Lavoisiana Lacerda de Lucena, Alexandre Sérgio Silva, Rayner Anderson Ferreira do Nascimento, Darlene Camati Persuhn, Juliana Padilha Ramos Neves, Maria José Carvalho Costa, Dayana Joyce Marques Queiroz, Rafaela Lira Formiga Covalcanti de Lima, Raquel Patrícia Ataíde de Lima, Maria Paula de Paiva, Naila Francis Paulo de Oliveira, Maria da Conceição Rodrigues Gonçalves
Background: the biological activity of vitamin D depends on the activity of its receptor or VDR. On the other hand, the activity of this receptor is influenced by its state of methylation. The objective of this study was to verify if the BsmI polymorphism of the VDR gene influences its methylation profile in adolescents. Secondly, it was to verify if the status of some metabolic factors (oxidative stress, inflammation, lipid profile, and glycemia) in the serum, and gender-adjusted vitamin D levels are independent factors with an influence on the VDR methylation profile...
October 13, 2021: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral