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https://www.readbyqxmd.com/read/28327906/european-cancer-mortality-predictions-for-the-year-2017-with-focus-on-lung-cancer
#1
M Malvezzi, G Carioli, P Bertuccio, P Boffetta, F Levi, C La Vecchia, E Negri
Background: We predicted cancer mortality figures in the European Union (EU) for the year 2017 using most recent available data, with a focus on lung cancer. Materials and methods: We retrieved cancer death certification data and population figures from the World Health Organisation and Eurostat databases. Age-standardized (world standard population) rates were computed for France, Germany, Italy, Poland, Spain, the UK and the EU overall in 1970-2012. We obtained estimates for 2017 by implementing a joinpoint regression model...
February 21, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28325538/lifetime-risk-of-a-diagnosis-of-hiv-infection-in-the-united-states
#2
Kristen L Hess, Xiaohong Hu, Amy Lansky, Jonathan Mermin, Hildegard Irene Hall
PURPOSE: To estimate lifetime risk of receiving an HIV diagnosis in the United States if existing infection rates continue. METHODS: We used mortality, census, and HIV surveillance data for 2010 to 2014 to calculate age-specific probabilities of an HIV diagnosis. The probabilities were applied to a hypothetical cohort of 10 million live births to estimate lifetime risk. RESULTS: Lifetime risk was 1 in 68 for males and 1 in 253 for females...
February 21, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/28323985/utility-of-fdg-pet-imaging-for-risk-stratification-of-pancreatic-neuroendocrine-tumours-in-men-1
#3
E R Kornaczewski Jackson, O P Pointon, R Bohmer, J R Burgess
Context: Patients with Multiple Endocrine Neoplasia Type 1 (MEN 1) are at high risk of malignant pancreatic Neuroendocrine Tumours (pNETs). Structural imaging is typically used to screen for pNETs, but is suboptimal for stratifying malignant potential. Objective: To determine the utility of Fluorodeoxyglucose (18F) positron emission tomography/computed tomography (18F-FDG PET/CT) for predicting the malignant potential of pNETs in MEN 1. Design: Retrospective observational study...
March 7, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28300324/risk-of-stress-fracture-varies-by-race-ethnic-origin-in-a-cohort-study-of-1-3-million-u-s-army-soldiers
#4
Lakmini Bulathsinhala, Julie M Hughes, Craig J McKinnon, Joseph R Kardouni, Katelyn I Guerriere, Kristin L Popp, Ronald W Matheny, Mary L Bouxsein
Stress fractures (SF) are common and costly injuries in military personnel. Risk for SF has been shown to vary with race/ethnicity. Previous studies report increased SF risk in White and Hispanic Soldiers compared to Black soldiers. However, these studies did not account for the large ethnic diversity in the U.S. Military. PURPOSE: We aimed to identify differences in SF risk among racial/ethnic groups within the U.S. Army. METHODS: A retrospective cohort study was conducted using data from the Total Army Injury and Health Outcomes Database from 2001 until 2011...
March 16, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28285755/-the-human-and-economic-burden-of-cancer-in-france-in-2014-based-on-the-sniiram-national-database
#5
Philippe Tuppin, Laurence Pestel, Solène Samson, Anne Cuerq, Sébastien Rivière, Stéphane Tala, Pierre Denis, Jérôme Drouin, Claude Gissot, Christelle Gastaldi-Ménager, Anne Fagot-Campagna
INTRODUCTION: The national health insurance information system (Sniiram) can be used to estimate the national medical and economic burden of cancer. This study reports the annual rates, characteristics and expenditure of people reimbursed for cancer. METHODS: Among 57 million general health scheme beneficiaries (86% of the French population), people managed for cancer were identified using algorithms based on hospital diagnoses and full refund for long-term cancer...
March 9, 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/28251934/longitudinal-study-of-alcohol-consumption-and-hdl-concentrations-a-community-based-study
#6
Shue Huang, Junjuan Li, Gregory C Shearer, Alice H Lichtenstein, Xiaoming Zheng, Yuntao Wu, Cheng Jin, Shouling Wu, Xiang Gao
Background: In cross-sectional studies and short-term clinical trials, it has been suggested that there is a positive dose-response relation between alcohol consumption and HDL concentrations. However, prospective data have been limited.Objective: We sought to determine the association between total alcohol intake, the type of alcohol-containing beverage, and the 6-y (2006-2012) longitudinal change in HDL-cholesterol concentrations in a community-based cohort.Design: A total of 71,379 Chinese adults (mean age: 50 y) who were free of cardiovascular diseases and cancer and did not use cholesterol-lowering agents during follow-up were included in the study...
March 1, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28250991/polygamy-and-risk-of-coronary-artery-disease-in-men-undergoing-angiography-an-observational-study
#7
Amin Daoulah, Amir Lotfi, Mushabab Al-Murayeh, Salem Al-Kaabi, Salem M Al-Faifi, Osama E Elkhateeb, Mohamed N Alama, Ahmad S Hersi, Ciaran M Dixon, Waleed Ahmed, Mohamed Al-Shehri, Ali Youssef, Ahmed Moustafa Elimam, Ayman S Abougalambou, Waheed Murad, Alawi A Alsheikh-Ali
Epidemiologic evidence suggests a link between psychosocial risk factors such as marital status and coronary artery disease (CAD). Polygamy (multiple concurrent wives) is a distinct marital status practiced in many countries in Asia and the Middle East, but its association with CAD is not well defined. We conducted a multicenter, observational study of consecutive patients undergoing coronary angiography during the period from April 1, 2013, to March 30, 2014. Of 1,068 enrolled patients, 687 were married men...
2017: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/28249996/gender-inequalities-in-cardiovascular-risk-factor-assessment-and-management-in-primary-healthcare
#8
Karice K Hyun, Julie Redfern, Anushka Patel, David Peiris, David Brieger, David Sullivan, Mark Harris, Tim Usherwood, Stephen MacMahon, Marilyn Lyford, Mark Woodward
OBJECTIVES: To quantify contemporary differences in cardiovascular disease (CVD) risk factor assessment and management between women and men in Australian primary healthcare services. METHODS: Records of routinely attending patients were sampled from 60 Australian primary healthcare services in 2012 for the Treatment of Cardiovascular Risk using Electronic Decision Support study. Multivariable logistic regression models were used to compare the rate of CVD risk factor assessment and recommended medication prescriptions, by gender...
April 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28224442/report-of-the-primary-outcomes-for-gait-mechanics-in-men-of-the-acl-sports-trial-secondary-prevention-with-and-without-perturbation-training-does-not-restore-gait-symmetry-in-men-1-or-2-years-after-acl-reconstruction
#9
Jacob John Capin, Ryan Zarzycki, Amelia Arundale, Kathleen Cummer, Lynn Snyder-Mackler
BACKGROUND: Movement asymmetries during walking are common after anterior cruciate ligament (ACL) injury and reconstruction and may influence the early development of posttraumatic osteoarthritis. Preoperative neuromuscular training (like perturbation training, which is neuromuscular training requiring selective muscle activation in response to surface perturbations) improves gait asymmetries and functional outcomes among people who are ACL-deficient, but the effect of postoperative perturbation training on gait mechanics after ACL reconstruction is unknown...
February 21, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28218201/b-mode-and-contrast-enhancement-characteristics-of-small-nonincidental-neuroendocrine-pancreatic-tumors
#10
Barbara Braden, Christian Jenssen, Mirko D'Onofrio, Michael Hocke, Uwe Will, Kathleen Möller, Andre Ignee, Yi Dong, Xin-Wu Cui, Adrian Sãftoiu, Christoph F Dietrich
BACKGROUND AND OBJECTIVES: Imaging of the pancreas for detection of neuroendocrine tumors is indicated as surveillance in multiple endocrine neoplasia type 1 (MEN1) or if typical clinical symptoms combined with hormone production raise the suspicion of a neuroendocrine tumor. Endoscopic ultrasound (EUS) is considered the best imaging modality to detect small pancreatic tumors. However, little is known about how small pancreatic neuroendocrine tumors (pNETs) present on EUS. PATIENTS AND METHODS: In this multicenter study, we retrospectively analyzed the endosonographic characteristics of small pNETs which had been detected due to typical biochemistry and clinical symptoms or during surveillance of MEN 1...
January 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28194508/open-reduction-and-internal-fixation-for-intraarticular-fracture-of-metacarpal-head
#11
Jun-Ku Lee, Yong-Gil Jo, Ji-Woong Kim, Yun Seong Choi, Soo-Hong Han
Intraarticular fracture of the metacarpophalangeal (MP) joint presents complex problems related to the sophisticated functional aspects of the hand. Injury to the metacarpal head may have a severe effect on hand function but few studies have investigated the management of this condition. In this study, we applied open reduction and internal fixation for the displaced fracture of the metacarpal head and report the clinical and radiographic outcomes of our experience. Thirteen patients (12 men, 1 woman; mean age 21 years) were included in this study, and medical records and radiographs were reviewed retrospectively...
February 13, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28193677/sex-differences-in-the-clinical-impact-of-high-platelet-reactivity-after-percutaneous-coronary-intervention-with-drug-eluting-stents-results-from-the-adapt-des-study-assessment-of-dual-antiplatelet-therapy-with-drug-eluting-stents
#12
Jennifer Yu, Roxana Mehran, Usman Baber, Sze-Yuan Ooi, Bernhard Witzenbichler, Giora Weisz, Michael J Rinaldi, Franz-Josef Neumann, D Christopher Metzger, Timothy D Henry, David A Cox, Peter L Duffy, Ernest L Mazzaferri, Bruce R Brodie, Thomas D Stuckey, Akiko Maehara, Ke Xu, Ori Ben-Yehuda, Ajay J Kirtane, Gregg W Stone
BACKGROUND: Sex differences in the outcomes after percutaneous coronary intervention with drug-eluting stents and in the response to clopidogrel therapy have been reported; however, the differential risk of high platelet reactivity (HPR) on clopidogrel in women versus men is unknown. METHODS AND RESULTS: We compared 8448 patients enrolled in the ADAPT-DES study (Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents) according to sex and the presence/absence of HPR on clopidogrel (defined as P2Y12 reactivity units >208)...
February 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28166296/incidence-of-urinary-retention-during-treatment-with-single-tablet-combinations-of-solifenacin-tamsulosin-ocas%C3%A2-for-up-to-1-year-in-adult-men-with-both-storage-and-voiding-luts-a-subanalysis-of-the-neptune-neptune-ii-randomized-controlled-studies
#13
Marcus J Drake, Matthias Oelke, Robert Snijder, Monique Klaver, Klaudia Traudtner, Karin van Charldorp, Dominique Bongaerts, Philip Van Kerrebroeck
INTRODUCTION: The emergence of urinary retention (UR), specifically acute urinary retention (AUR), has been a concern when treating men with lower urinary tract symptoms (LUTS) with antimuscarinic drugs. MATERIALS AND METHODS: In NEPTUNE (12-week, double-blind), men (≥45 years) with LUTS were randomized to receive tamsulosin oral-controlled absorption system (TOCAS) 0.4 mg, fixed-dose combination (FDC) of solifenacin (Soli) 6 mg + TOCAS 0.4 mg, FDC Soli 9 mg + TOCAS 0...
2017: PloS One
https://www.readbyqxmd.com/read/28159391/socioeconomic-status-and-the-25%C3%A2-%C3%A3-%C3%A2-25-risk-factors-as-determinants-of-premature-mortality-a-multicohort-study-and-meta-analysis-of-1%C3%A2-7-million-men-and-women
#14
Silvia Stringhini, Cristian Carmeli, Markus Jokela, Mauricio Avendaño, Peter Muennig, Florence Guida, Fulvio Ricceri, Angelo d'Errico, Henrique Barros, Murielle Bochud, Marc Chadeau-Hyam, Françoise Clavel-Chapelon, Giuseppe Costa, Cyrille Delpierre, Silvia Fraga, Marcel Goldberg, Graham G Giles, Vittorio Krogh, Michelle Kelly-Irving, Richard Layte, Aurélie M Lasserre, Michael G Marmot, Martin Preisig, Martin J Shipley, Peter Vollenweider, Marie Zins, Ichiro Kawachi, Andrew Steptoe, Johan P Mackenbach, Paolo Vineis, Mika Kivimäki
BACKGROUND: In 2011, WHO member states signed up to the 25 × 25 initiative, a plan to cut mortality due to non-communicable diseases by 25% by 2025. However, socioeconomic factors influencing non-communicable diseases have not been included in the plan. In this study, we aimed to compare the contribution of socioeconomic status to mortality and years-of-life-lost with that of the 25 × 25 conventional risk factors. METHODS: We did a multicohort study and meta-analysis with individual-level data from 48 independent prospective cohort studies with information about socioeconomic status, indexed by occupational position, 25 × 25 risk factors (high alcohol intake, physical inactivity, current smoking, hypertension, diabetes, and obesity), and mortality, for a total population of 1 751 479 (54% women) from seven high-income WHO member countries...
February 1, 2017: Lancet
https://www.readbyqxmd.com/read/28151744/childhood-cognitive-ability-and-incident-dementia-the-1932-scottish-mental-survey-cohort-into-their-tenth-decade
#15
Tom C Russ, Jean Hannah, G David Batty, Christopher C Booth, Ian J Deary, John M Starr
BACKGROUND: The prevention of dementia is a global priority but its etiology is poorly understood. Early life cognitive ability has been linked to subsequent dementia risk but studies to date have been small and none has examined sex differences. METHODS: In the 1932 Scottish Mental Survey cohort, we related intelligence test scores at age 11 years in 16,370 boys and 16,097 girls (born in 1921) to incident dementia aged ≥65 years as ascertained using probabilistic linkage to electronic health records up to the age of 92 years (1231 cases in men, 2163 in women; median follow up 15 years)...
January 30, 2017: Epidemiology
https://www.readbyqxmd.com/read/28134665/association-of-epithelial-atypia-with-recurrence-after-surgical-excision-in-conjunctival-papilloma
#16
Hiroyuki Yazu, Murat Dogru, Jun Miyauchi, Yoichi Tanaka, Takefumi Yamaguchi, Seika Den, Yoshiyuki Satake, Kazuo Tsubota, Jun Shimazaki
PURPOSE: To investigate the association between recurrence of conjunctival papillomas and presence of atypical epithelial changes in patients undergoing surgical excision for conjunctival papilloma. METHODS: We retrospectively reviewed 1,195 ophthalmic pathology specimens from 2004 to 2014 at Ichikawa General Hospital. Pathologic specimens of 5 patients with a final diagnosis of "conjunctival papilloma" were stained with hematoxylin-eosin, Ki 67, p53, human papillomavirus (HPV) 16 and 18 antibodies...
January 27, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28126416/cytotoxic-pregnane-steroids-from-the-seeds-of-cipadessa-baccifera-roth-miq
#17
Lei Zhao, Ping Zhang, Xiao-Jie Su, Bing Zhang
A chemical investigation of the 80% ethanol extract of the seeds of Cipadessa baccifera (Roth.) Miq. led to the isolation of five new pregnane steroids, 17α,18,20S-trihydroxy-pregn-4-en-3,16-dione (1), 18-hydoxy-pregn-4,17(20)-trans-dien-3,16-dione (2), 3β,18-dihydroxy-pregn-5,17(20)-trans-dien-16-one (3), 2α,3β,4β,18-tetrahydroxy-pregn-5,17(20)-trans-dien-16-one (4), and 2α,3β,4β,17α,18,20S-hexahydroxy-pregn-5-en-16-one (5), along with two known compounds, 17α,20S-dihydroxy-pregn-4-en-3,16-dione (6) and 3β-hydroxy-pregn-5,17-dien-16-one (7)...
March 2017: Fitoterapia
https://www.readbyqxmd.com/read/28122172/association-of-type-2-diabetes-and-inflammatory-marker-with-incident-bone-fracture-among-a-japanese-cohort
#18
Yasuyuki Mitama, Saeko Fujiwara, Masayasu Yoneda, Sakurako Kira, Nobuoki Kohno
AIMS/INTRODUCTION: There are various causes of incident bone fracture. Not only aging, low bone mineral density and history of previous fracture, but also diabetes mellitus (DM) and inflammation are regarded as the risk of fracture. The purpose of this study is to verify the association of glycemic control or one inflammatory marker with incident fracture in a large-scale Japanese cohort. MATERIALS AND METHODS: This study was conducted at the Hiroshima Atomic Bomb Casualty Council and included 6,556 participants (2,785 men and 3,771 women, age 55-87) who underwent annual health examination followed for 7...
January 25, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28122035/assessing-sex-differences-in-the-risk-of-cardiovascular-disease-and-mortality-per-increment-in-systolic-blood-pressure-a-systematic-review-and-meta-analysis-of-follow-up-studies-in-the-united-states
#19
Yu-Chung Wei, Nysia I George, Ching-Wei Chang, Karen A Hicks
In the United States (US), cardiovascular (CV) disease accounts for nearly 20% of national health care expenses. Since costs are expected to increase with the aging population, informative research is necessary to address the growing burden of CV disease and sex-related differences in diagnosis, treatment, and outcomes. Hypertension is a major risk factor for CV disease and mortality. To evaluate whether there are sex-related differences in the effect of systolic blood pressure (SBP) on the risk of CV disease and mortality, we performed a systematic review and meta-analysis...
2017: PloS One
https://www.readbyqxmd.com/read/28110858/-the-prevalence-of-diagnosed-and-undiagnosed-hepatitis-c-virus-infection-in-navarra-spain-2014-2016
#20
Aitziber Aguinaga, Jorge Díaz-González, Alejandra Pérez-García, Laura Barrado, Iván Martínez-Baz, Itziar Casado, Regina Juanbeltz, Carmen Ezpeleta, Jesús Castilla
OBJECTIVE: To estimate the prevalence of hepatitis C virus (HCV) infection in Navarra, Spain, as well as to distinguish between diagnosed and undiagnosed infections. METHODS: A study was conducted on patients scheduled for surgery unrelated to HCV infection. They were all tested for HCV antibodies, under a routine scheme, from January 2014 to September 2016. Patients with a positive result by enzyme immunoassay were confirmed using immunoblot and/or HCV-RNA. Previous laboratory results were also taken into account...
January 19, 2017: Enfermedades Infecciosas y Microbiología Clínica
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