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https://www.readbyqxmd.com/read/28638191/tai-chi-for-schizophrenia-a-systematic-review
#1
Wei Zheng, Qiang Li, Jingxia Lin, Yingqiang Xiang, Tong Guo, Qiong Chen, Dongbin Cai, Yutao Xiang
BACKGROUND: Tai Chi as a form of moderate aerobic exercise originating in China, could promote balance and healing of the mind-body. Furthermore, Tai Chi has been used as an adjunctive treatment for patients with schizophrenia. However, no meta-analysis or systematic review on adjunctive Tai Chi for patients with schizophrenia has yet been reported. AIM: A systematic review and meta-analysis was conducted to examine the efficacy of Tai Chi as an adjunctive treatment for schizophrenia using randomized controlled trial (RCT) data...
August 25, 2016: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/28613395/clozapine-dose-for-schizophrenia
#2
REVIEW
Selvizhi Subramanian, Birgit A Völlm, Nick Huband
BACKGROUND: Schizophrenia and related disorders such as schizophreniform and schizoaffective disorder are serious mental illnesses characterised by profound disruptions in thinking and speech, emotional processes, behaviour and sense of self. Clozapine is useful in the treatment of schizophrenia and related disorders, particularly when other antipsychotic medications have failed. It improves positive symptoms (such as delusions and hallucinations) and negative symptoms (such as withdrawal and poverty of speech)...
June 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28613384/communication-skills-training-for-mental-health-professionals-working-with-people-with-severe-mental-illness
#3
REVIEW
Alexia Papageorgiou, Yoon K Loke, Michelle Fromage
BACKGROUND: Research evidence suggests that both mental health professionals and people with severe mental health illness such as schizophrenia or schizoaffective disorder find it difficult to communicate with each other effectively about symptoms, treatments and their side effects so that they reach a shared understanding about diagnosis, prognosis and treatment. Effective use of communication skills in mental health interactions could be associated with increased patient satisfaction and adherence to treatment...
June 13, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28608575/association-between-comt-val158met-and-psychiatric-disorders-a-comprehensive-meta-analysis
#4
Steven Taylor
Catechol-O-methyltransferase (COMT) Val158Met is widely regarded as potentially important for understanding the genetic etiology of many different psychiatric disorders. The present study appears to be the first comprehensive meta-analysis of COMT genetic association studies to cover all psychiatric disorders for which there were available data, published in any language, and with an emphasis on investigating disorder subtypes (defined clinically or by demographic or other variables). Studies were included if they reported one or more datasets (i...
June 13, 2017: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://www.readbyqxmd.com/read/28603875/impairments-of-spontaneous-and-deliberative-mentalizing-co-occur-yet-dissociate-in-schizophrenia
#5
Robyn Langdon, Michaela Flynn, Emily Connaughton, Martin Brüne
OBJECTIVES: Evidence of impairment in explicit mentalizing in people with schizophrenia has inspired interventions to improve awareness of others' mental states in these individuals. Less is known of implicit mentalizing in schizophrenia, with current findings mixed. We sought to resolve previous inconsistencies using Heider & Simmel's (H&S) classic animation to elicit spontaneous mentalizing and examined relations between spontaneous and deliberative mentalizing. METHODS: Forty-five schizophrenia outpatients and 27 general-community controls completed two explicit theory-of-mind (TOM) tasks and then described the H&S animation (to elicit spontaneous social attributions about emotionally driven, as well as goal-driven, behaviours), before and after an instruction to think of the shapes as people...
June 12, 2017: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28588433/intragenic-cntnap2-deletions-a-bridge-too-far
#6
REVIEW
Martin Poot
Intragenic deletions of the contactin-associated protein-like 2 gene (CNTNAP2) have been found in patients with Gilles de la Tourette syndrome, intellectual disability (ID), obsessive compulsive disorder, cortical dysplasia-focal epilepsy syndrome, autism, schizophrenia, Pitt-Hopkins syndrome, stuttering, and attention deficit hyperactivity disorder. A variety of molecular mechanisms, such as loss of transcription factor binding sites and perturbation of penetrance and expressivity, have been proposed to account for the phenotypic variability resulting from CNTNAP2 mutations...
May 2017: Molecular Syndromology
https://www.readbyqxmd.com/read/28572034/decreased-middle-temporal-gyrus-connectivity-in-the-language-network-in-schizophrenia-patients-with-auditory-verbal-hallucinations
#7
Linchuan Zhang, Baojuan Li, Huaning Wang, Liang Li, Qimei Liao, Yang Liu, Xianghong Bao, Wenlei Liu, Hong Yin, Hongbing Lu, Qingrong Tan
As the most common symptoms of schizophrenia, the long-term persistence of obstinate auditory verbal hallucinations (AVHs) brings about great mental pain to patients. Neuroimaging studies of schizophrenia have indicated that AVHs were associated with altered functional and structural connectivity within the language network. However, effective connectivity that could reflect directed information flow within this network and is of great importance to understand the neural mechanisms of the disorder remains largely unknown...
May 29, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28560267/electroconvulsive-therapy-induced-brain-functional-connectivity-predicts-therapeutic-efficacy-in-patients-with-schizophrenia-a-multivariate-pattern-recognition-study
#8
Peng Li, Ri-Xing Jing, Rong-Jiang Zhao, Zeng-Bo Ding, Le Shi, Hong-Qiang Sun, Xiao Lin, Teng-Teng Fan, Wen-Tian Dong, Yong Fan, Lin Lu
Previous studies suggested that electroconvulsive therapy can influence regional metabolism and dopamine signaling, thereby alleviating symptoms of schizophrenia. It remains unclear what patients may benefit more from the treatment. The present study sought to identify biomarkers that predict the electroconvulsive therapy response in individual patients. Thirty-four schizophrenia patients and 34 controls were included in this study. Patients were scanned prior to treatment and after 6 weeks of treatment with antipsychotics only (n = 16) or a combination of antipsychotics and electroconvulsive therapy (n = 13)...
2017: NPJ Schizophrenia
https://www.readbyqxmd.com/read/28548580/a-review-of-the-impact-of-exclusion-criteria-on-the-generalizability-of-schizophrenia-treatment-research
#9
Keith Humphreys
Treatment research studies employ criteria that determine which patients are eligible to participate and which are not. When such exclusion criteria produce a treatment research sample that is a small and unrepresentative subset of all patients with a particular disease, clinicians may be hesitant to apply the research results in front-line clinical practice. Accordingly, the present paper reviews the English-language literature on exclusion criteria in schizophrenia treatment research and draws initial conclusions about their impact...
2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28528230/effect-of-childhood-trauma-on-cognitive-functions-in-a-sample-of-chinese-patients-with-schizophrenia
#10
Xian-Bin Li, Qi-Jing Bo, Guang-Ping Zhang, Wei Zheng, Zhi-Min Wang, An-Ning Li, Qing Tian, Jin-Tong Liu, Yi-Lang Tang, Chuan-Yue Wang
In this study, we aimed to determine the influence of various types of childhood trauma (CT) on cognitive functions in Chinese patients presented with schizophrenia. One hundred sixty-two patients were assessed with the Childhood Trauma Questionnaire-Short Form (CTQ-SF) and Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). We investigated the correlations between various types of CT, demographic characteristics, and cognitive functions. Significant negative correlations were observed in physical abuse (PA) and sexual abuse (SA) with the language score (r=-0...
July 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28516224/psychiatric-behaviors-associated-with-cytoskeletal-defects-in-radial-neuronal-migration
#11
REVIEW
Toshifumi Fukuda, Shigeru Yanagi
Normal development of the cerebral cortex is an important process for higher brain functions, such as language, and cognitive and social functions. Psychiatric disorders, such as schizophrenia and autism, are thought to develop owing to various dysfunctions occurring during the development of the cerebral cortex. Radial neuronal migration in the embryonic cerebral cortex is a complex process, which is achieved by strict control of cytoskeletal dynamics, and impairments in this process are suggested to cause various psychiatric disorders...
May 17, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/28515818/pharmacogenomic-testing-for-psychotropic-medication-selection-a-systematic-review-of-the-assurex-genesight-psychotropic-test
#12
(no author information available yet)
BACKGROUND: A large proportion of the Ontario population lives with a diagnosed mental illness. Nearly 5% of Ontarians have major depressive disorder, and another 5% have another type of depressive disorder, bipolar disorder, schizophrenia, anxiety, or some other disorder not otherwise specified. Medications are commonly used to treat mental illness, but choosing the right medication for each patient is challenging, and more than 40% of patients discontinue their medication within 90 days because of adverse effects or lack of response...
2017: Ontario Health Technology Assessment Series
https://www.readbyqxmd.com/read/28515552/the-influence-of-psychosocial-dysfunctions-in-chronic-schizophrenia-patients-in-remission-a-hospital-based-study
#13
Sarada Prasanna Swain, Sushree Sangita Behura, Manoj Kumar Dash, Anil Kumar Nayak, Saswati Sucharita Pati
BACKGROUND: Psychosocial dysfunctions in the various psychosocial areas in chronic schizophrenic patients predict the long-term course, outcome, and quality of life of these patients, which always varies with years of treatment. OBJECTIVE: To know the influence and compare the level of psychosocial dysfunctions and severity of disability burden in chronic schizophrenic patients who are in remission with duration of 5 and 20 years. MATERIALS AND METHODS: The sample was collected from the OPD of Mental Health Institute (COE), S...
March 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28514778/validation-of-the-five-factor-model-of-the-arabic-version-of-the-positive-and-negative-syndrome-scale-in-schizophrenia
#14
Arij Yehya, Suhaila Ghuloum, Ziyad Mahfoud, Mark Opler, Anzalee Khan, Samer Hammoudeh, Yahya Hani, Hassen Al-Amin
BACKGROUND: The Positive and Negative Syndrome Scale (PANSS) is a widely used assessment for patients with schizophrenia across clinical and research settings. This scale allows the classification of the psychotic symptoms to better understand the psychopathology in patients with schizophrenia. There are no available data on the different components of psychopathology in Arab patients with schizophrenia. OBJECTIVES: This study examined the factor structure of the validated Arabic version of the PANSS in a sample of Arab patients with schizophrenia...
May 18, 2017: Psychopathology
https://www.readbyqxmd.com/read/28500472/impaired-interpretation-of-others-behavior-is-associated-with-difficulties-in-recognizing-pragmatic-language-in-patients-with-schizophrenia
#15
Keita Fukuhara, Yasuhiro Ogawa, Hiroyuki Tanaka, Yuma Nagata, Saiji Nishida, Daisuke Haga, Takashi Nishikawa
Much attention has been paid to the pragmatic language function in schizophrenia. This study of Japanese patients with schizophrenia examined the relationship between impaired interpretation of the behaviors of other people in social contexts and the ability to recognize metaphor and irony. We assessed 34 patients with schizophrenia and 34 normal subjects using first- and second-order theory of mind tasks, the Metaphor and Sarcasm Scenario Test, and the Dewey Story Test (which tests the ability to judge others' social behaviors)...
May 12, 2017: Journal of Psycholinguistic Research
https://www.readbyqxmd.com/read/28499897/reduced-language-lateralization-in-first-episode-schizophrenia-a-near-infrared-spectroscopy-study
#16
Po-Han Chou, Wei-Hao Lin, Wang-Rung Li, Chih-Mao Huang, Chia-Wei Sun
BACKGROUND: Diminished functional lateralization in language-related areas is found in chronic schizophrenia (SZ). However, whether this reduced lateralization exists at the early stage of SZ remains unclear. The present study aimed to investigate language lateralization in first episode schizophrenia (FES) using near infrared spectroscopy (NIRS) during a letter version of verbal fluency test (VFT). METHODS: A total of 28 FES patients and 33 healthy controls (HCs) underwent NIRS while performing a VFT...
May 9, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28498576/a-critique-of-the-ultra-high-risk-and-transition-paradigm
#17
Jim van Os, Sinan Guloksuz
The transdiagnostic expression of psychotic experiences in common mental disorder (anxiety/depression/substance use disorder) is associated with a poorer prognosis, and a small minority of people may indeed develop a clinical picture that meets criteria for schizophrenia. However, it appears neither useful nor valid to observe early states of multidimensional psychopathology in young people through the "schizo"-prism, and apply misleadingly simple, unnecessary and inefficient binary concepts of "risk" and "transition"...
June 2017: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://www.readbyqxmd.com/read/28498088/mental-health-problems-of-second-generation-children-and-adolescents-with-migration-background
#18
Veysi Ceri, Zeliha Özlü-Erkilic, Ürün Özer, Tayyib Kadak, Dietmar Winkler, Burak Dogangün, Türkan Akkaya-Kalayci
OBJECTIVE: Despite the growing number of young second-generation immigrant (SGI) children and adolescents, studies about their mental health are rare. The objective of this study was to investigate the mental health problems of SGI children and adolescents in Istanbul, Turkey. METHODS: In a clinical sample the mental health of 54 SGIs and 50 native children and adolescents were examined using the Schedule for Affective Disorders and Schizophrenia for School Aged Children-Present and Lifetime Version (K-SADS-PL) and Children's Global Assessment Scale...
February 24, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28489133/association-between-antipsychotics-and-cardiovascular-adverse-events-a-systematic-review
#19
Ana Amancio Santos Da Silva, Marina Viegas Moura Rezende Ribeiro, Célio Fernando de Sousa-Rodrigues, Fabiano Timbó Barbosa
Objective: Determine whether there is an association between the risk of cardiovascular adverse events and the use of antipsychotic agents. Method: Analysis of original articles retrieved from the following databases: LILACS, PubMed, Cochrane Controlled Trials Clinical Data Bank (CENTRAL) and PsycINFO, without language restriction, dated until November 2015. After screening of 2,812 studies, three cohort original articles were selected for quality analysis. Results: 403,083 patients with schizophrenia and 119,015 participants in the control group data were analyzed...
March 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28479803/psychiatric-presentations-heralding-hashimoto-s-encephalopathy-a-systematic-review-and-analysis-of-cases-reported-in-literature
#20
REVIEW
Vikas Menon, Karthick Subramanian, Jaiganesh Selvapandian Thamizh
Hashimoto's encephalopathy (HE) may often present initially with psychiatric symptoms. These presentations are often variable in clinical aspects, and there has been no systematic analysis of the numerous psychiatric presentations heralding an eventual diagnosis of HE which will guide clinicians to make a correct diagnosis of HE. This systematic review was done to analyze the demographic characteristics, symptom typology, and clinical and treatment variables associated with such forerunner presentations. Electronic databases such as PubMed, ScienceDirect, and Google Scholar databases were searched to identify potential case reports that described initial psychiatric presentations of HE in English language peer-reviewed journals...
April 2017: Journal of Neurosciences in Rural Practice
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