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https://www.readbyqxmd.com/read/28525993/translation-and-validation-of-the-finnish-version-of-index-of-dental-anxiety-and-fear-idaf-4c-%C3%A2-among-dental-students
#1
Mimmi Tolvanen, Katri Puijola, Jason M Armfield, Satu Lahti
BACKGROUND: Dental fear accounts for 41% of the non-habitual dental attendance such as visiting only when in pain among adult Finns. Dentists should be able to recognize patients in risk for irregular attendance due to dental fear and measure their fear with valid and reliable instrument that capture the multidimensionality of dental fear. The study's aim was to translate the Index of Dental Anxiety and Fear (IDAF-4C+) into Finnish and test its reliability and validity. METHODS: The study population consisted of dental students in a Finnish university (n = 202)...
May 19, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28515070/even-mealtime-distribution-of-protein-intake-is-associated-with-greater-muscle-strength-but-not-with-3-y-physical-function-decline-in-free-living-older-adults-the-quebec-longitudinal-study-on-nutrition-as-a-determinant-of-successful-aging-nuage-study
#2
Samaneh Farsijani, Hélène Payette, José A Morais, Bryna Shatenstein, Pierrette Gaudreau, Stéphanie Chevalier
Background: Functional status declines with aging, thus impeding autonomy. Recently, a more even mealtime distribution of dietary protein was positively associated with muscle mass, but the relation of this distribution to physical performance remains unknown.Objective: We examined the relation between mealtime protein-intake distribution and physical performance and its 3-y decline in community-dwelling older adults.Design: Three-year follow-up data from 827 men and 914 women (67-84 y) in the longitudinal study on nutrition and aging [Quebec longitudinal study on Nutrition as a Determinant of Successful Aging (NuAge study); Quebec, Canada] were analyzed...
May 17, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28511726/executive-functioning-in-pedophilia-and-child-sexual-offending
#3
Claudia Massau, Gilian Tenbergen, Christian Kärgel, Simone Weiß, Hannah Gerwinn, Alexander Pohl, Till Amelung, Sebastian Mohnke, Jonas Kneer, Matthias Wittfoth, Inka Ristow, Kolja Schiltz, Klaus M Beier, Jorge Ponseti, Martin Walter, Tillmann H C Kruger, Henrik Walter, Boris Schiffer
OBJECTIVES: Pedophilia (P) is a psychiatric disease associated with sexual attraction toward children and often accompanied by child sexual offending (CSO). Consequently, it is important to address the understanding of executive dysfunctions that may increase the probability of CSO. Moreover, this research field has been lacking to disentangle executive deficits associated with pedophilia (as a deviant sexual preference) from those associated with CSO (as a deviant sexual behavior). METHODS: The German multi-sided research network NeMUP offers the opportunity to overcome these limitations...
May 17, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28506980/sex-differences-in-trajectories-of-risk-after-rehospitalization-for-heart-failure-acute-myocardial-infarction-or-pneumonia
#4
Rachel P Dreyer, Kumar Dharmarajan, Angela F Hsieh, John Welsh, Li Qin, Harlan M Krumholz
BACKGROUND: Women have an increased risk of rehospitalization in the immediate postdischarge period; however, few studies have determined how readmission risk dynamically changes on a day-to-day basis over the full year after hospitalization by sex and how these differences compare with the risk for mortality. METHODS AND RESULTS: We identified >3 000 000 hospitalizations of patients with a principal discharge diagnosis of heart failure, acute myocardial infarction, or pneumonia and estimated sex differences in the daily risk of rehospitalization/death 1 year after discharge from a population of Medicare fee-for-service beneficiaries aged 65 years and older...
May 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28493484/cytoplasmic-overexpression-of-rna-binding-protein-hur-is-a-marker-of-poor-prognosis-in-meningioma-and-hur-knockdown-decreases-meningioma-cell-growth-and-resistance-to-hypoxia
#5
Guillaume Gauchotte, Sébastien Hergalant, Charlène Vigouroux, Jean-Matthieu Casse, Rémi Houlgatte, Tony Kaoma, Déborah Helle, Lydia Brochin, Fabien Rech, Matthieu Peyre, François Labrousse, Laurent Vallar, Jean-Louis Gueant, Jean-Michel Vignaud, Shyue-Fang Battaglia-Hsu
HuR regulates cytoplasmic mRNA stability and translatability, and the HuR expression level has been shown to correlate with poor disease outcome in several cancer types; however, the prognostic value and potential pro-oncogenic properties of HuR in meningioma remain unclear. Thus, in the present study we analyzed 85 meningioma tissue samples to establish the relationship between HuR expression, tumor-cell proliferation, and/or patient survival. In addition, we examined the anti-proliferative effects of HuR knockdown in two meningioma cell lines (IOMM-Lee and Ben-Men1), and conducted transcriptome-wide analyses (IOMM-Lee cells) to elucidate the molecular consequences of HuR knockdown...
May 11, 2017: Journal of Pathology
https://www.readbyqxmd.com/read/28492924/handheld-reflectance-confocal-microscopy-for-the-detection-of-recurrent-extramammary-paget-disease
#6
Oriol Yélamos, Brian P Hibler, Miguel Cordova, Travis J Hollmann, Kivanc Kose, Michael A Marchetti, Patricia L Myskowski, Melissa P Pulitzer, Milind Rajadhyaksha, Anthony M Rossi, Manu Jain
Importance: Extramammary Paget disease (EMPD) is commonly refractory to surgical and nonsurgical therapies. Identifying recurrent or persistent EMPD is challenging because the disease is multifocal, and multiple blind scouting biopsies are usually performed in this setting. Handheld reflectance confocal microscopy (HRCM) has been used to diagnose and map primary EMPD and therefore may be used to identify EMPD recurrences. Objective: To evaluate HRCM's diagnostic accuracy in the setting of recurrent or persistent EMPD as well as its potential diagnostic pitfalls...
May 10, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28490561/four-year-nationwide-incidence-of-retinitis-pigmentosa-in-south-korea-a-population-based-retrospective-study-from-2011-to-2014
#7
Tyler Hyungtaek Rim, Hye Won Park, Dong Wook Kim, Eun Jee Chung
OBJECTIVE: To determine the incidence of retinitis pigmentosa (RP) in South Korea. DESIGN: Nationwide, population-based retrospective study. SETTING: Census population of South Korea PARTICIPANTS: This study involved the entire population of South Korea (n=47 990 761). Patients confirmed as having RP by an ophthalmologist from 1 January 2011 to 31 December 2014 were included. PRIMARY OUTCOME MEASURE: The average incidence of RP during the 4-year study period was estimated using population data from the 2010 Korean census...
May 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28458876/thymoma-world-health-organization-type-b3-with-neuroendocrine-differentiation-in-multiple-endocrine-neoplasia-type-1
#8
Masaki Tomita, Nobuhiko Ichiki, Takanori Ayabe, Hiroyuki Tanaka, Hiroaki Kataoka, Kunihide Nakamura
Thymic epithelial tumors occur in 1-5% of patients with multiple endocrine neoplasia type 1 (MEN 1). Majority of these thymic epithelial tumors are thymic carcinoids and patients with thymoma in MEN 1 is rare. Furthermore, thymoma with neuroendocrine differentiation was also rarely reported. Herein, we report a 68-year-old man having type B3 thymoma with neuroendocrine differentiation in MEN 1 and to the best of our knowledge this is the first such case ever reported.
April 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28455835/surgical-approaches-in-hereditary-endocrine-tumors
#9
REVIEW
Maurizio Iacobone, Marilisa Citton, Giovanni Viel, Donatella Schiavone, Francesca Torresan
Endocrine tumors of thyroid, adrenal and parathyroid glands may be due to germline and inheritable mutations in 5-30% of patients. Medullary Thyroid Carcinoma, Pheochromocytoma, Paraganglioma, and Familial Primary Hyperparathyroidism are the most frequent entity. Hereditary endocrine tumors usually have a suggestive familial history; they occur earlier than sporadic variants, are multifocal, and have increased recurrence rates. They may be present as isolated variant or associated to other neoplasms in a syndromic setting...
April 28, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28455148/morphological-suitability-for-endovascular-repair-non-intervention-rates-and-operative-mortality-in-women-and-men-assessed-for-intact-abdominal-aortic-aneurysm-repair-systematic-reviews-with-meta-analysis
#10
Pinar Ulug, Michael J Sweeting, Regula S von Allmen, Simon G Thompson, Janet T Powell
BACKGROUND: Prognosis for women with abdominal aortic aneurysm might be worse than the prognosis for men. We aimed to systematically quantify the differences in outcomes between men and women being assessed for repair of intact abdominal aortic aneurysm using data from study periods after the year 2000. METHODS: In these systematic reviews and meta-analysis, we identified studies (randomised, cohort, or cross-sectional) by searching MEDLINE, Embase, CENTRAL, and grey literature published between Jan 1, 2005, and Sept 2, 2016, for two systematic reviews and Jan 1, 2009, and Sept 2, 2016, for one systematic review...
April 25, 2017: Lancet
https://www.readbyqxmd.com/read/28449358/incident-rate-and-risk-factors-for-tuberculosis-among-patients-with-type-2-diabetes-retrospective-cohort-study-in-shanghai-china
#11
Hanbi Qiu, Yan Shi, Yanyun Li, Xin Shen, Rui Li, Qundi Yang, Qichao Pan, Fei Yan
OBJECTIVE: To examine the incident rate of tuberculosis (TB) and its associates among adults with type 2 diabetes in Shanghai, China. METHODS: We conducted a retrospective cohort study among 170,399 type 2 diabetes patients aged ≥18 years who were registered in Shanghai Community-Based Diabetes Management System between 2004 and 2009. Their TB status was tracked until December 31, 2014. Cox regression was performed to identify the risk factors for TB RESULTS: We documented 785 new TBcases during 654,977 person-years of follow-up...
April 27, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28441430/short-telomere-length-is-associated-with-renal-impairment-in-japanese-subjects-with-cardiovascular-risk
#12
Kazuo Eguchi, Lawrence S Honig, Joseph H Lee, Satoshi Hoshide, Kazuomi Kario
INTRODUCTION: Short telomere length has been suggested to be associated with atherosclerotic changes in Western populations. We examined the relationships between leukocyte telomere length and cardiovascular and renal function in a Japanese cohort. PARTICIPANTS AND METHODS: We enrolled 770 subjects who each had at least one cardiovascular risk factor. The mean age was 59.5 ± 12.2 years; mean BMI was 25.1 ± 4.6 kg/m2. We measured leukocyte telomere length (LTL) by quantitative PCR (T/S ratio), and measured other biomarkers from blood and urine samples...
2017: PloS One
https://www.readbyqxmd.com/read/28409509/fitness-can-be-a-determinant-of-arterial-stiffness-in-healthy-adult-men-a-cross-sectional-study
#13
Jin-Wook Chung, Mi-Lyang Kim, Youngsoo Jin, Yonghwan Kim, Jeeyoung Hong
BACKGROUND: Fitness is known to influence arterial stiffness. This study aimed to assess differences in cardiorespiratory endurance, muscular strength, and flexibility according to arterial stiffness, based on sex and age. METHODS: We enrolled 1,590 healthy adults (men: 1,242, women: 348) who were free of metabolic syndrome. We measured cardiorespiratory endurance in an exercise stress test on a treadmill, muscular strength by a grip test, and flexibility by upper body forward-bends from a standing position...
April 13, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28406897/changes-in-the-living-arrangement-and-risk-of-stroke-in-japan-does-it-matter-who-lives-in-the-household-who-among-the-family-matters
#14
MULTICENTER STUDY
Ehab Salah Eshak, Hiroyasu Iso, Kaori Honjo, Ai Noda, Norie Sawada, Shoichiro Tsugane
Previous studies have suggested associations of family composition with morbidity and mortality; however, the evidence of associations with risk of stroke is limited. We sought to examine the impact of changes in the household composition on risk of stroke and its types in Japanese population. Cox proportional hazard modelling was used to assess the risk of incident stroke and stroke types within a cohort of 77,001 Japanese men and women aged 45-74 years who experienced addition and/or loss of family members [spouse, child(ren), parent(s) and others] to their households over a five years interval (between 1990-1993 and 1995-1998)...
2017: PloS One
https://www.readbyqxmd.com/read/28396557/finding-sexual-partners-online-prevalence-and-associations-with-sexual-behaviour-sti-diagnoses-and-other-sexual-health-outcomes-in-the-british-population
#15
Melissa Cabecinha, Catherine H Mercer, Kirsten Gravningen, Catherine Aicken, Kyle G Jones, Clare Tanton, Kaye Wellings, Pam Sonnenberg, Nigel Field
OBJECTIVES: Online venues might facilitate sexual encounters, but the extent to which finding partners online is associated with sexual risk behaviour and sexual health outcomes is unclear. We describe use of the internet to find sexual partners in a representative sample in Britain. METHODS: The third National Survey of Sexual Attitudes and Lifestyles (Natsal-3) was a cross-sectional probability survey of 15 162 adults (aged 16-74 years) undertaken 2010-2012...
April 10, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28396101/the-effectiveness-of-treatments-for-androgenetic-alopecia-a-systematic-review-and-meta-analysis
#16
REVIEW
Areej Adil, Marshall Godwin
BACKGROUND: Androgenetic alopecia, or male pattern hair loss, is a hair loss disorder mediated by dihydrotestosterone, the potent form of testosterone. Currently, minoxidil and finasteride are Food and Drug Administration (FDA)-approved, and HairMax LaserComb, which is FDA-cleared, are the only treatments recognized by the FDA as treatments of androgenetic alopecia. OBJECTIVE: This systematic review and meta-analysis assesses the efficacy of nonsurgical treatments of androgenetic alopecia in comparison to placebo for improving hair density, thickness, growth (defined by an increased anagen:telogen ratio), or subjective global assessments done by patients and investigators...
April 7, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28392345/lifestyle-and-physiological-factors-associated-with-facial-wrinkling-in-men-and-women
#17
Merel A Hamer, Luba M Pardo, Leonie C Jacobs, M Arfan Ikram, Joop S Laven, Manfred Kayser, Loes M Hollestein, David A Gunn, Tamar Nijsten
Facial wrinkling is one of the most notable signs of skin aging. Men and women show different wrinkling patterns yet the lifestyle and physiological factors underlying these sex-specific patterns are relatively unknown. Here, we investigated sex-specific determinants for facial wrinkles. Wrinkle area was quantified digitally using facial photographs of 3,831 north-western Europeans (51-98 years, 58% female). Effect estimates from multivariable linear regressions are presented as the percentage difference in the mean value of wrinkle area per unit increase of a determinant (%Δ)...
April 6, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28391413/self-expanding-metal-stents-improve-swallowing-and-maintain-nutrition-during-neoadjuvant-therapy-for-esophageal-cancer
#18
Zachary L Smith, Jason E Gonzaga, George B Haasler, Elizabeth M Gore, Kulwinder S Dua
BACKGROUND: Patients with locally advanced esophageal cancer can have significant dysphagia. Nutritional support during neoadjuvant therapy is often delivered via nasoenteric or percutaneous feeding tubes. These approaches do not allow for per-oral feeding. AIMS: Evaluate the safety and efficacy of fully covered self-expanding metal esophageal stents for nutritional support during neoadjuvant therapy. METHODS: This was a pilot, prospective study at a single tertiary center...
April 8, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28376197/kinetics-of-the-human-papillomavirus-type-16-e6-antibody-response-prior-to-oropharyngeal-cancer
#19
Aimée R Kreimer, Mattias Johansson, Elizabeth L Yanik, Hormuzd A Katki, David P Check, Krystle A Lang Kuhs, Martina Willhauck-Fleckenstein, Dana Holzinger, Allan Hildesheim, Ruth Pfeiffer, Craig Williams, Neal D Freedman, Wen-Yi Huang, Mark P Purdue, Angelika Michel, Michael Pawlita, Paul Brennan, Tim Waterboer
Background: In a European cohort, it was previously reported that 35% of oropharyngeal cancer (OPC) patients were human papillomavirus type-16 (HPV16) seropositive up to 10 years before diagnosis vs 0.6% of cancer-free controls. Here, we describe the kinetics of HPV16-E6 antibodies prior to OPC diagnosis. Methods: We used annual serial prediagnostic blood samples from the PLCO Cancer Screening Trial. Antibodies to HPV were initially assessed in prediagnostic blood drawn at study enrollment from 198 incident head and neck cancer patients (median years to cancer diagnosis = 6...
August 1, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/28369902/oral-health-behavior-and-factors-associated-with-poor-oral-status-in-qatar-results-from-a-national-health-survey
#20
Sohaila Cheema, Patrick Maisonneuve, Mohamed Hamad Al-Thani, Al Anoud Mohammed Al-Thani, Amit Abraham, Ghanim Ali Al-Mannai, Abdulla Asad Al-Emadi, Walaa Fattah Al-Chetachi, Badria Ali Almalki, Shams Eldin Ali Hassan Khalifa, Ahmad Omar Haj Bakri, Albert Lowenfels, Ravinder Mamtani
OBJECTIVES: Oral health is a crucial determinant of quality of life. We aimed to determine oral health condition and factors associated with poor oral status in the adult national population of Qatar. METHODS: We used data from the World Health Organization supported STEPS (STEPwise approach to Surveillance) Survey conducted by the Supreme Council of Health, Qatar in 2012. A total of 2,496 Qataris (1,053 men, 1,443 women) answered the national survey. The Rao-Scott Chi-Square test was used to analyze oral health characteristics and multinomial logistic regression to assess risk factors...
March 28, 2017: Journal of Public Health Dentistry
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