), and SCC antigen...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28115955/clinical-outcomes-toxicity-and-cosmesis-in-breast-cancer-patients-with-close-skin-spacing-treated-with-accelerated-partial-breast-irradiation-apbi-using-multi-lumen-catheter-applicators
#8
Mani Akhtari, Mirna Abboud, Sean Szeja, Ramiro Pino, Gary D Lewis, Barbara L Bass, Darlene M Miltenburg, E Brian Butler, Bin S Teh
PURPOSE: Accelerated partial breast irradiation (APBI) using a single-lumen device is associated with better cosmetic outcomes if the spacing between the applicator and skin is > 7 mm. However, there are no reports addressing the late toxicity and clinical outcomes in patients treated with single-entry multi-lumen/catheter applicators who had close skin spacing (7 mm or less). We undertook this study to report clinical outcome, acute and late toxicity as well as cosmesis of early stage breast cancer patients with close skin spacing treated with APBI using multi-lumen or multi-catheter devices...
December 2016: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/28103951/multiple-metastatic-malignant-phyllodes-tumor-of-the-breast-with-tonsillar-metastasis-a-case-report
#9
Tomohiro Sera, Shinichiro Kashiwagi, Tsutomu Takashima, Yuka Asano, Wataru Goto, Nozomi Iimori, Satoru Noda, Naoyoshi Onoda, Masahiko Ohsawa, Kosei Hirakawa, Masaichi Ohira
BACKGROUND: Tonsillar metastasis is very rare and accounts for only 0.8% of tonsillar tumors. And phyllodes tumor of the breast with tonsillar metastasis is very rare. CASE PRESENTATION: A 57-year-old Japanese woman received surgery (partial mastectomy) of malignant phyllodes tumor. Seven months after initial surgery, pharyngeal pain, swelling, and a feeling of dyspnea developed, and tumor was found in the left palatine tonsil. Computed tomography for further evaluation showed a tonsillar lesion with contrast enhancement, and tonsillar metastasis was suspected...
January 19, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28103572/low-rate-of-positive-margins-and-re-excision-after-partial-mastectomy-in-highly-selected-breast-cancer-patients-a-chinese-single-institution-experience
#10
Siyu Wu, Yanyan Zhu, Zhaozhi Yang, Miao Mo, Hongbo Gao, Wentao Yang, Guangyu Liu
A recent randomized controlled trial firstly demonstrated that cavity shaving significantly decreased the rate of positive margins and re-excision among partial mastectomy (PM) patients. However, it remains unknown whether cavity shaving should be routinely applied to Chinese breast cancer patients undergoing PM. A total of 408 PM patients undergoing 410 PMs among 1796 surgically treated breast cancer patients at Fudan University Shanghai Cancer Centre from January 2015 to June 2015 were included in our study...
January 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/28097778/does-smoking-history-confer-a-higher-risk-for-reconstructive-complications-in-nipple-sparing-mastectomy
#11
Jordan D Frey, Michael Alperovich, Jamie P Levine, Mihye Choi, Nolan S Karp
History of smoking has been implicated as a risk factor for reconstructive complications in nipple-sparing mastectomy (NSM), however there have been no direct analyses of outcomes in smokers and nonsmokers. All patients undergoing NSM at New York University Langone Medical Center from 2006 to 2014 were identified. Outcomes were compared for those with and without a smoking history and stratified by pack-year smoking history and years-to-quitting (YTQ). A total of 543 nipple-sparing mastectomies were performed from 2006 to 2014 with a total of 49 in patients with a history of smoking...
January 18, 2017: Breast Journal
https://www.readbyqxmd.com/read/28051266/one-stage-breast-reconstruction-techniques-in-elderly-patients-to-preserve-quality-of-life
#12
M Maruccia, M Mazzocchi, L A Dessy, M G Onesti
OBJECTIVE: The aim of this study was to review one-stage breast reconstruction techniques performed in elderly patients at our institution to identify the criteria of selection of each in terms of outcomes and quality of life. PATIENTS AND METHODS: Patients older than 65 years who underwent one-stage breast reconstruction between January 2004 and July 2014 at our hospital were included. Patients and procedure-related data were collected from the medical records...
December 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28046058/cavity-shaving-plus-lumpectomy-versus-lumpectomy-alone-for-patients-with-breast-cancer-undergoing-breast-conserving-surgery-a-systematic-review-and-meta-analysis
#13
Ke Wang, Yu Ren, Jianjun He
The margin status is a well-established prognostic predictor for patients undergoing breast-conserving surgery (BCS). Recent data suggested that cavity shaving in addition to lumpectomy might be a promising approach for improving the clinical outcomes. We aimed to compare the efficacy and safety between cavity shaving plus lumpectomy and lumpectomy alone with a systematic review and meta-analysis. We searched the PubMed, Embase, and Cochrane CENTRAL databases for studies comparing cavity shaving with lumpectomy before June 10, 2016...
2017: PloS One
https://www.readbyqxmd.com/read/28040452/delay-techniques-for-nipple-sparing-mastectomy-a-systematic-review
#14
REVIEW
Laurel S Karian, Paul J Therattil, Philip D Wey, Kevin T Nini
BACKGROUND: Rare but serious complications of nipple-sparing mastectomy (NSM) include necrosis of the nipple-areolar complex (NAC) and mastectomy skin flaps. NAC and mastectomy flap delay procedures are novel techniques designed to avoid these complications and may be combined with retroareolar biopsy as a first-stage procedure. We performed a systematic review of the literature to evaluate various techniques for NAC and mastectomy flap delay. METHODS: PubMed and Cochrane databases were searched from January 1975 through April 15, 2016...
February 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28028261/-two-cases-of-er-positive-postmenopausal-breast-cancer-that-increased-in-size-during-neoadjuvant-hormone-therapy
#15
Takanori Jinno, Yasuhiro Kurumiya, Tae Niwa, Ei Sekoguchi, Satoshi Kobayashi, Kiyotaka Kawai, Muneyasu Kiriyama
The first patient was a 62-year-old woman who was referred to our hospital with the complaint of a left breast tumor. She was diagnosed with invasive ductal carcinoma(T1N0M0, stage I). The tumor was ER-positive, PgR-negative, and HER2- negative. She was treated with toremifene, letrozole, and anastrozole as neoadjuvant hormone therapy for 4 months, but the tumor increased in size. The clinical response was judged as progressive disease, and a left partial mastectomy and axillary lymph node dissection were performed...
December 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28027233/microporous-polysaccharide-hemospheres-potentiate-ischemia-induced-skin-flap-necrosis-in-a-murine-model
#16
Anaeze C Offodile, Bin Chen, Andrew S Aherrera, Lifei Guo
BACKGROUND: Microporous polysaccharide hemospheres are an increasingly used adjunctive measure for obtaining operative field hemostasis. However, the impact of these agents on survival of vascularly challenged tissues is unknown. The aim of this study was to investigate the effect, if any, of microporous hemospheres on tissue survival in a murine model. METHODS: Eighteen Sprague-Dawley rats underwent creation of two flanking dorsal, modified McFarlane-style flaps using a length-to-width ratio of 4:1...
January 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27998656/impact-of-primary-tumor-surgery-in-stage-iv-male-breast-cancer
#17
Mahvish Muzaffar, Swapnil Kachare, Nasreen Vohra
BACKGROUND: Primary tumor surgery (PTS) is not a standard treatment modality in stage IV breast cancer. Retrospective studies in female breast cancer show improved survival in women undergoing PTS; however, data regarding the impact of surgery in male breast cancer are lacking. The objective of this study was to analyze the impact of PTS on survival among men with metastatic breast cancer. METHODS: A retrospective study was conducted of men diagnosed with metastatic breast cancer at diagnosis were identified from the Surveillance, Epidemiology, and End Results (SEER) database from 1988 to 2011...
November 22, 2016: Clinical Breast Cancer
https://www.readbyqxmd.com/read/27998306/intramammary-metastatic-melanoma-of-unknown-primary-origin-in-a-58-year-old-patient-a-case-report
#18
Zeina El-Tani, Christophe Duc, Thomas Gluecker, Olivier Cottier
BACKGROUND: Malignant melanoma metastasis to the breast is a rare disease. CASE PRESENTATION: We present the case of a 58-year-old postmenopausal Caucasian woman with metastatic malignant melanoma of unknown origin of the right breast. She presented with a palpable lump in the inferior quadrant of her right breast. The investigations concluded it was breast metastasis from a malignant melanoma of unknown origin. The treatment consisted of mastectomy and axillary lymph node dissection...
December 20, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27988987/survival-after-breast-conserving-surgery-with-whole-breast-or-partial-breast-irradiation-in-women-with-early-stage-breast-cancer-a-seer-data-base-analysis
#19
Surbhi Grover, Sommer Nurkic, Marie Diener-West, Shayna L Showalter
Randomized clinical trials have demonstrated equivalency in survival outcomes for early stage breast cancer patients treated with either mastectomy or breast-conserving surgery (BCS) with radiation. Recent, state-level data confirm comparable survival outcomes. Using Surveillance Epidemiology and End Research (SEER) data, we sought to evaluate survival outcomes among patients with early stage breast cancer treated with mastectomy, BCS with whole breast irradiation (BCS + WBI), or BCS with accelerated partial breast irradiation (BCS + APBI)...
December 18, 2016: Breast Journal
https://www.readbyqxmd.com/read/27986343/nation-scale-adoption-of-shorter-breast-radiation-therapy-schedules-can-increase-survival-in-resource-constrained-economies-results-from-a-markov-chain-analysis
#20
Atif J Khan, Raza Rafique, Waleed Zafar, Chirag Shah, Bruce G Haffty, Frank Vicini, Arif Jamshed, Yao Zhao
PURPOSE: Hypofractionated whole breast irradiation and accelerated partial breast irradiation (APBI) offer women options for shorter courses of breast radiation therapy. The impact of these shorter schedules on the breast cancer populations of emerging economies with limited radiation therapy resources is unknown. We hypothesized that adoption of these schedules would improve throughput in the system and, by allowing more women access to life-saving treatments, improve patient survival within the system...
February 1, 2017: International Journal of Radiation Oncology, Biology, Physics
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