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https://www.readbyqxmd.com/read/28816352/pulmonary-artery-wave-propagation-and-reservoir-function-in-conscious-man-impact-of-pulmonary-vascular-disease-respiration-and-dynamic-stress-tests
#1
Junjing Su, Charlotte Manisty, Ulf Simonsen, Luke S Howard, Kim H Parker, Alun D Hughes
Detailed hemodynamic analysis may provide novel insights into the pulmonary circulation. Therefore, wave intensity and reservoir-excess pressure analyses were applied in the pulmonary artery to characterise changes in wave propagation and reservoir function during spontaneous respiration and dynamic stress tests. Right heart catheterisation was performed using a pressure and Doppler flow sensor tipped guidewire to obtain simultaneous pressure and flow velocity measurements in the pulmonary artery in control subjects and patients with pulmonary arterial hypertension (PAH) at rest...
August 17, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28804896/load-dependence-of-myocardial-deformation-variables-a-clinical-strain-echocardiographic-study
#2
M Fredholm, K Jörgensen, E Houltz, S-E Ricksten
BACKGROUND: The effects of left ventricular (LV) loading on myocardial deformation variables are not well-studied in the clinical setting. In the present study, we evaluated the effects of isolated changes in preload, afterload and heart rate on LV longitudinal strain, systolic (SR-S) and early diastolic strain rate (SR-E) in post-cardiac surgery patients. METHODS: Twenty-one patients were studied early after cardiac surgery. Longitudinal myocardial strain and SR were analysed off-line using 2-D speckle echocardiography...
August 13, 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28804009/effects-of-timing-of-whey-protein-intake-on-appetite-and-energy-intake-in-healthy-older-men
#3
Caroline Giezenaar, Zoé Coudert, Abdul Baqeri, Caroline Jensen, Trygve Hausken, Michael Horowitz, Ian Chapman, Stijn Soenen
BACKGROUND: Protein-rich supplements are used widely to prevent and manage malnutrition in older adults. We previously showed that 30 g whey protein ingestion, 3 hours before a buffet meal, suppressed energy intake in young, but not in older men. Information about the impact of the timing of ingestion of protein drinks on the suppression of energy intake in older adults is lacking. OBJECTIVE: The aim of the study was to determine the effect of the timing of whey protein ingestion on appetite and subsequent ad libitum energy intake in healthy older men...
August 10, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28801205/recombinant-laminin-fragments-endowed-with-collagen-binding-activity-a-tool-for-conferring-laminin-like-cell-adhesive-activity-to-collagen-matrices
#4
Ryoko Sato-Nishiuchi, Shaoliang Li, Fumi Ebisu, Kiyotoshi Sekiguchi
Laminins are major components of basement membranes that sustain a wide variety of stem cells. Among 15 laminin isoforms, laminin-511 and its E8 fragment (LM511E8) have been shown to strongly promote the adhesion and proliferation of human pluripotent stem cells. The aim of this study was to endow the cell-adhesive activity of laminin-511 on collagen matrices, thereby fabricating collagen-based culture scaffolds for stem cells with defined composition. To achieve this goal, we utilized the collagen-binding domain (CBD) of fibronectin to immobilize LM511E8 on collagen matrices...
August 8, 2017: Matrix Biology: Journal of the International Society for Matrix Biology
https://www.readbyqxmd.com/read/28797661/patency-and-clinical-outcome-after-stent-placement-for-chronic-obstruction-of-the-inferior-vena-cava
#5
O Grøtta, T Enden, G Sandbæk, G F Gjerdalen, C-E Slagsvold, D Bay, N-E Kløw, A Rosales
OBJECTIVE/BACKGROUND: The objective was to assess the technical success, patency, and clinical outcome after stent placement for chronic obstruction of the inferior vena cava (IVC). METHODS: A retrospective analysis was carried out of patients with chronic IVC obstruction verified with computed tomography and/or magnetic resonance venography, accepted for stent placement at the Norwegian National Unit for Reconstructive Deep Venous Surgery from March 2010 to September 2015...
August 7, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28795839/adverse-heart-lung-interactions-in-ventilator-induced-lung-injury
#6
Bhushan H Katira, Regan E Giesinger, Doreen Engelberts, Diana Zabini, Alik Kornecki, Gail Otulakowski, Takeshi Yoshida, Wolfgang M Kuebler, Patrick J McNamara, Kim A Connelly, Brian P Kavanagh
RATIONALE: The original in vivo study of ventilator-induced lung injury by Webb and Tierney (1974) reported that high VT with zero PEEP caused overwhelming lung injury, subsequently shown by others to be due to lung shear stress. OBJECTIVE: To reproduce the lung injury and edema in the 'Webb and Tierney' study and investigate the mechanism. METHODS: Sprague-Dawley rats (≈400 g) received mechanical ventilation for 60 min according to the protocol of Webb and Tierney (14/0, 30/0, 45/10, 45/0 cmH2O)...
August 10, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28793822/dose-response-head-to-head-comparison-of-inodilators-dobutamine-milrinone-and-levosimendan-in-chronic-experimental-pulmonary-hypertension
#7
Marta Tavares-Silva, Mohamed Alaa, Sara Leite, José Oliveira-Pinto, Lucas Lopes, Adelino F Leite-Moreira, André P Lourenço
The choice of inodilator drug in the acute management of patients with pulmonary hypertension (PH) having right ventricular (RV) failure remains unsettled and challenging. Comprehensive experimental evaluations may provide further insight and fundamental translational research clues to support inodilator selection and clinical trial design. Our aim was to compare acute dose-response hemodynamic effects of inodilators dobutamine (DOB), milrinone (MIL), and levosimendan (LEV) in chronic experimental PH. Seven-week-old male Wistar rats were randomly injected with 60 mg·kg(-1) monocrotaline (MCT) or vehicle (Ctrl, n = 7) and underwent systemic and pulmonary artery (PA) pressure and RV pressure-volume (PV) hemodynamic evaluation under halogenate anesthesia 24 to 30 days after injection...
September 2017: Journal of Cardiovascular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28791849/echocardiographic-assessment-and-n-terminal-pro-brain-natriuretic-peptide-in-hypertensives-with-metabolic-syndrome
#8
Paweł Krzesiński, Beata Uziebło-Życzkowska, Grzegorz Gielerak, Adam Stańczyk, Katarzyna Piotrowicz, Wiesław Piechota, Paweł Smurzyński, Andrzej Skrobowski
BACKGROUND: N-terminal pro-brain natriuretic peptide (NT-proBNP) release is associated with left ventricular expansion and pressure overload. Elevation of serum levels of natriuretic peptides is observed in patients with impaired as well as preserved left ventricular systolic function. High NT-proBNP has been shown to be related not only to preload but also to increased afterload, especially blood pressure and arterial stiffness. OBJECTIVES: The aim of the study was to evaluate the association of NT-proBNP and echocardiographic parameters in hypertensives with metabolic syndrome...
March 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28790928/enhanced-right-chamber-remodeling-in-endurance-ultra-trail-athletes-compared-to-marathon-runners-detected-by-standard-and-speckle-tracking-echocardiography
#9
Kristian Ujka, Luca Bastiani, Gennaro D'Angelo, Bruna Catuzzo, Alessandro Tonacci, Simona Mrakic-Sposta, Alessandra Vezzoli, Guido Giardini, Lorenza Pratali
Background: Strenuous and endurance exercise training have been associated with morphological and functional heart remodeling. Two-dimensional speckle-tracking echocardiography (STE) is a novel technique that allows an accurate quantification of global myocardium deformation. Our aim was to evaluate together left and right cardiac remodeling in different long-distance running athletes: marathon runners (42 km) (M) and endurance mountain runners (>300 Km) (UT). Methods: A total of 92 athletes (70 males, 76%) including 47 M [age 45 ± 7 years; training: 18 (9-53) years(*)days/week], 45 UT [age 42 ± 9, training: 30 (15-66) years(*)days/week] underwent conventional echocardiography and STE (Beyond Diogenes 2...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28790277/-management-of-right-heart-failure-after-cardiac-surgery
#10
Takeo Fujino, Akira Shiose
Perioperative right heart failure(RHF) is an important problem, especially in the field of heart failure surgery. Right ventricular performance is determined by the combination of preload, contractility, heart rate, rhythm and afterload. Many factors influence on these parameters in the perioperative period, and the deterioration of one of them can cause RHF. Recently, we often encounter perioperative RHF after left ventricular assist device (LVAD) implantation, and prompt LVAD pump speed optimization and treatment for RHF is required to avoid complications and hemodynamic deterioration...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28790268/-perioperative-care-of-low-cardiac-output-syndrome
#11
Hiroki Kato, Yoshiro Matsui
Low cardiac syndrome( LOS) is the imbalance of the oxygen supply and demand at the tissue due to reduced oxygen supply by decreased cardiac function. The causes of the cardiac dysfunction are insufficient cardioplegia, elongation of aortic clamp or cardiopulmonary bypass (CPB) duration, incomplete revascularization, and so on. The preventions of LOS are myocardial protections intraoperatively. The most important myocardial protection is to accomplish more quickly, accurately and safety to operation. And today, cardioplegia is essential for surgery requiring CPB...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28774325/what-is-the-impact-of-the-fluid-challenge-technique-on-diagnosis-of-fluid-responsiveness-a-systematic-review-and-meta-analysis
#12
Laura Toscani, Hollmann D Aya, Dimitra Antonakaki, Davide Bastoni, Ximena Watson, Nish Arulkumaran, Andrew Rhodes, Maurizio Cecconi
BACKGROUND: The fluid challenge is considered the gold standard for diagnosis of fluid responsiveness. The objective of this study was to describe the fluid challenge techniques reported in fluid responsiveness studies and to assess the difference in the proportion of 'responders,' (PR) depending on the type of fluid, volume, duration of infusion and timing of assessment. METHODS: Searches of MEDLINE and Embase were performed for studies using the fluid challenge as a test of cardiac preload with a description of the technique, a reported definition of fluid responsiveness and PR...
August 4, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28773217/biosorbents-for-removing-hazardous-metals-and-metalloids
#13
REVIEW
Katsutoshi Inoue, Durga Parajuli, Kedar Nath Ghimire, Biplob Kumar Biswas, Hidetaka Kawakita, Tatsuya Oshima, Keisuke Ohto
Biosorbents for remediating aquatic environmental media polluted with hazardous heavy metals and metalloids such as Pb(II), Cr(VI), Sb(III and V), and As(III and V) were prepared from lignin waste, orange and apple juice residues, seaweed and persimmon and grape wastes using simple and cheap methods. A lignophenol gel such as lignocatechol gel was prepared by immobilizing the catechol functional groups onto lignin from sawdust, while lignosulfonate gel was prepared directly from waste liquor generated during pulp production...
July 26, 2017: Materials
https://www.readbyqxmd.com/read/28771496/an-analytical-solution-for-two-dimensional-vacuum-preloading-combined-with-electro-osmosis-consolidation-using-ekg-electrodes
#14
Yang Shen, Chenchen Qiu, Yande Li, Wen Shi, Xiaoxi Rui
China is a country with vast territory, but economic development and population growth have reduced the usable land resources in recent years. Therefore, reclamation by pumping and filling is carried out in eastern coastal regions of China in order to meet the needs of urbanization. However, large areas of reclaimed land need rapid drainage consolidation treatment. Based on past researches on how to improve the treatment efficiency of soft clay using vacuum preloading combined with electro-osmosis, a two-dimensional drainage plane model was proposed according to the Terzaghi and Esrig consolidation theory...
2017: PloS One
https://www.readbyqxmd.com/read/28764494/bio-inspired-piezoelectric-linear-motor-driven-by-a-single-phase-harmonic-wave-with-an-asymmetric-stator
#15
Qiaosheng Pan, Enming Miao, Bingxuan Wu, Weikang Chen, Xiujun Lei, Liangguo He
A novel, bio-inspired, single-phase driven piezoelectric linear motor (PLM) using an asymmetric stator was designed, fabricated, and tested to avoid mode degeneracy and to simplify the drive mechanism of a piezoelectric motor. A piezoelectric transducer composed of two piezoelectric stacks and a displacement amplifier was used as the driving element of the PLM. Two simple and specially designed claws performed elliptical motion. A numerical simulation was performed to design the stator and determine the feasibility of the design mechanism of the PLM...
July 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28760374/ropivacaine-alters-the-mechanical-properties-of-hamstring-tendons-in-vitro-controlled-mechanical-testing-of-tendons-from-living-donors
#16
Matthieu Ollivier, Jaafar Sbihi, Abderrahmane Sbihi, Martine Pithioux, Sebastien Parratte, Jean-Noel Argenson
OBJECTIVE: Intra-articular or peri-articular injection of ropivacaine (RI) is an element of current knee surgery practices. The goal of this study was to determine the effects of RI on the mechanical properties of hamstring tendons. METHODS: A tensile test to failure was performed on 120 hamstring tendon segments harvested during ACL reconstruction surgery in 120 patients. Two sets of tensile tests were done. The first evaluated the effect of RI itself on the mechanical properties of tendons: 30 samples were soaked for 1 hour in a 2% RI solution and compared to 30 samples soaked in a saline solution (control group)...
July 28, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28759478/the-effects-of-orientation-of-lumbar-facet-joints-on-the-facet-joint-contact-forces-an-in-vitro-biomechanical-study
#17
Xiang Liu, Zhiping Huang, Ruozhou Zhou, Qingan Zhu, Wei Ji, Yaowu Long, Jixing Wang
STUDY DESIGN: A biomechanical human cadaveric study. OBJECTIVE: The aim of this study was to measure L2-L3 facet joint contact forces in a flexibility test using thin film electroresistive sensors, and facet joint orientation on CT scan images, to examine the effects of orientation of lumbar facet joint on the facet joint contact forces. SUMMARY OF BACKGROUND DATA: Biomechanically the bilateral facet joints play a critical role in maintaining stability of the lumbar spine by sharing load...
July 28, 2017: Spine
https://www.readbyqxmd.com/read/28746995/desorption-of-radioactive-cesium-by-seawater-from-the-suspended-particles-in-river-water
#18
Masaki Onodera, Akira Kirishima, Seiya Nagao, Kouichi Takamiya, Tsutomu Ohtsuki, Daisuke Akiyama, Nobuaki Sato
In 2011, the accident at the Fukushima-Daiichi nuclear power plant dispersed radioactive cesium throughout the environment, contaminating the land, rivers, and sea. Suspended particles containing clay minerals are the transportation medium for radioactive cesium from rivers to the ocean because cesium is strongly adsorbed between the layers of clay minerals, forming inner sphere complexes. In this study, the adsorption and desorption behaviors of radioactive cesium from suspended clay particles in river water have been investigated...
October 2017: Chemosphere
https://www.readbyqxmd.com/read/28746064/precannulated-fenestrated-endovascular-aneurysm-repair-using-guidewire-fixator-a-novel-method-using-the-liungman-guidewire-fixator
#19
Linus Bosaeus, Kevin Mani, Anders Wanhainen, Krister Liungman
OBJECTIVE: By using a guidewire fixator, the distal guidewire position can be secured in an artery. This new principle enables a method for fenestrated endovascular aortic repair where the connection between the aortic branches and the stent graft fenestrations is made before inserting and deploying the stent graft. METHODS: This is conducted using a fenestrated stent graft with preloaded catheters, through which the prepositioned and distally secured guidewires from the branches are inserted...
July 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/28741664/in-vitro-evaluation-of-an-immediate-response-starling-like-controller-for-dual-rotary-blood-pumps
#20
Andrew F Stephens, Michael C Stevens, Shaun D Gregory, Matthias Kleinheyer, Robert F Salamonsen
Rotary ventricular assist devices (VADs) are used to provide mechanical circulatory support. However, their lack of preload sensitivity in constant speed control mode (CSC) may result in ventricular suction or venous congestion. This is particularly true of biventricular support, where the native flow-balancing Starling response of both ventricles is diminished. It is possible to model the Starling response of the ventricles using cardiac output and venous return curves. With this model, we can create a Starling-like physiological controller (SLC) for VADs which can automatically balance cardiac output in the presence of perturbations to the circulation...
July 25, 2017: Artificial Organs
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