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Optic disc edema

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https://www.readbyqxmd.com/read/28333858/immune-reconstitution-inflammatory-syndrome-causing-progressive-optic-nerve-edema-in-cryptococcal-meningitis
#1
Astrid C Werner, Laurel N Vuong, Thomas R Hedges, Caroline R Baumal
PURPOSE: To report an human immunodeficiency virus-positive patient undergoing therapy for cryptococcal meningitis who developed progressive optic disc edema that was steroid responsive. METHODS: Observational case report. RESULTS: One month after commencing antifungal treatment for cryptococcal meningitis, the patient developed bilateral, progressive, recurrent optic disc edema with subretinal fluid that coincided with initiation of highly active antiretroviral therapy and recovery of CD4 cell counts...
March 22, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28331457/visual-loss-retinal-hemorrhages-and-optic-disc-edema-resulting-from-thiamine-deficiency-following-bariatric-surgery-complicated-by-prolonged-vomiting
#2
Andrew W Lawton, Nicholas E Frisard
BACKGROUND: Vision loss resulting from thiamine deficiency is a recognized complication of bariatric surgery. Most patients with such vision loss have Wernicke encephalopathy with characteristic changes seen on neuroimaging. Other patients may have retinal hemorrhages, optic disc edema, and peripheral neuropathy without Wernicke encephalopathy. The risk for thiamine deficiency is potentiated by the presence of prolonged vomiting. CASE REPORT: A 37-year-old female presented with abrupt onset of vision loss and peripheral neuropathy following bariatric surgery...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/28299006/characteristics-of-macular-edema-in-behcet-disease-after-intravitreal-bevacizumab-injection
#3
Fariba Ghassemi, Sohrab Afshari Mirak, Hormoz Chams, Siamak Sabour, Mehdi Nilli Ahmadabadi, Fereidoun Davatchi, Farhad Shahram
PURPOSE: To investigate the effect of intravitreal bevacizumab (IVB) injection on macular edema (ME) secondary to Behcet's disease. METHODS: This prospective case series included 15 patients with bilateral ME due to Behcet's disease. Intravitreal bevacizumab was injected into the more severely involved eye; the contralateral eye was evaluated as the control. Patients were followed up with comprehensive ocular examination, optical coherence tomography, and fluorescein angiography (FA) for a minimum of 6 months by a single ophthalmologist...
January 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28284199/unilateral-malignant-optic-glioma-following-glioblastoma-multiforme-in-the-young-a-case-report-and-literature-review
#4
Chia-Ying Lin, Hsiu-Mei Huang
BACKGROUND: Malignant optic gliomas are rare, but they rapidly become lethal visual pathway tumors. We present the clinical course, treatment, and prognosis of a case of unilateral malignant optic glioma in a young man with a history of brain glioblastoma multiforme (GBM). CASE PRESENTATION: A 21-year-old man, who had GBM 7 years ago complained of a transient shadow in his vision and presented with normal visual acuity but optic disc edema and an enlarged blind spot in the right eye (oculus dexter, OD)...
March 11, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28243056/anti-vegf-treatment-and-peripheral-retinal-nonperfusion-in-patients-with-central-retinal-vein-occlusion
#5
Kaveh Abri Aghdam, Lukas Reznicek, Mostafa Soltan Sanjari, Annemarie Klingenstein, Marcus Kernt, Florian Seidensticker
PURPOSE: To evaluate the association between the size of peripheral retinal nonperfusion and the number of intravitreal ranibizumab injections in patients with treatment-naïve central retinal vein occlusion (CRVO). METHODS: Fifty-four patients with treatment-naïve CRVO and macular edema were included. Each patient underwent a full ophthalmologic examination including optical coherence tomography imaging and ultrawide-field fluorescein angiography. Monthly intravitreal ranibizumab injections were applied according to the recommendations of the German Ophthalmologic Society...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28196198/en-face-doppler-optical-coherence-tomography-measurement-of-total-retinal-blood-flow-in-diabetic-retinopathy-and-diabetic-macular-edema
#6
ByungKun Lee, Eduardo A Novais, Nadia K Waheed, Mehreen Adhi, Talisa E de Carlo, Emily D Cole, Eric M Moult, WooJhon Choi, Mark Lane, Caroline R Baumal, Jay S Duker, James G Fujimoto
Importance: Alterations in ocular blood flow play an important role in the pathogenesis and progression of diabetic retinopathy (DR). However, the measurement of retinal blood flow in clinical studies has been challenging. En face Doppler optical coherence tomography (OCT) provides an effective method for measuring total retinal blood flow (TRBF) in the clinic. Objective: To investigate TRBF in eyes with DR of varying severity, with or without diabetic macular edema (DME), using en face Doppler OCT...
March 1, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28168134/ocular-inflammatory-disease-as-a-predictor-for-in-hospital-mortality-in-patients-hospitalized-with-disseminated-tuberculosis
#7
Salil Mehta
AIM: To ascertain whether the presence of ocular inflammatory disease is a predictor for death in patients hospitalized with disseminated tuberculosis. METHODS: This is an IRB-approved retrospective study of patients admitted with a diagnosis of disseminated tuberculosis within a seven-year period (2002-2009). The following data was collected from each record: age, sex, details of previous surgeries or therapy, the findings of anterior segment examination, the findings of dilated indirect ophthalmoscopy, systemic findings, investigations done, treatment rendered, and final status (died or discharged)...
January 5, 2017: Curēus
https://www.readbyqxmd.com/read/28156180/diagnosis-of-optic-nerve-sheath-meningioma-during-optic-nerve-sheath-decompression
#8
Austin R Meeker, Melissa W Ko, Bryant P Carruth, Kenneth B Strumpf, Thomas A Bersani
Optic nerve sheath meningioma (ONSM) is typically diagnosed based on clinical suspicion and imaging characteristics and is most often treated with radiation. Historically, biopsy, optic nerve sheath decompression, and debulking surgeries have been avoided for fear of optic nerve vascular disruption and tumor spread into the orbit. This is a case of a 48-year-old man who presented with unilateral optic disc edema, declining visual acuity, and a visual field defect. Despite an initial improvement with acetazolamide, his vision subsequently worsened...
February 2017: Orbit
https://www.readbyqxmd.com/read/28131870/waiting-to-deliver-a-final-diagnosis
#9
Ali Mokhtarzadeh, Amanda Maltry, Collin McClelland
We report a patient with left eye positional transient visual obscurations, diplopia, a left afferent pupillary defect, and optic disk edema-all occurring during pregnancy. Noncontrast magnetic resonance imaging revealed an orbital mass encasing the optic nerve and extending through the superior orbital fissure into the cavernous sinus. An magnetic resonance imaging with gadolinium after parturition and strongly positive somatostatin receptor scintigraphy suggested the diagnosis of meningioma. Biopsy confirmed the diagnosis, and she was treated with CyberKnife stereotactic radiosurgery...
January 25, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28125740/retinal-nerve-fiber-layer-may-be-better-preserved-in-mog-igg-versus-aqp4-igg-optic-neuritis-a-cohort-study
#10
Hadas Stiebel-Kalish, Itay Lotan, Judith Brody, Gabriel Chodick, Omer Bialer, Romain Marignier, Michael Bach, Mark Andrew Hellmann
BACKGROUND: Optic neuritis (ON) in patients with anti-myelin oligodendrocyte glycoprotein (MOG)-IgG antibodies has been associated with a better clinical outcome than anti-aquaporin 4 (AQP4)- IgG ON. Average retinal nerve fiber layer thickness (RNFL) correlates with visual outcome after ON. OBJECTIVES: The aim of this study was to examine whether anti-MOG-IgG ON is associated with better average RNFL compared to anti-AQP4-IgG ON, and whether this corresponds with a better visual outcome...
2017: PloS One
https://www.readbyqxmd.com/read/28058166/imaging-methods-in-the-diagnosis-of-optic-disc-drusen
#11
REVIEW
Betül Tuğcu, Hakan Özdemir
Optic disc drusen (ODD) are benign congenital anomalies of the optic nerve characterized by calcified hyaline bodies. While superficial drusen can be diagnosed easily during fundus examination, detecting buried drusen requires the use of additional imaging methods such as B-scan ultrasonography (USG), fundus fluorescein angiography (FFA), computed tomography (CT) and fundus autofluorescence (FAF). ODD can be detected by USG with the presentation of highly reflective round structures. ODD appear as hyperautofluorescent areas on FAF and bright spots on CT scans...
October 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28058155/bilateral-papillophlebitis-in-a-patient-with-mutation-of-metilenetetrahydrofolate-reductase-enzyme
#12
Hüseyin Güzel, Banu Turgut Öztürk, Şansal Gedik, Berker Bakbak, Abdullah Beyoğlu, Nadir Koçak
Papillophlebitis is known as central retinal vein occlusion seen in young patients. It usually presents as unilateral optic disc edema with cotton wool spots and hemorrhage in the peripapillary region. As it may be due to many autoimmune and inflammatory causes, a thorough systemic evaluation of the patient is warranted. In this case report we describe a bilateral, simultaneous papillophlebitis case thought to be related to hyperhomocysteinemia secondary to C677T polymorphism of methylenetetrahyrofolate reductase enzyme...
August 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28045864/bilateral-central-retinal-vein-occlusions-in-a-young-patient-with-a-history-of-eosinophilic-pneumonia-and-thalamic-stroke
#13
Gina Yu, Peng Sun, Tavé van Zyl, Rachel Tandias, Jorge G Arroyo
PURPOSE: To describe a case of a central retinal vein occlusion in a young patient with a history of eosinophilic pneumonia. METHODS: A retrospective case report of a 45-year-old woman with acute painless vision loss for 9 days after multiple episodes of eosinophilic pneumonia and thalamic stroke. Fluorescein angiography, spectral domain optical coherence tomography, and clinical examination were performed. She was then treated with intravitreal bevacizumab and pan-retinal photocoagulations...
December 29, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28029908/pathology-of-ischemic-optic-neuropathy
#14
REVIEW
Hershel R Patel, Curtis E Margo
Ischemic optic neuropathy (ION) describes a state of hypoxic injury of the optic nerve. Clinically, ION is divided into anterior and posterior forms defined by the presence or absence of optic disc swelling, respectively. It is further classified as arteritic when secondary to vasculitis, and nonarteritic when not. The site of vascular occlusion for anterior ION from giant cell arteritis is the short posterior ciliary arteries, but mechanical vascular obstruction does not play a role in most nonarteritic cases...
January 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/27982219/nonarteritic-anterior-ischemic-optic-neuropathy-following-pars-plana-vitrectomy-for-macular-hole-treatment-case-report
#15
Leonardo Provetti Cunha, Luciana Virgínia Ferreira Costa Cunha, Carolina Ferreira Costa, Mário Luiz Ribeiro Monteiro
Herein, we report a case of nonarteritic anterior ischemic optic neuropathy (NAION) following uneventful pars plana vitrectomy for macular hole treatment. A 56-year-old previously healthy woman presented with a full-thickness macular hole in right eye (OD) and small cup-to-disc ratios in both eyes. Five days after surgery, she noticed sudden painless loss of vision in OD and was found to have an afferent pupillary defect and intraocular pressure of 29 mmHg. Fundus examination showed right optic disc edema and the resolution of a macular hole with an inferior altitudinal visual field defect...
September 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/27940011/pediatric-intracranial-hypertension
#16
REVIEW
Shawn C Aylward, Rachel E Reem
Primary (idiopathic) intracranial hypertension has been considered to be a rare entity, but with no precise estimates of the pediatric incidence in the United States. There have been attempts to revise the criteria over the years and adapt the adult criteria for use in pediatrics. The clinical presentation varies with age, and symptoms tending to be less obvious in younger individuals. In the prepubertal population, incidentally discovered optic disc edema is relatively common. By far the most consistent symptom is headache; other symptoms include nausea, vomiting tinnitus, and diplopia...
January 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/27938350/central-retinal-artery-occlusion-and-cerebral-infarction-associated-with-mycoplasma-pneumonia-infection-in-children
#17
Yunguang Bao, Xiaobing Li, Kaixuan Wang, Chan Zhao, Xiumei Ji, Mizu Jiang
BACKGROUND: Central retinal artery occlusion (CRAO) is an arterial ischemic stroke, rarely occurred in children accompanied with asymptomatic cerebral infarction and almost never involved in severe pneumonia related to Mycoplasma pneumonia infection. CASE PRESENTATION: An 8-year-old boy with severe pneumonia related to Mycoplasma pneumonia infection that developed loss of vision in the left eye on the 14(th) day. No light perception and no pupillary reaction to light were found in the left eye...
December 9, 2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27843238/optic-neuritis-with-secondary-retinal-venous-stasis-in-a-case-of-abdominal-tuberculosis
#18
Harshika Chawla, Vishal Vohra, Praveen Malik
The authors report a case of unilateral optic neuritis along with secondary retinal venous stasis in a patient diagnosed with abdominal tuberculosis. Patient presented with diminished visual acuity, colour perception and Marcus Gunn pupillary response, pointing towards optic nerve involvement. Associated findings of disc edema, dilated and tortuous veins, along with hemorrhages on disc and superotemporal quadrant made diagnosis of retinal venous stasis secondary to optic neuritis imperative. The visual outcome of the patient paralleled that expected with optic neuritis...
September 2016: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/27800278/orbital-metastasis-of-multiple-myeloma-case-report
#19
Mustafa Vatansever, Fatma Merve Bozkurt, Erdem Dinç, Eda Bengi Yılmaz, Erdinç Nayir, Ayşe Ayça Sarı, Özlem Yıldırım, Tuba Kara
A 68-year-old woman with a history of multiple myeloma presented to the clinic with pain and vision loss in her right eye. Proptosis was observed in her right eye and eye movements were restricted in all directions. Best corrected visual acuity was 3/10 in her right eye. On biomicroscopic examination, hyperemia and subconjunctival hemorrhage were present. Fundus examination of the right eye revealed optic disc edema and choroidal folds. In magnetic resonance imaging two orbital masses were detected. Based on the patient's history and ocular examination, we evaluated the masses as orbital metastasis of multiple myeloma...
June 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27769343/acute-myelogenous-leukemia-presenting-with-uveitis-optic-disc-edema-and-granuloma-annulare-case-report
#20
Kevin Shen, Stacy V Smith, Andrew G Lee
No abstract text is available yet for this article.
October 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
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