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Piotr Kocełak, Aleksander Owczarek, Maria Bożentowicz-Wikarek, Aniceta Brzozowska, Małgorzata Mossakowska, Tomasz Grodzicki, Andrzej Więcek, Jerzy Chudek, Magdalena Olszanecka-Glinianowicz
PURPOSE: The aim of the study was to assess plasma RBP4 concentration in elderly subjects in relation to nutritional status and kidney function in the population of the PolSenior Study. MATERIAL AND METHODS: We assessed RBP4, glucose, insulin, albumin, lipid profile, C-reactive protein, (hsCRP) and creatinine concentrations in 2614 PolSenior Study participants (1235 women and 1379 men). The study group was divided based on BMI and HOMA-IR values, and the occurrence of diabetes...
July 16, 2018: Advances in Medical Sciences
Susann Regber, Jovanna Dahlgren, Staffan Janson
OBJECTIVE: To explore key person's perspectives of foster home placement or notification of risk of harm to Social Services of children with severe obesity. METHODS: This case study research was performed in the southwest of Sweden and based on interviews with nine informants: a foster home youth, two foster parents, a social worker, two hospital social workers, a pediatric physician, a pediatric nurse, and a psychologist. Content analysis was used for narrative evaluations, within- and cross case analyses and displays...
July 16, 2018: Child Abuse & Neglect
Marco Spangaro, Elena Mazza, Sara Poletti, Roberto Cavallaro, Francesco Benedetti
BACKGROUND: White matter (WM) alterations have been consistently described in patients with schizophrenia and correlated with the severity of psychotic symptoms and cognitive impairment. Obesity has been reported in over 40% of patients with schizophrenia and has been associated with cognitive deficits, cardiovascular diseases, metabolic alterations, and overall mortality. Moreover, studies among healthy subjects and subjects at risk for psychosis reported an influence of Body Mass Index (BMI) on structural connectivity...
July 16, 2018: Psychoneuroendocrinology
Liguo Zhu, Jie Jiang, Xiangjun Zhai, Aileen Baecker, Hong Peng, Jiao Qian, MingHao Zhou, Ci Song, Yan Zhou, Jianfang Xu, Hongjian Liu, Dong Hang, Zhibin Hu, Hongbin Shen, Zuo-Feng Zhang, Fengcai Zhu
BACKGROUND & AIMS: Although non-alcoholic fatty liver disease (NAFLD) has been studied extensively, the potential risk factors for NAFLD among chronic hepatitis B (CHB) patients have not been fully known. METHODS: A population-based cohort of adult CHB patients without a history of alcohol drinking or NAFLD were recruited and followed up from October 2012 to January 2015 in Jiangsu province, China. Using Cox proportional hazards regression model, potential risk factors including viral and metabolic factors for NAFLD were evaluated...
July 19, 2018: Liver International: Official Journal of the International Association for the Study of the Liver
Tom Jg Gevers, B W Marcel Spanier, Peter B Veendrick, Jan Maarten Vrolijk
BACKGROUND & AIM: Obesity and metabolic syndrome are increasingly recognized as risk factors for hepatocellular adenomas (HCA). There is still sparse evidence whether weight loss or bariatric surgery could induce HCA regression in these patients. In this brief report we describe the effect of weight loss on HCA regression in severe obese patients that had undergone bariatric surgery in our center. METHODS: We performed an Electronic Patient Database search and included all patients who underwent bariatric surgery in our bariatric referral center and had an ICD-10 code of benign neoplasm of liver in our center from (2006-2017)...
July 19, 2018: Liver International: Official Journal of the International Association for the Study of the Liver
Shiao Wei Quah, Hazreen Abdul Majid, Nabilla Al-Sadat, Abqariyah Yahya, Tin Tin Su, Muhammad Yazid Jalaludin
BACKGROUND: This study is to determine the prevalence and risk factors of vitamin D deficiency (vitamin D ≤ 50 nmol/L) among 15-year-old Malaysian adolescents. By identifying potential risk factors, prevention strategies and interventions can be carried out to improve the vitamin D status in adolescents. METHODS AND FINDINGS: Stratified random sampling design was used to select adolescents from 15 urban and rural secondary schools in Selangor, Perak and Kuala Lumpur, Malaysia...
2018: PloS One
Bruna Kulik Hassan, Diana Barbosa Cunha, Gloria Valeria da Veiga, Rosangela Alves Pereira, Rosely Sichieri
OBJECTIVES: To estimate changes over time of breakfast frequency and foods/food groups consumed at breakfast. METHODS: Cohort of 809 students aged 10-16 years old from Rio de Janeiro, Brazil, enrolled in 2010, and followed for three years. Breakfast skippers were those not eating breakfast. Those with breakfast frequency of 4 or less times per week were considered irregular breakfast eaters. Changes over time of breakfast frequency and breakfast foods/food groups were analyzed by generalized estimating equations...
2018: PloS One
Ai Ibuki, Takeo Minematsu, Mikako Yoshida, Shinji Iizaka, Masaru Matsumoto, Junko Sugama, Hiromi Sanada
We previously reported elevated oxidative stress-related mechanical vulnerabilities of the skin as sparse distributions of hyperechoic areas. Although this helped establish a personalized skin care system to prevent skin disorders related to mechanical stress, obesity-related skin vulnerability involves individual differences. Here, we hypothesized that individual differences are caused by polymorphisms of GT repetitive sequences in the heme oxygenase1 (HMOX1) promoter region, which encodes an antioxidant enzyme...
2018: PloS One
Candace C Nelson, Rachel Colchamiro, Meghan Perkins, Elsie M Taveras, Peggy Leung-Strle, JoAnn Kwass, Jennifer A Woo Baidal
OBJECTIVES: To investigate racial/ethnic and language differences in the effectiveness of the Massachusetts Childhood Obesity Research Demonstration (MA-CORD) study among children aged 2 to 4 years enrolled in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC). METHODS: We performed a multisector quasiexperimental study in 2 MA-CORD intervention communities and 1 comparison community. Using WIC data from 2010 to 2015, we examined intervention effect on child weight and behavior outcomes by child race/ethnicity and parental primary language using multilevel linear regression models with an interaction term...
July 19, 2018: American Journal of Public Health
Julia L Marcus, Kenneth Levine, Chris Grasso, Douglas S Krakower, Victoria Powell, Kyle T Bernstein, Stephen Boswell, Kenneth H Mayer
OBJECTIVES: To determine whether HIV preexposure prophylaxis (PrEP) use is associated with use of non-HIV-related health care. METHODS: We conducted a cross-sectional study of potential PrEP candidates at a Boston, Massachusetts, community health clinic during 2012 to 2016, comparing the proportion of PrEP users and non-PrEP users receiving primary care. RESULTS: Of 5857 PrEP candidates, 2047 (35%) were prescribed PrEP. After adjustment for demographics and number of visits, more PrEP users received influenza vaccination (prevalence ratio [PR] = 1...
July 19, 2018: American Journal of Public Health
Mustafa Bseikri, Joyce C McCann, Ashutosh Lal, Edward Fong, Kirsten Graves, Alisa Goldrich, Devan Block, Ginny L Gildengoren, Michele Mietus-Snyder, Mark Shigenaga, Jung Suh, Karen Hardy, Bruce N Ames
Asthma in the obese is often severe, difficult to treat, and characterized by less eosinophilic inflammation than asthma in the nonobese. Obesity-associated metabolic dysregulation may be a causal factor. We previously reported that a nutrient- and fiber-dense bar [Children's Hospital Oakland Research Institute (CHORI)-bar], which was designed to fill gaps in poor diets, improved metabolism in healthy overweight/obese (OW/OB) adults. In this pilot trial, OW/OB adolescents with poorly controlled asthma were randomized to weekly nutrition/exercise classes with or without twice-daily CHORI-bar consumption...
July 19, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
Isabelle Cote, Hale Z Toklu, Sara M Green, Drake Morgan, Christy S Carter, Nihal Tumer, Philip J Scarpace
Reducing body weight has been shown to lower blood pressure in obesity-related hypertension. However, success of those lifestyle interventions is limited due to poor long-term compliance. Emerging evidence indicate that feeding schedule plays a role on the regulation of blood pressure. With two studies, we examined the role of feeding schedule on energy homeostasis and blood pressure. In Study 1, rats were fed a high fat diet (HFD) ad libitum for 24 hours (Control) or for 12 hours during the dark phase (time-restricted feeding; TRF)...
July 19, 2018: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
N Guerra Diaz, C Sempoux, A Jouret-Mourin, C de Burbure, P Druez
A 64 year-old Caucasian man was first investigated 21 years ago for persistent diarrhoea. A colonoscopy revealed an erosive pancolitis with unusual vacuolated macrophages. Characteristics of ulcerative colitis or Crohn's disease were absent. Similar findings were observed consistently over the following years. A treatment with Sulfasalazine, Methotrexate or Budesonide was efficient. Histiocytic colitis is rare, and the various causes and different diagnoses are reviewed. The cause for the chronic pancolitis in this obese chronic alcoholic remains unknown at the time of writing...
April 2018: Acta Gastro-enterologica Belgica
A A Ersahin, E Çalışkan
OBJECTIVE: To determine whether clomiphene citrate (CC) treatment affects the metabolite contents of a dominant follicle in polycystic ovary syndrome (PCOS). PATIENTS AND METHODS: Twenty non-obese primary infertile anovulatory PCOS women undergoing CC treatment and ten fertile women were enrolled. 6 out of 20 patients had impaired glucose tolerance test (IGT). CC was given at a dose of 150 mg on days 3-7 of cycles in the first group. 10 fertile women with a regular menstrual cycle and normal ovaries during ultrasound examination were accepted as control group...
July 2018: European Review for Medical and Pharmacological Sciences
Jing Su, Yan Li, Guanglong Su, Jing Wang, Ting Qiu, Rong Ma, Lei Zhao
The autoimmune and gene etiology are implicated in the pathogenesis of polycystic ovary syndrome (PCOS). The cytotoxic T-lymphocyte-associated antigen 4 (CTLA4) is important for negative regulation of T-cell activation, and CTLA4 gene has been identified as a risk factor for some autoimmune diseases. However, none studies have been performed about the association between PCOS and the CTLA4 gene before. Here, we aimed to investigate the association of CTLA4 with PCOS in the Chinese Han population though a case-control association analysis of 606 individuals...
July 2018: Medicine (Baltimore)
Anna Vittoria Mattioli, Antonio Manenti, Alberto Farinetti
No abstract text is available yet for this article.
July 17, 2018: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
Kathleen Bornhoeft
Background and Problem Statement: Obesity is a prevalent chronic disease associated with decreased life expectancy, increased morbidity and mortality, and escalating health care costs. PURPOSE: To explore perceptions, attitudes, and behaviors toward obesity management by providers in primary care. METHOD: Data were collected through a descriptive qualitative design using semi-structured face-to-face interviews at primary care practices. RESULTS: Common barriers to obesity management were identified and three major themes emerged; provider centered obstacles, perceived organizational obstacles, and provider perception of patient obstacles...
July 2018: Journal of Community Health Nursing
Melessa N Kelley, John R Lowe
This community-based study explored the effectiveness of an after-school cultural-based intervention for Native American youth at risk for obesity. A standard health education after-school program served as the comparison control condition. Cherokee self-reliance (cultural identity), perceived stress, and obesity knowledge and related behaviors were the three outcome measures evaluated at baseline and immediate post-intervention. Findings revealed that participants who completed the cultural-based intervention had better results on the three outcome measures in comparison to the standard health education program...
July 2018: Journal of Community Health Nursing
Kara P Wiseman, Minal Patel, Laura A Dwyer, Linda C Nebeling
OBJECTIVE: Family-based physical activity interventions have the potential to reduce obesity, but more information is needed regarding physical activity in the family context. This study used an actor-partner interdependence model to estimate the dyadic association between perceived weight status and barriers to physical activity in dyads of adults and their adolescent children. It was hypothesized that greater perceived weight would be associated with greater barriers perceived by both one's self and one's partner...
August 2018: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
Peter Elsborg, Anne-Marie Elbe
OBJECTIVE: The present study investigated the influence of exercise-specific motivation and volition on weight loss maintenance following an intensive lifestyle intervention (ILI). METHOD: The study participants were 164 individuals with obesity (body mass index [BMI] > 30 kg/m2) that participated in an ILI. Participants' exercise-specific volition and motivation were assessed before and after the intervention as well as 3 and 12 months after completion. Volition was measured with the Volition in Exercise Questionnaire and motivation was measured with the context translated Sport Motivation Scale...
August 2018: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
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