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Magnesium pain

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https://www.readbyqxmd.com/read/28797894/neuraxial-magnesium-sulfate-improves-postoperative-analgesia-in-cesarean-section-delivery-women-a-meta-analysis-of-randomized-controlled-trials
#1
Shih-Ching Wang, Po-Ting Pan, Hsiao-Yean Chiu, Chun-Jen Huang
BACKGROUND: We conducted this meta-analysis to elucidate whether additional neuraxial magnesium sulfate (MgSO4) can improve postoperative analgesia in women undergoing Cesarean section (CS) delivery. METHOD: We searched Pubmed, Embase and ClinicalTrial.gov. We included only randomized controlled trials that have compared the quality of postoperative analgesia with and without additional neuraxial MgSO4 in women undergoing CS delivery with neuraxial anesthesia regimens...
July 29, 2017: Asian J Anesthesiol
https://www.readbyqxmd.com/read/28757921/the-impact-of-magnesium-sulfate-as-adjuvant-to-intrathecal-bupivacaine-on-intra-operative-surgeon-satisfaction-and-postoperative-analgesia-during-laparoscopic-gynecological-surgery-randomized-clinical-study
#2
Khaled Salah Mohamed, Sayed Kaoud Abd-Elshafy, Ali Mahmoud El Saman
BACKGROUND: Surgeon satisfaction and patient analgesia during the procedure of laparoscopic surgery are important issues. The aim of this work was to study if an intrathecal (IT) Bupivacaine combined with Magnesium sulfate may or may not provide good surgeon satisfaction in addition to improvement of intraoperative and postoperative analgesia. METHODS: Sixty female patients were enrolled in this prospective, randomized, double-blind controlled clinical trial study...
July 2017: Korean Journal of Pain
https://www.readbyqxmd.com/read/28757917/intravenous-caffeine-citrate-vs-magnesium-sulfate-for-reducing-pain-in-patients-with-acute-migraine-headache-a-prospective-quasi-experimental-study
#3
Alireza Baratloo, Sahar Mirbaha, Hossein Delavar Kasmaei, Pooya Payandemehr, Ahmed Elmaraezy, Ahmed Negida
BACKGROUND: Current evidence suggests that intravenous magnesium sulfate might be effective for reducing migraine pain. In a recent pilot study, we showed that intravenous caffeine citrate could reduce the severity of migraine headache. The objective of this study is to investigate the efficacy of intravenous caffeine citrate vs. magnesium sulfate for management of acute migraine headache. METHODS: We conducted a prospective quasi-experimental study from January until May 2016 in two educational medical centers of Shahid Beheshti University of Medical Sciences (Shoahadaye Tajrish Hospital and Imam Hossein Hospital), Tehran, Iran...
July 2017: Korean Journal of Pain
https://www.readbyqxmd.com/read/28754288/involvement-of-nmda-receptors-in-the-antidepressant-like-effect-of-tramadol-in-the-mouse-forced-swimming-test
#4
Sattar Ostadhadi, Abbas Norouzi-Javidan, Mohsen Chamanara, Reyhaneh Akbarian, Muhammad Imran-Khan, Mehdi Ghasemi, Ahmad-Reza Dehpour
Tramadol is an analgesic agent that is mainly used to treat moderate to severe pain. There is evidence that tramadol may have antidepressant property. However, the mechanisms underlying the antidepressant effects of tramadol have not been elucidated yet. Considering that fact that N-methyl-d-aspartate (NMDA) receptor signaling may play an important role in the pathophysiology of depression, the aim of the present study was to investigate the role of NMDA receptor signaling in the possible antidepressant-like effects of tramadol in the mouse forced swimming test (mFST)...
July 25, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28702984/regenerative-medicine-in-the-treatment-of-gastro-esophageal-reflux-disease-and-laryngo-pharyngeal-reflux-from-research-to-cure
#5
S E Aragona, G Mereghetti, M Bianchetti, B Mangiavillano, T Zurlo, J Lotti, I La Mantia, K França, T Lotti
We present our observational study on 40 patients treated with the medical device containing sodium hyaluronic acid and magnesium alginate, performing a lubricating and hydrating action. This device is in the form of a gel, with topical action to contrast gastroesophageal reflux and to exert a mechanical role of protection of the mucosal tissues (mouth-pharyngo-esophageal mucosa and gastric mucose.). Forty patients were recruited aged between 22- and 72-years-old with painful dyspeptic Gastro Esophageal Reflux Disease (GERD) symptomatology in acute or in clinical phase (25 patients) and with pharyngolaryngo- tracheal symptomatology (15 patients)...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28692411/evaluation-of-the-health-benefits-of-a-multivitamin-multimineral-herbal-essential-oil-infused-supplement-a-pilot-trial
#6
Xuesheng Han, Dennis L Eggett, Tory L Parker
This study was designed to quantitatively evaluate the health benefits of a multivitamin, multimineral, herbal, essential oil-infused supplement using serum biomarkers. We also qualitatively evaluated the health effects of this supplement using a survey. Sixteen participants were recruited to take the supplement as directed for two months. The levels of the following serum components were measured in the participants: total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, triglycerides, lipoprotein(a), LDL/HDL cholesterol ratio, total/HDL cholesterol ratio, ferritin, fibrinogen, C-reactive protein, insulin, testosterone, sex hormone binding globulin, free androgen index, red blood cell magnesium, homocysteine, coenzyme Q10, lipid peroxides, alpha-tocopherol, gamma-tocopherol, cardiovascular index, eicosapentaenoic acid (EPA), arachidonic acid (AA), and the AA/EPA ratio...
July 10, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28691718/additive-and-antagonistic-antinociceptive-interactions-between-magnesium-sulfate-and-ketamine-in-the-rat-formalin-test
#7
Katarina Savić Vujović, Sonja Vučković, Dolika Vasović, Branislava Medić, Nick Knežević, Milica Prostran
Because ketamine and magnesium block NMDA receptor activation by distinct mechanisms of action, we hypothesized that in a model of inflammatory pain in rats the combination of ketamine and magnesium might be more effective than ketamine alone. Antinociceptive activity was assessed by the formalin test in male Wistar rats (200-250 g). Animals were injected with 100 μL of 2.5% formalin to the plantar surface of the right hind paw. Data were recorded as the total time spent in pain-related behavior after the injection of formalin or vehicle (0...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/28682950/baseline-morphine-consumption-may-explain-between-study-heterogeneity-in-meta-analyses-of-adjuvant-analgesics-and-improve-precision-and-accuracy-of-effect-estimates
#8
Brett Doleman, Alex J Sutton, Matthew Sherwin, Jonathan N Lund, John P Williams
BACKGROUND: Statistical heterogeneity can increase the uncertainty of results and reduce the quality of evidence derived from systematic reviews. At present, it is uncertain what the major factors are that account for heterogeneity in meta-analyses of analgesic adjuncts. Therefore, the aim of this review was to identify whether various covariates could explain statistical heterogeneity and use this to improve accuracy when reporting the efficacy of analgesics. METHODS: We searched for reviews using MEDLINE, EMBASE, CINAHL, AMED, and the Cochrane Database of Systematic Reviews...
July 4, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28682182/low-25-hydroxyvitamin-d-and-myofascial-pain-association-of-cancer-colon-polyps-and-tendon-rupture
#9
Jane M Hightower, Kathie M Dalessandri, Karl Pope, Germán T Hernández
BACKGROUND: Myofascial pain that has been associated with cancer and increased risk of morbidity and mortality in cancer patients is intrinsically associated with low magnesium and low 25-hydroxyvitamin D (25(OH)D). Therefore, this physical finding was used as a clinical diagnostic proxy. OBJECTIVE: The objective of this study was to assess the association and prevalence of disease in individuals with myofascial pain and low 25(OH)D in a county with low magnesium in the drinking water...
August 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28670718/ketamine-infusion-combined-with-magnesium-as-a-therapy-for-intractable-chronic-cluster-headache-report-of-two-cases
#10
Xavier Moisset, Pierre Clavelou, Michel Lauxerois, Radhouane Dallel, Pascale Picard
BACKGROUND: Chronic cluster headache (CH) is a rare, highly disabling primary headache condition. As NMDA receptors are possibly overactive in CH, NMDA receptor antagonists, such as ketamine, could be of interest in patients with intractable CH. CASE REPORTS: Two Caucasian males, 28 and 45 years-old, with chronic intractable CH, received a single ketamine infusion (0.5 mg/kg over 2 h) combined with magnesium sulfate (3000 mg over 30 min) in an outpatient setting...
July 3, 2017: Headache
https://www.readbyqxmd.com/read/28660279/mineral-depositions-of-calcifying-skin-disorders-are-predominantly-composed-of-carbonate-apatite
#11
Michael Franzen, Elena Müller-More, Janne Cadamuro, Josef Koller, Wolfgang Salmhofer, Iris Wohlmuth-Wieser, Cornelia Kronberger, Hermann Salmhofer
Subcutaneous calcifications can lead to complications, including pain, inflammation, ulceration and immobilization. Studies on the pathophysiology of mineral compositions and effective treatment modalities are limited. We therefore studied 14 patients with subcutaneous calcifications. Mineral material was collected and analysed by Fourier transform infrared spectrometry. Blood analyses were run to evaluate systemic alterations of mineral metabolism. Carbonate apatite (CAP) was found to be the single constituent in the majority of patients (n = 9, 64...
June 29, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28660084/a-case-of-thermal-esophageal-injury-induced-by-sodium-picosulfate-with-magnesium-citrate
#12
Dong-Hyuk Yang, Byoung Wook Bang, Kye Sook Kwon, Hyung Kil Kim, Yong Woon Shin
Although thermal esophageal injuries caused by hot food or tea have been reported, thermal esophageal injury due to sodium picosulfate with magnesium citrate (PSMC) used for bowel preparation is rarely reported. We report the case of a 56-year-old man who presented with esophageal injury after ingestion of PSMC. Instead of dissolving the PSMC in water before ingestion, he drank water immediately after swallowing PSMC powder. As soon as he drank water, he developed severe chest pain and hematemesis. Upper endoscopy revealed severe hemorrhagic, ulcerative mucosal change from upper to mid-esophagus...
2017: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/28631809/anabolic-steroids-for-treating-pressure-ulcers
#13
REVIEW
Cho Naing, Maxine A Whittaker
BACKGROUND: Pressure ulcers, also known as bed sores, pressure sores or decubitus ulcers develop as a result of a localised injury to the skin or underlying tissue, or both. The ulcers usually arise over a bony prominence, and are recognised as a common medical problem affecting people confined to a bed or wheelchair for long periods of time. Anabolic steroids are used as off-label drugs (drugs which are used without regulatory approval) and have been used as adjuvants to usual treatment with dressings, debridement, nutritional supplements, systemic antibiotics and antiseptics, which are considered to be supportive in healing of pressure ulcers...
June 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28631456/comparison-between-adenosine-and-magnesium-sulphate-as-adjuvants-for-transversus-abdominis-plane-block-a-prospective-randomized-controlled-trial
#14
Amany S Ammar, Khaled M Mahmoud, Zeinab A Kasemy
BACKGROUND: Various adjuvants have been employed during different nerve blocks. We aimed to evaluate the effect of adding adenosine versus magnesium sulfate to bupivacaine on the quality and duration of transversus abdominis plane (TAP) block. METHODS: Participants were randomized to TAP block using either 20 ml of bupivacaine hydrochloride 0.375% + 12 mg adenosine in 2 ml of saline 0.9% (adenosine group), 20 ml of bupivacaine hydrochloride 0.375% + 500 mg magnesium sulphate in 2 ml saline 0...
June 14, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28629437/evaluation-of-a-low-cost-low-power-syringe-pump-to-deliver-magnesium-sulfate-intravenously-to-pre-eclamptic-women-in-a-malawian-referral-hospital
#15
Erica Skerrett, Edward Kommwa, Kelley Maynard, Alexa Juarez, Ronald Mataya, Rebecca Richards-Kortum, Z Maria Oden
BACKGROUND: Magnesium sulfate is an affordable and effective treatment for pre-eclampsia and eclampsia. In settings where infusion pumps are not available to regulate the flow rate of intravenous delivery, healthcare providers must administer magnesium sulfate (MgSO4) via time-consuming and painful, large-volume intramuscular injections. As an alternative to costly commercially available syringe pumps, we developed AutoSyp, an accurate, low-cost, and low-powered syringe pump designed to meet the needs and constraints these low-resource settings...
June 19, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28627205/a-low-fermentable-oligo-di-mono-saccharides-and-polyols-fodmap-diet-is-a-balanced-therapy-for-fibromyalgia-with-nutritional-and-symptomatic-benefits
#16
Ana Paula Marum, Cátia Moreira, Pablo Tomas-Carus, Fernando Saraiva, Catarina Sousa Guerreiro
INTRODUCTION: Fibromyalgia is a chronic rheumatic disease producing widespread pain, associated to a major comorbidity -irritable bowel syndrome. Low FODMAPS diet (low fermentable oligo-di-mono-saccharides and polyols diet) has been effective in controlling irritable bowel syndrome symptoms. Overweight is an aggravating factor for fibromyalgia. We studied effects of low fermentable oligo-di-mono-saccharides and polyols diets on fibromyalgia symptoms and weight status. METHODS: A longitudinal study was performed on 38 fibromyalgia patients using a four-week, repeated assessment as follow: M1 = first assessments/presentation of individual low fermentable oligo-di-mono-saccharides and polyols diet; M2 = second assessments/reintroduction of FODMAPs; M3 = final assessments/nutritional counselling...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28620153/premature-labor-and-neonatal-septicemia-caused-by-capnocytophaga-ochracea
#17
Abdullah A Alhifany, Thamer A Almangour, Deanne E Tabb, David H Levine
BACKGROUND Capnocytophaga ochracea is a gram-negative anaerobic organism commonly found in human oral flora. It is characteristically sensitive to beta-lactams and resistant to aminoglycosides. CASE REPORT A 23-year-old woman presented with lower abdominal pain and was admitted for premature labor at 24-weeks of gestation. At presentation, the cervix was closed and the membrane was intact; however, contractions continued, the membrane subsequently ruptured before receiving any steroids or magnesium, and the mother gave birth to a 540-gram female baby...
June 16, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28598516/intratumor-cisplatin-nephrotoxicity-in-combined-laser-induced-thermal-therapy-for-cancer-treatment
#18
Marcel N Palumbo, Onivaldo Cervantes, Cecilia Eugênio, Flávia T P Hortense, João C Ribeiro, Ana Amélia P Paolini, Antônio C Tedesco, Joel A Sercarz, Marcos B Paiva
INTRODUCTION: Thermal ablation of tumors by Nd:YAG laser has been growing as a multidisciplinary subspecialty defined as laser-induced thermal therapy (LITT), and has been increasingly accepted as a minimally invasive method for palliation of advanced or recurrent cancer. Previous studies have shown that adjuvant chemotherapy can potentiate laser thermal ablation of tumors leading to improved palliation in advanced cancer patients. OBJECTIVE: Evaluate nephrotoxicity by early markers of renal function in treating head and neck cancer using intra-tumor injections of cisplatin combined with laser-induced thermal therapy (CDDP-LITT)...
June 9, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28582812/symptomatic-efficacy-of-buckwheat-products-in-non-celiac-gluten-sensitivity-ncgs
#19
Monicau Dinu, Donatella Macchia, Giuditta Pagliai, Anna Maria Gori, Francesca Cesari, Rossella Marcucci, Francesco Sofi, Alessandro Casini
BACKGROUND AND OBJECTIVES: Buckwheat (Fagopyrum esculentum) is a gluten-free grain with acclaimed benefi-cial effects on human health. Our aim was to assess the effect of buckwheat products on intestinal/extra-intestinal symptoms and biochemical parameters in patients with Non-Celiac Gluten Sensitivity (NCGS). METHODS AND STUDY DESIGN: A randomized, crossover trial with two intervention phases was conducted on 19 NCGS patients over a 12 week-period. The participants were assigned to consume products made from buckwheat or to maintain their normal gluten-free diet for 6 weeks in a random order...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28500682/red-blood-cell-transfusions-during-sickle-cell-anemia-vaso-occlusive-crises-a-report-from-the-magnesium-in-crisis-magic-study
#20
Monica L Hulbert, Julie A Panepinto, J Paul Scott, Robert I Liem, Lawrence J Cook, Timothy Simmons, David C Brousseau
BACKGROUND: Little is known about red blood cell (RBC) transfusion practices for children hospitalized for a sickle cell vaso-occlusive pain crisis (VOC). We hypothesized that transfusion would be associated with the development of acute chest syndrome (ACS), lower hemoglobin (Hb) concentration, and lack of hydroxyurea therapy. STUDY DESIGN AND METHODS: This is a secondary analysis of all children admitted for a sickle cell pain crisis enrolled in the Magnesium in Crisis (MAGiC) randomized trial; all had HbSS or S-β(0) thalassemia...
August 2017: Transfusion
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