keyword
https://read.qxmd.com/read/38519041/role-of-ductus-venosus-doppler-sonography-for-the-prediction-of-perinatal-outcome-in-term-pregnancies-complicated-by-gestational-diabetes-mellitus
#1
JOURNAL ARTICLE
Oliver Graupner, Caroline Rath, Linda Lecker, Monica Ritter, Jochen Ritgen, Christian Enzensberger
PURPOSE: Ductus venosus (DV) Doppler velocimetry reflects fetal cardiac function. Gestational diabetes mellitus (GDM) is assumed to impair cardiac function due to fetal hyperglycemia. The purpose of this study was to assess the ability of DV Doppler to predict an adverse perinatal outcome (APO) in term pregnancies with GDM. METHODS: This is a retrospective cohort study including GDM pregnancies of singleton, non-anomalous fetuses without any signs of placental dysfunction...
March 22, 2024: Zeitschrift Für Geburtshilfe und Neonatologie
https://read.qxmd.com/read/38514154/cardiac-fibroma-presenting-as-hypoplastic-left-heart-syndrome-in-a-foetus-causal-or-coincidental
#2
JOURNAL ARTICLE
Abinaya Sundari, Umamaheshwari Gurusamy
Primary cardiac tumours are very rare. Cardiac tumours in the perinatal period are even more uncommon with a prevalence of 0.0017% to 0.28% in autopsy series. The majority of benign cardiac tumours are cardiac rhabdomyomas, followed by cardiac fibromas. Another rare congenital heart disease is hypoplastic left heart syndrome (HLHS). Here we present a 21-week-old foetus diagnosed antenatally with HLHS on foetal echocardiogram. An autopsy done on the foetus following medical termination of pregnancy revealed a cardiac fibroma in the ventricular septum...
March 21, 2024: BMJ Case Reports
https://read.qxmd.com/read/38513885/rates-of-reproductive-counseling-and-contraception-use-in-patients-with-heart-failure-at-a-tertiary-care-center
#3
JOURNAL ARTICLE
Kristen E Wong, Amanda K Verma
BACKGROUND: Increasing numbers of women of childbearing age have cardiac disease including heart failure. In these women, pregnancy can cause significant morbidity and mortality. Contraceptive use and pregnancy counseling in women with heart failure is an essential part of their medical care. Here, we assess contraceptive use and pregnancy counseling of patients with heart failure at a single tertiary care center. METHODS: This was a retrospective, single-center cohort study of female patients with heart failure with reduced ejection fraction, LVADs, and heart transplants who were seen in the adult Advanced Heart Failure outpatient clinics...
March 19, 2024: Journal of Cardiac Failure
https://read.qxmd.com/read/38512489/congenitally-corrected-transposition-of-the-great-arteries-in-utero-morphological-spectrum-outcomes-and-pitfalls-in-fetal-diagnosis
#4
JOURNAL ARTICLE
Maria Kavga, Adeolu Banjoko, Esther Poole, John Stickley, Tarak Desai, Paul Miller, Michael Harris, Adrian Crucean, Natasha Khan, Anna N Seale
Congenitally corrected transposition of the great arteries (ccTGA) is a rare malformation with diverse morphology. We assessed features of fetuses with ccTGA and evaluated neonatal and pediatric outcomes. This was a retrospective review of fetuses with ccTGA at Birmingham Women's and Children's Hospital born from 2005 to 2019. Of thirty-six fetuses identified, six had unavailable prenatal data, one was postnatally diagnosed with isomerism and 29 fetuses were evaluated. ccTGA without associated cardiac lesions was found in 28% (8/29), ccTGA with significant VSD in 31% (9/29), ccTGA with pulmonary obstruction in 24% (7/29) and ccTGA with complex anomalies in 17% (5/29)...
March 21, 2024: Pediatric Cardiology
https://read.qxmd.com/read/38511279/epidemiological-survey-of-congenital-heart-disease-among-children-aged-from-2-to-18-in-suo-county-nagqu-tibet
#5
JOURNAL ARTICLE
Tian Lin, Huaping Jia, Yunming Li, Yongxing Xu, Bei Zhao, Dong Zheng, Hongfeng Yan, Meihui Zhao, Yanlei Li, Liping Xia, Fengxia Zhou, Cuiping Liu, Ke Ma, Ma Mi, Jianwen Gu
Lin, Tian, Huaping Jia, Yunming Li, Yongxing Xu, Bei Zhao, Dong Zheng, Hongfeng Yan, Meihui Zhao, Yanlei Li, Liping Xia, Fengxia Zhou, Cuiping Liu, Ke Ma, Ma Mi, and Jianwen Gu. Epidemiological survey of congenital heart disease among children aged from 2 to 18 in Suo County, Nagqu, Tibet. High Alt Med Biol . 00:000-000, 2024. Background: Studies have reported the prevalence of congenital heart disease (CHD) in parts of Tibet, but relative epidemiological surveys are rare. We aimed to explore the prevalence of CHD in children and its relationship with family history in Suo County, Nagqu, Tibet, an altitude of 3,980 meters...
March 21, 2024: High Altitude Medicine & Biology
https://read.qxmd.com/read/38505753/reprogramming-of-the-developing-heart-by-hif1a-deficient-sympathetic-system-and-maternal-diabetes-exposure
#6
JOURNAL ARTICLE
Hana Kolesova, Petra Hrabalova, Romana Bohuslavova, Pavel Abaffy, Valeria Fabriciova, David Sedmera, Gabriela Pavlinkova
INTRODUCTION: Maternal diabetes is a recognized risk factor for both short-term and long-term complications in offspring. Beyond the direct teratogenicity of maternal diabetes, the intrauterine environment can influence the offspring's cardiovascular health. Abnormalities in the cardiac sympathetic system are implicated in conditions such as sudden infant death syndrome, cardiac arrhythmic death, heart failure, and certain congenital heart defects in children from diabetic pregnancies...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38498256/concurrent-spontaneous-coronary-dissection-and-reversible-cerebral-vasoconstriction-syndrome-during-postnatal-care
#7
JOURNAL ARTICLE
Sang Gon Yoon, Yeo-Jeong Song, Yun-Seok Song, Jino Park, Seunghwan Kim, Dong-Kie Kim, Ki-Hun Kim, Doo-Il Kim, Hyun Kuk Kim, Dong Ah Lee
BACKGROUND: Pregnancy-associated spontaneous coronary artery dissection (SCAD) and reversible cerebral vasoconstriction syndrome (RCVS) are rare conditions that may occur during pregnancy and the postpartum period. The coexistence of both diseases may pose a risk to patients, potentially resulting in a variety of complications and clinical manifestations. This is considered the first case of a patient who successfully recovered from a critical condition in the postpartum period, with contemporaneous SCAD and RCVS...
March 18, 2024: Egyptian Heart Journal: EHJ
https://read.qxmd.com/read/38496439/coronary-microvascular-function-following-severe-preeclampsia
#8
Michael C Honigberg, Katherine E Economy, Maria A Pabón, Xiaowen Wang, Claire Castro, Jenifer M Brown, Sanjay Divakaran, Brittany N Weber, Leanne Barrett, Anna Perillo, Anina Y Sun, Tajmara Antoine, Faranak Farrohi, Brenda Docktor, Emily S Lau, Doreen DeFaria Yeh, Pradeep Natarajan, Amy A Sarma, Robert M Weisbrod, Naomi M Hamburg, Jennifer E Ho, Jason D Roh, Malissa J Wood, Nandita S Scott, Marcelo F Di Carli
BACKGROUND: Preeclampsia is a pregnancy-specific hypertensive disorder associated with an imbalance in circulating pro- and anti-angiogenic proteins. Preclinical evidence implicates microvascular dysfunction as a potential mediator of preeclampsia-associated cardiovascular risk. METHODS: Women with singleton pregnancies complicated by severe antepartum-onset preeclampsia and a comparator group with normotensive deliveries underwent cardiac positron emission tomography (PET) within 4 weeks of delivery...
March 5, 2024: medRxiv
https://read.qxmd.com/read/38495666/the-impact-of-pregnancy-in-patients-with-thoracic-aortic-disease-epidemiology-risk-assessment-and-management-considerations
#9
REVIEW
Valeria E Duarte, Jessica N Richardson, Michael N Singh
Thoracic aortic disease (TAD) poses substantial risks during pregnancy, particularly for women with genetic conditions such as Marfan syndrome, Loeys-Dietz syndrome, and vascular Ehlers-Danlos syndrome. This review examines the epidemiology, risk assessment, and management of TAD in pregnancy. Preconception counseling is vital considering the hereditary nature of TAD and potential pregnancy-related complications. Genetic testing and imaging surveillance aid in risk assessment. Medical management, including beta-blockade and strict blood pressure control, is essential throughout pregnancy...
2024: Methodist DeBakey Cardiovascular Journal
https://read.qxmd.com/read/38495662/high-risk-congenital-heart-disease-in-pregnancy
#10
REVIEW
Saurabh Rajpal, Carla P Rodriguez
High-risk congenital heart disease (CHD) in pregnancy presents a complex clinical challenge. With improved medical care and increased survival rates, a growing population of adults with complex CHD are surviving to adulthood, including women of reproductive age. This chapter focuses on risk stratification and management of pregnant women with high-risk CHD, emphasizing the importance of considering both anatomical and physiological complexity. Maternal physiological changes, such as blood volume increase, cardiac output changes, and alterations in vascular resistance, can significantly impact high-risk CHD patients...
2024: Methodist DeBakey Cardiovascular Journal
https://read.qxmd.com/read/38495661/cardiomyopathies-in-women
#11
REVIEW
Cindy M Martin
Heart failure affects over 2.6 million people in the United States. While women have better overall survival rates, they also suffer from higher morbidity as shown by higher rates of hospitalization and worse quality of life. Several anatomical differences in women's hearts affect both systolic and diastolic cardiac physiology. Despite these findings, women are significantly underrepresented in clinical trials, necessitating extrapolation of data from males. Because women have sex-specific etiologies of heart failure and unique manifestations in genetic-related cardiomyopathies, meaningful sex-related differences affect heart failure outcomes as well as access to and outcomes in advanced heart failure therapies in women...
2024: Methodist DeBakey Cardiovascular Journal
https://read.qxmd.com/read/38495654/an-overview-of-arrhythmias-in-pregnancy
#12
REVIEW
Kamala P Tamirisa, Estefania Oliveros, Shweta Paulraj, Adriana C Mares, Annabelle Santos Volgman
Cardiovascular disease significantly jeopardizes pregnancies in the United States, impacting 1% to 4% of pregnancies annually. Among complications, cardiac arrhythmias are prevalent, posing concerns for maternal and fetal health. The incidence of arrhythmias during pregnancy is rising, partly due to advances in congenital heart surgery and a growing population of women with structural heart disease. While most arrhythmias are benign, the increasing prevalence of more serious arrhythmias warrants a proactive approach...
2024: Methodist DeBakey Cardiovascular Journal
https://read.qxmd.com/read/38492326/impaired-ischemia-reperfusion-responses-in-the-hearts-of-aged-male-and-female-offspring-of-obese-rats
#13
JOURNAL ARTICLE
Carlos A Ibáñez, Francisco Correa, Gabriela Lira-León, Luis A Reyes-Castro, Francisco Javier Roldán, Alejandro Silva-Palacios, Mabel Buelna-Chontal, Guadalupe L Rodríguez-González, Peter W Nathanielsz, Cecilia Zazueta, Elena Zambrano
Maternal obesity predisposes offspring (F1) to cardiovascular disease. To evaluate basal heart function and ischemia-reperfusion (IR) responses in F1 males and females of obese mothers, female Wistar rats (F0) were fed chow or an obesogenic (MO) diet from weaning through pregnancy and lactation. Non-sibling F1 males and females were weaned to chow at postnatal day (PND) 21 and euthanized at PND 550. Offspring of MO mothers (MOF1) rarely survive beyond PND 650. Hearts were immediately isolated from euthanized F1s and subjected to 30 min ischemia with 20 min reperfusion...
March 15, 2024: Archives of Medical Research
https://read.qxmd.com/read/38489018/prenatal-detection-rates-for-congenital-heart-disease-using-abnormal-obstetrical-screening-ultrasound-alone-as-indication-for-fetal-echocardiography
#14
JOURNAL ARTICLE
Sanjay Vepa, Mubarika Alavi, Weilu Wu, Julie Schmittdiel, Lisa J Herrinton, Kavin Desai
OBJECTIVE: To determine the live born prenatal detection rate of significant congenital heart disease (CHD) in a large, integrated, multi-center community-based health system using a strategy of referral only of patients with significant cardiac abnormalities on obstetrical screening ultrasound for fetal echocardiography. Detection rates were assessed for screening in both radiology and maternal fetal medicine (MFM). The impact on fetal echocardiography utilization was also assessed. METHODS: This was a retrospective cohort study using an electronic health record, outside claims databases and chart review to determine all live births between 2016 and 2020 with postnatally confirmed sCHD that were prenatally detectable and resulted in cardiac surgery, intervention, or death within 1 year...
March 15, 2024: Prenatal Diagnosis
https://read.qxmd.com/read/38487046/designing-a-multidisciplinary-cardio-obstetrics-curriculum-for-general-cardiology-and-obstetrics-residents-a-national-survey-of-educational-needs
#15
JOURNAL ARTICLE
Sarah Blissett, Lotus Alphonsus, Genevieve Eastabrook, Harrison Banner, Samuel C Siu
BACKGROUND: The increasing and potentially preventable cardiac events in pregnant patients have led to calls to enhance multidisciplinary cardio-obstetrics education. To design a multidisciplinary cardio-obstetrics curriculum for general cardiology and obstetrics and gynecology (OBGYN) residents, we need to define educational needs from the perspectives of both cardiology and OBGYN residents. Our study characterizes the educational needs of Canadian cardiology and OBGYN residents. METHODS: Canadian cardiology and OBGYN residents were surveyed on clinical exposures, perceived needs for topics, unperceived needs for topics (multiple-choice questions) and preferences for educational formats...
February 2024: CJC open
https://read.qxmd.com/read/38485554/maternal-and-neonatal-outcomes-in-women-with-congenital-heart-disease-a-nationwide-population-based-study
#16
JOURNAL ARTICLE
Kuan-Miao Lin, Yun-Hsuan Yang, Chuan-Pin Lee, Ko-Jung Chen, Yao-Hsu Yang, Jiunn-Ming Sheen, Shao-Ju Chien
BACKGROUND: We evaluated the outcomes of pregnancy in women with congenital heart disease (CHD) and their offspring in Taiwan. We also investigated how different severity levels may influence the outcomes. METHODS: We used data (2009-2017) from the Birth Certificate Application database in Taiwan, which is linked to the National Health Insurance Research Database and Taiwan Maternal and Child Health Database. We identified 2990 women with CHD who had 4227 births...
March 13, 2024: Journal of the Formosan Medical Association
https://read.qxmd.com/read/38485322/genotype-phenotype-correlations-in-a-fetus-with-kleefstra-syndrome
#17
Xuezhen Wang, Jiebin Wu, Min Pang, Ying Liu, Jingfang Zhai
OBJECTIVE: Kleefstra syndrome (KS), formerly known as 9q subtelomeric deletion syndrome, is characterized by multiple structural abnormalities. However, most fetuses do not have obvious abnormal phenotypes. In this study, the fetus with KS presented with multiple system structural anomalies, and we aimed to explore the genotype-phenotype correlations of KS fetuses. CASE REPORT: Multiple systematic structural anomalies, including severe intrauterine growth restriction (IUGR) and cardiac defects, were detected by ultrasound in the fetus at 33 + 5 weeks' gestation...
March 2024: Taiwanese Journal of Obstetrics & Gynecology
https://read.qxmd.com/read/38485311/syndromic-and-single-gene-disorders-associated-with-fetal-pleural-effusion-i-noonan-syndrome-rasopathy-and-congenital-lymphatic-anomalies
#18
REVIEW
Chih-Ping Chen
Fetal pleural effusion has been reported to be associated with chromosomal abnormalities, genetic syndromes, obstructive uropathy, lymphatic vessel abnormalities such as Noonan syndrome, RASopathy and congenital lymphatic anomalies, thoracic cavity defects, Rh or ABO incompatibility, non-immune hydrops fetalis, infections, congenital cardiac anomalies, metabolic diseases and hematologic diseases such as α-thalassemia. This review provides an overview of syndromic and single gene disorders associated with fetal pleural effusion that is useful for genetic counseling and fetal therapy at prenatal diagnosis of fetal pleural effusion...
March 2024: Taiwanese Journal of Obstetrics & Gynecology
https://read.qxmd.com/read/38485310/chromosomal-abnormalities-associated-with-fetal-pleural-effusion-ii-specific-and-non-specific-chromosome-aberrations
#19
REVIEW
Chih-Ping Chen
Fetal pleural effusion has been reported to be associated with chromosomal abnormalities, genetic syndromes, obstructive uropathy, lymphatic vessel abnormalities such as Noonan syndrome, RASopathy and congenital lymphatic anomalies, thoracic cavity defects, Rh or ABO incompatibility, non-immune hydrops fetalis, infections, congenital cardiac anomalies, metabolic diseases and hematologic diseases such as α-thalassemia. This review provides a comprehensive view of specific and non-specific chromosome aberrations associated with fetal pleural effusion which is useful for genetic counseling and fetal therapy at prenatal diagnosis of fetal pleural effusion...
March 2024: Taiwanese Journal of Obstetrics & Gynecology
https://read.qxmd.com/read/38485309/chromosomal-abnormalities-associated-with-fetal-pleural-effusion-i-general-overview
#20
REVIEW
Chih-Ping Chen
Fetal pleural effusion has been reported to be associated with chromosomal abnormalities, genetic syndromes, obstructive uropathy, lymphatic vessel abnormalities such as Noonan syndrome, RASopathy and congenital lymphatic anomalies, thoracic cavity defects, Rh or ABO incompatibility, non-immune hydrops fetalis, infections, congenital cardiac anomalies, metabolic diseases and hematologic diseases such as α-thalassemia. This review provides an overview of chromosomal abnormalities associated with fetal pleural effusion which is useful for genetic counseling and fetal therapy at prenatal diagnosis of fetal pleural effusion...
March 2024: Taiwanese Journal of Obstetrics & Gynecology
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