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https://www.readbyqxmd.com/read/28918583/evidence-for-contrasting-accumulation-pattern-of-cadmium-in-relation-to-other-elements-in-senilia-senilis-and-tagelus-adansoni-from-the-bijag%C3%A3-s-archipelago-guinea-bissau
#1
Teresa Catry, Paula Figueira, Lina Carvalho, Rui Monteiro, Pedro Coelho, Pedro Miguel Lourenço, Paulo Catry, Quintino Tchantchalam, Inês Catry, Maria J Botelho, Eduarda Pereira, José Pedro Granadeiro, Carlos Vale
Shellfish harvesting in intertidal areas is a widespread and economically important activity in many countries across West Africa. However, in some areas, there is virtually no information concerning the levels of contaminants (and other elements related to nutritional aspects) in the harvested species. We collected sediments and several individuals of the West African bloody cockle Senilia senilis and of the razor clam Tagelus adansoni during the dry season of 2015 nearby three islands in the Bijagós archipelago, Guinea-Bissau...
September 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28918539/accelerating-vaccine-development-during-the-2013-2016-west-african-ebola-virus-disease-outbreak
#2
Elizabeth S Higgs, Sheri A Dubey, Beth A G Coller, Jakub K Simon, Laura Bollinger, Robert A Sorenson, Barthalomew Wilson, Martha C Nason, Lisa E Hensley
The Ebola virus disease outbreak that began in Western Africa in December 2013 was unprecedented in both scope and spread, and the global response was slower and less coherent than was optimal given the scale and pace of the epidemic. Past experience with limited localized outbreaks, lack of licensed medical countermeasures, reluctance by first responders to direct scarce resources to clinical research, community resistance to outside interventions, and lack of local infrastructure were among the factors delaying clinical research during the outbreak...
September 17, 2017: Current Topics in Microbiology and Immunology
https://www.readbyqxmd.com/read/28917550/antidiabetic-potential-of-methanolic-and-flavonoid-rich-leaf-extracts-of-synsepalum-dulcificum-in-type-2-diabetic-rats
#3
Olabisi T Obafemi, Clement A Akinmoladun, Tolulope M Olaleye, Stephen O Agboade, Amos A Onasanya
BACKGROUND: Synsepalum dulcificum is a plant indigenous to West Africa. The fruit is used to modify taste of foods to sweetness. OBJECTIVES: This study aims to investigate the antidiabetic potentials of both methanolic and flavonoid-rich leaf extracts of S. dulcificum (MSD and FSD respectively) in type 2 diabetic Wistar albino rats. MATERIALS AND METHODS: Sixty three rats were randomly distributed into nine groups of seven animals each with group 1 serving as the normal control...
September 13, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28912754/the-gambian-bone-and-muscle-ageing-study-baseline-data-from-a-prospective-observational-african-sub-saharan-study
#4
Ayse Zengin, Anthony J Fulford, Yankuba Sawo, Landing M Jarjou, Inez Schoenmakers, Gail Goldberg, Ann Prentice, Kate A Ward
The Gambian Bone and Muscle Ageing Study is a prospective observational study investigating bone and muscle ageing in men and women from a poor, subsistence farming community of The Gambia, West Africa. Musculoskeletal diseases, including osteoporosis and sarcopenia, form a major part of the current global non-communicable disease burden. By 2050, the vast majority of the world's ageing population will live in low- and middle-income countries with an estimated two-fold rise in osteoporotic fracture. The study design was to characterise change in bone and muscle outcomes and to identify possible preventative strategies for fracture and sarcopenia in the increasing ageing population...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28911765/prevalence-of-hepatitis-d-virus-infection-in-sub-saharan-africa-a-systematic-review-and-meta-analysis
#5
Alexander J Stockdale, Mas Chaponda, Apostolos Beloukas, Richard Odame Phillips, Philippa C Matthews, Athanasios Papadimitropoulos, Simon King, Laura Bonnett, Anna Maria Geretti
BACKGROUND: Hepatitis D virus (also known as hepatitis delta virus) can establish a persistent infection in people with chronic hepatitis B, leading to accelerated progression of liver disease. In sub-Saharan Africa, where HBsAg prevalence is higher than 8%, hepatitis D virus might represent an important additive cause of chronic liver disease. We aimed to establish the prevalence of hepatitis D virus among HBsAg-positive populations in sub-Saharan Africa. METHODS: We systematically reviewed studies of hepatitis D virus prevalence among HBsAg-positive populations in sub-Saharan Africa...
October 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28911324/leadership-and-governance-of-community-health-worker-programmes-at-scale-a-cross-case-analysis-of-provincial-implementation-in-south-africa
#6
Helen Schneider, Nonhlanhla Nxumalo
BACKGROUND: National community health worker (CHW) programmes are returning to favour as an integral part of primary health care systems, often on the back of pre-existing community based initiatives. There are significant challenges to the integration and support of such programmes, and they require coordination and stewardship at all levels of the health system. This paper explores the leadership and governance tasks of large-scale CHW programmes at sub-national level, through the case of national reforms to South Africa's community based sector, referred to as the Ward Based Outreach Team (WBOT) strategy...
September 15, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28906052/forest-biomass-productivity-and-carbon-cycling-along-a-rainfall-gradient-in-west-africa
#7
Sam Moore, Stephen Adu-Bredu, Akwasi Duah-Gyamfi, Shalom D Addo-Danso, Forzia Ibrahim, Armel T Mbou, Agnès de Grandcourt, Riccardo Valentini, Giacomo Nicolini, Gloria Djagbletey, Kennedy Owusu-Afriyie, Agne Gvozdevaite, Imma Oliveras, Maria C Ruiz-Jaen, Yadvinder Malhi
Net primary productivity (NPP) is one of the most important parameters in describing the functioning of any ecosystem and yet it arguably remains a poorly quantified and understood component of carbon cycling in tropical forests, especially outside of the Americas. We provide the first comprehensive analysis of NPP and its carbon allocation to woody, canopy and root growth components at contrasting lowland West African forests spanning a rainfall gradient. Using a standardised methodology to study evergreen (EF), semi-deciduous (SDF), dry forests (DF) and woody savanna (WS), we find that (i) climate is more closely related with above and belowground C stocks than with NPP (ii) total NPP is highest in the SDF site, then the EF followed by the DF and WS and that (iii) different forest types have distinct carbon allocation patterns whereby SDF allocate in excess of 50% to canopy production and the DF and WS sites allocate 40-50% to woody production...
September 14, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28905131/exploring-evidence-of-positive-selection-signatures-in-cattle-breeds-selected-for-different-traits
#8
Mengistie Taye, Wonseok Lee, Soomin Jeon, Joon Yoon, Tadelle Dessie, Olivier Hanotte, Okeyo Ally Mwai, Stephen Kemp, Seoae Cho, Sung Jong Oh, Hak-Kyo Lee, Heebal Kim
Since domestication, the genome landscape of cattle has been changing due to natural and artificial selection forces resulting in several general and specialized cattle breeds of the world. Identifying genomic regions affected due to these forces in livestock gives an insight into the history of selection for economically important traits and genetic adaptation to specific environments of the populations under consideration. This study explores the genes/genomic regions under selection in relation to the phenotypes of Holstein, Hanwoo, and N'Dama cattle breeds using Tajima's D, XP-CLR, and XP-EHH population statistical methods...
September 13, 2017: Mammalian Genome: Official Journal of the International Mammalian Genome Society
https://www.readbyqxmd.com/read/28893277/development-of-an-hiv-vaccine-using-a-vesicular-stomatitis-virus-vector-expressing-designer-hiv-1-envelope-glycoproteins-to-enhance-humoral-responses
#9
REVIEW
Trina Racine, Gary P Kobinger, Eric J Arts
Vesicular stomatitis virus (VSV), like many other Rhabdoviruses, have become the focus of intense research over the past couple of decades based on their suitability as vaccine vectors, transient gene delivery systems, and as oncolytic viruses for cancer therapy. VSV as a vaccine vector platform has multiple advantages over more traditional viral vectors including low level, non-pathogenic replication in diverse cell types, ability to induce both humoral and cell-mediate immune responses, and the remarkable expression of foreign proteins cloned into multiple intergenic sites in the VSV genome...
September 12, 2017: AIDS Research and Therapy
https://www.readbyqxmd.com/read/28893071/a-model-of-collaboration-for-the-implementation-of-problem-based-learning-in-nursing-education-in-south-africa
#10
Mahlasela A Rakhudu, Mashudu Davhana-Maselesele, Ushonatefe Useh
BACKGROUND: The idea of collaboration between key stakeholders in nursing education for the implementation of problem-based learning (PBL) may have far-reaching implications for the institutions and students. MAIN OBJECTIVE: To develop a model of collaboration to facilitate the implementation of PBL in nursing education. METHODOLOGY: An exploratory sequential design was used. Qualitative data were collected from purposively recruited nurse educators from three universities in South Africa offering PBL and nurse managers from all the three hospitals in North West Province where PBL students are placed for clinical learning...
August 28, 2017: Curationis
https://www.readbyqxmd.com/read/28892490/development-of-risk-reduction-behavioral-counseling-for-ebola-virus-disease-survivors-enrolled-in-the-sierra-leone-ebola-virus-persistence-study-2015-2016
#11
Neetu Abad, Tasneem Malik, Archchun Ariyarajah, Patricia Ongpin, Matthew Hogben, Suzanna L R McDonald, Jaclyn Marrinan, Thomas Massaquoi, Anna Thorson, Elizabeth Ervin, Kyle Bernstein, Christine Ross, William J Liu, Karen Kroeger, Kara N Durski, Nathalie Broutet, Barbara Knust, Gibrilla F Deen
BACKGROUND: During the 2014-2016 West Africa Ebola Virus Disease (EVD) epidemic, the public health community had concerns that sexual transmission of the Ebola virus (EBOV) from EVD survivors was a risk, due to EBOV persistence in body fluids of EVD survivors, particularly semen. The Sierra Leone Ebola Virus Persistence Study was initiated to investigate this risk by assessing EBOV persistence in numerous body fluids of EVD survivors and providing risk reduction counseling based on test results for semen, vaginal fluid, menstrual blood, urine, rectal fluid, sweat, tears, saliva, and breast milk...
September 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28890666/discovering-drugs-for-the-treatment-of-ebola-virus
#12
REVIEW
Sandra L Bixler, Allen J Duplantier, Sina Bavari
PURPOSE OF REVIEW: Ebola virus, a member of the Filoviridae family, is a causative agent of severe viral hemorrhagic fever in humans. Over the past 40 years, the virus has been linked to several high mortality outbreaks in Africa with the recent West African outbreak resulting in over 11,000 deaths. This review provides a summary of the status of the drug discovery and development process for therapeutics for Ebola virus disease, with a focus on the strategies being used and the challenges facing each stage of the process...
2017: Current Treatment Options in Infectious Diseases
https://www.readbyqxmd.com/read/28890126/the-nebulous-ecology-of-native-invasions
#13
REVIEW
Lloyd L Nackley, Adam G West, Andrew L Skowno, William J Bond
In the Anthropocene, alien species are no longer the only category of biological organism establishing and rapidly spreading beyond historical boundaries. We review evidence showing that invasions by native species are a global phenomenon and present case studies from Southern Africa, and elsewhere, that reveal how climate-mediated expansions of native plants into adjacent communities can emulate the functional and structural changes associated with invasions by alien plant species. We conclude that integrating native invasions into ecological practice and theory will improve mechanistic models and better inform policy and adaptive ecological management in the 21st century...
September 7, 2017: Trends in Ecology & Evolution
https://www.readbyqxmd.com/read/28890096/-the-choice-of-a-child-s-first-name-in-west-africa
#14
Hawa Camara, Alice Titia Rizzi
Choosing a name is a powerful act, filled with meaning. In most societies, this act is accompanied by specific rites and rituals. By naming a child, we are acknowledging their existence. A transmission is thereby created between the person giving the name and the person who will bear it. The naming of children in West Africa, particularly among the Soninke people, constitutes an example of the elements which come into play when a child is given a name.
September 2017: Soins. Pédiatrie, Puériculture
https://www.readbyqxmd.com/read/28887701/morphological-and-molecular-identification-of-rhipicephalus-boophilus-microplus-in-nigeria-west-africa-a-threat-to-livestock-health
#15
J Kamani, D A Apanaskevich, R Gutiérrez, Y Nachum-Biala, G Baneth, S Harrus
The cattle tick Rhipicephalus (Boophilus) microplus was first reported in West Africa in Ivory Coast, in 2007. Since then it has made an aggressive eastward advancement having been reported in four other West African countries: Mali, Burkina Faso, Togo and Benin. We herein report the first molecular identification of this tick species in Nigeria, West Africa, and highlight the threat it poses to livestock health. A nation-wide tick survey was conducted in 12 out of 36 states across the various agro ecological zones of Nigeria over a 1 year period (April 2014-March 2015)...
September 8, 2017: Experimental & Applied Acarology
https://www.readbyqxmd.com/read/28884289/dispersals-of-the-siberian-y-chromosome-haplogroup-q-in-eurasia
#16
Yun-Zhi Huang, Horolma Pamjav, Pavel Flegontov, Vlastimil Stenzl, Shao-Qing Wen, Xin-Zhu Tong, Chuan-Chao Wang, Ling-Xiang Wang, Lan-Hai Wei, Jing-Yi Gao, Li Jin, Hui Li
The human Y-chromosome has proven to be a powerful tool for tracing the paternal history of human populations and genealogical ancestors. The human Y-chromosome haplogroup Q is the most frequent haplogroup in the Americas. Previous studies have traced the origin of haplogroup Q to the region around Central Asia and Southern Siberia. Although the diversity of haplogroup Q in the Americas has been studied in detail, investigations on the diffusion of haplogroup Q in Eurasia and Africa are still limited. In this study, we collected 39 samples from China and Russia, investigated 432 samples from previous studies of haplogroup Q, and analyzed the single nucleotide polymorphism (SNP) subclades Q1a1a1-M120, Q1a2a1-L54, Q1a1b-M25, Q1a2-M346, Q1a2a1a2-L804, Q1a2b2-F1161, Q1b1a-M378, and Q1b1a1-L245...
September 7, 2017: Molecular Genetics and Genomics: MGG
https://www.readbyqxmd.com/read/28880905/population-genetics-of-southern-hemisphere-tope-shark-galeorhinus-galeus-intercontinental-divergence-and-constrained-gene-flow-at-different-geographical-scales
#17
Aletta E Bester-van der Merwe, Daphne Bitalo, Juan M Cuevas, Jennifer Ovenden, Sebastián Hernández, Charlene da Silva, Meaghen McCord, Rouvay Roodt-Wilding
The tope shark (Galeorhinus galeus Linnaeus, 1758) is a temperate, coastal hound shark found in the Atlantic and Indo-Pacific oceans. In this study, the population structure of Galeorhinus galeus was determined across the entire Southern Hemisphere, where the species is heavily targeted by commercial fisheries, as well as locally, along the South African coastline. Analysis was conducted on a total of 185 samples using 19 microsatellite markers and a 671 bp fragment of the NADH dehydrogenase subunit 2 (ND2) gene...
2017: PloS One
https://www.readbyqxmd.com/read/28879827/the-prevalence-and-factors-associated-with-stunting-among-infants-aged-6-months-in-a-peri-urban-south-african-community
#18
Tonderayi M Matsungo, Herculina S Kruger, Mieke Faber, Marinel Rothman, Cornelius M Smuts
OBJECTIVE: To determine the prevalence and factors associated with stunting in 6-month-old South African infants. DESIGN: This cross-sectional study was part of the baseline of a randomized controlled trial. Weight-for-length, length-for-age and weight-for-age Z-scores were based on the WHO classification. Blood samples were analysed for Hb, plasma ferritin and soluble transferrin receptor (sTfR). Socio-economic, breast-feeding and complementary feeding practices were assessed by questionnaire...
September 7, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28879152/national-laboratory-policies-and-plans-in-sub-saharan-african-countries-gaps-and-opportunities
#19
Pascale Ondoa, Ankie van der Broek, Christel Jansen, Hilde de Bruijn, Constance Schultsz
BACKGROUND: The 2008 Maputo Declaration calls for the development of dedicated national laboratory policies and strategic plans supporting the enhancement of laboratory services in response to the long-lasting relegation of medical laboratory systems in sub-Saharan Africa. OBJECTIVES: This study describes the extent to which laboratories are addressed in the national health policies and plans created directly following the 2008 momentum for laboratory strengthening...
2017: African Journal of Laboratory Medicine
https://www.readbyqxmd.com/read/28878251/effects-of-biochar-waste-water-irrigation-and-fertilization-on-soil-properties-in-west-african-urban-agriculture
#20
Volker Häring, Delphine Manka'abusi, Edmund K Akoto-Danso, Steffen Werner, Kofi Atiah, Christoph Steiner, Désiré J P Lompo, Samuel Adiku, Andreas Buerkert, Bernd Marschner
In large areas of sub-Saharan Africa crop production must cope with low soil fertility. To increase soil fertility, the application of biochar (charred biomass) has been suggested. In urban areas, untreated waste water is widely used for irrigation because it is a nutrient-rich year-round water source. Uncertainty exists regarding the interactions between soil properties, biochar, waste water and fertilization over time. The aims of this study were to determine these interactions in two typical sandy, soil organic carbon (SOC) and nutrient depleted soils under urban vegetable production in Tamale (Ghana) and Ouagadougou (Burkina Faso) over two years...
September 6, 2017: Scientific Reports
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