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Margalida Gili, Emilio López-Navarro, Adoración Castro, Clara Homar, Capilla Navarro, Mauro García-Toro, Javier García-Campayo, Miquel Roca
BACKGROUND: Economic crises have a negative effect on mental health. Little evidence has been published on the impact of economic downturns on male and female. The aim of the study was to analyze gender differences in specific mental disorders in primary care during the current economic recession in Spain. METHOD: A total of 7,914 patients in 2006 and 5,876 patients in 2010 were recruited to collect sociodemographic data and the Primary Care Evaluation of Mental Disorders...
November 2016: Psicothema
L Prentice, H K Muller, J R Burgess
No abstract text is available yet for this article.
February 2016: Pathology
D Donegan, N Singh Ospina, R Rodriguez-Gutierrez, Z Al-Hilli, G B Thompson, B L Clarke, W F Young
BACKGROUND: In patients with multiple endocrine neoplasia type 1 (MEN-1), pancreaticoduodenal (PD) neuroendocrine tumors (NETs) are associated with early mortality, yet, the best treatment strategy, remains uncertain. AIM: To assess patient important outcomes (mortality and metastasis) of PD NETs and predictors of outcomes in patients with MEN-1. METHODS: Retrospective cohort of patients with MEN-1 who attended the Mayo Clinic, Rochester, MN from 1997-2014...
October 21, 2016: Clinical Endocrinology
Asbjørn Støylen, Harald E Mølmen, Håvard Dalen
BACKGROUND: We aimed to study left ventricular (LV) geometry assessed by length (LVWL), external diameter (LVEDD) and relative wall thickness (RWT) in relation to age, body size and gender in healthy individuals. METHODS: 1266 individuals underwent echocardiography in the Nord-Trøndelag Health Study (HUNT3), Norway. Septum thickness (IVS), posterior wall thickness (LVPWd) and end-diastolic internal diameter (LVIDD) were measured in M-mode, and LVEDD was calculated as the sum...
2016: Open Heart
Tyra Dark, Heather A Flynn, George Rust, Heidi Kinsell, Jeffrey S Harman
OBJECTIVE: The purpose of this study was to describe the epidemiology of anxiety-related emergency department (ED) visits in the United States and assess the care provided during those visits. METHODS: Data from the 2009-2011 National Hospital Ambulatory Medical Care Survey were used to identify all ED visits in which the patient received a primary anxiety diagnosis or declared anxiety as the reason for the visit (N=1,029). Patient characteristics, treatment provided, and dispositions of these nationally representative visits were assessed...
October 17, 2016: Psychiatric Services: a Journal of the American Psychiatric Association
R K Jain, T J Vokes
: Trabecular bone score, an indirect measure of bone structure, may differ between ethnicities. We found that African Americans had lower trabecular bone score than do whites referred for densitometry, even when controlling for age and abdominal soft tissue thickness. PURPOSE: Trabecular bone score (TBS), an indirect measure of bone structure, has been shown to predict fractures in predominantly white populations. Analysis of NHANES data revealed lower TBS in African Americans than in whites...
October 14, 2016: Osteoporosis International
Bianca Miarka, Katarzyna Sterkowicz-Przybycien, David H Fukuda
The purpose of the present study was to create a probabilistic neural network (PNN) to clarify the understanding of movement patterns in international judo competitions by gender. Analysis of 773 male and 638 female bouts was utilized to identify movements during the approach, gripping, attack (including biomechanical designations), groundwork, defense, and pause phases. PNN and χ(2) tests modeled and compared frequencies (p≤0.05). Women (mean[interquartile range]: 9.9[4;14]) attacked more than men (7.0[3;10]) while attempting a greater number of arm/leg lever (women: 2...
October 13, 2016: Motor Control
David Scott, Markus Seibel, Robert Cumming, Vasi Naganathan, Fiona Blyth, David G Le Couteur, David J Handelsman, Louise M Waite, Vasant Hirani
Body composition and muscle function have important implications for falls and fractures in older adults. We aimed to investigate longitudinal associations between sarcopenic obesity and its components with bone mineral density (BMD), and incident falls and fractures, in Australian community-dwelling older men. 1,486 men aged ≥70 years from the Concord Health and Ageing in Men Project (CHAMP) study were assessed at baseline (2005-2007), 2 year follow-up (2007-2009; N = 1,238), and 5 year follow-up (2010-2013; N = 861)...
October 13, 2016: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
Mar Ruperto, Guillermina Barril, Francisco J Sánchez-Muniz
Abdominal fat has been recognized as the most hormonally active tissue secreting a variety of adipocytokines and, therefore, potentially contributing to inflammation. The conicity index (Cindex) has been considered a valuable indicator of central obesity. This study aims to relate plasma concentrations of leptin, adiponectin, interleukin-6 (IL-6), and serum C-reactive protein (CRP) with Cindex values in hemodialysis (HD) patients. Cross-sectional study in 45 HD patients (55.6 % men; DM 20 %; mean age, 68...
October 13, 2016: Journal of Physiology and Biochemistry
Yuta Matsukuma, Kosuke Masutani, Shigeru Tanaka, Akihiro Tsuchimoto, Kiichiro Fujisaki, Kumiko Torisu, Ritsuko Katafuchi, Hideki Hirakata, Kazuhiko Tsuruya, Takanari Kitazono
Recently, low serum uric acid (SUA) levels and high SUA levels, have emerged as risk factors for cardiovascular disease, as well as for the incidence of acute kidney injury and chronic kidney disease (CKD). However, the effect of low SUA on the progression of CKD remains unclear. To evaluate the association between SUA and renal prognosis in patients with immunoglobulin A nephropathy (IgAN), one of the most common causes of CKD, we retrospectively followed 1218 patients who were diagnosed with primary IgAN by kidney biopsy between October 1979 and December 2010...
October 13, 2016: Hypertension Research: Official Journal of the Japanese Society of Hypertension
J A Van Heerden, J R Burger, J J Gerber
BACKGROUND: Prescribing for older patients is a well-recognised problem, and inappropriate items are prescribed frequently. Several tools and criteria are available to promote rational prescribing in older patients. OBJECTIVE: To determine the prevalence of potentially inappropriate prescriptions (PIPs) in older South African patients. METHODS: A retrospective drug utilisation review was conducted using medicine claims data over a 1-year period...
September 9, 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
Elsemiek M Engbers, Jorik R Timmer, Jan Paul Ottervanger, Mohamed Mouden, Siert Knollema, Pieter L Jager
The coronary artery calcium (CAC) score provides independent prognostic value on top of single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). We sought to determine whether the prognostic value of the CAC score in patients with normal SPECT MPI is gender specific. We studied 3,705 consecutive symptomatic patients without a history of coronary artery disease with normal SPECT MPI. All patients underwent concomitant CAC scoring, which was categorized as CAC score 0, 1 to 99, 100 to 399, 400 to 999, or ≥1,000...
August 30, 2016: American Journal of Cardiology
Fengyi Jin, Gail V Matthews, Andrew E Grulich
A systematic review was performed on the evidence of sexual transmission of hepatitis C virus (HCV) in gay and bisexual men (GBM). Studies conducted in industrialised countries and published in English from 2000 to 2015 with data on HCV in GBM were included. Pooled estimates of prevalence and incidence of HCV infection were stratified by study settings and participants' HIV status using random effect models. Case-series reports were summarised descriptively. Of the 38 cross-sectional studies, the pooled HCV prevalence was substantially higher in HIV-positive men (8...
October 7, 2016: Sexual Health
Manuel C D F Maia, Delmar Muniz Lourenço, Rachel Riechelmann
BACKGROUND: Approximately 10% of pancreatic neuroendocrine tumors (NET) are associated with familial syndromes, with the most common type being multiple endocrine neoplasia type 1 (MEN-1). However, the available evidence on how to treat NET comes from studies in sporadic NET. CASE REPORT: Here we report the case of a 51-year-old male patient with a metastatic MEN-1-associated pancreatic NET and hypercalcemia related to primary hyperparathyroidism and tumor-secreted parathyroid-related protein...
2016: Oncology Research and Treatment
Teri D Davis, Duncan G Campbell, Laura M Bonner, Cory R Bolkan, Andrew Lanto, Edmund F Chaney, Thomas Waltz, Kara Zivin, Elizabeth M Yano, Lisa V Rubenstein
OBJECTIVE: Depression is the most prevalent mental health condition in primary care (PC). Yet as the Veterans Health Administration increases resources for PC/mental health integration, including integrated care for women, there is little detailed information about depression care needs, preferences, comorbidity, and access patterns among women veterans with depression followed in PC. METHODS: We sampled patients regularly engaged with Veterans Health Administration PC...
September 30, 2016: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
Clothilde Hellouin-Desenne, Emma Marano, Xavier Devillard, Pascal Giraux
OBJECTIVE: To draw a questionnaire to estimate physical activity of adult foster home residents. To observe the physical activity's level and available time. To estimate the APA development's interest. MATERIAL/PATIENTS AND METHODS: We designed a questionnaire allowing to assess the physical activity in a population with motor deficiencies. It was tested among 12 healthy subjects and 25 adult foster home residents. The residents' stay at this foster home (FH) lasts between a few days and a few weeks...
September 2016: Annals of Physical and Rehabilitation Medicine
Sikarin Upala, Pattara Rattanawong, Wasawat Vutthikraivit, Anawin Sanguankeo
INTRODUCTION: There is inconclusive evidence whether osteoporosis increases risk of hearing loss in current literature. OBJECTIVE: We conducted this meta-analysis to determine whether there is an association between hearing loss and osteoporosis. METHODS: This systematic review and meta-analysis was conducted from the studies in MEDLINE, EMBASE, and LILACS. Osteoporosis was defined as having a bone mineral density (BMD) with a T-score of less than -2...
September 12, 2016: Brazilian Journal of Otorhinolaryngology
Siegal Sadetzki, Angela Chetrit, Michelle C Turner, Martie van Tongeren, Geza Benke, Jordi Figuerola, Sarah Fleming, Martine Hours, Laurel Kincl, Daniel Krewski, Dave McLean, Marie-Elise Parent, Lesley Richardson, Brigitte Schlehofer, Klaus Schlaefer, Maria Blettner, Joachim Schüz, Jack Siemiatycki, Elisabeth Cardis
The aim of the study was to examine associations between occupational exposure to metals and meningioma risk in the international INTEROCC study. INTEROCC is a seven-country population-based case-control study including 1906 adult meningioma cases and 5565 population controls. Incident cases were recruited between 2000 and 2004. A detailed occupational history was completed and job titles were coded into standard international occupational classifications. Estimates of mean workday exposure to individual metals and to welding fumes were assigned based on a job-exposure-matrix...
September 23, 2016: Journal of Neuro-oncology
Sanne Ae Peters, Ling Yang, Yu Guo, Yiping Chen, Zheng Bian, Iona Y Millwood, Shaojie Wang, Liqiu Yang, Yihe Hu, Jiaqiu Liu, Tao Wang, Junshi Chen, Richard Peto, Liming Li, Mark Woodward, Zhengming Chen
BACKGROUND: Women's parity has been associated with risk of cardiovascular disease (CVD). It is unclear, however, whether it reflects biological effects of childbearing or uncontrolled socio-economic and lifestyle factors associated with childrearing. We assessed the association between number of children and incident CVD outcomes separately in women and men. METHODS: In 2004-08, the nationwide China Kadoorie Biobank recruited 0.5 million individuals aged 30-79 years from 10 diverse regions...
September 20, 2016: International Journal of Epidemiology
M E Mercado-Pimentel, S Igarashi, A M Dunn, M Behbahani, C Miller, C M Read, A Jacob
Activation of PKB/AKT signaling, which requires PDK1 and PDK2 function, drives Vestibular Schwannoma (VS) and meningioma growth. PDK2 function is defined as a molecule that phosphorylates AKT-Ser473. Integrin-Linked Kinase (ILK) functions as PDK2 in PKB/AKT activation in many cancers; therefore, we hypothesized that OSU-T315, a small molecule ILK inhibitor, will inhibit the ILK-PDK2 function in PKB/AKT signaling activation in VS and meningioma cell growth. OSU-T315 decreased cell viability at IC50 < 2μM in VS (HEI193) and meningioma (Ben-Men-1) cell lines, in primary cells at < 3...
2016: Austin J Med Oncol
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