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https://www.readbyqxmd.com/read/28336268/malaria-incidence-during-early-childhood-in-rural-burkina-faso-analysis-of-a-birth-cohort-protected-with-insecticide-treated-mosquito-nets
#1
Sabrina Wehner, Gabriele Stieglbauer, Corneille Traoré, Ali Sie, Heiko Becher, Olaf Müller
BACKGROUND: Even in the high transmission areas of sub-Saharan Africa (SSA), the incidence of falciparum malaria varies greatly depending on factors such as age, rainfall pattern, distance to breeding places, quality of houses, and existing vector control measures. Insecticide-treated mosquito nets (ITN) have now become the vector control standard in nearly all of SSA. This study aims to describe and analyse the incidence of malaria in a cohort of young children protected with ITN in rural West Africa...
March 20, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28336155/emergency-nurses-perceptions-of-emergency-department-preparedness-for-an-ebola-outbreak-a-qualitative-descriptive-study
#2
Mihirika Sds Pincha Baduge, Cheryle Moss, Julia Morphet
BACKGROUND: Ebola Virus Disease is highly contagious and has high mortality. In 2014, when the outbreak in West Africa was declared a public health emergency, emergency departments in Australia commenced preparation and vigilance for people presenting with ebola like symptoms, to limit spread of the disease. RESEARCH AIM: To examine Australian emergency nurses' perceptions regarding their own and their emergency departments' preparedness to manage an ebola outbreak...
March 20, 2017: Australasian Emergency Nursing Journal: AENJ
https://www.readbyqxmd.com/read/28334680/assessing-driving-forces-of-land-use-and-land-cover-change-by-a-mixed-method-approach-in-north-eastern-ghana-west-africa
#3
Janina Kleemann, Gülendam Baysal, Henry N N Bulley, Christine Fürst
Land use and land cover change (LULCC) is the result of complex human-environmental interactions. The high interdependencies in social-ecological systems make it difficult to identify the main drivers. However, knowledge of key drivers of LULCC, including indirect (underlying) drivers which cannot be easily determined by spatial or economic analyses, is essential for land use planning and especially important in developing countries. We used a mixed-method approach in order to detect drivers of LULCC in the Upper East Region of northern Ghana by different qualitative and quantitative methods which were compared in a confidence level analysis...
March 20, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28332466/towards-a-coherent-global-framework-for-health-financing-recommendations-and-recent-developments
#4
Trygve Ottersen, Riku Elovainio, David B Evans, David McCoy, Di Mcintyre, Filip Meheus, Suerie Moon, Gorik Ooms, John-Arne Røttingen
The articles in this special issue have demonstrated how unprecedented transitions have come with both challenges and opportunities for health financing. Against the background of these challenges and opportunities, the Working Group on Health Financing at the Chatham House Centre on Global Health Security laid out, in 2014, a set of policy responses encapsulated in 20 recommendations for how to make progress towards a coherent global framework for health financing. These recommendations pertain to domestic financing of national health systems, global public goods for health, external financing for national health systems and the cross-cutting issues of accountability and agreement on a new global framework...
April 2017: Health Economics, Policy, and Law
https://www.readbyqxmd.com/read/28331604/re-establishing-the-pecking-order-niche-models-reliably-predict-suitable-habitats-for-the-reintroduction-of-red-billed-oxpeckers
#5
Riddhika Kalle, Leigh Combrink, Tharmalingam Ramesh, Colleen T Downs
Distributions of avian mutualists are affected by changes in biotic interactions and environmental conditions driven directly/indirectly by human actions. The range contraction of red-billed oxpeckers (Buphagus erythrorhynchus) in South Africa is partly a result of the widespread use of acaracides (i.e., mainly cattle dips), toxic to both ticks and oxpeckers. We predicted the habitat suitability of red-billed oxpeckers in South Africa using ensemble models to assist the ongoing reintroduction efforts and to identify new reintroduction sites for population recovery...
March 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28331412/a-review-of-the-pseudobarbus-afer-peters-1864-species-complex-teleostei-cyprinidae-in-the-eastern-cape-fold-ecoregion-of-south-africa
#6
Albert Chakona, Paul H Skelton
The Eastern Cape redfin, Pseudobarbus afer, has long been considered to be a single widespread and variable species occurring in multiple isolated river systems in the Cape Fold Ecoregion (CFE) at the southern tip of Africa. Mitochondrial cytochrome b and control region sequence data of individuals from populations currently assigned to Pseudobarbus afer across the species' distribution range revealed existence of four deeply divergent taxonomic units: (i) the Mandela lineage confined to the Sundays, Swartkops and Baakens river systems, (ii) the Krom lineage endemic to the Krom River system, (iii) the St Francis lineage occurring in the Gamtoos and adjacent river systems, and (iv) the Forest lineage occurring in several coastal river systems from the Tsitsikamma to the Klein Brak River system...
2017: ZooKeys
https://www.readbyqxmd.com/read/28331386/phylogenetic-analysis-of-the-genus-laparocerus-with-comments-on-colonisation-and-diversification-in-macaronesia-coleoptera-curculionidae-entiminae
#7
Antonio Machado, Eduardo Rodríguez-Expósito, Mercedes López, Mariano Hernández
The flightless Entiminae weevil genus Laparocerus is the species-richest genus, with 237 species and subspecies, inhabiting Macaronesia (Madeira archipelago, Selvagens, Canary Islands) and the continental 'Macaronesian enclave' in Morocco (one single polytypic species). This is the second contribution to gain insight of the genus and assist in its systematic revision with a mitochondrial phylogenetic analysis. It centres on the Canarian clade, adding the 12S rRNA gene to the combined set of COII and 16S rRNA used in our first contribution on the Madeiran clade (here re-analysed)...
2017: ZooKeys
https://www.readbyqxmd.com/read/28331092/monkeypox-virus-host-factor-screen-in-haploid-cells-identifies-essential-role-of-garp-complex-in-extracellular-virus-formation
#8
Susan Realegeno, Andreas S Puschnik, Amrita Kumar, Cynthia Goldsmith, Jillybeth Burgado, Suryaprakash Sambhara, Victoria A Olson, Darin Carroll, Inger Damon, Tetsuya Hirata, Taroh Kinoshita, Jan E Carette, Panayampalli Subbian Satheshkumar
Monkeypox virus (MPXV) is a human pathogen that is a member of the Orthopoxvirus genus, which includes Vaccinia virus and Variola virus (the causative agent of smallpox). Human monkeypox is considered an emerging zoonotic infectious disease. To identify host factors required for MPXV infection, we performed a genome-wide insertional mutagenesis screen in human haploid cells. The screen revealed several candidate genes, including those involved in Golgi trafficking, glycosaminoglycan biosynthesis and glycosylphosphatidylinositol (GPI) - anchor biosynthesis...
March 22, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28323837/lion-trophy-hunting-in-west-africa-a-response-to-bouch%C3%A3-et-al
#9
H Bauer, P Henschel, C Packer, C Sillero-Zubiri, B Chardonnet, E A Sogbohossou, H H De Iongh, D W Macdonald
No abstract text is available yet for this article.
2017: PloS One
https://www.readbyqxmd.com/read/28322693/influence-of-referral-pathway-on-ebola-virus-disease-case-fatality-rate-and-effect-of-survival-selection-bias
#10
Frauke Rudolf, Mads Damkjær, Suzanne Lunding, Kenn Dornonville de la Cour, Alyssa Young, Tim Brooks, Tom Sesay, Alex P Salam, Sharmistha Mishra, Merete Storgaard
Case-fatality rates in Ebola treatment centers (ETCs) varied widely during the Ebola virus disease (EVD) outbreak in West Africa. We assessed the influence of referral pathway on ETC case-fatality rates with a retrospective cohort of 126 patients treated at the Mathaska ETC in Port Loko, Sierra Leone. The patients consisted of persons who had confirmed EVD when transferred to the ETC or who had been diagnosed onsite. The case-fatality rate for transferred patients was 46% versus 67% for patients diagnosed onsite (p = 0...
April 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28320055/global-trends-in-esophageal-cancer
#11
Gautam K Malhotra, Ujwal Yanala, Advaitaa Ravipati, Matthew Follet, M Vijayakumar, Chandrakanth Are
BACKGROUND AND OBJECTIVES: Esophageal Cancer (EC) is a lethal malignancy with poor prognosis and significant variations in the incidence, mortality, and histopathology based on geographic regions. The aim of this study was to quantitatively analyze these variations to identify patterns and areas for further research. METHODS: We utilized the GLOBOCAN 2012, and Cancer Incidence in five Continents, Volume X (CI5X) database to analyze variations in EC incidence and mortality...
March 20, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28317032/first-report-of-the-east-african-kdr-mutation-in-an-anopheles-gambiae-mosquito-in-c%C3%A3-te-d-ivoire
#12
Mouhamadou Chouaïbou, Fodjo Behi Kouadio, Emmanuel Tia, Luc Djogbenou
Background. The intensive use of insecticides in public health and agriculture has led to the development of insecticide resistances in malaria vectors across sub-Saharan Africa countries in the last two decades. The kdr target site point mutation which is among the best characterised resistance mechanisms seems to be changing its distribution patterns on the African continent. The 1014F  kdr mutation originally described only in West Africa is spreading to East Africa while the 1014S  kdr mutation originally described in East Africa, is spreading to West and Central Africa...
February 9, 2017: Wellcome Open Res
https://www.readbyqxmd.com/read/28314488/building-sustainable-local-capacity-for-global-health-research-in-west-africa
#13
Nadia A Sam-Agudu, Elijah Paintsil, Muktar H Aliyu, Awewura Kwara, Folasade Ogunsola, Yaw A Afrane, Chima Onoka, Gordon A Awandare, Gladys Amponsah, Llewellyn J Cornelius, Gabou Mendy, Rachel Sturke, Anita Ghansah, George K Siberry, Echezona E Ezeanolue
BACKGROUND: Global health research in resource-limited countries has been largely sponsored and led by foreign institutions. Thus, these countries' training capacity and productivity in global health research is limited. Local participation at all levels of global health knowledge generation promotes equitable access to evidence-based solutions. Additionally, leadership inclusive of competent local professionals promotes best outcomes for local contextualization and implementation of successful global health solutions...
November 2016: Annals of Global Health
https://www.readbyqxmd.com/read/28306534/ameliorative-potential-of-blighia-sapida-k-d-koenig-bark-against-pancreatic-%C3%AE-cell-dysfunction-in-alloxan-induced-diabetic-rats
#14
Oluwafemi Adeleke Ojo, Basiru Olaitan Ajiboye, Adebola Busola Ojo, Babatunji Emmanuel Oyinloye, Oluwatosin Debbie Imiere, Oluwatosin Adeyonu
Background In West Africa, the fruit, seed, leaf and stem of Blighia sapida K.D. Koenig are commonly used as remedy against a variety of diseases, including diabetes mellitus. This study investigated the ameliorative potential of B. sapida K.D. Koenig stem bark ethanol extract against pancreatic β-cell dysfunction in diabetic rats. Methods Diabetes was induced by intraperitoneal injection of alloxan (65 mg/kg body weight) for 21 days, and orally administered with glibenclamide (5 mg/kg body weight), 50-150 mg/kg body weight of B...
March 17, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28306518/biochemical-testing-in-a-laboratory-tent-and-semi-intensive-care-of-ebola-patients-on-site-in-a-remote-part-of-guinea-a-paradigm-shift-based-on-a-bleach-sensitive-point-of-care-device
#15
Leonid M Irenge, Jean-Michel Dindart, Jean-Luc Gala
BACKGROUND: During the West Africa Ebola virus disease (EVD) outbreak, a Belgian laboratory was deployed for supporting the Ebola treatment unit (ETU) of N'Zerekore, Guinea. Besides diagnosis of EVD and malaria, biochemical parameters were tested and used to guide supportive treatment of EVD. METHODS: To preserve analytes stability, lithium-heparin blood samples were analyzed using the i-STAT® point-of-care testing (POCT) handheld device without the viral inactivation step...
March 15, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28303774/physiological-evaluation-of-personal-protective-ensembles-recommended-for-use-in-west-africa
#16
Aitor Coca, Tyler Quinn, Jung-Hyun Kim, Tianzhou Wu, Jeff Powell, Raymond Roberge, Ronald Shaffer
OBJECTIVE: Personal protective equipment (PPE) provides health care workers with a barrier to prevent human contact with viruses like Ebola and potential transmission of the disease. However, PPE can also introduce an additional physiological burden from potentially increased heat stress. This study evaluated the human physiological and subjective responses to continuous light exercise within environmental conditions similar to those in West Africa while wearing 3 different, commonly used PPE ensembles (E1, E2, and E3)...
March 17, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28303772/physiological-evaluation-of-cooling-devices-in-conjunction-with-personal-protective-ensembles-recommended-for-use-in-west-africa
#17
Tyler Quinn, Jung-Hyun Kim, Amanda Strauch, Tianzhou Wu, Jeffery Powell, Raymond Roberge, Ronald Shaffer, Aitor Coca
OBJECTIVE: Cooling devices (CDs) worn under personal protective equipment (PPE) can alleviate some of the heat stress faced by health care workers responding to the Ebola outbreak in West Africa. METHODS: Six healthy, young individuals were tested while wearing 4 different CDs or no cooling (control) under PPE in an environmental chamber (32°C/92% relative humidity) while walking (3 METs, 2.5 mph, 0% grade) on a treadmill for 60 minutes. Exercise was preceded by a 15-minute stabilization period and a 15-minute donning period...
March 17, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28302553/stark-regional-and-sex-differences-in-the-prevalence-and-awareness-of-hypertension-an-h3africa-awi-gen-study-across-6-sites-in-sub-saharan-africa
#18
F Xavier Gómez-Olivé, Stuart A Ali, Felix Made, Catherine Kyobutungi, Engelbert Nonterah, Lisa Micklesfield, Marianne Alberts, Romuald Boua, Scott Hazelhurst, Cornelius Debpuur, Felistas Mashinya, Sekgothe Dikotope, Hermann Sorgho, Ian Cook, Stella Muthuri, Cassandra Soo, Freedom Mukomana, Godfred Agongo, Christopher Wandabwa, Sulaimon Afolabi, Abraham Oduro, Halidou Tinto, Ryan G Wagner, Tilahun Haregu, Alisha Wade, Kathleen Kahn, Shane A Norris, Nigel J Crowther, Stephen Tollman, Osman Sankoh, Michèle Ramsay
BACKGROUND: There is a high prevalence of hypertension and related cardiovascular diseases in sub-Saharan Africa, yet few large studies exploring hypertension in Africa are available. The actual burden of disease is poorly understood and awareness and treatment to control it is often suboptimal. OBJECTIVES: The study sought to report the prevalence of measured hypertension and to assess awareness and control of blood pressure among older adults in rural and urban settings in 6 sites located in West, East, and Southern Africa...
March 13, 2017: Global Heart
https://www.readbyqxmd.com/read/28302552/exploring-overlaps-between-the-genomic-and-environmental-determinants-of-lvh-and-stroke-a-multicenter-study-in-west-africa
#19
Abiodun M Adeoye, Bruce Ovbiagele, Philip Kolo, Lambert Appiah, Akinyemi Aje, Oladimeji Adebayo, Fred Sarfo, Joshua Akinyemi, Gregory Adekunle, Francis Agyekum, Vincent Shidali, Okechukwu Ogah, Dan Lackland, Mulugeta Gebregziabher, Donna Arnett, Hemant K Tiwari, Rufus Akinyemi, Ojo Olakanmi Olagoke, Ayodipupo Sikiru Oguntade, Taiwo Olunuga, Kelechi Uwanruochi, Carolyn Jenkins, Patrick Adadey, Henry Iheonye, Lukman Owolabi, Reginald Obiako, Samuel Akinjopo, Kevin Armstrong, Albert Akpalu, Adekunle Fakunle, Raelle Saulson, Mayowa Aridegbe, Paul Olowoyo, Godwin Osaigbovo, Josephine Akpalu, Bimbo Fawale, Philip Adebayo, Oyedunni Arulogun, Philip Ibinaiye, Atinuke Agunloye, Naser Ishaq, Kolawole Wahab, Onoja Akpa, Omisore Adeleye, Andrew Bock-Oruma, Godwin Ogbole, Sylvia Melikam, Joseph Yaria, Luqman Ogunjimi, Abdul Salaam, Taofiki Sunmonu, Akintomiwa Makanjuola, Temitope Farombi, Ruth Laryea, Ezinne Uvere, Salaam Kehinde, Innocent Chukwuonye, Paschal Azuh, Morenikeji Komolafe, Adeseye Akintunde, Olugbo Obiabo, Olusegun Areo, Issa Kehinde, Adeniyi G Amusa, Mayowa Owolabi
BACKGROUND: Whether left ventricular hypertrophy (LVH) is determined by similar genomic and environmental risk factors with stroke, or is simply an intermediate stroke marker, is unknown. OBJECTIVES: We present a research plan and preliminary findings to explore the overlap in the genomic and environmental determinants of LVH and stroke among Africans participating in the SIREN (Stroke Investigative Research and Education Network) study. METHODS: SIREN is a transnational, multicenter study involving acute stroke patients and age-, ethnicity-, and sex-matched control subjects recruited from 9 sites in Ghana and Nigeria...
March 13, 2017: Global Heart
https://www.readbyqxmd.com/read/28302420/a-cryptic-mitochondrial-dna-link-between-north-european-and-west-african-dogs
#20
Adeniyi C Adeola, Sheila C Ommeh, Jiao-Jiao Song, S Charles Olaogun, Oscar J Sanke, Ting-Ting Yin, Guo-Dong Wang, Shi-Fang Wu, Zhong-Yin Zhou, Jacqueline K Lichoti, Bernard R Agwanda, Philip M Dawuda, Robert W Murphy, Min-Sheng Peng, Ya-Ping Zhang
Domestic dogs have an ancient origin and a long history in Africa. Nevertheless, the timing and sources of their introduction into Africa remain enigmatic. Herein, we analyse variation in mitochondrial DNA (mtDNA) D-loop sequences from 345 Nigerian and 37 Kenyan village dogs plus 1530 published sequences of dogs from other parts of Africa, Europe and West Asia. All Kenyan dogs can be assigned to one of three haplogroups (matrilines; clades): A, B, and C, while Nigerian dogs can be assigned to one of four haplogroups A, B, C, and D...
November 24, 2016: Journal of Genetics and Genomics, Yi Chuan Xue Bao
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