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Hawthorn effect

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https://www.readbyqxmd.com/read/29778435/hand-hygiene-compliance-rates-fact-or-fiction
#1
Mary-Louise McLaws, Yen Lee Angela Kwok
BACKGROUND: The mandatory national hand hygiene program requires Australian public hospitals to use direct human auditing to establish compliance rates. To establish the magnitude of the Hawthorne effect, we compared direct human audit rates with concurrent automated surveillance rates. METHODS: A large tertiary Australian teaching hospital previously trialed automated surveillance while simultaneously performing mandatory human audits for 20 minutes daily on a medical and a surgical ward...
May 16, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29735550/microrna-339-promotes-development-of-stem-cell-leukemia-lymphoma-syndrome-via-downregulation-of-the-bcl2l11-and-bax-pro-apoptotic-genes
#2
Tianxiang Hu, Yating Chong, Sumin Lu, Rebecca Wang, Haiyan Qin, Jeane Silva, Eiko Kitamura, Chang-Sheng Chang, LesleyAnn Hawthorn, John K Cowell
Development of myeloid and lymphoid neoplasms related to overexpression of FGFR1 kinases as a result of chromosome translocations depends on promotion of a stem cell phenotype, suppression of terminal differentiation, and resistance to apoptosis. These phenotypes are related to the stem cell leukemia/lymphoma syndrome (SCLL), which arises through the effects of activated FGFR1 kinase on gene transcription, including dysregulation of microRNAs. In a screen for miRNAs that are directly regulated by FGFR1 and that stimulate cell proliferation and survival, we identified miR-339-5p, which is highly upregulated in cells carrying various different chimeric kinases...
May 7, 2018: Cancer Research
https://www.readbyqxmd.com/read/29720209/cluster-randomised-controlled-trial-of-a-theory-based-multiple-behaviour-change-intervention-aimed-at-healthcare-professionals-to-improve-their-management-of-type-2-diabetes-in-primary-care
#3
Justin Presseau, Joan Mackintosh, Gillian Hawthorne, Jill J Francis, Marie Johnston, Jeremy M Grimshaw, Nick Steen, Tom Coulthard, Heather Brown, Eileen Kaner, Marko Elovainio, Falko F Sniehotta
BACKGROUND: National diabetes audits in the UK show room for improvement in the quality of care delivered to people with type 2 diabetes in primary care. Systematic reviews of quality improvement interventions show that such approaches can be effective but there is wide variability between trials and little understanding concerning what explains this variability. A national cohort study of primary care across 99 UK practices identified modifiable predictors of healthcare professionals' prescribing, advising and foot examination...
May 2, 2018: Implementation Science: IS
https://www.readbyqxmd.com/read/29672935/electrocardiographic-effects-of-hawthorn-crataegus-oxyacantha-in-healthy-volunteers-a-randomized-controlled-trial
#4
Stephanie E Trexler, Elaine Nguyen, Samantha M Gromek, Marcy J Balunas, William L Baker
The objective of this study was to evaluate the electrocardiographic effects of hawthorn in healthy adult volunteers. It was double-blind cross-over trial randomized 20 healthy adult volunteers to receive either a single oral 160-mg dose of hawthorn or matching placebo. Triplicate 12-lead electrocardiograms were taken before treatment and at 1-, 2-, 4-, and 6-hr post-dose. Following at least a 7-day washout period, participants were crossed over to the opposing treatment arm and had the measurements repeated...
April 19, 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29660753/crataegus-special-extract-ws-1442-effects-on-enos-and-microrna-155
#5
Xinwen Wang, Yan Liang, Jian Shi, Hao-Jie Zhu, Barry E Bleske
Increased expression of microRNA 155 (miR-155) results in a decrease in endothelial nitric oxide synthase (eNOS) expression and impaired endothelial function. Factors that have been shown to increase expression of miR-155 may be mitigated by WS 1442, an extract of hawthorn leaves and flowers ( Crataegus special extract) that contains a range of pharmacologically active substances including oligomeric proanthocyanidins and flavonoids. The purpose of this study is to determine the effect of WS 1442 on the expression of miR-155 and eNOS in the presence of tumor necrosis factor (TNF- α )...
April 16, 2018: Planta Medica
https://www.readbyqxmd.com/read/29655677/an-in-vitro-and-in-vivo-study-of-a-4-herb-formula-on-the-management-of-diet-induced-metabolic-syndrome
#6
Elaine Wat, Yanping Wang, Ken Chan, Hon Wai Law, Chi Man Koon, Kit Man Lau, Ping Chung Leung, Choly Yan, Clara Bik San Lau
BACKGROUND: Metabolic syndrome is the cluster of risk factors that leads to increased episodes of cardiovascular disease (CVD). These risk factors include but are not limited to obesity, non-alcoholic fatty liver (NAFLD), dyslipidemia, and type 2 diabetes. Since the pathogenesis of metabolic syndrome has multiple metabolic origins, there is no single treatment for it. Pharmacological approaches consist of separate drugs which target at individual risk factors which pose various side effects...
March 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29655581/paternal-understanding-of-menstrual-concerns-in-young-women
#7
Jane E Girling, Samuel Cj Hawthorne, Jennifer L Marino, Abdul G Nur Azurah, Sonia R Grover, Yasmin L Jayasinghe
STUDY OBJECTIVE: No studies have specifically considered paternal understanding of menstruation. This study aimed to establish the degree of understanding of fathers of adolescent girls with menstrual symptoms relative to mothers. DESIGN AND SETTING: This is a cross-sectional survey-based study. Adolescent patients attending an outpatient gynaecology clinic for dysmenorrhoea and/or heavy menstrual bleeding (HMB) and their parents were invited to complete surveys...
April 12, 2018: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/29644566/effects-of-enzyme-supplementation-on-the-nutrient-amino-acid-and-energy-utilization-efficiency-of-citrus-pulp-and-hawthorn-pulp-in-linwu-ducks
#8
Xu Zhang, Haobang Li, Guitao Jiang, Xiangrong Wang, Xuan Huang, Chuang Li, Duanqin Wu, Qiuzhong Dai
The objective of this study was to evaluate the effects of enzyme supplementation on the nutrient, amino acid, and energy utilization efficiency of citrus pulp and hawthorn pulp as unusual feedstuffs in Linwu ducks. Forty ducks were assigned to each treatment group and fed diets with or without complex enzyme supplementation. All birds received the same quantity of raw material (60 g) via the force-feeding procedure. With the exception of leucine and phenylalanine, amino acid concentrations in hawthorn pulp were twice those in citrus pulp...
April 11, 2018: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29604674/the-effect-of-sentential-context-on-phonetic-categorization-is-modulated-by-talker-accent-and-exposure
#9
Jessamyn Schertz, Kara Hawthorne
Higher-level factors, including the contextual plausibility of competing word candidates, interact with lower-level phonetic cues to influence how listeners interpret the speech signal. This work shows that listeners' phonetic categorization (e.g., coat versus goat) is more heavily influenced by sentential context when listening to a non-native versus native talker. Further, the effect of context on phonetic categorization decreases as the listener becomes familiar with the talker's phonetic characteristics, for both native and non-native talkers...
March 2018: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/29584464/endophyte-enhanced-phytoremediation-of-dde-contaminated-using-cucurbita-pepo-a-field-trial
#10
N Eevers, J R Hawthorne, J C White, J Vangronsveld, N Weyens
Although the use of the pesticide 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane (DDT) was banned from the mid-1970s, its most abundant and recalcitrant degradation product, 2,2-bis(p-chlorophenyl)-1,1-dichloro-ethylene (DDE), is still present in terrestrial and aquatic ecosystems worldwide. Zucchini (Cucurbita pepo ssp. pepo) has been shown to accumulate high concentrations of DDE and was proposed for phytoremediation of contaminated soils. We performed a field trial covering a full plant life cycle. C. pepo plants inoculated with the plant growth-promoting endophytic strains Sphingomonas taxi UH1, Methylobacterium radiotolerans UH1, Enterobacter aerogenes UH1, or a consortium combining these 3 strains were grown on a DDE-contaminated field for 100 days...
March 21, 2018: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/29580743/surgical-trends-in-arthroscopic-hip-surgery-using-a-large-national-database
#11
Nicholas A Bonazza, Brittany Homcha, Guodong Liu, Douglas L Leslie, Aman Dhawan
PURPOSE: To assess the practice trends in hip arthroscopy, including femoroplasty, acetabuloplasty, and labral repair Current Procedure Terminology, 4th edition (CPT-4), codes that have been implemented since many of the previous studies were published, without concerns for Hawthorne or observer effect as can be seen during a board collection window, and in a larger volume of patients with a more comprehensive database than previous published data. METHODS: The MarketScan Commercial Claims and Encounters database was searched using CPT-4 codes to identify patients who underwent any arthroscopic hip procedure from 2008 to 2013...
March 23, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29496171/resveratrol-combined-with-total-flavones-of-hawthorn-alleviate-the-endothelial-cells-injury-after-coronary-bypass-graft-surgery
#12
Ying Zhu, Bing Feng, Songmin He, Zuqing Su, Guangjuan Zheng
OBJECTIVE: To explore the preventive and therapeutic effects of Resveratrol combined with total flavones of hawthorn, compatibility of traditional Chinese medicines, on the endothelial cells injury after artery bypass graft surgery. METHODS: The animal model of coronary artery bypass grafting (CABG) was prepared by transplanting a segment of autologous jugular vein onto the transected common carotid artery in rabbits. After CABG surgery, the rabbits were administrated with saline (model group), aspirin (Aspirin group), resveratrol (Res group), total flavones of hawthorn (Haw group) and resveratrol combined with total flavones of hawthorn (Res+Haw group) once a day for eight weeks, respectively...
February 1, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29477546/-efficacy-of-the-strategy-to-improve-the-quality-indicators-of-diabetes-mellitus-2-care-process-in-advanced-diabetes-centre-macarena
#13
Juan Manuel Vélez, Rosa García, Enrique Pina, Cristóbal Morales, Carmen Escalera, Antonio Ortega, Blas Poyatos, Dolores Carrasco, Jesús Prieto, M Ángeles Eslava, J Antonio Corrales, María O Barón, Mercedes Llano, Francisco Ruiz, Romualdo Sánchez, Manuel Victorino Pino, M Luisa Redondo, Antonio Castellanos, Eduardo Mayoral
INTRODUCTION: The assessment of the Diabetes Mellitus 2 Care Process (PAI-DM2) through the assessment tool for the chronic illness' care models (IEMAC-Diabetes) allows the design of health interventions for the improvement of medical care. OBJECTIVE: Analysing the quality of healthcare provided to DM2 patients. DESIGN: Quasiexperimental study before and after intervention with a not randomised control group. LOCATION: Health care district of primary care Sevilla...
February 21, 2018: Atencion Primaria
https://www.readbyqxmd.com/read/29368658/health-laparoscopic-supracervical-hysterectomy-versus-second-generation-endometrial-ablation-for-the-treatment-of-heavy-menstrual-bleeding-study-protocol-for-a-randomised-controlled-trial
#14
Kevin Cooper, Kirsty McCormack, Suzanne Breeman, Jessica Wood, Neil W Scott, Justin Clark, Jed Hawe, Robert Hawthorn, Kevin Phillips, Angela Hyde, Alison McDonald, Mark Forrest, Samantha Wileman, Graham Scotland, John Norrie, Siladitya Bhattacharya
BACKGROUND: Heavy menstrual bleeding (HMB) is a common problem affecting approximately 1.5 million women in England and Wales with a major impact on their physical, emotional, social and material quality of life. It is the fourth most common reason why women attend gynaecology outpatient clinics and accounts for one-fifth of all gynaecology outpatient referrals. Initial treatment in primary care is medical - either by means of oral or injected medication or the levonorgestrel-intrauterine system (Mirena®)...
January 24, 2018: Trials
https://www.readbyqxmd.com/read/29361363/hand-hygiene-hall-monitors-leveraging-the-hawthorne-effect
#15
Emily G McDonald, Elizabeth Smyth, Lulu Smyth, Todd C Lee
Unfortunately, more than a decade after the World Health Organization's campaign launched, many centers still face challenges with low rates of hand hygiene compliance. Several electronic hand hygiene monitoring systems are available, and the cost of setup and maintenance varies by institution. At our institution, with extremely limited funds for complex interventions, we instead hired a pragmatic teenager in search of a summer job and trained her as a hand hygiene "hall monitor." We describe an effective, inexpensive intervention that improved our unit's hand hygiene performance while also providing youth employment...
January 17, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29348647/the-contribution-of-predators-and-scavengers-to-human-well-being
#16
REVIEW
Christopher J O'Bryan, Alexander R Braczkowski, Hawthorne L Beyer, Neil H Carter, James E M Watson, Eve McDonald-Madden
Predators and scavengers are frequently persecuted for their negative effects on property, livestock and human life. Research has shown that these species play important regulatory roles in intact ecosystems including regulating herbivore and mesopredator populations that in turn affect floral, soil and hydrological systems. Yet predators and scavengers receive surprisingly little recognition for their benefits to humans in the landscapes they share. We review these benefits, highlighting the most recent studies that have documented their positive effects across a range of environments...
February 2018: Nature Ecology & Evolution
https://www.readbyqxmd.com/read/29326192/evidence-for-sample-selection-effect-and-hawthorne-effect-in-behavioural-hiv-prevention-trial-among-young-women-in-a-rural-south-african-community
#17
Molly Rosenberg, Audrey Pettifor, Rhian Twine, James P Hughes, F Xavier Gomez-Olive, Ryan G Wagner, Afolabi Sulaimon, Stephen Tollman, Amanda Selin, Catherine MacPhail, Kathleen Kahn
OBJECTIVES: We examined the potential influence of both sample selection effects and Hawthorne effects in the behavioural HIV Prevention Trial Network 068 study, designed to examine whether cash transfers conditional on school attendance reduce HIV acquisition in young South African women. We explored whether school enrolment among study participants differed from the underlying population, and whether differences existed at baseline (sample selection effect) or arose during study participation (Hawthorne effect)...
January 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29288081/effect-of-poly-ethylene-glycol-on-insulin-stability-and-cutaneous-cell-proliferation-in-vitro-following-cytoplasmic-delivery-of-insulin-loaded-nanoparticulate-carriers-a-potential-topical-wound-management-approach
#18
Dalia H Abdelkader, Mohamed A Osman, Sanaa A El-Gizawy, Susan J Hawthorne, Ahmed M Faheem, Paul A McCarron
We describe the development of a nanoparticulate system, with variation of poly(ethylene glycol) (PEG) content, capable of releasing therapeutic levels of bioactive insulin for extended periods of time. Recombinant human insulin was encapsulated in poly(d,l-lactide-co-glycolide) nanoparticles, manufactured with variation in poly(ethylene glycol) content, and shown to be stable for 6days using SDS-PAGE, western blot and MALDI MS. To determine if insulin released from this sustained release matrix could stimulate migration of cell types normally active in dermal repair, a model wound was simulated by scratching confluent cultures of human keratinocytes (HaCaT) and fibroblasts (Hs27)...
March 1, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29277104/the-importance-of-the-hawthorne-effect-on-psychological-outcomes-unveiled-in-a-randomized-controlled-trial-of-diabetes-technology
#19
Mary B Abraham, Jennifer A Nicholas, Michael Crone, Trang T Ly, Elizabeth A Davis, Timothy W Jones
No abstract text is available yet for this article.
December 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29244241/vitamin-d-and-gestational-diabetes-mellitus-a-systematic-review-based-on-data-free-of-hawthorne-effect
#20
REVIEW
Y Zhang, Y Gong, H Xue, J Xiong, G Cheng
BACKGROUND: Gestational diabetes mellitus (GDM) is an increasingly prevalent disorder, associated with low blood vitamin D level. OBJECTIVES: To evaluate the relationship between vitamin D and GDM. SEARCH STRATEGY: EMBASE, MEDLINE, Cochrane Library and China Biology Medicine disc were searched up to May 2017. The references of previous studies were screened. SELECTION CRITERIA: Observational studies on the relationship between vitamin D and GDM free from Hawthorne effect and randomised controlled trials of vitamin D supplementation during pregnancy for preventing or treating GDM were included...
December 15, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
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