keyword
MENU ▼
Read by QxMD icon Read
search

High reliability organization

keyword
https://www.readbyqxmd.com/read/29457382/an-international-multi-specialty-validation-study-of-the-igg4-related-disease-responder-index
#1
Zachary S Wallace, Arezou Khosroshahi, Mollie D Carruthers, Cory A Perugino, Hyon Choi, Corrado Campochiaro, Emma L Culver, Frank Cortazar, Emanuel Dellatorre, Mikael Ebbo, Ana Fernandes, Luca Frulloni, Philip Hart, Omer Karadag, Shigeyuki Kawa, Mitsuhiro Kawano, Myung-Hwan Kim, Marco Lanzillotta, Shoko Matsui, Kazuichi Okazaki, Jay H Ryu, Takako Saeki, Nicolas Schleinitz, Paula Tanasa, Hisanori Umehara, George Webster, Wen Zhang, John H Stone
OBJECTIVE: IgG4-related disease (IgG4-RD) can cause fibro-inflammatory lesions in nearly any organ, leading to organ dysfunction and failure. The IgG4-RD Responder Index (RI) was developed to help investigators assess the efficacy of treatment in a structured manner. We sought to validate the RI in a multi-national investigation. METHODS: The RI guides investigators through assessments of disease activity and damage in 25 domains, incorporating higher weights for disease manifestations that require treatment urgently or that worsen despite treatment...
February 18, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29457367/sperm-morphological-normality-under-high-magnification-is-correlated-to-male-infertility-and-predicts-embryo-development
#2
B F Zanetti, D P A F Braga, R R Provenza, R C S Figueira, A Iaconelli, E Borges
Human sperm morphology has been described as an essential parameter for the diagnosis of male infertility and a prognostic indicator of natural or assisted pregnancies. Nevertheless, standard morphological assessment remains a subjective analysis and its impact on intracytoplasmic sperm injection (ICSI) is also of limited value. The objective of this prospective cohort study was to investigate whether motile sperm organelle morphology examination (MSOME) can improve semen analysis by better defining male infertility and providing a better prognosis for ICSI up to a year later...
February 18, 2018: Andrology
https://www.readbyqxmd.com/read/29455140/comparison-of-soil-organic-carbon-speciation-using-c-nexafs-and-cpmas-13-c-nmr-spectroscopy
#3
Jörg Prietzel, Svenja Müller, Ingrid Kögel-Knabner, Jürgen Thieme, Cherno Jaye, Daniel Fischer
We compared synchrotron-based C near-edge X-ray absorption fine structure (NEXAFS) and CPMAS13 C nuclear magnetic resonance (NMR) spectroscopy with respect to their precision and accuracy to quantify different organic carbon (OC) species in defined mixtures of soil organic matter source compounds. We also used both methods to quantify different OC species in organic surface horizons of a Histic Leptosol as well as in mineral topsoil and subsoil horizons of two soils with different parent material, stage of pedogenesis, and OC content (Cambisol: 15-30 OC mgg-1 , Podzol: 0...
February 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29454935/dynamic-resting-state-fmri-analysis-in-mice-reveals-a-set-of-quasi-periodic-patterns-and-illustrates-their-relationship-with-the-global-signal
#4
REVIEW
Michaël E Belloy, Maarten Naeyaert, Anzar Abbas, Disha Shah, Verdi Vanreusel, Johan van Audekerke, Shella D Keilholz, Georgios A Keliris, Annemie Van der Linden, Marleen Verhoye
Time-resolved 'dynamic' over whole-period 'static' analysis of low frequency (LF) blood-oxygen level dependent (BOLD) fluctuations provides many additional insights into the macroscale organization and dynamics of neural activity. Although there has been considerable advancement in the development of mouse resting state fMRI (rsfMRI), very little remains known about its dynamic repertoire. Here, we report for the first time the detection of a set of recurring spatiotemporal Quasi-Periodic Patterns (QPPs) in mice, which show spatial similarity with known resting state networks...
February 15, 2018: NeuroImage
https://www.readbyqxmd.com/read/29454360/reliability-of-length-measurements-collected-by-community-nurses-and-health-volunteers-in-rural-growth-monitoring-and-promotion-services
#5
Matilda E Laar, Grace S Marquis, Anna Lartey, Katherine Gray-Donald
BACKGROUND: Length measurements are important in growth, monitoring and promotion (GMP) for the surveillance of a child's weight-for-length and length-for-age. These two indices provide an indication of a child's risk of becoming wasted or stunted, and are more informative about a child's growth than the widely used weight-for-age index (underweight). Although the introduction of length measurements in GMP is recommended by the World Health Organization, concerns about the reliability of length measurements collected in rural outreach settings have been expressed by stakeholders...
February 17, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29453681/-18-f-fpybf-2-a-new-f-18-labelled-amyloid-imaging-pet-tracer-biodistribution-and-radiation-dosimetry-assessment-of-first-in-man-18-f-fpybf-2-pet-imaging
#6
Ryuichi Nishii, Tatsuya Higashi, Shinya Kagawa, Chio Okuyama, Yoshihiko Kishibe, Masaaki Takahashi, Tomoko Okina, Norio Suzuki, Hiroshi Hasegawa, Yasuhiro Nagahama, Koichi Ishizu, Naoya Oishi, Hiroyuki Kimura, Hiroyuki Watanabe, Masahiro Ono, Hideo Saji, Hiroshi Yamauchi
OBJECTIVE: Recently, a benzofuran derivative for the imaging of β-amyloid plaques, 5-(5-(2-(2-(2- 18 F-fluoroethoxy)ethoxy)ethoxy)benzofuran-2-yl)- N-methylpyridin-2-amine ( 18 F-FPYBF-2) has been validated as a tracer for amyloid imaging and it was found that 18 F-FPYBF-2 PET/CT is a useful and reliable diagnostic tool for the evaluation of AD (Higashi et al. Ann Nucl Med, https://doi.org/10.1007/s12149-018-1236-1 , 2018). The aim of this study was to assess the biodistribution and radiation dosimetry of diagnostic dosages of 18 F-FPYBF-2 in normal healthy volunteers as a first-in-man study...
February 16, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29453067/applying-no-depletion-equilibrium-sampling-and-full-depletion-bioaccessibility-extraction-to-35-historically-polycyclic-aromatic-hydrocarbon-contaminated-soils
#7
Nora Bartolomé, Isabel Hilber, Dayana Sosa, Rainer Schulin, Philipp Mayer, Thomas D Bucheli
Assessing the bioaccessibility of organic pollutants in contaminated soils is considered a complement to measurements of total concentrations in risk assessment and legislation. Consequently, methods for its quantification require validation with historically contaminated soils. In this study, 35 such soils were obtained from various locations in Switzerland and Cuba. They were exposed to different pollution sources (e.g., pyrogenic and petrogenic) at various distance (i.e., urban to rural) and were subject to different land use (e...
February 3, 2018: Chemosphere
https://www.readbyqxmd.com/read/29453022/exploring-factors-that-influence-students-attitudes-toward-midwifery-in-jordan-measuring-psychometric-properties-of-a-newly-developed-tool
#8
Lourance A Al Hadid, Omaymah Al-Rajabi, Marwa AlBarmawi, Najah Sayyah Yousef Sayyah, Lwiza Moh'd Toqan
Students' professional choice to proceed in midwifery is influenced by many factors. This study validated an instrument developed to assess students' attitudes toward midwifery in Jordan. It also addressed the motivating and de-motivating factors influencing students' decision concerning joining and continuing in midwifery. A descriptive, cross-section study was conducted on a convenience sample of 374 midwifery students representing private, governmental, and military midwifery colleges. The researchers developed the study questionnaire through conducting a comprehensive literature review, organizing common themes and consulting experts...
February 8, 2018: Nurse Education in Practice
https://www.readbyqxmd.com/read/29448125/a-critical-review-of-histopathological-findings-associated-with-endocrine-and-non-endocrine-hepatic-toxicity-in-fish-models
#9
REVIEW
Jeffrey C Wolf, James R Wheeler
Although frequently examined as a target organ for non-endocrine toxicity, histopathological evaluation of the liver is becoming a routine component of endocrine disruption studies that utilize various fish species as test subjects. However, the interpretation of microscopic liver findings can be challenging, especially when attempting to distinguish adverse changes associated with endocrine disrupting substances from those caused by systemic or direct hepatic toxicity. The purpose of this project was to conduct a critical assessment of the available peer-reviewed and grey literature concerning the histopathologic effects of reproductive endocrine active substances (EAS) and non-endocrine acting substances in the livers of fish models, and to determine if liver histopathology can be used to reliably distinguish endocrine from non-endocrine etiologies...
February 12, 2018: Aquatic Toxicology
https://www.readbyqxmd.com/read/29443733/serial-evaluation-of-the-sofa-score-is-reliable-for-predicting-mortality-in-acute-severe-pancreatitis
#10
Yu-San Tee, Hsin-Yueh Fang, I-Ming Kuo, Yann-Sheng Lin, Song-Fong Huang, Ming-Chin Yu
Acute severe pancreatitis caused high mortality, and several scoring systems for predicting mortality are available. We evaluated the effectiveness of serial measurement of several scoring systems in patients with acute severe pancreatitis.We retrospectively obtained serial measurements of Ranson, Acute Physiology and Chronic Health Assessment (APACHE) II, and Sequential Organ Failure Assessment (SOFA) scores of 159 patients with acute severe pancreatitis.The overall mortality rate was 20%, and early mortality (in the first 2 weeks) occurred in 10 (7...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29441133/polarization-spectroscopy-methods-in-the-determination-of-interactions-of-small-molecules-with-nucleic-acids-tutorial
#11
REVIEW
Tamara Šmidlehner, Ivo Piantanida, Gennaro Pescitelli
The structural characterization of non-covalent complexes between nucleic acids and small molecules (ligands) is of a paramount significance to bioorganic research. Highly informative methods about nucleic acid/ligand complexes such as single crystal X-ray diffraction or NMR spectroscopy cannot be performed under biologically compatible conditions and are extensively time consuming. Therefore, in search for faster methods which can be applied to conditions that are at least similar to the naturally occurring ones, a set of polarization spectroscopy methods has shown highly promising results...
2018: Beilstein Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29439658/high-fidelity-hypothermic-preservation-of-primary-tissues-in-organ-transplant-preservative-for-single-cell-transcriptome-analysis
#12
Wanxin Wang, Lolita Penland, Ozgun Gokce, Derek Croote, Stephen R Quake
BACKGROUND: High-fidelity preservation strategies for primary tissues are in great demand in the single cell RNAseq community. A reliable method would greatly expand the scope of feasible multi-site collaborations and maximize the utilization of technical expertise. When choosing a method, standardizability and fidelity are important factors to consider due to the susceptibility of single-cell RNAseq analysis to technical noise. Existing approaches such as cryopreservation and chemical fixation are less than ideal for failing to satisfy either or both of these standards...
February 13, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29436122/the-zebrafish-a-fintastic-model-for-hematopoietic-development-and-disease
#13
REVIEW
Aniket V Gore, Laura M Pillay, Marina Venero Galanternik, Brant M Weinstein
Hematopoiesis is a complex process with a variety of different signaling pathways influencing every step of blood cell formation from the earliest precursors to final differentiated blood cell types. Formation of blood cells is crucial for survival. Blood cells carry oxygen, promote organ development and protect organs in different pathological conditions. Hematopoietic stem and progenitor cells (HSPCs) are responsible for generating all adult differentiated blood cells. Defects in HSPCs or their downstream lineages can lead to anemia and other hematological disorders including leukemia...
February 13, 2018: Wiley Interdisciplinary Reviews. Developmental Biology
https://www.readbyqxmd.com/read/29433723/reviewing-lung-cancer-screening-the-who-where-when-why-and-how
#14
REVIEW
Brett C Bade, Paul B Brasher, Branden W Luna, Gerard A Silvestri, Nichole T Tanner
Lung cancer screening with annual low-dose computed tomography (CT) decreases lung cancer mortality in high-risk patients, as defined by smoking history (> 30 pack-years) and age (55-74 years). Risks to screening include overdiagnosis, anxiety about indeterminate nodules, and radiation exposure. To be effective, lung cancer screening must combine individualized risk assessment, shared decision-making, smoking cessation, structured reporting, high quality and multi-specialty cancer care, and reliable follow-up; a multidisciplinary approach is crucial...
March 2018: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/29433487/development-and-validation-of-a-questionnaire-to-evaluate-the-factors-influencing-training-transfer-among-nursing-professionals
#15
Yangjing Bai, Jiping Li, Yangjuan Bai, Weiguang Ma, Xiangyu Yang, Fang Ma
BACKGROUND: Most organizations invest in people for training to improve human capital and maximize profitability. Yet it is reported in industry and nursing as well that training effectiveness is constrained because of inadequate transfer of training and the underlying reasons for the transfer problem remain unknown. And there is lack of tool to measure transfer problem. METHODS: The purpose of this study was to develop and validate a questionnaire to evaluate the scores of factors influencing training transfer (FITT) among nursing professionals...
February 13, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29430662/on-the-feasibility-of-automatically-selecting-similar-patients-in-highly-individualized-radiotherapy-dose-reconstruction-for-historic-data-of-pediatric-cancer-survivors
#16
Marco Virgolin, Irma W E M van Dij, Jan Wiersma, Cécile M Ronckers, Cees Witteveen, Arjan Bel, Tanja Alderliesten, Peter A N Bosman
PURPOSE: The aim of this study is to establish the first step towards a novel and highly individualized 3D dose distribution reconstruction method, based on CT scans and organ delineations of recently treated patients. Specifically, the feasibility of automatically selecting the CT scan of a recently treated childhood cancer patient who is similar to a given historically treated child who suffered from Wilms' tumor is assessed. METHODS: A cohort of 37 recently treated children between 2 and 6 years old is considered...
February 12, 2018: Medical Physics
https://www.readbyqxmd.com/read/29427897/spatial-aggregation-of-holistically-nested-convolutional-neural-networks-for-automated-pancreas-localization-and-segmentation
#17
Holger R Roth, Le Lu, Nathan Lay, Adam P Harrison, Amal Farag, Andrew Sohn, Ronald M Summers
Accurate and automatic organ segmentation from 3D radiological scans is an important yet challenging problem for medical image analysis. Specifically, as a small, soft, and flexible abdominal organ, the pancreas demonstrates very high inter-patient anatomical variability in both its shape and volume. This inhibits traditional automated segmentation methods from achieving high accuracies, especially compared to the performance obtained for other organs, such as the liver, heart or kidneys. To fill this gap, we present an automated system from 3D computed tomography (CT) volumes that is based on a two-stage cascaded approach-pancreas localization and pancreas segmentation...
February 1, 2018: Medical Image Analysis
https://www.readbyqxmd.com/read/29426521/superhydrophobic-titania-nanoparticles-for-fabrication-of-paper-based-analytical-devices-an-example-of-heavy-metals-assays
#18
Wenjian Xu, Xi Chen, Songcai Cai, Jin Chen, Zhen Xu, Hongpeng Jia, Jing Chen
A new strategy has been introduced to successfully fabricate the hydrophobic barriers of PADs by using organofluorine-modified superhydrophobic TiO2 NPs. Superhydrophobic TiO2-140 NPs with high-photoactivity can be converted to hydrophilicity by self-degradation of surface organic moieties under full spectrum light irradiation. Superhydrophobic TiO2-RT NPs with low-photoactivity exhibits good hydrophobic stability under light irradiation. Thus, combining these features, the PADs have been designed and constructed by photo-induced fabrication of hydrophobic barriers on the surface of the paper...
May 1, 2018: Talanta
https://www.readbyqxmd.com/read/29426177/large-variation-in-glyphosate-mineralization-in-21-different-agricultural-soils-explained-by-soil-properties
#19
Nghia Khoi Nguyen, Ulrike Dörfler, Gerhard Welzl, Jean Charles Munch, Reiner Schroll, Marjetka Suhadolc
Glyphosate and its main metabolite aminomethylphosphonic acid (AMPA) have frequently been detected in surface water and groundwaters. Since adequate glyphosate mineralization in soil may reduce its losses to environment, improved understanding of site specific factors underlying pesticide mineralization in soils is needed. The aim of this study was to investigate the relationship between soil properties and glyphosate mineralization. To establish a sound basis for resilient correlations, the study was conducted with a large number of 21 agricultural soils, differing in a variety of soil parameters, such as soil texture, soil organic matter content, pH, exchangeable ions etc...
January 30, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29425405/tunable-crystallinity-and-charge-transfer-in-2-dimensional-g-quadruplex-organic-frameworks
#20
Michael R Wasielewski, Yi-Lin Wu, N Scott Bobbitt, Jenna Logsdon, Natalia Powers-Riggs, Jordan Nelson, Xiolong Liu, Timothy Wang, Randall Snurr, Joseph Hupp, Omar Farha, Mark Hersam
DNA G-quadruplex structures were recently discovered to provide reliable scaffolding for two-dimensional organic frameworks due to the strong hydrogen-bonding ability of guanine. In this work, 2,7-diaryl pyrene building blocks with high HOMO energies and large optical gaps are incorporated into G-quadruplex organic frameworks. The adjustable substitution on the aryl groups provides an opportunity to elucidate the framework formation mechanism; molecular non-planarity is found to be beneficial for restricting interlayer slippage, and the framework crystallinity is highest when intermolecular interaction and non-planarity strike a fine balance...
February 9, 2018: Angewandte Chemie
keyword
keyword
63000
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"