Read by QxMD icon Read

low magnesium

Vincent Matthias Brandenburg, Nadine Kaesler, Rafael Kramann, Jürgen Floege, Nikolaus Marx
Disturbances in magnesium homeostasis are frequent clinical conditions, particularly the prevalence of hypomagnesaemia is high. However, it remains an open question which laboratory method is optimal to assess the magnesium level in the body. Most frequently physicians measure total magnesium in serum. Many associative data from observational studies point towards an association between low magnesium levels and increased cardiovascular risk as well as increased mortality. Vice versa, normal-to-high magnesium levels in patients with advanced renal failure translate to a better outcome...
October 2016: Deutsche Medizinische Wochenschrift
Jessica J Gruskos, Guangqian Zhang, Daniela Buccella
The study of intracellular metal ion compartmentalization and trafficking involved in cellular processes demands sensors with controllable localization for the measurement of organelle-specific levels of cations with sub-cellular resolution. We introduce herein a new two-step strategy for in situ anchoring and activation of a fluorescent Mg(2+) sensor within an organelle of choice, using a fast fluorogenic reaction between a tetrazine-functionalized pro-sensor, Mag-S-Tz, and a strained bicyclononyne conjugated to a genetically encoded HaloTag fusion protein of known cellular localization...
October 17, 2016: Journal of the American Chemical Society
Mauricio H Pontes, Jinki Yeom, Eduardo A Groisman
The synthesis of ribosomes is regulated by both amino acid abundance and the availability of ATP, which regenerates guanosine triphosphate (GTP), powers ribosomes, and promotes transcription of rRNA genes. We now report that bacteria supersede both of these controls when experiencing low cytosolic magnesium (Mg(2+)), a divalent cation essential for ribosome stabilization and for neutralization of ATP's negative charge. We uncover a regulatory circuit that responds to low cytosolic Mg(2+) by promoting expression of proteins that import Mg(2+) and lower ATP amounts...
October 8, 2016: Molecular Cell
Adriana N Mudryj, Harold M Aukema, Paul Fieldhouse, B Nancy Yu
Poor eating habits among children are associated with negative health outcomes. The objective of this study was to use pulse/soy consumption as an indicator to evaluate the eating profile of young Manitobans. Data from the Canadian Community Health Survey Cycle 2.2 were used for analysis and restricted to Manitoba residents aged 2 to 18 years (n = 1840). Consumers were identified as individuals who reported eating at least 1 pulse/soy product during their recall. On any given day, 8.2% of Manitobans reported consumption of pulses/soy...
July 19, 2016: Canadian Journal of Dietetic Practice and Research
Antonius Ljj Bronckers, Donacian M Lyaruu
Supraoptimal intake of fluoride (F) induces structural defects in forming enamel, dentin and bone and increases the risk of bone fractures. Enamel formation is most sensitive to low levels of F and the degree of enamel fluorosis depends on the mouse strain. What molecular mechanism is responsible for these differences in sensitivity is unclear. Maturation ameloblasts transport bicarbonates into enamel in exchange for Cl- to buffer protons released by forming apatites. We proposed that F-enhanced mineral deposition releases excess of protons that will affect mineralization in forming enamel...
October 12, 2016: Bone
Sajjad Jafari, R K Singh Raman, Chris H J Davies, Joelle Hofstetter, Peter J Uggowitzer, Jörg F Löffler
Magnesium (Mg) alloys have attracted great attention as potential materials for biodegradable implants. It is essential that an implant material possesses adequate resistance to cracking/fracture under the simultaneous actions of corrosion and mechanical stresses, i.e., stress corrosion cracking (SCC) and/or corrosion fatigue (CF). This study investigates the deformation behaviour of a newly developed high-strength low-alloy Mg alloy, MgZn1Ca0.3 (ZX10), processed at two different extrusion temperatures of 325 and 400°C (named E325 and E400, respectively), under slow strain tensile and cyclic tension-compression loadings in air and modified simulated body fluid (m-SBF)...
September 28, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Bani K Pathak, Surojit Mondal, Chandana Barat
The ability of the ribosome to assist in folding of proteins both in vitro and in vivo is well documented and is a non-translational function of the ribosome. The interaction of the unfolded protein with the peptidyltransferase centre (PTC) of the bacterial large ribosomal subunit is followed by release of the protein in the folding competent state and rapid dissociation of ribosomal subunits. Our studies demonstrate that the PTC specific antibiotics, chloramphenicol and blasticidin S inhibit unfolded protein mediated subunit dissociation...
October 14, 2016: Letters in Applied Microbiology
Biranchi Narayan Mohapatra, Sujit Kumar Lenka, Manoranjan Acharya, Chakradhar Majhi, Gouri Oram, Khetra Mohan Tudu
OBJECTIVE: To study the clinical profile of hypokalemic flaccid paralysis (HKFP) and to evaluate its causes. METHODS: Fifty cases of hypokalemic flaccid paralysis (HKFP) admitted between November 2012 to October 2014 were taken up in the study. Serum potassium level < 3.5 mmol/ltr has been taken as hypokalemia. All cases were studied for spot and/or 24 hour urinary sodium / potassium, serum potassium / calcium / magnesium. Hypokalemic periodic paralysis (HPP) were diagnosed if there was spot/24 hour urine potassium excretion < 20mmol/ltr in presence of hypokalemia and flaccid weakness without other causes...
May 2016: Journal of the Association of Physicians of India
N A Kamenos, G Perna, M C Gambi, F Micheli, K J Kroeker
To understand the effects of ocean acidification (OA) on marine calcifiers, the trade-offs among different sublethal responses within individual species and the emergent effects of these trade-offs must be determined in an ecosystem setting. Crustose coralline algae (CCA) provide a model to test the ecological consequences of such sublethal effects as they are important in ecosystem functioning, service provision, carbon cycling and use dissolved inorganic carbon to calcify and photosynthesize. Settlement tiles were placed in ambient pH, low pH and extremely low pH conditions for 14 months at a natural CO2 vent...
October 12, 2016: Proceedings. Biological Sciences
N Guess
BACKGROUND: Diets reduced or low in carbohydrates are becoming increasingly popular. The replacement foods and their accompanying nutrients determine the health effects of such diets. However, little is known about the dietary intake of people consuming reduced or low carbohydrate diets. METHODS: In this cross-sectional study, the dietary and nutrient intake of individuals aged 16-75 years consuming less than 40% of energy from carbohydrate (n = 430) was compared with individuals consuming equal to or more than 40% energy from carbohydrate (n = 1833) using the UK National Diet and Nutrition Survey...
October 12, 2016: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
Anja Simmet, Julia Depa, Peter Tinnemann, Nanette Stroebele-Benschop
Users of food pantries often have a long history of food insecurity and may be vulnerable to nutritional deficiencies. The quality of their diets is not well researched. The purpose of this systematic review was to summarize the published evidence about the dietary quality of food pantry users. Systematic database searches of PubMed, PsycINFO, PsycARTICLES, and Psychology Behavioral Sciences Collection, and hand searches of references were conducted to identify cross-sectional, cohort, and intervention studies reporting baseline data, conducted in high-income countries and published between 1980 and 2015, which reported on the nutritional adequacy of individuals who have used a food pantry at least once in the previous 12 months...
October 7, 2016: Journal of the Academy of Nutrition and Dietetics
Denis A Kuznetsov, Tamara A Bazhenova, Ivan V Fedyanin, Vyacheslav M Martynenko, Alexander F Shestakov, Galina N Petrova, Natal'ya S Komarova
A series of novel cluster compounds comprising molybdenum in a low valence state was synthesized by means of a disproportionation of the dimeric compound [Mo(+4)2Cl4(OCH3)4(CH3OH)2] (1). The reaction of 1 with CH3OH leads to the disproportionation of Mo(+4) yielding an unusual mixed-valence cluster [Mo(+3.5)4Cl4O2(OCH3)6(CH3OH)4] (2). By exploring this synthetic approach further, tri-{[Mo3Cl3(OCH3)7(CH3OH)3] (3)}, tetra-{[Mo4Cl4(OCH3)10(CH3OH)2] (4), [Mo4Cl3O(OCH3)9(CH3OH)3] (5), [Mo4Cl2(OCH3)12(CH3OH)2] (6)}, and hexanuclear {[Mo6Cl4O6(OCH3)10(CH3OH)2] (7)} molybdenum alkoxides were synthesized by the reaction of 1 with methanol and stoichiometric amounts of magnesium methoxide, thus providing a general facile access to the polynuclear methoxide complexes of a low-valence molybdenum...
October 18, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
Cristina Rostkowska, Caroline M Mota, Taísa C Oliveira, Fernanda M Santiago, Lilian A Oliveira, Gaspar H Korndörfer, Regina M Q Lana, Monica L Rossi, Neusa L Nogueira, Xavier Simonnet, Tiago W P Mineo, Deise A O Silva, José R Mineo
Artemisia annua is used as a source of artemisinin, a potent therapeutic agent used for the treatment of infectious diseases, chiefly malaria. However, the low concentration (from 0.01 to 1.4% of dried leaf matter) of artemisinin in the plant obtained with the traditional cropping system makes it a relatively expensive drug, especially in developing countries. Considering that artemisinin and silicon (Si) are both stored in A. annua glandular trichomes, and that Si accumulation has never been investigated, this study aimed to look into Si effects on A...
2016: Frontiers in Plant Science
Wen-Chiang Hong, Chieh-Jen Ku, Rui Li, Siamak Abbaslou, Pavel Reyes, Szu-Ying Wang, Guangyuan Li, Ming Lu, Kuang Sheng, Yicheng Lu
Building integrated photovoltaics (BIPV) have attracted considerable interests because of its aesthetically attractive appearance and overall low cost. In BIPV, system integration on a glass substrate like windows is essential to cover a large area of a building with low cost. However, the conventional high voltage devices in inverters have to be built on the specially selected single crystal substrates, limiting its application for large area electronic systems, such as the BIPV. We demonstrate a Magnesium Zinc Oxide (MZO) based high voltage thin film transistor (HVTFT) built on a transparent glass substrate...
October 10, 2016: Scientific Reports
Sana Sheikh, Rahat Najam Qureshi, Asif Raza Khowaja, Rehana Salam, Marianne Vidler, Diane Sawchuck, Peter von Dadelszen, Shujat Zaidi, Zulfiqar Bhutta
BACKGROUND: Maternal mortality ratio is 276 per 100,000 live births in Pakistan. Eclampsia is responsible for one in every ten maternal deaths despite the fact that management of this disease is inexpensive and has been available for decades. Many studies have shown that health care providers in low and middle-income countries have limited training to manage patients with eclampsia. Hence, we aimed to explore the knowledge of different cadres of health care providers regarding aetiology, diagnosis and treatment of pre-eclampsia and eclampsia and current management practices...
September 30, 2016: Reproductive Health
Mary Y Hu, Xuchu Deng, Kanchana Sahan Thanthiriwatte, Virgil E Jackson, Chuan Wan, Odeta Qafoku, David A Dixon, Andrew R Felmy, Kevin M Rosso, Jianzhi Hu
We report an in situ high pressure NMR capability that permits natural abundance (17)O and (25)Mg NMR characterization of dissolved species in aqueous solution and in the presence of supercritical CO2 fluid (scCO2). The dissolution of Mg(OH)2 (brucite) in a multiphase water/scCO2 fluid at 90 atm pressure and 50 °C was studied in situ, with relevance to geological carbon sequestration. (17)O NMR spectra allowed identification and distinction of various fluid species including dissolved CO2 in the H2O-rich phase, scCO2, aqueous H2O, and HCO3(-)...
October 10, 2016: Environmental Science & Technology
Maulee Hiromi Arambewela, Noel P Somasundaram, Chaminda Garusinghe
BACKGROUND: Hypernatremia is a frequent occurrence among hospitalized patients. Severe hypernatremia is associated with mortality rates of over 60 %. Extreme hypernatremia, defined as sodium levels >190 mmol/l, is a rare occurrence. The literature on electrocardiographic changes occurring with this degree of hypernatremia is extremely scarce. We report the case of an 11-year-old Sri Lankan girl who presented with sodium levels of 226 mmol/l following infusion with 3 % hypertonic saline who developed diffuse QT prolongation leading to fatal ventricular tachycardia...
October 1, 2016: Journal of Medical Case Reports
Yue Cao, Hao Ai, Ajay Jain, Xueneng Wu, Liang Zhang, Wenxia Pei, Aiqun Chen, Guohua Xu, Shubin Sun
BACKGROUND: Phosphorus (P), an essential macronutrient, is often limiting in soils and affects plant growth and development. In Arabidopsis thaliana, Low Phosphate Root1 (LPR1) and its close paralog LPR2 encode multicopper oxidases (MCOs). They regulate meristem responses of root system to phosphate (Pi) deficiency. However, the roles of LPR gene family in rice (Oryza sativa) in maintaining Pi homeostasis have not been elucidated as yet. RESULTS: Here, the identification and expression analysis for the homologs of LPR1/2 in rice were carried out...
October 3, 2016: BMC Plant Biology
Xiaodong Xing, Jingjing Wang, Xiaoyu Kuang, Xinxin Xia, Cheng Lu, George Maroulis
The effect of Mg doping on the growth behavior and the electronic properties of aluminum clusters has been investigated theoretically using the CALYPSO (Crystal structure AnaLYsis by Particle Swarm Optimization) method in combination with density functional theory calculations. Compared to pure aluminum clusters, the structure of Mg-doped clusters shows the charming transformation with increasing atomic number. The photoelectron spectra (PES) of the global minima of anionic Aln and AlnMg (n = 3-20) clusters have been calculated based on the time-dependent density functional theory (TD-DFT) method...
September 21, 2016: Physical Chemistry Chemical Physics: PCCP
Aino-Maija Eloranta, Taisa Venäläinen, Sonja Soininen, Henna Jalkanen, Sanna Kiiskinen, Ursula Schwab, Timo A Lakka, Virpi Lindi
BACKGROUND: Data on food sources of nutrients are needed to improve strategies to enhance nutrient intake among girls and boys in Western countries. OBJECTIVE: To identify major food sources of energy, energy nutrients, dietary fibre, and micronutrients, and to study gender differences in these food sources among children. DESIGN: We assessed food consumption and nutrient intake using 4-day food records in a population sample of Finnish girls (n=213) and boys (n=217) aged 6-8 years from the Physical Activity and Nutrition in Children Study...
2016: Food & Nutrition Research
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"