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https://www.readbyqxmd.com/read/28160241/retinal-haemorrhages-in-a-university-hospital-not-always-abusive-head-injury
#1
M Mattheij, C Venstermans, I de Veuster, I Vanderstraete, T Menovsky, P Jorens, B Ceulemans
Retinal haemorrhages (RH) and subdural haematomas (SDH) are frequently seen in abusive head trauma (AHT). The aim of our study is to show that they are suggestive, but not pathognomonic for AHT. We performed an observational retrospective study on children, aged 1-18 months old, admitted to the Antwerp University Hospital with RH. History, physical examination, medical course, coagulation and metabolic tests, skeletal survey, head circumference, retinal findings, cerebral imaging, and evaluation reports by social services or civil/criminal courts were collected...
February 3, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28137902/lhermitte-duclos-disease-associated-to-cowden-syndrome-de-novo-diagnosis-and-management-of-these-extremely-rare-syndromes-in-a-patient
#2
Ivo Gama, Leonor Almeida
A 36-year-old woman, with history of cutaneous papilomatosis and thyroid carcinoma presented with headache, transitory visual blurring and nausea. Funduscopy showed papilloedema. MRI showed a tumour of the right cerebellar hemisphere with a striated, tigroid pattern, typical of Lhermitte-Duclos disease (LDD). Significant clinical and perimetric improvements were noted after surgery and the follow-up did not reveal recurrences of the tumour. LDD is an extremely rare differential diagnosis of posterior fossa tumours...
January 30, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28130349/optic-disc-haemorrhages-at-baseline-as-a-risk-factor-for-poor-outcome-in-the-idiopathic-intracranial-hypertension-treatment-trial
#3
Michael Wall, Matthew J Thurtell
BACKGROUND: The risk of optic disc haemorrhages on visual outcome in idiopathic intracranial hypertension (IIH) is unknown. We report the type and frequency of optic disc haemorrhages and other funduscopic abnormalities at baseline in the study eye of the 133 subjects enrolled in the Idiopathic Intracranial Hypertension Treatment Trial completing 6 months of follow-up. METHODS: We reviewed optic disc photographs to tabulate the frequency and type of optic disc haemorrhages, other funduscopic abnormalities and papilloedema grades of the study eye at baseline and analyse if their presence is associated with a poor visual outcome...
January 27, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27981458/bariatric-surgery-or-non-surgical-weight-loss-for-idiopathic-intracranial-hypertension-a-systematic-review-and-comparison-of-meta-analyses
#4
REVIEW
James H Manfield, Kenny K-H Yu, Evangelos Efthimiou, Ara Darzi, Thanos Athanasiou, Hutan Ashrafian
BACKGROUND: Idiopathic intracranial hypertension (IIH) is associated with obesity and weight loss by any means is considered beneficial in this condition. OBJECTIVES: This study aims to appraise bariatric surgery vs. non-surgical weight-loss (medical, behavioural and lifestyle) interventions in IIH management. METHODS: A systematic review and meta-analyses of surgical and non-surgical studies. RESULTS: Bariatric surgery achieved 100% papilloedema resolution and a reduction in headache symptoms in 90...
February 2017: Obesity Surgery
https://www.readbyqxmd.com/read/27974106/fulminant-bilateral-papilloedema-during-low-dose-steroid-taper-in-a-child-with-systemic-idiopathic-arthritis-treated-with-tocilizumab
#5
Lulu Burstzyn, Simon Levin, Brian Rotenberg, Tamara Van Hooren, Andrew Leung, Roberta Berard, Daniela S Ardelean
Systemic juvenile idiopathic arthritis (SJIA) is one of the most severe forms of arthritis that affects children younger than 16 years of age at onset. SJIA often requires corticosteroids to control the inflammation. However, long-term corticosteroid use may have adverse effects, including intracranial hypertension (IH). Biologic therapies have been used as corticosteroid sparing agents. We report the first case of a child with steroid-dependent SJIA treated with tocilizumab, an IL-6 receptor monoclonal antibody, who developed fulminant IH, bilateral papilloedema and vision loss when oral prednisone was weaned from 2 to 1 mg per day...
December 14, 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27932429/igg4-related-disease-presenting-with-headache-and-papilloedema
#6
Eva Patrícia Lourenço, Hipólito Nzwalo, Mário Rui Sampaio, Luís Afonso
No abstract text is available yet for this article.
December 8, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27928421/asymmetrical-intraocular-pressures-and-asymmetrical-papilloedema-in-pseudotumor-cerebri-syndrome
#7
Mitchell Lawlor, Michael G Zhang, Jonathan Virgo, Gordon T Plant
This report is of two cases of asymmetrical papilloedema in patients with asymmetrical intraocular pressures (IOPs). The first patient presented with headaches, transient visual obscurations (TVOs), and elevated IOPs, and was found to have increased intracranial pressure caused by a torcula meningioma. He developed papilloedema after his IOPs were pharmacologically lowered; the papilloedema resolved after the IOP became elevated again after stopping his glaucoma drops, and then again returned as the IOP reduced when the drops were restarted...
December 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27928409/advanced-vestibular-schwannoma-a-case-of-optic-disc-oedema-without-hydrocephalus
#8
Rita Joana Castro Matos, Pedro Nuno Beirão Cardoso Quadrado Gil, Joana Margarida Silva Pires, Nádia Lopes
A wide range of pathologies can cause papilloedema. Vestibular schwannoma is a benign and slow-growing tumour that causes symptoms and findings on ophthalmic examination when the diagnostic is delayed. The authors report a case of a 64-year-old male who presented with bilateral disc oedema secondary to a vestibular schwannoma grade 4. Obstructive hydrocephalus was not evident. The authors suggest that cerebrospinal fluid protein may have a role in the formation of optic disc oedema. A right suboccipital craniectomy was performed to remove the tumour, leading to secondary facial palsy...
October 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27928403/increased-prevalence-of-optic-disc-drusen-after-papilloedema-from-idiopathic-intracranial-hypertension-on-the-possible-formation-of-optic-disc-drusen
#9
Faith A Birnbaum, Gabriella M Johnson, Lenworth N Johnson, Bokkwan Jun, Jason T Machan
This is a 25-year observational retrospective review of 372 consecutive participants with optic disc drusen or resolved papilloedema from idiopathic intracranial hypertension. The prevalence of optic disc drusen at 19% among eyes with resolved papilloedema was approximately 10 times higher and significantly increased (p < 0.001) as compared with the occurrence in the general population. Eyes with both resolved papilloedema and optic disc drusen had similar visual acuity and visual field outcome as compared with resolved papilloedema alone...
August 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27928402/neuroimaging-features-of-idiopathic-intracranial-hypertension-persist-after-resolution-of-papilloedema
#10
Randy O Chang, Brigid K Marshall, Noushin Yahyavi, Aseem Sharma, Julia Huecker, Mae O Gordon, Collin McClelland, Gregory P Van Stavern
Papilloedema is a key clinical finding in the diagnosis of idiopathic intracranial hypertension (IIH). However, newly proposed criteria allow diagnosis without papilloedema only if certain neuroimaging features are present. It is currently unclear if these findings persist upon resolution of papilloedema and IIH. A retrospective chart review identified three groups of patients (six per group) who had received orbital imaging within 4 weeks of fundoscopic examination: (1) IIH patients without active papilloedema, (2) IIH patients with active papilloedema, and (3) patients with no history of IIH or papilloedema...
August 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27928378/sixth-nerve-palsy-in-paediatric-intracranial-hypertension
#11
Julia E Reid, Rachel E Reem, Shawn C Aylward, David L Rogers
The purpose of this study was to report the incidence and describe the characteristics of sixth cranial nerve (CN VI) palsy in paediatric patients with intracranial hypertension (IH). A retrospective chart review of central Ohio children diagnosed with IH over the 3-year period from 2010 to 2013 was conducted. IH without identifiable cause was defined as idiopathic intracranial hypertension (IIH), whereas IH with identifiable pathologic aetiology was deemed secondary intracranial hypertension (SIH). A subset of patients with CN VI palsy was identified...
February 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27872047/detection-of-mild-papilloedema-in-posterior-uveitis-using-spectral-domain-optical-coherence-tomography
#12
A Philiponnet, C Vardanian, A Malcles, C Pochat, R Sallit, L Kodjikian
OBJECTIVE: To compare two methods for diagnosing mild papilloedema (PO) using peripapillary total retinal (PTR) and retinal nerve fibre layer (RNFL) thickness measurement by spectral domain optical coherence tomography (OCT) in patients suffering from posterior uveitis. METHODS: 17 eyes in 17 patients with PO caused by posterior uveitis, 15 eyes in 15 patients with uveitis but with no PO based on slit lamp analysis were studied. High-quality OCT fundus images were analysed and graded by three masked observers using the Modified Frisén Scale...
November 21, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27830325/efficacy-complications-and-cost-of-surgical-interventions-for-idiopathic-intracranial-hypertension-a-systematic-review-of-the-literature
#13
REVIEW
Aristotelis V Kalyvas, Mark Hughes, Christos Koutsarnakis, Demetrios Moris, Faidon Liakos, Damianos E Sakas, George Stranjalis, Ioannis Fouyas
BACKGROUND: To define the efficacy, complication profile and cost of surgical options for treating idiopathic intracranial hypertension (IIH) with respect to the following endpoints: vision and headache improvement, normal CSF pressure restoration, papilloedema resolution, relapse rate, operative complications, cost of intervention and quality of life. METHODS: A systematic review of the surgical treatment of IIH was carried out. Cochrane Library, MEDLINE and EMBASE databases were systematically searched from 1985 to 2014 to identify all relevant manuscripts written in English...
January 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/27743967/-idiopathic-intracranial-hypertension-experience-over-25-years-and-a-management-protocol
#14
Lorena Monge Galindo, Ruth Fernando Martínez, Cristina Fuertes Rodrigo, David Fustero de Miguel, Victoria Pueyo Royo, Juan Pablo García Iñiguez, Javier López-Pisón, José Luis Peña-Segura
INTRODUCTION: We present our experience on idiopathic intracranial hypertension (IIH), before and after the introduction of a specific diagnosis and management protocol. METHOD: A descriptive retrospective study was conducted on patients with IIH over a 25year period (1990-2015), comparing the last 7years (after introduction of the protocol) with the previous 18years. RESULTS: Among the 18,865 patients evaluated, there were 54 cases of IIH (29 infants and 25 children)...
October 13, 2016: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/27504325/a-prospective-study-of-the-clinical-profile-outcome-and-evaluation-of-d-dimer-in-cerebral-venous-thrombosis
#15
Venkatesh Thammishetti, Subrahmanyam Dharanipragada, Debdatta Basu, Ramesh Ananthakrishnan, Deepanjali Surendiran
INTRODUCTION: Cerebral Venous Thrombosis (CVT) is a well known disease with diverse clinical presentation and causes. With advances in neuroimaging and changing lifestyles, the clinical profile and causes of CVT are changing. D-dimer has been studied in early diagnosis of CVT with variable results. This prospective study was carried out to assess the clinical profile of CVT and role of D-dimer in diagnosis of CVT. AIM: To study various aspects of CVT and role of D-dimer...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27489047/papilloedema-secondary-to-oligodendroglioma
#16
REVIEW
David P Roncone
Oligodendrogliomas are rare slow-growing asymptomatic glial tumours that usually present in patients in their fourth to sixth decades of life. Neurological symptoms that may present include nausea, headache, vomiting, diplopia, confusion, focal weakness, numbness and seizures. The treatment of oligodendroglioma tumours is based on functional status classification, lumbar puncture, imaging of the head, tumour biopsy and genetic testing. Grades II and IV oligodendroglial tumours, which have co-deletion of the short arm of chromosome 1 (1p) and the long arm of chromosome 19 (19q) and mutations in isocitrate dehydrogenase, have the most favourable prognosis, as they respond well to neurosurgery and chemotherapy...
November 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/27430617/molecular-analysis-of-fgfr-2-and-associated-clinical-observations-in-two-chinese-families-with-crouzon-syndrome
#17
Ying Lin, Hongbin Gao, Siming Ai, Jacob V P Eswarakumar, Tao Li, Bingqian Liu, Hongye Jiang, Yuhua Liu, Xialin Liu, Yonghao Li, Yao Ni, Jiangna Chen, Zhuoling Lin, Xiaoling Liang, Chenjin Jin, Xinhua Huang, Lin Lu, Yizhi Liu
Crouzon syndrome, a dominantly inherited disorder and the most common type of craniosynostosis syndrome, is caused by mutations in the fibroblast growth factor receptor 2 (FGFR 2) gene, and characterized by craniosynostosis, shallow orbits, ocular proptosis, midface hypoplasia and a curved, beak‑like nose. The purpose of the present study was to investigate the fibroblast growth factor receptor 2 (FGFR 2) gene in two Chinese families with Crouzon syndrome and to characterize the associated clinical features...
September 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27341097/-the-current-diagnostic-possibilities-and-cooperation-of-oftalmologist-and-neurologist-concerning-in-patients-with-idiopatic-intracranial-hypertension
#18
Z Kasl, Rusňák Š, V Matušková, M Peterka, P Sobotka, N Jirásková
PURPOSE: The aim of this paper is to present the current possibilities in idiopatic intracranial hypertension (IIH) diagnostics. Optical coherence tomography belongs to these possibilities in last few years. The necesarry interdisciplinary co-operation of ophthalmologist and neurologist concerning in IIH patients is pointed out in the mentioned case reports. MATERIAL AND METHODS: The issue of diagnostics and care of IIH patients is presented in two case reports...
2016: Ceská a Slovenská Oftalmologie
https://www.readbyqxmd.com/read/27325302/an-olfactory-groove-schwannoma-with-a-pseudocyst-compressing-the-basal-ganglia-internal-capsule-and-optic-tracts
#19
Petr Liby, J Zamecnik, M Kyncl, M Tichy
INTRODUCTION: Olfactory groove schwannomas (OGSs) are extremely rare tumours, particularly in the paediatric population. CASE REPORT: A 13-year-old girl presented with two epileptic seizures, papilloedema and incomplete binasal quadrantanopia. Computed tomography (CT) and magnetic resonance imaging (MRI) demonstrated a large heterogeneously enhancing tumour of the anterior skull base with a prominent dorsal pseudocyst. Interestingly, the pseudocyst embraced the right ICA bifurcation and displaced the optic tracts, optic chiasm and optic nerves and the ipsilateral basal ganglia...
November 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27323559/clinical-features-and-outcome-analysis-of-intracranial-hydatid-cysts
#20
Muhammad Mukhtar Khan, Mewat Shah, Abdul Aziz Khan, Riaz ur Rehman, Shahid Ayub, Ayaz Ahmad, Atif Aman, Muhammad Ali Shah
BACKGROUND: Hydatid cyst of the brain is serious zoonotic parasitic infections which have profound health consequences if left untreated. The surgical excisions of the cysts are rewarding for both the patient the neurosurgeon. METHODS: The study was conducted prospectively at Department of Neurosurgery Hayatabad Medical Complex Peshawar from January 2013 to December 2014. Patients with a diagnosis of intracranial hydatid cysts were included, clinical and radiological features recorded, intervention and postoperative outcome were analysed...
January 2016: Journal of Ayub Medical College, Abbottabad: JAMC
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