keyword
https://read.qxmd.com/read/37667535/erythrocyte-transfusions-are-associated-with-retinopathy-of-prematurity-in-extremely-low-gestational-age-newborns
#21
JOURNAL ARTICLE
Kirsten Glaser, Christoph Härtel, Olaf Dammann, Egbert Herting, Oliver Andres, Christian P Speer, Wolfgang Göpel, Andreas Stahl
AIM: Retinopathy of prematurity (ROP) is a major morbidity in preterm infants causing visual impairment including blindness. Prevention and timely treatment are critical. We investigated the potential role of red blood cell (RBC) transfusions as risk factor for ROP development. METHODS: Retrospective cohort study of data from 68 tertiary level neonatal intensive care units in Germany. Preterm infants born at 22 + 0 to 28 + 6 weeks of gestation between January 2009 and December 2021 were enrolled...
September 4, 2023: Acta Paediatrica
https://read.qxmd.com/read/37663108/sub-acute-combined-degeneration-of-the-spinal-cord-as-first-presentation-of-coeliac-disease-in-a-sudanese-child
#22
Omer S M Suliman
The prevalence of coeliac disease (CD) is rapidly rising in both developed and underdeveloped countries. CD classically presents with gastrointestinal manifestations, but it is now increasingly considered as a multisystem disease mostly affecting the central nervous system. Recently, a non-biopsy approach for the diagnosis of CD has been recommended by the European Society for paediatric gastroentrology, hepatology and nutrition. Here, we are reporting a 12-year-old Sudanese boy who presented with chronic diarrhoea and weight loss and lower limbs weakness...
2023: Sudanese Journal of Paediatrics
https://read.qxmd.com/read/37663095/nutritional-status-and-dietary-habits-among-quranic-school-s-khalwa-students-in-khartoum-state-sudan-a-cross-sectional-study
#23
JOURNAL ARTICLE
Ahmed Abdulgadir Noureddin, Abubaker Emadeldin A Koko, Mohammed A Adam, Almegdad Sharafaldin M Ahmed, Ahmed Abdallah A Mahmoud, Mohammed Almojtaba Abdalhameed, Mohammed Elkhalifa, Anoud Omer
Khalawi are non-governmental, traditional educational boarding institutions, widely scattered in Sudan. Many Khalawi are resource-limited with deficient feeding and poor housing conditions, which could seriously affect the students' health. A cross-sectional study was conducted, involving all students of a Khalwa in Sharg Al-Neel Locality, Khartoum State. Demographic data were collected using a structured questionnaire with anthropometric measurements, along with laboratory and clinical assessments for anaemia...
2023: Sudanese Journal of Paediatrics
https://read.qxmd.com/read/37649102/gdf-15-and-hepcidin-as-a-therapeutic-target-for-anemia-in-chronic-kidney-disease
#24
JOURNAL ARTICLE
Naglaa Makram Farag, Mahmoud Mousa, Eman Elsayed, Ahlam Ismeil
BACKGROUND: Anaemia is a common presenting feature among patients with chronic kidney disease (CKD) and associated with poor clinical outcomes. We evaluated the diagnostic validity of growth differentiation factor-15 (GDF-15) and hepcidin as it is not clear if they are useful as a biomarkers of anaemia among non-dialysis CKD egyptian patients. METHOD: An analytical cross-sectional study was conducted among non-dialysis CKD patients (n = 60) and apparently healthy controls (n = 28) at Minia University maternity & children Hospital...
August 30, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37637580/correlation-of-iron-status-and-micronutrients-with-anaemia-of-childhood-haematopoietic-malignancies-a-study-from-northern-india
#25
JOURNAL ARTICLE
Archana Tripathi, Monika Singh, Mamta Jaiswal, Dezy Singh, Arvind Kumar, Deepa Hatwal
BACKGROUND: Most cancer patients undergoing chemotherapy develop anemia during their course of treatment. There is a need for early treatment for chemotherapy-induced anemia to prevent morbidity and mortality. MATERIAL AND METHOD: This is a hospital-based study, conducted over one year and included 59 children who are known cases of hematological malignancy aged up to 18 years. Standard methods were used to measure micronutrients and complete blood count. Statistical analysis was done using SPSS for Windows, Version 15...
July 2023: Curēus
https://read.qxmd.com/read/37628359/brain-volumes-and-cognition-in-patients-with-sickle-cell-anaemia-a-systematic-review-and-meta-analysis
#26
REVIEW
Shifa Hamdule, Fenella J Kirkham
Cognitive decline is a major problem in paediatric and adult patients with sickle cell anaemia (SCA) and affects the quality of life. Multiple studies investigating the association between quantitative and qualitative neuroimaging findings and cognition have had mixed results. Hence, the aetiology of cognitive decline in this population is not clearly understood. Several studies have established cerebral atrophy in SCA children as well as adults, but the relationship between cognition and brain volumes remains unclear...
August 8, 2023: Children
https://read.qxmd.com/read/37593443/dyskeratosis-congenita-natural-history-of-the-disease-through-the-study-of-a-cohort-of-patients-diagnosed-in-childhood
#27
JOURNAL ARTICLE
M L Uria-Oficialdegui, S Navarro, L Murillo-Sanjuan, C Rodriguez-Vigil, M I Benitez-Carbante, C Blazquez-Goñi, J A Salinas, C Diaz-de-Heredia
BACKGROUND: Dyskeratosis congenita (DC) is a multisystem and ultra-rare hereditary disease characterized by somatic involvement, bone marrow failure, and predisposition to cancer. The main objective of this study is to describe the natural history of DC through a cohort of patients diagnosed in childhood and followed up for a long period of time. MATERIAL AND METHODS: Multicenter, retrospective, longitudinal study conducted in patients followed up to 24 years since being diagnosed in childhood (between 1998 and 2020)...
2023: Frontiers in Pediatrics
https://read.qxmd.com/read/37574257/paroxysmal-cold-hemoglobinuria-a-diagnostic-dilemma-in-a-paediatric-patient
#28
Keenan O Hogan, Gabor Oroszi
BACKGROUND: Autoimmune hemolytic anaemia is rare in the paediatric population. Differentiation of the underlying aetiology is complicated by heterogeneity in diagnostic criteria and testing strategies. Paroxysmal cold hemoglobinuria (PCH) is an uncommon form of paediatric autoimmune hemolytic anaemia. Identification of the causative biphasic hemolysin requires clinical recognition and access to the Donath-Landsteiner (DL) test. CASE PRESENTATION: We report a young paediatric patient with no significant past medical history who presented with severe anaemia, jaundice, and dark urine following a respiratory illness...
October 2023: Transfusion Medicine
https://read.qxmd.com/read/37565393/trial-related-blood-sampling-and-red-blood-cell-transfusions-in-preterm-infants
#29
JOURNAL ARTICLE
Anna Elisabet Lewis, Susanne S Kappel, Samya Hussain, Per T Sangild, Gitte Zachariassen, Lise Aunsholt
AIM: To determine if trial-related blood sampling increases the risk of later red blood cell (RBC) transfusion in very preterm infants, we compared the volume of clinical- and trial-related blood samples, in a specific trial and correlated to subsequent RBC transfusion. METHODS: For 193 very preterm infants, participating in the FortiColos trial (NCT03537365), trial-related blood volume drawn was in accordance with ethical considerations established by the European Commission...
August 11, 2023: Acta Paediatrica
https://read.qxmd.com/read/37534197/celiac-disease-in-paediatric-patients-in-the-united-arab-emirates-a-single-center-descriptive-study
#30
JOURNAL ARTICLE
Asma H AlNababteh, Christos Tzivinikos, Saif Al-Shamsi, Romona Devi Govender, Rami H Al-Rifai
INTRODUCTION: Celiac disease (CD) is an autoimmune disorder that is provoked by the consumption of gluten in genetically vulnerable individuals. CD affects individuals worldwide with an estimated prevalence of 1% and can manifest at any age. Growth retardation and anemia are common presentations in children with CD. The objective of this study is to estimate the prevalence of CD in multiple "at risk groups" and to characterize children with CD, presented to a tertiary hospital in Dubai, United Arab Emirates (UAE)...
2023: Frontiers in Pediatrics
https://read.qxmd.com/read/37525810/methemoglobinemia-secondary-to-a-traditional-healing-practice-using-mothballs-a-need-of-pediatric-vigilance
#31
Varun Anand, Dilip K Venkatesan, Pugazhenthan T, Md Naseem, Santosh K Rathia
Acute-onset unexplained hypoxemia persisting despite 100% oxygen has a limited differential diagnosis but poses a challenging diagnostic dilemma. Methemoglobinemia, a hemolytic condition, may lead to significant complications if it goes undiagnosed during the critical golden hour of an emergency department (ED) presentation. This case report presents the clinical details of a 30-month-old child with acute intravascular hemolysis evident by severe pallor and hemoglobinuria and severe hypoxia documented on pulse oximetry...
June 2023: Curēus
https://read.qxmd.com/read/37520059/treatment-of-immunoglobulin-resistant-kawasaki-disease-a-bayesian-network-meta-analysis-of-different-regimens
#32
REVIEW
Yan Pan, Qihong Fan, Luoyi Hu
BACKGROUND: This study aimed to gather evidence from clinical trials on the efficacy and safety of the available treatments for intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD) in children. METHODS: This work adopted the Newcastle-Ottawa scale to analyse the quality of the enrolled articles. A network meta-analysis was performed using clinical trials that compared drugs used to treat IVIG-resistant KD. Aggregate Data Drug Information System software v...
2023: Frontiers in Pediatrics
https://read.qxmd.com/read/37490683/takayasu-s-arteritis-as-an-incidental-finding-in-a-patient-with-celiac-disease-the-importance-of-positron-emission-computed-tomography
#33
JOURNAL ARTICLE
Amelia Moreno-Sánchez, David Molina-Herranz, Yurena Aguilar-de-la-Red, Lorenzo Jiménez-Montañés, Marta Medrano-SanIldefonso, Ruth García-Romero
BACKGROUND: Takayasu arteritis is a large-vessel vasculitis which affects large-caliber elastic arteries, primarily the aorta and its main branches. It mainly affects women between 20-30 years, so it is rare in children. CASE REPORT: We describe the case of a 15-year-old female who was followed up since she was 9 years old due to celiac disease. At the age of 13, anaemia of chronic disorders associated to elevated C-reactive protein and erythrocyte sedimentation were detected...
2023: Boletín Médico del Hospital Infantil de México
https://read.qxmd.com/read/37275082/etiology-and-complications-of-deep-neck-space-infections-a-hospital-based-retrospective-study
#34
JOURNAL ARTICLE
Carnegie Desa, Markandeya Tiwari, Sainath Pednekar, Siddhartha Basuroy, Aman Rajadhyaksha, Siddhi Savoiverekar
Infections of the deep spaces of the neck often present a true clinical challenge to a Head and Neck surgeon which may rapidly spread due to the various connections between the spaces resulting in morbidity and mortality. This study aims to obtain knowledge about various DNSI's and their predisposing factors.. It was a hospital based retrospective cross-sectional study done in Goa Medical College, India. A total of 300 patients who presented with DNSI's over the past 7 years were studied. Simple proportions and percentages were calculated and Chi-square test was used to study associations...
June 2023: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/37263765/tailing-growth-neonatal-jaundice-and-anaemia
#35
JOURNAL ARTICLE
Lucy Jefferson, Athimalaipet V Ramanan, Michelle Cummins, Marion Roderick
At medical school, there is a phrase to help us remember that common things are common: 'If you hear hooves think horses, not zebras'. However, zebras do exist, and from time to time in general paediatric and neonatal practice, we will encounter these rare diagnoses, more of which we can now accurately diagnose through the ever-expanding field of genomics. Our case demonstrates how a rare diagnosis can present with common features of growth restriction, jaundice and anaemia. Paediatricians therefore require a high index of suspicion and increasing knowledge of the logistics of genetic testing...
October 2023: Archives of Disease in Childhood. Education and Practice Edition
https://read.qxmd.com/read/37189982/identifying-the-aetiology-of-acute-liver-failure-is-crucial-to-impact-positively-on-outcome
#36
JOURNAL ARTICLE
Angelo Di Giorgio, Silvia Gamba, Naire Sansotta, Emanuele Nicastro, Michele Colledan, Lorenzo D'Antiga
Management of children with acute liver failure is challenging. In this retrospective study, paediatric patients diagnosed with ALF at our centre, in the last 26 years, were divided into two groups (G1 = diagnosed from 1997 to 2009; G2 = from 2010 to 2022) and compared to see whether they differed with regard to aetiologies, need for liver transplantation (LT), and outcome. A total of 90 children (median age 4.6 years, range 1.2-10.4; M/F = 43/47) were diagnosed with ALF, by autoimmune hepatitis (AIH) in 16 (18%), paracetamol overdose in 10 (11%), Wilson disease in 8 (9%), and other causes in 19 (21%); 37 (41%) had indeterminate ALF (ID-ALF)...
April 16, 2023: Children
https://read.qxmd.com/read/37184503/characterization-of-colonoscopies-in-preschool-children
#37
JOURNAL ARTICLE
Rishi Bolia, Nikhil Thapar, Geoffrey D Withers, Looi C Ee
OBJECTIVES: The indications, diagnostic yield, complications and cecal and ileal intubation rates (CIR and IIR) for colonoscopies in children aged < 6 years, denoted pre-schoolers, is unclear since there is limited information for this group. We aimed to describe the above parameters in our cohort of pre-schoolers undergoing a colonoscopy. METHODS: Retrospective review of all colonoscopies in a tertiary pediatric hospital between Dec 1, 2014 to Dec 31, 2020 was undertaken...
May 15, 2023: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/37123710/dermoscopic-nail-disorders-in-school-going-children
#38
JOURNAL ARTICLE
Fatima Zahoor, Arfan Ul Bari, Najia Ahmed, Tariq M Malik, Syed Arbab Shah, Ghazal Afzal
Introduction The majority of nail diseases in children are comparable to those in adults, while there are some physiological changes that start to happen around this age and go away over a few years. These conditions could be symptoms of infections and systemic illnesses. Pediatric nail disorders are typically easy to diagnose clinically, although there are occasionally conditions that masquerade as juvenile nail problems. Dermoscopy has grown in favour as a rapid, easy, non-invasive clinical procedure for examining nail diseases...
March 2023: Curēus
https://read.qxmd.com/read/37118811/paediatric-autoimmune-diseases-with-elane-mutations-associated-with-neutropenia
#39
JOURNAL ARTICLE
Dan Zhang, Gaixiu Su, Sheng Hao, Jianming Lai, Shunqiao Feng
OBJECTIVE: To explore the clinical characteristics of autoimmune diseases in children with ELANE mutations. METHODS: Three cases of children with ELANE mutations manifesting as autoimmune diseases, who were under treatment from April 2020 to May 2021, were retrospectively analysed. RESULTS: Among the three children, two were boys aged 15 years and 22 months (cases 1 and 3) respectively, and the other one was a 22-month-old girl (case 2). All the cases had recurrent infections...
April 28, 2023: Pediatric Rheumatology Online Journal
https://read.qxmd.com/read/36994748/low-birthweight-newborns-in-vanuatu-a-longitudinal-follow-up-study
#40
JOURNAL ARTICLE
Annette Garae, Caleb Vangana, Thyna Orelly, Basil Leodoro, Francis Pulsan, Trevor Duke
AIM: Medical care and technology have increased the survival of low birthweight babies (LBW), but especially in low- and middle-income settings the longer term thriving of such babies is not assured because of their fragility, limited services and difficult access after discharge from hospital. In Vanuatu, a Pacific nation of dispersed islands, improving LBW outcomes and survival remains a significant challenge. In this study, we prospectively document the survival, developmental and nutritional outcomes of a cohort of LBW over the first year of life...
March 30, 2023: Journal of Paediatrics and Child Health
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