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videocapsule endoscopy

Edward J Ciaccio, Govind Bhagat, Suzanne K Lewis, Peter H Green
BACKGROUND: Videocapsule endoscopy is a relative new method to analyze the gastrointestinal tract for the presence of pathologic features. It is of relevance to detect villous atrophy in the small bowel, which is a defining symptom of celiac disease. METHOD: In this tutorial, methods to extract and process videocapsule endoscopy data are elucidated. The algorithms, computer code, and paradigms to analyze image series are described in detail. The topics covered include extraction of data, analysis of texture, eigenanalysis, spectral analysis, three-dimensional projection, and estimation of motility...
September 16, 2016: Computers in Biology and Medicine
Uri Kopylov, Diana E Yung, Tal Engel, Tomer Avni, Robert Battat, Shomron Ben-Horin, John N Plevris, Rami Eliakim, Anastasios Koulaouzidis
BACKGROUND AND AIMS: Fecal calprotectin is a well-established marker of mucosal inflammation. Although the correlation of elevated calprotectin levels with colonic inflammation has been confirmed repeatedly, it is less established for the small bowel. The aim of the current study was to assess the diagnostic accuracy of calprotectin for the prediction of active small-bowel disease on capsule endoscopy by performing a diagnostic test meta-analysis. MATERIALS AND METHODS: A comprehensive search was performed using PubMed/Embase...
October 2016: European Journal of Gastroenterology & Hepatology
Mihai Rimbaş, Denise Carmen Mihaela Zahiu, Andrei Mihai Voiosu, Theodor Alexandru Voiosu, Alina Ana-Maria Zlate, Roxana Dinu, Domenico Galasso, Leonardo Minelli Grazioli, Mariachiara Campanale, Federico Barbaro, Bogdan Radu Mateescu, Bogdan Busuioc, Tiberiu Iordache, Oana Dolofan, Adelina Maria Popescu, Vasile Daniel Balaban, Mircea Mihai Raducan, Cristiano Spada, Cristian Răsvan Băicuş, Guido Costamagna
BACKGROUND AND STUDY AIMS: In videocapsule endoscopy examination (VCE), subtle variations in mucosal hue or pattern such as those seen in ulcerations can be difficult to detect, depending on the experience of the reader. Our aim was to test whether virtual chromoendoscopy (VC) techniques, designed to enhance the contrast between the lesion and the normal mucosa, could improve the characterization of ulcerative mucosal lesions. PATIENTS AND METHODS: Fifteen trainees or young gastroenterologists with no experience in VCE were randomly assigned to evaluate 250 true ulcerative and 100 false ulcerative, difficult-to-interpret small bowel lesions, initially as white light images (WLI) and then, in a second round, with the addition of one VC setting or again as WLI, labeling them as real lesions or artifacts...
May 2016: Endoscopy International Open
Aldo Bonaventura, Luca Liberale, Nadia Hussein El-Dib, Fabrizio Montecucco, Franco Dallegri
BACKGROUND: Blue rubber bleb nevus syndrome (BRBNS) is a rare disease characterized by vascular malformations mostly involving skin and gastrointestinal tract. This disease is often associated with sideropenic anemia and occult bleeding. METHODS: We report the case of chronic severe anemia in an old patient under oral anticoagulation treatment for chronic atrial fibrillation. RESULTS: At admission, the patient also presented fever and increased laboratory parameters of systemic inflammation (ferritin 308 mcg/L, C-reactive protein (CRP) 244 mg/L)...
2016: Clinical Laboratory
João Santos-Antunes, Hélder Cardoso, Susana Lopes, Margarida Marques, Amadeu C R Nunes, Guilherme Macedo
AIM: To analyze therapeutic changes in Crohn's disease (CD) patients following video capsule endoscopy (VCE) and to assess the usefulness of Lewis score and the Patency Capsule. METHODS: Patency Capsule was performed in every patient that had indication for VCE, and those with negative patency did not undergo VCE. Patients with established CD that underwent VCE between January 2011 and February 2014 were selected for this study; those with suspected CD were excluded, independent of VCE results, since our purpose was to address differences in therapeutic regimen in CD patients before and after VCE...
November 28, 2015: World Journal of Gastroenterology: WJG
Iolanda Ribeiro, Rolando Pinho, Adélia Rodrigues, Joana Silva, Ana Ponte, Jaime Rodrigues, João Carvalho
BACKGROUND AND AIMS: There are contradictory findings regarding long-term outcome in patients with obscure gastrointestinal bleeding and negative capsule endoscopy. Factors associated with rebleeding after a negative videocapsule are not entirely known. OBJECTIVE: The aim of this study was to compare the rebleeding rate between negative and positive capsule endoscopy patients and to identify predictive factors for rebleeding in patients with negative findings. MATERIAL AND METHODS: Consecutive patients with obscure gastrointestinal bleeding referred to a single center over a period of 5 years were identified...
November 2, 2015: Revista Española de Enfermedades Digestivas
Mihai Rimbaş, Mihail Radu Voiosu
Because the ileocecal valve could theoretically influence the progression of the videocapsule, we aimed to characterize its posed delay in videocapsule passage to the cecum. A retrospective study was conducted of all procedures in which patients experienced in the same day colonoscopy with ileal biopsy and videocapsule endoscopy. In all 11 patients who satisfied the criteria, at least one biopsy-induced ileal mucosal defect could be identified. There was a mean delay in the passage of the videocapsule through the ileocecal valve of more than 43 minutes (range: 9 seconds to 143 minutes)...
October 9, 2015: Gastroenterology Nursing: the Official Journal of the Society of Gastroenterology Nurses and Associates
Gabriel Carrilero-Zaragoza, Guillermo Carbonell-López del Castillo, Gema Ruiz-García, Juan Egea-Valenzuela, Paula Tomas-Pujante, Elena Iglesias Jorquera, Josefa Parra García, Antonio Sánchez Torres, Elena Navarro Noguera, Esther Estrella Díaz, Luis Fernando Carballo Álvarez
No abstract text is available yet for this article.
July 2015: Revista Española de Enfermedades Digestivas
Clara Benedetta Conti, Alessandra Baccarin, Dario Conte, Mirella Fraquelli
Present case report refers to a 48-year-old man with genetic haemochromatosis (C282Y mut/mut) diagnosed at the age of 26. After aggressive iron depleting regimen carried out up to normalization of iron-related indexes, he received a maintenance regimen based on regular phlebotomies for about 20 years. In 2014, a marked reduction of both serum ferritin and transferrin saturation percent, without concomitant anaemia, was noted on two different occasions at 5-month interval. An obscure occult GI bleeding was suspected, but both upper and lower GI tract endoscopy were negative for abnormal findings, as also was a detailed abdominal US scan...
October 2015: Internal and Emergency Medicine
Gianluca Ianiro, Stefano Bibbò, Silvia Pecere, Antonio Gasbarrini, Giovanni Cammarota
Currently, standard endoscopy is not considered enough reliable for the evaluation of celiac disease, neither to drive biopsy sampling. The diagnostic reliability of the endoscopic assessment of celiac disease has been increased by the recent advancement of software and hardware technologies. Several endoscopic technologies have been investigated so far for the diagnostic evaluation of celiac disease, including: water-immersion techniques, dye-based and dye-less chromoendoscopy techniques (Narrow band imaging; Fujinon Intelligeng Chromo Endoscopy; I-scan); optical coherence tomography; confocal laser endomicroscopy; high-resolution magnification endoscopy; videocapsule endoscopy; enteroscopy...
October 1, 2015: Computers in Biology and Medicine
Emanuele Rondonotti, Silvia Paggi
BACKGROUND: Because of its technical characteristics (i.e. 8-fold magnification, capability to inspect the entire small bowel) and minimal invasiveness, videocapsule endoscopy (VCE) has been proposed as a useful tool for managing patients with celiac disease (CD). KEY MESSAGES: Although VCE has been found to be highly sensitive and specific in identifying CD endoscopic markers, it is still inadequate to replace esophagogastroduodenoscopy (EGD) with biopsies in the diagnosis of CD...
2015: Digestive Diseases
Juan Egea-Valenzuela, Fernando Alberca-de-Las-Parras, Fernando Carballo-Álvarez
INTRODUCTION: The levels of calprotectin in the stools are proportional to neutrophil activity in the enteric lumen, so fecal calprotectin is a useful intestinal inflammatory biomarker. It is an extended tool as predictor of colonic pathology but there is scare evidence about its utility in the small bowel. OBJECTIVE: To test the yield of fecal calprotectin to detect lesions in the small bowel. MATERIAL AND METHODS: We have retrospectively included 71 patients sent for small bowel capsule endoscopy in study for suspected inflammatory bowel disease...
April 2015: Revista Española de Enfermedades Digestivas
Edward J Ciaccio, Govind Bhagat, Suzanne K Lewis, Peter H Green
We outline the use of quantitative techniques that are currently used for analysis of celiac disease. Image processing techniques can be useful to statistically analyze the pixular data of endoscopic images that is acquired with standard or videocapsule endoscopy. It is shown how current techniques have evolved to become more useful for gastroenterologists who seek to understand celiac disease and to screen for it in suspected patients. New directions for focus in the development of methodology for diagnosis and treatment of this disease are suggested...
March 7, 2015: World Journal of Gastroenterology: WJG
(no author information available yet)
No abstract text is available yet for this article.
February 2015: Journal of Crohn's & Colitis
(no author information available yet)
No abstract text is available yet for this article.
February 2015: Journal of Crohn's & Colitis
Uri Kopylov, Ernest G Seidman
PURPOSE OF REVIEW: This review summarizes the recent developments in the evaluation of small bowel disorders using videocapsule endoscopy (VCE) and serological and breath-test biomarkers. RECENT FINDINGS: The ability to visualize the small bowel was revolutionized with the introduction of VCE technology. VCE allows for accurate, noninvasive visualization of the small bowel mucosa. This device is invaluable in the investigation of obscure gastrointestinal bleeding (OGIB), occult bleeding with iron deficiency anaemia, small bowel Crohn's disease (CD), small bowel neoplasms and other mucosal disorders...
March 2015: Current Opinion in Gastroenterology
L Meziou, A Histace, F Precioso, O Romain, X Dray, B Granado, B J Matuszewski
Visualization of the entire length of the gastrointestinal tract through natural orifices is a challenge for endoscopists. Videoendoscopy is currently the "gold standard" technique for diagnosis of different pathologies of the intestinal tract. Wireless capsule endoscopy (WCE) has been developed in the 1990s as an alternative to videoendoscopy to allow direct examination of the gastrointestinal tract without any need for sedation. Nevertheless, the systematic postexamination by the specialist of the 50,000 (for the small bowel) to 150,000 images (for the colon) of a complete acquisition using WCE remains time-consuming and challenging due to the poor quality of WCE images...
2014: International Journal of Biomedical Imaging
Naoki Ohmiya, Yoshihito Nakagawa, Mituso Nagasaka, Tomomitsu Tahara, Tomoyuki Shibata, Masanao Nakamura, Yoshiki Hirooka, Hidemi Goto, Ichiro Hirata
Small-bowel bleeding comprises a majority of obscure gastrointestinal bleeding, but is caused by various kinds of diseases. For its diagnosis, history-taking and physical examination is requisite, leading to a suspicion of what diseases are involved. Next, cross-sectional imaging such as computed tomography should be done, followed by the latest enteroscopy, videocapsule endoscopy and deep enteroscopy according to the severity of hemorrhage and patient conditions. After comprehensive diagnosis, medical, enteroscopic, or surgical treatment should be selected...
March 2015: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
T Kishi, K Shimizu, S Hashimoto, H Onoda, Y Washida, I Sakaida, N Matsunaga
OBJECTIVE: To evaluate the CT enteroclysis (CTE)/enterography findings of patients with small-bowel mucosal damage induced by aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) and to compare these findings with the duration of drug use and endoscopic findings. METHODS: CTE findings of 11 patients (22 lesions) with drug-induced small-bowel damage were reviewed, including 8 NSAID users and 3 aspirin users. Three patients were short-term users (6 months or shorter) and eight were long-term users (3 years or longer)...
December 2014: British Journal of Radiology
Edward J Ciaccio, Christina A Tennyson, Govind Bhagat, Suzanne K Lewis, Peter H Green
Celiac disease commonly occurs in approximately 1% of populations, but it can be difficult to diagnose. The standard method to diagnose celiac disease includes analysis of endoscopy images of the small intestinal mucosa to detect presence of villous atrophy, which can be subtle. We have devised a means to improve the image-based detection of villous atrophy and other abnormality in videocapsule endoscopy by means of incorporating basis images. Basis images were extracted from a series of 200 consecutive image frames acquired over 100 seconds at the level of the duodenal bulb in 13 celiac patients and in 13 controls...
2014: Bio-medical Materials and Engineering
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