keyword
https://read.qxmd.com/read/38455819/utility-of-ct-scan-in-detecting-bladder-involvement-among-patients-with-cervical-carcinoma
#21
JOURNAL ARTICLE
Rajni Agrawal, Ritika Agarwal
Background Cervical cancer is a widespread health issue in India, particularly affecting women as the second most common cancer. The burden of cervical cancer in the country necessitates accurate staging for treatment optimization. The revised International Federation of Gynecology and Obstetrics (FIGO) staging system is vital for this purpose, emphasizing the extent of parametrial and pelvic sidewall involvement. Cervical cancer's propensity to infiltrate neighboring pelvic organs, including the bladder, necessitates precise staging...
February 2024: Curēus
https://read.qxmd.com/read/38455095/advances-in-the-differentiation-of-pluripotent-stem-cells-into-vascular-cells
#22
REVIEW
Yi-Chang Jiao, Ying-Xin Wang, Wen-Zhu Liu, Jing-Wen Xu, Yu-Ying Zhao, Chuan-Zhu Yan, Fu-Chen Liu
Blood vessels constitute a closed pipe system distributed throughout the body, transporting blood from the heart to other organs and delivering metabolic waste products back to the lungs and kidneys. Changes in blood vessels are related to many disorders like stroke, myocardial infarction, aneurysm, and diabetes, which are important causes of death worldwide. Translational research for new approaches to disease modeling and effective treatment is needed due to the huge socio-economic burden on healthcare systems...
February 26, 2024: World Journal of Stem Cells
https://read.qxmd.com/read/38455071/risk-of-vaccine-preventable-diseases-in-uk-migrants-a-serosurvey-and-concordance-analysis
#23
JOURNAL ARTICLE
Mayuri Gogoi, Christopher A Martin, Paul W Bird, Martin J Wiselka, Judi Gardener, Kate Ellis, Valerie Renals, Adam J Lewszuk, Sally Hargreaves, Manish Pareek
BACKGROUND: Vaccine preventable diseases (VPDs) such as measles and rubella cause significant morbidity and mortality globally every year. The World Health Organization (WHO), reported vaccine coverage for both measles and rubella to be 71 % in 2019, indicating an immunity gap. Migrants in the EU/EEA may be at high risk of VPDs due to under-immunisation and poor living conditions. However, there are limited data on VPD seroprotection rates amongst migrants living in the United Kingdom (UK)...
2024: Journal of migration and health
https://read.qxmd.com/read/38454006/reservoir-rock-typing-assessment-in-a-coal-tight-sand-based-heterogeneous-geological-formation-through-advanced-ai-methods
#24
JOURNAL ARTICLE
Umar Ashraf, Wanzhong Shi, Hucai Zhang, Aqsa Anees, Ren Jiang, Muhammad Ali, Hassan Nasir Mangi, Xiaonan Zhang
Geoscientists now identify coal layers using conventional well logs. Coal layer identification is the main technical difficulty in coalbed methane exploration and development. This research uses advanced quantile-quantile plot, self-organizing maps (SOM), k-means clustering, t-distributed stochastic neighbor embedding (t-SNE) and qualitative log curve assessment through three wells (X4, X5, X6) in complex geological formation to distinguish coal from tight sand and shale. Also, we identify the reservoir rock typing (RRT), gas-bearing and non-gas bearing potential zones...
March 7, 2024: Scientific Reports
https://read.qxmd.com/read/38452979/biochemical-histological-and-transcriptional-response-of-intestines-in-litopenaeus-vannamei-under-chronic-zinc-exposure
#25
JOURNAL ARTICLE
Xianbin Su, Xiaowen Zhu, Zhi Liang, Zhiming Bao, Jiayuan Zhang, Jieyu Guo, Hui Guo
Zinc (Zn) is an essential trace element for the normal physiological function of aquatic organisms, but it could become toxic to organisms when the concentration increased in water. As the first line of defense, the shrimp intestines are the most susceptible organ to environmental stress. In this study, the chronic toxicity of 0 (control, IC), 0.01(IL), 0.1(IM), and 1 mg/L (IH) Zn in intestines of shrimp Litopenaeus vannamei was investigated from the perspectives of biochemical, histological and transcriptional changes after exposure for 30 days...
March 5, 2024: Chemosphere
https://read.qxmd.com/read/38452673/dinotefuran-exposure-alters-biochemical-metabolomic-gut-microbiome-and-growth-responses-in-decapoda-pacific-white-shrimp-penaeus-vannamei
#26
JOURNAL ARTICLE
Zhenqiang Fu, Zhiyu Lin, Kaiqi Huang, Zhenfei Li, Zhi Luo, Fenglu Han, Erchao Li
Dinotefuran, a neonicotinoid insecticide, may impact nontarget organisms such as Decapoda P. vannamei shrimp with nervous systems similar to insects. Exposing shrimp to low dinotefuran concentrations (6, 60, and 600 μg/L) for 21 days affected growth, hepatosomatic index, and survival. Biomarkers erythromycin-N-demethylase, alanine aminotransferase, and catalase increased in all exposed groups, while glutathione S-transferase is the opposite; aminopyrin-N-demethylase, malondialdehyde, and aspartate aminotransferase increased at 60 and 600 μg/L...
March 2, 2024: Journal of Hazardous Materials
https://read.qxmd.com/read/38450627/lipophilic-group-modified-manganese-ii-based-contrast-agents-for-vascular-and-hepatobiliary-magnetic-resonance-imaging
#27
JOURNAL ARTICLE
Zhongyuan Cai, Lingling Jiang, Yingzi Cao, Shengxiang Fu, Shasha Wang, Yuting Jiang, Haojie Gu, Na Li, Xiaomin Fu, Shimin Tang, Jiang Zhu, Weidong Cao, Lei Zhong, Zhuzhong Cheng, Chunchao Xia, Su Lui, Bin Song, Qiyong Gong, Hua Ai
Effective vascular and hepatic enhancement and better safety are the key drivers for exploring gadolinium-free hepatobiliary contrast agents. Herein, a facile strategy proposes that the high lipophilicity may be favorable to enhancing sequentially vascular and hepatobiliary signal intensity based on the structure-activity relationship that both hepatic uptake and interaction with serum albumins partly depend on lipophilicity. Therefore, 11 newly synthesized derivatives of manganese o -phenylenediamine- N , N , N ', N '-tetraacetic acid (MnLs) were evaluated as vascular and hepatobiliary agents...
March 7, 2024: Journal of Medicinal Chemistry
https://read.qxmd.com/read/38447993/budding-yeast-cap-analysis-of-gene-expression-dataset-of-two-cell-types
#28
JOURNAL ARTICLE
Kei Kawakami, Shin-Ichi Maeda, Yoshiko Tanimoto, Mitsuhiro Shimizu, Hiroaki Kato
The budding yeast Saccharomyces cerevisiae is an excellent model organism for studying chromatin regulation with high-resolution genome-wide analyses. Since newly generated genome-wide data are often compared with publicly available datasets, expanding our dataset repertoire will be beneficial for the field. Information on transcription start sites (TSSs) determined at base pair resolution is essential for elucidating mechanisms of transcription and related chromatin regulation, yet no datasets that cover two different cell types are available...
March 7, 2024: Genes & Genetic Systems
https://read.qxmd.com/read/38447112/recent-advances-in-detection-of-hydroxyl-radical-by-responsive-fluorescence-nanoprobes
#29
JOURNAL ARTICLE
Mazen Alanazi, Jiaxi Yong, Miaomiao Wu, Zexi Zhang, Dihua Tian, Run Zhang
Hydroxyl radical (•OH), a highly reactive oxygen species (ROS), is assumed as one of the most aggressive free radicals. This radical has a detrimental impact on cells as it can react with different biological substrates leading to pathophysiological disorders, including inflammation, mitochondrion dysfunction, and cancer. Quantification of this free radical in-situ plays critical roles in early diagnosis and treatment monitoring of various disorders, like macrophage polarization and tumor cell development...
March 6, 2024: Chemistry, An Asian Journal
https://read.qxmd.com/read/38442212/renewable-electrochemiluminescence-biosensor-based-on-eu-mogs-as-a-highly-efficient-emitter-and-a-dnazyme-mediated-dual-drive-dna-walker-as-a-signal-amplifier-for-ultrasensitive-detection-of-mirna-222
#30
JOURNAL ARTICLE
Yi-Fei Chen, Yu-Zhuo Guo, Shuang Xiao, Ya-Qin Chai, Jia-Li Liu, Ruo Yuan
Herein, novel europium metal-organic gels (Eu-MOGs) with excellent cathode electrochemiluminescence (ECL) emission are first used to construct biosensors for the ultrasensitive detection of miRNA-222. Impressively, N and O elements of organic ligand 2,2':6,2″-terpyridine 4,4',4″-tricarboxylic acid (H3-tctpy) can perfectly coordinate with Eu3+ to form Eu-MOGs, which not only reduce nonradiative transition caused by the intramolecular free rotation of phenyl rings in other MOGs to enhance the ECL signal with extraordinary ECL efficiency as high as 37...
March 5, 2024: Analytical Chemistry
https://read.qxmd.com/read/38441466/comparison-of-tet-x4-containing-contigs-assembled-from-metagenomic-sequencing-data-with-plasmid-sequences-of-isolates-from-a-cohort-of-healthy-subjects
#31
JOURNAL ARTICLE
Yichen Ding, Shuan Er, Abel Tan, Jean-Sebastien Gounot, Woei-Yuh Saw, Linda Wei Lin Tan, Yik Ying Teo, Niranjan Nagarajan, Henning Seedorf
Recently discovered tet (X) gene variants have provided new insights into microbial antibiotic resistance mechanisms and their potential consequences for public health. This study focused on detection, analysis, and characterization of Tet(X4)-positive Enterobacterales from the gut microbiota of a healthy cohort of individuals in Singapore using cultivation-dependent and cultivation-independent approaches. Twelve Tet(X4)-positive Enterobacterales strains that were previously obtained from the cohort were fully genome-sequenced and comparatively analyzed...
March 5, 2024: Microbiology Spectrum
https://read.qxmd.com/read/38438307/the-compatibility-of-cofs-cathode-and-optimized-electrolyte-for-ultra-long-lifetime-rechargeable-aqueous-zinc-ion-battery
#32
JOURNAL ARTICLE
Yifan Wei, Zhonglin Li, Yongyao Liu, Zhenyu Ji, Shuixiang Zou, Yuzhe Zhou, Shuai Yan, Cheng Chen, Mingyan Wu
Rechargeable aqueous zinc-ion batteries (RAZIBs) are attractive due to their affordability, safety, and eco-friendliness. However, their potential is limited by the lack of high-capacity cathodes and compatible electrolytes needed for reliable performance. Herein, we have presented a compatibility strategy for the development of a durable and long-lasting RAZIBs. The covalent organic frameworks (COFs) based on anthraquinone (DAAQ-COF) is created and utilized as the cathode, with zinc metal serving as the anode...
March 4, 2024: ChemSusChem
https://read.qxmd.com/read/38438239/3d-printed-stereolithographic-fluidic-devices-for-automatic-nonsupported-microelectromembrane-extraction-and-clean-up-of-wastewater-samples
#33
JOURNAL ARTICLE
Ali Sahragard, Miloš Dvořák, Carlos Pagan-Galbarro, Enrique Javier Carrasco-Correa, Pavel Kubáň, Manuel Miró
BACKGROUND: There is a quest of novel functional and reliable platforms for enhancing the efficiency of microextraction approaches in troublesome matrices, such as industrial wastewaters. 3D printing has been proven superb in the analytical field to act as the springboard of microscale extraction approaches. RESULTS: In this work, low-force stereolithography (SL) was exploited for 3D printing and prototyping bespoke fluidic devices for accommodating nonsupported microelectromembrane extraction (μEME)...
April 8, 2024: Analytica Chimica Acta
https://read.qxmd.com/read/38437020/technical-tips-the-role-of-the-charge-neurodiagnostic-technologist
#34
JOURNAL ARTICLE
Erik Padilla, Sindy Navarro, Karen Richey, Mariana Vicenteno
The purpose of this strategic staffing study was to retrospectively evaluate the impact of the charge neurodiagnostic technologist (NDT) within a 24/7 pediatric NAEC Level IV, ABRET LAB-LTM accredited epilepsy monitoring unit (EMU) during a 4-month pilot. The association between a high-reliability organization (HRO), Lean thinking, and organizational strategic goals were utilized as guiding principles. This paper reviews the operational need to further develop frontline neurodiagnostic leadership roles within Ann & Robert H...
March 4, 2024: Neurodiagnostic Journal
https://read.qxmd.com/read/38432551/development-of-a-multiplex-droplet-digital-pcr-assay-for-simultaneous-detection-and-quantification-of-escherichia-coli-e-marmotae-and-e-ruysiae-in-water-samples
#35
JOURNAL ARTICLE
Marie Moinet, Rose M Collis, Lynn Rogers, Megan L Devane, Patrick J Biggs, Rebecca Stott, Jonathan Marshall, Richard Muirhead, Adrian L Cookson
Escherichia coli are widely used by water quality managers as Fecal Indicator Bacteria, but current quantification methods do not differentiate them from benign, environmental Escherichia species such as E. marmotae (formerly named cryptic clade V) or E. ruysiae (cryptic clades III and IV). Reliable and specific techniques for their identification are required to avoid confounding microbial water quality assessments. To address this, a multiplex droplet digital PCR (ddPCR) assay targeting lipB (E. coli and E...
March 1, 2024: Journal of Microbiological Methods
https://read.qxmd.com/read/38430772/green-synthesis-of-azo-linked-porous-organic-polymer-for-enrichment-of-nitroimidazoles-from-water-shrimp-and-basa-fish
#36
JOURNAL ARTICLE
Yiran Dou, Cong Liu, Xiaocui Chen, Xiumin Yang, Lin Hao, Qianqian Wang, Zhi Wang, Qiuhua Wu, Chun Wang
Reliable monitoring of nitroimidazoles (NDZs) is of great significance to public health. Herein, an azo-linked porous organic polymer (Res-POPs) was prepared by green synthesis method using natural resveratrol as monomer for the first time. Using Res-POPs as sorbent, a facile method coupling solid-phase extraction with high performance liquid chromatography-diode array detection was developed for effective detecting NDZs. The method achieved good linearities (0.06 ∼ 100 ng mL-1 for water, 1...
February 28, 2024: Food Chemistry
https://read.qxmd.com/read/38430283/microstate-analysis-of-continuous-infant-eeg-tutorial-and-reliability
#37
JOURNAL ARTICLE
Armen Bagdasarov, Denis Brunet, Christoph M Michel, Michael S Gaffrey
Microstate analysis of resting-state EEG is a unique data-driven method for identifying patterns of scalp potential topographies, or microstates, that reflect stable but transient periods of synchronized neural activity evolving dynamically over time. During infancy - a critical period of rapid brain development and plasticity - microstate analysis offers a unique opportunity for characterizing the spatial and temporal dynamics of brain activity. However, whether measurements derived from this approach (e.g...
March 2, 2024: Brain Topography
https://read.qxmd.com/read/38426764/carbapenem-resistant-acinetobacter-baumannii-carrier-detection-a-simple-and-efficient-protocol
#38
JOURNAL ARTICLE
Jonathan Lellouche, Alona Keren-Paz, Reut Rov, Reut Efrati Epchtien, Sammy Frenk, Amichay Hameir, Elizabeth Temkin, David Schwartz, Yehuda Carmeli
UNLABELLED: Timely detection of carbapenem-resistant Acinetobacter baumannii (CRAB) carriers is essential to direct infection control measures. In this work, we aimed to develop a practical protocol to detect CRAB from screening samples. To choose a selective medium that detects CRAB with high sensitivity and specificity, 111 A . baumannii clinical isolates were inoculated on three types of agar: mSuperCARBA (SC), CHROMagar Acinetobacter (CaA), and modified CHROMagar Acinetobacter (mCaA) containing 4...
March 1, 2024: Microbiology Spectrum
https://read.qxmd.com/read/38426382/nurse-led-renal-cell-carcinoma-clinic-a-single-center-review
#39
JOURNAL ARTICLE
I Thia, A Tan, E Botha, A Picardo, M Brown, I Thyer, A Abdul-Hamid, A Tan, D Teichmann, D Hayne, S P McCombie
BACKGROUND: In 2015 our centre introduced a nurse-led renal cell cancer follow-up protocol and clinic for patients who have undergone partial or radical nephrectomy for organ-confined kidney tumours. The main aims of this clinic were to improve healthcare efficiency and standardize follow-up processes. OBJECTIVES: The primary objective was to assess the effectiveness of a nurse-led renal cell cancer follow up clinic in regard to surveillance protocol compliance and the timely identification and appropriate management of recurrences...
March 1, 2024: ANZ Journal of Surgery
https://read.qxmd.com/read/38425488/can-researchers-trust-icd-10-coding-of-medical-comorbidities-in-orthopaedic-trauma-patients
#40
JOURNAL ARTICLE
Rodney Arthur, R Miles Mayberry, Susan Odum, Laurence B Kempton
OBJECTIVES: The 10th revision of the International Classification of Diseases (ICD-10) coding system may prove useful to orthopaedic trauma researchers to identify and document populations based on comorbidities. However, its use for research first necessitates determination of its reliability. The purpose of this study was to assess the reliability of electronic medical record (EMR) ICD-10 coding of nonorthopaedic diagnoses in orthopaedic trauma patients relative to the gold standard of prospective data collection...
March 2024: OTA international: the open access journal of orthopaedic trauma
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