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Exhaled nitric oxide

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https://www.readbyqxmd.com/read/28636794/differences-and-similarities-between-bronchopulmonary-dysplasia-and-asthma-in-schoolchildren
#1
Björn Nordlund, Anna James, Christina Ebersjö, Gunilla Hedlin, Eva B Broström
BACKGROUND: The long-term respiratory characteristics of ex-preterm children with bronchopulmonary dysplasia (BPD) are not established. The objective of this study was to describe hallmarks of BPD at school age in comparison to children with atopic asthma. METHODS: This study was a cross-sectional descriptive comparative study in a hospital-based setting. Thirty schoolchildren diagnosed with BPD (10.4 years/born at 26.6 weeks' gestation) and 30 age- and sex-matched children with asthma and sensitized to airborne allergens (IgE >0...
June 21, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28635619/on-the-importance-of-accurate-quantification-of-individual-volatile-metabolites-in-exhaled-breath
#2
David Smith, Patrik Spanel
It is argued that shortcomings of certain approaches to breath analysis research based on superficial interpretation of non-quantitative data are inadvertently inhibiting the progression of non-invasive breath analysis into clinical practice. The objective of this perspective is to suggest more clinically profitable approaches to breath research. Thus, following a discourse on the challenges and expectations in breath research, a brief indication is given of the analytical techniques currently used for the analysis of very humid exhaled breath...
June 21, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28628045/cardio-respiratory-effects-of-air-pollution-in-a-panel-study-of-outdoor-physical-activity-and-health-in-rural-older-adults
#3
David M Stieb, Robin Shutt, Lisa Kauri, Sarah Mason, Li Chen, Mieczyslaw Szyszkowicz, Nina A Dobbin, Marc Rigden, Branka Jovic, Marie Mulholland, Martin S Green, Ling Liu, Guillaume Pelletier, Scott A Weichenthal, Robert E Dales, Isaac Luginaah
OBJECTIVE: To examine cardio-respiratory effects of air pollution in rural older adults exercising outdoors. METHODS: Adults 55 and over completed measurements of blood pressure, peak expiratory flow and oximetry daily, and of heart rate variability, endothelial function, spirometry, fraction of exhaled nitric oxide and urinary oxidative stress markers weekly, before and after outdoor exercise, for 10 weeks. Data were analyzed using linear mixed effect models. RESULTS: Pooled estimates combining 2013 (n = 36 participants) and 2014 (n = 41) indicated that an interquartile increase in the air quality health index (AQHI) was associated with a significant (P < 0...
April 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28612760/effects-of-growth-and-aging-on-the-reference-values-of-pulmonary-nitric-oxide-dynamics-in-healthy-subjects
#4
Marieann Högman, Alexandra Thornadtsson, Per Liv, Thong Hua-Huy, Anh-Tuan Dinh-Xuan, Ellen Tufvesson, Holger Dressel, Christer Janson, Kirsi Koskela, Panu Oksa, Riitta Sauni, Jukka Uitti, Eeva Moilanen, Lauri Lehtimäki
The lung just like all other organs is affected by age. The lung matures by the age of 20 and age related changes starts around middle age, 40-50 years. Exhaled nitric oxide (F<sub></sub>E<sub></sub>NO) has been shown to be age, height and gender dependent. We hypothesize that the nitric oxide (NO) parameters alveolar NO (C<sub>A</sub>NO), airway flux (J<sub>aw</sub>NO), airway diffusing capacity (D<sub>aw</sub>NO) and airway wall content (C<sub>aw</sub>NO), will also demonstrate this dependence...
June 14, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28606216/comparable-reductions-in-hyperpnoea-induced-bronchoconstriction-and-markers-of-airway-inflammation-after-supplementation-with-6%C3%A2-2-and-3%C3%A2-1-g-d-of-long-chain-n-3-pufa-in-adults-with-asthma
#5
Neil C Williams, Kirsty A Hunter, Dominick E Shaw, Kim G Jackson, Graham R Sharpe, Michael A Johnson
Although high dose n-3 PUFA supplementation reduces exercise- and hyperpnoea-induced bronchoconstriction (EIB/HIB), there are concurrent issues with cost, compliance and gastrointestinal discomfort. It is thus pertinent to establish the efficacy of lower n-3 PUFA doses. Eight male adults with asthma and HIB and eight controls without asthma were randomly supplemented with two n-3 PUFA doses (6·2 g/d (3·7 g EPA and 2·5 g DHA) and 3·1 g/d (1·8 g EPA and 1·3 g DHA)) and a placebo, each for 21 d followed by 14 d washout...
June 13, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28592098/-the-effect-of-short-term-exposure-to-ambient-no-2-on-lung-function-and-fractional-exhaled-nitric-oxide-in-33-chronic-obstructive-pulmonary-disease-patients
#6
J Shan, Y Ni, W Dong, J H Xu, L Pan, H Y Li, X Yang, S W Wu, Y H Chen, F R Deng, X B Guo
Objectives: To investigate the effect of short-term exposure to ambient NO(2) has influence on lung function and fractional exhaled nitric oxide (FeNO) in chronic obstructive pulmonary disease (COPD) patients. Methods: A panel of doctor-diagnosed stable COPD patients (n=33) were recruited and repeatedly measured for lung function and FeNO from December 2013 to October 2014. The patients who lived in Beijing for more than one year and aged between 60 and 85 years old were included in the study. We excluded patients with asthma, bronchial tensor, lung cancer and other respiratory disorders other than chronic obstructive pulmonary disease and occupational exposure and chest trauma surgery patients...
June 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28588900/associations-between-serum-25-oh-d-concentrations-and-prevalent-asthma-among-children-living-in-communities-with-differing-levels-of-urbanization-a-cross-sectional-study
#7
Suzanne L Pollard, John J Lima, Karina Romero, Carla Tarazona-Meza, Edward Mougey, Katherine Tomaino, Gary Malpartida-Guzmán, Nadia N Hansel, William Checkley
BACKGROUND: Prior evidence suggests that vitamin D deficiency may increase the risk of asthma and atopy and impair pulmonary function in children. METHODS: In this cross-sectional analysis nested in a case-control study, we analyzed serum 25(OH)D concentrations in 413 children with asthma and 471 children without asthma living in two geographically adjacent study communities (Pampas and Villa El Salvador). We measured total and antigen-specific IgE levels, pulmonary function, asthma control, and exhaled nitric oxide...
2017: Asthma research and practice
https://www.readbyqxmd.com/read/28588744/effect-of-personal-exposure-to-black-carbon-on-changes-in-allergic-asthma-gene-methylation-measured-5%C3%A2-days-later-in-urban-children-importance-of-allergic-sensitization
#8
Kyung Hwa Jung, Stephanie Lovinsky-Desir, Beizhan Yan, David Torrone, Jennifer Lawrence, Jacqueline R Jezioro, Matthew Perzanowski, Frederica P Perera, Steven N Chillrud, Rachel L Miller
BACKGROUND: Asthma gene DNA methylation may underlie the effects of air pollution on airway inflammation. However, the temporality and individual susceptibility to environmental epigenetic regulation of asthma has not been fully elucidated. Our objective was to determine the timeline of black carbon (BC) exposure, measured by personal sampling, on DNA methylation of allergic asthma genes 5 days later to capture usual weather variations and differences related to changes in behavior and activities...
2017: Clinical Epigenetics
https://www.readbyqxmd.com/read/28587037/exhaled-nitric-oxide-breath-analysis-used-for-predicting-development-of-lung-injury-after-chest-radiation-therapy
#9
D Nader
No abstract text is available yet for this article.
May 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28584938/the-effect-of-sleep-duration-on-exhaled-nitric-oxide-levels-in-u-s-adults
#10
Jensen H Hyde, Rehan Qayyum
PURPOSE: Poor sleep quality and duration are associated with systemic endothelial dysfunction. However, an association between poor sleep and pulmonary endothelial dysfunction has not been elucidated. We sought to determine if there is a relationship between sleep duration and fractional exhaled nitric oxide (FeNO) concentrations as a surrogate for pulmonary endothelial function. METHODS: We used three National Health and Nutrition Examination Survey (NHANES) cycles (2007-2012)...
June 6, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28579561/normal-values-of-offline-exhaled-and-nasal-nitric-oxide-in-healthy-children-and-teens-using-chemiluminescence
#11
Awen Menou, Diane Babeanu, Henry-Nicolas Paruit, Aline Ordureau, Sophie Guillard, Arnaud Christian Chambellan
Nitric oxide (NO) can be used to detect respiratory or ciliary diseases. Fractional exhaled nitric oxide (FeNO) measurement can reflect ongoing eosinophilic airway inflammation and has a diagnostic utility as a test for asthma screening and follow-up while nasal nitric oxide (nNO) is a valuable screening tool for the diagnosis of Primary Ciliary Dyskinesia (PCD). The possibility to collect airway gas samples in an offline manner offers the advantage to extend these measures and improve the screening and management of these diseases, but normal values from healthy children and teens remain sparse...
June 5, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28577109/phosgene-induced-acute-lung-injury-ali-differences-from-chlorine-induced-ali-and-attempts-to-translate-toxicology-to-clinical-medicine
#12
REVIEW
Wenli Li, Juergen Pauluhn
BACKGROUND: Phosgene (carbonyl dichloride) gas is an indispensable chemical inter-mediate used in numerous industrial processes. There is no clear consensus as to its time- and inhaled-dose-dependent etiopathologies and associated preventive or therapeutic treatment strategies. METHODS: Cardiopulmonary function was examined in rats exposed by inhalation to the alveolar irritant phosgene or to the airway irritant chlorine during and following exposure. Terminal measurements focused on hematology, protein extravasation in bronchoalveolar lavage (BAL), and increased lung weight...
December 2017: Clinical and Translational Medicine
https://www.readbyqxmd.com/read/28552381/influence-of-maternal-body-mass-index-and-macrophage-activation-on-asthma-exacerbations-in-pregnancy
#13
Vanessa E Murphy, Megan E Jensen, Heather Powell, Peter G Gibson
BACKGROUND: Obesity is a risk factor for exacerbations of asthma, but the mechanisms of this effect in pregnancy are unknown. OBJECTIVE: This study determined the influence of maternal body mass index, gestational weight gain, eosinophilic inflammation, and systemic macrophage activation on the risk of exacerbations during pregnancy. METHODS: Women with asthma (n = 164) participated in the study. Body mass index recorded at baseline (17 weeks gestation) was categorized as healthy weight (18...
May 25, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28544706/exhaled-nitric-oxide-pulmonary-function-and-disease-activity-in-children-with-systemic-lupus-erythematosus
#14
Jitladda Deerojanawong, Pitchaya Leartphichalak, Ankanee Chanakul, Suchada Sritippayawan, Rujipat Samransamruajkit
AIM: To determine the association among fractional exhaled nitric oxide (FENO), pulmonary function, and disease activity in children with systemic lupus erythematosus (SLE). METHODS: Children aged 7-18 years, diagnosed with SLE under the criteria of the American Rheumatism Association (revised 2012), were enrolled. All eligible participants had disease activity, FENO, and pulmonary function evaluated and re-evaluated at 6-month follow-up. RESULTS: Twenty-four children (95...
May 22, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28527680/sensitivity-of-salivary-hydrogen-sulfide-to-psychological-stress-and-its-association-with-exhaled-nitric-oxide-and-affect
#15
Juliet L Kroll, Chelsey A Werchan, Audrey G Reeves, Kevin J Bruemmer, Alexander R Lippert, Thomas Ritz
BACKGROUND: Hydrogen sulfide (H2S) is the third gasotransmitter recently discovered after nitric oxide (NO) and carbon monoxide. Both NO and H2S are involved in multiple physiological functions. Whereas NO has been shown to vary with psychological stress, the influence of stress on H2S and the relationship between H2S and NO are unknown. We therefore examined levels of salivary H2S and NO in response to a stressful final academic exam period. METHODS: Measurements of stress, negative affect, and fraction of exhaled NO (FENO), were obtained from students (N=16) and saliva was collected at three time points: low-stress period in the semester, early exam period, and late exam period...
May 18, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28524604/prevalence-of-high-fractional-exhaled-nitric-oxide-among-us-youth-with-asthma
#16
Duong T Nguyen, Brian K Kit, Debra Brody, Lara J Akinbami
BACKGROUND: High fractional exhaled nitric oxide (FeNO) is an indicator of poor asthma control and has been proposed as a non-invasive assessment tool to guide asthma management. OBJECTIVE: We aimed to describe the prevalence of and factors associated with high FeNO among US youth with asthma. METHODS: Data from 716 children and adolescents with asthma ages 6-19 years who participated in the 2007-2012 National Health and Nutrition Examination Survey were analyzed...
June 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28515402/differences-in-fraction-of-exhaled-nitric-oxide-values-measured-by-two-hand-helded-analyzers-nobreath-%C3%A2-and-niox-vero-%C3%A2
#17
Takahiro Tsuburai, Yousuke Kamide, Yuto Nakamura, Yasuhiro Tomita, Yuto Hamada, Kentaro Watai, Hiroaki Hayashi, Kiyoshi Sekiya, Chihiro Mitsui, Yuma Fukutomi, Akio Mori, Masami Taniguchi
BACKGROUND: The fraction of exhaled nitric oxide (FENO) is a useful marker of asthma control. The FENO measurement with two hand-helded analyzers (NObreath(®) and NIOX Vero(®)) may be more affordable, no studies have examined the differences in FENO values measured with those methods in adult. METHODS: The study population comprised 44 subjects at our outpatient clinic. FeNO values (FENOb and FENOv) were measured by two methods (NObreath(®) and NIOX Vero(®))...
2017: Arerugī, [Allergy]
https://www.readbyqxmd.com/read/28513250/combined-measurements-of-fractional-exhaled-nitric-oxide-and-nasal-nitric-oxide-levels-for-assessing-upper-airway-diseases-in-asthmatic-patients
#18
Takamitsu Asano, Masaya Takemura, Yoshihiro Kanemitsu, Makoto Yokota, Kensuke Fukumitsu, Norihisa Takeda, Hiroya Ichikawa, Hisatoshi Hijikata, Takehiro Uemura, Osamu Takakuwa, Hirotsugu Ohkubo, Ken Maeno, Yutaka Ito, Tetsuya Oguri, Atsushi Nakamura, Yumi Maki, Yoshihisa Nakamura, Motohiko Suzuki, Akio Niimi
BACKGROUND: Despite the close linkage between rhinitis, chronic rhinosinusitis (CRS) and asthma, relevant biomarkers of both upper and lower airway inflammation are rare. METHODS: Patients with asthma (without upper airway disease [UAD; n = 24], with rhinitis [n = 25], CRS [n = 24], and nasal polyps [n = 2]), isolated rhinitis (n = 13), isolated CRS (n = 13), and 10 healthy controls were prospectively recruited. Fractional exhaled nitric oxide (NO) levels at 50 mL/s (FeNO50), nasal NO levels, Lund-Macay-scores of sinus computed tomography and an asthma control questionnaire (ACQ) were evaluated...
May 17, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28497918/allergic-rhinitis-in-preschool-children-and-the-clinical-utility-of-feno
#19
Jisun Yoon, Yean Jung Choi, Eun Lee, Hyun Ju Cho, Song I Yang, Young Ho Kim, Young Ho Jung, Ju Hee Seo, Ji Won Kwon, Hyo Bin Kim, So Yeon Lee, Bong Seong Kim, Jung Yeon Shim, Eun Jin Kim, Joo Shil Lee, Soo Jong Hong
PURPOSE: The nature of allergic rhinitis (AR) in preschool aged children remains incompletely characterized. This study aimed to investigate the prevalence of AR and its associated risk factors in preschool-aged children and to assess the clinical utility of fractional exhaled nitric oxide (FeNO). METHODS: This general population-based, cross-sectional survey included 933 preschool-aged (3- to 7-year-old) children from Korea. Current AR was defined as having nasal symptoms within the last 12 months and physician-diagnosed AR...
July 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28491110/tai-chi-chuan-exercise-improves-pulmonary-function-and-decreases-exhaled-nitric-oxide-level-in-both-asthmatic-and-nonasthmatic-children-and-improves-quality-of-life-in-children-with-asthma
#20
Hsin-Chia Lin, Hao-Pai Lin, Hsin-Hui Yu, Li-Chieh Wang, Jyh-Hong Lee, Yu-Tsan Lin, Yao-Hsu Yang, Pei-Yi Li, Wei-Zen Sun, Bor-Luen Chiang
Tai-Chi-Chuan (TCC) is an exercise of low-to-moderate intensity which is suitable for asthmatic patients. The aim of our study is to investigate improvements of the lung function, airway inflammation, and quality of life of asthmatic children after TCC. Participants included sixty-one elementary school students and they were divided into asthmatic (n = 29) and nonasthmatic (n = 32) groups by the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. Among them, 20 asthmatic and 18 nonasthmatic children volunteered to participate in a 60-minute TCC exercise weekly for 12 weeks...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
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