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Peritonitis Dialysis

M Carolina Rivacoba, M Luisa Ceballos, Paulina Coria
Peritoneal dialysis-related infections are the main complication in pediatric patients undergoing this renal replacement therapy, associating a high rate of morbidity, generating also a decreasing survival of the peritoneal membrane and worsening the patient outcome. We describe the recommended diagnostic and therapeutic modalities to treat dialysis-related in children.
April 2018: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
Gilbert L Queeley, Ellen S Campbell
Background: End-stage renal disease (ESRD) imposes significant economic and social burdens on patients and healthcare systems. In the United States alone, more than 600,000 Americans have ESRD, with an estimated annual cost of treatment of more than $30 billion. Peritoneal dialysis and hemodialysis are competing renal replacement therapies in ESRD; however, data comparing quality-of-life outcomes between these 2 modalities are limited. Objectives: To compare the effectiveness of peritoneal dialysis with the more common treatment modality of hemodialysis on the health-related quality of life (HRQoL) of patients with ESRD in the general, physical, and psychological domains; and to determine whether the time of publication and the origin of each study influenced its findings regarding the effectiveness of the 2 modalities...
May 2018: American Health & Drug Benefits
Antonio Méndez-Durán, Manuel Humberto Ignorosa-Luna, Gilberto Pérez-Aguilar, Francisco Jesús Rivera-Rodríguez, Luis Rafael López-Ocaña
Background: The Instituto Mexicano del Seguro Social (IMSS) is the institution with the greatest health coverage in Mexico. In adherence to existing and committed to provide specialized services to specific populations (vulnerable age groups, such as children and young people in primary, secondary and higher education, productive and without social security educational training), this gives the renal replacement therapy -peritoneal dialysis and hemodialysis- at no cost to students. Methods: Cross-sectional and retrospective study conducted from 1 to 30 September 2016; Census Patients with Chronical Renal Failure, sociodemographic and type of therapy are identified; direct costs are estimated...
March 2018: Revista Médica del Instituto Mexicano del Seguro Social
Amber O Molnar, Louise Moist, Scott Klarenbach, Jean-Philippe Lafrance, S Joseph Kim, Karthik Tennankore, Jeffrey Perl, Joanne Kappel, Michael Terner, Jagbir Gill, Manish M Sood
Background: Hospitalizations of chronic dialysis patients have not been previously studied at a national level in Canada. Understanding the scope and variables associated with hospitalizations will inform measures for improvement. Objective: To describe the risk of all-cause and infection-related hospitalizations in patients on dialysis. Design: Retrospective cohort study using health care administrative databases. Setting: Provinces and territories across Canada (excluding Manitoba and Quebec)...
2018: Canadian Journal of Kidney Health and Disease
Aminu K Bello, Christine M Ribic, Serge H Cournoyer, Mercedeh Kiaii, Martine LeBlanc, Melanie Poulin-Costello, David N Churchill, Norman Muirhead
Background: Several studies have demonstrated harm associated with using erythropoiesis-stimulating agents (ESA) to achieve higher hemoglobin (Hb) levels. Subsequently, more conservative use of ESAs has changed anemia therapy in patients with chronic renal failure. Objective: The objectives were to identify transfusion rates in hemodialysis (HD) patients during the first year of therapy, to identify factors associated with the probability of transfusion, describe reasons for the transfusions, and identify the Hb values associated with each transfusion...
2018: Canadian Journal of Kidney Health and Disease
Jan Galle, Jana Reitlinger
In renal replacement therapy, different methods are available: hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation (KTx). In addition, variants can be used: HD as a home HD or center HD, PD as a conventional PD or automated (cycler) PD, KTx as a potentially short-term predictable living donation or conventional donor kidney donation. The patient and his familiar or caring environment must be informed accordingly. This means first of all: information about which procedures of kidney replacement therapy are possible and can be offered...
June 2018: Deutsche Medizinische Wochenschrift
Shuzo Kaneko, Kunihiro Yamagata
Accumulation of amyloid fibrils from β2-microglobulin (β2M) was first recognized as a characteristic osteoarticular complication in long-term hemodialysis (HD) patients and called "HD-related amyloidosis" (HRA). However, this syndrome can also be observed in end-stage renal diseases (ESRD) patients undergoing peritoneal dialysis, and even in patients with chronic renal failure before the initiation of dialytic therapy, suggesting that HD is not a direct cause but that accumulation of β2M or some β2M-associated molecules in the body is a common pathogenesis...
June 12, 2018: Seminars in Dialysis
Cheuk-Chun Szeto, Gordon Chun-Kau Chan, Jack Kit-Chung Ng, Kai-Ming Chow, Bonnie Ching-Ha Kwan, Phyllis Mei-Shan Cheng, Vickie Wai-Ki Kwong, Man-Ching Law, Chi-Bon Leung, Philip Kam-Tao Li
BACKGROUND/AIMS: Frailty and depression both contribute to malnutrition and adverse clinical outcome of peritoneal dialysis (PD) patients. However, their interaction is incompletely defined. METHODS: We studied 178 adult Chinese PD patients. Physical frailty was assessed by a validated in-house questionnaire; depressive symptoms was screened by the Geriatric Depression Scale; nutritional status was determined by subjective global assessment (SGA) and malnutrition inflammation score (MIS)...
June 7, 2018: Kidney & Blood Pressure Research
Xiaoxue Zhang, Ying Chen, Yamei Cai, Xing Tian, Jing Xiao, Zhanzheng Zhao, Dahai Yu
INTRODUCTION: This study aimed to assess the number and profiles of patients initializing peritoneal dialysis form the Henan Peritoneal Dialysis Registry, a provincial database in central China. MATERIALS AND METHODS: All patients aged 18 years and greater, initializing peritoneal dialysis within the province during 2007 to 2014 were included. Demographic characteristics were collected and clinical parameters included the type of renal diagnosis (primary glomerular, secondary glomerular, and others) and recorded major comorbidities in the neural, cardiovascular, respiratory, gastrointestinal, and endocrine systems...
May 2018: Iranian Journal of Kidney Diseases
Ying-Han Lin, Yue Chen, Trever C Smith, S L Rajasekhar Karna, J Seshu
Borrelia burgdorferi (Bb ) responds to a variety of host-derived factors and appropriately alters its gene expression for adaptation under different host-specific conditions. We previously showed that varying levels of acetate, a <u>S</u>hort-<u>C</u>hain <u>F</u>atty <u>A</u>cid (SCFA), altered the protein profile of Bb In this study, we determined the effects of other physiologically relevant SCFAs in the regulation of metabolic/virulence-associated proteins using mutant borrelial strains...
June 11, 2018: Infection and Immunity
Qiuyuan Shao, Yangyang Xia, Min Zhao, Jing Liu, Qingyan Zhang, Bo Jin, Jun Xie, Biao Xu, Rujun Gong, Chunming Jiang
Aims: To evaluate the effectiveness and safety of peritoneal dialysis (PD) in treating refractory congestive heart failure (RCHF) with cardiorenal syndrome (CRS). Methods: A total of 36 patients with RCHF were divided into type 2 CRS group (group A) and non-type 2 CRS group (group B) according to the patients' clinical presentations and the ratio of serum urea to creatinine and urinary analyses in this prospective study. All patients were followed up till death or discontinuation of PD...
2018: BioMed Research International
Yu-Hsien Lai, Chih-Hsien Wang, Jen-Pi Tsai, Jia-Sian Hou, Chung-Jen Lee, Bang-Gee Hsu
Objective: Peripheral artery disease (PAD) is associated with systemic atherosclerosis and indicates an increased risk of mortality in peritoneal dialysis (PD) patients. A high leptin level accelerates atherosclerosis in apoE-deficient mice. The purpose of this study was to examine the association of serum leptin level and PAD in adult PD patients. Materials and Methods: The clinical characteristics of sixty PD patients recruited from June 2015 to October 2016 were obtained...
April 2018: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
Hugo Ferreira, Ana T Nunes, Ana Oliveira, Ana Beco, Joana Santos, Manuel Pestana
BACKGROUND: Peritoneal dialysis (PD) is an effective renal replacement technique. However, every year a considerable number of patients are transferred to hemodialysis (HD). Our aim was to identify those at risk, in order to place an arteriovenous fistula (AVF). METHODS: Case-control study enrolling all prevalent patients in 2014 and 2015 in our clinic. Groups: 72 case patients who were transferred definitively to HD, 111 control patients (remaining on PD, transplanted, recovered renal function, or deceased)...
June 6, 2018: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Abdullah K Al-Hwiesh
BACKGROUND: The aim of this paper was to review the feasibility of peritoneal dialysis (PD) in the presence of a permanent suprapubic catheter over a long follow-up period. METHODS: Twelve patients with automated PD and permanent suprapubic catheters were studied for complications over a period of 10 years. RESULTS: In all 12 patients, PD went smoothly. Two of our patients required removal of the PD catheter due to peritonitis. The overall rate of exit-site infection throughout the study was 41...
June 6, 2018: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Ludimila G Campos, Jennifer Bragg-Gresham, Yun Han, Thyago P Moraes, Ana E Figueiredo, Pasqual Barretti, Rajesh Balkrishnan, Rajiv Saran, Roberto Pecoits-Filho
INTRODUCTION: Patients on peritoneal dialysis (PD) suffer from a high burden of comorbidities, which are managed with multiple medications. Determinants of prescription patterns are largely unknown in this population. This study assesses temporal changes and factors associated with medication prescription in a nationally representative population of patients on PD under the universal coverage healthcare system in Brazil. METHODS: Incident patients recruited in the Brazilian Peritoneal Dialysis Study (BRAZPD) from December 2004 to January 2011, stratified by prior hemodialysis (HD) treatment, were included in the analysis...
June 6, 2018: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Yu Heng Kwan, Warren Fong, Priscilla How, Hwee-Lin Wee, Ying Ying Leung, Jie Kie Phang, Nai Lee Lui, Chuen Seng Tan, Rahul Malhotra, Truls Østbye, Julian Thumboo
PURPOSE: The purpose of the study was to assess the impact of axial spondyloarthritis (axSpA) on patients' quality of life (QoL) compared to patients with moderate to end-stage chronic kidney disease (CKD). METHODS: We conducted secondary analysis of QoL data obtained from patients with axSpA and CKD from 2011 to 2014. QoL was assessed using the SF-36 version 2 and KDQoL-SF for patients with axSpA and CKD, respectively. Patients with CKD were subcategorized to CKD-pre-dialysis, hemodialysis (CKD-HD) and peritoneal dialysis (CKD-PD)...
June 5, 2018: Quality of Life Research
Yunfang Zhang, Junxia Feng, Qi Wang, Shili Zhao, Jiaqi Xu, Hongyan Li
Peritonitis is still a major cause of the death in peritoneal dialysis (PD) patients despite the significant decline of the peritonitis rates in recent years. This study is designed to evaluate the therapeutic potential of peroxisome proliferator-activated receptor-γ agonist, rosiglitazone, on the structure and function of the peritoneum in a peritoneal dialysis (PD) rat accompanied with peritonitis induced by lipopolysaccharide (LPS). Our data showed that the peritoneal membrane in the LPS-only group showed increased peritoneal thickness, vessel density and hypercellularity compared with the PD-only group...
June 5, 2018: Bioscience Reports
S D Hwang, J H Lee, S W Lee, J K Kim, M-J Kim, J H Song
BACKGROUND: Reactivation of BK polyomavirus causes destructive virus allograft nephropathy; however, treatment options are limited. Herein, we report a case in which a patient with T cell-mediated rejection was treated with steroid therapy. The patient subsequently developed BK viremia and was successfully treated by using intravenous immunoglobulin (IVIG) after failing to respond to conventional treatment. CASE PRESENTATION: A 54-year-old man had been undergoing peritoneal dialysis for 3 years before kidney transplantation...
June 2, 2018: Transplantation Proceedings
Joana Gameiro, Sofia Jorge, José António Lopes
Heparin-induced thrombocytopenia (HIT) is a serious and life-threatening complication that occurs in five per cent of patients exposed to heparin. It should be considered in patients with a platelet count <100×109 cells/l or a >50% decrease from baseline count in association with heparin therapy. Thromboembolic complications develop in 50% of patients. Bleeding is rare as the platelet count nadir typically does not drop below 20×109 cells/l. Up to 12% of dialysis patients develop HIT, named haemodialysis-related-heparin-induced thrombocytopenia (HD-HIT), as they are a risk group with continuous exposure to heparin...
June 2, 2018: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
Sanjay R Kharche, Aaron So, Fabio Salerno, Ting-Yim Lee, Chris Ellis, Daniel Goldman, Christopher W McIntyre
Dialysis prolongs life but augments cardiovascular mortality. Imaging data suggests that dialysis increases myocardial blood flow (BF) heterogeneity, but its causes remain poorly understood. A biophysical model of human coronary vasculature was used to explain the imaging observations, and highlight causes of coronary BF heterogeneity. Post-dialysis CT images from patients under control, pharmacological stress (adenosine), therapy (cooled dialysate), and adenosine and cooled dialysate conditions were obtained...
2018: Frontiers in Physiology
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